@TOME V2.3
(Nov 2016)

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Alignment:

3D Common Core:

Structural Clustering:

Modeller Result :

Complexes Modeling
Templates Information:
Sequence & Result Tab:

Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : LTK_HUMAN: (2013-07-22 )
MGCWGQLLVWFGAAGAILCSSPGSQETFLRSSPLPLASPSPRDPKVSAPPSILEPASPLNSPGTEGSWLFSTCGASGRHGPTQTQCDGAYAGTSVVVTVGAAGQLRGVQLWRVPGPGQYLISAYGAAGGKGAKNHLSRAHGVFVSAIFSLGLGESLYILVGQQGEDACPGGSPESQLVCLGESRAVEEHAAMDGSEGVPGSRRWAGGGGGGGGATYVFRVRAGELEPLLVAAGGGGRAYLRPRDRGRTQASPEKLENRSEAPGSGGRGGAAGGGGGWTSRAPSPQAGRSLQEGAEGGQGCSEAWATLGWAAAGGFGGGGGACTAGGGGGGYRGGDASETDNLWADGEDGVSFIHPSSELFLQPLAVTENHGEVEIRRHLNCSHCPLRDCQWQAELQLAECLCPEGMELAVDNVTCMDLHKPPGPLVLMVAVVATSTLSLLMVCGVLILVKQKKWQGLQEMRLPSPELELSKLRTSAIRTAPNPYYCQVGLGPAQSWPLPPGVTEVSPANVTLLRALGHGAFGEVYEGLVIGLPGDSSPLQVAIKTLPELCSPQDELDFLMEALIISKFRHQNIVRCVGLSLRATPRLILLELMSGGDMKSFLRHSRPHLGQPSPLVMRDLLQLAQDIAQGCHYLEENHFIHRDIAARNCLLSCAGPSRVAKIGDFGMARDIYRASYYRRGDRALLPVKWMPPEAFLEGIFTSKTDSWSFGVLLWEIFSLGYMPYPGRTNQEVLDFVVGGGRMDPPRGCPGPVYRIMTQCWQHEPELRPSFASILERLQYCTQDPDVLNSLLPMELGPTPEEEGTSGLGNRSLECLRPPQPQELSPEKLKSWGGSPLGPWLSSGLKPLKSRGLQPQNLWNPTYRS

Atome Classification :

(62 SA) .........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500....-...510.-.-.....520.......530..-.-.--...540.......550.....-..560......-.570...----....580....-...590.......600..-...------..------610---.--.--..----...620.......630.......640.......650.....--..660.......--670..-.....680.......690.......700.......710.......720....-...730.......740.......750.......760.......770.......780.-......790.......800.......810.......820.......830.......840.......850.......860..
(Atome) (Ident) (Tito) (Num) (Ligand) (Uniprot) MGCWGQLLVWFGAAGAILCSSPGSQETFLRSSPLPLASPSPRDPKVSAPPSILEPASPLNSPGTEGSWLFSTCGASGRHGPTQTQCDGAYAGTSVVVTVGAAGQLRGVQLWRVPGPGQYLISAYGAAGGKGAKNHLSRAHGVFVSAIFSLGLGESLYILVGQQGEDACPGGSPESQLVCLGESRAVEEHAAMDGSEGVPGSRRWAGGGGGGGGATYVFRVRAGELEPLLVAAGGGGRAYLRPRDRGRTQASPEKLENRSEAPGSGGRGGAAGGGGGWTSRAPSPQAGRSLQEGAEGGQGCSEAWATLGWAAAGGFGGGGGACTAGGGGGGYRGGDASETDNLWADGEDGVSFIHPSSELFLQPLAVTENHGEVEIRRHLNCSHCPLRDCQWQAELQLAECLCPEGMELAVDNVTCMDLHKPPGPLVLMVAVVATSTLSLLMVCGVLILVKQKKWQGLQEMRLPSPELELSKLRTSAIRTAPNPYYCQVGLGPAQSWPLPPGVTEVS-PANVTLL-R-ALGHGAFGEVYEGLVIGLPG-D-S--SPLQVAIKTLPELCSPQDELD-FLMEALIISKF-RHQNIVR----CVGLSLRATPR-LILLELMSGGDMKSFLRH-SRP------HL------GQP---S--P--LV----MRDLLQLAQDIAQGCHYLEENHFIHRDIAARNCLLSCAGPS--RVAKIGDFGMAR--DIYRA-SYYRRGDRALLPVKWMPPEAFLEGIFTSKTDSWSFGVLLWEIFSLGYMPYPG-RTNQEVLDFVVGGGRMDPPRGCPGPVYRIMTQCWQHEPELRPSFASILERLQYCTQD-PDVLNSLLPMELGPTPEEEGTSGLGNRSLECLRPPQPQELSPEKLKSWGGSPLGPWLSSGLKPLKSRGLQPQNLWNPTYRS
6 PsiBlast_PDB 90.6873%-112 - C1 -3LCS A:[30-333] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YCFAGKTSSIS-----DLKEVP-RKNITLI-R-GLGHGAFGEVYEGQVSGMPN-D-P--SPLQVAVKTLPEVCSEQDELD-FLMEALIISKF-NHQNIVR----CIGVSLQSLPR-FILLELMAGGDLKSFLRE-TRP------RP------SQP---S--S--LA----MLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCPGPG--RVAKIGDFGMAR--DIYRA-GYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPS-KSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIILERIEYCTQD-PDVINTALPI-----------------------------------------------------------------------
