@TOME V2.3
(Nov 2016)

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3D Common Core:

Structural Clustering:

Modeller Result :

Complexes Modeling
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Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : AKT1_HUMAN: (2015-10-03 )
MSDVAIVKEGWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERPQDVDQREAPLNNFSVAQCQLMKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREEWTTAIQTVADGLKKQEEEEMDFRSGSPSDNSGAEEMEVSLAKPKHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKSLLSGLLKKDPKQRLGGGSEDAKEIMQHRFFAGIVWQHVYEKKLSPPFKPQVTSETDTRYFDEEFTAQMITITPPDQDDSMECVDSERRPHFPQFSYSASGTA

Atome Classification :

(107 SA) .........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......-160.......---170--.-.----......180.....--.-.190-.........200.-.--.-.-.-...210.......220.......230.......240.--.......250.......260.......270.......280.-...----...290.......300.....--.-.310.......320.-----.---.....330.......340...-....-----350.---.----..---.....360...--....----370.......380.......390...-.-...-400........410---.......420.......430.......440.......450.......460......---.470.......480
(Atome) (Ident) (Tito) (Num) (Ligand) (Uniprot) MSDVAIVKEGWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERPQDVDQREAPLNNFSVAQCQLMKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREEWTTAIQTVADGLKKQEEEEMDFRSGSPSDNSGAEEMEVSLAKPKHRVTMNEFEYLKLLGKG-TFGKVILVKE---KA---T-G----RYYAMKILKKEVIV--A-KD---EVAHTLTENRV-L-Q--N-S-R-HPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSR-E--RVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLD-KDG----HIKITDFGLCKEGIKDGATMK--T-FCGTPEYLAPEVLED-----N---DYGRAVDWWGLGVVMYEMMCG-RLPF-----Y--N---Q----DH---EKLFELILMEE--IRFP----RTLGPEAKSLLSGLLKKDPKQRLGGG-S-EDA-KE-IMQHRFFAGIV---WQHVYEKKLSPPFKPQVTSETDTRYFDEEFTAQMITITPPDQDDSMECVDSERRPH---FPQFSYSASGTA
114 HHSearch 90.4499%-109 - C1 -4EJN AKT1_HUMAN A:[4-438] ---VAIVKEGWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERP-------APLNNFSVAQCQLMKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREEWTTAIQTVADG----------------------------------RVTMNEFEYLKLLGKG-TFGKVILVKE---KA---T-G----RYYAMKILKKEVIV-------------------V-L-Q--N-S-R-HPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSR-E--RVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLD-KDG----HIKITDFGLCKEGIK-----K--T-FCGTPEYLAPEVLED-----N---DYGRAVDWWGLGVVMYEMMCG-RLPF-----Y--N---Q----DH---EKLFELILMEE--IRFP----RTLGPEAKSLLSGLLKKDPKQRLGGG-S-EDA-KE-IMQHRFFAGIV---WQHVYEKKLSPPFKPQVTSETDTRYF---------------------------------------------
3 PsiBlast_PDB 80.5299%-104 - C1 -3OCB AKT1_HUMAN A:[5-339] -----------------------------------------------------------------------------------------------------------------------------------------------RVTMNEFEYLKLLGKG-TFGKVILVKE---KA---T-G----RYYAMKILKKEVIV--A-KD---EVAHTLTENRV-L-Q--N-S-R-HPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSR-E--RVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLD-KDG----HIKITDFGLCKEGIKDGATMK--T-FCGTPEYLAPEVLED-----N---DYGRAVDWWGLGVVMYEMMCG-RLPF-----Y--N---Q----DH---EKLFELILMEE--IRFP----RTLGPEAKSLLSGLLKKDPKQRLGGG-S-EDA-KE-IMQHRFFAGIV---WQHVYEKKLSPPFKPQVTSETDTRYFDEEFTAQM-------------------RPH---FPQFDYSASS--
