@TOME V2.3
(Nov 2016)

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3D Common Core:

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Modeller Result :

Complexes Modeling
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Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : TBK1_HUMAN: (2013-07-25 )
MQSTSNHLWLLSDILGQGATANVFRGRHKKTGDLFAIKVFNNISFLRPVDVQMREFEVLKKLNHKNIVKLFAIEEETTTRHKVLIMEFCPCGSLYTVLEEPSNAYGLPESEFLIVLRDVVGGMNHLRENGIVHRDIKPGNIMRVIGEDGQSVYKLTDFGAARELEDDEQFVSLYGTEEYLHPDMYERAVLRKDHQKKYGATVDLWSIGVTFYHAATGSLPFRPFEGPRRNKEVMYKIITGKPSGAISGVQKAENGPIDWSGDMPVSCSLSRGLQVLLTPVLANILEADQEKCWGFDQFFAETSDILHRMVIHVFSLQQMTAHKIYIHSYNTATIFHELVYKQTKIISSNQELIYEGRRLVLEPGRLAQHFPKTTEENPIFVVSREPLNTIGLIYEKISLPKVHPRYDLDGDASMAKAITGVVCYACRIASTLLLYQELMRKGIRWLIELIKDDYNETVHKKTEVVITLDFCIRNIEKTVKVYEKLMKINLEAAELGEISDIHTKLLRLSSSQGTIETSLQDIDSRLSPGGSLADAWAHQEGTHPKDRNVEKLQVLLNCMTEIYYQFKKDKAERRLAYNEEQIHKFDKQKLYYHATKAMTHFTDECVKKYEAFLNKSEEWIRKMLHLRKQLLSLTNQCFDIEEEVSKYQEYTNELQETLPQKMFTASSGIKHTMTPIYPSSNTLVEMTLGMKKLKEEMEGVVKELAENNHILERFGSLTMDGGLRNVDCL

Atome Classification :

(41 SA) .....-....10........20......---.---.30..---...---...40----------....-....---50..--......60..-......70.-........80........90........100.......110.......120.......130.......140.......150.......160.-......-170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290...----------....300--.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570.......580.......590.......600.......610.......620.......630.......640.......650.......660.......670.......680.......690.......700.......710.......720.......
(Atome) (Ident) (Tito) (Num) (Ligand) (Uniprot) MQSTS-NHLWLLSDILGQGATANVFRGR---H---KKTGD---LFA---IKVFN----------NISF-LRPV---DVQM--REFEVLKKLN-HKNIVKL-F-AIEEETTTRHKVLIMEFCPCGSLYTVLEEPSNAYGLPESEFLIVLRDVVGGMNHLRENGIVHRDIKPGNIMRVIGEDGQSVYKLTDFGAARE-LEDDEQ-FVSLYGTEEYLHPDMYERAVLRKDHQKKYGATVDLWSIGVTFYHAATGSLPFRPFEGPRRNKEVMYKIITGKPSGAISGVQKAENGPIDWSGDMPVSCSLSRGLQVLLTPVLANILEADQEKCWGF----------DQFFAET--SDILHRMVIHVFSLQQMTAHKIYIHSYNTATIFHELVYKQTKIISSNQELIYEGRRLVLEPGRLAQHFPKTTEENPIFVVSREPLNTIGLIYEKISLPKVHPRYDLDGDASMAKAITGVVCYACRIASTLLLYQELMRKGIRWLIELIKDDYNETVHKKTEVVITLDFCIRNIEKTVKVYEKLMKINLEAAELGEISDIHTKLLRLSSSQGTIETSLQDIDSRLSPGGSLADAWAHQEGTHPKDRNVEKLQVLLNCMTEIYYQFKKDKAERRLAYNEEQIHKFDKQKLYYHATKAMTHFTDECVKKYEAFLNKSEEWIRKMLHLRKQLLSLTNQCFDIEEEVSKYQEYTNELQETLPQKMFTASSGIKHTMTPIYPSSNTLVEMTLGMKKLKEEMEGVVKELAENNHILERFGSLTMDGGLRNVDCL
