@TOME V2.3
(Nov 2016)

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Alignment:

3D Common Core:

Structural Clustering:

Modeller Result :

Complexes Modeling
Templates Information:
Sequence & Result Tab:

Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : NTRK3_HUMAN: (2013-07-24 )
MDVSLCPAKCSFWRIFLLGSVWLDYVGSVLACPANCVCSKTEINCRRPDDGNLFPLLEGQDSGNSNGNASINITDISRNITSIHIENWRSLHTLNAVDMELYTGLQKLTIKNSGLRSIQPRAFAKNPHLRYINLSSNRLTTLSWQLFQTLSLRELQLEQNFFNCSCDIRWMQLWQEQGEAKLNSQNLYCINADGSQLPLFRMNISQCDLPEISVSHVNLTVREGDNAVITCNGSGSPLPDVDWIVTGLQSINTHQTNLNWTNVHAINLTLVNVTSEDNGFTLTCIAENVVGMSNASVALTVYYPPRVVSLEEPELRLEHCIEFVVRGNPPPTLHWLHNGQPLRESKIIHVEYYQEGEISEGCLLFNKPTHYNNGNYTLIAKNPLGTANQTINGHFLKEPFPESTDNFILFDEVSPTPPITVTHKPEEDTFGVSIAVGLAAFACVLLVVLFVMINKYGRRSKFGMKGPVAVISGEEDSASPLHHINHGITTPSSLDAGPDTVVIGMTRIPVIENPQYFRQGHNCHKPDTYVQHIKRRDIVLKRELGEGAFGKVFLAECYNLSPTKDKMLVAVKALKDPTLAARKDFQREAELLTNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGELGLSQMLHIASQIASGMVYLASQHFVHRDLATRNCLVGANLLVKIGDFGMSRDVYSTDYYRLFNPSGNDFCIWCEVGGHTMLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFTYGKQPWFQLSNTEVIECITQGRVLERPRVCPKEVYDVMLGCWQREPQQRLNIKEIYKILHALGKATPIYLDILG

Atome Classification :

(85 SA) .........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.....-..530.......540.-.......550.....----------..560....-...570...-.-.-.-.--580..---.....590.......600.......610.......620.......630.......640.......650..----.....660.......670.......680.....---.---.690.......700......-.710.......720.......730.......740.......750.......760......-.770.......780.-----....--..790.......800.......810.......820.......830.......
(Atome) (Ident) (Tito) (Num) (Ligand) (Uniprot) MDVSLCPAKCSFWRIFLLGSVWLDYVGSVLACPANCVCSKTEINCRRPDDGNLFPLLEGQDSGNSNGNASINITDISRNITSIHIENWRSLHTLNAVDMELYTGLQKLTIKNSGLRSIQPRAFAKNPHLRYINLSSNRLTTLSWQLFQTLSLRELQLEQNFFNCSCDIRWMQLWQEQGEAKLNSQNLYCINADGSQLPLFRMNISQCDLPEISVSHVNLTVREGDNAVITCNGSGSPLPDVDWIVTGLQSINTHQTNLNWTNVHAINLTLVNVTSEDNGFTLTCIAENVVGMSNASVALTVYYPPRVVSLEEPELRLEHCIEFVVRGNPPPTLHWLHNGQPLRESKIIHVEYYQEGEISEGCLLFNKPTHYNNGNYTLIAKNPLGTANQTINGHFLKEPFPESTDNFILFDEVSPTPPITVTHKPEEDTFGVSIAVGLAAFACVLLVVLFVMINKYGRRSKFGMKGPVAVISGEEDSASPLHHINHGITTPSSLDAGPDTVVIGMTRIPVIENPQYFRQGHNCHKPD-TYVQHIKRRDIVLK-R-ELGEGAFGKVFLAEC----------YNLSPTKDK-MLVAVKALK-D-P-T-L--AARKD---FQREAELLTNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGELGLS----QMLHIASQIASGMVYLASQHFVHRDLATRNCLV---G---ANLLVKIGDFGMSRDVYSTD-YYRLFNPSGNDFCIWCEVGGHTMLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFTYGK-QPWFQLSNTEVIECI-----TQGR--VLERPRVCPKEVYDVMLGCWQREPQQRLNIKEIYKILHALGKATPIYLDILG
1 PsiBlast_PDB 96.5095%-134 - C5 -3V5Q NTRK3_HUMAN A:[8-297] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HVQHIKRRDIVLK-R-EL------KVFLAEC----------YNLSPTKDK-MLVAVKAL----P-T-L--AARKD---FQREAELLTNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHGP---------------ELGLS----QMLHIASQIASGMVYLASQHFVHRDLATRNCLV---G---ANLLVKIGDFGM--DVYSTD-YYR------------------TMLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFTYGK-QPWFQLSNTEVIECI-----TQGR--VLERPRVCPKEVYDVMLGCWQREPQQRLNIKEIYKILHALGKATP-------
