@TOME V2.3
(Nov 2016)

Ref. - - Doc.
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Alignment:

3D Common Core:

Structural Clustering:

Modeller Result :

Complexes Modeling
Templates Information:
Sequence & Result Tab:

Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : PASK_HUMAN: (2013-07-24 )
MEDGGLTAFEEDQRCLSQSLPLPVSAEGPAAQTTAEPSRSFSSAHRHLSRRNGLSRLCQSRTALSEDRWSSYCLSSLAAQNICTSKLHCPAAPEHTDPSEPRGSVSCCSLLRGLSSGWSSPLLPAPVCNPNKAIFTVDAKTTEILVANDKACGLLGYSSQDLIGQKLTQFFLRSDSDVVEALSEEHMEADGHAAVVFGTVVDIISRSGEKIPVSVWMKRMRQERRLCCVVVLEPVERVSTWVAFQSDGTVTSCDSLFAHLHGYVSGEDVAGQHITDLIPSVQLPPSGQHIPKNLKIQRSVGRARDGTTFPLSLKLKSQPSSEEATTGEAAPVSGYRASVWVFCTISGLITLLPDGTIHGINHSFALTLFGYGKTELLGKNITFLIPGFYSYMDLAYNSSLQLPDLASCLDVGNESGCGERTLDPWQGQDPAEGGQDPRINVVLAGGHVVPRDEIRKLMESQDIFTGTQTELIAGGQLLSCLSPQPAPGVDNVPEGSLPVHGEQALPKDQQITALGREEPVAIESPGQDLLGESRSEPVDVKPFASCEDSEAPVPAEDGGSDAGMCGLCQKAQLERMGVSGPSGSDLWAGAAVAKPQAKGQLAGGSLLMHCPCYGSEWGLWWRSQDLAPSPSGMAGLSFGTPTLDEPWLGVENDREELQTCLIKEQLSQLSLAGALDVPHAELVPTECQAVTAPVSSCDLGGRDLCGGCTGSSSACYALATDLPGGLEAVEAQEVDVNSFSWNLKELFFSDQTDQTSSNCSCATSELRETPSSLAVGSDPDVGSLQEQGSCVLDDRELLLLTGTCVDLGQGRRFRESCVGHDPTEPLEVCLVSSEHYAASDRESPGHVPSTLDAGPEDTCPSAEEPRLNVQVTSTPVIVMRGAAGLQREIQEGAYSGSCYHRDGLRLSIQFEVRRVELQGPTPLFCCWLVKDLLHSQRDSAARTRLFLASLPGSTHSTAAELTGPSLVEVLRARPWFEEPPKAVELEGLAACEGEYSQKYSTMSPLGSGAFGFVWTAVDKEKNKEVVVKFIKKEKVLEDCWIEDPKLGKVTLEIAILSRVEHANIIKVLDIFENQGFFQLVMEKHGSGLDLFAFIDRHPRLDEPLASYIFRQLVSAVGYLRLKDIIHRDIKDENIVIAEDFTIKLIDFGSAAYLERGKLFYTFCGTIEYCAPEVLMGNPYRGPELEMWSLGVTLYTLVFEENPFCELEETVEAAIHPPYLVSKELMSLVSGLLQPVPERRTTLEKLVTDPWVTQPVNLADYTWEEVFRVNKPESGVLSAASLEMGNRSLSDVAQAQELCGGPVPGEAPNGQGCLHPGDPRLLTS

Atome Classification :

(71 SA) .........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570.......580.......590.......600.......610.......620.......630.......640.......650.......660.......670.......680.......690.......700.......710.......720.......730.......740.......750.......760.......770.......780.......790.......800.......810.......820.......830.......840.......850.......860.......870.......880.......890.......900.......910.......920.......930.......940.......950.......960.......970.......980.......990.......1000......1010......1020......1030......1040......1050........1060-.........1070......1080......1090......1100......1110......1120.......1130...---...1140.......1150-......1160......1170......1180......1190......1200-----..------....1210--...----..--..-1220......1230......1240---........1250......1260......1270......1280......1290......1300......1310......1320
(Atome) (Ident) (Tito) (Num) (Ligand) (Uniprot) MEDGGLTAFEEDQRCLSQSLPLPVSAEGPAAQTTAEPSRSFSSAHRHLSRRNGLSRLCQSRTALSEDRWSSYCLSSLAAQNICTSKLHCPAAPEHTDPSEPRGSVSCCSLLRGLSSGWSSPLLPAPVCNPNKAIFTVDAKTTEILVANDKACGLLGYSSQDLIGQKLTQFFLRSDSDVVEALSEEHMEADGHAAVVFGTVVDIISRSGEKIPVSVWMKRMRQERRLCCVVVLEPVERVSTWVAFQSDGTVTSCDSLFAHLHGYVSGEDVAGQHITDLIPSVQLPPSGQHIPKNLKIQRSVGRARDGTTFPLSLKLKSQPSSEEATTGEAAPVSGYRASVWVFCTISGLITLLPDGTIHGINHSFALTLFGYGKTELLGKNITFLIPGFYSYMDLAYNSSLQLPDLASCLDVGNESGCGERTLDPWQGQDPAEGGQDPRINVVLAGGHVVPRDEIRKLMESQDIFTGTQTELIAGGQLLSCLSPQPAPGVDNVPEGSLPVHGEQALPKDQQITALGREEPVAIESPGQDLLGESRSEPVDVKPFASCEDSEAPVPAEDGGSDAGMCGLCQKAQLERMGVSGPSGSDLWAGAAVAKPQAKGQLAGGSLLMHCPCYGSEWGLWWRSQDLAPSPSGMAGLSFGTPTLDEPWLGVENDREELQTCLIKEQLSQLSLAGALDVPHAELVPTECQAVTAPVSSCDLGGRDLCGGCTGSSSACYALATDLPGGLEAVEAQEVDVNSFSWNLKELFFSDQTDQTSSNCSCATSELRETPSSLAVGSDPDVGSLQEQGSCVLDDRELLLLTGTCVDLGQGRRFRESCVGHDPTEPLEVCLVSSEHYAASDRESPGHVPSTLDAGPEDTCPSAEEPRLNVQVTSTPVIVMRGAAGLQREIQEGAYSGSCYHRDGLRLSIQFEVRRVELQGPTPLFCCWLVKDLLHSQRDSAARTRLFLASLPGSTHSTAAELTGPSLVEVLRARPWFEEPPKAVELEGLAACEGEYSQKYSTMSPLGSGAFGFVWTAVDKEKNKEVVVKFIKKEKVLEDCWIEDPKLGKVT--LEIAILSRVE----HANIIKVLDIFENQGFFQLVMEKHGSGLDLFAFIDRHPRLDEPLASYIFRQLVSAVGYLRL-KDIIHRDIKDENIVI---AEDF-TIKLIDFGSAAYL-ERGKLFYTFCGTIEYCAPEVLMGNPYRGPELEMWSLGVTLYTLVFEENPF-----CE------LEETVEA---AIH----PP--YL-VSKELMSLVSGLLQPVPERRTT-----LEKLVTDPWVTQPVNLADYTWEEVFRVNKPESGVLSAASLEMGNRSLSDVAQAQELCGGPVPGEAPNGQGCLHPGDPRLLTS
102 PsiBlast_CBE 68.2431% -93 - C1 -3LIJ ? A:[15-297] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YFQGDLQATPGMFITSKKGHLSEMYQRVKKLGS---GEVLLCRDKVTHVERAIKIIRK-----------SSNSKLL--EEVAVLKLLD----HPNIMKLYDFFEDKRNYYLVMECYKGG-ELFDEIIHRMKFNEVDAAVIIKQVLSGVTYLHK-HNIVHRDLKPENLLLESKEKDA-LIKIVDFGLSAVF-ENQKKMKERLGTAYYIAPEVL--RKKYDEKCDVWSIGVILFILLAGYPPFGGQTDQE------ILRKVEK---GKYTFDSPE--WKNVSEGAKDLIKQMLQFDSQRRIS-----AQQALEHPWIKE----------------------------------------------------------------------
45 PsiBlast_CBE 68.0734% -98 - C1 -3R02 PIM1_HUMAN A:[10-263] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISD--WGELPNGTRVP--MEVVLLKKVSSG--FSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHN-CGVLHRDIKDENILI---DLNRGELKLIDFGSGALL--KDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPF-----EH------DEEIIRG---QVF----FR--QR-VSSECQHLIRWCLALRPSDRPT-----FEEIQNHPWM------------------------------------------------------------------------
49 PsiBlast_CBE 66.7934% -99 - C1 -3CXW PIM1_HUMAN A:[38-291] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISD--WGELP--TRVP--MEVVLLKKVSSG--FSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHN-CGVLHRDIKDENILI---DLNRGELKLIDFGSGALL--KDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPF-----EH------DEEIIGG---QVF----FR--QR-VSSECQHLIRWCLALRPSDRPT-----FEEIQNHPWM------------------------------------------------------------------------
101 PsiBlast_CBE 66.4833% -86 - C1 -3HZT ? A:[3-265] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SDRYQRVKKLGSGAYGEVLLCKDKLTGAERAIKIIKKSSV-----TTTSNSGALL--DEVAVLKQLD----HPNIMKLYEFFEDKRNYYLVMEVYRGG-ELFDEIILRQKFSEVDAAVIMKQVLSGTTYLHK-HNIVHRDLKPENLLLESKSRDA-LIKIVDFGLSAHF-EVG--------TAYYIAPEVL--RKKYDEKCDVWSCGVILYILLCGYPPFGGQTDQE------ILKRVEKGKFSFD----PPDWTQ-VSDEAKQLVKLMLTYEPSKRIS-----AEEALNHPWIVK----------------------------------------------------------------------
20 PsiBlast_PDB 66.1534% -99 - C1 -2XIY PIM1_HUMAN A:[25-278] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISD--WGELPNGTRVP--MEVVLLKKVSSG--FSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHN-CGVLHRDIKDENILI---DLNRGELKLIDFGSGALL--KDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPF-----EH------DEEIIRG---QVF----FR--QR-VSSECQHLIRWCLALRPSDRPT-----FEEIQNHPWM------------------------------------------------------------------------
126 HHSearch 66.1331% -92 - C1 -4GV1 AKT1_HUMAN A:[5-277] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVA-----KDEVAHTL--TENRVLQNSR----HPFLTALKYSFQTHDRLCFVME-YANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLML---DKDG-HIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVLEDNDY-GRAVDWWGLGVVMYEMMCGRLPF-----YNQDHEKLFELILME---EIR----FP--RT-LGPEAKSLLSGLLKKDPKQRLGGGSEDAKEIMQHRFFA------GIVWQHVY---------------------------------------------------------
69 PsiBlast_CBE 65.9034% -93 - C1 -2J2I PIM1_HUMAN B:[37-290] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISD--WGELPNGTRVP--MEVVLLKKVSSG--FSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHN-CGVLHRDIKDENILI---DLNRGELKLIDFGSGALL--KDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPF-----EH------DEEIIGG---QVF----FR--QR-VSSECQHLIRWCLALRPSDRPT-----FEEIQNHPWM------------------------------------------------------------------------
57 PsiBlast_CBE 65.5434% -97 - C1 -1YXU PIM1_HUMAN C:[9-262] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISD--WGELPNGTRVP--MEVVLLKKVSSG--FSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHN-CGVLHRDIKDENILI---DLNRGELKLIDFGSGALL--KDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPF-----EH------DEEIIRG---QVF----FR--QR-VSSECQHLIRWCLALRPSDRPT-----FEEIQNHPWM------------------------------------------------------------------------
76 PsiBlast_CBE 65.4434% -98 - C1 -3C4E PIM1_HUMAN D:[5-258] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISD--WGELPNGTRVP--MEVVLLKKVSSG--FSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHN-CGVLHRDIKDENILI---DLNRGELKLIDFGSGALL--KDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPF-----EH------DEEIIRG---QVF----FR--QR-VSSECQHLIRWCLALRPSDRPT-----FEEIQNHPWM------------------------------------------------------------------------
28 PsiBlast_CBE 65.2734% -93 - C1 -4ALW PIM1_HUMAN A:[52-305] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISD--WGELPNGTRVP--MEVVLLKKVSSG--FSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHN-CGVLHRDIKDENILI---DLNRGELKLIDFGSGALL--KDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPF-----EH------DEEIIRG---QVF----FR--QR-VSSECQHLIRWCLALRPSDRPT-----FEEIQNHPWM------------------------------------------------------------------------
67 PsiBlast_CBE 65.2134% -96 - C1 -2BZH PIM1_HUMAN B:[37-290] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISD--WGELPNGTRVP--MEVVLLKKVSSG--FSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHN-CGVLHRDIKDENILI---DLNRGELKLIDFGSGALL--KDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPF-----EH------DEEIIGG---QVF----FR--QR-VSSECQHLIRWCLALRPSDRPT-----FEEIQNHPWM------------------------------------------------------------------------
60 PsiBlast_CBE 65.1834% -95 - C1 -1YXT PIM1_HUMAN A:[9-262] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISD--WGELPNGTRVP--MEVVLLKKVSSG--FSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHN-CGVLHRDIKDENILI---DLNRGELKLIDFGSGALL--KDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPF-----EH------DEEIIRG---QVF----FR--QR-VSSECQHLIRWCLALRPSDRPT-----FEEIQNHPWM------------------------------------------------------------------------
35 PsiBlast_CBE 65.0634%-100 - C1 -4ENY PIM1_HUMAN A:[10-263] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QYQVGPLLGSG-FGSVYSGIRVSDNLPVAIKHVEKDRISD--WG------RVP--MEVVLLKKVSS---FSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHN-CGVLHRDIKDENILI---DLNRGELKLIDFGSGALL--KDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPF-----EH------DEEIIRG---QVF----FR--QR-VSSECQHLIRWCLALRPSDRPT-----FEEIQNHPWM------------------------------------------------------------------------