5 PsiBlast_PDB 96.6699%-106 - C2 -4IW0 TBK1_HUMAN A:[3-658] -QSTS-NHLWLLSDILGQGATANVFRGR---H---KKTGD---LFA---IKVFN----------NISF-LRPV---DVQM--REFEVLKKLN-HKNIVKL-F-AIEEETTTRHKVLIMEFCPCGSLYTVLEEPSNAYGLPESEFLIVLRDVVGGMNHLRENGIVHRNIKPGNIMRVIGEDGQSVYKLTDFGAARE-LEDDEQ-FVSLYGTEEYLHPDMYERAVLRKDHQKKYGATVDLWSIGVTFYHAATGSLPFRPFEGPRRNKEVMYKIITGKPSGAISGVQKAENGPIDWSGDMPVSCSLSRGLQVLLTPVLANILEADQEKCWGF----------DQFFAET--SDILHRMVIHVFSLQQMTAHKIYIHSYNTATIFHELVYKQTKIISSNQELIYEGRRLVLEPGRLAQHFPKTTEENPIFVVSREPLNTIGLIYEKISLPKVHPRYDLDGDASMAKAITGVVCYACRIASTLLLYQELMRKGIRWLIELIKDDYNETVHKKTEVVITLDFCIRNIEKTVKVYEK----------LGEISDIHTKLLRLSSSQGTIETSLQDIDSRLSPGGSLADAWAHQEGTHPKDRNVEKLQVLLNCMTEIYYQFKKDKAERRLAYNEEQIHKFDKQKLYYHATKAMTHFTDECVKKYEAFLNKSEEWIRKMLHLRKQLLSLTNQCFDIEEEVSKYQEYTNELQET------------------------------------------------------------------------
1 PsiBlast_PDB 96.1299%-114 - C2 -4IM3 TBK1_HUMAN A:[7-663] MQSTS-NHLWLLSDILGQGATANVFRGR---H---KKTGD---LFA---IKVFN----------N-----RPV---DVQM--REFEVLKKLN-HKNIVKL-F-AIEEETTTRHKVLIMEFCPCGSLYTVLEEPSNAYGLPESEFLIVLRDVVGGMNHLRENGIVHRNIKPGNIMRVIGEDGQSVYKLTDFG------------------------------------------ATVDLWSIGVTFYHAATGSLPFRPFEGPRRNKEVMYKIITGKPSGAISGVQKAENGPIDWSGDMPVSCSLSRGLQVLLTPVLANILEADQEKCWGF----------DQFFAET--SDILHRMVIHVFSLQQMTAHKIYIHSYNTATIFHELVYKQTKIISSNQELIYEGRRLVLEPGRLAQHFPKTTEENPIFVVSREPLNTIGLIYEKISLPKVHPRYDLDGDASMAKAITGVVCYACRIASTLLLYQELMRKGIRWLIELIKDDYNETVHKKTEVVITLDFCIRNIEKTVKV----------AAELGEISDIHTKLLRLSSSQGTIETSLQDIDSRLSPGGSLADAWAHQEGTHPKDRNVEKLQVLLNCMTEIYYQFKKDKAERRLAYNEEQIHKFDKQKLYYHATKAMTHFTDECVKKYEAFLNKSEEWIRKMLHLRKQLLSLTNQCFDIEEEVSKYQEYTNELQET------------------------------------------------------------------------
4 PsiBlast_PDB 94.8699%-110 - C2 -4IWO TBK1_HUMAN A:[5-660] -QSTS-NHLWLLSDILGQGATANVFRGR---H---KKTGD---LFA---IKVFN----------NISF-LRPV---DVQM--REFEVLKKLN-HKNIVKL-F-AIEEETTTRHKVLIMEFCPCGSLYTVLEEPSNAYGLPESEFLIVLRDVVGGMNHLRENGIVHRDIKPGNIMRVIGEDGQSVYKLTDFGAARE-L-----------GTEEYLHPDMYE------------GATVDLWSIGVTFYHAATGSLPFRPFEGPRRNKEVMYKIITGKPSGAISGVQKAENGPIDWSGDMPVSCSLSRGLQVLLTPVLANILEADQEKCWGF----------DQFFAET--SDILHRMVIHVFSLQQMTAHKIYIHSYNTATIFHELVYKQTKIISSNQELIYEGRRLVLEPGRLAQHFPKTTEENPIFVVSREPLNTIGLIYEKISLPKVHPRYDLDGDASMAKAITGVVCYACRIASTLLLYQELMRKGIRWLIELIKDDYNETVHKKTEVVITLDFCIRNIEKTVKVY---------AAELGEISDIHTKLLRLSSSQGTIETSLQDIDSRLSPGGSLADAWAHQEGTHPKDRNVEKLQVLLNCMTEIYYQFKKDKAERRLAYNEEQIHKFDKQKLYYHATKAMTHFTDECVKKYEAFLNKSEEWIRKMLHLRKQLLSLTNQCFDIEEEVSKYQEYTNELQET------------------------------------------------------------------------
3 PsiBlast_PDB 92.8699%-108 - C2 -4IWQ TBK1_HUMAN A:[4-659] -QSTS-NHLWLLSDILGQGATANVFRGR---H---KKTGD---LFA---IKVFN----------NISF-LRPV---DVQM--REFEVLKKLN-HKNIVKL-F-AIEEETTTRHKVLIMEFCPCGSLYTVLEEPSNAYGLPESEFLIVLRDVVGGMNHLRENGIVHRDIKPGNIMRVIGEDGQSVYKLTDFGAARE-L-----------GTEEYLHPDMYE------------GATVDLWSIGVTFYHAATGSLPFRPFEGPRRNKEVMYKIITGKPSGAISGVQKAENGPIDWSGDMPVSCSLSRGLQVLLTPVLANILEADQEKCWGF----------DQFFAET--SDILHRMVIHVFSLQQMTAHKIYIHSYNTATIFHELVYKQTKIISSNQELIYEGRRLVLEPGRLAQHFPKTTEENPIFVVSREPLNTIGLIYEKISLPKVHPRYDLDGDASMAKAITGVVCYACRIASTLLLYQELMRKGIRWLIELIKDDYNETVHKKTEVVITLDFCIRNIEKTVKVYE-----------LGEISDIHTKLLRLSSSQGTIETSLQDIDSRLSPGGSLADAWAHQEGTHPKDRNVEKLQVLLNCMTEIYYQFKKDKAERRLAYNEEQIHKFDKQKLYYHATKAMTHFTDECVKKYEAFLNKSEEWIRKMLHLRKQLLSLTNQCFDIEEEVSKYQEYTNELQET------------------------------------------------------------------------
