@TOME V2.3
(Nov 2016)

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Alignment:

3D Common Core:

Structural Clustering:

Modeller Result :

Complexes Modeling
Templates Information:
Sequence & Result Tab:

Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : NTRK1_HUMAN: (2013-07-23 )
MLRGGRRGQLGWHSWAAGPGSLLAWLILASAGAAPCPDACCPHGSSGLRCTRDGALDSLHHLPGAENLTELYIENQQHLQHLELRDLRGLGELRNLTIVKSGLRFVAPDAFHFTPRLSRLNLSFNALESLSWKTVQGLSLQELVLSGNPLHCSCALRWLQRWEEEGLGGVPEQKLQCHGQGPLAHMPNASCGVPTLKVQVPNASVDVGDDVLLRCQVEGRGLEQAGWILTELEQSATVMKSGGLPSLGLTLANVTSDLNRKNVTCWAENDVGRAEVSVQVNVSFPASVQLHTAVEMHHWCIPFSVDGQPAPSLRWLFNGSVLNETSFIFTEFLEPAANETVRHGCLRLNQPTHVNNGNYTLLAANPFGQASASIMAAFMDNPFEFNPEDPIPVSFSPVDTNSTSGDPVEKKDETPFGVSVAVGLAVFACLFLSTLLLVLNKCGRRNKFGINRPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQRHSIKDVHARLQALAQAPPVYLDVLG

Atome Classification :

(91 SA) .........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.....------..500.-----......510.-.-.....520.......530.-....--------------.----.540.....-.-.-550--........560.....-..570.......580.......590.......600.------......610.......620-.-........630.......640.......650......---.-----660.......670.---......-680.......690.......700.......710.......720...-....730........740---.....--....750.......760.......770.......780.......790....
(Atome) (Ident) (Tito) (Num) (Ligand) (Uniprot) MLRGGRRGQLGWHSWAAGPGSLLAWLILASAGAAPCPDACCPHGSSGLRCTRDGALDSLHHLPGAENLTELYIENQQHLQHLELRDLRGLGELRNLTIVKSGLRFVAPDAFHFTPRLSRLNLSFNALESLSWKTVQGLSLQELVLSGNPLHCSCALRWLQRWEEEGLGGVPEQKLQCHGQGPLAHMPNASCGVPTLKVQVPNASVDVGDDVLLRCQVEGRGLEQAGWILTELEQSATVMKSGGLPSLGLTLANVTSDLNRKNVTCWAENDVGRAEVSVQVNVSFPASVQLHTAVEMHHWCIPFSVDGQPAPSLRWLFNGSVLNETSFIFTEFLEPAANETVRHGCLRLNQPTHVNNGNYTLLAANPFGQASASIMAAFMDNPFEFNPEDPIPVSFSPVDTNSTSGDPVEKKDETPFGVSVAVGLAVFACLFLSTLLLVLNKCGRRNKFGINRPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYF------SDACVH-----HIKRRDIVLK-W-ELGEGAFGKVFLAECHNLL-PEQD--------------K----MLVAVKALK-E-A-S-E--SARQDFQREAELLTML-QHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRS------HGPDAKLLAGGEDVAPG---P-LGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLV---G-----QGLVVKIGDFGMSR---DIYSTD-YYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGK-QPWYQ-LSNTEAIDCI-----TQGRE--LERPRACPPEVYAIMRGCWQREPQQRHSIKDVHARLQALAQAPPVYLDVLG
22 PsiBlast_CBE 92.04100%-132 - C3 -4AOJ C:[33-322] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ACVH-----HIKRRDIVLK-W-ELGEGAFGKVFLAECHNLL-P-QD--------------K----MLVAVKALK-E-A-S-E--SARQDFQREAELLTML-QHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRS------HGPD------------G---P-LGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLV---G-----QGLVVKIGDFGM--------------------MLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGK-QPWYQ-LSNTEAIDCI-----TQGRE--LERPRACPPEVYAIMRGCWQREPQQRHSIKDVHARLQALAQAPP-------
23 PsiBlast_CBE 91.87100%-134 - C3 -4AOJ NTRK1_HUMAN B:[33-324] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ACVH-----HIKRRDIVLK-W-ELGEGAFGKVFLAECHNLL-P-----------------K----MLVAVKALK-E-A-S-E--SARQDFQREAELLTML-QHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRS------HGPD------------G---P-LGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLV---G-----QGLVVKIGDF-----------------------LPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGK-QPWYQ-LSNTEAIDCI-----TQGRE--LERPRACPPEVYAIMRGCWQREPQQRHSIKDVHARLQALAQAPPVY-----
