@TOME V2.3
(Nov 2016)

Ref. - - Doc.
Global output mode :
Sort entries by :
Sequence Color type :

Show alignment :
Column output:
Score:

Alignment:

3D Common Core:

Structural Clustering:

Modeller Result :

Complexes Modeling
Templates Information:
Sequence & Result Tab:

Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : AAPK1_HUMAN: (2015-10-02 )
MRRLSSWRKMATAEKQKHDGRVKIGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISLLKHMLQVDPMKRATIKDIREHEWFKQDLPKYLFPEDPSYSSTMIDDEALKEVCEKFECSEEEVLSCLYNRNHQDPLAVAYHLIIDNRRIMNEAKDFYLATSPPDSFLDDHHLTRPHPERVPFLVAETPRARHTLDELNPQKSKHQGVRKAKWHLGIRSQSRPNDIMAEVCRAIKQLDYEWKVVNPYYLRVRRKNPVTSTYSKMSLQLYQVDSRTYLLDFRSIDDEITEAKSGTATPQRSGSVSNYRSCQRSDSDAEAQGKSSEVSLTSSVTSLDSSPVDLTPRPGSHTIEFFEMCANLIKILAQ

Atome Classification :

(83 SA) .........10........20........30........40........50........----60......---..70-........-80.-.-.......90....--.----...100.......110.......----120--.-........130.......140.-......150.....---.-----.160-.---.----.---..--....170..----.-...---.-180.......190.......200-----.--......210.......220.......230--..-...-..--..240.--.-...----.----.---..250-...--.....260.....-----.-----.270----.-........280--------------.......290--.......--300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......
(Atome) (Ident) (Tito) (Num) (Ligand) (Uniprot) MRRLSSWRKMATAEKQKHDGRVKIGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILN----RQKIRSLD---VVGK-IRREIQNL-K-L-F-RHPHIIKLYQVIS--T----PSDIFMVMEYVSGGELFDYICKN----G----R-LDEKESRRLFQQILSGVDYCHR-HMVVHRDLKPENVL---L-----DA---H---M----N---AK--IADFGLSNM----M-SDG---E-FLRTSCGSPNYAAPEVISGRLYA-----G--PEVDIWSSGVILYALLCGTLPFDDDHV----PT-LFK-KI--CDG--I--F-YTP----Q----Y---LNPS--VIS--LLKHMLQVDPMKR-----A-----TI------K-DIREHEWFKQD--------------LPKYLFPEDP--SYSSTMI--DDEALKEVCEKFECSEEEVLSCLYNRNHQDPLAVAYHLIIDNRRIMNEAKDFYLATSPPDSFLDDHHLTRPHPERVPFLVAETPRARHTLDELNPQKSKHQGVRKAKWHLGIRSQSRPNDIMAEVCRAIKQLDYEWKVVNPYYLRVRRKNPVTSTYSKMSLQLYQVDSRTYLLDFRSIDDEITEAKSGTATPQRSGSVSNYRSCQRSDSDAEAQGKSSEVSLTSSVTSLDSSPVDLTPRPGSHTIEFFEMCANLIKILAQ
2 PsiBlast_PDB 91.7798%-122 - C4 -4RER AAPK1_HUMAN A:[1-540] -------------------GSVKIGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILN----RQKIRSLD---VVGK-IRREIQNL-K-L-F-RHPHIIKLYQVIS--T----PSDIFMVMEYVSGGELFDYICKN----G----R-LDEKESRRLFQQILSGVDYCHR-HMVVHRDLKPENVL---L-----DA---H---M----N---AK--IADFGLSNM----M-SDG---E-FLRTSCGSPNYAAPEVISGRLYA-----G--PEVDIWSSGVILYALLCGTLPFDDDHV----PT-LFK-KI--CDG--I--F-YTP----Q----Y---LNPS--VIS--LLKHMLQVDPMKR-----A-----SI------K-DIREHEWFKQD--------------LPKYLFPEDP--SYS------DDEALKEVCEKFECSEEEVLSCLYNRNHQDPLAVAYHLIIDNRRIMNEAKDFYLATSPPD----DHHLTRPHPERVPFLVAETP-------------------RKAKWHLGIRSQSRPNDIMAEVCRAIKQLDYEWKVVNPYYLRVRRKNPVTSTYSKMSLQLYQVDSRTYLLDFRSIDDGIT------------------------------------------------------PRPGSHTIEFFEMCANLIKILAQ
