@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : MKNK2_HUMAN: (2013-07-23 )
MVQKKPAELQGFHRSFKGQNPFELAFSLDQPDHGDSDFGLQCSARPDMPASQPIDIPDAKKRGKKKKRGRATDSFSGRFEDVYQLQEDVLGEGAHARVQTCINLITSQEYAVKIIEKQPGHIRSRVFREVEMLYQCQGHRNVLELIEFFEEEDRFYLVFEKMRGGSILSHIHKRRHFNELEASVVVQDVASALDFLHNKGIAHRDLKPENILCEHPNQVSPVKICDFDLGSGIKLNGDCSPISTPELLTPCGSAEYMAPEVVEAFSEEASIYDKRCDLWSLGVILYILLSGYPPFVGRCGSDCGWDRGEACPACQNMLFESIQEGKYEFPDKDWAHISCAAKDLISKLLVRDAKQRLSAAQVLQHPWVQGCAPENTLPTPMVLQRNSCAKDLTSFAAEAIAMNRQLAQHDEDLAEEEAAGQGQPVLVRATSRCLQLSPPSQSKLAQRRQRASLSSAPVVLVGDHA
Atome Classification :
(31 SA)
.........10........20........30........40........50........60........70........80........90........100.......110....--------...120.--.---.....130.......140.......150.......160.......170....----...180.......190.......200.......210-.......220.......230.......240.......250.......260.-......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370--....-...380--.--..-......390.......400.......410.......420.......430.......440.......450.......460...
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MVQKKPAELQGFHRSFKGQNPFELAFSLDQPDHGDSDFGLQCSARPDMPASQPIDIPDAKKRGKKKKRGRATDSFSGRFEDVYQLQEDVLGEGAHARVQTCINLITSQEYAVKIIE--------KQPGHIR--S---RVFREVEMLYQCQGHRNVLELIEFFEEEDRFYLVFEKMRGGSILSHIHKRRH----FNELEASVVVQDVASALDFLHNKGIAHRDLKPENIL-CEHPNQVSPVKICDFDLGSGIKLNGDCSPISTPELLTPCGSAEYMAPEVVE-AFSEEASIYDKRCDLWSLGVILYILLSGYPPFVGRCGSDCGWDRGEACPACQNMLFESIQEGKYEFPDKDWAHISCAAKDLISKLLVRDAKQRLSAAQVLQHPWVQGCA--PENT-LPTP----M--VL-QRNSCAKDLTSFAAEAIAMNRQLAQHDEDLAEEEAAGQGQPVLVRATSRCLQLSPPSQSKLAQRRQRASLSSAPVVLVGDHA
3
PsiBlast_PDB
93.05
99%
-132
- C1 -
2HW7
1
MKNK2_HUMAN
A:
[2-302]
----------------------------------------------------------------------
S
T
D
S
F
S
G
R
F
E
D
V
Y
Q
L
Q
E
D
V
L
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E
G
A
H
A
R
V
Q
T
C
I
N
L
I
T
S
Q
E
Y
A
V
K
I
I
E
--------
K
Q
P
G
H
I
R
--
S
---
R
V
F
R
E
V
E
M
L
Y
Q
C
Q
G
H
R
N
V
L
E
L
I
E
F
F
E
E
E
D
R
F
Y
L
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F
E
K
M
R
G
G
S
I
L
S
H
I
H
K
R
R
H
----
F
N
E
L
E
A
S
V
V
V
Q
D
V
A
S
A
L
D
F
L
H
N
K
G
I
A
H
R
D
L
K
P
E
N
I
L
-
C
E
H
P
N
Q
V
S
P
V
K
I
C
D
F
G
-----------------------
G
S
A
E
Y
M
A
P
E
V
V
E
-
A
F
S
E
E
A
S
I
Y
D
K
R
C
D
L
W
S
L
G
V
I
L
Y
I
L
L
S
G
Y
P
P
F
V
G
R
C
---
C
G
-----
A
C
P
A
C
Q
N
M
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Q
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K
Y
E
F
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A
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A
A
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D
A
K
Q
R
L
S
A
A
Q
V
L
Q
H
P
W
V
Q
G
C
--------------------------------------------------------------------------------------------------------
48
PsiBlast_CBE
65.84
36%
-114
- C1 -
3MFR
1
CSKP_HUMAN
A:
[22-291]
------------------------------------------------------------------------------
F
E
D
V
Y
E
L
C
E
-
V
I
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K
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A
F
S
V
V
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C
I
N
R
E
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Q
Q
F
A
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V
A
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T
---
S
S
P
G
L
S
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--
E
---
D
L
K
R
E
A
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-
H
P
H
I
V
E
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L
E
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Y
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M
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Y
M
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E
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E
A
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A
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I
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E
A
L
R
Y
C
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D
N
N
I
I
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R
D
V
K
P
E
N
V
L
-
L
A
S
K
E
N
S
A
P
V
K
L
G
D
F
--
G
V
A
I
Q
L
-
G
E
S
G
L
V
A
G
G
R
V
G
T
P
----
H
F
M
A
P
E
V
V
K
-
R
-----
E
P
Y
G
K
P
V
D
V
W
G
C
G
V
I
L
F
I
L
L
S
G
C
L
P
F
Y
G
----------------
T
K
E
R
L
F
E
G
I
I
K
G
K
Y
K
M
N
P
R
Q
W
S
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I
S
E
S
A
K
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L
V
R
R
M
L
M
L
D
P
A
E
R
I
T
V
Y
E
A
L
N
H
P
W
L
K
----------------------------------------------------------------------------------------------------------
47
PsiBlast_CBE
65.03
36%
-114
- C1 -
3MFS
1
CSKP_HUMAN
A:
[22-291]
------------------------------------------------------------------------------
F
E
D
V
Y
E
L
C
E
-
V
I
G
K
G
A
F
S
V
V
R
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C
I
N
R
E
T
G
Q
Q
F
A
V
K
I
V
D
V
A
K
F
T
---
S
S
P
G
L
S
T
--
E
---
D
L
K
R
E
A
S
I
C
H
M
L
K
-
H
P
H
I
V
E
L
L
E
T
Y
S
S
D
G
M
L
Y
M
V
F
E
F
M
D
G
A
D
L
C
F
E
I
V
K
R
A
D
A
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F
V
Y
S
E
A
V
A
S
H
Y
M
R
Q
I
L
E
A
L
R
Y
C
H
D
N
N
I
I
H
R
D
V
K
P
E
N
V
L
-
L
A
S
K
E
N
S
A
P
V
K
L
G
D
F
--
G
V
A
I
Q
L
-
G
E
S
G
L
V
A
G
G
R
V
G
T
P
----
H
F
M
A
P
E
V
V
K
-
R
-----
E
P
Y
G
K
P
V
D
V
W
G
C
G
V
I
L
F
I
L
L
S
G
C
L
P
F
Y
G
----------------
T
K
E
R
L
F
E
G
I
I
K
G
K
Y
K
M
N
P
R
Q
W
S
H
I