4 PsiBlast_PDB 93.2478%-120 - C5 -4AT5 A:[4-299] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D-TFVQHIKRHNIVLK-R-ELGEGAFGKVFLAEC----------YNL-----K-ILVAVKTLK-D-A-S-D--NARKD---FHREAELLTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKFLRAHGPDAVLMAEGNP---PTELTQS----QMLHIAQQIAAGMVYLASQHFVHRDLATRNCLV---G---ENLLVKIGDFGMSRDVYSTD-YYR--------------VGGHTMLPIRWMPPESIMYRKFTTESDVWSLGVVLWEIFTYGK-QPWYQLSNNEVIECI-----TQGR--VLQRPRTCPQEVYELMLGCWQREPHMRKNIKGIHTLLQNLAKASPVYLDILG
2 PsiBlast_PDB 93.1378%-125 - C5 -4AT3 A:[4-299] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D-TFVQHIKRHNIVLK-R-ELGEGAFGKVFLAEC----------YNLC----K-ILVAVKTL----A-S-D--NARKD---FHREAELLTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKFLRAHGPDAVLMA--NP---PTELTQS----QMLHIAQQIAAGMVYLASQHFVHRDLATRNCLV---G---ENLLVKIGDFGMSR--YSTD-YYR--------------VGGHTMLPIRWMPPESIMYRKFTTESDVWSLGVVLWEIFTYGK-QPWYQLSNNEVIECI-----TQGR--VLQRPRTCPQEVYELMLGCWQREPHMRKNIKGIHTLLQNLAKASPVYLDILG
3 PsiBlast_PDB 92.2878%-125 - C5 -4AT4 A:[4-299] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D-TFVQHIKRHNIVLK-R-ELGEGAFGKVFLAEC----------YNLC----K-ILVAVKTLK-D-A-S-D--NARKD---FHREAELLTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKFLRAHGPDAVLMA---P---PTELTQS----QMLHIAQQIAAGMVYLASQHFVHRDLATRNCLV---G---ENLLVKIGDFGMSRDVYSTD-YYR--------------VGGHTMLPIRWMPPESIMYRKFTTESDVWSLGVVLWEIFTYGK-QPWYQLSNNEVIECI-----TQGR--VLQRPRTCPQEVYELMLGCWQREPHMRKNIKGIHTLLQNLAKASPVYLDILG
120 HHSearch 91.1273%-129 - C5 -4AOJ NTRK1_HUMAN A:[33-322] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ACVHHIKRRDIVLK-W-ELGEGAFGKVFLAEC----------HNLLP---K-MLVAVKALK-E-A-S-E--SARQD---FQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPD------------PGPLGLG----QLLAVASQVAAGMVYLAGLHFVHRDLATRNCLV---G---QGLVVKIGDFG-------------------------------TMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGK-QPWYQLSNTEAIDCI-----TQGR--ELERPRACPPEVYAIMRGCWQREPQQRHSIKDVHARLQALAQAPP-------
21 PsiBlast_CBE 90.3070%-126 - C5 -4AOJ C:[33-322] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ACVHHIKRRDIVLK-W-ELGEGAFGKVFLAEC----------HNLLP-QDK-MLVAVKALK-E-A-S-E--SARQD---FQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPD-------------GPLGLG----QLLAVASQVAAGMVYLAGLHFVHRDLATRNCLV---G---QGLVVKIGDFGM-------------------------------MLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGK-QPWYQLSNTEAIDCI-----TQGR--ELERPRACPPEVYAIMRGCWQREPQQRHSIKDVHARLQALAQAPP-------
22 PsiBlast_CBE 90.0370%-129 - C5 -4AOJ NTRK1_HUMAN B:[33-324] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ACVHHIKRRDIVLK-W-ELGEGAFGKVFLAEC----------HNLLP---K-MLVAVKALK-E-A-S-E--SARQD---FQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPD-------------GPLGLG----QLLAVASQVAAGMVYLAGLHFVHRDLATRNCLV---G---QGLVVKIGDF----------------------------------LPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGK-QPWYQLSNTEAIDCI-----TQGR--ELERPRACPPEVYAIMRGCWQREPQQRHSIKDVHARLQALAQAPPVY-----
