@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PTK6_HUMAN: (2013-07-24 )
MVSRDQAHLGPKYVGLWDFKSRTDEELSFRAGDVFHVARKEEQWWWATLLDEAGGAVAQGYVPHNYLAERETVESEPWFFGCISRSEAVRRLQAEGNATGAFLIRVSEKPSADYVLSVRDTQAVRHYKIWRRAGGRLHLNEAVSFLSLPELVNYHRAQSLSHGLRLAAPCRKHEPEPLPHWDDWERPREEFTLCRKLGSGYFGEVFEGLWKDRVQVAIKVISRDNLLHQQMLQSEIQAMKKLRHKHILALYAVVSVGDPVYIITELMAKGSLLELLRDSDEKVLPVSELLDIAWQVAEGMCYLESQNYIHRDLAARNILVGENTLCKVGDFGLARLIKEDVYLSHDHNIPYKWTAPEALSRGHYSTKSDVWSFGILLHEMFSRGQVPYPGMSNHEAFLRVDAGYRMPCPLECPPSVHKLMLTCWCRDPEQRPCFKALRERLSSFTSYENPT
Atome Classification :
(64 SA)
.........10........20........30........40-.-.......50........60........70........80........90........100.......110.......120---.........130.......140.......150.......160.......170......----.-180.......190.......200.......210--------.---......220.....--.-.230.......240-.......250.......260.......270.......280------------.........290.......300.......310.......320--........330.......340..--.--....350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MVSRDQAHLGPKYVGLWDFKSRTDEELSFRAGDVFHVARKE-E-QWWWATLLDEAGGAVAQGYVPHNYLAERETVESEPWFFGCISRSEAVRRLQAEGNATGAFLIRVSEKPSADYVLSVRD-----TQAVRHYKIWRRAGGRLHLNEAVSFLSLPELVNYHRAQSLSHGLRLAAPCRKHEPEPL----P-HWDDWERPREEFTLCRKLGSGYFGEVFEGLWKD--------R---VQVAIKVISRDNLL--H-QQMLQSEIQAMKKL-RHKHILALYAVVSVGDPVYIITELMAKGSLLELLRDSD--------------EKVLPVSELLDIAWQVAEGMCYLESQNYIHRDLAARNILVG---ENTLCKVGDFGLARLIKEDVYLS--H--DHNIPYKWTAPEALSRGHYSTKSDVWSFGILLHEMFSRGQVPYPGMSNHEAFLRVDAGYRMPCPLECPPSVHKLMLTCWCRDPEQRPCFKALRERLSSFTSYENPT
111
HHSearch
84.74
47%
-106
- C3 -
2H8H
1
SRC_HUMAN
A:
[87-525]
-----------
T
F
V
A
L
Y
D
Y
E
S
R
T
E
T
D
L
S
F
K
K
G
E
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Q
I
V
N
N
T
-
E
G
D
W
W
L
A
H
S
L
-
S
T
G
---
Q
T
G
Y
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N
Y
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E
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E
N
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C
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F
D
NAK
G
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V
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H
Y
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F
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A
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H
R
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P
Q
T
Q
----
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K
D
A
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E
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C
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M
G
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W
N
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--------
T
---
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--
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-
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T
--------------
G
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N
Y
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A
A
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I
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---
E
N
L
V
C
K
V
A
D
F
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A
R
L
I
E
D
N
E
Y
T
A
--
R
Q-
G
A
K
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A
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A
A
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Y
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E
D
Y
F
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T
E
P
-
113
HHSearch
80.50
42%
-106
- C3 -
1QCF
1
HCK_HUMAN
A:
[8-445]
---------
R
I
I
V
V
A
L
Y
D
Y
E
A
I
H
H
E
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L
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F
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Q
M
V
V
L
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E
S
-
G
-
E
W
W
K
A
R
S
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A
-
T
R
---
K
E
G
Y
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N
Y
V
A
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E
E
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F
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A
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L
A
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M
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Y
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D
Y
D
PRQ
G
D
T
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K
I
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P
----
W
-
E
K
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A
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E
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G
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G
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F
G
E
V
W
M
A
T
Y
N
K
--------
H
---
T
K
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A
V
K
T
M
K
P
G
S
M
S
--
V
-
E
A
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A
-
E
A
N
V
M
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L
-
Q
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D
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A
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-
K
E
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K
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E
--------------
G
S
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K
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M
A
F
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N
Y
I
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L
R
A
A
N
I
L
V
S
---
A
S
L
V
C
K
I
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A
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E
D
N
E
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T
A
--
R
E-
G
A
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P
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A
P
E
A
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N
F
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W
S
F
G
I
L
L
M
E
I
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Y
P
G
M
S
N
P
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A
L
E
R
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R
M
P
R
P
E
N
C
P
E
E
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M
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N
R
P
E
E
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P
T
F
E
Y
I
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S
V
L
D
D
F
Y
T
A
T
E
--
114
HHSearch
76.33
37%
-108
- C3 -
1OPK
3
ABL1_MOUSE
A:
[44-480]
----------
N
L
F
V
A
L
Y
D
F
V
A
S
G
D
N
T
L
S
I
T
K
G
E
K
L
R
V
L
G
Y
N
H
N
-
G
E
W
C
E
A
Q
T
K
--
N
---
G
Q
G
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N
Y
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H
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R
N
A
A
E
Y
L
L
S
S
--
G
I
N
G
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F
L
V
R
E
S
E
S
S
P
G
Q
R
S
I
S
L
R
Y
-----
E
G
R
V
Y
H
Y
R
I
N
T
A
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G
K
L
Y
V
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E
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L
A
E
L
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H
S
T
V
A
D
G
L
I
T
T
L
H
Y
P
A
P
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R
N
K
P
T
I
YGVS
P
-
N
Y
D
K
W
E
M
E
R
T
D
I
T
M
K
H
K
L
G
G
G
Q
Y
G
E
V
Y
E
G
V
W
K
K
Y-------
S
---
L
T
V
A
V
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T
L
K
E
D
T
M
E
--
V
-
E
E
F
L
K
-
E
A
A
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M
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E
I
-
K
H
P
N
L
V
Q
L
L
G
V
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T
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P
P
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Y
I
I
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E
F
M
T
Y
G
N
L
L
D
Y
L
R
E
C
N
--------------
R
Q
E
V
S
A
V
V
L
L
Y
M
A
T
Q
I
S
S
A
M
E
Y
L
E
K
K
N
F
I
H
R
N
L
A
A
R
N
C
L
V
G
---
E
N
H
L
V
K
V
A
D
F
G
L
S
R
L
M
T
G
D
T
Y
T
A
--
H
A-
G
A
K
F
P
I
K
W
T
A
P
E
S
L
A
Y
N
K
F
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I
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V
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A
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L
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W
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A
T
Y
G
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Y
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E