2 PsiBlast_PDB 91.9199%-105 - C2 -4IWP TBK1_HUMAN A:[4-659] -QSTS-NHLWLLSDILGQGATANVFRGR---H---KKTGD---LFA---IKVFN----------NISF-LRPV---DVQM--REFEVLKKLN-HKNIVKL-F-AIEEETTTRHKVLIMEFCPCGSLYTVLEEPSNAYGLPESEFLIVLRDVVGGMNHLRENGIVHRDIKPGNIMRVIGEDGQSVYKLTDFGAARE-L-----------GTEEYLHPDMYE------------GATVDLWSIGVTFYHAATGSLPFRPFEGPRRNKEVMYKIITGKPSGAISGVQKAENGPIDWSGDMPVSCSLSRGLQVLLTPVLANILEADQEKCWGF----------DQFFAET--SDILHRMVIHVFSLQQMTAHKIYIHSYNTATIFHELVYKQTKIISSNQELIYEGRRLVLEPGRLAQHFPKTTEENPIFVVSREPLNTIGLIYEKISLPKVHPRYDLDGDASMAKAITGVVCYACRIASTLLLYQELMRKGIRWLIELIKDDYNETVHKKTEVVITLDFCIRNIEKTVKVY---------AAELGEISDIHTKLLRLSSSQGTIETSLQDIDSRLSPGGSLADAWAHQEGTHPKDRNVEKLQVLLNCMTEIYYQFKKDKAERRLAYNEEQIHKFDKQKLYYHATKAMTHFTDECVKKYEAFLNKSEEWIRKMLHLRKQLLSLTNQCFDIEEEVSKYQEYTNELQET------------------------------------------------------------------------
6 PsiBlast_PDB 89.6194%-108 - C2 -4JL9 ? A:[3-657] -QSTS-NHLWLLSDILGQGATANVFRGR---H---KKTGD---LYA---VKVFN----------NISF-LRPV---DVQM--REFEVLKKLN-HKNIVKL-F-AIEEETTTRHKVLIMEFCPCGSLYTVLEEPSNAYGLPESEFLIVLRDVVGGMNHLRENGIVHRDIKPGNIMRVIGEDGQSVYKLTDFGAARE-LEDD--------GTEEYLHPDMYERAVLRKDHQKKYGATVDLWSVGVTFYHAATGSLPFRPFEGPRRNKEVMYKIITGKPSGAISGVQKAENGPIDWSGDMPLSCSLSQGLQALLTPVLANILEADQEKCWGF----------DQFFAET--SDVLHRMVIHVFSLQHMTAHKIYIHSYNTAAVFHELVYKQTKIVSSNQELIYEGRRLVLELGRLAQHFPKTTEENPIFVTSREQLNTVGLRYEKISLPKIHPRYDLDGDASMAKAVTGVVCYACRTASTLLLYQELMRKGVRWLVELVKDDYNETVHKKTEVVITLDFCIRNIEKTVKVYEKLMKVN----ELGEISDIHTKLLRLSSSQGTIESSLQDISSRLSPGGLLADTWAHQEGTHPRDRNVEKLQVLLNCITEIYYQFKKDKAERRLAYNEEQIHKFDKQKLYYHATKAMSHFSEECVRKYEAFKDKSEEWMRKMLHLRKQLLSLTNQCFDIEEEVSKYQDYTNELQE-------------------------------------------------------------------------
7 PsiBlast_PDB 89.2394%-107 - C2 -4JLC ? A:[3-657] -QSTS-NHLWLLSDILGQGATANVFRGR---H---KKTGD---LYA---VKVFN----------NISF-LRPV---DVQM--REFEVLKKLN-HKNIVKL-F-AIEEETTTRHKVLIMEFCPCGSLYTVLEEPSNAYGLPESEFLIVLRDVVGGMNHLRENGIVHRDIKPGNIMRVIGEDGQSVYKLTDFGAARE-LEDD--------GTEEYLHPDMYERAVLRKDHQKKYGATVDLWSVGVTFYHAATGSLPFRPFEGPRRNKEVMYKIITGKPSGAISGVQKAENGPIDWSGDMPLSCSLSQGLQALLTPVLANILEADQEKCWGF----------DQFFAET--SDVLHRMVIHVFSLQHMTAHKIYIHSYNTAAVFHELVYKQTKIVSSNQELIYEGRRLVLELGRLAQHFPKTTEENPIFVTSREQLNTVGLRYEKISLPKIHPRYDLDGDASMAKAVTGVVCYACRTASTLLLYQELMRKGVRWLVELVKDDYNETVHKKTEVVITLDFCIRNIEKTVKVYEKLMKVN----ELGEISDIHTKLLRLSSSQGTIESSLQDISSRLSPGGLLADTWAHQEGTHPRDRNVEKLQVLLNCITEIYYQFKKDKAERRLAYNEEQIHKFDKQKLYYHATKAMSHFSEECVRKYEAFKDKSEEWMRKMLHLRKQLLSLTNQCFDIEEEVSKYQDYTNELQE-------------------------------------------------------------------------