4 PsiBlast_PDB 88.3489%-124 - C4 -4QFR ? A:[11-503] -------------------GRVKIGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILN----RQKIRSLD---VVGK-IRREIQNL-K-L-F-RHPHIIKLYQVIS--T----PSDIFMVMEYVSGGELFDYICKN----G----R-LDEKESRRLFQQILSGVDYCHR-HMVVHRDLKPENVL---L-----DA---H---M----N---AK--IADFGLSNM----M-SDG---E-FLRTSCGSPNYAAPEVISGRLYA-----G--PEVDIWSSGVILYALLCGTLPFDDDHV----PT-LFK-KI--CDG--I--F-YTP----Q----Y---LNPS--VIS--LLKHMLQVDPMKR-----A-----TI------K-DIREHEWFKQD--------------LPKYLF-------------------------------------------------------------------------------------------------------------------------KWHLGIRSQSRPNDIMAEVCRAIKQLDYEWKVVNPYYLRVRRKNPVTSTFSKMSLQLYQVDSRTYLLDFRSIDD----------------S---------------------------------------------HTIEFFEMCANLIKILAQ
3 PsiBlast_PDB 87.3689%-121 - C4 -4QFG AAPK1_RAT A:[11-503] -------------------GRVKIGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILN----RQKIRSLD---VVGK-IRREIQNL-K-L-F-RHPHIIKLYQVIS--T----PSDIFMVMEYVSGGELFDYICKN----G----R-LDEKESRRLFQQILSGVDYCHR-HMVVHRDLKPENVL---L-----DA---H---M----N---AK--IADFGLSNM----M-SDG---E-FLRTSCGSPNYAAPEVISGRLYA-----G--PEVDIWSSGVILYALLCGTLPFDDDHV----PT-LFK-KI--CDG--I--F-YTP----Q----Y---LNPS--VIS--LLKHMLQVDPMKR-----A-----TI------K-DIREHEWFKQD--------------LPKYLFP-------------------------------------------------------------------------------------------------------------------------WHLGIRSQSRPNDIMAEVCRAIKQLDYEWKVVNPYYLRVRRKNPVTSTFSKMSLQLYQVDSRTYLLDFRSIDDE------------RPGS---------------------------------------------HTIEFFEMCANLIKILAQ
5 PsiBlast_PDB 86.9989%-123 - C4 -4QFS AAPK1_RAT A:[11-503] -------------------GRVKIGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILN----RQKIRSLD---VVGK-IRREIQNL-K-L-F-RHPHIIKLYQVIS--T----PSDIFMVMEYVSGGELFDYICKN----G----R-LDEKESRRLFQQILSGVDYCHR-HMVVHRDLKPENVL---L-----DA---H---M----N---AK--IADFGLSNM----M-SDG---E-FLRTSCGSPNYAAPEVISGRLYA-----G--PEVDIWSSGVILYALLCGTLPFDDDHV----PT-LFK-KI--CDG--I--F-YTP----Q----Y---LNPS--VIS--LLKHMLQVDPMKR-----A-----TI------K-DIREHEWFKQD--------------LPKYLF-------------------------------------------------------------------------------------------------------------------------KWHLGIRSQSRPNDIMAEVCRAIKQLDYEWKVVNPYYLRVRRKNPVTSTFSKMSLQLYQVDSRTYLLDFRSIDD----------------S---------------------------------------------HTIEFFEMCANLIKILAQ