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D
Y
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E
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C
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E
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A
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S
F
A
E
I
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Q
A
F
E
T
M
F
Q
E
S
---
76
PsiBlast_CBE
73.19
52%
-119
- C3 -
3U4W
4
SRC_CHICK
A:
[2-267]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
E
I
P
R
E
S
L
R
L
E
V
K
L
G
Q
G
C
F
G
E
V
W
M
G
T
W
N
G
--------
T
---
T
R
V
A
I
K
T
L
K
P
G
T
M
S
--
P
-
E
A
F
L
Q
-
E
A
Q
V
M
K
K
L
-
R
H
E
K
L
V
Q
L
Y
A
V
V
S
-
E
E
P
I
Y
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E
Y
M
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K
G
S
L
L
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F
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E
M
--------------
G
K
Y
L
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L
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Q
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M
A
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M
N
Y
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R
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L
R
A
A
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G
---
E
N
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V
C
K
V
A
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F
G
L
A
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I
E
D
N
E
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A
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Q
--
G
A
K
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E
A
A
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Y
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R
M
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E
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E
Y
L
Q
A
F
L
E
D
Y
F
T
S
T
E
P
-
47
PsiBlast_CBE
71.79
52%
-120
- C3 -
3UQG
1
SRC_CHICK
A:
[11-278]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
W
E
I
P
R
E
S
L
R
L
E
V
K
L
G
Q
G
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G
E
V
W
M
G
T
W
N
G
--------
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---
T
R
V
A
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K
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M
S
--
P
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Q
-
E
A
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M
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L
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A
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E
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S
L
L
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F
L
K
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E
M
--------------
G
K
Y
L
R
L
P
Q
L
V
D
M
A
A
Q
I
A
S
G
M
A
Y
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E
R
M
N
Y
V
H
R
D
L
R
A
A
N
I
L
V
G
---
E
N
L
V
C
K
V
A
D
F
G
L
A
R
L
I
----------------
P
I
K
W
T
A
P
E
A
A
L
Y
G
R
F
T
I
K
S
D
V
W
S
F
G
I
L
L
T
E
L
T
T
K
G
R
V
P
Y
P
G
M
V
N
R
E
V
L
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V
E
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G
Y
R
M
P
C
P
P
E
C
P
E
S
L
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L
M
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C
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R
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E
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T
F
E
Y
L
Q
A
F
L
E
D
Y
F
T
S
T
E
P
-
66
PsiBlast_CBE
71.14
52%
-118
- C3 -
2BDJ
1
SRC_HUMAN
A:
[4-267]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
W
E
I
P
R
E
S
L
R
L
E
V
K
L
G
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G
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G
E
V
W
M
G
T
W
N
G
--------
T
---
T
R
V
A
I
K
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L
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P
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M
S
--
P
-
E
A
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E
A
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V
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K
L
-
R
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E
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L
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A
V
V
S
-
E
E
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I
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Y
M
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S
L
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F
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--------------
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K
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L
R
L
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Q
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V
D
M
A
A
Q
I
A
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G
M
A
Y
V
E
R
M
N
Y
V
H
R
D
L
R
A
A
N
I
L
V
G
---
E
N
L
V
C
K
V
A
D
F
G
L
A
R
L
I
E
--------------
F
P
I
K
W
T
A
P
E
A
A
L
Y
G
R
F
T
I
K
S
D
V
W
S
F
G
I
L
L
T
E
L
T
T
K
G
R
V
P
Y
P
G
M
V
N
R
E
V
L
D
Q
V
E
R
G
Y
R
M
P
C
P
P
E
C
P
E
S
L
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D
L
M
C
Q
C
W
R
K
E
P
E
E
R
P
T
F
E
Y
L
Q
A
F
L
E
D
Y
F
T
-----
95
PsiBlast_CBE
70.71
51%
-120
- C3 -
1YOL
2
SRC_HUMAN
B:
[9-275]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
W
E
I
P
R
E
S
L
R
L
E
V
K
L
G
Q
G
--
G
E
V
W
M
G
T
W
N
G
--------
T
---
T
R
V
A
I
K
T
L
K
P
G
T
M
S
--
P
-
E
A
F
L
Q
-
E
A
Q
V
M
K
K
L
-
R
H
E
K
L
V
Q
L
Y
A
V
V
S
-
E
E
P
I
Y
I
V
T
E
Y
M
N
K
G
S
L
L
D
F
L
K
G
E
T
--------------
G
K
Y
L
R
L
P
Q
L
V
D
M
S
A
Q
I
A
S
G
M
A
Y
V
E
R
M
N
Y
V
H
R
D
L
R
A
A
N
I
L
V
G
---
E
N
L
V
C
K
V
A
D
-----------------------
P
I
K
W
T
A
P
E
A
A
L
Y
G
R
F
T
I
K
S
D
V
W
S
F
G
I
L
L
T
E
L
T
T
K
G
R
V
P
Y
P
G
M
V
N
R
E
V
L
D
Q
V
E
R
G
Y
R
M
P
C
P
P
E
C
P
E
S
L
H
D
L
M
C
Q
C
W
R
K
E
P
E
E
R
P
T
F
E
Y
L
Q
A
F
L
E
D
Y
F
T
S
T
E
P
-
90
PsiBlast_CBE
70.42
52%
-129
- C3 -
2QLQ
2
SRC_CHICK
A:
[11-278]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
W
E
I
P
R
E
S
L
R
L
E
V
K
L
G
Q
G
C
F
G
E
V
W
M
G
T
W
N
G
--------
T
---
T
R
V
A
I
K
T
L
-----------------
A
Q
V
M
K
K
L
-
R
H
E
K
L
V
Q
L
Y
A
V
V
S
--
E
P
I
Y
I
V
T
E
Y
M
S
K
G
C
L
L
D
F
L
K
G
E
M
--------------
G
K
Y
L
R
L
P
Q
L
V
D
M
A
A
Q
I
A
S
G
M
A
Y
V
E
R
M
N
Y
V
H
R
D
L
R
A
A
N
I
L
V
G
---
E
N
L
V
C
K
V
A
D
F
----------------------
P
I
K
W
T
A
P
E
A
A
L
Y
G
R
F
T
I
K
S
D
V
W
S
F
G
I
L
L
T
E
L
T
T
K
G
R
V
P
Y
P
G
M
V
N
R
E
V
L
D
Q
V
E
R
G
Y
R
M
P
C
P
P
E
C
P
E
S
L
H
D
L
M
C
Q
C
W
R
K
D
P
E
E
R
P
T
F
E
Y
L
Q
A
F
L
E
D
Y
F
T
S
T
E
P
-
58
PsiBlast_CBE
70.24
52%
-120
- C3 -
3EN4
1
SRC_CHICK
B:
[11-278]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
W
E
I
P
R
E
S
L
R
L
E
V
K
L
G
Q
G
C
F
G
E
V
W
M
G
T
W
N
G
--------
T
---
T
R
V
A
I
K
T
L
K
P
G
T
M
S
--
P
-
E
A
F
L
Q
-
E
A
Q
V
M
K
K
L
-
R
H
E
K
L
V
Q
L
Y
A
V
V
S
-
E
E
P
I
Y
I
V
T
E
Y
M
S
K
G
S
L
L
D
F
L
K
G
E
M
--------------
G
K
Y
L
R
L
P
Q
L
V
D
M
A
A
Q
I
A
S
G
M
A
Y
V
E
R
M
N
Y
V
H
R
D
L
R
A
A
N
I
L
V
G
---
E
N
L
V
C
K
V
A
D
F
G
L
A
R
L
--------------
A
K
F
P
I
K
W
T
A
P
E
A
A
L
Y
G
R
F
T
I
K
S
D
V
W
S
F
G
I
L
L
T
E
L
T
T
K
G
R
V
P
Y
P
G
M
V
N
R
E
V
L
D
Q
V
E
R
G
Y
R
M
P
C
P
P
E
C
P
E
S
L
H
D
L
M
C
Q
C
W
R
K
D
P
E
E
R
P
T
F
E
Y
L
Q
A
F
L
E
D
Y
F
T
S
T
E
P
-
49
PsiBlast_CBE
70.16
52%
-121
- C3 -
3UQF
1
SRC_CHICK
A:
[11-278]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
W
E
I
P
R
E
S
L
R
L
E
V
K
L
G
Q
G
C
F
G
E
V
W
M
G
T
W
N
G
--------
T
---
T
R
V
A
I
K
T
L
K
P
G
T
M
S
--
P
-
E
A
F
L
Q
-
E
A
Q
V
M
K
K
L
-
R
H
E
K
L
V
Q
L
Y
A
V
V
S
-
E
E
P
I
Y
I
V
T
E
Y
M
S
K
G
S
L
L
D
F
L
K
G
E
M
--------------
G
K
Y
L
R
L
P
Q
L
V
D
M
A
A
Q
I
A
S
G
M
A
Y
V
E
R
M
N
Y
V
H
R
D
L
R
A
A
N
I
L
V
G
---
E
N
L
V
C
K
V
A
D
F
G
L
A
-------------------
P
I
K
W
T
A
P
E
A
A
L
Y
G
R
F
T
I
K
S
D
V
W
S
F
G
I
L
L
T
E
L
T
T
K
G
R
V
P
Y
P
G
M
V
N
R
E
V
L
D
Q
V
E
R
G
Y
R
M
P
C
P
P
E
C
P
E
S
L
H
D
L
M
C
Q
C
W
R
K
D
P
E
E
R
P
T
F
E
Y
L
Q
A
F
L
E
D
Y
F
T
S
T
E
P
-
62
PsiBlast_CBE
69.88
52%
-117
- C3 -
3DQX
1
SRC_CHICK
B:
[12-278]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
W
E
I
P
R
E
S
L
R
L
E
V
K
L
G
Q
G
C
F
G
E
V
W
M
G
T
W
N
G
--------
T
---
T
R
V
A
I
K
T
L
K
P
G
T
M
S
--
P
-
E
A
F
L
Q
-
E
A
Q
V
M
K
K
L
-
R
H
E
K
L
V
Q
L
Y
A
V
V
S
-
E
E
P
I
Y
I
V
T
E
Y
M
S
K
G
S
L
L
D
F
L
K
G
E
M
--------------
G
K
Y
L
R
L
P
Q
L
V
D
M
A
A
Q
I
A
S
G
M
A
Y
V
E
R
M
N
Y
V
H
R
D
L
R
A
A
N
I
L
V