13 PsiBlast_PDB 77.8543%-119 - C5 -4BKJ ? A:[9-307] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RSRLRFK-E-KLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPD-A-T-K--NARND---FLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLED----------------PTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLV---G---ENFTIKIADFGMSRNLYAGD-YY------------------RAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFL---------------
28 PsiBlast_CBE 77.7739%-110 - C5 -3EKN A:[8-287] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YVPD-EW--EVSREKITLL-R-ELGQGSFGMVYEGNA----------RDIIKGEAE-TRVAVKTVN-ESA-S-L--RERIE---FLNEASVMKGFTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRSLRPEA------ENNPGRPPPTLQ----EMIQMAAEIADGMAYLNAKKFVHRNLAARNCMV---A---HDFTVKIGDFGMTRDIYETD-YYR--------------KG---LLPVRWMAPESLKDGVFTTSSDMWSFGVVLWEITSLAE-QPYQGLSNEQVLKFV-----MDGG--YLDQPDNCPERVTDLMRMCWQFNPNMRPTFLEIVNLL---------------
12 PsiBlast_PDB 77.5343%-114 - C5 -3ZOS DDR1_HUMAN A:[9-307] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RSRLRFK-E-KLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPD-A-T-K--NARND---FLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLED------------AAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLV---G---ENFTIKIADFGMSRNLYAGD-YYR--------------VQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFL---------------
128 HHSearch 77.5240%-119 - C5 -3CBL A:[110-375] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VLNHEDLVLG-E-QIGRGNFGEVFSGRL----------R-----ADN-TLVAVKSCR-E-TLP-P--DLKAK---FLQEARILKQYSHPNIVRLIGVCTQKQPIYIVMELVQGGDFLTFLRTEGA---------------RLRVK----TLLQMVGDAAAGMEYLESKCCIHRDLAARNCLV---T---EKNVLKISDFGMSREEADGV-YAA--------------SGGLRQVPVKWTAPEALNYGRYSSESDVWSFGILLWETFSLGA-SPYPNLSNQQTREFV-----EKGG--RLPCPELCPDAVFRLMEQCWAYEPGQRPSFSTIYQELQSIRKR---------
25 PsiBlast_CBE 77.3743%-117 - C5 -4BKJ ? B:[9-307] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RSRLRFK-E-KLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPD-A-T-K--NARND---FLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDK--------------GPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLV---G---ENFTIKIADFGMSRNLYAGD-YY------------------RAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFL---------------
26 PsiBlast_CBE 77.2443%-110 - C5 -3ZOS B:[9-307] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RSRLRFK-E-KLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPD-A-T-K--NARND---FLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDK-------------QGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLV---G---ENFTIKIADFGMSRNLYAGD-YYR--------------VQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHRFL---------------
66 PsiBlast_CBE 77.0837%-120 - C5 -1MQB EPHA2_HUMAN A:[38-310] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TTEIHPSCVTRQ-K-VIGAGEFGEVYKG-M----------LKT---KKE-VPVAIKTLK-A-GYT-E--KQRVD---FLGEAGIMGQFSHHNIIRLEGVISKYKPMMIITEYMENGALDKFLR---------------EKDGEFSVL----QLVGMLRGIAAGMKYLANMNYVHRDLAARNILV---N---SNLVCKVSDFGL-------------------K------------IPIRWTAPEAISYRKFTSASDVWSFGIVMWEVMTYGE-RPYWELSNHEVMKAI-----NDGF--RLPTPMDCPSAIYQLMMQCWQQERARRPKFADIVSILDKLIRA---------