1 PsiBlast_PDB 86.0199%-109 - C4 -4REW AAPK1_HUMAN A:[1-540] -------------------GSVKIGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILN----RQKIRSLD---VVGK-IRREIQNL-K-L-F-RHPHIIKLYQVIS--T----PSDIFMVMEYVSGGELFDYICKN----G----R-LDEKESRRLFQQILSGVDYCHR-HMVVHRDLKPENVL---L-----DA---H---M----N---AK--IADFGLSNM----M-SDG---E-FLRTSCGSPNYAAPEVISGRLYA-----G--PEVDIWSSGVILYALLCGTLPFDDDHV----PT-LFK-KI--CDG--I--F-YTP----Q----Y---LNPS--VIS--LLKHMLQVDPMKR-----A-----SI------K-DIREHEWFKQD--------------LPKYLFPE----------------------------------------------------IDNRRIMNEAKDFYLATSPPD-----HHLTRPHPERVPFLVAET--------------------RKAKWHLGIRSQSRPNDIMAEVCRAIKQLDYEWKVVNPYYLRVRRKNPVTSTYSKMSLQLYQVDSRTYLLDFRSIDDG--------------------------------------------------------PRPGSHTIEFFEMCANLIKILAQ
6 PsiBlast_PDB 81.9198%-121 - C4 -4CFH AAPK1_RAT A:[29-489] --------------------RVKIGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILN----RQKIRSLD---VVGK-IRREIQNL-K-L-F-RHPHIIKLYQVIS--T----PSDIFMVMEYVSGGELFDYICKN----G----R-LDEKESRRLFQQILSGVDYCHR-HMVVHRDLKPENVL---L-----DA---H---M----N---AK--IADFGLSNM----M-SDG---E-FLRTSCGSPNYAAPEVISGRLYA-----G--PEVDIWSSGVILYALLCGTLPFDDDHV----PT-LFK-KI--CDG--I--F-YTP----Q----Y---LNPS--VIS--LLKHMLQVDPMKR-----A-----TI------K-DIREHEWFKQD--------------LPKYLFPED--------------------------------------------AVAYHLIIDNRRIMNEAKDFYLATSPPDSFLDDHHLTRPHPERVPFLVAETPRA-------------------AKWHLGIRSQSRPNDIMAEVCRAIKQLDYEWKVVNPYYLRVRRKNPVTSTFSKMSLQLYQVDSRTYLLDFRSIDDEI------------------------------------------------------------------------------
12 PsiBlast_PDB 69.6390%-115 - C4 -3AQV AAPK2_HUMAN A:[4-276] -----------------HDGRVKIGHYVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILN----RQKIRSLD---VVGK-IKREIQNL-K-L-F-RHPHIIKLYQVIS--T----PTDFFMVMEYVSGGELFDYICKH----G----R-VEEMEARRLFQQILSAVDYCHR-HMVVHRDLKPENVL---L-----DA---H---M----N---AK--IADFGLSNM----M-SDG---E-FL------PNYAAPEVISGRLYA-----G--PEVDIWSCGVILYALLCGTLPFDDEHV----PT-LFK-KI--RGG--V--F-YIP----E----Y---LNRS--VAT--LLMHMLQVDPLKR-----A-----TI------K-DIREHEWFKQD--------------LPSYLFPE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
124 HHSearch 58.9943% -99 - C4 -4BKY MELK_HUMAN A:[9-326] -----------------------LKYYELHETIGTGGFAKVKLACHILTGEMVAIKIMD----KNTL-------DLPR-IKTEIEAL-K-N-L-RHQHICQLYHVLE--T----ANKIFMVLEYCPGGELFDYIISQ----D----R-LSEEETRVVFRQIVSAVAYVHS-QGYAHRDLKPENLL---F-----DE---Y---H----K---LK--LIDFGLCA----------------------SLAYAAPELIQGK--------G--SEADVWSMGILLYVLMCGFLPFDDDNV----MA-LYK-KI--MRG--K--Y-DVP----K----W---LSPS--SIL--LLQQMLQVDPKKR-----I-----SM------K-NLLNHPWIMQD--------------YNY---PVEWQSKNPFIHL--DDDCVTELSVHHRNNRQTMEDLI-SLWQYDHLTATYLLLLAKKARGKPVRLR----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36 PsiBlast_CBE 55.5348%-104 - C4 -4CQG MELK_MOUSE A:[8-266] -----------------------LKYYELYETIGTGGFAKVKLACHVLTGEMVAIKIMD----KNALGS-----DLPR-VKTEIDAL-K-S-L-RHQHICQLYHVLE--T----KNKIFMVLEYCPGGELFDYIISQ----D----R-LSEEETRVVFRQILSAVAYVHS-QGYAHRDLKPENLL---F-----DE---N---H----K---LK--LIDFGLCAK-------------------CGSLAYAAPELIQG------------SEADVWSMGILLYVLMCGFLPFDDDNV----MA-LYK-KI--MRG--K--Y-EVP----K----W---LSPS--SIL--LLQQMLQVDPKKR-----I-----SM------R-NLLNHPWVMQD--------------YSCPVEWQSK--TPLTHLD--EDCVTELSVHHRSSRQTMEDLISSWQYDHLTATYLLLLAKKARLEHHH--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26 