21 PsiBlast_CBE 71.9499%-103 - C2 -4EUT TBK1_HUMAN B:[4-387] -QSTS-NHLWLLSDILGQGATANVFRGR---H---KKTGD---LFA---IKVFN----------NISF-LRPV---DVQM--REFEVLKKLN-HKNIVKL-F-AIEEETTTRHKVLIMEFCPCGSLYTVLEEPSNAYGLPESEFLIVLRDVVGGMNHLRENGIVHRNIKPGNIMRVIGEDGQSVYKLTDFGAARE-LEDDEQ-FVSLYGTEEYLHPDMYERAVLR-------GATVDLWSIGVTFYHAATGSLPFRPFEGPRRNKEVMYKIITGKPSGAISGVQKAENGPIDWSGDMPVSCSLSRGLQVLLTPVLANILEADQEKCWGF----------DQFFAET--SDILHRMVIHVFSLQQMTAHKIYIHSYNTATIFHELVYKQTKIISSNQELIYEGRRLVLEPGRLAQHFPKTTEENPIFVVSRE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8 PsiBlast_PDB 67.7899% -96 - C2 -4EUT TBK1_HUMAN A:[4-387] -QSTS-NHLWLLSDILGQGATANVFRGR---H---KKTGD---LFA---IKVFN----------NISF-LRPV---DVQM--REFEVLKKLN-HKNIVKL-F-AIEEETTTRHKVLIMEFCPCGSLYTVLEEPSNAYGLPESEFLIVLRDVVGGMNHLRENGIVHRNIKPGNIMRVIGEDGQSVYKLTDFGAARE-LEDDEQ-FVSLYGTEEYLHPDMYERAVL--DHQKKYGATVDLWSIGVTFYHAATGSLPFRPFEGPRRNKEVMYKIITGKPSGAISGVQKAENGPIDWSGDMPVSCSLSRGLQVLLTPVLANILEADQEKCWGF----------DQFFAET--SDILHRMVIHVFSLQQMTAHKIYIHSYNTATIFHELVYKQTKIISSNQELIYEGRRLVLEPGRLAQHFPKTTEENPIFVVSRE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
114 HHSearch 62.8899% -88 - C2 -4EUU TBK1_HUMAN A:[4-309] -QSTS-NHLWLLSDILGQGATANVFRGR---H---KKTGD---LFA---IKVFN----------NISF-LRPV---DVQM--REFEVLKKLN-HKNIVKL-F-AIEEETTTRHKVLIMEFCPCGSLYTVLEEPSNAYGLPESEFLIVLRDVVGGMNHLRENGIVHRNIKPGNIMRVIGEDGQSVYKLTDFGAARE-LEDDEQ-FVSLYGTEEYLHPDMYERAVLRKDHQKKYGATVDLWSIGVTFYHAATGSLPFRPFEGPRRNKEVMYKIITGKPSGAISGVQKAENGPIDWSGDMPVSCSLSRGLQVLLTPVLANILEADQEKCWGF----------DQFFAET--SDILH--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
57 PsiBlast_CBE 39.4031% -69 - C2 -1PHK PHKG1_RABIT A:[23-229] -------------EILGRGVSSVVRRCI---H---KPTCK---EYA---VKIIDVTGGGSFSAEEVQE-LR-----EATL--KEVDILRKVSGHPNIIQL-K-DTYE--TNTFFFLVFDLMKKGELFDYLTEKVT---LSEKETRKIMRALLEVICALHKLNIVHRDLKPENILL----DDDMNIKLTDFGFSCQ-LDPGEK-LREVCGTPSYLAPEIIECSM--NDNHPGYGKEVDMWSTGVIMYTLLAGSPPF----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22 PsiBlast_CBE 37.8899% -47 - C2 -4EUU TBK1_HUMAN B:[4-309] -QSTS-NHLWLLSDILGQGATANVFRGR---H---KKTGD---LFA---IKVFN----------NISF-LRPV---DVQM--REFEVLKKLN-HKNIVKL-F-AIEEETTTRHKVLIMEFCPCGSLYTVLEEPSNAYGLPESEFLIVLRDVVGGMNHLRENGIVHRNIKPGNIMRVIGEDGQSVYKLTDFGAARE-LEDDEQ-FV-LYGTEEYLHPDMYERAVLRKDHQKKYGATVDLWSIGVTFYHAATGSLPFRPFEGPRRNKEVMYKIITGKPSGAISGVQKAENGPIDWSGDMPVSCSLSRGLQVLLTPVLANILEADQEKCWGF----------DQFFAET--SDILH--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26 PsiBlast_CBE 37.3533% -75 - C2 -2Z7Q KS6A1_HUMAN A:[24-246] -KADP-SHFELLK-VLGQGSFGKVFLVRKVTR---PDSGH---LYA---MKVL---------------------------------ILADVN-HPFVVKLHY-AFQTEGKL---YLILDFLRGGDLFTRL---SKEVMFTEEDVKFYLAELALGLDHLHSLGIIYRDLKPENIL--LDEEGH--IKLTDFGLSKE-------------GTVEYMAPEVVNR--------QGHSHSADWWSYGVLMFEMLTGSL---PFQGKDR-KETMTLILKAK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24 PsiBlast_CBE 35.7133% -73 - C2 -2Z7S KS6A1_HUMAN A:[24-246] -KADP-SHFELLK-VLGQGSFGKVFLVRKVTR---PDSGH---LYA---MKVLK--------------------------------ILADVN-HPFVVKLHY-AFQTEGKL---YLILDFLRGGDLFTRL---SKEVMFTEEDVKFYLAELALGLDHLHSLGIIYRDLKPENIL--LDEEGH--IKLTDFGLSKE-------------GTVEYMAPEVVNR--------QGHSHSADWWSYGVLMFEMLTGSL---PFQGKDR-KETMTLILKAK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
89 PsiBlast_CBE 34.8331% -66 - C2 -1IG1 DAPK1_HUMAN A:[18-216] ---------------LGSGQFAVVKKCR---E---KSTGL---QYAAKFIKKRR----------TKSS-RRGVSREDIE---REVSILKEIQ-HPNVITL-H-EVYENKT--DVILILELVAGGELFDFLAEKES---LTEEEATEFLKQILNGVYYLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHK-IDFGNE-FKNIFGTPEFVAPEIVNYEPL--------GLEADMWSIGVITYILLSGASPF----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
88 PsiBlast_CBE 33.8131% -65 - C2 -1JKK DAPK1_HUMAN A:[18-216] ---------------LGSGQFAVVKKCR---E---KSTGL---QYAAKFIKKRR----------TKSS-RRGVSREDIE---REVSILKEIQ-HPNVITL-H-EVYENKT--DVILILELVAGGELFDFLAEKES---LTEEEATEFLKQILNGVYYLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHK-IDFGNE-FKNIFGTPEFVAPEIVNYEPL--------GLEADMWSIGVITYILLSGASPF----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
79 PsiBlast_CBE 33.6031% -75 - C2 -3ZXT DAPK1_HUMAN D:[19-217] ---------------LGSGQFAVVKKCR---E---KSTGL---QYAAKFI----------------------VSREDIE---REVSILKEIQ-HPNVITL-H-EVYENKT--DVILILELVAGGELFDFLAE-------TEEEATEFLKQILNGVYYLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHK-ID-----------TPEFVAPEIVNYEPL--------GLEADMWSIGVITYILLSGASPF----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36 PsiBlast_CBE 33.5833% -76 - C2 -2YAA DAPK2_MOUSE B:[20-218] ---------------LGSGQFAIVKKCR---E---KSTGL---EYAAKFIKKRQ----------SRAS-RRGV---CREEIEREVSILRQVL-HPNIITL-H-DVYENRT--DVVLILELVSGGELFDFLAQKES---LSEEEATSFIKQILDGVNYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHE-IEDGVE-FKNIFGTPEFVAPEIVNYEPL--------GLEADMWSIGVITYILLSGASPF----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
75 PsiBlast_CBE 33.4031% -64 - C2 -3DFC DAPK1_HUMAN B:[19-217] ---------------LGSGKFAVVKKCR---E---KSTGL---QYAAKFIKKRR----------TKSS-RRGVSREDIE---REVSILKEIQ-HPNVITL-H-EVYENKT--DVILILELVAGGELFDFLAEKES---LTEEEATEFLKQILNGVYYLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHK-IDFGNE-FKNIFGTPEFVAPEIVNYEPL--------GLEADMWSIGVITYILLSGASPF----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
97 PsiBlast_CBE 33.2831% -75 - C2 -2Y0A DAPK1_HUMAN A:[19-217] ---------------LGSGQFAVVKKCR---E---KSTGL---QYAAKFIKKRR----------TKSS-RRGVSREDIE---REVSILKEIQ-HPNVITL-H-EVYENKT--DVILILELVAGGELFDFLAEKES---LTEEEATEFLKQILNGVYYLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHK-IDFGNE-FKNIFGTPEFVAPEIVNYEPL--------GLEADMWSIGVITYILLSGASPF----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
61 PsiBlast_CBE 33.1332% -78 - C2 -3G51 KS6A3_MOUSE A:[28-242] -----------LLKVLGQGSFGKVFLVK---K---ISGSDARQLYA---MKVLK----------KATL-KVRD-------------ILVEVN-HPFIVKLHY-AFQTEGKL---YLILDFLRGGDLFTRL---SKEVMFTEEDVKFYLAELALALDHLHSLGIIYRDLKPENIL--LDEEGH--IKLTDFGLSKESI------------TVEYMAPEV----VNRRGHTQ----SADWWSFGVLMFEMLTGTL---PFQGKDR-KETMTMILKAK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
94 PsiBlast_CBE 32.5531% -64 - C2 -2W4J DAPK1_HUMAN A:[19-217] ---------------LGSGQFAVVKKCR---E---KSTGL---QYAAKFIKKRR----------TKSS-RRGVSREDIE---REVSILKEIQ-HPNVITL-H-EVYENKT--DVILILELVAGGELFDFLAEKES---LTEEEATEFLKQILNGVYYLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHK-IDFGNE-FKNIFGTPEFVAPEIVNYEPL--------GLEADMWSIGVITYILLSGASPF----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
85 PsiBlast_CBE 32.4931% -63 - C2 -3EHA DAPK1_HUMAN A:[18-216] ---------------LGSGQFAVVKKCR---E---KSTGL---QYAAKFIKKRR----------TKSS-RRGVSREDIE---REVSILKEIQ-HPNVITL-H-EVYENKT--DVILILELVAGGELFDFLAEK-S---LTEEEATEFLKQILNGVYYLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHK-IDFGNE-FKNIFGTPEFVAPEIVNYEPL--------GLEADMWSIGVITYILLSGASPF----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15 PsiBlast_PDB 32.1634% -63 - C2 -2JAM KCC1G_HUMAN A:[6-207] ----NIRKTFIFMEVLGSGAFSEVFLVK---Q---RLTGK---LFA---LKCIK----------KS----------SLE---NEIAVLKKIK-HENIVTL-E-DIYESTT--HYYLVMQLVSGGELFDRILE-RGVYT--EKDASLVIQQVLSAVKYLHENGIVHRDLKPENLLYLTPEENSKI-MITDFGLSK--MEQNGI-MSTACGTPGYVAPEVLA--------QKPYSKAVDCWSIGVITYILLCGYPPF----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
71 PsiBlast_CBE 31.3931% -66 - C2 -3GU7 DAPK1_HUMAN A:[19-217] ---------------LGSGVFAVVKKCR---E---KSTGL---QYAAKFIKKRR----------TKSS-RRGVSREDIE---REVSILKEIQ-HPNVITL-H-EVYENKT--DVILILELVAGGELFDFLAEKES---LTEEEATEFLKQILNGVYYLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHK-IDFGNE-FKNIFGTPEFVAPEIVNYEPL--------GLEADMWSIGVITYILLSGASPF----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
76 PsiBlast_CBE 31.3231% -61 - C2 -3F5U DAPK1_HUMAN A:[19-217] ---------------LGSGQFAVVKKCR---E---KSTGL---QYAAKFIKKRR----------TKSS-RRGVSREDIE---REVSILKEIQ-HPNVITL-H-EVYENKT--DVILILELVAGGELFDFLAEKES---LTEEEATEF-KQILNGVYYLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHK-IDFGNE-FKNIFGTPEFVAPEIVNYEPL--------GLEADMWSIGVITYILLSGASPF----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
95 PsiBlast_CBE 31.2031% -70 - C2 -1WVY DAPK1_HUMAN A:[19-217] ---------------LGSGQFAVVKKCR---E---KSTGL---QYAAKFIKKRR----------TKSS-RRGVSREDIE---REVSILKEIQ-HPNVITL-H-EVYENKT--DVILILELVAGGELFDFLAEKES---LTEEEATEFLKQILNGVYYLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHK-IDFGNE-FKNIFGTPEFVAPEIVNYEPL--------GLEADMWSIGVITYILLSGASPF----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23 PsiBlast_CBE 31.0634% -64 - C2 -2JAM KCC1G_HUMAN B:[4-207] --TTNIRKTFIFMEVLGSGAFSEVFLVK---Q---RLTGK---LFA---LKCIK----------KS----------SLE---NEIAVLKKIK-HENIVTL-E-DIYESTT--HYYLVMQLVSGGELFDRILE-RGVYT--EKDASLVIQQVLSAVKYLHENGIVHRDLKPENLLYLTPEENSKI-MITDFGLSK--MEQNGI-MSTACGTPGYVAPEVLA--------QKPYSKAVDCWSIGVITYILLCGYPPF----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