27 PsiBlast_CBE 76.8640%-109 - C5 -3ETA B:[12-285] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EVSREKITLL-R-ELGQGSFGMVYEGNA----------RDIIKGEAE-TRVAVKTVN-ESA-S-L--RERIE---FLNEASVMKGFTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRSLRPEA----ENNP--GRPPPTLQ----EMIQMAAEIADGMAYLNAKKFVHRDLAARNCMV---A---HDFTVKIGDFGMTRDIYETD-YYR--------------K--KGLLPVRWMAPESLKDGVFTTSSDMWSFGVVLWEITSLAE-QPYQGLSNEQVLKFV-----MDGG--YLDQPDNCPERVTDLMRMCWQFNPKMRPTFLEIVNLL---------------
65 PsiBlast_CBE 76.5737%-120 - C5 -1MQB B:[35-310] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LKFTTEIHPSCVTRQ-K-VIGAGEFGEVYKG-M----------LKT----KE-VPVAIKTLK-A-GYT-E--KQRVD---FLGEAGIMGQFSHHNIIRLEGVISKYKPMMIITEYMENGALDKFLR---------------EKDGEFSVL----QLVGMLRGIAAGMKYLANMNYVHRDLAARNILV---N---SNLVCKVSDFGLSR-VL--------------K------------IPIRWTAPEAISYRKFTSASDVWSFGIVMWEVMTYGE-RPYWELSNHEVMKAI-----NDGF--RLPTPMDCPSAIYQLMMQCWQQERARRPKFADIVSILDKLIRA---------
139 HHSearch 76.5035%-114 - C5 -4FL3 KSYK_HUMAN A:[365-630] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LDRKLLTLEDK-ELGSGNFGTVKKGYY----------QM---KKVV-KTVAVKILK-N-E-A-NDPALKDE---LLAEANVMQQLDNPYIVRMIGICE-AESWMLVMEMAELGPLNKYLQQNR----------------HVKDK----NIIELVHQVSMGMKYLEESNFVHRDLAARNVLL---V---TQHYAKISDFGLSKALRA---------------------------PVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQ-KPYRGMKGSEVTAML-----EKGE--RMGCPAGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNYY-----------
29 PsiBlast_CBE 76.3340%-109 - C5 -1I44 A:[9-286] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PD-EW--EVSREKITLL-R-ELGQGSFGMVYEGNA----------RDIIKGEAE-TRVAVKTVN-ESA-S-L--RERIE---FLNEASVMKGFTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRSLRPEA----ENNP--GRPPPTLQ----EMIQMAAEIADGMAYLNAKKFVHRDLAARNCMV---A---HDFTVKIGDFGMT-------------------------------LPVRWMAPESLKDGVFTTSSDMWSFGVVLWEITSLAE-QPYQGLSNEQVLKFV-----MDGG--YLDQPDNCPERVTDLMRMCWQFNPKMRPTFLEIVNLL---------------
132 HHSearch 76.0136%-113 - C5 -2OZO ZAP70_HUMAN A:[331-598] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FLKRDNLLIA-DIELGCGNFGSVRQGVY----------RM---RKKQ-IDVAIKVLK-Q-G-TEK--ADTEE---MMREAQIMHQLDNPYIVRLIGVCQA-EALMLVMEMAGGGPLHKFLVGK---------------REEIPVS----NVAELLHQVSMGMKYLEEKNFVHRNLAARNVLL---V---NRHYAKISDFGLSKALG----------------------------PLKWYAPECINFRKFSSRSDVWSYGVTMWEALSYGQ-KPYKKMKGPEVMAFI-----EQGK--RMECPPECPPELYALMSDCWIYKWEDRPDFLTVEQRMRACYY----------
18 PsiBlast_PDB 75.6940%-109 - C5 -3ETA INSR_HUMAN A:[12-285] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EVSREKITLL-R-ELGQGSFGMVYEGNA----------RDIIKGEAE-TRVAVKTVN-ESA-S-L--RERIE---FLNEASVMKGFTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRSLRPEA----ENNP--GRPPPTLQ----EMIQMAAEIADGMAYLNAKKFVHRDLAARNCMV---A---HDFTVKIGDFGMTRDIYETD-YYR--------------KG-KGLLPVRWMAPESLKDGVFTTSSDMWSFGVVLWEITSLAE-QPYQGLSNEQVLKFV-----MDGG--YLDQPDNCPERVTDLMRMCWQFNPKMRPTFLEIVNLL---------------
140 HHSearch 75.6541%-110 - C5 -3L9P A:[66-347] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KEVPRKNITLI-R-GLGHGAFGEVYEGQV----------SG-----SP-LQVAVKTLP-E-VCS-E--QDELD---FLMEALIISKFNHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRETRPRP---------SQPSSLAML----DLLHVARDIACGCQYLEENHFIHRDIAARNCLL---TCPGPGRVAKIGDFGMARDIYRAG-YYR--------------KGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGY-MPYPSKSNQEVLEFV-----TSGG--RMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIILERIEYCTQDP--------
