@TOME V2.3
(Nov 2016)

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Alignment:

3D Common Core:

Structural Clustering:

Modeller Result :

Complexes Modeling
Templates Information:
Sequence & Result Tab:

Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : MK10_HUMAN: (2013-07-23 )
MSLHFLYYCSEPTLDVKIAFCQGFDKQVDVSYIAKHYNMSKSKVDNQFYSVEVGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRNYVENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYINVWYDPAEVEAPPPQIYDKQLDEREHTIEEWKELIYKEVMNSEEKTKNGVVKGQPSPSGAAVNSSESLPPSSSVNDISSMSTDQTLASDTDSSLEASAGPLGCCR

Atome Classification :

(84 SA) .........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150......-.--160........170.......180.......190.......200.......210....-----...220.......230.....-..-240.......250.......260.......270.......280.......--290.-.-......300.......310.......320.......330.......340.......350.......360....-...---370.......380.......390.......400.......410.......420.......430.......440.......450.......460..
(Atome) (Ident) (Tito) (Num) (Ligand) (Uniprot) MSLHFLYYCSEPTLDVKIAFCQGFDKQVDVSYIAKHYNMSKSKVDNQFYSVEVGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQ-M--E-LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGT-----SFMMTPYVVTRYYRAPEVILG-MG-YKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKK--LQ-P-T-VRNYVENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYINVWYDPA-EVE---APPPQIYDKQLDEREHTIEEWKELIYKEVMNSEEKTKNGVVKGQPSPSGAAVNSSESLPPSSSVNDISSMSTDQTLASDTDSSLEASAGPLGCCR
21 PsiBlast_CBE 98.12100%-139 - C2 -3V6S MK10_HUMAN B:[7-363] --------------------------------------------DNQFYSVEVGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQ-M--E-LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLA------------------VTRYYRAPEVILG-MG-YKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKK--LQ-P-T-VRNYVENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYINVWYDPA-EVE---APPPQI---QLDEREHTIEEWKELIYKEVMNS---------------------------------------------------------------
5 PsiBlast_PDB 96.67100%-143 - C2 -2O2U MK10_HUMAN A:[8-362] ---------------------------------------------NQFYSVEVGDSTFTVLKRYQNLKPIGSG--GIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQ-M--E-LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLA------------------VTRYYRAPEVILG-MG-YKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKK--LQ-P-T-VRNYVENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYINVWY-------------------------HTIEEWKELIYKEVMN----------------------------------------------------------------
10 PsiBlast_PDB 95.73100%-131 - C2 -2OK1 MK10_HUMAN A:[9-363] ---------------------------------------------NQFYSVEVGDSTFTVLKRYQNLKPIG--AQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQ-M--E-LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLA------------------VTRYYRAPEVILG-MG-YKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKK--LQ-P-T-VRNYVENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYINVWYDPA-EVE---APPP-------DEREHTIEEWKELIYKEVMN----------------------------------------------------------------
8 PsiBlast_PDB 95.46100%-134 - C2 -2WAJ MK10_HUMAN A:[8-362] ---------------------------------------------NQFYSVEVGDSTFTVLKRYQNLKPIGSG--GIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQ-M--E-LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLAR---T-----SFMMTPYVVTRYYRAPEVILG-MG-YKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKK--LQ-P-T-VRNYVENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYINVWYDPA-EVE---APPPQ--DKQLDEREHTIEEWKELIYKEVMN----------------------------------------------------------------
20 PsiBlast_PDB 95.32100%-133 - C2 -2EXC MK10_HUMAN X:[1-356] --------------------------------------------DNQFYSVEVGDSTFTVLKRYQNLKPIGS---GIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQ-M--E-LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLA------------------VTRYYRAPEVILG-MG-YKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKK--LQ-P-T-VRNYVENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYINVWYDPA-EVE---APPP-----QLDEREHTIEEWKELIYKEVMN----------------------------------------------------------------