117 HHSearch 90.4673%-110 - C1 -3L9P A:[50-357] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NPNYCFAGKTSS-----ISDLKEVP-RKNITLI-R-GLGHGAFGEVYEGQVSG---------SPLQVAVKTLPEVCSEQDELD-FLMEALIISKF-NHQNIVR----CIGVSLQSLPR-FILLELMAGGDLKSFLRE-TRP------RP------SQP---S--S--LA----MLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCPGPG--RVAKIGDFGMAR--DIYRA-GYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPS-KSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIILERIEYCTQD-PDVINTALPIE----------------------------------------------------------------------
11 PsiBlast_PDB 90.4373%-117 - C1 -4FNY A:[20-321] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SSIS-----DLKEVP-RKNITLI-R-GLGH---GEVYEGQVSG----------PLQVAVKTLPEVCSEQDELD-FLMEALIISKF-NHQNIVR----CIGVSLQSLPR-FILLELMAGGDLKSFLRE-TRP------RP---------------S--LA----MLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCPGPG--RVAKIGDF-------------------CAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPS-KSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIILERIEYCTQD-PDVINTALPIEYGPL------------------------------------------------------------------
8 PsiBlast_PDB 90.4173%-111 - C1 -4FOD A:[8-328] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TSTIMTDYNPNYSFAGKTSSIS-----DLKEVP-RKNITLI-R-GLGHGAFGEVYEGQVS----------SPLQVAVKTLPEVCSEQDELD-FLMEALIISKF-NHQNIVR----CIGVSLQSLPR-FILLELMAGGDLKSFLRE-TRP------RP------SQP---S--S--LA----MLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCPGPG--RVAKIGDFGMAR--DIYRA--------CAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPS-KSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIILERIEYCTQD-PDVINTALPIEYGPLV-----------------------------------------------------------------
2 PsiBlast_PDB 90.2672%-115 - C1 -4FOC A:[36-345] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NPNYSFAGKTSSIS-----DLKEVP-RKNITLI-R-GLGHGAFGEVYEGQVS----------SPLQVAVKTLPEVCSEQDELD-FLMEALIISKF-NHQNIVR----CIGVSLQSLPR-FILLELMAGGDLKSFLRE-TRP------RP------SQP---S--S--LA----MLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCPGPG--RVAKIGDFGMAR--DIYR---------CAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPS-KSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIILERIEYCTQD-PDVINTALPIEYG--------------------------------------------------------------------
1 PsiBlast_PDB 89.4872%-114 - C1 -4FOB A:[36-345] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NPNYSFAGKTSSIS-----DLKEVP-RKNITLI-R-GLGHGAFGEVYEGQVS----------SPLQVAVKTLPEVCSEQDELD-FLMEALIISKF-NHQNIVR----CIGVSLQSLPR-FILLELMAGGDLKSFLRE-TRP------RP------------S--S--LA----MLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCPGPG--RVAKIGDFGMAR--DIYRA-------GCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPS-KSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIILERIEYCTQD-PDVINTALPIEYG--------------------------------------------------------------------
23 PsiBlast_CBE 89.4074%-117 - C1 -2XB7 A:[3-309] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NYCFAGKTSSIS-----DLKEVP-RKNITLI-R-GLGHGAFGEVYEGQVS-----------PLQVAVKTLPEVCSEQDELD-FLMEALIISKF-NHQNIVR----CIGVSLQSLPR-FILLELMAGGDLKSFLRE-TRP------RP------SQP---S--S--LA----MLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCPGPG--RVAKIGDFGMA-----------------AMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPS-KSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIILERIEYCTQD-PDVINTALPIEY---------------------------------------------------------------------