124 HHSearch 75.6340%-123 * C5 *4I4E A:[11-276] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EIQRERIELG-R-CIGEGQFGDVHQGIY------------MSP-NPA-LAVAIKTCK-NCT-S-D--SVREK---FLQEALTMRQFDHPHIVKLIGVITEN-PVWIIMELCTLGELRSFLQVRK---------------YSLDLA----SLILYAYQLSTALAYLESKRFVHRDIAARNVLV---S---SNDCVKLGDF----------------------------------LPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGV-KPFQGVKNNDVIGRI-----ENGE--RLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILE----------
20 PsiBlast_PDB 75.6339%-115 - C5 -3EKK A:[6-287] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SVYVPD-EW--EVSREKITLL-R-ELGQGSFGMVYEGNA----------RDIIKGEAE-TRVAVKTVN-ESA-S-L--RERIE---FLNEASVMKGFTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRSLRPEA------ENNPGRPPPTLQ----EMIQMAAEIADGMAYLNAKKFVHRNLAARNCMV---A---HDFTVKIGDF---------------------------------LLPVRWMAPESLKDGVFTTSSDMWSFGVVLWEITSLAE-QPYQGLSNEQVLKFV-----MDGG--YLDQPDNCPERVTDLMRMCWQFNPNMRPTFLEIVNLL---------------
89 PsiBlast_CBE 75.1836%-118 - C5 -3IK3 ABL1_MOUSE A:[9-275] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EMERTDITMK-H-KLGGGQYGEVYEGVW----------KKYSLT------VAVKTLK-E-D-T-M--EV-EE---FLKEAAVMKEIKHPNLVQLLGVCTREPPFYIIIEFMTYGNLLDYLRECN--------------RQEVSAV----VLLYMATQISSAMEYLEKKNFIHRDLAARNCLV---G---ENHLVKVADFGLS--------TYTAH--AGAKF------------PIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGM-SPYPGIDLSQVYELL-----EKDY--RMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSI------
47 PsiBlast_CBE 75.1338%-117 - C5 -4DCE B:[17-302] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PNYSFAGKTSSISD---LKEVPRKNITLI-R-GLGH----EVYEGQV----------S------SP-LQVAVKTL----P-E-V--CSEQDELDFLMEALIISKFNHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRETRP--------RPSQPSS-LAML----DLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCPG---PGRVAKIGDF------------------------------GCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGY-MPYPSKSNQEVLEFV-----TSGG--RMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAII-------------------
43 PsiBlast_CBE 74.9239%-105 - C5 -3LW0 IGF1R_HUMAN B:[3-280] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DVYVPD-EW--EVAREKITMS-R-ELGQGSFGMVYEGVA----------KGVVKDEPE-TRVAIKTVN-E-AAS-M--RERIE---FLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSLRP-------------PP--SLS----KMIQMAGEIADGMAYLNANKFVHRDLAARNCMV---A---EDFTVKIGDFGMTRDIYETD-YYR--------------KG---LLPVRWMSPESLKDGVFTTYSDVWSFGVVLWEIATLAE-QPYQGLSNEQVLRFV-----MEGG--LLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEI-------------------
79 PsiBlast_CBE 74.6935%-126 - C5 -3DZQ A:[26-295] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FAKELDATNISID-K-VVGAGEFGEVCSGRL----------K--LPSKKE-ISVAIKTLKVG-Y-T-E--KQRRD---FLGEASIMGQFDHPNIIRLEGVVTKSKPVMIVTEYMENGSLDSFLRKHDAQFTVI-------------------QLVGMLRGIASGMKYLSDMGYVHRDLAARNILI---N---SNLVCKVSDFGL---------------------------------PIRWTSPEAIAYRKFTSASDVWSYGIVLWEVMSYGE-RPYWEMSNQDVIKAV-----DEGY--RLPPPMDCPAALYQLMLDCWQKDRNNRPKFEQIVSILDKL------------