6 PsiBlast_PDB 80.2299%-104 - C1 -3QKL AKT1_HUMAN A:[5-339] -----------------------------------------------------------------------------------------------------------------------------------------------RVTMNEFEYLKLLGKG-TFGKVILVKE---KA---T-G----RYYAMKILKKEVIV--A-KD---EVAHTLTENRV-L-Q--N-S-R-HPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSR-E--RVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLD-KDG----HIKITDFGLCKEGIKDGATMK--T-FCGTPEYLAPEVLED-----N---DYGRAVDWWGLGVVMYEMMCG-RLPF-----Y--N---Q----DH---EKLFELILMEE--IRFP----RTLGPEAKSLLSGLLKKDPKQRLGGG-S-EDA-KE-IMQHRFFAGIV---WQHVYEKKLSPPFKPQVTSETDTRYFDEEFTAQMIT-----------------RPH---FPQFDYSASS--
10 PsiBlast_PDB 80.1199%-105 - C1 -4GV1 AKT1_HUMAN A:[4-337] -----------------------------------------------------------------------------------------------------------------------------------------------RVTMNEFEYLKLLGKG-TFGKVILVKE---KA---T-G----RYYAMKILKKEVIV--A-KD---EVAHTLTENRV-L-Q--N-S-R-HPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSR-E--RVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLD-KDG----HIKITDFGLCKEGIKDGATMK--T-FCGTPEYLAPEVLED-----N---DYGRAVDWWGLGVVMYEMMCG-RLPF-----Y--N---Q----DH---EKLFELILMEE--IRFP----RTLGPEAKSLLSGLLKKDPKQRLGGG-S-EDA-KE-IMQHRFFAGIV---WQHVYEKKLSPPFKPQVTSETDTRYFDEEFTAQMITITP-----SMECVDSERRPH---FPQFDYSAS---
115 HHSearch 80.0399%-105 - C1 -4GV1 AKT1_HUMAN A:[3-337] ----------------------------------------------------------------------------------------------------------------------------------------------SRVTMNEFEYLKLLGKG-TFGKVILVKE---KA---T-G----RYYAMKILKKEVIV--A-KD---EVAHTLTENRV-L-Q--N-S-R-HPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSR-E--RVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLD-KDG----HIKITDFGLCKEGIKDGATMK--T-FCGTPEYLAPEVLED-----N---DYGRAVDWWGLGVVMYEMMCG-RLPF-----Y--N---Q----DH---EKLFELILMEE--IRFP----RTLGPEAKSLLSGLLKKDPKQRLGGG-S-EDA-KE-IMQHRFFAGIV---WQHVYEKKLSPPFKPQVTSETDTRYFDEEFTAQMITITP-----SMECVDSERRPH---FPQFDYSAS---
11 PsiBlast_PDB 79.5999%-105 - C1 -3CQW AKT1_HUMAN A:[6-340] -----------------------------------------------------------------------------------------------------------------------------------------------RVTMNEFEYLKLLGKG-TFGKVILVKE---KA---T-G----RYYAMKILKKEVIV--A-KD---EVAHTLTENRV-L-Q--N-S-R-HPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSR-E--RVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLD-KDG----HIKITDFGLCKEGIKDGATMK--T-FCGTPEYLAPEVLED-----N---DYGRAVDWWGLGVVMYEMMCG-RLPF-----Y--N---Q----DH---EKLFELILMEE--IRFP----RTLGPEAKSLLSGLLKKDPKQRLGGG-S-EDA-KE-IMQHRFFAGIV---WQHVYEKKLSPPFKPQVTSETDTRYFDEEFTAQMI----------------ERRPH---FPQFDYSASS--