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E
S
A
K
D
L
V
R
R
M
L
M
L
D
P
A
E
R
I
T
V
Y
E
A
L
N
H
P
W
L
K
----------------------------------------------------------------------------------------------------------
46
PsiBlast_CBE
64.41
36%
-114
- C1 -
3MFU
1
CSKP_HUMAN
A:
[22-291]
------------------------------------------------------------------------------
F
E
D
V
Y
E
L
C
E
-
V
I
G
K
G
A
F
S
V
V
R
R
C
I
N
R
E
T
G
Q
Q
F
A
V
K
I
V
D
V
A
K
F
T
---
S
S
P
G
L
S
T
--
E
---
D
L
K
R
E
A
S
I
C
H
M
L
K
-
H
P
H
I
V
E
L
L
E
T
Y
S
S
D
G
M
L
Y
M
V
F
E
F
M
D
G
A
D
L
C
F
E
I
V
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R
A
D
A
G
F
V
Y
S
E
A
V
A
S
H
Y
M
R
Q
I
L
E
A
L
R
Y
C
H
D
N
N
I
I
H
R
D
V
K
P
E
N
V
L
-
L
A
S
K
E
N
S
A
P
V
K
L
G
D
F
--
G
V
A
I
Q
L
-
G
E
S
G
L
V
A
G
G
R
V
G
T
P
----
H
F
M
A
P
E
V
V
K
-
R
-----
E
P
Y
G
K
P
V
D
V
W
G
C
G
V
I
L
F
I
L
L
S
G
C
L
P
F
Y
G
----------------
T
K
E
R
L
F
E
G
I
I
K
G
K
Y
K
M
N
P
R
Q
W
S
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I
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E
S
A
K
D
L
V
R
R
M
L
M
L
D
P
A
E
R
I
T
V
Y
E
A
L
N
H
P
W
L
K
----------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
63.21
36%
-115
- C1 -
3I7C
1
?
A:
[24-291]
------------------------------------------------------------------------------
F
S
D
R
Y
K
G
Q
R
-
V
L
G
K
G
S
F
G
E
V
I
L
C
K
D
K
I
T
G
Q
E
C
A
V
K
V
I
S
--------
K
R
Q
V
K
Q
K
--
T
D
K
E
S
L
L
R
E
V
Q
L
L
K
Q
L
D
-
H
P
N
I
M
K
L
Y
E
F
F
E
D
K
G
Y
F
Y
L
V
G
E
V
Y
T
G
G
E
L
F
D
E
I
I
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R
K
R
----
F
S
E
V
D
A
A
R
I
I
R
Q
V
L
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G
I
T
Y
M
H
K
N
K
I
V
H
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E
N
L
L
-
L
E
S
K
S
K
D
A
N
I
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I
I
D
F
G
L
S
T
H
F
E
--------
A
S
K
K
M
K
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K
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G
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A
Y
Y
I
A
P
E
V
L
H
-
G
------
T
Y
D
E
K
C
D
V
W
S
T
G
V
I
L
Y
I
L
L
S
G
C
P
P
F
N
G
---------------
A
N
E
Y
D
I
L
K
K
V
E
K
G
K
Y
T
F
E
L
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Q
W
K
K
V
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E
S
A
K
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I
R
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M
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Y
V
P
S
M
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I
S
A
R
D
A
L
D
H
E
W
I
Q
T
Y
T
--
K
E
---------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
62.71
36%
-104
- C1 -
3MWU
1
?
A:
[14-314]
------------------------------------------------------------------------
L
Y
F
Q
G
T
F
A
E
R
Y
N
I
V
-
C
M
L
G
K
G
S
F
G
E
V
L
K
C
K
D
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I
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Q
Q
E
Y
A
V
K
V
I
N
--------
K
A
S
A
K
N
K
D
T
S
---
T
I
L
R
E
V
E
L
L
K
K
L
D
-
H
P
N
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M
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E
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Y
I
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E
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Y
T
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E
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F
D
E
I
I
K
R
K
R
----
F
S
E
H
D
A
A
R
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Q
V
F
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G
I
T
Y
M
H
K
H
N
I
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L
K
P
E
N
I
L
-
L
E
S
K
E
K
D
C
D
I
K
I
I
D
F
G
L
S
T
C
F
Q
Q
N
------------
D
R
I
G
T
A
Y
Y
I
A
P
E
V
L
R
-
G
------
T
Y
D
E
K
C
D
V
W
S
A
G
V
I
L
Y
I
L
L
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G
T
P
P
F
Y
G
K
N
E
Y
D
---------------
I
L
K
R
V
E
T
G
K
Y
A
F
D
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A
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A
T
Q
C
L
E
H
P
W
I
Q
K
Y
S
--
S
E
T
---
P
T
I
----
S
--
D
L
P
S
L
E
S
A
M
T
N
I
R
Q
F
Q
A
E
-----
K
K
L
A
Q
---------------------------------------------------------
6
PsiBlast_PDB
62.32
36%
-105
- C1 -
3NCG
1
?
A:
[14-314]
------------------------------------------------------------------------
L
Y
F
Q
G
T
F
A
E
R
Y
N
I
V
-
C
M
L
G
K
G
S
F
G
E
V
L
K
C
K
D
R
I
T
Q
Q
E
Y
A
V
K
V
I
N
--------
K
A
S
A
K
N
K
D
T
S
---
T
I
L
R
E
V
E
L
L
K
K
L
D
-
H
P
N
I
M
K
L
F
E
I
L
E
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S
F
Y
I
V
G
E
L
Y
T
G
G
E
L
F
D
E
I
I
K
R
K
R
----
F
S
E
H
D
A
A
R
I
I
K
Q
V
F
S
G
I
T
Y
M
H
K
H
N
I
V
H
R
D
L
K
P
E
N
I
L
-
L
E
S
K
E
K
D
C
D
I
K
I
I
D
F
G
L
S
T
C
F
Q
Q
N
--------
T
-----
I
G
T
A
Y
Y
I
A
P
E
V
L
R
-
G
------
T
Y
D
E
K
C
D
V
W
S
A
G
V
I
L
Y
I
L
L
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G
T
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P
F
Y
G
K
N
E
Y
D
---------------
I
L
K
R
V
E
T
G
K
Y
A
F
D
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A
K
D
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T
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C
L
E
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W
I
Q
K
Y
S
--
S
E
T
---
P
T
I
----
S
--
D
L
P
S
L
E
S
A
M
T
N
I
R
Q
F
Q
A
E
-----
K
K
L
A
Q
---------------------------------------------------------
4
PsiBlast_PDB
62.21
36%
-103
- C1 -
3IGO
8
?