44 PsiBlast_CBE 74.6639%-104 - C5 -3LW0 IGF1R_HUMAN A:[3-280] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DVYVPD-EW--EVAREKITMS-R-ELGQGSFGMVYEGVA----------KGVVKDEPE-TRVAIKTVN-E-AAS-M--RERIE---FLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSLRP-------------PP--SLS----KMIQMAGEIADGMAYLNANKFVHRDLAARNCMV---A---EDFTVKIGDFGMTRDIYETD-YYR--------------KG---LLPVRWMSPESLKDGVFTTYSDVWSFGVVLWEIATLAE-QPYQGLSNEQVLRFV-----MEGG--LLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEI-------------------
41 PsiBlast_CBE 74.4939%-103 - C5 -3LW0 D:[3-280] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DVYVPD-EW--EVAREKITMS-R-ELGQGSFGMVYEGVA----------KGVVKDEPE-TRVAIKTVN-E-AAS-M--RERIE---FLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSLRP-------------PP--SLS----KMIQMAGEIADGMAYLNANKFVHRDLAARNCMV---A---EDFTVKIGDFGMTRDIYETD-YYR--------------KG---LLPVRWMSPESLKDGVFTTYSDVWSFGVVLWEIATLAE-QPYQGLSNEQVLRFV-----MEGG--LLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEI-------------------
88 PsiBlast_CBE 74.4836%-116 - C5 -3IK3 ABL1_MOUSE B:[9-275] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EMERTDITMK-H-KLGGGQYGEVYEGVW----------KKYSLT------VAVKTLK-E-D-T-M--EV-EE---FLKEAAVMKEIKHPNLVQLLGVCTREPPFYIIIEFMTYGNLLDYLRECN--------------RQEVSAV----VLLYMATQISSAMEYLEKKNFIHRDLAARNCLV---G---ENHLVKVADFGLSR-LMTGD-TYTAH--AGAKF------------PIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGM-SPYPGIDLSQVYELL-----EKDY--RMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSI------
42 PsiBlast_CBE 74.3839%-104 - C5 -3LW0 IGF1R_HUMAN C:[3-280] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DVYVPD-EW--EVAREKITMS-R-ELGQGSFGMVYEGVA----------KGVVKDEPE-TRVAIKTVN-E-AAS-M--RERIE---FLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSLRP-------------PP--SLS----KMIQMAGEIADGMAYLNANKFVHRDLAARNCMV---A---EDFTVKIGDFGMTRDIYETD-YYR--------------KG---LLPVRWMSPESLKDGVFTTYSDVWSFGVVLWEIATLAE-QPYQGLSNEQVLRFV-----MEGG--LLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEI-------------------
86 PsiBlast_CBE 74.1436%-109 - C5 -3OY3 ABL1_MOUSE B:[9-275] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EMERTDITMK-H-KLGGGQYGEV---------------YEGVWKKYS-LTVAVKTLK-E-D-T-M--EV-EE---FLKEAAVMKEIKHPNLVQLLGVCTREPPFYIIIEFMTYGNLLDYLRECN--------------RQEVSAV----VLLYMATQISSAMEYLEKKNFIHRDLAARNCLV---G---ENHLVKVADFGLSR-LMTGD-TYTAH--AGAKF------------PIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGM-SPYPGIDLSQVYELL-----EKDY--RMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSI------
30 PsiBlast_CBE 73.8039%-103 - C5 -3I81 A:[6-283] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DVYVPD-EW--EVAREKITMS-R-ELGQGSFGMVYEGVA----------KGVVKDEPE-TRVAIKTVN-E-AAS-M--RERIE---FLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSLRPE-----ENNPVLAPP--SLS----KMIQMAGEIADGMAYLNANKFVHRDLAARNCMV---A---EDFTVKIGDFGMTRDIYETD-YYR-------------------LLPVRWMSPESLKDGVFTTYSDVWSFGVVLWEIATLAE-QPYQGLSNEQVLRFV-----MEGG--LLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEI-------------------