PsiBlast_CBE 55.2845% -97 - C4 -4CZU CIPKN_ARATH D:[4-277] -----------------HSGRTRVGKYELGRTLGEGTFAKVKFARNVENGDNVAIKVID----KEKVLKNK---MIAQ-IKREISTM-K-L-I-KHPNVIRMFEVMA--S----KTKIYFVLEFVTGGELFDKISSN----G----R-LKEDEARKYFQQLINAVDYCHS-RGVYHRDLKPENLL---L-----DA---N---G----A---LK--VSDFGLSALPQQVR-EDG-----LLHDTCGTPNYVAPEVINNKGYD-----G--AKADLWSCGVILFVLMAGYLPFEDSNL----TS-LYK-KI--FKA--E--F-TCP----P----W---FSAS--AKK--LIKRILDPNPATR-----I-----TF------A-EVIENEWFKKGYK------------APKFENADVS--LDDVDAI--FDDSNLVVERRE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17 PsiBlast_PDB 55.0645%-100 - C4 -4CZU CIPKN_ARATH A:[4-277] -----------------HSGRTRVGKYELGRTLGEGTFAKVKFARNVENGDNVAIKVID----KEKVLKNK---MIAQ-IKREISTM-K-L-I-KHPNVIRMFEVMA--S----KTKIYFVLEFVTGGELFDKISSN----G----R-LKEDEARKYFQQLINAVDYCHS-RGVYHRDLKPENLL---L-----DA---N---G----A---LK--VSDFGLSALPQQVR-EDG-----LLHDTCGTPNYVAPEVINNKGYD-----G--AKADLWSCGVILFVLMAGYLPFEDSNL----TS-LYK-KI--FKA--E--F-TCP----P----W---FSAS--AKK--LIKRILDPNPATR-----I-----TF------A-EVIENEWFKKGYK------------APKFENDDVD--AIFDDSG--ESKNLVV-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23 PsiBlast_CBE 54.4445% -94 - C4 -4CZT CIPKN_ARATH D:[4-277] -----------------HSGRTRVGKYELGRTLGEGTFAKVKFARNVENGDNVAIKVID----KEKVLKNK---MIAQ-IKREISTM-K-L-I-KHPNVIRMFEVMA--S----KTKIYFVLEFVTGGELFDKISSN----G----R-LKEDEARKYFQQLINAVDYCHS-RGVYHRDLKPENLL---L-----DA---N---G----A---LK--VSDFGLSALPQQVR-EDG-----LLHTTCGTPNYVAPEVINNKGYD-----G--AKADLWSCGVILFVLMAGYLPFEDSNL----TS-LYK-KI--FKA--E--F-TCP----P----W---FSAS--AKK--LIKRILDPNPATR-----I-----TF------A-EVIENEWFKKGYK------------APKFENADVS--LDDVDAI--FDDSNLVVERRE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
127 HHSearch 53.9338%-108 - C4 -4GV1 AKT1_HUMAN A:[3-270] -------------------SRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILK----KEVIVAKD---EVAH-TLTENRVL-Q-N-S-RHPFLTALKYSFQ--T----HDRLCFVMEYANGGELFFHLSRE----R----V-FSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLM---L-----DK---D---G----H---IK--ITDFGLCKEG---I-KDG---A-TMKTFCGTPEYLAPEVLEDNDY------G--RAVDWWGLGVVMYEMMCGRLPFYNQDH----EK-LFE-LI--LME--E--I-RFP----R----T---LGPE--AKS--LLSGLLKKDPKQR-----LGGGSEDA------K-EIMQHRFFAGI--------------VWQHVYEKKL--SPPFKPQ--VTSETDTRYFDEEFTAQMITITPSMECVDSERRPHFPQFDYSAS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27 PsiBlast_CBE 53.6045%-100 - C4 -4CZU CIPKN_ARATH C:[9-277] ----------------------RVGKYELGRTLGEGTFAKVKFARNVENGDNVAIKVID----KEKVLKNK---MIAQ-IKREISTM-K-L-I-KHPNVIRMFEVMA--S----KTKIYFVLEFVTGGELFDKISSN----G----R-LKEDEARKYFQQLINAVDYCHS-RGVYHRDLKPENLL---L-----DA---N---G----A---LK--VSDFGLSALPQQVR-EDG-----LLHDTCGTPNYVAPEVINNKGYD-----G--AKADLWSCGVILFVLMAGYLPFEDSNL----TS-LYK-KI--FKA--E--F-TCP----P----W---FSAS--AKK--LIKRILDPNPATR-----I-----TF------A-EVIENEWFKKGYK------------APKFENADVD--AIFDDS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24 