A:
[17-314]
---------------------------------------------------------------------------
Q
G
T
F
A
E
R
Y
N
I
V
-
C
M
L
G
K
G
S
F
G
E
V
L
K
C
K
D
R
I
T
Q
Q
E
Y
A
V
K
V
I
N
--------
K
A
S
A
K
N
K
T-
S
---
T
I
L
R
E
V
E
L
L
K
K
L
D
-
H
P
N
I
M
K
L
F
E
I
L
E
D
S
S
S
F
Y
I
V
G
E
L
Y
T
G
G
E
L
F
D
E
I
I
K
R
K
R
----
F
S
E
H
D
A
A
R
I
I
K
Q
V
F
S
G
I
T
Y
M
H
K
H
N
I
V
H
R
D
L
K
P
E
N
I
L
-
L
E
S
K
E
K
D
C
D
I
K
I
I
D
F
G
L
S
T
C
F
Q
Q
N
--------
T
-------
T
A
Y
Y
I
A
P
E
V
L
R
-
G
------
T
Y
D
E
K
C
D
V
W
S
A
G
V
I
L
Y
I
L
L
S
G
T
P
P
F
Y
G
K
N
E
Y
D
---------------
I
L
K
R
V
E
T
G
K
Y
A
F
D
L
P
Q
W
R
T
I
S
D
D
A
K
D
L
I
R
K
M
L
T
F
H
P
S
L
R
I
T
A
T
Q
C
L
E
H
P
W
I
Q
K
Y
S
--
S
E
T
---
P
T
I
----
S
--
D
L
P
S
L
E
S
A
M
T
N
I
R
Q
F
Q
A
E
-----
K
K
L
A
Q
---------------------------------------------------------
16
PsiBlast_PDB
61.94
36%
-114
- C1 -
3T3U
5
?
A:
[24-291]
------------------------------------------------------------------------------
F
S
D
R
Y
K
G
Q
R
-
V
L
G
K
G
S
F
G
E
V
I
L
C
K
D
K
I
T
G
Q
E
C
A
V
K
V
I
S
--------
K
R
Q
V
K
Q
K
--
T
D
K
E
S
L
L
R
E
V
Q
L
L
K
Q
L
D
-
H
P
N
I
M
K
L
Y
E
F
F
E
D
K
G
Y
F
Y
L
V
G
E
V
Y
T
G
G
E
L
F
D
E
I
I
S
R
K
R
----
F
S
E
V
D
A
A
R
I
I
R
Q
V
L
S
G
I
T
Y
M
H
K
N
K
I
V
H
R
D
L
K
P
E
N
L
L
-
L
E
S
K
S
K
D
A
N
I
R
I
I
D
F
G
L
S
T
H
F
E
--------
A
S
K
K
M
K
D
K
I
G
T
A
Y
Y
I
A
P
E
V
L
H
-
G
------
T
Y
D
E
K
C
D
V
W
S
T
G
V
I
L
Y
I
L
L
S
G
C
P
P
F
N
G
---------------
A
N
E
Y
D
I
L
K
K
V
E
K
G
K
Y
T
F
E
L
P
Q
W
K
K
V
S
E
S
A
K
D
L
I
R
K
M
L
T
Y
V
P
S
M
R
I
S
A
R
D
A
L
D
H
E
W
I
Q
T
Y
T
--
K
E
---------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
61.57
36%
-112
- C1 -
3I7B
4
?
A:
[24-291]
------------------------------------------------------------------------------
F
S
D
R
Y
K
G
Q
R
-
V
L
G
K
G
S
F
G
E
V
I
L
C
K
D
K
I
T
G
Q
E
C
A
V
K
V
I
S
--------
K
R
Q
V
K
Q
K
--
T
D
K
E
S
L
L
R
E
V
Q
L
L
K
Q
L
D
-
H
P
N
I
M
K
L
Y
E
F
F
E
D
K
G
Y
F
Y
L
V
G
E
V
Y
T
G
G
E
L
F
D
E
I
I
S
R
K
R
----
F
S
E
V
D
A
A
R
I
I
R
Q
V
L
S
G
I
T
Y
M
H
K
N
K
I
V
H
R
D
L
K
P
E
N
L
L
-
L
E
S
K
S
K
D
A
N
I
R
I
I
D
F
G
L
S
T
H
F
E
--------
A
S
K
K
M
K
D
K
I
G
T
A
Y
Y
I
A
P
E
V
L
H
-
G
------
T
Y
D
E
K
C
D
V
W
S
T
G
V
I
L
Y
I
L
L
S
G
C
P
P
F
N
G
---------------
A
N
E
Y
D
I
L
K
K
V
E
K
G
K
Y
T
F
E
L
P
Q
W
K
K
V
S
E
S
A
K
D
L
I
R
K
M
L
T
Y
V
P
S
M
R
I
S
A
R
D
A
L
D
H
E
W
I
Q
T
Y
T
--
K
E
---------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
61.47
36%
-113
- C1 -
3N51
3
?
A:
[24-291]
------------------------------------------------------------------------------
F
S
D
R
Y
K
G
Q
R
-
V
L
G
K
G
S
F
G
E
V
I
L
C
K
D
K
I
T
G
Q
E
C
A
V
K
V
I
S
--------
K
R
Q
V
K
Q
K
--
T
D
K
E
S
L
L
R
E
V
Q
L
L
K
Q
L
D
-
H
P
N
I
M
K
L
Y
E
F
F
E
D
K
G
Y
F
Y
L
V
G
E
V
Y
T
G
G
E
L
F
D
E
I
I
S
R
K
R
----
F
S
E
V
D
A
A
R
I
I
R
Q
V
L
S
G
I
T
Y
M
H
K
N
K
I
V
H
R
D
L
K
P
E
N
L
L
-
L
E
S
K
S
K
D
A
N
I
R
I
I
D
F
G
L
S
T
H
F
E
--------
A
S
K
K
M
K
D
K
I
G
T
A
Y
Y
I
A
P
E
V
L
H
-
G
------
T
Y
D
E
K
C
D
V
W
S
T
G
V
I
L
Y
I
L
L
S
G
C
P
P
F
N
G
---------------
A
N
E
Y
D
I
L
K
K
V
E
K
G
K
Y
T
F
E
L
P
Q
W
K
K
V
S
E
S
A
K
D
L
I
R
K
M
L
T
Y
V
P
S
M
R
I
S
A
R
D
A
L
D
H
E
W
I
Q
T
Y
T
--
K
E
---------------------------------------------------------------------------------------------------
22
PsiBlast_CBE
61.40
36%
-115
- C1 -
3MA6
1
?