122 HHSearch 91.72100%-135 - C3 -4AOJ NTRK1_HUMAN A:[33-322] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ACVH-----HIKRRDIVLK-W-ELGEGAFGKVFLAECHNLL-P-----------------K----MLVAVKALK-E-A-S-E--SARQDFQREAELLTML-QHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRS------HGPD-----------PG---P-LGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLV---G-----QGLVVKIGDFG--------------------TMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGK-QPWYQ-LSNTEAIDCI-----TQGRE--LERPRACPPEVYAIMRGCWQREPQQRHSIKDVHARLQALAQAPP-------
5 PsiBlast_PDB 86.0875%-123 - C3 -4AT3 A:[4-299] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DTFVQ-----HIKRHNIVLK-R-ELGEGAFGKVFLAECYNLC-------------------K----ILVAVKTL----A-S-D--NARKDFHREAELLTNL-QHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKFLRA------HGPDAVLMA--N--PPT---E-LTQSQMLHIAQQIAAGMVYLASQHFVHRDLATRNCLV---G-----ENLLVKIGDFGMSR-----YSTD-YYRVGGHTMLPIRWMPPESIMYRKFTTESDVWSLGVVLWEIFTYGK-QPWYQ-LSNNEVIECI-----TQGRV--LQRPRTCPQEVYELMLGCWQREPHMRKNIKGIHTLLQNLAKASPVYLDILG
6 PsiBlast_PDB 85.6375%-126 - C3 -4AT4 A:[4-299] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DTFVQ-----HIKRHNIVLK-R-ELGEGAFGKVFLAECYNLC-------------------K----ILVAVKTLK-D-A-S-D--NARKDFHREAELLTNL-QHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKFLRA------HGPDAVLMA-----PPT---E-LTQSQMLHIAQQIAAGMVYLASQHFVHRDLATRNCLV---G-----ENLLVKIGDFGMSR---DVYSTD-YYRVGGHTMLPIRWMPPESIMYRKFTTESDVWSLGVVLWEIFTYGK-QPWYQ-LSNNEVIECI-----TQGRV--LQRPRTCPQEVYELMLGCWQREPHMRKNIKGIHTLLQNLAKASPVYLDILG
7 PsiBlast_PDB 85.5375%-120 - C3 -4AT5 A:[4-299] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DTFVQ-----HIKRHNIVLK-R-ELGEGAFGKVFLAECYNL--------------------K----ILVAVKTLK-D-A-S-D--NARKDFHREAELLTNL-QHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKFLRA------HGPDAVLMAEGN--PPT---E-LTQSQMLHIAQQIAAGMVYLASQHFVHRDLATRNCLV---G-----ENLLVKIGDFGMSR---DVYSTD-YYRVGGHTMLPIRWMPPESIMYRKFTTESDVWSLGVVLWEIFTYGK-QPWYQ-LSNNEVIECI-----TQGRV--LQRPRTCPQEVYELMLGCWQREPHMRKNIKGIHTLLQNLAKASPVYLDILG
8 PsiBlast_PDB 84.5276%-129 - C3 -3V5Q NTRK3_HUMAN A:[9-297] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VQ-----HIKRRDIVLK-R-EL------KVFLAECYNLS-PTKD--------------K----MLVAVKAL----P-T-L--AARKDFQREAELLTNL-QHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKFLRA------HGP-----------------E-LGLSQMLHIASQIASGMVYLASQHFVHRDLATRNCLV---G-----ANLLVKIGDFGM-----DVYSTD-YYR----TMLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFTYGK-QPWFQ-LSNTEVIECI-----TQGRV--LERPRVCPKEVYDVMLGCWQREPQQRLNIKEIYKILHALGKATP-------
60 PsiBlast_CBE 75.9841%-120 - C3 -4FOB A:[51-335] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LK-----EVPRKNITLI-R-GLGHGAFGEVYEGQVS-------S--------------P----LQVAVKTLP-E-VCS-E--QDELDFLMEALIISKF-NHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRE------TRPR-----------PS---S-LAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCPG-----PGRVAKIGDFGMAR---DIYRA-------GCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGY-MPYPS-KSNQEVLEFV-----TSGGR--MDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIILERIEYCTQDPDV------
58 PsiBlast_CBE 75.7041%-124 - C3 -2XB7 A:[16-300] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LK-----EVPRKNITLI-R-GLGHGAFGEVYEGQVS----------------------P----LQVAVKTLP-E-VCS-E--QDELDFLMEALIISKF-NHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRE------TRPRPS--------QPS---S-LAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCPG-----PGRVAKIGDFGMA------------------AMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGY-MPYPS-KSNQEVLEFV-----TSGGR--MDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIILERIEYCTQDPDV------
59 PsiBlast_CBE 75.5041%-120 - C3 -4FOC A:[51-335] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LK-----EVPRKNITLI-R-GLGHGAFGEVYEGQVS-------S--------------P----LQVAVKTLP-E-VCS-E--QDELDFLMEALIISKF-NHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRE------TRPRPS--------QPS---S-LAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCPG-----PGRVAKIGDFGMAR---DIYR---------CAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGY-MPYPS-KSNQEVLEFV-----TSGGR--MDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIILERIEYCTQDPDV------
48 PsiBlast_CBE 75.3440%-112 - C3 -3LCS A:[30-326] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YCFAGKTSSISDLK-----EVPRKNITLI-R-GLGHGAFGEVYEGQVSGMP-NDPS--------------P----LQVAVKTLP-E-VCS-E--QDELDFLMEALIISKF-NHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRE------TRPRPS--------QPS---S-LAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCPG-----PGRVAKIGDFGMAR---DIYRAG-YYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGY-MPYPS-KSNQEVLEFV-----TSGGR--MDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIILERIEYCTQDPDV------
51 PsiBlast_CBE 75.2241%-124 - C3 -4DCE B:[31-315] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LK-----EVPRKNITLI-R-GLGH----EVYEGQVS-------S--------------P----LQVAVKTLP-E-VCS-E--QDELDFLMEALIISKF-NHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRE------TRPRPS--------QPS---S-LAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCPG-----PGRVAKIGDF-------------------GCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGY-MPYPS-KSNQEVLEFV-----TSGGR--MDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIILERIEYCTQDPDV------
50 PsiBlast_CBE 75.0941%-118 - C3 -4FOD A:[31-315] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LK-----EVPRKNITLI-R-GLGHGAFGEVYEGQVS-------S--------------P----LQVAVKTLP-E-VCS-E--QDELDFLMEALIISKF-NHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRE------TRPRPS--------QPS---S-LAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCPG-----PGRVAKIGDFGMAR---DIYRA--------CAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGY-MPYPS-KSNQEVLEFV-----TSGGR--MDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIILERIEYCTQDPDV------
49 PsiBlast_CBE 75.0541%-121 - C3 -4FNW A:[25-309] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LK-----EVPRKNITLI-R-GLG----GEVYEGQVS-------S--------------P----LQVAVKTLP-E-VCS-E--QDELDFLMEALIISKL-NHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRE------TRPRPS--------QPS---S-LAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCPG-----PGRVAKIGDFGMAR---DIYR---------CAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGY-MPYPS-KSNQEVLEFV-----TSGGR--MDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIILERIEYCTQDPDV------
57 PsiBlast_CBE 74.7641%-127 - C3 -2XBA A:[16-300] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LK-----EVPRKNITLI-R-GL-------VYEGQVS----------------------P----LQVAVKTLP-E-VCS-E--QDELDFLMEALIISKF-NHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRE------TRPRPS--------QPS---S-LAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCPG-----PGRVAKIGDFGMAR---DIY-----------AMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGY-MPYPS-KSNQEVLEFV-----TSGGR--MDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIILERIEYCTQDPDV------
130 HHSearch 74.6541%-119 - C3 -3CBL A:[110-375] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VLNHEDLVLG-E-QIGRGNFGEVFSGRLR------AD--------------N----TLVAVKSCR-E-TLP-P--DLKAKFLQEARILKQY-SHPNIVRLIGVCTQKQPIYIVMELVQGGDFLTFLRT------EGA-----------------R-LRVKTLLQMVGDAAAGMEYLESKCCIHRDLAARNCLV---T-----EKNVLKISDFGMSR---EEADGV-YAASGGLRQVPVKWTAPEALNYGRYSSESDVWSFGILLWETFSLGA-SPYPN-LSNQQTREFV-----EKGGR--LPCPELCPDAVFRLMEQCWAYEPGQRPSFSTIYQELQSIRKR---------