PsiBlast_CBE 53.5845%-101 - C4 -4CZT CIPKN_ARATH C:[10-277] -----------------------VGKYELGRTLGEGTFAKVKFARNVENGDNVAIKVID----KEKVLKNK---MIAQ-IKREISTM-K-L-I-KHPNVIRMFEVMA--S----KTKIYFVLEFVTGGELFDKISSN----G----R-LKEDEARKYFQQLINAVDYCHS-RGVYHRDLKPENLL---L-----DA---N---G----A---LK--VSDFGLSALPQQVR-EDG-----LLHTTCGTPNYVAPEVINNKGYD-----G--AKADLWSCGVILFVLMAGYLPFEDSNL----TS-LYK-KI--FKA--E--F-TCP----P----W---FSAS--AKK--LIKRILDPNPATR-----I-----TF------A-EVIENEWFKKGYK------------APKFENADVS--LDDVDAI--FDDSG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28 PsiBlast_CBE 53.2845% -96 - C4 -4CZU CIPKN_ARATH B:[4-277] -----------------HSGRTRVGKYELGRTLGEGTFAKVKFARNVENGDNVAIKVID----KEKVLKNK---MIAQ-IKREISTM-K-L-I-KHPNVIRMFEVMA--S----KTKIYFVLEFVTGGELFDKISSN----G----R-LKEDEARKYFQQLINAVDYCHS-RGVYHRDLKPENLL---L-----DA---N---G----A---LK--VSDFGLSALPQQVR-EDG-----LLHDTCGTPNYVAPEVINNKGYD-----G--AKADLWSCGVILFVLMAGYLPFEDSNL----TS-LYK-KI--FKA--E--F-TCP----P----W---FSAS--AKK--LIKRILDPNPATR-----I-----TF------A-EVIENEWFKKGYK------------APKFEDDVDA--IFDDSG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
96 PsiBlast_CBE 53.1937%-102 - C4 -3IGO ? A:[30-282] --------------------------------LGKGSFGEVLKCKDRITQQEYAVKVIN----KASAKNK----T-ST-ILREVELL-K-K-L-DHPNIMKLFEILE--D----SSSFYIVGELYTGGELFDEIIKR----K----R-FSEHDAARIIKQVFSGITYMHK-HNIVHRDLKPENIL---L-----ES---KEKDC----D---IK--IIDFGLSTC----F-QQN---T--------TAYYIAPEVLRGTY-------D--EKCDVWSAGVILYILLSGTPPFYGKNE----YD-ILK-RV--ETGKYA--F-DLP----Q----WRT-ISDD--AKD--LIRKMLTFHPSLR-----I-----TA------T-QCLEHPWIQKY--------------SSETPTISDL--PSLESAM--TNIRQFQAEKKLAQAALLYMASKLTTLDETKQLTEIFRKLDTNNDGMLDRDELVRGYHEFMRLKGVDSNSLIQGSTIEDQIDSLMPLLDMDGSGSIEYSEFIASAIDRTILLSRERMERAFKMFDKDGSGKISTKELFKLESIIEQVDNNKDGEVDFNEFVEMLQNFVRN------------------------------------------------------------------------------------------
16 PsiBlast_PDB 52.6345% -96 - C4 -4CZT CIPKN_ARATH A:[4-277] -----------------HSGRTRVGKYELGRTLGEGTFAKVKFARNVENGDNVAIKVID----KEKVLKNK---MIAQ-IKREISTM-K-L-I-KHPNVIRMFEVMA--S----KTKIYFVLEFVTGGELFDKISSN----G----R-LKEDEARKYFQQLINAVDYCHS-RGVYHRDLKPENLL---L-----DA---N---G----A---LK--VSDFGLSALPQQVR-EDG-----LLHTTCGTPNYVAPEVINNKGYD-----G--AKADLWSCGVILFVLMAGYLPFEDSNL----TS-LYK-KI--FKA--E--F-TCP----P----W---FSAS--AKK--LIKRILDPNPATR-----I-----TF------A-EVIENEWFKKGYK------------APKFENVSLD--DVDAIFD--DSGES---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25 PsiBlast_CBE 52.3045% -97 - C4 -4CZT CIPKN_ARATH