3 PsiBlast_PDB 89.1173%-113 - C1 -3AOX A:[19-334] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------STIMTDYNPNYCFAGKTSSIS-----DLKEVP-RKNITLI-R-GLG----GEVYEGQVS-----------PLQVAVKTLPEVCSEQDELD-FLMEALIISKF-NHQNIVR----CIGVSLQSLPR-FILLELMAGGDLKSFLRE-TRP------RP------SQP---S--S--LA----MLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCPGPG--RVAKIGDFGMAR--DIYRA--------CAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPS-KSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIILERIEYCTQD-PDVINTALPIEY---------------------------------------------------------------------
5 PsiBlast_PDB 88.9373%-109 - C1 -3LCT A:[27-334] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NPNYCFAGKTSSIS-----DLKEVP-RKNITLI-R-GLGHGAFGEVYEGQVSGMPN-D-P--SPLQVAVKTLPEVCSEQDELD-FLMEALIISKF-NHQNIVR----CIGVSLQSLPR-FILLELMAGGDLKSFLRE-TRP------RP------SQP---S--S--LA----MLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCPGPG--RVAKIGDFGMAR--DIYRA-GYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPS-KSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIILERIEYCTQD-PDVINTALPIE----------------------------------------------------------------------
9 PsiBlast_PDB 88.6773%-112 - C1 -4FNZ A:[10-319] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NPNYSFAGKTSSIS-----DLKEVP-RKNITLI-R-GLGH---GEVYEGQVSG---------SPLQVAVKTLPEVCSEQDELD-FLMEALIISKF-NHQNIVR----CIGVSLQSLPR-FILLELMAGGDLKSFLRE-TRP------RP------SQP---S--S--LA----MLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCPGPG--RVAKIGDF------------------GCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPS-KSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIILERIEYCTQD-PDVINTALPIEYG--------------------------------------------------------------------
7 PsiBlast_PDB 88.1773%-111 - C1 -4DCE ALK_HUMAN A:[16-325] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NPNYSFAGKTSSIS-----DLKEVP-RKNITLI-R-GLGH---GEVYEGQVS-------P--SPLQVAVKTLPEVCSEQDELD-FLMEALIISKF-NHQNIVR----CIGVSLQSLPR-FILLELMAGGDLKSFLRE-TRP------RP------SQP---S--S--LA----MLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCPGPG--RVAKIGDF-----------------GGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPS-KSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIILERIEYCTQD-PDVINTALPIEYG--------------------------------------------------------------------
21 PsiBlast_CBE 87.9573%-116 - C1 -4DCE B:[17-325] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PNYSFAGKTSSIS-----DLKEVP-RKNITLI-R-GLGH----EVYEGQVS----------SPLQVAVKTLPEVCSEQDELD-FLMEALIISKF-NHQNIVR----CIGVSLQSLPR-FILLELMAGGDLKSFLRE-TRP------RP------SQP---S--S--LA----MLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCPGPG--RVAKIGDF------------------GCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPS-KSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIILERIEYCTQD-PDVINTALPIEYG--------------------------------------------------------------------
30 PsiBlast_CBE 74.0343%-109 - C1 -3LW0 IGF1R_HUMAN B:[7-285] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PDEWEVA-REKITMS-R-ELGQGSFGMVYEGVAKGVVK-D-E--PETRVAIKTVNEAASMRERIE-FLNEASVMKEF-NCHHVVR----LLGVVSQGQPT-LVIMELMTRGDLKSYLRS-LRP-----------------------P--PS----LSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVA---ED--FTVKIGDFGMTR--DIYET-DYYRKG---LLPVRWMSPESLKDGVFTTYSDVWSFGVVLWEIATLAEQPYQG-LSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISSIK---------------------------------------------------------------------------------------