13 PsiBlast_PDB 79.3799%-102 - C1 -3MVH AKT1_HUMAN A:[7-338] ------------------------------------------------------------------------------------------------------------------------------------------------VTMNEFEYLKLLGKG-TFGKVILVKE---KA---T-G----RYYAMKILKKEVIV--A-KD---EVAHTLTENRV-L-Q--N-S-R-HPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSR-E--RVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLD-KDG----HIKITDFGLCKEGIKDGATMK--T-FCGTPEYLAPEVLED-----N---DYGRAVDWWGLGVVMYEMMCG-RLPF-----Y--N---Q----DH---EKLFELILMEE--IRFP----RTLGPEAKSLLSGLLKKDPKQRLGGG-S-EDA-KE-IMQHRFFAGIV---WQHVYEKKLSPPFKPQVTSETDTRYFDEEFTAQ--------------------RPH---FPQFDYSA----
22 PsiBlast_CBE 78.9399%-105 - C1 -3OW4 AKT1_HUMAN B:[5-339] -----------------------------------------------------------------------------------------------------------------------------------------------RVTMNEFEYLKLLGKG-TFGKVILVKE---KA---T-G----RYYAMKILKKEVIV--A-KD---EVAHTLTENRV-L-Q--N-S-R-HPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSR-E--RVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLD-KDG----HIKITDFGLCKEGIKDGATMK--T-FCGTPEYLAPEVLED-----N---DYGRAVDWWGLGVVMYEMMCG-RLPF-----Y--N---Q----DH---EKLFELILMEE--IRFP----RTLGPEAKSLLSGLLKKDPKQRLGGG-S-EDA-KE-IMQHRFFAGIV---WQHVYEKKLSPPFKPQVTSETDTRYFDEEFTAQMIT-----------------RPH---FPQFDYSASS--
12 PsiBlast_PDB 78.8599%-102 - C1 -3MV5 AKT1_HUMAN A:[6-339] -----------------------------------------------------------------------------------------------------------------------------------------------RVTMNEFEYLKLLGKG-TFGKVILVKE---KA---T-G----RYYAMKILKKEVIV--A-KD---EVAHTLTENRV-L-Q--N-S-R-HPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSR-E--RVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLD-KDG----HIKITDFGLCKEGIKDGATMK--T-FCGTPEYLAPEVLED-----N---DYGRAVDWWGLGVVMYEMMCG-RLPF-----Y--N---Q----DH---EKLFELILMEE--IRFP----RTLGPEAKSLLSGLLKKDPKQRLGGG-S-EDA-KE-IMQHRFFAGIV---WQHVYEKKLSPPFKPQVTSETDTRYFDEEFTAQMI------------------RPH---FPQFDYSAS---
21 PsiBlast_CBE 78.5599%-104 - C1 -4EKK AKT1_HUMAN B:[5-338] -----------------------------------------------------------------------------------------------------------------------------------------------RVTMNEFEYLKLLGKG-TFGKVILVKE---KA---T-G----RYYAMKILKKEVIV--A-KD---EVAHTLTENRV-L-Q--N-S-R-HPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSR-E--RVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLD-KDG----HIKITDFGLCKEGIKDGATMK--T-FCGTPEYLAPEVLED-----N---DYGRAVDWWGLGVVMYEMMCG-RLPF-----Y--N---Q----DH---EKLFELILMEE--IRFP----RTLGPEAKSLLSGLLKKDPKQRLGGG-S-EDA-KE-IMQHRFFAGIV---WQHVYEKKLSPPFKPQVTSETDTRYFDEEFTAQMI---------------SERRPH---FPQFDYSAS---
29 PsiBlast_CBE 78.2483%-105 - C1 -2JDO AKT2_HUMAN A:[6-340] -----------------------------------------------------------------------------------------------------------------------------------------------KVTMNDFDYLKLLGKG-TFGKVILVRE---KA---T-G----RYYAMKILRKEVII--A-KD---EVAHTVTESRV-L-Q--N-T-R-HPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSR-E--RVFTEERARFYGAEIVSALEYLHS-RDVVYRDIKLENLMLD-KDG----HIKITDFGLCKEGISDGATMK--T-FCGTPEYLAPEVLED-----N---DYGRAVDWWGLGVVMYEMMCG-RLPF-----Y--N---Q----DH---ERLFELILMEE--IRFP----RTLSPEAKSLLAGLLKKDPKQRLGGG-P-SDA-KE-VMEHRFFLSIN---WQDVVQKKLLPPFKPQVTSEVDTRYFDDEFTAQSIT--------------------M--FEDFDYIADW--