56 PsiBlast_CBE 74.6041%-121 - C3 -2YFX A:[24-308] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LK-----EVPRKNITLI-R-GLG--AFGEVYEGQV-----------------------P----LQVAVKTLP-E-VCS-E--QDELDFLMEALIISKF-NHQNIVRCIGVSLQSLPRFILMELMAGGDLKSFLRE------TRPRPS--------QPS---S-LAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCPG-----PGRVAKIGDFGMAR---DIYR-------GGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGY-MPYPS-KSNQEVLEFV-----TSGGR--MDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIILERIEYCTQDPDV------
54 PsiBlast_CBE 74.4941%-119 - C3 -4FNZ A:[25-309] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LK-----EVPRKNITLI-R-GLGH---GEVYEGQVSG------S--------------P----LQVAVKTLP-E-VCS-E--QDELDFLMEALIISKF-NHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRE------TRPRPS--------QPS---S-LAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCPG-----PGRVAKIGDF-------------------GCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGY-MPYPS-KSNQEVLEFV-----TSGGR--MDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIILERIEYCTQDPDV------
39 PsiBlast_CBE 74.4540%-111 - C3 -3L9P A:[50-349] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NPNYCFAGKTSSISDLK-----EVPRKNITLI-R-GLGHGAFGEVYEGQVSG------S--------------P----LQVAVKTLP-E-VCS-E--QDELDFLMEALIISKF-NHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRE------TRPRPS--------QPS---S-LAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCPG-----PGRVAKIGDFGMAR---DIYRAG-YYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGY-MPYPS-KSNQEVLEFV-----TSGGR--MDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIILERIEYCTQDPDV------
62 PsiBlast_CBE 74.4141%-124 - C3 -4FNY A:[25-309] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LK-----EVPRKNITLI-R-GLGH---GEVYEGQVSG---------------------P----LQVAVKTLP-E-VCS-E--QDELDFLMEALIISKF-NHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRE------TRPRPS----------------LAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCPG-----PGRVAKIGDF--------------------CAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGY-MPYPS-KSNQEVLEFV-----TSGGR--MDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIILERIEYCTQDPDV------
52 PsiBlast_CBE 74.2541%-120 - C3 -4DCE ALK_HUMAN A:[31-315] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LK-----EVPRKNITLI-R-GLGH---GEVYEGQVS------PS--------------P----LQVAVKTLP-E-VCS-E--QDELDFLMEALIISKF-NHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRE------TRPRPS--------QPS---S-LAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCPG-----PGRVAKIGDF------------------GGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGY-MPYPS-KSNQEVLEFV-----TSGGR--MDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIILERIEYCTQDPDV------
36 PsiBlast_CBE 74.2445%-116 - C3 -4BKJ ? A:[9-304] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RSRLRFK-E-KLGEGQFGEVHLCEVDS----PQDLVSLDFPLNVRKGHP----LLVAVKILRPD-A-T-K--NARNDFLKEVKIMSRL-KDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSA------HQLED---------------PTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLV---G-----ENFTIKIADFGMSR---NLYAGD-YY----RAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQ-LTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLH------------------