81 PsiBlast_CBE 64.9034% -95 - C1 -4AS0 PIM1_HUMAN A:[5-258] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISD--WGELPNGTRVP--MEVVLLKKVSSG--FSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHN-CGVLHRDIKDENILI---DLNRGELKLIDFGSGALL--KDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPF-----EH------DEEIIGG---QVF----FR--QR-VSSECQHLIRWCLALRPSDRPT-----FEEIQNHPWM------------------------------------------------------------------------
74 PsiBlast_CBE 64.9034% -94 - C1 -4K0Y PIM1_HUMAN A:[5-258] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISD--WGELPNGTRVP--MEVVLLKKVSSG--FSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHN-CGVLHRDIKDENILI---DLNRGELKLIDFGSGALL--KDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPF-----EH------DEEIIRG---QVF----FR--QR-VSSECQHLIRWCLALRPSDRPT-----FEEIQNHPWM------------------------------------------------------------------------
47 PsiBlast_CBE 64.8934% -95 - C1 -3R00 PIM1_HUMAN A:[10-263] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISD--WGELPNGTRVP--MEVVLLKKVSSG--FSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHN-CGVLHRDIKDENILI---DLNRGELKLIDFGSGALL--KDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPF-----EH------DEEIIRG---QVF----FR--QR-VSSECQHLIRWCLALRPSDRPT-----FEEIQNHPWM------------------------------------------------------------------------
36 PsiBlast_CBE 64.8334% -97 - C1 -4ENX PIM1_HUMAN A:[10-263] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISD--WGEL---TRVP--MEVVLLKKVSSG--FSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHN-CGVLHRDIKDENILI---DLNRGELKLIDFGSGALL--KDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPF-----EH------DEEIIRG---QVF----FR--QR-VSSECQHLIRWCLALRPSDRPT-----FEEIQNHPWM------------------------------------------------------------------------
39 PsiBlast_CBE 64.8034% -95 - C1 -3VC4 PIM1_HUMAN A:[10-263] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISD--WGELPNGTRVP--MEVVLLKKVSSG--FSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHN-CGVLHRDIKDENILI---DLNRGELKLIDFGSGALL--KDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPF-----EH------DEEIIRG---QVF----FR--QR-VSSECQHLIRWCLALRPSDRPT-----FEEIQNHPWM------------------------------------------------------------------------
37 PsiBlast_CBE 64.7634%-100 - C1 -3UMW PIM1_HUMAN A:[10-263] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISD--WGEL----RVP--MEVVLLKKVSSG--FSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHN-CGVLHRDIKDENILI---DLNRGELKLIDFGSGALL--KDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPF-----EH------DEEIIRG---QVF----FR--QR-VSSECQHLIRWCLALRPSDRPT-----FEEIQNHPWM------------------------------------------------------------------------
42 PsiBlast_CBE 64.7534% -97 - C1 -3VBV PIM1_HUMAN A:[10-263] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISD--WGEL---TRVP--MEVVLLKKVSSG--FSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHN-CGVLHRDIKDENILI---DLNRGELKLIDFGSGALL--KDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPF-----EH------DEEIIRG---QVF----FR--QR-VSSECQHLIRWCLALRPSDRPT-----FEEIQNHPWM------------------------------------------------------------------------
59 PsiBlast_CBE 64.6934% -95 - C1 -1YXU PIM1_HUMAN A:[9-262] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISD--WGELPNGTRVP--MEVVLLKKVSSG--FSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHN-CGVLHRDIKDENILI---DLNRGELKLIDFGSGALL--KDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPF-----EH------DEEIIRG---QVF----FR--QR-VSSECQHLIRWCLALRPSDRPT-----FEEIQNHPWM------------------------------------------------------------------------