74 PsiBlast_CBE 31.0531% -62 - C2 -3GU4 DAPK1_HUMAN A:[19-217] ---------------LGSGVFAVVKKCR---E---KSTGL---QYAAKFIKKRR----------TKSS-RRGVSREDIE---REVSILKEIQ-HPNVITL-H-EVYENKT--DVILILELVAGGELFDFLAEKES---LTEEEATEFLKQILNGVYYLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHK-IDFGNE-FKNIFGTPEFVAPEIVNYEPL--------GLEADMWSIGVITYILLSGASPF----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
50 PsiBlast_CBE 31.0032% -74 - C2 -2CKE DAPK2_HUMAN B:[20-218] ---------------LGSGQFAIVKKCR---E---KSTGL---EYAAKFIKKRQ----------SRAS-RRGV---SREEIEREVSILRQVL-HHNVITL-H-DVYENRTD--VVLILELVSGGELFDFLAQKES---LSEEEATSFIKQILDGVNYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHE-IEDGVE-FKNIFGTPEFVAPEIVNYEPL--------GLEADMWSIGVITYILLSGASPF----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
48 PsiBlast_CBE 30.6932% -75 - C2 -2CKE DAPK2_HUMAN D:[20-218] ---------------LGSGQFAIVKKCR---E---KSTGL---EYAAKFIKKRQ----------SRAS-RRGV---SREEIEREVSILRQVL-HHNVITL-H-DVYENRTD--VVLILELVSGGELFDFLAQKES---LSEEEATSFIKQILDGVNYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHE-IEDGVE-FKNIFGTPEFVAPEIVNYEPL--------GLEADMWSIGVITYILLSGASPF----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25 PsiBlast_CBE 30.3133% -71 - C2 -2Z7R KS6A1_HUMAN A:[24-246] -KADP-SHFELLK-VLGQGSFGKVFLVRKVTR---PDSGH---LYA---MKVLK----------KATL-KV---------------ILADVN-HPFVVKLHY-AFQTEGKL---YLILDFLRGGDLFTRL---SKEVMFTEEDVKFYLAELALGLDHLHSLGIIYRDLKPENIL--LDEEGH--IKLTDFGLSKE-------------GTVEYMAPEVVNR--------QGHSHSADWWSYGVLMFEMLTGSL---PFQGKDR-KETMTLILKAK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
80 PsiBlast_CBE 30.2131% -69 - C2 -3ZXT DAPK1_HUMAN B:[19-217] ---------------LGSGQFAVVKKCR---E---KSTGL---QYAAKFIKKRR----------TKS--RRGVSREDIE---REVSILKEIQ-HPNVITL-H-EVYENKT--DVILILELVAGGELFDFLAEK-----LTEEEATEFLKQILNGVYYLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHK-ID-----------TPEFVAPEIVNYEPL--------GLEADMWSIGVITYIL-SGASPF----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
73 PsiBlast_CBE 30.1431% -66 - C2 -3GU5 DAPK1_HUMAN A:[19-217] ---------------LGSGVFAVVKKCR---E---KSTGL---QYAAKFIKKRR----------TKSS-RRGVSREDIE---REVSILKEIQ-HPNVITL-H-EVYENKT--DVILILELVAGGELFDFLAEKES---LTEEEATEFLKQILNGVYYLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHK-IDFGNE-FKNIFGTPEFVAPEIVNYEPL--------GLEADMWSIGVITYILLSGASPF----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30 PsiBlast_CBE 30.0435% -56 - C2 -2WEL KCC2D_HUMAN A:[12-206] ---------------LGKGAFSVVRRCM---K---IPTGQ---EYA---AKIIN----------TKK--LSAR---DHQKLEREARICRLLK-HPNIVRL-HDSISEEG---FHYLVFDLVTGGELF---EDIVAREYYSEADASHCIQQILESVNHCHLNGIVHRDLKPENLLLASKSKGAAV-KLADFGLAIE-VQGDQQAWFGFAGTPGYLSPE-----VLRKD---PYGKPVDMWACGVILYILLVGYPPF----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