31 PsiBlast_CBE 73.5843%-110 - C1 -3LW0 IGF1R_HUMAN A:[7-285] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PDEWEVA-REKITMS-R-ELGQGSFGMVYEGVAKGVVK-D-E--PETRVAIKTVNEAASMRERIE-FLNEASVMKEF-NCHHVVR----LLGVVSQGQPT-LVIMELMTRGDLKSYLRS-LRP-----------------------P--PS----LSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVA---ED--FTVKIGDFGMTR--DIYET-DYYRKG---LLPVRWMSPESLKDGVFTTYSDVWSFGVVLWEIATLAEQPYQG-LSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISSIK---------------------------------------------------------------------------------------
46 PsiBlast_CBE 73.1344%-111 - C1 -3EKK A:[10-288] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PDEWEVS-REKITLL-R-ELGQGSFGMVYEGNARDIIK-G-E--AETRVAVKTVNESASLRERIE-FLNEASVMKGF-TCHHVVR----LLGVVSKGQPT-LVVMELMAHGDLKSYLRS-LRP------EAENNP--GRP---P--P---T----LQEMIQMAAEIADGMAYLNAKKFVHRNLAARNCMVA---HD--FTVKIGDF---------------------LLPVRWMAPESLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQG-LSNEQVLKFVMDGGYLDQPDNCPERVTDLMRMCWQFNPNMRPTFLEIVNLLK---------------------------------------------------------------------------------------
29 PsiBlast_CBE 73.0743%-109 - C1 -3LW0 IGF1R_HUMAN C:[7-285] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PDEWEVA-REKITMS-R-ELGQGSFGMVYEGVAKGVVK-D-E--PETRVAIKTVNEAASMRERIE-FLNEASVMKEF-NCHHVVR----LLGVVSQGQPT-LVIMELMTRGDLKSYLRS-LRP-----------------------P--PS----LSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVA---ED--FTVKIGDFGMTR--DIYET-DYYRKG---LLPVRWMSPESLKDGVFTTYSDVWSFGVVLWEIATLAEQPYQG-LSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISSIK---------------------------------------------------------------------------------------
116 HHSearch 72.5744%-115 * C1 *4AOJ NTRK1_HUMAN A:[34-322] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CVHHIK-RRDIVLK-W-ELGEGAFGKVFLAECHNLLP-------KMLVAVKALKE-ASESARQD-FQREAELLTML-QHQHIVR----FFGVCTEGRPL-LMVFEYMRHGDLNRFLRS-HGP------D---------P---G--P--LG----LGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVG---QG--LVVKIGDFG-------------------TMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQ-LSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQRHSIKDVHARLQALAQA-PP-------------------------------------------------------------------------------
51 PsiBlast_CBE 72.1539%-113 - C1 -4AT4 A:[7-285] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VQHIK-RHNIVLK-R-ELGEGAFGKVFLAECYNLC--------KILVAVKTLKD-ASDNARKD-FHREAELLTNL-QHEHIVK----FYGVCVEGDPL-IMVFEYMKHGDLNKFLRA-HGP------DAVLMA---PP---T--E--LT----QSQMLHIAQQIAAGMVYLASQHFVHRDLATRNCLV---GEN--LLVKIGDFGMSR--DVYST-DYYRVGGHTMLPIRWMPPESIMYRKFTTESDVWSLGVVLWEIFTYGKQPWYQ-LSNNEVIECITQGRVLQRPRTCPQEVYELMLGCWQREPHMRKNIKGIHTLLQ---------------------------------------------------------------------------------------
26 PsiBlast_CBE 72.0443%-108 - C1 -3NW6 A:[10-288] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PDEWEVA-REKITMS-R-ELGQGSFGMVYEGVAKGVVK-D-E--PETRVAIKTVNEAASMRERIE-FLNEASVMKEF-NCHHVVR----LLGVVSQGQPT-LVIMELMTRGDLKSYLRS-LRP------EM------ENNPVLA--P--PS----LSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVA---ED--FTVKIGDFGMTR--DIYET-DYYRKGGKGLLPVRWMSPESLKDGVFTTYSDVWSFGVVLWEIATLAEQPYQG-LSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISSIK---------------------------------------------------------------------------------------