56 PsiBlast_CBE 64.6034% -93 - C1 -1YXU PIM1_HUMAN D:[9-262] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISD--WGELPNGTRVP--MEVVLLKKVSSG--FSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHN-CGVLHRDIKDENILI---DLNRGELKLIDFGSGALL--KDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPF-----EH------DEEIIRG---QVF----FR--QR-VSSECQHLIRWCLALRPSDRPT-----FEEIQNHPWM------------------------------------------------------------------------
70 PsiBlast_CBE 64.5834% -92 - C1 -3JYA PIM1_HUMAN A:[10-263] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISD--WGELPNGTRVP--MEVVLLKKVSSG--FSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHN-CGVLHRDIKDENILI---DLNRGELKLIDFGSGALL--KDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPF-----EH------DEEIIRG---QVF----FR--QR-VSSECQHLIRWCLALRPSDRPT-----FEEIQNHPWM------------------------------------------------------------------------
48 PsiBlast_CBE 64.5634% -98 - C1 -3CY2 PIM1_HUMAN A:[38-291] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISD--WGELP--TRVP--MEVVLLKKVSSG--FSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHN-CGVLHRDIKDENILI---DLNRGELKLIDFGSGALL--KDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPF-----EH------DEEIIGG---QVF----FR--QR-VSSECQHLIRWCLALRPSDRPT-----FEEIQNHPWM------------------------------------------------------------------------
44 PsiBlast_CBE 64.5334% -94 - C1 -3R04 PIM1_HUMAN A:[10-263] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISD--WGELPNGTRVP--MEVVLLKKVSSG--FSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHN-CGVLHRDIKDENILI---DLNRGELKLIDFGSGALL--KDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPF-----EH------DEEIIRG---QVF----FR--QR-VSSECQHLIRWCLALRPSDRPT-----FEEIQNHPWM------------------------------------------------------------------------
19 PsiBlast_PDB 64.3534% -91 - C1 -1XR1 PIM1_HUMAN A:[24-277] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISD--WGELPNGTRVP--MEVVLLKKVSSG--FSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHN-CGVLHRDIKDENILI---DLNRGELKLIDFGSGALL--KDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPF-----EH------DEEIIRG---QVF----FR--QR-VSSECQHLIRWCLALRPSDRPT-----FEEIQNHPWM------------------------------------------------------------------------
54 PsiBlast_CBE 64.0634% -97 - C1 -1YXX PIM1_HUMAN A:[9-262] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISD--WGELPNGTRVP--MEVVLLKKVSSG--FSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHN-CGVLHRDIKDENILI---DLNRGELKLIDFGSGALL--KDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPF-----EH------DEEIIRG---QVF----FR--QR-VSSECQHLIRWCLALRPSDRPT-----FEEIQNHPWM------------------------------------------------------------------------
55 PsiBlast_CBE 63.8034% -96 - C1 -1YXV PIM1_HUMAN A:[9-262] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISD--WGELPNGTRVP--MEVVLLKKVSSG--FSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHN-CGVLHRDIKDENILI---DLNRGELKLIDFGSGALL--KDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPF-----EH------DEEIIRG---QVF----FR--QR-VSSECQHLIRWCLALRPSDRPT-----FEEIQNHPWM------------------------------------------------------------------------
136 HHSearch 63.7431% -91 - C1 -2Y94 AAPK1_RAT A:[12-274] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RVKIGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRS-----LDVVGKIR--REIQNLKLFR----HPHIIKLYQVISTPSDIFMVME-YVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHR-HMVVHRDLKPENVLL---DAHM-NAKIADFGLSNMM-SDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPF-----DDDHVPTLFKKICDG---IFY----TP--QY-LNPSVISLLKHMLQVDPMKRAT-----IKDIREHEWFKQDL--------------------------------------------------------------------
73 PsiBlast_CBE 63.7334% -90 - C1 -4K18 PIM1_HUMAN A:[6-259] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISD--WGELPNGTRVP--MEVVLLKKVSSG--FSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHN-CGVLHRDIKDENILI---DLNRGELKLIDFGSGALL--KDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPF-----EH------DEEIIRG---QVF----FR--QR-VSSECQHLIRWCLALRPSDRPT-----FEEIQNHPWM------------------------------------------------------------------------
17 PsiBlast_PDB 63.5434% -93 - C1 -2XJ0 PIM1_HUMAN A:[25-278] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISD--WGELPNGTRVP--MEVVLLKKVSSG--FSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHN-CGVLHRDIKDENILI---DLNRGELKLIDFGSGALL--KDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPF-----EH------DEEIIRG---QVF----FR--QR-VSSECQHLIRWCLALRPSDRPT-----FEEIQNHPWM------------------------------------------------------------------------
63 PsiBlast_CBE 63.2834% -92 - C1 -2OI4 PIM1_HUMAN X:[37-290] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISD--WGELPNGTRVP--MEVVLLKKVSSG--FSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHN-CGVLHRDIKDENILI---DLNRGELKLIDFGSGALL--KDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPF-----EH------DEEIIGG---QVF----FR--QR-VSSECQHLIRWCLALRPSDRPT-----FEEIQNHPWM------------------------------------------------------------------------
77 PsiBlast_CBE 63.2134% -93 - C1 -3C4E PIM1_HUMAN C:[5-258] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISD--WGELPNGTRVP--MEVVLLKKVSSG--FSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHN-CGVLHRDIKDENILI---DLNRGELKLIDFGSGALL--KDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPF-----EH------DEEIIRG---QVF----FR--QR-VSSECQHLIRWCLALRPSDRPT-----FEEIQNHPWM------------------------------------------------------------------------
51 PsiBlast_CBE 63.2034% -96 - C1 -2O64 PIM1_HUMAN A:[9-262] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISD--WGELPNGTRVP--MEVVLLKKVSSG--FSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHN-CGVLHRDIKDENILI---DLNRGELKLIDFGSGALL--KDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPF-----EH------DEEIIRG---QVF----FR--QR-VSSECQHLIRWCLALRPSDRPT-----FEEIQNHPWM------------------------------------------------------------------------
46 PsiBlast_CBE 63.2034% -93 - C1 -3R01 PIM1_HUMAN A:[10-263] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISD--WGELPNGTRVP--MEVVLLKKVSSG--FSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHN-CGVLHRDIKDENILI---DLNRGELKLIDFGSGALL--KDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPF-----EH------DEEIIRG---QVF----FR--QR-VSSECQHLIRWCLALRPSDRPT-----FEEIQNHPWM------------------------------------------------------------------------
34 PsiBlast_CBE 63.0834% -91 - C1 -3JPV PIM1_HUMAN A:[38-291] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISD--WGELPNGTRVP--MEVVLLKKVSSG--FSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHN-CGVLHRDIKDENILI---DLNRGELKLIDFGSGALL--KDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPF-----EH------DEEIIGG---QVF----FR--QR-VSSECQHLIRWCLA