B:
[30-295]
------------------------------------------------------------------------------
F
S
D
R
Y
K
G
Q
R
-
V
L
G
K
G
S
F
G
E
V
I
L
C
K
D
K
I
T
G
Q
E
C
A
V
K
V
I
S
--------
K
R
Q
V
K
Q
---
T
DK
E
S
L
L
R
E
V
Q
L
L
K
Q
L
D
-
H
P
N
I
M
K
L
Y
E
F
F
E
D
K
G
Y
F
Y
L
V
G
E
V
Y
T
G
G
E
L
F
D
E
I
I
S
R
K
R
----
F
S
E
V
D
A
A
R
I
I
R
Q
V
L
S
G
I
T
Y
M
H
K
N
K
I
V
H
R
D
L
K
P
E
N
L
L
-
L
E
S
K
S
K
D
A
N
I
R
I
I
D
F
G
L
S
T
H
F
E
--------
A
S
K
K
M
K
D
K
I
G
T
A
Y
Y
I
A
P
E
V
L
H
-
G
------
T
Y
D
E
K
C
D
V
W
S
T
G
V
I
L
Y
I
L
L
S
G
C
P
P
F
N
G
---------------
A
N
E
Y
D
I
L
K
K
V
E
K
G
K
Y
T
F
E
L
P
Q
W
K
K
V
S
E
S
A
K
D
L
I
R
K
M
L
T
Y
V
P
S
M
R
I
S
A
R
D
A
L
D
H
E
W
I
Q
T
Y
T
-------------------------------------------------------------------------------------------------------
142
HHSearch
61.25
32%
-94
- C1 -
3Q5I
1
?
A:
[30-386]
--------------------------------------------------------------------------
K
E
G
K
I
G
E
S
Y
F
K
V
R
K
-
L
G
S
--
Y
G
E
V
L
L
C
K
E
K
N
G
H
S
E
K
A
I
K
V
I
K
--------
K
---
K
F
H
--
E
---
E
I
Y
N
E
I
S
L
L
K
S
L
-
D
H
P
N
I
I
K
L
F
D
V
F
E
D
K
K
Y
F
Y
L
V
T
E
F
Y
E
G
G
E
L
F
E
Q
I
I
N
R
H
K
----
F
D
E
C
D
A
A
N
I
M
K
Q
I
L
S
G
I
C
Y
L
H
K
H
N
I
V
H
R
D
I
K
P
E
N
I
L
-
L
E
N
K
N
S
L
L
N
I
K
I
V
D
F
G
L
S
S
F
F
S
K
D
Y
K
--------
L
R
D
R
L
G
T
A
Y
Y
I
A
P
E
V
L
K
-------
K
K
Y
N
E
K
C
D
V
W
S
C
G
V
I
M
Y
I
L
L
C
G
Y
P
P
F
G
G
Q
---------------
N
D
Q
D
I
I
K
K
V
E
K
G
K
Y
Y
F
D
F
N
D
W
K
N
I
S
D
E
A
K
E
L
I
K
L
M
L
T
Y
D
Y
N
K
R
C
T
A
E
E
A
L
N
S
R
W
I
K
K
Y
A
--
N
N
I
N
K
S
D
Q
K
T
L
C
G
A
L
S
N
M
-
R
K
F
E
G
S
Q
K
L
A
Q
A
A
I
L
F
I
G
S
K
--------
L
T
T
L
E
E
R
K
E
L
T
D
I
F
K
K
L
D
K
N
G
D
G
Q
L
D
-
K
K
E
L
I
E
G
Y
N
V
L
R
N
--------------
15
PsiBlast_PDB
61.20
36%
-111
- C1 -
3SXF
3
?
A:
[24-291]
------------------------------------------------------------------------------
F
S
D
R
Y
K
G
Q
R
-
V
L
G
K
G
S
F
G
E
V
I
L
C
K
D
K
I
T
G
Q
E
C
A
V
K
V
I
S
--------
K
R
Q
V
K
Q
K
--
T
D
K
E
S
L
L
R
E
V
Q
L
L
K
Q
L
D
-
H
P
N
I
M
K
L
Y
E
F
F
E
D
K
G
Y
F
Y
L
V
G
E
V
Y
T
G
G
E
L
F
D
E
I
I
S
R
K
R
----
F
S
E
V
D
A
A
R
I
I
R
Q
V
L
S
G
I
T
Y
M
H
K
N
K
I
V
H
R
D
L
K
P
E
N
L
L
-
L
E
S
K
S
K
D
A
N
I
R
I
I
D
F
G
L
S
T
H
F
E
--------
A
S
K
K
M
K
D
K
I
G
T
A
Y
Y
I
A
P
E
V
L
H
-
G
------
T
Y
D
E
K
C
D
V
W
S
T
G
V
I
L
Y
I
L
L
S
G
C
P
P
F
N
G
---------------
A
N
E
Y
D
I
L
K
K
V
E
K
G
K
Y
T
F
E
L
P
Q
W
K
K
V
S
E
S
A
K
D
L
I
R
K
M
L
T
Y
V
P
S
M
R
I
S
A
R
D
A
L
D
H
E
W
I
Q
T
Y
T
--
K
E
---------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
60.72
36%
-115
- C1 -
3MA6
1
?
A:
[30-296]
------------------------------------------------------------------------------
F
S
D
R
Y
K
G
Q
R
-
V
L
G
K
G
S
F
G
E
V
I
L
C
K
D
K
I
T
G
Q
E
C
A
V
K
V
I
S
--------
K
R
Q
V
K
Q
K
--
T
D
K
E
S
L
L
R
E
V
Q
L
L
K
Q
L
D
-
H
P
N
I
M
K
L
Y
E
F
F
E
D
K
G
Y
F
Y
L
V
G
E
V
Y
T
G
G
E
L
F
D
E
I
I
S
R
K
R
----
F
S
E
V
D
A
A
R
I
I
R
Q
V
L
S
G
I
T
Y
M
H
K
N
K
I
V
H
R
D
L
K
P
E
N
L
L
-
L
E
S
K
S
K
D
A
N
I
R
I
I
D
F
G
L
S
T
H
F
E
---------
S
K
K
M
K
D
K
I
G
T
A
Y
Y
I
A
P
E
V
L
H
-
G
------
T
Y
D
E
K
C
D
V
W
S
T
G
V
I
L
Y
I
L
L
S
G
C
P
P
F
N
G
---------------
A
N
E
Y
D
I
L
K
K
V
E
K
G
K
Y
T
F
E
L
P
Q
W
K
K
V
S
E
S
A
K
D
L
I
R
K
M
L
T
Y
V
P
S
M
R
I
S
A
R
D
A
L
D
H
E
W
I
Q
T
Y
T
--
K
----------------------------------------------------------------------------------------------------
42
PsiBlast_CBE
60.53
36%
-108
- C1 -
3BHH
1
KCC2B_HUMAN
A:
[4-264]
--------------------------------------------------------------------------------
D
E
Y
Q
L
Y
E
D
I
-
G
----
S
V
V
R
R
C
V
K
L
C
T
G
H
E
Y
A
A
K
I
I
N
--------
T
K
K
L
S
A
R
--
D
H
Q
-
K
L
E
R
E
A
R
I
C
-
R
L
L
K
H
S
N
I
V
R
L
H
D
S
I
S
E
E
G
F
H
Y
L
V
F
D
L
V
T
G
G
E
L
F
E
D
I
V
A
R
E
Y
----
Y
S
E
A
D
A
S
H
C
I
Q
Q
I
L
E
A
V
L
H
C
H
Q
M
G
V
V
H
R
D
L
K
P
E
N
L
L
-
L
A
S
K
C
K
G
A
A
V
K
L
A
D
F
--
G
L
A
I
E
V
Q
G
D
-----
Q
Q
A
W
F
G
F
A
G
T
P
G
Y
L
S
P
E
V
L
R
----
K
E
A
--
Y
G
K
P
V
D
I
W
A
C
G
V
I
L
Y
I
L
L
V
G
Y
P
P
F
---------
W
D
E
D
------
Q
H
K
L
Y
Q
Q
I
K
A
G
A
Y
D
F
P
S
P
E
W
D
T
V
T
P
E
A
K
N
L
I
N
Q
M
L
T
I
N
P
A
K
R
I
T
A
H
E
A
L
K
H
P
W
V
-----------------------------------------------------------------------------------------------------------
50
PsiBlast_CBE
59.69
34%
-104
- C1 -
2V7O
3
KCC2G_HUMAN
A:
[28-291]
-----------------------------------------------------------------------------
R
F
T
D
D
Y
Q
L
F
E
E
-
L
G
K
G
-
F
S
V
V
R
R
C
V
K
K
T
P
T
Q
E
Y
A
A
K
I
I
N
--------
T
K
K
L
S
A
R
--
D
H
Q
-
K
L
E
R
E
A
R
I
C
-
R
L
L
K
H
P
N
I
V
R
L
H
D
S
I
S
E
E
G
F
H
Y
L
V
F
D
L
V
T
G
G
E
L
F
E
D
I
V
A
R
E
Y
----
Y
S
E
A
D
A
S
H
C
I
H
Q
I
L
E
S
V
N
H
I
H
Q
H
D
I
V
H
R
D
L
K
P
E
N
L
L
-
L
A
S
K
C
K
G
A
A
V
K
L
A
D
F
--
G
L
A
I
E
V
Q
G
E
-----
Q
Q
A
W
F
G
F
A
G
T
P
G
Y
L
S
P
E
V
L
------
R
K
D
P
Y
G
K
P
V
D
I
W
A
C
G
V
I
L
Y
I
L
L
V
G
Y
P
P
F
---------
W
D
E
D
------
Q
H
K
L
Y
Q
Q
I
K
A
G
A
Y
D
F
P
S
P
E
W
D
T
V
T
P
E
A
K
N
L
I
N
Q
M
L
T
I
N
P
A
K
R
I
T
A
D
Q
A
L
K
H
P
W
V
-----------------------------------------------------------------------------------------------------------
41
PsiBlast_CBE
59.62
36%
-109
- C1 -
3BHH
1
KCC2B_HUMAN
B:
[4-264]
--------------------------------------------------------------------------------
D
E
Y
Q
L
Y
E
D
I
-
G
K
---
S
V
V
R
R
C
V
K
L
C
T
G
H
E
Y
A
A
K
I
I
N
--------
T
K
K
L
S
A
R
--
D
HQ-
K
L
E
R
E
A
R
I
C
-
R
L
L
K
H
S
N
I
V
R
L
H
D
S
I
S
E
E
G
F
H
Y
L
V
F
D
L
V
T
G
G
E
L
F
E
D
I
V
A
R
E
Y
----
Y
S
E
A
D
A
S
H
C
I
Q
Q
I
L
E
A
V
L
H
C
H
Q
M
G
V
V
H
R
D
L
K
P
E
N
L
L
-
L
A
S
K
C
K
G
A
A
V
K
L
A
D
F
--
G
L
A
I
E
V
Q
G
D
-----
Q
Q
A
W
F
G
F
A
G
T
P
G
Y
L
S
P
E
V
L
R
----
K
E
A
--
Y
G
K
P
V
D
I
W
A
C
G
V
I
L
Y
I
L
L
V
G
Y
P
P
F
---------
W
D
E
D
------
Q
H
K
L
Y
Q
Q
I
K
A
G
A
Y
D
F
P
S
P
E
W
D
T
V
T
P
E
A
K
N
L
I
N
Q
M
L
T
I
N
P
A
K
R
I
T
A
H
E
A
L
K
H
P
W
V
-----------------------------------------------------------------------------------------------------------
49
PsiBlast_CBE
59.22
34%
-110
- C1 -
3SOA
1
KCC2A_HUMAN
A:
[8-271]
-----------------------------------------------------------------------------
R
F
T
E
E
Y
Q
L
F
E
E
-
L
G
K
G
--
S
V
V
R
R
C
V
K
V
L
A
G
Q
E
Y
A
A
M
I
I
N
--------
T
K
K
L
S
A
R
--
D
H
Q
-
K
L
E
R
E
A
R
I
C
-
R
L
L
K
H
P
N
I
V
R
L
H
D
S
I
S
E
E
G
H
H
Y
L
I
F
D
L
V
T
G
G
E
L
F
E
D
I
V
A
R
E
Y
----
Y
S
E
A
D
A
S
H
C
I
Q
Q
I
L
E
A
V
L
H
C
H
Q
M
G
V
V
H
R
N
L
K
P
E
N
L
L
-
L
A
S
K
L
K
G
A
A
V
K
L
A
D
F
--
G
L
A
I
E
V
E
G
E
-----
Q
Q
A
W
F
G
F
A
G
T
P
G
Y
L
S
P
E
V
L
------
R
K
D
P
Y
G
K
P
V
D
L
W
A
C
G
V
I
L
Y
I
L
L
V
G
Y
P
P
F
---------
W
D
E
D
------
Q
H
R
L
Y
Q
Q
I
K
A
G
A
Y
D
F
P
S
P
E
W
D
T
V
T
P
E
A
K
D
L
I
N
K
M
L
T
I
N
P
S
K
R
I
T
A
A
E
A
L
K
H
P
W
I
-----------------------------------------------------------------------------------------------------------
36
PsiBlast_CBE
59.21
35%
-107
- C1 -
2WEL
7
KCC2D_HUMAN
A:
[4-264]
--------------------------------------------------------------------------------
D
E
Y
Q
L
F
E
E
-
L
G
K
G
A
F
S
V
V
R
R
C
M
K
I
P
T
G
Q
E
Y
A
A
K
I
I
N
--------
T
K
K
L
S
A
R
--
D
H
Q
-
K
L
E
R
E
A
R
I
C
-
R
L
L
K
H
P
N
I
V
R
L
H
D
S
I
S
E
E
G
F
H
Y
L
V
F
D
L
V
T
G
G
E
L
F
E
D
I
V
A
R
E
Y
----
Y
S
E
A
D
A
S
H
C
I
Q
Q
I
L
E
S
V
N
H
C
H
L
N
G
I
V
H
R
D
L
K
P
E
N
L
L
-
L
A
S
K
S
K
G
A
A
V
K
L
A
D
F
--
G
L
A
I
E
V
Q
G
D
-----
Q
Q
A
W
F
G
F
A
G
T
P
G
Y
L
S
P
E
V
L
------
R
K
D
P
Y
G
K
P
V
D
M
W
A
C
G
V
I
L
Y
I
L
L
V
G
Y
P
P
F
---------
W
D
E
D
------
Q
H
R
L
Y
Q
Q
I
K
A
G
A
Y
D
F
P
S
P
E
W
D
T
V
T
P
E
A
K
D
L
I
N
K
M
L
T
I
N
P
A
K
R
I
T
A
S
E
A
L
K
H
P
W
I
-----------------------------------------------------------------------------------------------------------
51
PsiBlast_CBE
59.18
34%
-112
- C1 -
2W4O
1
KCC4_HUMAN
A:
[45-313]
--------------------------------------------------------------------
G
S
N
R
D
A
L
S
D
F
F
E
-----
V
E
S
E
L
G
R
G
A
T
S
I
V
Y
R
C
K
Q
K
G
T
Q
K
P
Y
A
L
K
V
L
K
--------
K
-----------------
I
G
V
L
L
R
L
S
-
H
P
N
I
I
K
L
K
E
I
F
E
T
P
T
E
I
S
L
V
L
E
L
V
T
G
G
E
L
F
D
R
I
V
E
K
G
Y
----
Y
S
E
R
D
A
A
D
A
V
K
Q
I
L
E
A
V
A
Y
L
H
E
N
G
I
V
H
R
D
L
K
P
E
N
L
L
-
Y
A
T
P
A
P
D
A
P
L
K
I
A
D
F
------------------------
G
T
P
G
Y
C
A
P
E
I
L
R
-
G
C
A
-----
Y
G
P
E
V
D
M
W
S
V
G
I
I
T
Y
I
L
L
C
G
F
E
P
F
Y
D
--------
E
R
G
D
------
Q
F
M
F
R
R
I
L
N
C
E
Y
Y
F
I
S
P
W
W
D
E
V
S
L
N
A
K
D
L
V
R
K
L
I
V
L
D
P
K
K
R
L
T
T
F
Q
A
L
Q
H
P
W
V
T
G
K
A
-------------------------------------------------------------------------------------------------------
45
PsiBlast_CBE
58.85
34%
-108
- C1 -
2Y7J
1
PHKG2_HUMAN
A:
[99-364]
--------------------------------------------------------------------------------------
K
D
V
I
G
R
G
V
S
S
V
V
R
R
C
V
H
R
A
T
G
H
E
F
A
V
K
I
M
E
VTA
E
R
L
S
P
E
Q
L
E
E
V
R
--
E
---
A
T
R
R
E
T
H
I
L
R
Q
V
A
G
H
P
H
I
I
T
L
I
D
S
Y
E
S
S
S
F
M
F
L
V
F
D
L
M
R
K
G
E
L
F
D
Y
L
T
E
K
V
A
----
L
S
E
K
E
T
R
S
I
M
R
S
L
L
E
A
V
S
F
L
H
A
N
N
I
V
H
R
D
L
K
P
E
N
I
L
-
L
D
D
N
M
Q
---
I
R
L
S
D
F
G
F
S
--------
C
H
L
E
P
G
E
K
L
R
E
L
C
G
T
P
G
Y
L
A
P
E
I
L
K
C
S
M
D
E
T
H
P
G
Y
G
K
E
V
D
L
W
A
C
G
V
I
L
F
T
L
L
A
G
S
P
P
F
---------
W
H
R
R
------
Q
I
L
M
L
R
M
I
M
E
G
Q
Y
Q
F
S
S
P
E
W
D
D
R
S
S
T
V
K
D
L
I
S
R
L
L
Q
V
D
P
E
A
R
L
T
A
E
Q
A
L
Q
H
P
F
F
E
----------------------------------------------------------------------------------------------------------
44
PsiBlast_CBE
58.47
34%
-107
- C1 -
2Y7J
1
PHKG2_HUMAN
C:
[99-364]
--------------------------------------------------------------------------------------
K
D
V
I
G
R
G
V
S
S
V
V
R
R
C
V
H
R
A
T
G
H
E
F
A
V
K
I
M
E
VTAERLSP
E
Q
L
E
E
V
R
--
E
---
A
T
R
R
E
T
H
I
L
R
Q
V
A
G
H
P
H
I
I
T
L
I
D
S
Y
E
S
S
S
F
M
F
L
V
F
D
L
M
R
K
G
E
L
F
D
Y
L
T
E
K
V
A
----
L
S
E
K
E
T
R
S
I
M
R
S
L
L
E
A
V
S
F
L
H
A
N
N
I
V
H
R
D
L
K
P
E
N
I
L
-
L
D
D
N
M
Q
---
I
R
L
S
D
F
G
F
S
--------
C
H
L
E
P
G
E
K
L
R
E
L
C
G
T
P
G
Y
L
A
P
E
I
L
K
C
S
M
D
E
T
H
P
G
Y
G
K
E
V
D
L
W
A
C
G
V
I
L
F
T
L
L
A
G
S
P
P
F
---------
W
H
R
R
------
Q
I
L
M
L
R
M
I
M
E
G
Q
Y
Q
F
S
S
P
E
W
D
D
R
S
S
T
V
K
D
L
I
S
R
L
L
Q
V
D
P
E
A
R
L
T
A
E
Q
A
L
Q
H
P
F
F
E
----------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
58.38
37%
-99
- C1 -
2WEI
1
?
A:
[10-286]
--------------------------------------------------------------------
G
R
E
N
L
Y
F
Q
G
T
F
A
E
R
Y
N
I
V
-
C
M
L
G
K
G
S
F
G
E
V
L
K
C
K
D
R
I
T
Q
Q
E
Y
A
V
K
V
I
N
--------
K
A
S
A
K
N
K
D
T
S
---
T
I
L
R
E
V
E
L
L
K
K
L
D
-
H
P
N
I
M
K
L
F
E
I
L
E
D
S
S
S
F
Y
I
V
G
E
L
Y
T
G
G
E
L
F
D
E
I
I
K
R
K
R
----
F
S
E
H
D
A
A
R
I
I
K
Q
V
F
S
G
I
T
Y
M
H
K
H
N
I
V
H
R
D
L
K
P
E
N
I
L
-
L
E
S
K
E
K
D
C
D
I
K
I
I
D
F
G
L
S
T
C
F
Q
Q
N
--------
T
K
M
K
D
R
I
G
T
A
Y
Y
I
A
P
E
V
L
R
-
G
------
T
Y
D
E
K
C
D
V
W
S
A
G
V
I
L
Y
I
L
L
S
G
T
P
P
F
Y
G
K
N
E
Y
D
---------------
I
L
K
R
V
E
T
G
K
Y
A
F
D
L
P
Q
W
R
T
I
S
D
D
A
K
D
L
I
R
K
M
L
T
F
H
P
S
L
R
I
T
A
T
Q
C
L
E
H
P
W
I
Q
K
Y
S
--
S
E
---------------------------------------------------------------------------------------------------
39
PsiBlast_CBE
58.32
35%
-102
- C1 -
2VN9
1
KCC2D_HUMAN
B:
[4-264]
--------------------------------------------------------------------------------
D
E
Y
Q
L
F
E
E
-
L
G
K
G
A
F
S
V
V
R
R
C
M
K
I
P
T
G
Q
E
Y
A
A
K
I
I
N
--------
T
K
K
L
S
A
R
--
D
HQ-
K
L
E
R
E
A
R
I
C
-
R
L
L
K
H
P
N
I
V
R
L
H
D
S
I
S
E
E
G
F
H
Y
L
V
F
D
L
V
T
G
G
E
L
F
E
D
I
V
A
R
E
Y
----
Y
S
E
A
D
A
S
H
C
I
Q
Q
I
L
E
S
V
N
H
C
H
L
N
G
I
V
H
R
D
L
K
P
E
N
L
L
-
L
A
S
K
S
K
G
A
A
V
K
L
A
D
F
--
G
L
A
I
E
V
Q
G
D
-----
Q
Q
A
W
F
G
F
A
G
T
P
G
Y
L
S
P
E
V
L
------
R
K
D
P
Y
G
K
P
V
D
M
W
A
C
G
V
I
L
Y
I
L
L
V
G
Y
P
P
F
---------
W
D
E
D
------
Q
H
R
L
Y
Q
Q
I
K
A
G
A
Y
D
F
P
S
P
E
W
D
T
V
T
P
E
A
K
D
L
I
N
K
M
L
T
I
N
P
A
K
R
I
T
A
S
E
A
L
K
H
P
W
I
-----------------------------------------------------------------------------------------------------------
29
PsiBlast_CBE
58.31
34%
-106
- C1 -
3KN5
1
KS6A5_HUMAN
A:
[14-297]
------------------------------------------------------------------------------------
L
K
D
K
P
L
G
E
G
S
F
S
I
C
R
K
C
V
H
K
K
S
N
Q
A
F
A
V
K
I
I
S
--------
K
R
---
M
E
--
A
---
N
T
Q
K
E
I
T
A
L
K
L
C
E
G
H
P
N
I
V
K
L
H
E
V
F
H
D
Q
L
H
T
F
L
V
M
E
L
L
N
G
G
E
L
F
E
R
I
K
K
K
K
H
----
F
S
E
T
E
A
S
Y
I
M
R
K
L
V
S
A
V
S
H
M
H
D
V
G
V
V
H
R
D
L
K
P
E
N
L
L
-
F
T
D
----
L
E
I
K
I
I
D
F
G
F
A
R
-------
L
K
P
P
----------------------------
N
G
Y
D
E
S
C
D
L
W
S
L
G
V
I
L
Y
T
M
L
S
G
Q
V
P
F
Q
--------------
C
T
S
A
V
E
I
M
-
K
K
I
K
K
G
D
F
S
F
E
G
E
A
W
K
N
V
S
Q
E
A
K
D
L
I
Q
G
L
L
T
V
D
P
N
K
R
L
K
M
S
G
L
R
Y
N
E
W
L
Q
D
G
S
Q
L
S
S
N
P
-
L
M
T
P
----
D
--
I
L
-
G
S
S
G
A
A
----------------------------------------------------------------------------
40
PsiBlast_CBE
57.75
35%
-102
- C1 -
2VN9
2
KCC2D_HUMAN
A:
[4-264]
--------------------------------------------------------------------------------
D
E
Y
Q
L
F
E
E
-
L
G
K
G
A
F
S
V
V
R
R
C
M
K
I
P
T
G
Q
E
Y
A
A
K
I
I
N
--------
T
K
K
L
S
A
R
--
D
H
Q
-
K
L
E
R
E
A
R
I
C
-
R
L
L
K
H
P
N
I
V
R
L
H
D
S
I
S
E
E
G
F
H
Y
L
V
F
D
L
V
T
G
G
E
L
F
E
D
I
V
A
R
E
Y
----
Y
S
E
A
D
A
S
H
C
I
Q
Q
I
L
E
S
V
N
H
C
H
L
N
G
I
V
H
R
D
L
K
P
E
N
L
L
-
L
A
S
K
S
K
G
A
A
V
K
L
A
D
F
--
G
L
A
I
E
V
Q
G
D
-----
Q
Q
A
W
F
G
F
A
G
T
P
G
Y
L
S
P
E
V
L
------
R
K
D
P
Y
G
K
P
V
D
M
W
A
C
G
V
I
L
Y
I
L
L
V
G
Y
P
P
F
---------
W
D
E
D
------
Q
H
R
L
Y
Q
Q
I
K
A
G
A
Y
D
F
P
S
P
E
W
D
T
V
T
P
E
A
K
D
L
I
N
K
M
L
T
I
N
P
A
K
R
I
T
A
S
E
A
L
K
H
P
W
I
-----------------------------------------------------------------------------------------------------------