28 PsiBlast_CBE 72.0343%-109 - C1 -3LW0 D:[7-285] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PDEWEVA-REKITMS-R-ELGQGSFGMVYEGVAKGVVK-D-E--PETRVAIKTVNEAASMRERIE-FLNEASVMKEF-NCHHVVR----LLGVVSQGQPT-LVIMELMTRGDLKSYLRS-LRP-----------------------P--PS----LSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVA---ED--FTVKIGDFGMTR--DIYET-DYYRKG---LLPVRWMSPESLKDGVFTTYSDVWSFGVVLWEIATLAEQPYQG-LSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISSIK---------------------------------------------------------------------------------------
38 PsiBlast_CBE 71.7943%-110 - C1 -3I81 A:[10-288] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PDEWEVA-REKITMS-R-ELGQGSFGMVYEGVAKGVVK-D-E--PETRVAIKTVNEAASMRERIE-FLNEASVMKEF-NCHHVVR----LLGVVSQGQPT-LVIMELMTRGDLKSYLRS-LRP------E-------ENNPVLA--P--PS----LSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVA---ED--FTVKIGDFGMTR--DIYET-DYYR-----LLPVRWMSPESLKDGVFTTYSDVWSFGVVLWEIATLAEQPYQG-LSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISSIK---------------------------------------------------------------------------------------
50 PsiBlast_CBE 71.7339%-110 - C1 -4AT5 A:[7-285] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VQHIK-RHNIVLK-R-ELGEGAFGKVFLAECYNL---------KILVAVKTLKD-ASDNARKD-FHREAELLTNL-QHEHIVK----FYGVCVEGDPL-IMVFEYMKHGDLNKFLRA-HGP------DAVLMAEGNPP---T--E--LT----QSQMLHIAQQIAAGMVYLASQHFVHRDLATRNCLV---GEN--LLVKIGDFGMSR--DVYST-DYYRVGGHTMLPIRWMPPESIMYRKFTTESDVWSLGVVLWEIFTYGKQPWYQ-LSNNEVIECITQGRVLQRPRTCPQEVYELMLGCWQREPHMRKNIKGIHTLLQ---------------------------------------------------------------------------------------
27 PsiBlast_CBE 71.6143%-110 - C1 -3NW5 A:[10-288] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PDEWEVA-REKITMS-R-ELGQGSFGMVYEGVAKGVVK-D-E--PETRVAIKTVNEAASMRERIE-FLNEASVMKEF-NCHHVVR----LLGVVSQGQPT-LVIMELMTRGDLKSYLRS-LRP------EM------ENNPVLA--P--PS----LSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVA---ED--FTVKIGDFGMTR--DIYET-DYYRKGGKGLLPVRWMSPESLKDGVFTTYSDVWSFGVVLWEIATLAEQPYQG-LSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISSIK---------------------------------------------------------------------------------------
52 PsiBlast_CBE 71.5939%-111 - C1 -4AT3 A:[7-285] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VQHIK-RHNIVLK-R-ELGEGAFGKVFLAECYNLC--------KILVAVKTL---ASDNARKD-FHREAELLTNL-QHEHIVK----FYGVCVEGDPL-IMVFEYMKHGDLNKFLRA-HGP------DAVLMA--NPP---T--E--LT----QSQMLHIAQQIAAGMVYLASQHFVHRDLATRNCLV---GEN--LLVKIGDFGMSR----YST-DYYRVGGHTMLPIRWMPPESIMYRKFTTESDVWSLGVVLWEIFTYGKQPWYQ-LSNNEVIECITQGRVLQRPRTCPQEVYELMLGCWQREPHMRKNIKGIHTLLQ---------------------------------------------------------------------------------------
58 PsiBlast_CBE 71.5339%-114 - C1 -2I0V A:[39-329] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EKWEFPRN--------NLQFG-K-TLGAGAFGKVVEATAFGLGK-E-D--AVLKVAVKMLKSTAHADEKEA-LMSELKIMSHLGQHENIVN----LLGACTHGGPV-LVITEYCCYGDLLNFLRR-KR------------------------Q--LS----SRDLLHFSSQVAQGMAFLASKNCIHRDVAARNVLLT---NG--HVAKIGDFGLAR--DIMND-SNYIVKG-ARLPVKWMAPESIFDCVYTVQSDVWSYGILLWEIFSLGLNPYPGILVNSKFYKLVKDGYQMAQPAFAPKNIYSIMQACWALEPTHRPTFQQICSFLQEQAQE----------------------------------------------------------------------------------