G
---
E
N
L
V
C
K
V
A
D
F
G
L
A
R
L
I
E
--------
Q
--
G
A
K
F
P
I
K
W
T
A
P
E
A
A
L
Y
G
R
F
T
I
K
S
D
V
W
S
F
G
I
L
L
T
E
L
T
T
K
G
R
V
P
Y
P
G
M
V
N
R
E
V
L
D
Q
V
E
R
G
Y
R
M
P
C
P
P
E
C
P
E
S
L
H
D
L
M
C
Q
C
W
R
K
D
P
E
E
R
P
T
F
E
Y
L
Q
A
F
L
E
D
Y
F
T
S
T
E
P
-
45
PsiBlast_CBE
69.60
52%
-118
- C3 -
4AGW
3
SRC_CHICK
A:
[11-278]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
W
E
I
P
R
E
S
L
R
L
E
V
K
L
G
Q
G
C
F
G
E
V
W
M
G
T
W
N
G
--------
T
---
T
R
V
A
I
K
T
L
K
P
G
T
M
S
--
P
-
E
A
F
L
Q
-
E
A
Q
V
M
K
K
L
-
R
H
E
K
L
V
Q
L
Y
A
V
V
S
-
E
E
P
I
Y
I
V
T
E
Y
M
S
K
G
S
L
L
D
F
L
K
G
E
M
--------------
G
K
Y
L
R
L
P
Q
L
V
D
M
A
A
Q
I
A
S
G
M
A
Y
V
E
R
M
N
Y
V
H
R
D
L
R
A
A
N
I
L
V
G
---
E
N
L
V
C
K
V
A
D
F
----------------------
P
I
K
W
T
A
P
E
A
A
L
Y
G
R
F
T
I
K
S
D
V
W
S
F
G
I
L
L
T
E
L
T
T
K
G
R
V
P
Y
P
G
M
V
N
R
E
V
L
D
Q
V
E
R
G
Y
R
M
P
C
P
P
E
C
P
E
S
L
H
D
L
M
C
Q
C
W
R
K
D
P
E
E
R
P
T
F
E
Y
L
Q
A
F
L
E
D
Y
F
T
S
T
E
P
-
56
PsiBlast_CBE
69.45
52%
-132
- C3 -
3EN6
1
SRC_CHICK
B:
[11-278]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
W
E
I
P
R
E
S
L
R
L
E
V
K
L
G
Q
--
F
G
E
V
W
M
G
T
W
N
G
--------
T
---
T
R
V
A
I
K
T
L
-----------------
A
Q
V
M
K
K
L
-
R
H
E
K
L
V
Q
L
Y
A
V
V
S
----
I
Y
I
V
T
E
Y
M
S
K
G
S
L
L
D
F
L
K
G
E
M
--------------
G
K
Y
L
R
L
P
Q
L
V
D
M
A
A
Q
I
A
S
G
M
A
Y
V
E
R
M
N
Y
V
H
R
D
L
R
A
A
N
I
L
V
G
---
E
N
L
V
C
K
V
A
D
F
-----------------------
I
K
W
T
A
P
E
A
A
L
Y
G
R
F
T
I
K
S
D
V
W
S
F
G
I
L
L
T
E
L
T
T
K
G
R
V
P
Y
P
G
M
V
N
R
E
V
L
D
Q
V
E
R
G
Y
R
M
P
C
P
P
E
C
P
E
S
L
H
D
L
M
C
Q
C
W
R
K
D
P
E
E
R
P
T
F
E
Y
L
Q
A
F
L
E
D
Y
F
T
S
T
E
P
-
94
PsiBlast_CBE
68.87
52%
-114
- C3 -
3SVV
1
SRC_CHICK
A:
[11-278]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
W
E
I
P
R
E
S
L
R
L
E
V
K
L
G
Q
G
-
F
G
E
V
W
M
G
T
W
N
G
--------
T
---
T
R
V
A
I
K
T
L
K
P
G
T
M
S
--
P
-
E
A
F
L
Q
-
E
A
Q
V
M
K
K
L
-
R
H
E
K
L
V
Q
L
Y
A
V
V
S
-
E
E
P
I
Y
I
V
C
E
Y
M
S
K
G
S
L
L
D
F
L
K
G
E
M
--------------
G
K
Y
L
R
L
P
Q
L
V
D
M
A
A
Q
I
A
S
G
M
A
Y
V
E
R
M
N
Y
V
H
R
D
L
R
A
A
N
I
L
V
G
---
E
N
L
V
C
K
V
A
D
F
G
L
A
R
------------------
P
I
K
W
T
A
P
E
A
A
L
Y
G
R
F
T
I
K
S
D
V
W
S
F
G
I
L
L
T
E
L
T
T
K
G
R
V
P
Y
P
G
M
V
N
R
E
V
L
D
Q
V
E
R
G
Y
R
M
P
C
P
P
E
C
P
E
S
L
H
D
L
M
C
Q
C
W
R
K
D
P
E
E
R
P
T
F
E
Y
L
Q
A
F
L
E
D
Y
F
T
S
T
E
P
-
79
PsiBlast_CBE
68.86
52%
-121
- C3 -
3TZ8
1
SRC_CHICK
B:
[11-278]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
W
E
I
P
R
E
S
L
R
L
E
V
K
L
G
Q
G
C
F
G
E
V
W
M
G
T
W
N
G
--------
T
---
T
R
V
A
I
K
T
L
K
P
G
T
M
S
--
P
-
E
A
F
L
Q
-
E
A
Q
V
M
K
K
L
-
R
H
E
K
L
V
Q
L
Y
A
V
V
S
-
E
E
P
I
Y
I
V
T
E
Y
M
S
K
G
C
L
L
D
F
L
K
G
E
M
--------------
G
K
Y
L
R
L
P
Q
L
V
D
M
A
A
Q
I
A
S
G
M
A
Y
V
E
R
M
N
Y
V
H
R
D
L
R
A
A
N
I
L
V
G
---
E
N
L
V
C
K
V
A
D
F
G
L
------------------
K
F
P
I
K
W
T
A
P
E
A
A
L
Y
G
R
F
T
I
K
S
D
V
W
S
F
G
I
L
L
T
E
L
T
T
K
G
R
V
P
Y
P
G
M
V
N
R
E
V
L
D
Q
V
E
R
G
Y
R
M
P
C
P
P
E
C
P
E
S
L
H
D
L
M
C
Q
C
W
R
K
D
P
E
E
R
P
T
F
E
Y
L
Q
A
F
L
E
D
Y
F
T
S
T
E
P
-
93
PsiBlast_CBE
68.62
52%
-120
- C3 -
2HWO
2
SRC_CHICK
A:
[11-278]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
W
E
I
P
R
E
S
L
R
L
E
V
K
L
G
-
G
C
F
G
E
V
W
M
G
T
W
N
G
--------
T
---
T
R
V
A
I
K
T
L
K
P
----------
F
L
Q
-
E
A
Q
V
M
K
K
L
-
R
H
E
K
L
V
Q
L
Y
A
V
V
S
---
P
I
Y
I
V
T
E
Y
M
S
K
G
C
L
L
D
F
L
K
G
E
M
--------------
G
K
Y
L
R
L
P
Q
L
V
D
M
A
A
Q
I
A
S
G
M
A
Y
V
E
R
M
N
Y
V
H
R
D
L
R
A
A
N
I
L
V
G
---
E
N
L
V
C
K
V
A
D
F
G
---------------------
P
I
K
W
T
A
P
E
A
A
L
Y
G
R
F
T
I
K
S
D
V
W
S
F
G
I
L
L
T
E
L
T
T
K
G
R
V
P
Y
P
G
M
V
N
R
E
V
L
D
Q
V
E
R
G
Y
R
M
P
C
P
P
E
C
P
E
S
L
H
D
L
M
C
Q
C
W
R
K
D
P
E
E
R
P
T
F
E
Y
L
Q
A
F
L
E
D
Y
F
T
S
T
E
P
-
67
PsiBlast_CBE
68.61
52%
-117
- C3 -
2BDF
1
SRC_HUMAN
B:
[4-271]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
W
E
I
P
R
E
S
L
R
L
E
V
K
L
G
Q
G
C
F
G
E
V
W
M
G
T
W
N
G
--------
T
---
T
R
V
A
I
K
T
L
K
P
G
T
M
S
--
P
-
E
A
F
L
Q
-
E
A
Q
V
M
K
K
L
-
R
H
E
K
L
V
Q
L
Y
A
V
V
S
-
E
E
P
I
Y
I
V
T
E
Y
M
S
K
G
S
L
L
D
F
L
K
G
E
T
--------------
G
K
Y
L
R
L
P
Q
L
V
D
M
A
A
Q
I
A
S
G
M
A
Y
V
E
R
M
N
Y
V
H
R
D
L
R
A
A
N
I
L
V
G
---
E
N
L
V
C
K
V
A
D
F
G
L
A
R
L
I
E
------------
A
K
F
P
I
K
W
T
A
P
E
A
A
L
Y
G
R
F
T
I
K
S
D
V
W
S
F
G
I
L
L
T
E
L
T
T
K
G
R
V
P
Y
P
G
M
V
N
R
E
V
L
D
Q
V
E
R
G
Y
R
M
P
C
P
P
E
C
P
E
S
L
H
D
L
M
C
Q
C
W
R
K
E
P
E
E
R
P
T
F
E
Y
L
Q
A
F
L
E
D
Y
F
T
S
T
E
P
-
55
PsiBlast_CBE
68.35
52%
-128
- C3 -
3EN7
1
SRC_CHICK
A:
[11-278]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
W
E
I
P
R
E
S
L
R
L
E
V
K
L
G
Q
---
G
E
V
W
M
G
T
W
N
-------------
T
R
V
A
I
K
T
L
K
P
----------
F
L
Q
-
E
A
Q
V
M
K
K
L
-
R
H
E
K
L
V
Q
L
Y
A
V
V
S
-
E
E
P
I
Y
I
V
T
E
Y
M
S
K
G
S
L
L
D
F
L
K
G
E
M
--------------
G
K
Y
L
R
L
P
Q
L
V
D
M
A
A
Q
I
A
S
G
M
A
Y
V
E
R
M
N
Y
V
H
R
D
L
R
A
A
N
I
L
V
G
---
E
N
L
V
C
K
V
A
D
F
----------------------
P
I
K
W
T
A
P
E
A
A
L
Y
G
R
F
T
I
K
S
D
V
W
S
F
G
I
L
L
T
E
L
T
T
K
G
R
V
P
Y
P
G
M
V
N
R
E
V
L
D
Q
V
E
R
G
Y
R
M
P
C
P
P
E
C
P
E
S
L
H
D
L
M
C
Q
C
W
R
K
D
P
E
E
R
P
T
F
E
Y
L
Q
A
F
L
E
D
Y
F
T
S
T
E
P
-
69
PsiBlast_CBE
67.95
52%
-118
- C3 -
3QLG
1
SRC_CHICK
B:
[11-278]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
W
E
I
P
R
E
S
L
R
L
E
V
K
L
G
Q
G
C
F
G
E
V
W
M
G
T
W
N
G
--------
T
---
T
R
V
A
I
K
-----
T
M
S
--
P
-
E
A
F
L
Q
-
E
A
Q
V
M
K
K
I
-
R
H
E
K
L
V
Q
L
Y
A
V
V
S
-
E
E
P
I
Y
I
V
T
E
Y
M
S
K
G
S
L
L
D
F
L
K
G
E
M
--------------
G
K
Y
L
R
L
P
Q
L
V
D
M
A
A
Q
I
A
S
G
M
A
Y
V
E
R
M
N
Y
V
H
R
D
L
R
A
A
N
I
L
V
G
---
E
N
L
V
C
K
V
A
D
F
G
L
A
R
L
----------------
F
P
I
K
W
T
A
P
E
A
A
L
Y
G
R
F
T
I
K
S
D
V
W
S
F
G
I
L
L
T
E
L
T
T
K
G
R
V
P
Y
P
G
M
V
N
R
E
V
L
D
Q
V
E
R
G
Y
R
M
P
C
P
P
E
C
P
E
S
L
H
D
L
M
C
Q
C
W
R
K
D
P
E
E
R
P
T
F
E
Y
L
Q
A
F
L
E
D
Y
F
T
S
T
E
P
-
46
PsiBlast_CBE
67.88
52%
-120
- C3 -
3UQG
1
SRC_CHICK
B:
[11-278]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
W
E
I
P
R
E
S
L
R
L
E
V
K
L
G
Q
----
E
V
W
M
G
T
W
N
G
--------
T
---
T
R
V
A
I
K
T
L
K
----
S
--
P
-
E
A
F
L
Q
-
E
A
Q
V
M
K
K
L
-
R
H
E
K
L
V
Q
L
Y
A
V
V
S
-
E
E
P
I
Y
I
V
T
E
Y
M
S
K
G
S
L
L
D
F
L
K
G
E
M
--------------
G
K
Y
L
R
L
P
Q
L
V
D
M
A
A
Q
I
A
S
G
M
A
Y
V
E
R
M
N
Y
V
H
R
D
L
R
A
A
N
I
L
V
G
---
E
N
L
V
C
K
V
A
D
F
G
L
A
R
L
I
----------------
P
I
K
W
T
A
P
E
A
A
L
Y
G
R
F
T
I
K
S
D
V
W
S
F
G
I
L
L
T
E
L
T
T
K
G
R
V
P
Y
P
G
M
V
N
R
E
V
L
D
Q
V
E
R
G
Y
R
M
P
C
P
P
E
C
P
E
S
L
H
D
L
M
C
Q
C
W
R
K
D
P
E
E
R
P
T
F
E
Y
L
Q
A
F
L
E
D
Y
F
T
S
T
E
P
-
75
PsiBlast_CBE
67.87
52%
-121
- C3 -
3U51
2
SRC_CHICK
A:
[3-267]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
I
P
R
E
S
L
R
L
E
V
K
L
G
Q
G
C
F
G
E
V
W
M
G
T
W
N
G
--------
T
---
T
R
V
A
I
K
T
L
K
P
G
T
M
S
--
P
-
E
A
F
L
Q
-
E
A
Q
V
M
K
K
L
-
R
H
E
K
L
V
Q
L
Y
A
V
V
S
-
E
E
P
I
Y
I
V
T
E
Y
M
S
K
G
S
L
L
D
F
L
K
G
E
M
--------------
G
K
Y
L
R
L
P
Q
L
V
D
M
A
A
Q
I
A
S
G
M
A
Y
V
E
R
M
N
Y
V
H
R
D
L
R
A
A
N
I
L
V
G
---
E
N
L
V
C
K
V
A
D
F
G
--------------------
F
P
I
K
W
T
A
P
E
A
A
L
Y
G
R
F
T
I
K
S
D
V
W
S
F
G
I
L
L
T
E
L
T
T
K
G
R
V
P
Y
P
G
M
V
N
R
E
V
L
D
Q
V
E
R
G
Y
R
M
P
C
P
P
E
C
P
E
S
L
H
D
L
M
C
Q
C
W
R
K
D
P
E
E
R
P
T
F
E
Y
L
Q
A
F
L
E
D
Y
F
T
S
T
E
P
-
44
PsiBlast_CBE
67.84
52%
-118
- C3 -
4AGW
3
SRC_CHICK
B:
[11-278]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
W
E
I
P
R
E
S
L
R
L
E
V
K
L
G
Q
G
C
F
G
E
V
W
M
G
T
W
N
G
--------
T
---
T
R
V
A
I
K
T
L
K
P
G
T
M
S
--
P
-
E
A
F
L
Q
-
E
A
Q
V
M
K
K
L
-
R
H
E
K
L
V
Q
L
Y
A
V
V
S
-
E
E
P
I
Y
I
V
T
E
Y
M
S
K
G
S
L
L
D
F
L
K
G
E
M
--------------
G
K
Y
L
R
L
P
Q
L
V
D
M
A
A
Q
I
A
S
G
M
A
Y
V
E
R
M
N
Y
V
H
R
D
L
R
A
A
N
I
L
V
G
---
E
N
L
V
C
K
V
A
D
F
----------------------
P
I
K
W
T
A
P
E
A
A
L
Y
G
R
F
T
I
K
S
D
V
W
S
F
G
I
L
L
T
E
L
T
T
K
G
R
V
P
Y
P
G
M
V
N
R
E
V
L
D
Q
V
E
R
G
Y
R
M
P
C
P
P
E
C
P
E
S
L
H
D
L
M
C
Q
C
W
R
K
D
P
E
E
R
P
T
F
E
Y
L
Q
A
F
L
E
D
Y
F
T
S
T
E
P
-
83
PsiBlast_CBE
67.53
52%
-120
- C3 -
3G5D
2
SRC_CHICK
B:
[11-278]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
W
E
I
P
R
E
S
L
R
L
E
V
K
L
G
Q
---
G
E
V
W
M
G
T
W
N
G
--------
T
---
T
R
V
A
I
K
T
L
K
---
M
S
--
P
-
E
A
F
L
Q
-
E
A
Q
V
M
K
K
L
-
R
H
E
K
L
V
Q
L
Y
A
V
V
S
-
E
E
P
I
Y
I
V
T
E
Y
M
S
K
G
C
L
L
D
F
L
K
G
E
M
--------------
G
K
Y
L
R
L
P
Q
L
V
D
M
A
A
Q
I
A
S
G
M
A
Y
V
E
R
M
N
Y
V
H
R
D
L
R
A
A
N
I
L
V
G
---
E
N
L
V
C
K
V
A
D
F
G
L
A
R
L
----------------
F
P
I
K
W
T
A
P
E
A
A
L
Y
G
R
F
T
I
K
S
D
V
W
S
F
G
I
L
L
T
E
L
T
T
K
G
R
V
P
Y
P
G
M
V
N
R
E
V
L
D
Q
V
E
R
G
Y
R
M
P
C
P
P
E
C
P
E
S
L
H
D
L
M
C
Q
C
W
R
K
D
P
E
E
R
P
T
F
E
Y
L
Q
A
F
L
E
D
Y
F
T
S
T
E
P
-
63
PsiBlast_CBE
67.44
52%
-112
- C3 -
3DQX
1
SRC_CHICK
A:
[12-278]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
W
E
I
P
R