18 PsiBlast_PDB 95.25100%-131 - C2 -1PMU MK10_HUMAN A:[8-363] --------------------------------------------DNQFYSVEVGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQ-M--E-LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLAR-------------TPYVVTRYYRAPEVILG-MG-YKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKK--LQ-P-T-VRNYVENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYINVWYDPA-EVE---APPPQ------DEREHTIEEWKELIYKEVMN----------------------------------------------------------------
12 PsiBlast_PDB 95.19100%-134 - C2 -3CGF MK10_HUMAN A:[8-363] --------------------------------------------DNQFYSVEVGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQ-M--E-LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLA----------SFMMTPYVVTRYYRAPEVILG-MG-YKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKK--LQ-P-T-VRNYVENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYINVWYDPA-EVE---APPP-----QLDEREHTIEEWKELIYKEVMN----------------------------------------------------------------
17 PsiBlast_PDB 95.09100%-134 - C2 -1PMN MK10_HUMAN A:[8-363] --------------------------------------------DNQFYSVEVGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQ-M--E-LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLA----------SFMMTPYVVTRYYRAPEVILG-MG-YKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKK--LQ-P-T-VRNYVENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYINVWYDPA-EVE---AP-------QLDEREHTIEEWKELIYKEVMN----------------------------------------------------------------
4 PsiBlast_PDB 94.95100%-142 - C2 -2O0U MK10_HUMAN A:[8-362] ---------------------------------------------NQFYSVEVGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQ-M--E-LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLAR----------FMMTPYVVTRYYRAPEVILG-MG-YKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKK--LQ-P-T-VRNYVENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYINVWY-----------------------REHTIEEWKELIYKEVMN----------------------------------------------------------------
1 PsiBlast_PDB 94.72100%-131 - C2 -3TTJ MK10_HUMAN A:[46-400] ---------------------------------------------NQFYSVEV--STFTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQ-M--E-LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLA----------SFMM----VTRYYRAPEVILG-MG-YKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKK--LQ-P-T-VRNYVENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYINVWYDPA-EVE---APP-----------EHTIEEWKELIYKEVMN----------------------------------------------------------------
7 PsiBlast_PDB 94.53100%-132 - C2 -2ZDU MK10_HUMAN A:[8-362] ---------------------------------------------NQFYSVEVGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQ-M--E-LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLA------------------VTRYYRAPEVILG-MG-YKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKK--LQ-P-T-VRNYVENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYINVWYDPA-EVE---A------------REHTIEEWKELIYKEVMN----------------------------------------------------------------
6 PsiBlast_PDB 94.30100%-132 - C2 -2ZDT MK10_HUMAN A:[7-362] --------------------------------------------DNQFYSVEVGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQ-M--E-LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLA----------SFMMTPYVVTRYYRAPEVILG-MG-YKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKK--LQ-P-T-VRNYVENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYINVWYDPA-EVE---APPP---------REHTIEEWKELIYKEVMN----------------------------------------------------------------
19 PsiBlast_PDB 94.18100%-137 - C2 -3OXI MK10_HUMAN A:[7-361] ---------------------------------------------NQFYSVEVGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQ-M--E-LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFG--------------------VTRYYRAPEVILG-MG-YKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKK--LQ-P-T-VRNYVENRPKYAGLTFPKLFPDSLFP----HNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYINVWYDPA-EV-----------------REHTIEEWKELIYKEVMN----------------------------------------------------------------