B:[4-277] -----------------HSGRTRVGKYELGRTLGEGTFAKVKFARNVENGDNVAIKVID----KEKVLKNK---MIAQ-IKREISTM-K-L-I-KHPNVIRMFEVMA--S----KTKIYFVLEFVTGGELFDKISSN----G----R-LKEDEARKYFQQLINAVDYCHS-RGVYHRDLKPENLL---L-----DA---N---G----A---LK--VSDFGLSALPQQVR-EDG-----LLHTTCGTPNYVAPEVINNKGYD-----G--AKADLWSCGVILFVLMAGYLPFEDSNL----TS-LYK-KI--FKA--E--F-TCP----P----W---FSAS--AKK--LIKRILDPNPATR-----I-----TF------A-EVIENEWFKKGYK------------APKFEDDVDA--IFDDSG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
93 PsiBlast_CBE 52.1937% -97 - C4 -4Y5Q ? A:[30-282] --------------------------------LGKGSFGEVLKCKDRITQQEYAVKVIN----KASAKNKD---T-ST-ILREVELL-K-K-L-DHPNIMKLFEILE--D----SSSFYIVGELYTGGELFDEIIKR----K----R-FSEHDAARIIKQVFSGITYMHK-HNIVHRDLKPENIL---L-----ES---KEKDC----D---IK--IIDFGLSTC----F-QQN---T----DRIGTAYYIAPEVLRGTY-------D--EKCDVWSAGVILYILLSGTPPFYGKNE----YD-ILK-RV--ETGKYA--F-DLP----Q----WRT-ISDD--AKD--LIRKMLTFHPSLR-----I-----TA------T-QCLEHPWIQKY--------------SSETPTISDL--PSLESAM--TNIRQFQAEKKLAQAALLYMASKLTTLDETKQLTEIFRKLDTNNDGMLDRDELVRGYHEFMRLKGVDSNSGSTIEDQIDSLMPLLDMDGSGSIEYSEFIASAIDRTILLSRERMERAFKMFDKDGSGKISTKELFKLFSEQVDNNKDGEVDFNEFVEMLQNFVRN-----------------------------------------------------------------------------------------------
35 PsiBlast_CBE 52.1746% -94 - C4 -4BKY MELK_HUMAN A:[9-291] -----------------------LKYYELHETIGTGGFAKVKLACHILTGEMVAIKIMD----KNTL-------DLPR-IKTEIEAL-K-N-L-RHQHICQLYHVLE--T----ANKIFMVLEYCPGGELFDYIISQ----D----R-LSEEETRVVFRQIVSAVAYVHS-QGYAHRDLKPENLL---F-----DE---Y---H----K---LK--LIDFGLCA----------------------SLAYAAPELIQGK--------G--SEADVWSMGILLYVLMCGFLPFDDDNV----MA-LYK-KI--MRG--K--Y-DVP----K----W---LSPS--SIL--LLQQMLQVDPKKR-----I-----SM------K-NLLNHPWIMQD-----------------YNYPVEW--QSKNPFIHLDDDCVTELSVHHRNNRQTMEDLISLWQYDHLTATYLLLLAKKARGKPVRLR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
86 PsiBlast_CBE 52.0237%-111 - C4 -4FG8 KCC1A_HUMAN A:[20-279] --------------------------YDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIA----KE----------------NEIAVL-H-K-I-KHPNIVALDDIYE--S----GGHLYLIMQLVSGGELFDRIVEK----G----F-YTERDASRLIFQVLDAVKYLHD-LGIVHRDLKPENLLYYSL-----DE---D---S----K---IM--ISDF--------------------------TPGYVAPEVLAQKPYS--------KAVDCWSIGVIAYILLCGYPPFYDEND----AK-LFE-QI--LKAEYE--F-DSP----Y----WDD-ISDS--AKD--FIRHLMEKDPEKR-----F-----TC------E-QALQHPWIAGD--------------TALDKNIHQS--VSEQIKK--NFA-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34 PsiBlast_CBE 52.0246% -93 - C4 -4BKZ MELK_HUMAN A:[9-291] -----------------------LKYYELHETIGTG--AKVKLACHILTGEMVAIKIMD----KNTL--------LPR-IKTEIEAL-K-N-L-RHQHICQLYHVLE--T----ANKIFMVLEYCPGGELFDYIISQ----D----R-LSEEETRVVFRQIVSAVAYVHS-QGYAHRDLKPENLL---F-----DE---Y---H----K---LK--LIDFGLCA----------------------SLAYAAPELIQG---------G--SEADVWSMGILLYVLMCGFLPFDDDNV----MA-LYK-KI--MRG--K--Y-DVP----K----W---LSPS--SIL--LLQQMLQVDPKKR-----I-----SM------K-NLLNHPWIMQD-----------------YNYPVEW--QSKNPFIHLDDDCVTELSVHHRNNRQTMEDLISLWQYDHLTATYLLLLAKKARGKPVRLRL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