47 PsiBlast_CBE 74.2040%-107 - C3 -3LCT A:[27-326] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NPNYCFAGKTSSISDLK-----EVPRKNITLI-R-GLGHGAFGEVYEGQVSGMP-NDPS--------------P----LQVAVKTLP-E-VCS-E--QDELDFLMEALIISKF-NHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRE------TRPRPS--------QPS---S-LAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCPG-----PGRVAKIGDFGMAR---DIYRAG-YYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGY-MPYPS-KSNQEVLEFV-----TSGGR--MDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIILERIEYCTQDPDV------
61 PsiBlast_CBE 74.1841%-121 - C3 -4ANQ A:[39-323] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LK-----EVPRKNITLI-R-GLG--AFGEVYEGQV-----------------------P----LQVAVKTLP-E-VCS-E--QDELDFLMEALIISKF-NHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRE------TRPRPS--------QPS---S-LAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCPG-----PGRVAKIADFGMAR---DIYR-------GGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGY-MPYPS-KSNQEVLEFV-----TSGGR--MDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIILERIEYCTQDPDV------
64 PsiBlast_CBE 74.0741%-120 - C3 -4ANS A:[39-323] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LK-----EVPRKNITLI-R-GLG--AFGEVYEGQV-----------------------P----LQVAVKTLP-E-VCS-E--QDELDFLMEALIISKF-NHQNIVRCIGVSLQSLPRFILMELMAGGDLKSFLRE------TRPRPS--------QPS---S-LAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCPG-----PGRVAKIADFGMAR---DIYR-------GGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGY-MPYPS-KSNQEVLEFV-----TSGGR--MDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIILERIEYCTQDPDV------
28 PsiBlast_CBE 73.8342%-115 - C3 -3LW0 IGF1R_HUMAN B:[11-285] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EVAREKITMS-R-ELGQGSFGMVYEGVAKGVV-KDEP--------------E----TRVAIKTVN-E-AAS-M--RERIEFLNEASVMKEF-NCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRS------LRP-----------------P-PSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMV---A-----EDFTVKIGDFGMTR---DIYETD-YYRKG---LLPVRWMSPESLKDGVFTTYSDVWSFGVVLWEIATLAE-QPYQG-LSNEQVLRFV-----MEGGL--LDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISSIK--------------
35 PsiBlast_CBE 73.6445%-112 - C3 -4BKJ ? B:[9-304] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RSRLRFK-E-KLGEGQFGEVHLCEVDS----PQDLVSLDFPLNVRKGHP----LLVAVKILRPD-A-T-K--NARNDFLKEVKIMSRL-KDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSA------HQLEDK----------G---PTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLV---G-----ENFTIKIADFGMSR---NLYAGD-YY----RAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQ-LTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLH------------------
53 PsiBlast_CBE 73.5341%-119 - C3 -3AOX A:[41-325] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LK-----EVPRKNITLI-R-GLG----GEVYEGQVS----------------------P----LQVAVKTLP-E-VCS-E--QDELDFLMEALIISKF-NHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRE------TRPRPS--------QPS---S-LAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCPG-----PGRVAKIGDFGMAR---DIYRA--------CAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGY-MPYPS-KSNQEVLEFV-----TSGGR--MDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIILERIEYCTQDPDV------
16 PsiBlast_PDB 73.2742%-117 - C3 -3LW0 IGF1R_HUMAN A:[11-285] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EVAREKITMS-R-ELGQGSFGMVYEGVAKGVV-KDEP--------------E----TRVAIKTVN-E-AAS-M--RERIEFLNEASVMKEF-NCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRS------LRP-----------------P-PSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMV---A-----EDFTVKIGDFGMTR---DIYETD-YYRKG---LLPVRWMSPESLKDGVFTTYSDVWSFGVVLWEIATLAE-QPYQG-LSNEQVLRFV-----MEGGL--LDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISSIK--------------