28
PsiBlast_CBE
55.72
34%
-97
- C1 -
3KN5
1
B:
[14-297]
------------------------------------------------------------------------------------
L
K
D
K
P
L
G
E
G
S
F
S
I
C
R
K
C
V
H
K
K
S
N
Q
A
F
A
V
K
I
I
S
--------
K
R
---
M
E
--
A
---
N
T
Q
K
E
I
T
A
L
K
L
C
E
G
H
P
N
I
V
K
L
H
E
V
F
H
D
Q
L
H
T
F
L
V
M
E
L
L
N
G
G
E
L
F
E
R
I
K
K
K
K
H
----
F
S
E
T
E
A
S
Y
I
M
R
K
L
V
S
A
V
S
H
M
H
D
V
G
V
V
H
R
D
L
K
P
E
N
L
L
-
F
T
D
----
L
E
I
K
I
I
D
F
G
F
A
R
-------
L
K
P
P
----------------------------
N
G
Y
D
E
S
C
D
L
W
S
L
G
V
I
L
Y
T
M
L
S
G
Q
V
P
F
Q
S
H
-------
D
R
S
L
T
C
T
S
A
V
E
I
M
-
K
K
I
K
K
G
D
F
S
F
E
G
E
A
W
K
N
V
S
Q
E
A
K
D
L
I
Q
G
L
L
T
V
D
P
N
K
R
L
K
M
S
G
L
R
Y
N
E
W
L
Q
D
G
S
Q
L
S
S
N
P
-
L
M
T
P
----
D
--
I
L
-
G
S
S
G
A
A
----------------------------------------------------------------------------
31
PsiBlast_CBE
55.52
38%
-107
- C1 -
2JAM
3
KCC1G_HUMAN
A:
[15-267]
---------------------------------------------------------------------------------------
E
V
L
G
S
G
A
F
S
E
V
F
L
V
K
Q
R
L
T
G
K
L
F
A
L
K
C
I
K
--------
K
S
-----------
S
L
E
N
E
I
A
V
L
K
K
I
K
-
H
E
N
I
V
T
L
E
D
I
Y
E
S
T
T
H
Y
Y
L
V
M
Q
L
V
S
G
G
E
L
F
D
R
I
L
E
R
G
V
----
Y
T
E
K
D
A
S
L
V
I
Q
Q
V
L
S
A
V
K
Y
L
H
E
N
G
I
V
H
R
D
L
K
P
E
N
L
L
-
Y
L
T
P
E
E
N
S
K
I
M
I
T
D
F
G
L
-
S
K
M
E
Q
N
G
I
M
S
--------
T
A
C
G
T
P
G
Y
V
A
P
E
V
L
------
A
Q
K
P
Y
S
K
A
V
D
C
W
S
I
G
V
I
T
Y
I
L
L
C
G
Y
P
P
F
Y
E
E
T
E
S
K
---------------
L
F
E
K
I
K
E
G
Y
Y
E
F
E
S
P
F
W
D
D
I
S
E
S
A
K
D
F
I
C
H
L
L
E
K
D
P
N
E
R
Y
T
C
E
K
A
L
S
H
P
W
I
D
G
---------------------------------------------------------------------------------------------------------
24
PsiBlast_CBE
55.00
35%
-100
- C1 -
2WNT
2
B:
[26-286]
-------------------------------------------------------------------------------
S
D
G
Y
V
V
K
E
T
I
-
G
V
G
S
Y
S
E
C
K
R
C
V
H
K
A
T
N
M
E
Y
A
V
K
V
I
D
--------
K
S
----
K
--
R
---
D
P
S
E
E
I
E
I
L
L
R
Y
G
Q
H
P
N
I
I
T
L
K
D
V
Y
D
D
G
K
H
V
Y
L
V
T
E
L
M
R
G
G
E
L
L
D
K
I
L
R
Q
K
F
----
F
S
E
R
E
A
S
F
V
L
H
T
I
G
K
T
V
E
Y
L
H
S
Q
G
V
V
H
R
D
L
K
P
S
N
I
L
Y
V
D
E
S
G
N
P
E
C
L
R
I
C
D
F
G
F
A
K
Q
L
R
A
E
N
G
L
-------
L
M
T
P
C
Y
----------
K
-
R
Q
G
-----
Y
D
E
G
C
D
I
W
S
L
G
I
L
L
Y
T
M
L
A
G
Y
T
P
F
-----
A
N
G
P
S
D
T
P
E
E
-------
I
L
T
R
I
G
S
G
K
F
T
L
S
G
G
N
W
N
T
V
S
E
T
A
K
D
L
V
S
K
M
L
H
V
D
P
H
Q
R
L
T
A
K
Q
V
L
Q
H
P
W
V
-----------------------------------------------------------------------------------------------------------
30
PsiBlast_CBE
53.97
38%
-104
- C1 -
2JAM
3
KCC1G_HUMAN
B:
[15-267]
---------------------------------------------------------------------------------------
E
V
L
G
S
G
A
F
S
E
V
F
L
V
K
Q
R
L
T
G
K
L
F
A
L
K
C
I
K
--------
K
S
-----------
S
L
E
N
E
I
A
V
L
K
K
I
K
-
H
E
N
I
V
T
L
E
D
I
Y
E
S
T
T
H
Y
Y
L
V
M
Q
L
V
S
G
G
E
L
F
D
R
I
L
E
R
G
V
----
Y
T
E
K
D
A
S
L
V
I
Q
Q
V
L
S
A
V
K
Y
L
H
E
N
G
I
V
H
R
D
L
K
P
E
N
L
L
-
Y
L
T
P
E
E
N
S
K
I
M
I
T
D
F
G
L
-
S
K
M
E
Q
N
G
I
M
S
--------
T
A
C
G
T
P
G
Y
V
A
P
E
V
L
------
A
Q
K
P
Y
S
K
A
V
D
C
W
S
I
G
V
I
T
Y
I
L
L
C
G
Y
P
P
F
Y
E
E
T
E
S
K
---------------
L
F
E
K
I
K
E
G
Y
Y
E
F
E
S
P
F
W
D
D
I
S
E
S
A
K
D
F
I
C
H
L
L
E
K
D
P
N
E
R
Y
T
C
E
K
A
L
S
H
P
W
I
D
G
---------------------------------------------------------------------------------------------------------