95 PsiBlast_CBE 51.9937% -99 - C4 -3MWU ? A:[30-282] --------------------------------LGKGSFGEVLKCKDRITQQEYAVKVIN----KASAKNKD---T-ST-ILREVELL-K-K-L-DHPNIMKLFEILE--D----SSSFYIVGELYTGGELFDEIIKR----K----R-FSEHDAARIIKQVFSGITYMHK-HNIVHRDLKPENIL---L-----ES---KEKDC----D---IK--IIDFGLSTC----F-QQN--------DRIGTAYYIAPEVLRGTY-------D--EKCDVWSAGVILYILLSGTPPFYGKNE----YD-ILK-RV--ETGKYA--F-DLP----Q----WRT-ISDD--AKD--LIRKMLTFHPSLR-----I-----TA------T-QCLEHPWIQKY--------------SSETPTISDL--PSLESAM--TNIRQFQAEKKLAQAALLYMASKLTTLDETKQLTEIFRKLDTNNDGMLDRDELVRGYHEFMRLKGVDSNSLIQNEGSTIEDQIDSLMPLLDMDGSGSIEYSEFIASAIDRTILLSRERMERAFKMFDKDGSGKISTKELEQVDNNKDGEVDFNEFVEMLQNFVR------------------------------------------------------------------------------------------------
61 PsiBlast_CBE 51.9035%-105 - C4 -3HX4 ? A:[57-330] -------------------------------VLGKGSFGEVILCKDKITGQECAVKVIS----K----------DKES-LLREVQLL-K-Q-L-DHPNIMKLYEFFE--D----KGYFYLVGEVYTGGELFDEIISR----K----R-FSEVDAARIIRQVLSGITYMHK-NKIVHRDLKPENLL---L-----ES---KSKDA----N---IR--IIDFGLSTH----F-EAS---K-KMKDKIGTAYYIAPEVLHGTY-------D--EKCDVWSTGVILYILLSGCPPFNGANE----YD-ILK-KV--EKGKYT--F-ELP----Q----WKK-VSES--AKD--LIRKMLTYVPSMR-----I-----SA------R-DALDHEWIQTY--------------TKEQISVDVP--SLDNAIL--NIRQFQGTQKLAQAALLYMGSKLTSQDETKELTAIFHKMDKNGDGQLDRAELIEGYKELMRMKGQDASMLDASAVEHEVDQVLDAVDFDKNGYIEYSEFVTVAMDRKTLLSRERLERAFRMFDSDNSGKISSTELATIFGVSDVDSETWKSVLSEVDKNNDGEVDFDEFQQMLLK-------------------------------------------------------------------------------------
132 HHSearch 51.6132% -99 - C4 -4C2V AUKBA_XENLA A:[12-282] --------------------KFTIDDFDIGRPLGKGKFGNVYLAREKQNKFIMALKVLF----KSQLEKEG---VEHQ-LRREIEIQ-S-H-L-RHPNILRMYNYFH--D----RKRIYLMLEFAPRGELYKELQKH----G----R-FDEQRSATFMEELADALHYCHE-RKVIHRDIKPENLL---M-----GY---K---G----E---LK--IADFGWSVH----A-PSL-----RRRTMCGTLDYLPPEMIEGKTH------D--EKVDLWCAGVLCYEFLVGMPPFDSPSH----TE-THR-RI--VNV--D--L-KFP----P----F---LSDG--SKD--LISKLLRYHPPQR-----L-----PL------K-GVMEHPWVKAN--------------SRRVLPPVYQ--S----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
92 PsiBlast_CBE 51.5537% -96 - C4 -3MA6 ? A:[39-292] -------------------------------VLGKGSFGEVILCKDKITGQECAVKVIS----KRQVKQKT---DKES-LLREVQLL-K-Q-L-DHPNIMKLYEFFE--D----KGYFYLVGEVYTGGELFDEIISR----K----R-FSEVDAARIIRQVLSGITYMHK-NKIVHRDLKPENLL---L-----ES---KSKDA----N---IR--IIDFGLSTH----F-E-S---K-KMKDKIGTAYYIAPEVLHGTY-------D--EKCDVWSTGVILYILLSGCPPFNGANE----YD-ILK-KV--EKGKYT--F-ELP----Q----WKK-VSES--AKD--LIRKMLTYVPSMR-----I-----SA------R-DALDHEWIQTY--------------TK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