27 PsiBlast_CBE 73.2342%-116 - C3 -3LW0 IGF1R_HUMAN C:[11-285] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EVAREKITMS-R-ELGQGSFGMVYEGVAKGVV-KDEP--------------E----TRVAIKTVN-E-AAS-M--RERIEFLNEASVMKEF-NCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRS------LRP-----------------P-PSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMV---A-----EDFTVKIGDFGMTR---DIYETD-YYRKG---LLPVRWMSPESLKDGVFTTYSDVWSFGVVLWEIATLAE-QPYQG-LSNEQVLRFV-----MEGGL--LDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISSIK--------------
26 PsiBlast_CBE 73.0242%-114 - C3 -3LW0 D:[11-285] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EVAREKITMS-R-ELGQGSFGMVYEGVAKGVV-KDEP--------------E----TRVAIKTVN-E-AAS-M--RERIEFLNEASVMKEF-NCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRS------LRP-----------------P-PSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMV---A-----EDFTVKIGDFGMTR---DIYETD-YYRKG---LLPVRWMSPESLKDGVFTTYSDVWSFGVVLWEIATLAE-QPYQG-LSNEQVLRFV-----MEGGL--LDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISSIK--------------
37 PsiBlast_CBE 72.8745%-106 - C3 -3ZOS B:[9-304] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RSRLRFK-E-KLGEGQFGEVHLCEVDS----PQDLVSLDFPLNVRKGHP----LLVAVKILRPD-A-T-K--NARNDFLKEVKIMSRL-KDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSA------HQLEDK---------QG---PTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLV---G-----ENFTIKIADFGMSR---NLYAGD-YYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQ-LTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLH------------------
24 PsiBlast_CBE 72.5441%-114 - C3 -1JQH IGF1R_HUMAN B:[6-289] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ADVYVPDEWEVAREKITMS-R-ELGQGSFGMVYEGVAKGVV-KDEP--------------E----TRVAIKTVN-E-AAS-M--RERIEFLNEASVMKEF-NCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRS------LRP-----------------P-PSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMV---A-----EDFTVKIGDFGMT-----------YYRKGGKGLLPVRWMSPESLKDGVFTTYSDVWSFGVVLWEIATLAE-QPYQG-LSNEQVLRFV-----MEGGL--LDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISSIK--------------
81 PsiBlast_CBE 72.5339%-118 - C3 -3ZBF ? A:[32-306] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------REKLTLR-L-LLGS---GEVYEGTAVDILGVGSG--------------E----IKVAVKTLK-K-G-STD--QEKIEFLKEAHLMSKF-NHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATFYGPLLTLVD------------------LVDLCVDISKGCVYLERMHFIHRDLAARNCLV---SVKDYTSPRIVKIGDFGLAR---DIY-------------LPVRWMAPESLMDGIFTTQSDVWSFGILIWEILTLGH-QPYPA-HSNLDVLNYV-----QTGGR--LEPPRNCPDDLWNLMTQCWAQEPDQRPTFHRIQDQLQ--------------
38 PsiBlast_CBE 72.4645%-109 - C3 -3ZOS DDR1_HUMAN A:[9-304] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RSRLRFK-E-KLGEGQFGEVHLCEVDS----PQDLVSLDFPLNVRKGHP----LLVAVKILRPD-A-T-K--NARNDFLKEVKIMSRL-KDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSA------HQLED--------AAQG---PTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLV---G-----ENFTIKIADFGMSR---NLYAGD-YYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQ-LTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLH------------------
19 PsiBlast_PDB 72.4341%-115 - C3 -2OJ9 A:[14-288] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EVAREKITMS-R-ELGQGSFGMVYEGVAKGVV-KDEP--------------E----TRVAIKTVN-E-AAS-M--RERIEFLNEASVMKEF-NCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRS------LRPE----------------P-PSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMV---A-----EDFTVKIGDFGMTR---DIYETD-YYRKGGKGLLPVRWMSPESLKDGVFTTYSDVWSFGVVLWEIATLAE-QPYQG-LSNEQVLRFV-----MEGGL--LDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISSIK--------------