3 PsiBlast_PDB 94.16100%-132 - C2 -1JNK MK10_HUMAN A:[45-400] --------------------------------------------DNQFYSVEVGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQ-M--E-LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLA----------SFMMTPYVVTRYYRAPEVILG-MG-YKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKK--LQ-P-T-VRNYVENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYINVWYDPA-EVE---APPP-----QLDEREHTIEEWKELIYKEVMN----------------------------------------------------------------
2 PsiBlast_PDB 94.08100%-134 - C2 -3TTI MK10_HUMAN A:[46-400] ---------------------------------------------NQFYSVEVGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQ-M--E-LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLA----------SFMMTPYVVTRYYRAPEVILG-MG-YKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKK--LQ-P-T-VRNYVENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYINVWYDPA-EVE---APPP---------REHTIEEWKELIYKEVMN----------------------------------------------------------------
16 PsiBlast_PDB 94.03100%-131 - C2 -3PTG MK10_HUMAN A:[8-363] ---------------------------------------------NQFYSVEVGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQ-M--E-LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLA------------------VTRYYRAPEVILG-MG-YKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKK--LQ-P-T-VRNYVENRPKYAGLTFPKLFPDSLFPA---HNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYINVWYDPA-EVE---APPPQIYDKQLDEREHTIEEWKELIYKEVMNS---------------------------------------------------------------
52 PsiBlast_CBE 93.6985%-138 - C2 -3E7O MK09_HUMAN A:[7-359] ----------------------------------------------QFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH-M--E-LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAST-----NFMMTPYVVTRYYRAPEVILG-MG-YKENVDIWSVGCIMGELVKGSVIFQGTDHIDQWNKVIEQLGTPSAEFMAA--LQ-P-T-VRNYVENRPAYPGIAFEELFPDWIFPSE--RDKIKTSQARDLLSKMLVIDPDKRISVDEALRHPYITVWYDPA-EAE---APPPQI---------HAIEEWKELIYKEVM-----------------------------------------------------------------
41 PsiBlast_CBE 93.3791%-141 - C2 -1UKI MK08_HUMAN A:[9-362] ----------------------------------------------NFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ-M--E-LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLAR------------------TRYYRAPEVILG-MG-YKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQLGTPCPEFMKK--LQ-P-T-VRTYVENRPKYAGYSFEKLFPDVLFP-----NKLKASQARDLLSKMLVIDASKRISVDEALQHPYINVWYDPS-EAE---APPPKI---------HTIEEWKELIYKEVMD----------------------------------------------------------------
28 PsiBlast_CBE 93.2392%-132 - C2 -4AWI MK08_HUMAN A:[13-369] ---------------------------------------------NNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ-M--E-LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLA----------SFMMTPYVVTRYYRAPEVILG-MG-YKENVDLWSVGCIMGEMVCHKILFPGRDYIDQWNKVIEQLGTPCPEFMKK--LQ-P-T-VRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSKMLVIDASKRISVDEALQHPYINVWYDPS-EAE---APPPKIPDKQLDEREHTIEEWKELIYKEVMDLE--------------------------------------------------------------
11 PsiBlast_PDB 92.50100%-135 - C2 -2P33 MK10_HUMAN A:[8-363] --------------------------------------------DNQFYSVEVGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQ-M--E-LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLA----------SFMMTPYVVTRYYRAPEVILG-MG-YKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKK--LQ-P-T-VRNYVENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYINVWY-----------------------REHTIEEWKELIYKEVMN----------------------------------------------------------------
36 PsiBlast_CBE 91.9992%-123 - C2 -2H96 MK08_HUMAN A:[7-364] --------------------------------------------DNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ-M--E-LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGT-----SFMMEPEVVTRYYRAPEVILG-MG-YKENVDLWSVGCIMGEMVCHKILFPGRDYIDQWNKVIEQLGTPCPEFMKK--LQ-P-T-VRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSKMLVIDASKRISVDEALQHPYINVWYDPS-EAE---APPPKIPDKQLDEREHTIEEWKELIYKEVMDLE--------------------------------------------------------------
27 PsiBlast_CBE 91.7590%-128 - C2 -2XS0 MK08_HUMAN A:[8-367] -------------------------------------------RDNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ-M--E-LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLA-------------------TRYYRAPEVILG-MG-YKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQLGTPCPEFMKK--LQ-P-T-VRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSKMLVIDASKRISVDEALQHPYINVWYDPS-EAE---APPPKIPDKQLDEREHTIEEWKELIYKEVMDLEE-------------------------------------------------------------
13 PsiBlast_PDB 91.73100%-134 - C2 -3CGO MK10_HUMAN A:[8-363] --------------------------------------------DNQFYSVEVGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQ-M--E-LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLA----------SFMMTPYVVTRYYRAPEVILG-MG-YKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKK--LQ-P-T-VRNYVENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYINVWY-----------------------REHTIEEWKELIYKEVMN----------------------------------------------------------------
51 PsiBlast_CBE 91.7186%-126 - C2 -3NPC MK09_HUMAN A:[7-363] --------------------------------------------DNQFYSVEVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH-M--E-LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACT-----NFMMTPYVVTRYYRAPEVILG-MG-YAANVDIWSVGCIMGELVKGCVIFQGTDHIDQWNKVIEQLGTPSAEFMAA--LQ-P-T-VRNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSKMLVIDPDKRISVDEALRHPYITVWYDPA-EAE---APPPQIYDAQLEEREHAIEEWKELIYKEVMDW---------------------------------------------------------------
44 PsiBlast_CBE 91.0191%-127 - C2 -3V3V MK08_HUMAN A:[7-362] --------------------------------------------DNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ-M--E-LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGT-----S----PEVVTRYYRAPEVILG-MG-YKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQLGTPCPEFMKK--LQ-P-T-VRTYVENRPKYAGYSFEKLFPDVLFPADSEH--LKASQARDLLSKMLVIDASKRISVDEALQHPYINVWYDPS-EAE---APPPKIPDKQLDEREHTIEEWKELIYKEVMD----------------------------------------------------------------
34 PsiBlast_CBE 90.6692%-122 - C2 -2NO3 MK08_HUMAN A:[8-364] ---------------------------------------------NNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ-M--E-LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGT-----SFMMEPEVVTRYYRAPEVILG-MG-YKENVDLWSVGCIMGEMVCHKILFPGRDYIDQWNKVIEQLGTPCPEFMKK--LQ-P-T-VRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSKMLVIDASKRISVDEALQHPYINVWYDPS-EAE---APPPKIPDKQLDEREHTIEEWKELIYKEVMDLE--------------------------------------------------------------
50 PsiBlast_CBE 90.2286%-125 - C2 -3NPC MK09_HUMAN B:[8-363] ---------------------------------------------NQFYSVEVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH-M--E-LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACT-----NFMMTPYVVTRYYRAPEVILG-MG-YAANVDIWSVGCIMGELVKGCVIFQGTDHIDQWNKVIEQLGTPSAEFMAA--LQ-P-T-VRNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSKMLVIDPDKRISVDEALRHPYITVWYDPA-EAE---APPPQIYDAQLEEREHAIEEWKELIYKEVMDW---------------------------------------------------------------
38 PsiBlast_CBE 89.6292%-122 - C2 -2GMX MK08_HUMAN A:[8-364] ---------------------------------------------NNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ-M--E-LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGT-----SFMMEPEVVTRYYRAPEVILG-MG-YKENVDLWSVGCIMGEMVCHKILFPGRDYIDQWNKVIEQLGTPCPEFMKK--LQ-P-T-VRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSKMLVIDASKRISVDEALQHPYINVWYDPS-EAE---APPPKIPDKQLDEREHTIEEWKELIYKEVMDLE--------------------------------------------------------------
45 PsiBlast_CBE 89.5390%-115 - C2 -3VUH MK08_HUMAN A:[7-364] --------------------------------------------DNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLSQVIQ-M--E-LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDATLKILDFGLARTAGT-----S---TPYVVTRYYRAPEVILG-MG-YKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQLGTPSPEFMKK--LQ-P-T-VRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSKMLVIDASKRISVDEALQHPYINVWYDPS-EAE---APPPKIPDKQLDEREHTIEEWKELIYKEVMDLE--------------------------------------------------------------
33 PsiBlast_CBE 89.4992%-121 - C2 -2NO3 MK08_HUMAN B:[7-363] --------------------------------------------DNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ-M--E-LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGT-----SFMMEPEVVTRYYRAPEVILG-MG-YKENVDLWSVGCIMGEMVCHKILFPGRDYIDQWNKVIEQLGTPCPEFMKK--LQ-P-T-VRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSKMLVIDASKRISVDEALQHPYINVWYDPS-EAE---APPPKIPDKQLDEREHTIEEWKELIYKEVMDL---------------------------------------------------------------