43 PsiBlast_CBE 71.4544%-104 - C1 -1I44 A:[9-287] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PDEWEVS-REKITLL-R-ELGQGSFGMVYEGNARDIIK-G-E--AETRVAVKTVNESASLRERIE-FLNEASVMKGF-TCHHVVR----LLGVVSKGQPT-LVVMELMAHGDLKSYLRS-LRP------EAENNP--GRP---P--P---T----LQEMIQMAAEIADGMAYLNAKKFVHRDLAARNCMVA---HD--FTVKIGDFGMT-------------------LPVRWMAPESLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQG-LSNEQVLKFVMDGGYLDQPDNCPERVTDLMRMCWQFNPKMRPTFLEIVNLLK---------------------------------------------------------------------------------------
39 PsiBlast_CBE 71.3940%-117 - C1 -3LVP IGF1R_HUMAN A:[39-317] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PDEW-------EVA-REKITMS-R-ELGQGSFGMVYEGVAKGVVK-D-E--PETRVAIKTVNEAASMRERIE-FLNEASVMKEF-NCHHVVR----LLGVVSQGQPT-LVIMELMTRGDLKSYLRS-LRP------EM------E--PVLA--P--PS----LSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVA---ED--FTVKIGDFGMTR--DIY--------GGKGLLPVRWMSPESLKDGVFTTYSDVWSFGVVLWEIATLAEQPYQG-LSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISSIK---------------------------------------------------------------------------------------
47 PsiBlast_CBE 71.2441%-110 - C1 -4AOJ C:[35-322] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VHHIK-RRDIVLK-W-ELGEGAFGKVFLAECHNLLP---Q--DKMLVAVKALKE-ASESARQD-FQREAELLTML-QHQHIVR----FFGVCTEGRPL-LMVFEYMRHGDLNRFLRS-HGP------D-------------G--P--LG----LGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLV---GQG--LVVKIGDFGM-------------------MLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQ-LSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQRHSIKDVHARLQALAQA-PP-------------------------------------------------------------------------------
48 PsiBlast_CBE 71.2241%-111 - C1 -4AOJ NTRK1_HUMAN B:[35-324] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VHHIK-RRDIVLK-W-ELGEGAFGKVFLAECHNLLP-------KMLVAVKALKE-ASESARQD-FQREAELLTML-QHQHIVR----FFGVCTEGRPL-LMVFEYMRHGDLNRFLRS-HGP------D-------------G--P--LG----LGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLV---GQG--LVVKIGDF----------------------LPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQ-LSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQRHSIKDVHARLQALAQA-PPVY-----------------------------------------------------------------------------
25 PsiBlast_CBE 70.9843%-107 - C1 -3NW7 A:[10-288] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PDEWEVA-REKITMS-R-ELGQGSFGMVYEGVAKGVVK-D-E--PETRVAIKTVNEAASMRERIE-FLNEASVMKEF-NCHHVVR----LLGVVSQGQPT-LVIMELMTRGDLKSYLRS-LRP------EM------ENNPVLA--P--PS----LSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVA---ED--FTVKIGDFGMTR--DIYET-DYYRKG---LLPVRWMSPESLKDGVFTTYSDVWSFGVVLWEIATLAEQPYQG-LSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISSIK---------------------------------------------------------------------------------------
124 HHSearch 70.6643%-110 - C1 -3CBL A:[104-372] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VPKDKWVLN-HEDLVLG-E-QIGRGNFGEVFSGRLRA---------DNTLVAVKSCRETLPPDLKAK-FLQEARILKQY-SHPNIVR----LIGVCTQKQPI-YIVMELVQGGDFLTFLRT-EG---------------------A--R--LR----VKTLLQMVGDAAAGMEYLESKCCIHRDLAARNCLVTE---K--NVLKISDFGMSR--EEADG-VYAASGGLRQVPVKWTAPEALNYGRYSSESDVWSFGILLWETFSLGASPYPN-LSNQQTREFVEKGGRLPCPELCPDAVFRLMEQCWAYEPGQRPSFSTIYQELQSI-------------------------------------------------------------------------------------