E
S
L
R
L
E
V
K
L
G
Q
G
C
F
G
E
V
W
M
G
T
W
N
G
--------
T
---
T
R
V
A
I
K
T
L
K
P
G
T
M
S
--
P
-
E
A
F
L
Q
-
E
A
Q
V
M
K
K
L
-
R
H
E
K
L
V
Q
L
Y
A
V
V
S
-
E
E
P
I
Y
I
V
T
E
Y
M
S
K
G
S
L
L
D
F
L
K
G
E
M
--------------
G
K
Y
L
R
L
P
Q
L
V
D
M
A
A
Q
I
A
S
G
M
A
Y
V
E
R
M
N
Y
V
H
R
D
L
R
A
A
N
I
L
V
G
---
E
N
L
V
C
K
V
A
D
F
G
L
A
R
L
I
E
-----------
G
A
K
F
P
I
K
W
T
A
P
E
A
A
L
Y
G
R
F
T
I
K
S
D
V
W
S
F
G
I
L
L
T
E
L
T
T
K
G
R
V
P
Y
P
G
M
V
N
R
E
V
L
D
Q
V
E
R
G
Y
R
M
P
C
P
P
E
C
P
E
S
L
H
D
L
M
C
Q
C
W
R
K
D
P
E
E
R
P
T
F
E
Y
L
Q
A
F
L
E
D
Y
F
T
S
T
E
P
-
98
PsiBlast_CBE
67.35
51%
-116
- C3 -
3F3W
1
SRC_CHICK
A:
[11-278]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
W
E
I
P
R
E
S
L
R
L
E
V
K
L
G
Q
G
C
F
G
E
V
W
M
G
T
W
N
G
--------
T
---
T
R
V
A
I
K
T
L
K
P
G
T
M
S
--
P
-
E
A
F
L
Q
-
E
A
Q
V
M
K
K
L
-
R
H
E
K
L
V
Q
L
Y
A
V
V
S
-
E
E
P
I
Y
I
V
M
E
Y
M
S
K
G
C
L
L
D
F
L
K
G
E
M
--------------
G
K
Y
L
R
L
P
Q
L
V
D
M
A
A
Q
I
A
S
G
M
A
Y
V
E
R
M
N
Y
V
H
R
D
L
R
A
A
N
I
L
V
G
---
E
N
L
V
C
K
V
A
D
F
G
L
-------------------
F
P
I
K
W
T
A
P
E
A
A
L
Y
G
R
F
T
I
K
S
D
V
W
S
F
G
I
L
L
T
E
L
T
T
K
G
R
V
P
Y
P
G
M
V
N
R
E
V
L
D
Q
V
E
R
G
Y
R
M
P
C
P
P
E
C
P
E
S
L
H
D
L
M
C
Q
C
W
R
K
D
P
E
E
R
P
T
F
E
Y
L
Q
A
F
L
E
D
Y
F
T
S
T
E
P
-
59
PsiBlast_CBE
67.19
52%
-119
- C3 -
3EN4
1
SRC_CHICK
A:
[11-278]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
W
E
I
P
R
E
S
L
R
L
E
V
K
L
G
Q
G
C
F
G
E
V
W
M
G
T
W
N
G
--------
T
---
T
R
V
A
I
K
T
L
K
P
--
M
S
--
P
-
E
A
F
L
Q
-
E
A
Q
V
M
K
K
L
-
R
H
E
K
L
V
Q
L
Y
A
V
V
S
-
E
E
P
I
Y
I
V
T
E
Y
M
S
K
G
S
L
L
D
F
L
K
G
E
M
--------------
G
K
Y
L
R
L
P
Q
L
V
D
M
A
A
Q
I
A
S
G
M
A
Y
V
E
R
M
N
Y
V
H
R
D
L
R
A
A
N
I
L
V
G
---
E
N
L
V
C
K
V
A
D
F
G
--------------------
F
P
I
K
W
T
A
P
E
A
A
L
Y
G
R
F
T
I
K
S
D
V
W
S
F
G
I
L
L
T
E
L
T
T
K
G
R
V
P
Y
P
G
M
V
N
R
E
V
L
D
Q
V
E
R
G
Y
R
M
P
C
P
P
E
C
P
E
S
L
H
D
L
M
C
Q
C
W
R
K
D
P
E
E
R
P
T
F
E
Y
L
Q
A
F
L
E
D
Y
F
T
S
T
E
P
-
48
PsiBlast_CBE
67.09
52%
-119
- C3 -
3UQF
1
SRC_CHICK
B:
[11-278]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
W
E
I
P
R
E
S
L
R
L
E
V
K
L
G
Q
G
C
F
G
E
V
W
M
G
T
W
N
G
--------
T
---
T
R
V
A
I
K
T
---------
P
-
E
A
F
L
Q
-
E
A
Q
V
M
K
K
L
-
R
H
E
K
L
V
Q
L
Y
A
V
V
S
-
E
E
P
I
Y
I
V
T
E
Y
M
S
K
G
S
L
L
D
F
L
K
G
E
M
--------------
G
K
Y
L
R
L
P
Q
L
V
D
M
A
A
Q
I
A
S
G
M
A
Y
V
E
R
M
N
Y
V
H
R
D
L
R
A
A
N
I
L
V
G
---
E
N
L
V
C
K
V
A
D
F
G
---------------------
P
I
K
W
T
A
P
E
A
A
L
Y
G
R
F
T
I
K
S
D
V
W
S
F
G
I
L
L
T
E
L
T
T
K
G
R
V
P
Y
P
G
M
V
N
R
E
V
L
D
Q
V
E
R
G
Y
R
M
P
C
P
P
E
C
P
E
S
L
H
D
L
M
C
Q
C
W
R
K
D
P
E
E
R
P
T
F
E
Y
L
Q
A
F
L
E
D
Y
F
T
S
T
E
P
-
70
PsiBlast_CBE
67.03
52%
-120
- C3 -
3QLG
1
SRC_CHICK
A:
[11-278]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
W
E
I
P
R
E
S
L
R
L
E
V
K
L
G
Q
G
C
F
G
E
V
W
M
G
T
W
N
G
--------
T
---
T
R
V
A
I
K
T
L
K
P
G
T
M
S
--
P
-
E
A
F
L
Q
-
E
A
Q
V
M
K
K
I
-
R
H
E
K
L
V
Q
L
Y
A
V
V
S
-
E
E
P
I
Y
I
V
T
E
Y
M
S
K
G
S
L
L
D
F
L
K
G
E
M
--------------
G
K
Y
L
R
L
P
Q
L
V
D
M
A
A
Q
I
A
S
G
M
A
Y
V
E
R
M
N
Y
V
H
R
D
L
R
A
A
N
I
L
V
G
---
E
N
L
V
C
K
V
A
D
F
G
--------------------
F
P
I
K
W
T
A
P
E
A
A
L
Y
G
R
F
T
I
K
S
D
V
W
S
F
G
I
L
L
T
E
L
T
T
K
G
R
V
P
Y
P
G
M
V
N
R
E
V
L
D
Q
V
E
R
G
Y
R
M
P
C
P
P
E
C
P
E
S
L
H
D
L
M
C
Q
C
W
R
K
D
P
E
E
R
P
T
F
E
Y
L
Q
A
F
L
E
D
Y
F
T
S
T
E
P
-
74
PsiBlast_CBE
66.88
52%
-120
- C3 -
3U51
1
SRC_CHICK
B:
[3-267]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
I
P
R
E
S
L
R
L
E
V
K
L
G
Q
G
C
F
G
E
V
W
M
G
T
W
N
G
--------
T
---
T
R
V
A
I
K
T
L
K
P
G
T
M
S
--
P
-
E
A
F
L
Q
-
E
A
Q
V
M
K
K
L
-
R
H
E
K
L
V
Q
L
Y
A
V
V
S
-
E
E
P
I
Y
I
V
T
E
Y
M
S
K
G
S
L
L
D
F
L
K
G
E
M
--------------
G
K
Y
L
R
L
P
Q
L
V
D
M
A
A
Q
I
A
S
G
M
A
Y
V
E
R
M
N
Y
V
H
R
D
L
R
A
A
N
I
L
V
G
---
E
N
L
V
C
K
V
A
D
F
G
---------------------
P
I
K
W
T
A
P
E
A
A
L
Y
G
R
F
T
I
K
S
D
V
W
S
F
G
I
L
L
T
E
L
T
T
K
G
R
V
P
Y
P
G
M
V
N
R
E
V
L
D
Q
V
E
R
G
Y
R
M
P
C
P
P
E
C
P
E
S
L
H
D
L
M
C
Q
C
W
R
K
D
P
E
E
R
P
T
F
E
Y
L
Q
A
F
L
E
D
Y
F
T
S
T
E
P
-
68
PsiBlast_CBE
66.68
52%
-116
- C3 -
2BDF
1
SRC_HUMAN
A:
[4-271]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
W
E
I
P
R
E
S
L
R
L
E
V
K
L
G
Q
G
C
F
G
E
V
W
M
G
T
W
N
G
--------
T
---
T
R
V
A
I
K
T
L
K
P
G
T
M
S
--
P
-
E
A
F
L
Q
-
E
A
Q
V
M
K
K
L
-
R
H
E
K
L
V
Q
L
Y
A
V
V
S
-
E
E
P
I
Y
I
V
T
E
Y
M
S
K
G
S
L
L
D
F
L
K
G
E
T
--------------
G
K
Y
L
R
L
P
Q
L
V
D
M
A
A
Q
I
A
S
G
M
A
Y
V
E
R
M
N
Y
V
H
R
D
L
R
A
A
N
I
L
V
G
---
E
N
L
V
C
K
V
A
D
F
G
L
A
R
L
I
E
--------------
F
P
I
K
W
T
A
P
E
A
A
L
Y
G
R
F
T
I
K
S
D
V
W
S
F
G
I
L
L
T
E
L
T
T
K
G
R
V
P
Y
P
G
M
V
N
R
E
V
L
D
Q
V
E
R
G
Y
R
M
P
C
P
P
E
C
P
E
S
L
H
D
L
M
C
Q
C
W
R
K
E
P
E
E
R
P
T
F
E
Y
L
Q
A
F
L
E
D
Y
F
T
S
T
E
P
-
54
PsiBlast_CBE
66.51
52%
-118
- C3 -
3F6X
1
SRC_CHICK
B:
[11-278]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
W
E
I
P
R
E
S
L
R
L
E
V
K
L
G
Q
G
C
-
G
E
V
W
M
G
T
W
N
G
--------
T
---
T
R
V
A
I
K
T
L
K
P
G
T
M
S
--
P
-
E
A
F
L
Q
-
E
A
Q
V
M
K
K
L
-
R
H
E
K
L
V
Q
L
Y
A
V
V
S
-
E
E
P
I
Y
I
V
T
E
Y
M
S
K
G
S
L
L
D
F
L
K
G
E
M
--------------
G
K
Y
L
R
L
P
Q
L
V
D
M
A
A
Q
I
A
S
G
M
A
Y
V
E
R
M
N
Y
V
H
R
D
L
R
A
A
N
I
L
V
G
---
E
N
L
V
C
K
V
A
D
F
G
L
A
R
L
I
--------------
K
F
P
I
K
W
T
A
P
E
A
A
L
Y
G
R
F
T
I
K
S
D
V
W
S
F
G
I
L
L
T
E
L
T
T
K
G
R
V
P
Y
P
G
M
V
N
R
E
V
L
D
Q
V
E
R
G
Y
R
M
P
C
P
P
E
C
P
E
S
L
H
D
L
M
C
Q
C
W
R
K
D
P
E
E
R
P
T
F
E
Y
L
Q
A
F
L
E
D
Y
F
T
S
T
E
P
-
85
PsiBlast_CBE
65.84
52%
-119
- C3 -
3F3V
1
SRC_CHICK
A:
[11-278]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
W
E
I
P
R
E
S
L
R
L
E
V
K
L
G
Q
G
C
F
G
E
V
W
M
G
T
W
N
G
--------
T
---
T
R
V
A
I
K
T
L
K
P
G
T
M
S
--
P
-
E
A
F
L
Q
-
E
A
Q
V
M
K
K
L
-
R
H
E
K
L
V
Q
L
Y
A
V
V
S
-
E
E
P
I
Y
I
V
T
E
Y
M
S
K
G
C
L
L
D
F
L
K
G
E
M
--------------
G
K
Y
L
R
L
P
Q
L
V
D
M
A
A
Q
I
A
S
G
M
A
Y
V
E
R
M
N
Y
V
H
R
D
L
R
A
A
N
I
L
V
G
---
E
N
L
V
C
K
V
A
D
F
G
L
-------------------
F
P
I
K
W
T
A
P
E
A
A
L
Y
G
R
F
T
I
K
S
D
V
W
S
F
G
I
L
L
T
E
L
T
T
K
G
R
V
P
Y
P
G
M
V
N
R
E
V
L
D
Q
V
E
R
G
Y
R
M
P
C
P
P
E
C
P
E
S
L
H
D
L
M
C
Q
C
W
R
K
D
P
E
E
R
P
T
F
E
Y
L
Q
A
F
L
E
D
Y
F
T
S
T
E
P
-
96
PsiBlast_CBE
65.81
51%
-116
- C3 -
1YOL
1
SRC_HUMAN
A:
[8-275]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
W
E
I
P
R
E
S
L
R
L
E
V
K
L
G
Q
G
--
G
E
V
W
M
G
T
W
N
G
--------
T
---
T
R
V
A
I
K
T
L
K
P
G
T
M
S
--
P
-
E
A
F
L
Q
-
E
A
Q
V
M
K
K
L
-
R
H
E
K
L
V
Q
L
Y
A
V
V
S
-
E
E
P
I
Y
I
V
T
E
Y
M
N
K
G
S
L
L
D
F
L
K
G
E
T
--------------
G
K
Y
L
R
L
P
Q
L
V
D
M
S
A
Q
I
A
S
G
M
A
Y
V
E
R
M
N
Y
V
H
R
D
L
R
A
A
N
I
L
V
G
---
E
N
L
V
C
K
V
A
D
-----------------------
P
I
K
W
T
A
P
E
A
A
L
Y
G
R
F
T
I
K
S
D
V
W
S
F
G
I
L
L
T
E
L
T
T
K
G
R
V
P
Y
P
G
M
V
N
R
E
V
L
D
Q
V
E
R
G
Y
R
M
P
C
P
P
E
C
P
E
S
L
H
D
L
M
C
Q
C
W
R
K
E
P
E
E
R
P
T
F
E
Y
L
Q
A
F
L
E
D
Y
F
T
S
T
E
P
-
78
PsiBlast_CBE
65.77
52%
-119
- C3 -
3TZ9
1
SRC_CHICK
A:
[11-278]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
W
E
I
P
R
E
S
L
R
L
E
V
K
L
G
Q
G
C
F
G
E
V
W
M
G
T
W
N
G
--------
T
---
T
R
V
A
I
K
T
L
K
P
G
T
M
S
--
P
-
E
A
F
L
Q
-
E
A
Q
V
M
K
K
L
-
R
H
E
K
L
V
Q
L
Y
A
V
V
S
-
E
E
P
I
Y
I
V
T
E
Y
M
S
K
G
C
L
L
D
F
L
K
G
E
M
--------------
G
K
Y
L
R
L
P
Q
L
V
D
M
A
A
Q
I
A
S
G
M
A
Y
V
E
R
M
N
Y
V
H
R
D
L
R
A
A
N
I
L
V
G
---
E
N
L
V
C
K
V
A
D
F
G
L
-------------------
F
P
I
K
W
T
A
P
E
A
A
L
Y
G
R
F
T
I
K
S
D
V
W
S
F
G
I
L
L
T
E
L
T
T
K
G
R
V
P
Y
P
G
M
V
N
R
E
V
L
D
Q
V
E
R
G
Y
R
M
P
C
P
P
E
C
P
E
S
L
H
D
L
M
C
Q
C
W
R
K
D
P
E
E
R
P
T
F
E
Y
L
Q
A
F
L
E
D
Y
F
T
S
T
E
P
-
89
PsiBlast_CBE
65.76
52%
-116
- C3 -
2QLQ
1
SRC_CHICK
B:
[11-278]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
W
E
I
P
R
E
S
L
R
L
E
V
K
L
G
Q
G
C
F
G
E
V
W
M
G
T
W
N
G
--------
T
---
T
R
V
A
I
K
T
L
------------------
Q
V
M
K
K
L
-
R
H
E
K
L
V
Q
L
Y
A
V
V
S
-
E
E
P
I
Y
I
V
T
E
Y
M
S
K
G
C
L
L
D
F
L
K
G
E
M
--------------
G
K
Y
L
R
L
P
Q
L
V
D
M
A
A
Q
I
A
S
G
M
A
Y
V
E
R
M
N
Y
V
H
R
D
L
R
A
A
N
I
L
V
G
---
E
N
L
V
C
K
V
A
D
F
G
L
A
R
------------------
P
I
K
W
T
A
P
E
A
A
L
Y
G
R
F
T
I
K
S
D
V
W
S
F
G
I
L
L
T
E
L
T
T
K
G
R
V
P
Y
P
G
M
V
N
R
E
V
L
D
Q
V
E
R
G
Y
R
M
P
C
P
P
E
C
P
E
S
L
H
D
L
M
C
Q
C
W
R
K
D
P
E
E
R
P
T
F
E
Y
L
Q
A
F
L
E
D
Y
F
T
S
T
E
P
-
82
PsiBlast_CBE
65.70
52%
-117
- C3 -
3TZ7
1
SRC_CHICK
A:
[11-278]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
W
E
I
P
R
E
S
L
R
L
E
V
K
L
G
Q
G
C
F
G
E
V
W
M
G
T
W
N
G
--------
T
---
T
R
V
A
I
K
T
L
K
P
G
T
M
S
--
P
-
E
A
F
L
Q
-
E
A
Q
V
M
K
K
L
-
R
H
E
K
L
V
Q
L
Y
A
V
V
S
-
E
E
P
I
Y
I
V
T
E
Y
M
S
K
G
C
L
L
D
F
L
K
G
E
M
--------------
G
K
Y
L
R
L
P
Q
L
V
D
M
A
A
Q
I
A
S
G
M
A
Y
V
E
R
M
N
Y
V
H
R
D
L
R
A
A
N
I
L
V
G
---
E
N
L
V
C
K
V
A
D
F
G
--------------------
F
P
I
K
W
T
A
P
E
A
A
L
Y
G
R
F
T
I
K
S
D
V
W
S
F
G
I
L
L
T
E
L
T
T
K
G
R
V
P
Y
P
G
M
V
N
R
E
V
L
D
Q
V
E
R
G
Y
R
M
P
C
P
P
E
C
P
E
S
L
H
D
L
M
C
Q
C
W
R
K
D
P
E
E
R
P
T
F
E
Y
L
Q
A
F
L
E
D
Y
F
T
S
T
E
P
-
80
PsiBlast_CBE
65.46
52%
-121
- C3 -
3TZ8
1
SRC_CHICK
A:
[11-278]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
W
E
I
P
R
E
S
L
R
L
E
V
K
L
G
Q
G
C
F
G
E
V
W
M
G
T
W
N
G
--------
T
---
T
R
V
A
I
K
T
L
K
P
G
T
M
S
--
P
-
E
A
F
L
Q
-
E
A
Q
V
M
K
K
L
-
R
H
E
K
L
V
Q
L
Y
A
V
V
S
-
E
E
P
I
Y
I
V
T
E
Y
M
S
K
G
C
L
L
D
F
L
K
G
E
M
--------------
G
K
Y
L
R
L
P
Q
L
V
D
M
A
A
Q
I
A
S
G
M
A
Y
V
E
R
M
N
Y
V
H
R
D
L
R
A
A
N
I
L
V
G
---
E
N
L
V
C
K
V
A
D
F
G
L
-------------------
F
P
I
K
W
T
A
P
E
A
A
L
Y
G
R
F
T
I
K
S
D
V
W
S
F
G
I
L
L
T
E
L
T
T
K
G
R
V
P
Y
P
G
M
V
N
R
E
V
L
D
Q
V
E
R
G
Y
R
M
P
C
P
P
E
C
P
E
S
L
H
D
L
M
C
Q
C
W
R
K
D
P
E
E
R
P
T
F
E
Y
L
Q
A
F
L
E
D
Y
F
T
S
T
E
P
-
73
PsiBlast_CBE
65.35
52%
-117
- C3 -
3OEZ
2
SRC_CHICK
A:
[11-278]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
W
E
I
P
R
E
S
L
R
L
E
V
K
L
G
Q
G
C
F
G
E
V
W
M
G
T
W
N
G
--------
T
---
T
R
V
A
I
K
T
L
K
P
G
T
M
S
--
P
-
E
A
F
L
Q
-
E
A
Q
V
M
K
K
I
-
R
H
E
K
L
V
Q
L
Y
A
V
V
S
-
E
E
P
I
Y
I
V
T
E
Y
M
S
K
G
S
L
L
D
F
L
K
G
E
M
--------------
G
K
Y
L
R
L
P
Q
L
V
D
M
A
A
Q
I
A
S
G
M
A
Y
V
E
R
M
N
Y
V
H
R
D
L
R
A
A
N
I
L
V
G
---
E
N
L
V
C
K
V
A
D
F
G
L
-------------------
F
P
I
K
W
T
A
P
E
A
A
L
Y
G
R
F
T
I
K
S
D
V
W
S
F
G
I
L
L
T
E
L
T
T
K
G
R
V
P
Y
P
G
M
V
N
R
E
V
L
D
Q
V
E
R
G
Y
R
M
P
C
P
P
E
C
P
E
S
L
H
D
L
M
C
Q
C
W
R
K
D
P
E
E
R
P
T
F
E
Y
L
Q
A
F
L
E
D
Y
F
T
S
T
E
P
-
52
PsiBlast_CBE
65.30
52%
-114
- C3 -
3F6X
1
SRC_CHICK
D:
[11-278]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
W
E
I
P
R
E
S
L
R
L
E
V
K
L
G
Q
G
C
F
G
E
V
W
M
G
T
W
N
G
--------
T
---
T
R
V
A
I
K
T
L
K
P
G
T
M
S
--
P
-
E
A
F
L
Q
-
E
A
Q
V
M
K
K
L
-
R
H
E
K
L
V
Q
L
Y
A
V
V
S
-
E
E
P
I
Y
I
V
T
E
Y
M
S
K
G
S
L
L
D
F
L
K
G
E
M
--------------
G
K
Y
L
R
L
P
Q
L
V
D
M
A
A
Q
I
A
S
G
M
A
Y
V
E
R
M
N
Y
V
H
R
D
L
R
A
A
N
I
L
V
G
---
E
N
L
V
C
K
V
A
D
F
G
L
A
R
L
I
E
-------------
K
F
P
I
K
W
T
A
P
E
A
A
L
Y
G
R
F
T
I
K
S
D
V
W
S
F
G
I
L
L
T
E
L
T
T
K
G
R
V
P
Y
P
G
M
V
N
R
E
V
L
D
Q
V
E
R
G
Y
R
M
P
C
P
P
E
C
P
E
S
L
H
D
L
M
C
Q
C
W
R
K
D
P
E
E
R
P
T
F
E
Y
L
Q
A
F
L
E
D
Y
F
T
S
T
E
P
-
72
PsiBlast_CBE
65.22
52%
-114
- C3 -
3OEZ
1
SRC_CHICK
B:
[11-278]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
W
E
I
P
R
E
S
L
R
L
E
V
K
L
G
Q
G
C
F
G
E
V
W
M
G
T
W
N
G
--------
T
---
T
R
V
A
I
K
T
L
K
P
G
T
M
S
--
P
-
E
A
F
L
Q
-
E
A
Q
V
M
K
K
I
-
R
H
E
K
L
V
Q
L
Y
A
V
V
S
-
E
E
P
I
Y
I
V
T
E
Y
M
S
K
G
S
L
L
D
F
L
K
G
E
M
--------------
G
K
Y
L
R
L
P
Q
L
V
D
M
A
A
Q
I
A
S
G
M
A
Y
V
E
R
M
N
Y
V
H
R
D
L
R
A
A
N
I
L
V
G
---
E
N
L
V
C
K
V
A
D
F
G
--------------------
F
P
I
K
W
T
A
P
E
A
A
L
Y
G
R
F
T
I
K
S
D
V
W
S
F
G
I
L
L
T
E
L
T
T
K
G
R
V
P
Y
P
G
M
V
N
R
E
V
L
D
Q
V
E
R
G
Y
R
M
P
C
P
P
E
C
P
E
S
L
H
D
L
M
C
Q
C
W
R
K
D
P
E
E
R
P
T
F
E
Y
L
Q
A
F
L
E
D
Y
F
T
S
T
E
P
-
61
PsiBlast_CBE
65.02
52%
-115
- C3 -
3EL7
1
SRC_CHICK
A:
[11-278]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
W
E
I
P
R
E
S
L
R
L
E
V
K
L
G
Q
G
--
G
E
V
W
M
G
T
W
N
G
--------
T
---
T
R
V
A
I
K
T
L
K
P
-
T
M
S
--
P
-
E
A
F
L
Q
-
E
A
Q
V
M
K
K
L
-
R
H
E
K
L
V
Q
L
Y
A
V
V
S
-
E
--
I
Y
I
V
T
E
Y
M
S
K
G
S
L
L
D
F
L
K
G
E
M
--------------
G
K
Y
L
R
L
P
Q
L
V
D
M
A
A
Q
I
A
S
G
M
A
Y
V
E
R
M
N
Y
V
H
R
D
L
R
A
A
N
I
L
V
G
---
E
N
L
V
C
K
V
A
D
F
G
---------------------
P
I
K
W
T
A
P
E
A
A
L
Y
G
R
F
T
I
K
S
D
V
W
S
F
G
I
L
L
T
E
L
T
T
K
G
R
V
P
Y
P
G
M
V
N
R
E
V
L
D
Q
V
E
R
G
Y
R
M
P
C
P
P
E
C
P
E
S
L
H
D
L
M
C
Q
C
W
R
K
D
P
E
E
R
P
T
F
E
Y
L
Q
A
F
L
E
D
Y
F
T
S
T
E
P
-
53
PsiBlast_CBE
64.97
52%
-114
- C3 -
3F6X
1
SRC_CHICK
C:
[11-278]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
W
E
I
P
R
E
S
L
R
L
E
V
K
L
G
Q
G
C
F
G
E
V
W
M
G
T
W
N
G
--------
T
---
T
R
V
A
I
K
T
L
K
P
------
P
-
E
A
F
L
Q
-
E
A
Q
V
M
K
K
L
-
R
H
E
K
L
V
Q
L
Y
A
V
V
S
-
E
E
P
I
Y
I
V
T
E
Y
M
S
K
G
S
L
L
D
F
L
K
G
E
M
--------------
G
K
Y
L
R
L
P
Q
L
V
D
M
A
A
Q
I
A
S
G
M
A
Y
V
E
R
M
N
Y
V
H
R
D
L
R
A
A
N
I
L
V
G
---
E
N
L
V
C
K
V
A
D
F
G
L
A
R
L
I
E
-------------
K
F
P
I
K
W
T
A
P
E
A
A
L
Y
G
R
F
T
I
K
S
D
V
W
S
F
G
I
L
L
T
E
L
T
T
K
G
R
V
P
Y
P
G
M
V
N
R
E
V
L
D
Q
V
E
R
G
Y
R
M
P
C
P
P
E
C
P
E
S
L
H
D
L
M
C
Q
C
W
R
K
D
P
E
E
R
P
T
F
E
Y
L
Q
A
F
L
E
D
Y
F
T
S
T
E
P
-
57
PsiBlast_CBE
64.65
52%
-119
- C3 -
3EN5
1
SRC_CHICK
A:
[13-278]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
E
I
P
R
E
S
L
R
L
E
V
K
L
G
Q
G
-
F
G
E
V
W
M
G
T
W
N
G
--------
T
---
T
R
V
A
I
K
T
L
------------------
Q
V
M
K
K
L
-
R
H
E
K
L
V
Q
L
Y
A
V
V
S
-
E
E
P
I
Y
I
V
T
E
Y
M
S
K
G
S
L
L
D
F
L
K
G
E
M
--------------
G
K
Y
L
R
L
P
Q
L
V
D
M
A
A
Q
I
A
S
G
M
A
Y
V
E
R
M
N
Y
V
H
R
D
L
R
A
A
N
I
L
V
G
---
E
N
L
V
C
K
V
A
------------------------
P
I
K
W
T
A
P
E
A
A
L
Y
G
R
F
T
I
K
S
D
V
W
S
F
G
I
L
L
T
E
L
T
T
K
G
R
V
P
Y
P
G
M
V
N
R
E
V
L
D
Q
V
E
R
G
Y
R
M
P
C
P
P
E
C
P
E
S
L
H
D
L
M
C
Q
C
W
R
K
D
P
E
E
R
P
T
F
E
Y
L
Q
A
F
L
E
D
Y
F
T
S
T
E
P
-
50
PsiBlast_CBE
64.63
52%
-116
- C3 -
3G6G
2
SRC_CHICK
B:
[11-278]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
W
E
I
P
R
E
S
L
R
L
E
V
K
L
G
Q
G
C
F
G
E
V
W
M
G
T
W
N
G
--------
T
---
T
R
V
A
I
K
T
L
K
P
G
T
M
S
--
P
-
E
A
F
L
Q
-
E
A
Q
V
M
K
K
L
-
R
H
E
K
L
V
Q
L
Y
A
V
V
S
-
E
E
P
I
Y
I
V
T
E
Y
M
S
K
G
S
L
L
D
F
L
K
G
E
M
--------------
G
K
Y
L
R
L
P
Q
L
V
D
M
A
A
Q
I
A
S
G
M
A
Y
V
E
R
M
N
Y
V
H
R
D
L
R
A
A
N
I
L
V
G
---
E
N
L
V
C
K
V
A
D
F
------------------
G
A
K
F
P
I
K
W
T
A
P
E
A
A
L
Y
G
R
F
T
I
K
S
D
V
W
S
F
G
I
L
L
T
E
L
T
T
K
G
R
V
P
Y
P
G
M
V
N
R
E
V
L
D
Q
V
E
R
G
Y
R
M
P
C
P
P
E
C
P
E
S
L
H
D
L
M
C
Q
C
W
R
K
D
P
E
E
R
P
T
F
E
Y
L
Q
A
F
L
E
D
Y
F
T
S
T
E
P
-
71
PsiBlast_CBE
64.55
52%
-120
- C3 -
3QLF
1
SRC_CHICK
A:
[11-278]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
W
E
I
P
R
E
S
L
R
L
E
V
K
L
G
Q
G
C
F
G
E
V
W
M
G
T
W
N
G
--------
T
---
T
R
V
A
I
K
T
L
K
------------
L
Q
-
E
A
Q
V
M
K
K
I
-
R
H
E
K
L
V
Q
L
Y
A
V
V
S
-
E
E
P
I
Y
I
V
T
E
Y
M
S
K
G
S
L
L
D
F
L
K
G
E
M
--------------
G
K
Y
L
R
L
P
Q
L
V
D
M
A
A
Q
I
A
S
G
M
A
Y
V
E
R
M
N
Y
V
H
R
D
L
R
A
A
N
I
L
V
G
---
E
N
L
V
C
K
V
A
D
F
---------------------
F
P
I
K
W
T
A
P
E
A
A
L
Y
G
R
F
T
I
K
S
D
V
W
S
F
G
I
L
L
T
E
L
T
T
K
G
R
V
P
Y
P
G
M
V
N
R
E
V
L
D
Q
V
E
R
G
Y
R
M
P
C
P
P
E
C
P
E
S
L
H
D
L
M
C
Q
C
W
R
K
D
P
E
E
R
P
T
F
E
Y
L
Q
A
F
L
E
D
Y
F
T
S
T
E
P
-
81
PsiBlast_CBE
64.46
52%
-120
- C3 -
3TZ7
1
SRC_CHICK
B:
[11-278]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
W
E
I
P
R
E
S
L
R
L
E
V
K
L
G
Q
G
C
F
G
E
V
W
M
G
T
W
N
G
--------
T
---
T
R
V
A
I
K
T
L
K
P
G
T
M
S
--
P
-
E
A
F
L
Q
-
E
A
Q
V
M
K
K
L
-
R
H
E
K
L
V
Q
L
Y
A
V
V
S
-
E
E
P
I
Y
I
V
T
E
Y
M
S
K
G
C
L
L
D
F
L
K
G
E
M
--------------
G
K
Y
L
R
L
P
Q
L
V
D
M
A
A
Q
I
A
S
G
M
A
Y
V
E
R
M
N
Y
V
H
R
D
L
R
A
A
N
I
L
V
G
---
E
N
L
V
C
K
V
A
D
F
G
--------------------
F
P
I
K
W
T
A
P
E
A
A
L
Y
G
R
F
T
I
K
S
D
V
W
S
F
G
I
L
L
T
E
L
T
T
K
G
R
V
P
Y
P
G
M
V
N
R
E
V
L
D
Q
V
E
R
G
Y
R
M
P
C
P
P
E
C
P
E
S
L
H
D
L
M
C
Q
C
W
R
K
D
P
E
E
R
P
T
F
E
Y
L
Q
A
F
L
E
D
Y
F
T
S
T
E
P
-
88
PsiBlast_CBE
64.33
52%
-116
- C3 -
3F3T
2
SRC_CHICK
A:
[11-278]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
W
E
I
P
R
E
S
L
R
L
E
V
K
L
G
Q
G
C
F
G
E
V
W
M
G
T
W
N
G
--------
T
---
T
R
V
A
I
K
T
L
K
P
G
T
M
S
--
P
-
E
A
F
L
Q
-
E
A
Q
V
M
K
K
L
-
R
H
E
K
L
V
Q
L
Y
A
V
V
S
-
E
E
P
I
Y
I
V
T
E
Y
M
S
K
G
C
L
L
D
F
L
K
G
E
M
--------------
G
K
Y
L
R
L
P
Q
L
V
D
M
A
A
Q
I
A
S
G
M
A
Y
V
E
R
M
N
Y
V
H
R
D
L
R
A
A
N
I
L
V
G
---
E
N
L
V
C
K
V
A
D
F
G
L
-------------------
F
P
I
K
W
T
A
P
E
A
A
L
Y
G
R
F
T
I
K
S
D
V
W
S
F
G
I
L
L
T
E
L
T
T
K
G
R
V
P
Y
P
G
M
V
N
R
E
V
L
D
Q
V
E
R
G
Y
R
M
P
C
P
P
E
C
P
E
S
L
H
D
L
M
C
Q
C
W
R
K
D
P
E
E
R
P
T
F
E
Y
L
Q
A
F
L
E
D
Y
F
T
S
T
E
P
-
77
PsiBlast_CBE
64.22
52%
-120
- C3 -
3TZ9
1
SRC_CHICK
B:
[11-278]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
W
E
I
P
R
E
S
L
R
L
E
V
K
L
G
Q
G
C
F
G
E
V
W
M
G
T
W
N
G
--------
T
---
T
R
V
A
I
K
T
L
K
P
G
T
M
S
--
P
-
E
A
F
L
Q
-
E
A
Q
V
M
K
K
L
-
R
H
E
K
L
V
Q
L
Y
A
V
V
S
-
E
E
P
I
Y
I
V
T
E
Y
M
S
K
G
C
L
L
D
F
L
K
G
E
M
--------------
G
K
Y
L
R
L
P
Q
L
V
D
M
A
A
Q
I
A
S
G
M
A
Y
V
E
R
M
N
Y
V
H
R
D
L
R
A
A
N
I
L
V
G
---
E
N
L
V
C
K
V
A
D
F
---------------------
F
P
I
K
W
T
A
P
E
A
A
L
Y
G
R
F
T
I
K
S
D
V
W
S
F
G
I
L
L
T
E
L
T
T
K
G
R
V
P
Y
P
G
M
V
N
R
E
V
L
D
Q
V
E
R
G
Y
R
M
P
C
P
P
E
C
P
E
S
L
H
D
L
M
C
Q
C
W
R
K
D
P
E
E
R
P
T
F
E
Y
L
Q
A
F
L
E
D
Y
F
T
S
T
E
P
-
84
PsiBlast_CBE
63.97
52%
-117
- C3 -
3F3V
1
SRC_CHICK
B:
[11-278]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
W
E
I
P
R
E
S
L
R
L
E
V
K
L
G
Q
G
C
F
G
E
V
W
M
G
T
W
N
G
--------
T
---
T
R
V
A
I
K
T
L
K
P
G
T
M
S
--
P
-
E
A
F
L
Q
-
E
A
Q
V
M
K
K
L
-
R
H
E
K
L
V
Q
L
Y
A
V
V
S
-
E
E
P
I
Y
I
V
T
E
Y
M
S
K
G
C
L
L
D
F
L
K
G
E
M
--------------
G
K
Y
L
R
L
P
Q
L
V
D
M
A
A
Q
I
A
S
G
M
A
Y
V
E
R
M
N
Y
V
H
R
D
L
R
A
A
N
I
L
V
G
---
E
N
L
V
C
K
V
A
D
F
G
L
-------------------
F
P
I
K
W
T
A
P
E
A
A
L
Y
G
R
F
T
I
K
S
D
V
W
S
F
G
I
L
L
T
E
L
T
T
K
G
R
V
P
Y
P
G
M
V
N
R
E
V
L
D
Q
V
E
R
G
Y
R
M
P
C
P
P
E
C
P
E
S
L
H
D
L
M
C
Q
C
W
R
K
D
P
E
E
R
P
T
F
E
Y
L
Q
A
F
L
E
D
Y
F
T
S
T
E
P
-
87
PsiBlast_CBE
63.74
52%
-116
- C3 -
3F3U
2
SRC_CHICK
A:
[11-278]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
W
E
I
P
R
E
S
L
R
L
E
V
K
L
G
Q
G
C
F
G
E
V
W
M
G
T
W
N
G
--------
T
---
T
R
V
A
I
K
T
L
K
P
G
T
M
S
--
P
-
E
A
F
L
Q
-
E
A
Q
V
M
K
K
L
-
R
H
E
K
L
V
Q
L
Y
A
V
V
S
-
E
E
P
I
Y
I
V
T
E
Y
M
S
K
G
C
L
L
D
F
L
K
G
E
M
--------------
G
K
Y
L
R
L
P
Q
L
V
D
M
A
A
Q
I
A
S
G
M
A
Y
V
E
R
M
N
Y
V
H
R
D
L
R
A
A
N
I
L
V
G
---
E
N
L
V
C
K
V
A
D
F
G
L
-------------------
F
P
I
K
W
T
A
P
E
A
A
L
Y
G
R
F
T
I
K
S
D
V
W
S
F
G
I
L
L
T
E
L
T
T
K
G
R
V
P
Y
P
G
M
V
N
R
E
V
L
D
Q
V
E
R
G
Y
R
M
P
C
P
P
E
C
P
E
S
L
H
D
L
M
C
Q
C
W
R
K
D
P
E
E
R
P
T
F
E
Y
L
Q
A
F
L
E
D
Y
F
T
S
T
E
P
-
97
PsiBlast_CBE
63.66
51%
-119
- C3 -
3F3W
1
SRC_CHICK
B:
[11-278]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
W
E
I
P
R
E
S
L
R
L
E
V
K
L
G
Q
G
C
F
G
E
V
W
M
G
T
W
N
G
--------
T
---
T
R
V
A
I
K
T
L
K
P
G
T
M
S
--
P
-
E
A
F
L
Q
-
E
A
Q
V
M
K
K
L
-
R
H
E
K
L
V
Q
L
Y
A
V
V
S
-
E
E
P
I
Y
I
V
M
E
Y
M
S
K
G
C
L
L
D
F
L
K
G
E
M
--------------
G
K
Y
L
R
L
P
Q
L
V
D
M
A
A
Q
I
A
S
G
M
A
Y
V
E
R
M
N
Y
V
H
R
D
L
R
A
A
N
I
L
V
G
---
E
N
L
V
C
K
V
A
D
F
G
L
-------------------
F
P
I
K
W
T
A
P
E
A
A
L
Y
G
R
F
T
I
K
S
D
V
W
S
F
G
I
L
L
T
E
L
T
T
K
G
R
V
P
Y
P
G
M
V
N
R
E
V
L
D
Q
V
E
R
G
Y
R
M
P
C
P
P
E
C
P
E
S
L
H
D
L
M
C
Q
C
W
R
K
D
P
E
E
R
P
T
F
E
Y
L
Q
A
F
L
E
D
Y
F
T
S
T
E
P
-
51
PsiBlast_CBE
62.57
52%
-115
- C3 -
3G6G
3
SRC_CHICK
A:
[11-278]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
W
E
I
P
R
E
S
L
R
L
E
V
K
L
G
Q
G
C
F
G
E
V
W
M
G
T
W
N
G
--------
T
---
T
R
V
A
I
K
T
L
K
P
G
T
M
S
--
P
-
E
A
F
L
Q
-
E
A
Q
V
M
K
K
L
-
R
H
E
K
L
V
Q
L
Y
A
V
V
S
-
E
E
P
I
Y
I
V
T
E
Y
M
S
K
G
S
L
L
D
F
L
K
G
E
M
--------------
G
K
Y
L
R
L
P
Q
L
V
D
M
A
A
Q
I
A
S
G
M
A
Y
V
E
R
M
N
Y
V
H
R
D
L
R
A
A
N
I
L
V
G
---
E
N
L
V
C
K
V
A
D
F
G
-----------------
G
A
K
F
P
I
K
W
T
A
P
E
A
A
L
Y
G
R
F
T
I
K
S
D
V
W
S
F
G
I
L
L
T
E
L
T
T
K
G
R
V
P
Y
P
G
M
V
N
R
E
V
L
D
Q
V
E
R
G
Y
R
M
P
C
P
P
E
C
P
E
S
L
H
D
L
M
C
Q
C
W
R
K
D
P
E
E
R
P
T
F
E
Y
L
Q
A
F
L
E
D
Y
F
T
S
T
E
P
-
91
PsiBlast_CBE
62.48
52%
-119
- C3 -
2HWP
1
SRC_CHICK
B:
[11-278]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
W
E
I
P
R
E
S
L
R
L
E
V
K
L
G
Q
---
G
E
V
W
M
G
T
W
N
G
--------
T
---
T
R
V
A
I
K
T
L
------------------
Q
V
M
K
K
L
-
R
H
E
K
L
V
Q
L
Y
A
V
V
S
-
E
E
P
I
Y
I
V
T
E
Y
M
S
K
G
C
L
L
D
F
L
K
G
E
M
--------------
G
K
Y
L
R
L
P
Q
L
V
D
M
A
A
Q
I
A
S
G
M
A
Y
V
E
R
M
N
Y
V
H
R
D
L
R
A
A
N
I
L
V
G
---
E
N
L
V
C
K
V
A
-----------------------
F
P
I
K
W
T
A
P
E
A
A
L
Y
G
R
F
T
I
K
S
D
V
W
S
F
G
I
L
L
T
E
L
T
T
K
G
R
V
P
Y
P
G
M
V
N
R
E
V
L
D
Q
V
E
R
G
Y
R
M
P
C
P
P
E
C
P
E
S
L
H
D
L
M
C
Q
C
W
R
K
D
P
E
E
R
P
T
F
E
Y
L
Q
A
F
L
E
D
Y
F
T
S
T
E
P
-
60
PsiBlast_CBE
62.40
52%
-116
- C3 -
3EL8
1
SRC_CHICK
A:
[11-278]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
W
E
I
P
R
E
S
L
R
L
E
V
K
L
G
Q
G
C
F
G
E
V
W
M
G
T
W
N
G
--------
T
---
T
R
V
A
I
K
T
L
K
P
G
T
M
S
--
P
-
E
A
F
L
Q
-
E
A
Q
V
M
K
K
L
-
R
H
E
K
L
V
Q
L
Y
A
V
V
S
-
E
E
P
I
Y
I
V
T
E
Y
M
S
K
G
S
L
L
D
F
L
K
G
E
M
--------------
G
K
Y
L
R
L
P
Q
L
V
D
M
A
A
Q
I
A
S
G
M
A
Y
V
E
R
M
N
Y
V
H
R
D
L
R
A
A
N
I
L
V
G
---
E
N
L
V
C
K
V
A
D
F
G
L
A
R
L
----------------
F
P
I
K
W
T
A
P
E
A
A
L
Y
G
R
F
T
I
K
S
D
V
W
S
F
G
I
L
L
T
E
L
T
T
K
G
R
V
P
Y
P
G
M
V
N
R
E
V
L
D
Q
V
E
R
G
Y
R
M
P
C
P
P
E
C
P
E
S
L
H
D
L
M
C
Q
C
W
R
K
D
P
E
E
R
P
T
F
E
Y
L
Q
A
F
L
E
D
Y
F
T
S
T
E
P
-
130
HHSearch
62.31
36%
-115
- C3 -
2J0J
1
FAK1_CHICK
A:
[378-651]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
M
----
P
-
S
T
R
D
Y
E
I
Q
R
E
R
I
E
L
G
R
C
I
G
E
G
Q
F
G
D
V
H
Q
G
I
Y
M
S
PEN
P
----
A
---
M
A
V
A
I
K
T
C
K
N
C
T
S
D
--
S
V
R
E
K
F
L
Q
E
A
L
T
M
R
Q
F
-
D
H
P
H
I
V
K
L
I
G
V
I
T
-
E
N
P
V
W
I
I
M
E
L
C
T
L
G
E
L
R
S
F
L
Q
V
R
---------------
K
F
S
L
D
L
A
S
L
I
L
Y
A
Y
Q
L
S
T
A
L
A
Y
L
E
S
K
R
F
V
H
R
D
I
A
A
R
N
V
L
V
S
---
S
N
D
C
V
K
L
G
D
F
G
L
S
R
Y
M
E
D
-------------
L
P
I
K
W
M
A
P
E
S
I
N
F
R
R
F
T
S
A
S
D
V
W
M
F
G
V
C
M
W
E
I
L
M
H
G
V
K
P
F
Q
G
V
K
N
N
D
V
I
G
R
I
E
N
G
E
R
L
P
M
P
P
N
C
P
P
T
L
Y
S
L
M
T
K
C
W
A
Y
D
P
S
R
R
P
R
F
T
E
L
K
A
Q
L
S
T
I
L
E
-----
92
PsiBlast_CBE
62.12
52%
-119
- C3 -
2HWO
2
SRC_CHICK
B:
[11-278]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
W
E
I
P
R
E
S
L
R
L
E
V
K
L
G
Q
G
--
G
E
V
W
M
G
T
W
N
G
--------
T
---
T
R
V
A
I
K
T
L
K
-----------------
Q
V
M
K
K
L
-
R
H
E
K
L
V
Q
L
Y
A
V
V
S
-
E
E
P
I
Y
I
V
T
E
Y
M
S
K
G
C
L
L
D
F
L
K
G
E
M
--------------
G
K
Y
L
R
L
P
Q
L
V
D
M
A
A
Q
I
A
S
G
M
A
Y
V
E
R
M
N
Y
V
H
R
D
L
R
A
A
N
I
L
V
G
---
E
N
L
V
C
K
V
A
D
F
----------------------
P
I
K
W
T
A
P
E
A
A
L
Y
G
R
F
T
I
K
S
D
V
W
S
F
G
I
L
L
T
E
L
T
T
K
G
R
V
P
Y
P
G
M
V
N
R
E
V
L
D
Q
V
E
R
G
Y
R
M
P
C
P
P
E
C
P
E
S
L
H
D
L
M
C
Q
C
W
R
K
D
P
E
E
R
P
T
F
E
Y
L
Q
A
F
L
E
D
Y
F
T
S
T
E
P
-
132
HHSearch
61.58
42%
-110
- C3 -
3TT0
1
FGFR1_HUMAN
A:
[54-353]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
E
Y
E
L
----
P
-
E
D
P
R
W
E
L
P
R
D
R
L
V
L
G
K
P
L
G
E
G
A
F
G
Q
V
V
L
A
E
A
I
G
LDKDKPN
R
V
---
T
K
V
A
V
K
M
L
K
S
D
A
T
E
--
K
D
L
S
D
L
I
S
E
M
E
M
M
K
M
I
G
K
H
K
N
I
I
N
L
L
G
A
C
T
Q
D
G
P
L
Y
V
I
V
E
Y
A
S
K
G
N
L
R
E
Y
L
Q
A
R
R
PPGLEYSYNPSHNP
E
E
Q
L
S
S
K
D
L
V
S
C
A
Y
Q
V
A
R
G
M
E
Y
L
A
S
K
K
C
I
H
R
D
L
A
A
R
N
V
L
V
T
---
E
D
N
V
M
K
I
A
D
F
G
L
A
R
D
I
H
H
I
D
Y
Y
K
KT
T
--
N
G
R
L
P
V
K
W
M
A
P
E
A
L
F
D
R
I
Y
T
H
Q
S
D
V
W
S
F
G
V
L
L
W
E
I
F
T
L
G
G
S
P
Y
P
G
V
P
V
E
E
L
F
K
L
L
K
E
G
H
R
M
D
K
P
S
N
C
T
N
E
L
Y
M
M
M
R
D
C
W
H
A
V
P
S
Q
R
P
T
F
K
Q
L
V
E
D
L
D
R
I
V
A
L
----
86
PsiBlast_CBE
61.53
52%
-116
- C3 -
3F3U
1
SRC_CHICK
B:
[11-278]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
W
E
I
P
R
E
S
L
R
L
E
V
K
L
G
Q
G
C
F
G
E
V
W
M
G
T
W
N
G
--------
T
---
T
R
V
A
I
K
T
L
K
P
G
--
S
--
P
-
E
A
F
L
Q
-
E
A
Q
V
M
K
K
L
-
R
H
E
K
L
V
Q
L
Y
A
V
V
S
-
E
E
P
I
Y
I
V
T
E
Y
M
S
K
G
C
L
L
D
F
L
K
G
E
M
--------------
G
K
Y
L
R
L
P
Q
L
V
D
M
A
A
Q
I
A
S
G
M
A
Y
V
E
R
M
N
Y
V
H
R
D
L
R
A
A
N
I
L
V
G
---
E
N
L
V
C
K
V
A
D
F
G
L
-------------------
F
P
I
K
W
T
A
P
E
A
A
L
Y
G
R
F
T
I
K
S
D
V
W
S
F
G
I
L
L
T
E
L
T
T
K
G
R
V
P
Y
P
G
M
V
N
R
E
V
L
D
Q
V
E
R
G
Y
R
M
P
C
P
P
E
C
P
E
S
L
H
D
L
M
C
Q
C
W
R
K
D
P
E
E
R
P
T
F
E
Y
L
Q
A
F
L
E
D
Y
F
T
S
T
E
P
-
122
HHSearch
61.02
36%
-117
- C3 -
4I4E
1
A:
[9-275]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
Y
E
I
Q
R
E
R
I
E
L
G
R
C
I
G
E
G
Q
F
G
D
V
H
Q
G
I
Y
M
S
--------
P
NP
A
L
A
V
A
I
K
T
C
K
N
C
T
S
D
--
S
V
R
E
K
F
L
Q
E
A
L
T
M
R
Q
F
-
D
H
P
H
I
V
K
L
I
G
V
I
T
-
E
N
P
V
W
I
I
M
E
L
C
T
L
G
E
L
R
S
F
L
Q
V
R
---------------
K
Y
S
L
D
L
A
S
L
I
L
Y
A
Y
Q
L
S
T
A
L
A
Y
L
E
S
K
R
F
V
H
R
D
I
A
A
R
N
V
L
V
S
---
S
N
D
C
V
K
L
G
D
F
---------------------
L
P
I
K
W
M
A
P
E
S
I
N
F
R
R
F
T
S
A
S
D
V
W
M
F
G
V
C
M
W
E
I
L
M
H
G
V
K
P
F
Q
G
V
K
N
N
D
V
I
G
R
I
E
N
G
E
R
L
P
M
P
P
N
C
P
P
T
L
Y
S
L
M
T
K
C
W
A
Y
D
P
S
R
R
P
R
F
T
E
L
K
A
Q
L
S
T
I
L
------
120
HHSearch
60.54
36%
-113
* C3 *
4AOJ
1
NTRK1_HUMAN
A:
[33-320]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
C
V
H
H
I
K
R
R
D
I
V
L
K
W
E
L
G
E
G
A
F
G
K
V
F
L
A
E
C
H
N
LLP-----
K
---
M
L
V
A
V
K
A
L
K
E
A
S
E
S
--
A
-
R
Q
D
F
Q
R
E
A
E
L
L
T
M
L
-
Q
H
Q
H
I
V
R
F
F
G
V
C
T
E
G
R
P
L
L
M
V
F
E
Y
M
R
H
G
D
L
N
R
F
L
R
S
H
G
PD------------
P
G
P
L
G
L
G
Q
L
L
A
V
A
S
Q
V
A
A
G
M
V
Y
L
A
G
L
H
F
V
H
R
D
L
A
T
R
N
C
L
V
G
---
Q
G
L
V
V
K
I
G
D
F
G
------------------
T
M
L
P
I
R
W
M
P
P
E
S
I
L
Y
R
K
F
T
T
E
S
D
V
W
S
F
G
V
V
L
W
E
I
F
T
Y
G
K
Q
P
W
Y
Q
L
S
N
T
E
A
I
D
C
I
T
Q
G
R
E
L
E
R
P
R
A
C
P
P
E
V
Y
A
I
M
R
G
C
W
Q
R
E
P
Q
Q
R
H
S
I
K
D
V
H
A
R
L
Q
A
L
A
Q
A
----
64
PsiBlast_CBE
60.43
52%
-115
- C3 -
3D7T
1
SRC_CHICK
B:
[11-278]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
W
E
I
P
R
E
S
L
R
L
E
V
K
L
G
Q
G
C
F
G
E
V
W
M
G
T
W
N
G
--------
T
---
T
R
V
A
I
K
T
L
K
P
G
T
M
S
--
P
-
E
A
F
L
Q
-
E
A
Q
V
M
K
K
L
-
R
H
E
K
L
V
Q
L
Y
A
V
V
S
-
E
E
P
I
Y
I
V
T
E
Y
M
S
K
G
S
L
L
D
F
L
K
G
E
M
--------------
G
K
Y
L
R
L
P
Q
L
V
D
M
A
A
Q
I
A
S
G
M
A
Y
V
E
R
M
N
Y
V
H
R
D
L
R
A
A
N
I
L
V
G
---
E
N
L
V
C
K
V
A
D
F
G
L
A
R
L
I
--------------
K
F
P
I
K
W
T
A
P
E
A
A
L
Y
G
R
F
T
I
K
S
D
V
W
S
F
G
I
L
L
T
E
L
T
T
K
G
R
V
P
Y
P
G
M
V
N
R
E
V
L
D
Q
V
E
R
G
Y
R
M
P
C
P
P
E
C
P
E
S
L
H
D
L
M
C
Q
C
W
R
K
D
P
E
E
R
P
T
F
E
Y
L
Q
A
F
L
E
D
Y
F
T
S
T
E
P
-
100
PsiBlast_CBE
59.55
51%
-114
- C3 -
1YOM
1
SRC_HUMAN
A:
[8-275]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
W
E
I
P
R
E
S
L
R
L
E
V
K
L
G
Q
G
C
F
G
E
V
W
M
G
T
W
N
G
--------
T
---
T
R
V
A
I
K
T
L
K
P
G
T
M
S
--
P
-
E
A
F
L
Q
-
E
A
Q
V
M
K
K
L
-
R
H
E
K
L
V
Q
L
Y
A
V
V
S
-
E
E
P
I
Y
I
V
T
E
Y
M
N
K
G
S
L
L
D
F
L
K
G
E
T
--------------
G
K
Y
L
R
L
P
Q
L
V
D
M
S
A
Q
I
A
S
G
M
A
Y
V
E
R
M
N
Y
V
H
R
D
L
R
A
A
N
I
L
V
G
---
E
N
L
V
C
K
V
A
D
F
----------------------
P
I
K
W
T
A
P
E
A
A
L
Y
G
R
F
T
I
K
S
D
V
W
S
F
G
I
L
L
T
E
L
T
T
K
G
R
V
P
Y
P
G
M
V
N
R
E
V
L
D
Q
V
E
R
G
Y
R
M
P
C
P
P
E
C
P
E
S
L
H
D
L
M
C
Q
C
W
R
K
E
P
E
E
R
P
T
F
E
Y
L
Q
A
F
L
E
D
Y
F
T
S
T
E
P
-
133
HHSearch
58.50
41%
-101
- C3 -
3L9P
4
A:
[62-345]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
S
D
L
K
E
V
P
R
K
N
I
T
L
I
R
G
L
G
H
G
A
F
G
E
V
Y
E
G
Q
V
S
G
---------S
P
-
L
Q
V
A
V
K
T
L
P
E
V
C
S
E
Q
D
E
-
L
D
F
L
-
M
E
A
L
I
I
S
K
F
-
N
H
Q
N
I
V
R
C
I
G
V
S
L
Q
S
L
P
R
F
I
L
L
E
L
M
A
G
G
D
L
K
S
F
L
R
E
T
R
PRPSQ---------
P
S
S
L
A
M
L
D
L
L
H
V
A
R
D
I
A
C
G
C
Q
Y
L
E
E
N
H
F
I
H
R
D
I
A
A
R
N
C
L
L
T
CPG
P
G
R
V
A
K
I
G
D
F
G
M
A
R
D
I
Y
R
A
G
Y
Y
R
--
K
GG
C
A
M
L
P
V
K
W
M
P
P
E
A
F
M
E
G
I
F
T
S
K
T
D
T
W
S
F
G
V
L
L
W
E
I
F
S
L
G
Y
M
P
Y
P
S
K
S
N
Q
E
V
L
E
F
V
T
S
G
G
R
M
D
P
P
K
N
C
P
G
P
V
Y
R
I
M
T
Q
C
W
Q
H
Q
P
E
D
R
P
N
F
A
I
I
L
E
R
I
E
Y
C
T
Q
-----
99
PsiBlast_CBE
57.30
51%
-116
- C3 -
1YOM
1
SRC_HUMAN
B:
[8-275]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
W
E
I
P
R
E
S
L
R
L
E
V
K
L
G
Q
G
C
F
G
E
V
W
M
G
T
W
N
G
--------
T
---
T
R
V
A
I
K
T
L
K
P
G
T
M
S
--
P
-
E
A
F
L
Q
-
E
A
Q
V
M
K
K
L
-
R
H
E
K
L
V
Q
L
Y
A
V
V
S
-
E
E
P
I
Y
I
V
T
E
Y
M
N
K
G
S
L
L
D
F
L
K
G
E
T
--------------
G
K
Y
L
R
L
P
Q
L
V
D
M
S
A
Q
I
A
S
G
M
A
Y
V
E
R
M
N
Y
V
H
R
D
L
R
A
A
N
I
L
V
G
---
E
N
L
V
C
K
V
A
D
F
---------------------
F
P
I
K
W
T
A
P
E
A
A
L
Y
G
R
F
T
I
K
S
D
V
W
S
F
G
I
L
L
T
E
L
T
T
K
G
R
V
P
Y
P
G
M
V
N
R
E
V
L
D
Q
V
E
R
G
Y
R
M
P
C
P
P
E
C
P
E
S
L
H
D
L
M
C
Q
C
W
R
K
E
P
E
E
R
P
T
F
E
Y
L
Q
A
F
L
E
D
Y
F
T
S
T
E
P
-
Add PDB User Result:
(17 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MVSRDQAHLGPKYVGLWDFKSRTDEELSFRAGDVFHVARKEEQWWWATLLDEAGGAVAQGYVPHNYLAERETVESEPWFFGCISRSEAVRRLQAEGNATGAFLIRVSEKPSADYVLSVRDTQAVRHYKIWRRAGGRLHLNEAVSFLSLPELVNYHRAQSLSHGLRLAAPCRKHEPEPLPHWDDWERPREEFTLCRKLGSGYFGEVFEGLWKDRVQVAIKVISRDNLLHQQMLQSEIQAMKKLRHKHILALYAVVSVGDPVYIITELMAKGSLLELLRDSDEKVLPVSELLDIAWQVAEGMCYLESQNYIHRDLAARNILVGENTLCKVGDFGLARLIKEDVYLSHDHNIPYKWTAPEALSRGHYSTKSDVWSFGILLHEMFSRGQVPYPGMSNHEAFLRVDAGYRMPCPLECPPSVHKLMLTCWCRDPEQRPCFKALRERLSSFTSYENPT
134
-
99%
-117
- C3 -
U134
1
A:
[12-448]
-----------
K
Y
V
G
L
W
D
F
K
S
R
T
D
E
E
L
S
F
R
A
G
D
V
F
H
V
A
R
K
E
E
Q
W
W
W
A
T
L
L
E
A
G
----
A
Q
G
Y
V
P
H
N
Y
L
A
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R
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T
V
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S
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W
F
F
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C
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R
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N
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D
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L
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C
F
K
A
L
R
E
R
L
S
S
F
T
S
Y
E
---
135
-
100%
-131
- C3 -
U135
1
A:
[182-450]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
D
W
E
R
P
R
E
E
F
T
L
C
R
K
L
G
S
G
Y
F
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-
G
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L
A
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N
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L
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G
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N
T
L
C
K
V
G
D
F
G
L
---------------
I
P
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K
W
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A
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A
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A
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F
T
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Y
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N
P
-
136
-
100%
-125
- C3 -
U136
1
B:
[182-450]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
D
W
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R
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E
F
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G
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L
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A
A
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L
V
G
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N
T
L
C
K
V
G
D
F
--------------
D
H
N
I
P
Y
K
W
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A
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Y
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N
P
-
137
-
100%
-124
- C3 -
U137
1
B:
[182-450]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
D
W
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R
P
R
E
E
F
T
L
C
R
K
L
G
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G
Y
F
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C
K
V
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D
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G
----------------
I
P
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N
P
-
138
-
100%
-125
- C3 -
U138
1
B:
[182-450]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
D
W
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R
E
E
F
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L
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K
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A
A
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K
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G
D
F
--------------
D
H
N
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N
P
-
139
-
99%
-123
- C3 -
U139
1
A:
[182-450]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
D
W
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R
P
R
E
E
F
T
L
C
R
K
L
G
S
G
--
G
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---
V
Y
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C
K
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F
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-----------------
P
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A
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Y
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N
P
-
140
-
99%
-117
- C3 -
U140
1
A:
[12-448]
-----------
K
Y
V
G
L
W
D
F
K
S
R
T
D
E
E
L
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F
R
A
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A
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K
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W
W
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A
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L
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----
A
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N
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A
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A
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C
F
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A
L
R
E
R
L
S
S
F
T
S
Y
E
---
141
-
100%
-141
- C3 -
U141
1
B:
[182-450]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
D
W
E
R
P
R
E
E
F
T
L
C
R
K
L
G
S
--
F
G
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V
F
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L
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D
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A
I
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V
I
--------------
I
Q
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K
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K
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A
L
Y
A
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----
Y
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D
F
-------------------
Y
K
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A
L
R
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R
L
S
S
F
T
S
Y
E
N
P
-
142
-
100%
-124
- C3 -
U142
1
B:
[182-450]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
D
W
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R
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R
E
E
F
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L
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K
L
G
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G
Y
F
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R
D
L
A
A
R
N
I
L
V
G
E
N
T
L
C
K
V
G
D
F
G
----------------
I
P
Y
K
W
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A
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A
L
S
R
G
H
Y
S
T
K
S
D
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A
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A
L
R
E
R
L
S
S
F
T
S
Y
E
N
P
-
143
-
100%
-131
- C3 -
U143
1
A:
[182-450]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
D
W
E
R
P
R
E
E
F
T
L
C
R
K
L
G
S
G
Y
F
G
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L
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A
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L
L
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-
E
I
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A
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K
K
L
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A
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A
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V
S
-
G
D
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V
Y
I
I
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L
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A
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L
L
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L
L
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D
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D
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V
L
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L
L
D
I
A
W
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V
A
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G
M
C
Y
L
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Y
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L
A
A
R
N
I
L
V
G
E
N
T
L
C
K
V
G
D
F
G
L
---------------
I
P
Y
K
W
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A
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A
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R
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Y
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A
L
R
E
R
L
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S
F
T
S
Y
E
N
P
-
144
-
100%
-141
- C3 -
U144
1
B:
[182-450]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
D
W
E
R
P
R
E
E
F
T
L
C
R
K
L
G
S
--
F
G
E
V
F
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G
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W
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D
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V
Q
V
A
I
K
V
I
--------------
I
Q
A
M
K
K
L
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H
K
H
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L
A
L
Y
A
V
V
S
V
----
Y
I
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L
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A
A
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N
T
L
C
K
V
G
D
F
-------------------
Y
K
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A
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A
L
S
R
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H
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L
R
E
R
L
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S
F
T
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Y
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N
P
-
145
-
100%
-124
- C3 -
U145
1
B:
[182-450]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
D
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R
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-
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A
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L
A
R
L
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--------
H
N
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A
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N
P
-
146
-
99%
-130
- C3 -
U146
1
B:
[182-450]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
D
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R
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A
A
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N
I
L
V
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C
K
V
G
D
F
G
L
N
--------------
I
P
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K
W
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A
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A
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H
Y
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D
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N
P
-
147
-
100%
-126
- C3 -
U147
1
B:
[182-450]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
D
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A
A
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N
I
L
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T
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C
K
V
G
D
F
G
L
---------------
I
P
Y
K
W
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A
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A
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R
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H
Y
S
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D
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R
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Y
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N
P
-
148
-
100%
-126
- C3 -
U148
1
B:
[182-450]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
D
W
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R
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E
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Y
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A
A
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T
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C
K
V
G
D
F
G
L
---------------
I
P
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A
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A
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R
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S
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D
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N
P
-
149
-
100%
-125
- C3 -
U149
1
B:
[182-450]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
D
W
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R
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F
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C
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G
Y
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-
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L
L
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A
A
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N
I
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T
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C
K
V
G
D
F
--------------
D
H
N
I
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R
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T
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Y
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N
P
-
150
-
100%
-141
- C3 -
U150
1
B:
[182-450]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
D
W
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P
R
E
E
F
T
L
C
R
K
L
G
S
--
F
G
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F
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L
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Q
V
A
I
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V
I
--------------
I
Q
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K
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A
L
Y
A
V
V
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V
----
Y
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L
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A
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S
L
L
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L
L
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A
A
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T
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C
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V
G
D
F
-------------------
Y
K
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A
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-