72 PsiBlast_CBE 29.6531% -65 - C2 -3GU6 DAPK1_HUMAN A:[19-217] ---------------LGSGVFAVVKKCR---E---KSTGL---QYAAKFIKKRR----------TKSS-RRGVSREDIE---REVSILKEIQ-HPNVITL-H-EVYENKT--DVILILELVAGGELFDFLAEKES---LTEEEATEFLKQILNGVYYLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHK-IDFGNE-FKNIFGTPEFVAPEIVNYEPL--------GLEADMWSIGVITYILLSGASPF----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
122 HHSearch 29.4733% -72 - C2 -3UBD KS6A3_MOUSE A:[26-297] ---------FELLKVLGQGSFGKVFLVK---KISGSDARQ---LYA---MKVLK----------KATLKVRDR---V--------DILVEVN-HPFIVKL-H-YAFQT--EGKLYLILDFLRGGDLFTRLSK---EVMFTEEDVKFYLAELALALDHLHSLGIIYRDLKPENIL--LDEEGH--IKLTDFGLSKE-----KK-AYSFCGTVEYMAPEVVN--------RRGHTQSADWWSFGVLMFEMLTGTLPFQ---G-KDRKETMTMILKAK---------------L----GMPQ--FLSPEAQ----SLLRMLFKRNPANRLGAGPDGVEEIKRHSFFSTIDWNKLYRRE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
37 PsiBlast_CBE 29.1233% -74 - C2 -2YAA DAPK2_MOUSE A:[20-218] ---------------LGSGQFAIVKKCR---E---KSTGL---EYAAKFIKKRQ----------SRAS-RRGV---CREEIEREVSILRQVL-HPNIITL-H-DVYENRT--DVVLILELVSGGELFDFLAQKES---LSEEEATSFIKQILDGVNYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHE-IEDGVE-FKNIFGTPEFVAPEIVNYEPL--------GLEADMWSIGVITYILLSGASPF----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
83 PsiBlast_CBE 28.6231% -63 - C2 -1P4F DAPK1_HUMAN A:[18-216] ---------------LGSGQFAVVKKCR---E---KSTGL---QYAAKFIKKRR----------TKSS-RRGVSREDIE---REVSILKEIQ-HPNVITL-H-EVYENKT--DVILILELVAGGELFDF----------TEEEATEFLKQILNGVYYLHSLQIAHFDLKPENIMLLDRNVP--RIKIIDFGLAHK-IDFGNE-FKNIFGTPEFVAPEIVNYEPL--------GLEADMWSIGVITYILLSGASPF----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
58 PsiBlast_CBE 24.6632% -61 - C2 -4GUE KS6A3_MOUSE A:[29-243] -----------LLKVLGQGSFGKVFLVK---K---ISGSDARQLYA---MKVLK----------KATL-KVRD---RV---------LVEVN-HPFIVKLHY-AFQTEGKL---YLILDFLRGGDLFTRL---SKEVMFTEEDVKFYLAELALALDHLHSLGIIYRDLKPENIL--LDEEGH--IKLTDFGLSKE-----KK-AYSFCGTVEYMAPEV----VNRRGHTQ----SADWWSFGVLMFEMLTGTL---PFQGKDR-KETMTMILKAK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
59 PsiBlast_CBE 24.0732% -59 - C2 -4EL9 KS6A3_MOUSE A:[29-243] -----------LLKVLGQGSFGKVFLVK---K---ISGSDARQLYA---MKVLK----------KATL-KVRD---RVR------DILVEVN-HPFIVKLHY-AFQTEGKL---YLILDFLRGGDLFTRL---SKEVMFTEEDVKFYLAELALALDHLHSLGIIYRDLKPENIL--LDEEGH--IKLTDFGLSKES---EKK-AYSFCGTVEYMAPEV----VNRRGHTQ----SADWWSFGVLMFEMLTGTL---PFQGKDR-KETMTMILKAK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------