59 PsiBlast_CBE 51.4135% -92 - C4 -4IFG ? A:[56-329] -------------------------------VLGKGSFGEVILCKDKITGQECAVKVIS----KRQVKQKT---DKES-LLREVQLL-K-Q-L-DHPNIMKLYEFFE--D----KGYFYLVGEVYTGGELFDEIISR----K----R-FSEVDAARIIRQVLSGITYMHK-NKIVHRDLKPENLL---L-----ES---KSKDA----N---IR--IIDFGLSTH----F-EAS---K-KMKDKIGTAYYIAPEVLHGTY-------D--EKCDVWSTGVILYILLSGCPPFNGANE----YD-ILK-KV--EKGKYT--F-ELP----Q----WKK-VSES--AKD--LIRKMLTYVPSMR-----I-----SA------R-DALDHEWIQTY--------------TK-----DVP--SLDNAIL--NIRQFQGTQKLAQAALLYMGSKLTSQDETKELTAIFHKMDKNGDGQLDRAELIEGYKELMRMKGQDASMLDASAVEHEVDQVLDAVDEYSEFVTVAMDRKTLLSRERLERAFRMFDSDNSGKISSTELATIFGVSDVDSETWKSVLSEVDKNNDGEVDFDEFQQMLLKLCGN----------------------------------------------------------------------------------------
94 PsiBlast_CBE 51.1737%-104 - C4 -3NCG ? A:[30-282] --------------------------------LGKGSFGEVLKCKDRITQQEYAVKVIN----KASAKNKD---T-ST-ILREVELL-K-K-L-DHPNIMKLFEILE--D----SSSFYIVGELYTGGELFDEIIKR----K----R-FSEHDAARIIKQVFSGITYMHK-HNIVHRDLKPENIL---L-----ES---KEKDC----D---IK--IIDFGLSTC----F-QQN---T------IGTAYYIAPEVLRGTY-------D--EKCDVWSAGVILYILLSGTPPFYGKNE----YD-ILK-RV--ETGKYA--F-DLP----Q----WRT-ISDD--AKD--LIRKMLTFHPSLR-----I-----TA------T-QCLEHPWIQKY--------------SSETPTISDL--PSLESAM--TNIRQFQAEKKLAQAALLYMASKLTTLDETKQLTEIFRKLDTNNDGMLDRDELVRGYHEFMRLKGVDSNGSTIEDQIDSLMPLLDMDGSGSIEYSEFIASAIDRTILLSRERMERAFKMFDKDGSGKISTKELDFNEFVEMLQN--------------------------------------------------------------------------------------------------------------------
138 HHSearch 51.0733% -93 - C4 -3C0I CSKP_HUMAN A:[24-293] ------------------------DVYELCEVIGKGPFSVVRRCINRETGQQFAVKIVD----VAKFTSSPGL-STED-LKREASIC-H-M-L-KHPHIVELLETYS--S----DGMLYMVFEFMDGADLCFEIVKR----ADAGFV-YSEAVASHYMRQILEALRYCHD-NNIIHRDVKPHCVL---L-----AS---K---E----NSAPVK--LGGFGVAIQ----L-GES---GLVAGGRVGTPHFMAPEVVKREPY------G--KPVDVWGCGVILFILLSGCLPFYGTK-----ER-LFE-GI--IKG--K--Y-KMNPRQWS----H---ISES--AKD--LVRRMLMLDPAER-----I-----TV------Y-EALNHPWLKER--------------DRYAYKIHLP--ETVEQLR--KFNARRK-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
77 PsiBlast_CBE 51.0135% -95 - C4 -3SX9 ? A:[33-306] -------------------------------VLGKGSFGEVILCKDKITGQECAVKVIS----KRQVKQKT---DKES-LLREVQLL-K-Q-L-DHPNIMKLYEFFE--D----KGYFYLVGEVYTGGELFDEIISR----K----R-FSEVDAARIIRQVLSGITYMHK-NKIVHRDLKPENLL---L-----ES---KSKDA----N---IR--IIDFGLSTH----F-EAS---K-KMKDKIGTAYYIAPEVLHGTY-------D--EKCDVWSTGVILYILLSGCPPFNGANE----YD-ILK-KV--EKGKYT--F-ELP----Q----WKK-VSES--AKD--LIRKMLTYVPSMR-----I-----SA------R-DALDHEWIQTY--------------TK-----DVP--SLDNAIL--NIRQFQGTQKLAQAALLYMGSKLTSQDETKELTAIFHKMDKNGDGQLDRAELIEGYKELMRDASMLDASAVEHEVDQVLDAVDFDKNGYIEYSEFVTVAMDRKTLLSRERLERAFRMFDSDNSGKISSTELATIFGVSDVDSETWKSVLSEVDKNNDGEVDFDEFQQMLLKLCGN-------------------------------------------------------------------------------------