40 PsiBlast_CBE 88.6392%-121 - C2 -2G01 MK08_HUMAN A:[10-364] -----------------------------------------------FYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ-M--E-LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGT-----SFMMEPEVVTRYYRAPEVILG-MG-YKENVDLWSVGCIMGEMVCHKILFPGRDYIDQWNKVIEQLGTPCPEFMKK--LQ-P-T-VRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSKMLVIDASKRISVDEALQHPYINVWYDPS-EAE---APPPKIPDKQLDEREHTIEEWKELIYKEVMDLE--------------------------------------------------------------
39 PsiBlast_CBE 88.2992%-118 - C2 -2G01 MK08_HUMAN B:[9-364] ----------------------------------------------NFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ-M--E-LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGT-----SFMMEPEVVTRYYRAPEVILG-MG-YKENVDLWSVGCIMGEMVCHKILFPGRDYIDQWNKVIEQLGTPCPEFMKK--LQ-P-T-VRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSKMLVIDASKRISVDEALQHPYINVWYDPS-EAE---APPPKIPDKQLDEREHTIEEWKELIYKEVMDLE--------------------------------------------------------------
85 PsiBlast_CBE 82.5347%-129 - C2 -2RG6 MK14_HUMAN A:[10-353] -----------------------------------------ER--PTFYRQELNKTIWEVPERYQNLSPVG----GSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ--K-LTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLAR-----------------ATRWYRAPEIMLNWMH-YNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKK--IS-SES-ARNYIQSLTQMPKMNFANVFIGA--------NPL----AVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPD-DEP---VADP--YDQSFESRDLLIDEWKSLTYDEVIS----------------------------------------------------------------
102 PsiBlast_CBE 82.2648%-132 - C2 -3FSF MK14_HUMAN A:[20-359] -----------------------------------------------FYRQELNKTIWEVPERYQNLSPVGS-----VCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ--K-LTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFG-----HT-----DDEMTGYVATRWYRAPEIMLNWMH-YNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKK--IS-SES-ARNYIQSLTQMPKMNFANVFIGA--------NPL----AVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPD-DEP---VADP--YDQSFESRDLLIDEWKSLTYDEVIS----------------------------------------------------------------
76 PsiBlast_CBE 81.9747%-128 - C2 -3NWW MK14_HUMAN A:[11-353] ------------------------------------------R--PTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ--K-LTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLAR--HT---------------RWYRAPEIMLNWMH-YNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKK--IS-SES-ARNYIQSLTQMPKMNFANVFIGA--------NPL----AVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPD-DEP---VADP--YDQSFESRDLLIDEWKSLTYDEVIS----------------------------------------------------------------
82 PsiBlast_CBE 81.6747%-126 - C2 -3BX5 MK14_HUMAN A:[11-353] ------------------------------------------R--PTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ--K-LTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLAR--HT---------------RWYRAPEIMLNWMH-YNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKK--IS-SES-ARNYIQSLTQMPKMNFANVFIGA--------NPL----AVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPD-DEP---VADP--YDQSFESRDLLIDEWKSLTYDEVIS----------------------------------------------------------------
75 PsiBlast_CBE 81.2847%-128 - C2 -3S4Q MK14_HUMAN A:[10-353] -----------------------------------------ER--PTFYRQELNKTIWEVPERYQNLSPVGS-----VCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIV--Q--K-LTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLA------------------ATRWYRAPEIM------YNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKK--IS-SES-ARNYIQSLTQMPKMNFANVFIGA--------NPL----AVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPD-DEP---VADP--YDQSFESRDLLIDEWKSLTYDEVIS----------------------------------------------------------------
84 PsiBlast_CBE 81.2347%-123 - C2 -3BV2 MK14_HUMAN A:[11-353] ------------------------------------------R--PTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ--K-LTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLAR-----------------ATRWYRAPEIMLNWMH-YNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKK--IS-SES-ARNYIQSLTQMPKMNFANVFIGA--------NPL----AVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPD-DEP---VADP--YDQSFESRDLLIDEWKSLTYDEVIS----------------------------------------------------------------
114 PsiBlast_CBE 80.6848%-124 - C2 -3FKL MK14_HUMAN A:[20-359] -----------------------------------------------FYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ--K-LTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLA------------EMTGYVATRWYRAPEIMLNWMH-YNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKK--IS-SES-ARNYIQSLTQMPKMNFANVFIGA--------NPL----AVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPD-DEP---VADP--YDQSFESRDLLIDEWKSLTYDEVIS----------------------------------------------------------------
87 PsiBlast_CBE 80.4847%-131 - C2 -2QD9 MK14_HUMAN A:[11-353] ------------------------------------------R--PTFYRQELNKTIWEVPERYQNLSPVG--AYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVK------LTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLAR--------------------WYRAPEIMLNWMH-YNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKK--IS-SES-ARNYIQSLTQMPKMNFANVFIGA--------NPL----AVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPD-DEP---VADP--YDQSFESRDLLIDEWKSLTYDEVIS----------------------------------------------------------------
60 PsiBlast_CBE 80.2847%-132 - C2 -3P79 MK14_MOUSE A:[11-353] ------------------------------------------R--PTFYRQELNKTIWEVPERYQNLSPVGS---GSVCAAFDTKTGHRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ--K-LTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFG--------------------ATRWYRAPEIMLNWMH-YNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKK--IS-SES-ARNYIQSLAQMPKMNFANVFIGA--------NPL----AVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPD-DEP---VADP--YDQSFESRDLLIDEWKSLTYDEVIS----------------------------------------------------------------
58 PsiBlast_CBE 80.2647%-130 - C2 -3P7B MK14_MOUSE A:[11-353] ------------------------------------------R--PTFYRQELNKTIWEVPERYQNLSPVGS---GSVCAAFDTKTGHRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ--K-LTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFG--------------------ATRWYRAPEIMLNWMH-YNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKK--IS-SES-ARNYIQSLAQMPKMNFANVFIGA--------NPL----AVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPD-DEP---VADP--YDQSFESRDLLIDEWKSLTYDEVIS----------------------------------------------------------------
80 PsiBlast_CBE 80.1847%-121 - C2 -3MVL MK14_HUMAN A:[11-353] ------------------------------------------R--PTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ--K-LTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLAR--HT---------------RWYRAPEIMLNWMH-YNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKK--IS-SES-ARNYIQSLTQMPKMNFANVFIGA--------NPL----AVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPD-DEP---VADP--YDQSFESRDLLIDEWKSLTYDEVIS----------------------------------------------------------------
78 PsiBlast_CBE 80.1147%-128 - C2 -3MVM MK14_HUMAN A:[10-353] -----------------------------------------ER--PTFYRQELNKTIWEVPERYQNLSPVGS-----VCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ--K-LTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLAR--HT--------------TRWYRAPEIMLNWMH-YNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKK--IS-SES-ARNYIQSLTQMPKMNFANVFIGA--------NPL----AVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPD-DEP---VADP--YDQSFESRDLLIDEWKSLTYDEVIS----------------------------------------------------------------
61 PsiBlast_CBE 80.1147%-132 - C2 -3P78 MK14_MOUSE A:[11-353] ------------------------------------------R--PTFYRQELNKTIWEVPERYQNLSPVGS---GSVCAAFDTKTGHRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ--K-LTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFG--------------------ATRWYRAPEIMLNWMH-YNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKK--IS-SES-ARNYIQSLAQMPKMNFANVFIGA--------NPL----AVDLLEKMLVLDSDKRITAAQALAHAYFAQYHDPD-DEP---VADP--YDQSFESRDLLIDEWKSLTYDEVIS----------------------------------------------------------------