45 PsiBlast_CBE 70.6544%-105 - C1 -3EKN A:[10-288] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PDEWEVS-REKITLL-R-ELGQGSFGMVYEGNARDIIK-G-E--AETRVAVKTVNESASLRERIE-FLNEASVMKGF-TCHHVVR----LLGVVSKGQPT-LVVMELMAHGDLKSYLRS-LRP------EAENNP--GRP---P--P---T----LQEMIQMAAEIADGMAYLNAKKFVHRNLAARNCMVA---HD--FTVKIGDFGMTR--DIYET-DYYRKG---LLPVRWMAPESLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQG-LSNEQVLKFVMDGGYLDQPDNCPERVTDLMRMCWQFNPNMRPTFLEIVNLLK---------------------------------------------------------------------------------------
37 PsiBlast_CBE 70.4843%-106 - C1 -1JQH IGF1R_HUMAN B:[11-289] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PDEWEVA-REKITMS-R-ELGQGSFGMVYEGVAKGVVK-D-E--PETRVAIKTVNEAASMRERIE-FLNEASVMKEF-NCHHVVR----LLGVVSQGQPT-LVIMELMTRGDLKSYLRS-LRP-----------------------P--PS----LSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVA---ED--FTVKIGDFGMT----------YYRKGGKGLLPVRWMSPESLKDGVFTTYSDVWSFGVVLWEIATLAEQPYQG-LSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISSIK---------------------------------------------------------------------------------------
42 PsiBlast_CBE 70.0644%-100 - C1 -3ETA INSR_HUMAN A:[12-286] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EVS-REKITLL-R-ELGQGSFGMVYEGNARDIIK-G-E--AETRVAVKTVNESASLRERIE-FLNEASVMKGF-TCHHVVR----LLGVVSKGQPT-LVVMELMAHGDLKSYLRS-LRP------EAENNP--GRP---P--P---T----LQEMIQMAAEIADGMAYLNAKKFVHRDLAARNCMVA---HD--FTVKIGDFGMTR--DIYET-DYYRKG-KGLLPVRWMAPESLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQG-LSNEQVLKFVMDGGYLDQPDNCPERVTDLMRMCWQFNPKMRPTFLEIVNLLK---------------------------------------------------------------------------------------
79 PsiBlast_CBE 69.6236%-107 - C1 -1MQB B:[35-316] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LKFTTEIH-PSCVTRQ-K-VIGAGEFGEVYKGMLKT------K--E-VPVAIKTLKAGYTEKQRVD-FLGEAGIMGQF-SHHNIIR----LEGVISKYKPM-MIITEYMENGALDKFLRE-KD---------------GEF---S--V--L-------QLVGMLRGIAAGMKYLANMNYVHRDLAARNILVNS---N--LVCKVSDFGLSRVL-------------K--IPIRWTAPEAISYRKFTSASDVWSFGIVMWEVMTYGERPYWE-LSNHEVMKAINDGFRLPTPMDCPSAIYQLMMQCWQQERARRPKFADIVSILDKLIRA-PDSLKT---------------------------------------------------------------------------
24 PsiBlast_CBE 69.6149%-114 - C1 -3ZBF ? A:[34-306] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KLTLR-L-LLGS---GEVYEGTAVDILGVG-S--GEIKVAVKTLKKGSTDQEKIE-FLKEAHLMSKF-NHPNILK----QLGVCLLNEPQ-YIILELMEGGDLLTYLRK-ARM------AT------FYG---P--L--LT----LVDLVDLCVDISKGCVYLERMHFIHRDLAARNCLVSVKDYTSPRIVKIGDFGLAR--DIY-------------LPVRWMAPESLMDGIFTTQSDVWSFGILIWEILTLGHQPYPA-HSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTFHRIQDQLQ---------------------------------------------------------------------------------------
76 PsiBlast_CBE 69.2337%-112 - C1 -4F64 FGFR1_HUMAN A:[16-299] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELP-RDRLVLG-K-PL-----GQVVLAEAIGL----PN--RVTKVAVKMLKSDATEKDLSD-LISEMEMMKMIGKHKNIIN----LLGACTQDGPL-YVIVEYASKGNLREYLQA-RRPP--------------------EEQ--LS----SKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVT---ED--NVMKIADFGLAR--DIHHI-DYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPG-VPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLD---------------------------------------------------------------------------------------
57 PsiBlast_CBE 69.0739%-105 - C1 -2I0Y A:[39-329] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EKWEFPRN--------NLQFG-K-TLGAGAFGKVVEATAFGLGK-E-D--AVLKVAVKMLKSTAHADEKEA-LMSELKIMSHLGQHENIVN----LLGACTHGGPV-LVITEYCCYGDLLNFLRR-KR------------------------Q--LS----SRDLLHFSSQVAQGMAFLASKNCIHRDVAARNVLLT---NG--HVAKIGDFGLAR--DIMND-SNYIVKG-ARLPVKWMAPESIFDCVYTVQSDVWSYGILLWEIFSLGLNPYPGILVNSKFYKLVKDGYQMAQPAFAPKNIYSIMQACWALEPTHRPTFQQICSFLQEQAQE----------------------------------------------------------------------------------
32 PsiBlast_CBE 69.0643%-106 - C1 -2OJ9 A:[10-288] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PDEWEVA-REKITMS-R-ELGQGSFGMVYEGVAKGVVK-D-E--PETRVAIKTVNEAASMRERIE-FLNEASVMKEF-NCHHVVR----LLGVVSQGQPT-LVIMELMTRGDLKSYLRS-LRP------E----------------P--PS----LSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVA---ED--FTVKIGDFGMTR--DIYET-DYYRKGGKGLLPVRWMSPESLKDGVFTTYSDVWSFGVVLWEIATLAEQPYQG-LSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISSIK---------------------------------------------------------------------------------------
80 PsiBlast_CBE 68.7836%-106 - C1 -1MQB EPHA2_HUMAN A:[38-317] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TTEIH-PSCVTRQ-K-VIGAGEFGEVYKGMLKT----K-K--E-VPVAIKTLKAGYTEKQRVD-FLGEAGIMGQF-SHHNIIR----LEGVISKYKPM-MIITEYMENGALDKFLRE-KD---------------GEF---S--V--L-------QLVGMLRGIAAGMKYLANMNYVHRDLAARNILVNS---N--LVCKVSDFGL-----------------K--IPIRWTAPEAISYRKFTSASDVWSFGIVMWEVMTYGERPYWE-LSNHEVMKAINDGFRLPTPMDCPSAIYQLMMQCWQQERARRPKFADIVSILDKLIRA-PDSLKTL--------------------------------------------------------------------------
95 PsiBlast_CBE 68.1638%-108 - C1 -2I1M A:[39-327] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EKWEFPRN--------NLQFG-K-TLGAGAFGKVVEATAFGLGK-E-D--AVLKVAVKMLKSTAHADEKEA-LMSELKIMSHLGQHENIVN----LLGACTHGGPV-LVITEYCCYGDLLNFLRRKSRV------LE------TD------------STASTRDLLHFSSQVAQGMAFLASKNCIHRDVAARNVLLT---NG--HVAKIGDFGLAR--DIMND-SNYIVKGNARLPVKWMAPESIFDCVYTVQSDVWSYGILLWEIFSLGLNPYPGILVNSKFYKLVKDGYQMAQPAFAPKNIYSIMQACWALEPTHRPTFQQICSFLQEQAQE----------------------------------------------------------------------------------
36 PsiBlast_CBE 68.1443%-111 - C1 -3QQU IGF1R_HUMAN A:[6-282] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EWEVA-REKITMS-R-ELGQGSFGMVYEGVAKGVVK-D-E--PETRVAIKTVNEAASMRERIE-FLNEASVMKEF-NCHHVVR----LLGVVSQGQPT-LVIMELMTRGDLKSYLRS-LR------------------------P--PS----LSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVA---ED--FTVKIGDFGMTR--DIYET-DYYRKGGKGLLPVRWMSPESLKDGVFTTYSDVWSFGVVLWEIATLAEQPYQG-LSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISSIK---------------------------------------------------------------------------------------
75 PsiBlast_CBE 67.9737%-113 - C1 -4F64 B:[16-299] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELP-RDRLVLG-K-PLGEGAFGQVVLAEAIGL----PN--RVTKVAVKMLKSDATEKDLSD-LISEMEMMKMIGKHKNIIN----LLGACTQDGPL-YVIVEYASKGNLREYLQA-RR------------------------Q--LS----SKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVT---ED--NVMKIADFGLA---------DYYKK---GRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPG-VPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLD---------------------------------------------------------------------------------------