92 PsiBlast_CBE 73.7535%-114 - C5 -3DK3 ABL1_MOUSE A:[7-273] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EMERTDITMK-H-KLGGGQYGEV---------------YEGVWKKYS-LTVAVKTLK-E---------V-EE---FLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECN--------------RQEVSAV----VLLYMATQISSAMEYLEKKNFIHRDLAARNCLV---G---ENHLVKVADFGLSRLM------------TGDTFT----AHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGM-SPYPGIDPSQVYELL-----EKDY--RMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSI------
108 PsiBlast_CBE 73.7135%-109 - C5 -2G1T ABL1_HUMAN D:[1-277] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHMSPNYD-KW--EMERTDITMK-H-KLGGGQYGEV---------------YEGVWKKYS-LTVAVKTLK-E-D-T-M--EV-EE---FLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECN--------------RQEVNAV----VLLYMATQISSAMEYLEKKNFIHRDLAARNCLV---G---ENHLVKVADFGLSR-LMTGD-TYTAH--AGAKF------------PIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGM-SPYPGIDLSQVYELL-----EKDY--RMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSI------
59 PsiBlast_CBE 73.4938%-109 - C5 -4ANQ A:[24-310] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NPNYCFAGKTSSISD---LKEVPRKNITLI-R-GLG--AFGEVYEGQV------------------P-LQVAVKTL----P-E-V--CSEQDELDFLMEALIISKFNHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRETRP--------RPSQPSS-LAML----DLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCPG---PGRVAKIADFGMARDIYR---------------------GGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGY-MPYPSKSNQEVLEFV-----TSGG--RMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAII-------------------
95 PsiBlast_CBE 73.2936%-123 - C5 -3K5V ABL1_MOUSE B:[14-280] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EMERTDITMK-H-KLGGGQYGEVYEGVW----------KKYSLT------VAVKTLK-------M--EV-EE---FLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECN--------------RQEVSAV----VLLYMATQISSAMEYLEKKNFIHRDLAARNCLV---G---ENHLVKVADFGLSR-LMTGD-TYTAH--AGAKF------------PIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGM-SPYPGIDLSQVYELL-----EKDY--RMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSI------
62 PsiBlast_CBE 73.2938%-114 - C5 -2XB7 A:[3-287] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NYCFAGKTSSISD---LKEVPRKNITLI-R-GLGHGAFGEVYEGQV----------S-------P-LQVAVKTL----P-E-V--CSEQDELDFLMEALIISKFNHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRETRP--------RPSQPS-SLAML----DLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCPG---PGRVAKIGDFGMA-----------------------------AMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGY-MPYPSKSNQEVLEFV-----TSGG--RMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAII-------------------
100 PsiBlast_CBE 73.2736%-113 - C5 -1M52 ABL1_MOUSE B:[14-280] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EMERTDITMK-H-KLGGGQYGEVYEGVW----------KKYSLT------VAVKTLK-E-D-T-M--EV-EE---FLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECN--------------RQEVSAV----VLLYMATQISSAMEYLEKKNFIHRDLAARNCLV---G---ENHLVKVADFGLSR-LMTGD-TYTAH--AGAKF------------PIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGM-SPYPGIDLSQVYELL-----EKDY--RMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSI------