@TOME V2.3
(Nov 2016)

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3D Common Core:

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Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : STK3_HUMAN: (2013-07-25 )
MEQPPAPKSKLKKLSEDSLTKQPEEVFDVLEKLGEGSYGSVFKAIHKESGQVVAIKQVPVESDLQEIIKEISIMQQCDSPYVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLIEDEIATILKSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIGYNCVADIWSLGITSIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDDFTDFVKKCLVKNPEQRATATQLLQHPFIKNAKPVSILRDLITEAMEIKAKRHEEQQRELEEEEENSDEDELDSHTMVKTSVESVGTMRATSTMSEGAQTMIEHNSTMLESDLGTMVINSEDEEEEDGTMKRNATSPQVQRPSFMDYFDKQDFKNKSHENCNQNMHEPFPMSKNVFPDNWKVPQDGDFDFLKNLSLEELQMRLKALDPMMEREIEELRQRYTAKRQPILDAMDAKKRRQQNF

Atome Classification :

(77 SA) .........10.--.......20.---------.......-------30........40........50.-.......60---..--.-..----..---.70..-......80........90........100....---...110-------.---......120--.......130.....-..-140.-......150....-..-.160......------.170.......180.......190.-----..-.--...200.......210......----.220---------.---.-.-..-..230---........240-----------------...-------.--....250.......260.......270......-.--280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490
(Atome) (Ident) (Tito) (Num) (Ligand) (Uniprot) MEQPPAPKSKLK--KLSEDSLTKQ---------PEEVFDV-------LEKLGEGSYGSVFKAIHKESGQV-VAIKQVPVE---SD--L-QE----II---KEISI-MQQCDSPYVVKYYGSYFKNTDLWIVMEYCGAGS---VSDIIR-------L---RNKTLIEDE--IATILKSTLKGLEYL-HF-MRKI-HRDIKAGNILLNT-EG-HAKLADFGVA------GQLTDTMAKRNTVIGTPFWMAPEVI-----QE-I--GYNCVADIWSLGITSIEMAEGK----PPYA---------D---I-H-PM-RAIF----MIPTNPPPTF------------------RKP-------E--LWSDDFTDFVKKCLVKNPEQRATATQLLQHPFI-K--NAKPVSILRDLITEAMEIKAKRHEEQQRELEEEEENSDEDELDSHTMVKTSVESVGTMRATSTMSEGAQTMIEHNSTMLESDLGTMVINSEDEEEEDGTMKRNATSPQVQRPSFMDYFDKQDFKNKSHENCNQNMHEPFPMSKNVFPDNWKVPQDGDFDFLKNLSLEELQMRLKALDPMMEREIEELRQRYTAKRQPILDAMDAKKRRQQNF
27 PsiBlast_CBE 78.1844%-100 - C4 -4AOT STK10_HUMAN B:[17-295] ---------------------------------PNEVWEI-------VGELGDGAFGKVYKAKNKETGAL-AAAKVIETK---SEEEL-ED----YI---VEIEI-LATCDHPYIVKLLGAYYHDGKLWIMIEFCPGGA---VDAIML-------E---LDRGLTEPQ--IQVVCRQMLEALNFL-HS-KRII-HRDLKAGNVLMTL-EG-DIRLADFGVS------AK-----------IGTPYWMAPEVVM----------PYDYKADIWSLGITLIEMAQIE----PPHH---------E---L-N-PM-RVLL----KIAKSDPPTL------------------LTP-------S--KWSVEFRDFLKIALDKNPETRPSAAQLLEHPFV-S--SITSNKALRELVAEA-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
111 HHSearch 78.0738% -95 - C4 -4FIE PAK4_HUMAN A:[146-419] ---------------------PGD---------PRSYLDN-------FIKIGEGSTGIVCIATVRSSGKL-VAVKKMDLRKQ-QR--R-EL----LF---NEVVI-MRDYQHENVVEMYNSYLVGDELWVVMEFLEGGA---LTDIVT------------HTRMNEEQ--IAAVCLAVLQALSVL-HA-QGVI-HRDIKSDSILLTH-DG-RVKLSDFGFC------AQVSKEVPRRKSLVGTPYWMAPELI-----SR-L--PYGPEVDIWSLGIMVIEMVDGE----PPYF---------N---E-P-PL-KAMK----MIRDNLPPRL------------------KNL-------H--KVSPSLKGFLDRLLVRDPAQRATAAELLKHPFL-A--KAGPPASIVPLMRQ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10 PsiBlast_PDB 77.0354% -91 - C4 -3CKX STK24_HUMAN A:[5-283] ---------------------------------PEELFTK-------LEKIGKGSFGEVFKGIDNRTQKV-VAIKIIDLE---E-----DE----IEDIQQEITV-LSQCDSPYVTKYYGSYLKDTKLWIIMEYLGGGS---ALDL---------L---EPGPLDETQ--IATILREILKGLDYL-HS-EKKI-HRDIKAANVLLSE-HG-EVKLADFGVA------GQLTDTQIKRNTFVGTPFWMAPEVI-----KQ-S--AYDSKADIWSLGITAIELARGE----PPHS---------E---L-H-PM-KVLF----LIPKNNPPTL------------------EGN-----------YSKPLKEFVEACLNKEPSFRPTAKELLKHKFILR--NAKKTSYLTELIDRYKRWKAEQ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8 PsiBlast_PDB 76.9854% -90 - C4 -3A7I STK24_HUMAN A:[15-298] -------------------NLKAD---------PEELFTK-------LEKIGKGSFGEVFKGIDNRTQKV-VAIKIIDLE---EA--E-DE----IEDIQQEITV-LSQCDSPYVTKYYGSYLKDTKLWIIMEYLGGGS---ALDL---------L---EPGPLDETQ--IATILREILKGLDYL-HS-EKKI-HRDIKAANVLLSE-HG-EVKLADFGVA------GQLTDTQIKRNTFVGTPFWMAPEVI-----KQ-S--AYDSKADIWSLGITAIELARGE----PPHS---------E---L-H-PM-KVLF----LIPKNNPPTL------------------EGN-----------YSKPLKEFVEACLNKEPSFRPTAKELLKHKFILR--NAKKTSYLTELIDRYKRWKAEQ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7 PsiBlast_PDB 76.9154% -88 - C4 -3A7H STK24_HUMAN A:[15-298] -------------------NLKAD---------PEELFTK-------LEKIGKGSFGEVFKGIDNRTQKV-VAIKIIDLE---EA--E-DE----IEDIQQEITV-LSQCDSPYVTKYYGSYLKDTKLWIIMEYLGGGS---ALDL---------L---EPGPLDETQ--IATILREILKGLDYL-HS-EKKI-HRDIKAANVLLSE-HG-EVKLADFGVA------GQLTDTQIKRNTFVGTPFWMAPEVI-----KQ-S--AYDSKADIWSLGITAIELARGE----PPHS---------E---L-H-PM-KVLF----LIPKNNPPTL------------------EGN-----------YSKPLKEFVEACLNKEPSFRPTAKELLKHKFILR--NAKKTSYLTELIDRYKRWKAEQ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12 PsiBlast_PDB 76.3955% -97 - C4 -4FZD MST4_HUMAN B:[6-282] ---------------------------------PEELFTK-------LERIGKGSFGEVFKGIDNRTQQV-VAIKIIDLE---EA--E-DE----IEDIQQEITV-LSQCDSSYVTKYYGSYLKGSKLWIIMEYLGGGS---ALDL---------L---RAGPFDEFQ--IATMLKEILKGLDYL-HS-EKKI-HRDIKAANVLLSE-QG-DVKLAAFGVA------GQLT------NTFVGTPFWMAPEVI-----QQ-S--AYDSKADIWSLGITAIELAKGE----PPNS---------D---M-H-PM-RVLF----LIPKNNPPTL------------------VGD-----------FTKSFKEFIDACLNKDPSFRPTAKELLKHKFIVK--NSKKTSYLTELIDRFKRWKA------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9 PsiBlast_PDB 76.3454% -91 - C4 -3A7J STK24_HUMAN A:[15-298] -------------------NLKAD---------PEELFTK-------LEKIGKGSFGEVFKGIDNRTQKV-VAIKIIDLE---EA--E-DE----IEDIQQEITV-LSQCDSPYVTKYYGSYLKDTKLWIIMEYLGGGS---ALDL---------L---EPGPLDETQ--IATILREILKGLDYL-HS-EKKI-HRDIKAANVLLSE-HG-EVKLADFGVA------GQLTDTQIKRNTFVGTPFWMAPEVI-----KQ-S--AYDSKADIWSLGITAIELARGE----PPHS---------E---L-H-PM-KVLF----LIPKNNPPTL------------------EGN-----------YSKPLKEFVEACLNKEPSFRPTAKELLKHKFILR--NAKKTSYLTELIDRYKRWKAEQ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17 PsiBlast_PDB 75.9544%-103 - C4 -4AOT STK10_HUMAN A:[17-295] ---------------------------------PNEVWEI-------VGELGDGAFGKVYKAKNKETGAL-AAAKVIETK---SEEEL-ED----YI---VEIEI-LATCDHPYIVKLLGAYYHDGKLWIMIEFCPGGA---VDAIML-------E---LDRGLTEPQ--IQVVCRQMLEALNFL-HS-KRII-HRDLKAGNVLMTL-EG-DIRLADFGVS------A-------------GTPYWMAPEVVM-----------YDYKADIWSLGITLIEMAQIE----PPHH---------E---L-N-PM-RVLL----KIAKSDPPTL------------------LTP-------S--KWSVEFRDFLKIALDKNPETRPSAAQLLEHPFV-S--SITSNKALRELVAEA-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21 PsiBlast_CBE 74.5855% -97 - C4 -3GGF MST4_HUMAN B:[21-298] ---------------------------------PEELFTK-------LERIGKGSFGEVFKGIDNRTQQV-VAIKIIDLE---EA--E-DE----IEDIQQEITV-LSQCDSSYVTKYYGSYLKGSKLWIIMEYLGGGS---ALDL---------L---RAGPFDEFQ--IATMLKEILKGLDYL-HS-EKKI-HRDIKAANVLLSE-QG-DVKLADFGVA----------------NTFVGTPFWMAPEVI-----QQ-S--AYDSKADIWSLGITAIELAKGE----PPNS---------D---M-H-PM-RVLF----LIPKNNPPTL------------------VGD-----------FTKSFKEFIDACLNKDPSFRPTAKELLKHKFIVK--NSKKTSYLTELIDRFKRWKAE-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
129 HHSearch 74.4943% -96 - C4 -3FXZ ? A:[7-293] -----------E--KLRSIVSVGD---------PKKKYTR-------FEKIGQGASGTVYTAMDVATGQE-VAIRQMNLQQQ-PK--K-EL----II---NEILV-MRENKNPNIVNYLDSYLVGDELWVVMEYLAGGS---LTDVVT------------ETCMDEGQ--IAAVCRECLQALEFL-HS-NQVI-HRDIKSDNILLGM-DG-SVKLTDFGFC------AQITPEQSKRSTMVGTPYWMAPEVV-----TR-K--AYGPKVDIWSLGIMAIEMIEGE----PPYL---------N---E-N-PL-RALY----LIATNGTPEL------------------QNP-------E--KLSAIFRDFLNRCLEMDVEKRGSAKELLQHQFL-K--IAKPLSSLTPLIAAAKEAT-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2 PsiBlast_PDB 74.4455% -96 - C4 -3GGF MST4_HUMAN A:[21-300] ---------------------------------PEELFTK-------LERIGKGSFGEVFKGIDNRTQQV-VAIKIIDLE---EA--E-DE----IEDIQQEITV-LSQCDSSYVTKYYGSYLKGSKLWIIMEYLGGGS---ALDL---------L---RAGPFDEFQ--IATMLKEILKGLDYL-HS-EKKI-HRDIKAANVLLSE-QG-DVKLADFGVA---------------RNTFVGTPFWMAPEVI-----QQ-S--AYDSKADIWSLGITAIELAKGE----PPNS---------D---M-H-PM-RVLF----LIPKNNPPTL------------------VGD-----------FTKSFKEFIDACLNKDPSFRPTAKELLKHKFIVK--NSKKTSYLTELIDRFKRWKAEGH---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13 PsiBlast_PDB 74.3355% -86 - C4 -4FZF ? B:[6-282] ---------------------------------PEELFTK-------LERIGKG--GEVFKGIDNRTQQV-VAIKIIDLE---EA--E-DE----IEDIQQEITV-LSQCDSSYVTKYYGSYLKGSKLWIIMEYLGGGS---ALDL---------L---RAGPFDEFQ--IATMLKEILKGLDYL-HS-EKKI-HRDIKAANVLLSE-QG-DVKLAAFGVA------GQLTDTQIKRNTFVGTPFWMAPEVI-----QQ-S--AYDSKADIWSLGITAIELAKGE----PPNS---------D---M-H-PM-RVLF----LIPKNNPPTL------------------VGD-----------FTKSFKEFIDACLNKDPSFRPTAKELLKHKFIVK--NSKKTSYLTELIDRFKRWKA------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11 PsiBlast_PDB 74.2855% -89 - C4 -4FZA MST4_HUMAN B:[6-282] ---------------------------------PEELFTK-------LERIGKGSFGEVFKGIDNRTQQV-VAIKIIDLE---EA--E-DE----IEDIQQEITV-LSQCDSSYVTKYYGSYLKGSKLWIIMEYLGGGS---ALDL---------L---RAGPFDEFQ--IATMLKEILKGLDYL-HS-EKKI-HRDIKAANVLLSE-QG-DVKLAAFGVA------GQLTDTQIKRNTFVGTPFWMAPEVI-----QQ-S--AYDSKADIWSLGITAIELAKGE----PPNS---------D---M-H-PM-RVLF----LIPKNNPPTL------------------VGD-----------FTKSFKEFIDACLNKDPSFRPTAKELLKHKFIVK--NSKKTSYLTELIDRFKRWKA------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32 PsiBlast_CBE 73.7241% -94 - C4 -3Q4Z PAK1_HUMAN A:[7-299] ----------LE--KLRIIVSVGD---------PK------------FEKIGQGASGTVYTAMD----QE-VAIRQMNL-----------KEL--II---NEILV-MRENKNPNIVNYLDSYLVGDELWVVMEYLAGGS---LTDVVT------------ETCMDEGQ--IAAVCRECLQALEFL-HS-NQVI-HRNIKSDNILLGM-DG-SVKLTDFGFC------AQITPEQSKRSTMVGTPYWMAPEVV-----TR-K--AYGPKVDIWSLGIMAIEMIEGE----PPYL---------N---E-N-PL-RALY----LIATNGTPEL------------------QNP-------E--KLSAIFRDFLNRCLEMDVEKRGSAKELIQHQFL-K--IAKPLSSLTPLIAAAKEATKNNHL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14 PsiBlast_PDB 72.8454% -89 - C4 -2XIK STK25_HUMAN A:[17-285] ---------------------------------PEELFTK-------LDRIGKGSFGEVYKGIDNHTKEV-VAIKIIDLE---EA--E--E----IEDIQQEITV-LSQCDSPYITRYFGSYLKSTKLWIIMEYLGGGS---ALDL---------L---KPGPLEETY--IATILREILKGLDYL-HS-ERKI-HRDIKAANVLLSE-QG-DVKLADFGVA------GQLTDTQIKRNTFVGTPFWMAPEVI-----KQ-S--AYDFKADIWSLGITAIELAKGE----PPNS---------D---L-H-PM-RVLF----LIPKNSPPTL------------------EGQ-------H----SKPFKEFVEACLNKDPRFRPTAKELLKHKFITR--YTKKTSFLTELI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16 PsiBlast_PDB 72.5244% -96 - C4 -2J7T STK10_HUMAN A:[17-295] ---------------------------------PNEVWEI-------VGELGDGAFGKVYKAKNKETGAL-AAAKVIE-------EEL-ED----YI---VEIEI-LATCDHPYIVKLLGAYYHDGKLWIMIEFCPGGA---VDAIML-------E---LDRGLTEPQ--IQVVCRQMLEALNFL-HS-KRII-HRDLKAGNVLMTL-EG-DIRLADFGVS------AKNLKTLQK----IGTPYWMAPEVVMCETMKD-T--PYDYKADIWSLGITLIEMAQIE----PPHH---------E---L-N-PM-RVLL----KIAKSDPPTL------------------LTP-------S--KWSVEFRDFLKIALDKNPETRPSAAQLLEHPFV-S--SITSNKALRELVAEA-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19 PsiBlast_PDB 72.2544% -97 - C4 -4BC6 STK10_HUMAN A:[9-287] ---------------------------------PNEVWEI-------VGELGDGAFGKVYKAKNKETGAL-AAAKVIETK---SEEEL-ED----YI---VEIEI-LATCDHPYIVKLLGAYYHDGKLWIMIEFCPGGA---VDAIML-------E---LDRGLTEPQ--IQVVCRQMLEALNFL-HS-KRII-HRDLKAGNVLMTL-EG-DIRLADFGVS------AKNLKTLQ--------PYWMAPEVVMCETMKD-T--PYDYKADIWSLGITLIEMAQIE----PPHH---------E---L-N-PM-RVLL----KIAKSDPPTL------------------LTP-------S--KWSVEFRDFLKIALDKNPETRPSAAQLLEHPFV-S--SITSNKALRELVAEA-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
73 PsiBlast_CBE 71.9735%-107 - C4 -4ARK MP2K1_HUMAN A:[8-304] -------------------------------------FEK-------ISELGAGNGGVVFKVSHKPSGLV-MARKLIHLEIKPAI--R-NQ----II---RELQV-LHECNSPYIVGFYGAFYSDGEISICMEHMDGGS---LDQVLK-----------KAGRIPEQI--LGKVSIAVIKGLTYL-RE-KHKIMHRDVKPSNILVNS-RG-EIKLCDFGVS------GQLIDSMA--NSFVGTRSYMSPERL-----QG-T--HYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMF-----------P-MAIFELLDYIVNEPPPKL------------------PS--------G--VFSLEFQDFVNKCLIKNPAERADLKQLMVHAFI-K--RS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
68 PsiBlast_CBE 71.8035%-104 - C4 -3EQH MP2K1_HUMAN A:[35-331] -------------------------------------FEK-------ISELGAGNGGVVFKVSHKPSGLV-MARKLIHLEIKPAI--R-NQ----II---RELQV-LHECNSPYIVGFYGAFYSDGEISICMEHMDGGS---LDQVLK-----------KAGRIPEQI--LGKVSIAVIKGLTYL-RE-KHKIMHRDVKPSNILVNS-RG-EIKLCDFGVS------GQLIDSMA--NSFVGTRSYMSPERL-----QG-T--HYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMFGC---------P-MAIFELLDYIVNEPPPKL-------------------PS-------G--VFSLEFQDFVNKCLIKNPAERADLKQLMVHAFI-K--RS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
69 PsiBlast_CBE 71.7535%-108 - C4 -3EQG MP2K1_HUMAN A:[35-331] -------------------------------------FEK-------ISELGAGNGGVVFKVSHKPSGLV-MARKLIHLEIKPAI--R-NQ----II---RELQV-LHECNSPYIVGFYGAFYSDGEISICMEHMDGGS---LDQVLK-----------KAGRIPEQI--LGKVSIAVIKGLTYL-RE-KHKIMHRDVKPSNILVNS-RG-EIKLCDFGVS------GQLIDSMA--NSFVGTRSYMSPERL-----QG-T--HYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMFGC---------P-MAIFELLDYIVNEPPPKL-------------------PS-------G--VFSLEFQDFVNKCLIKNPAERADLKQLMVHAFI-K--RS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18 PsiBlast_PDB 71.7444% -98 - C4 -4EQU STK10_HUMAN A:[17-295] ---------------------------------PNEVWEI-------VGELG-----KVYKAKNKETGAL-AAAKVIE---------L-ED----YI---VEIEI-LATCDHPYIVKLLGAYYHDGKLWIMIEFCPGGA---VDAIML-------E---LDRGLTEPQ--IQVVCRQMLEALNFL-HS-KRII-HRDLKAGNVLMTL-EG-DIRLADFGVS------AKNL---------IGTPYWMAPEVVMCETMKD-T--PYDYKADIWSLGITLIEMAQIE----PPHH---------E---L-N-PM-RVLL----KIAKSDPPTL------------------LTP-------S--KWSVEFRDFLKIALDKNPETRPSAAQLLEHPFV-S--SITSNKALRELVAEA-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
80 PsiBlast_CBE 71.7135%-109 - C4 -2P55 MP2K1_HUMAN A:[8-304] -------------------------------------FEK-------ISELGAGNGGVVFKVSHKPSGLV-MARKLIHLEIKPAI--R-NQ----II---RELQV-LHECNSPYIVGFYGAFYSDGEISICMEHMDGGS---LDQVLK-----------KAGRIPEQI--LGKVSIAVIKGLTYL-RE-KHKIMHRDVKPSNILVNS-RG-EIKLCDFGVS------GQLIDSMA-----VGTRSYMSPERL-----QG-T--HYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMF----------PP-MAIFELLDYIVNEPPPKL------------------PS--------G--VFSLEFQDFVNKCLIKNPAERADLKQLMVHAFI-K--RS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
65 PsiBlast_CBE 71.6835%-110 - C4 -3ZLX ? A:[33-329] -------------------------------------FEK-------ISELGAGNGGVVFKVSHKPSGLV-MARKLIHLEIKPAI--R-NQ----II---RELQV-LHECNSPYIVGFYGAFYSDGEISICMEHMDGGS---LDQVLK-----------KAGRIPEQI--LGKVSIAVIKGLTYL-RE-KHKIMHRDVKPSNILVNS-RG-EIKLCDFGVS------GQLIDSMA-----VGTRSYMSPERL-----QG-T--HYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMFGC---------P-MAIFELLDYIVNEPPPKL-------------------PS-------G--VFSLEFQDFVNKCLIKNPAERADLKQLMVHAFI-K--RS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
74 PsiBlast_CBE 71.5435%-115 - C4 -3V04 MP2K1_HUMAN A:[8-304] -------------------------------------FEK-------ISELGAGNGGVVFKVSHKPSGLV-MARKLIHLEIKPAI--R-NQ----II---RELQV-LHECNSPYIVGFYGAFYSDGEISICMEHMDGGS---LDQVLK-----------KAGRIPEQI--LGKVSIAVIKGLTYL-RE-KHKIMHRDVKPSNILVNS-RG-EIKLCDFGVS------GQLIDSMA-----VGTRSYMSPERL-----QG-T--HYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMF----------PP-MAIFELLDYIVNEPPPKL------------------PS--------G--VFSLEFQDFVNKCLIKNPAERADLKQLMVHAFI-K--RS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
78 PsiBlast_CBE 71.3035%-113 - C4 -1S9J MP2K1_HUMAN A:[8-304] -------------------------------------FEK-------ISELGAGNGGVVFKVSHKPSGLV-MARKLIHLEIKPAI--R-NQ----II---RELQV-LHECNSPYIVGFYGAFYSDGEISICMEHMDGGS---LDQVLK-----------KAGRIPEQI--LGKVSIAVIKGLTYL-RE-KHKIMHRDVKPSNILVNS-RG-EIKLCDFGVS------GQLIDSMA-----VGTRSYMSPERL-----QG-T--HYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMF----------PP-MAIFELLDYIVNEPPPKL------------------PS--------G--VFSLEFQDFVNKCLIKNPAERADLKQLMVHAFI-K--RS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26 PsiBlast_CBE 71.1744% -98 - C4 -4EQU STK10_HUMAN B:[17-295] ---------------------------------PNEVWEI-------VGELGDGAFGKVYKAKNKETGAL-AAAKVIE-------EEL-ED----YI---VEIEI-LATCDHPYIVKLLGAYYHDGKLWIMIEFCPGGA---VDAIML-------E---LDRGLTEPQ--IQVVCRQMLEALNFL-HS-KRII-HRDLKAGNVLMTL-EG-DIRLADFGVS------AKNL--------FIGTPYWMAPEVVMCETMKD-T--PYDYKADIWSLGITLIEMAQIE----PPHH---------E---L-N-PM-RVLL----KIAKSDPPTL------------------LTP-------S--KWSVEFRDFLKIALDKNPETRPSAAQLLEHPFV-S--SITSNKALRELVAEA-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
79 PsiBlast_CBE 70.9735%-111 - C4 -3EQB MP2K1_HUMAN A:[8-304] -------------------------------------FEK-------ISELGAGNGGVVFKVSHKPSGLV-MARKLIHLEIKPAI--R-NQ----II---RELQV-LHECNSPYIVGFYGAFYSDGEISICMEHMDGGS---LDQVLK-----------KAGRIPEQI--LGKVSIAVIKGLTYL-RE-KHKIMHRDVKPSNILVNS-RG-EIKLCDFGVS------GQLIDSMA-----VGTRSYMSPERL-----QG-T--HYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMF----------PP-MAIFELLDYIVNEPPPKL------------------PS--------G--VFSLEFQDFVNKCLIKNPAERADLKQLMVHAFI-K--RS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
72 PsiBlast_CBE 70.8635%-107 - C4 -3EQC MP2K1_HUMAN A:[35-331] -------------------------------------FEK-------ISELGAGNGGVVFKVSHKPSGLV-MARKLIHLEIKPAI--R-NQ----II---RELQV-LHECNSPYIVGFYGAFYSDGEISICMEHMDGGS---LDQVLK-----------KAGRIPEQI--LGKVSIAVIKGLTYL-RE-KHKIMHRDVKPSNILVNS-RG-EIKLCDFGVS------GQLIDSMA-----VGTRSYMSPERL-----QG-T--HYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMFGC---------P-MAIFELLDYIVNEPPPKL-------------------PS-------G--VFSLEFQDFVNKCLIKNPAERADLKQLMVHAFI-K--RS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
75 PsiBlast_CBE 70.7535%-114 - C4 -3V01 MP2K1_HUMAN A:[8-304] -------------------------------------FEK-------ISELGAGNGGVVFKVSHKPSGLV-MARKLIHLEIKPAI--R-NQ----II---RELQV-LHECNSPYIVGFYGAFYSDGEISICMEHMDGGS---LDQVLK-----------KAGRIPEQI--LGKVSIAVIKGLTYL-RE-KHKIMHRDVKPSNILVNS-RG-EIKLCDFGVS------GQLIDSMA-----VGTRSYMSPERL-----QG-T--HYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMF----------PP-MAIFELLDYIVNEPPPKL------------------PS--------G--VFSLEFQDFVNKCLIKNPAERADLKQLMVHAFI-K--RS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
66 PsiBlast_CBE 70.5335%-108 - C4 -3ZLS ? A:[33-329] -------------------------------------FEK-------ISELGAGNGGVVFKVSHKPSGLV-MARKLIHLEIKPAI--R-NQ----II---RELQV-LHECNSPYIVGFYGAFYSDGEISICMEHMDGGS---LDQVLK-----------KAGRIPEQI--LGKVSIAVIKGLTYL-RE-KHKIMHRDVKPSNILVNS-RG-EIKLCDFGVS------GQLIDSMA--NSFVGTRSYMSPERL-----QG-T--HYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMFGC---------P-MAIFELLDYIVNEPPPKL-------------------PS-------G--VFSLEFQDFVNKCLIKNPAERADLKQLMVHAFI-K--RS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
63 PsiBlast_CBE 70.5035%-107 - C4 -3ZLY ? A:[33-329] -------------------------------------FEK-------ISELGAG-GGVVFKVSHKPSGLV-MARKLIHLEIKPAI--R-NQ----II---RELQV-LHECNSPYIVGFYGAFYSDGEISICMEHMDGGS---LDQVLK-----------KAGRIPEQI--LGKVSIAVIKGLTYL-RE-KHKIMHRDVKPSNILVNS-RG-EIKLCDFGVS------GQLIDSMA-----VGTRSYMSPERL-----QG-T--HYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMFGC---------P-MAIFELLDYIVNEPPPKL-------------------PS-------G--VFSLEFQDFVNKCLIKNPAERADLKQLMVHAFI-K--RS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28 PsiBlast_CBE 70.4343% -94 - C4 -2UV2 SLK_HUMAN A:[35-312] ---------------------------------PEDFWEI-------IGELGD--FGKVYKAQNKETSVL-AAAKVIDTK---SEEEL-ED----YM---VEIDI-LASCDHPNIVKLLDAFYYENNLWILIEFCAGGA---VDAVML-------E---LERPLTESQ--IQVVCKQTLDALNYL-HD-NKII-HRDLKAGNILFTL-DG-DIKLADFGVS------AKNTRTIQRRDSFIGTPYWMAPEVVMCETSKD-R--PYDYKADVWSLGITLIEMAEIE----PPHH---------E---L-N-PM-RVLL----KIAKSEPPTL------------------AQP-------S--RWSSNFKDFLKKCLEKNVDARWTTSQLLQHPFV-TVDSNKPI---RELIAEA-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
83 PsiBlast_CBE 70.4035%-107 - C4 -3DV3 MP2K1_HUMAN A:[8-304] -------------------------------------FEK-------ISELGAGNGGVVFKVSHKPSGLV-MARKLIHLEIKPAI--R-NQ----II---RELQV-LHECNSPYIVGFYGAFYSDGEISICMEHMDGGS---LDQVLK-----------KAGRIPEQI--LGKVSIAVIKGLTYL-RE-KHKIMHRDVKPSNILVNS-RG-EIKLCDFGVS------GQLIDSMA--N---GTRSYMSPERL-----QG-T--HYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMF-----------P-MAIFELLDYIVNEPPPKL------------------PS--------G--VFSLEFQDFVNKCLIKNPAERADLKQLMVHAFI-K--RS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
76 PsiBlast_CBE 70.3335%-110 - C4 -3E8N MP2K1_HUMAN A:[8-304] -------------------------------------FEK-------ISELGAGNGGVVFKVSHKPSGLV-MARKLIHLEIKPAI--R-NQ----II---RELQV-LHECNSPYIVGFYGAFYSDGEISICMEHMDGGS---LDQVLK-----------KAGRIPEQI--LGKVSIAVIKGLTYL-RE-KHKIMHRDVKPSNILVNS-RG-EIKLCDFGVS------GQLIDSMA--NS-VGTRSYMSPERL-----QG-T--HYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMF----------PP-MAIFELLDYIVNEPPPKL------------------PS--------G--VFSLEFQDFVNKCLIKNPAERADLKQLMVHAFI-K--RS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
70 PsiBlast_CBE 70.2835%-108 - C4 -3EQF MP2K1_HUMAN A:[35-331] -------------------------------------FEK-------ISELGAGNGGVVFKVSHKPSGLV-MARKLIHLEIKPAI--R-NQ----II---RELQV-LHECNSPYIVGFYGAFYSDGEISICMEHMDGGS---LDQVLK-----------KAGRIPEQI--LGKVSIAVIKGLTYL-RE-KHKIMHRDVKPSNILVNS-RG-EIKLCDFGVS------GQLIDSMA--NSFVGTRSYMSPERL-----QG-T--HYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMFGC---------P-MAIFELLDYIVNEPPPKL-------------------PS-------G--VFSLEFQDFVNKCLIKNPAERADLKQLMVHAFI-K--RS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20 PsiBlast_PDB 69.6943% -93 - C4 -2J51 SLK_HUMAN A:[35-312] ---------------------------------PEDFWEI-------IGELGDGAFGKVYKAQNKETSVL-AAAKVIDTK---SEEEL-ED----YM---VEIDI-LASCDHPNIVKLLDAFYYENNLWILIEFCAGGA---VDAVML-------E---LERPLTESQ--IQVVCKQTLDALNYL-HD-NKII-HRDLKAGNILFTL-DG-DIKLADFGVS------AKNTRTIQRRDSFIGTPYWMAPEVVMCETSKD-R--PYDYKADVWSLGITLIEMAEIE----PPHH---------E---L-N-PM-RVLL----KIAKSEPPTL------------------AQP-------S--RWSSNFKDFLKKCLEKNVDARWTTSQLLQHPFV-TVDSNKPI---RELIAEA-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
55 PsiBlast_CBE 69.6839%-108 - C4 -3SLS MP2K1_HUMAN A:[27-285] -------------------------------------FEK-------ISELGAGNGGVVFKVSHKPSGLV-MARKLIHLEIKPAI--R-NQ----II---RELQV-LHECNSPYIVGFYGAFYSDGEISICMEHMDGGS---LDQVLK-----------KAGRIPEQI--LGKVSIAVIKGLTYL-RE-KHKIMHRDVKPSNILVNS-RG-EIKLCDFGVS------GQLI--------FVGTRSYMSPERL-----QG-T--HYSVQSDIWSMGLSLVEMAVGR----YPIG---------------------AIFELLDYIVNEPPPKL-------------------PS-------G--VFSLEFQDFVNKCLIKNPAERADLKQLMVHAFI-K--RS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
82 PsiBlast_CBE 69.4835%-110 - C4 -3MBL MP2K1_HUMAN A:[8-304] -------------------------------------FEK-------ISELGAGNGGVVFKVSHKPSGLV-MARKLIHLEIKPAI--R-NQ----II---RELQV-LHECNSPYIVGFYGAFYSDGEISICMEHMDGGS---LDQVLK-----------KAGRIPEQI--LGKVSIAVIKGLTYL-RE-KHKIMHRDVKPSNILVNS-RG-EIKLCDFGVS------GQLIDSMA--NSFVGTRSYMSPERL-----QG-T--HYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMF-----------P-MAIFELLDYIVNEPPPKL------------------PS--------G--VFSLEFQDFVNKCLIKNPAERADLKQLMVHAFI-K--RS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
77 PsiBlast_CBE 69.3335%-110 - C4 -3DY7 MP2K1_HUMAN A:[8-304] -------------------------------------FEK-------ISELGAGNGGVVFKVSHKPSGLV-MARKLIHLEIKPAI--R-NQ----II---RELQV-LHECNSPYIVGFYGAFYSDGEISICMEHMDGGS---LDQVLK-----------KAGRIPEQI--LGKVSIAVIKGLTYL-RE-KHKIMHRDVKPSNILVNS-RG-EIKLCDFGVS------GQLIDSMA--N---GTRSYMSPERL-----QG-T--HYSVQSDIWSMGLSLVEMAVGRYPIPPP--------------------P-MAIFELLDYIVNEPPPKL------------------PS--------G--VFSLEFQDFVNKCLIKNPAERADLKQLMVHAFI-K--RS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
61 PsiBlast_CBE 69.0539%-105 - C4 -4AN2 MP2K1_HUMAN A:[11-265] -------------------------------------FEK-------ISELGAGNGGVVFKVSHKPSGLV-MARKLIHLEIKPAI--R-NQ----II---RELQV-LHECNSPYIVGFYGAFYSDGEISICMEHMDGGS---LDQVLK-----------KAGRIPEQI--LGKVSIAVIKGLTYL-RE-KHKIMHRDVKPSNILVNS-RG-EIKLCDFGVS------GQLIDEMA--NEFVGTRSYMSPERL-----QG-T--HYSVQSDIWSMGLSLVEMAVGR----YP-----------------R-PP-MAIFELLDYIVNEPPPKL-------------------PS-------A--VFSLEFQDFVNKCLIKNPAERADLKQLMVHAFI-K--RS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
64 PsiBlast_CBE 68.9435%-101 - C4 -3ZM4 ? A:[33-329] -------------------------------------FEK-------ISELGAGNGGVVFKVSHKPSGLV-MARKLIHLEIKPAI--R-NQ----II---RELQV-LHECNSPYIVGFYGAFYSDGEISICMEHMDGGS---LDQVLK-----------KAGRIPEQI--LGKVSIAVIKGLTYL-RE-KHKIMHRDVKPSNILVNS-RG-EIKLCDFGVS------GQLIDSMA------GTRSYMSPERL-----QG-T--HYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMFGC---------P-MAIFELLDYIVNEPPPKL-------------------PS-------G--VFSLEFQDFVNKCLIKNPAERAD-KQLMVHAFI-K--RS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
58 PsiBlast_CBE 68.4339%-104 - C4 -4ANB MP2K1_HUMAN A:[11-265] -------------------------------------FEK-------ISELGAGNGGVVFKVSHKPSGLV-MARKLIHLEIKPAI--R-NQ----II---RELQV-LHECNSPYIVGFYGAFYSDGEISICMEHMDGGS---LDQVLK-----------KAGRIPEQI--LGKVSIAVIKGLTYL-RE-KHKIMHRDVKPSNILVNS-RG-EIKLCDFGVS------GQLIDEMA--NEFVGTRSYMSPERL-----QG-T--HYSVQSDIWSMGLSLVEMAVGR----YP-----------------R-PP-MAIFELLDYIVNEPPPKL-------------------PS-------A--VFSLEFQDFVNKCLIKNPAERADLKQLMVHAFI-K--RS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
57 PsiBlast_CBE 67.9940%-107 - C4 -3ORN MP2K1_HUMAN A:[8-272] -------------------------------------FEK-------ISELGAGNGGVVFKVSHKPSGLV-MARKLIHLEIKPAI--R-NQ----II---RELQV-LHECNSPYIVGFYGAFYSDGEISICMEHMDGGS---LDQVLK-----------KAGRIPEQI--LGKVSIAVIKGLTYL-RE-KHKIMHRDVKPSNILVNS-RG-EIKLCDFGVS------GQLIDSMA--NSFVGTRSYMSPERL-----QG-T--HYSVQSDIWSMGLSLVEMAVGRYPIPP--------------------PP-MAIFELLDYIVNEPPPKL------------------PS--------G--VFSLEFQDFVNKCLIKNPAERADLKQLMVHAFI-K--RS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------