23 PsiBlast_CBE 78.1099%-105 - C1 -3OCB AKT1_HUMAN B:[5-339] -----------------------------------------------------------------------------------------------------------------------------------------------RVTMNEFEYLKLLGKG-TFGKVILVKE---KA---T-G----RYYAMKILKKEVIV--A-KD---EVAHTLTENRV-L-Q--N-S-R-HPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSR-E--RVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLD-KDG----HIKITDFGLCKEGIKDGATMK--T-FCGTPEYLAPEVLED-----N---DYGRAVDWWGLGVVMYEMMCG-RLPF-----Y--N---Q----DH---EKLFELILMEE--IRFP----RTLGPEAKSLLSGLLKKDPKQRLGGG-S-EDA-KE-IMQHRFFAGIV---WQHVYEKKLSPPFKPQVTSETDTRYFDEEFTAQMITIT---------------RPH---FPQFDYSASS--
4 PsiBlast_PDB 77.4099%-102 - C1 -3OW4 AKT1_HUMAN A:[5-339] -----------------------------------------------------------------------------------------------------------------------------------------------RVTMNEFEYLKLLGKG-TFGKVILVKE---KA---T-G----RYYAMKILKKEVIV--A-KD---EVAHTLTENRV-L-Q--N-S-R-HPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSR-E--RVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLD-KDG----HIKITDFGLCKEGIKDGATMK--T-FCGTPEYLAPEVLED-----N---DYGRAVDWWGLGVVMYEMMCG-RLPF-----Y--N---Q----DH---EKLFELILMEE--IRFP----RTLGPEAKSLLSGLLKKDPKQRLGGG-S-EDA-KE-IMQHRFFAGIV---WQHVYEKKLSPPFKPQVTSETDTRYFDEEFTAQMIT-----------------RPH---FPQFDYSASS--
7 PsiBlast_PDB 77.2899%-104 - C1 -3QKM AKT1_HUMAN A:[5-339] -----------------------------------------------------------------------------------------------------------------------------------------------RVTMNEFEYLKLLGKG-TFGKVILVKE---KA---T-G----RYYAMKILKKEVIV--A-KD---EVAHTLTENRV-L-Q--N-S-R-HPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSR-E--RVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLD-KDG----HIKITDFGLCKEGIKDGATMK--T-FCGTPEYLAPEVLED-----N---DYGRAVDWWGLGVVMYEMMCG-RLPF-----Y--N---Q----DH---EKLFELILMEE--IRFP----RTLGPEAKSLLSGLLKKDPKQRLGGG-S-EDA-KE-IMQHRFFAGIV---WQHVYEKKLSPPFKPQVTSETDTRYFDEEFTAQMITITP-----SMECVDSERRPH---FPQFDYSASS--
9 PsiBlast_PDB 77.0499%-103 - C1 -4EKL AKT1_HUMAN A:[5-339] -----------------------------------------------------------------------------------------------------------------------------------------------RVTMNEFEYLKLLGKG-TFGKVILVKE---KA---T-G----RYYAMKILKKEVIV--A-KD---EVAHTLTENRV-L-Q--N-S-R-HPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSR-E--RVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLD-KDG----HIKITDFGLCKEGIKDGATMK--T-FCGTPEYLAPEVLED-----N---DYGRAVDWWGLGVVMYEMMCG-RLPF-----Y--N---Q----DH---EKLFELILMEE--IRFP----RTLGPEAKSLLSGLLKKDPKQRLGGG-S-EDA-KE-IMQHRFFAGIV---WQHVYEKKLSPPFKPQVTSETDTRYFDEEFTAQMITITP-----SMECVDSERRPH---FPQFDYSASS--
17 PsiBlast_PDB 77.0385%-107 - C1 -3E88 AKT2_HUMAN A:[1-333] -----------------------------------------------------------------------------------------------------------------------------------------------KVTMNDFDYLKLLGKG-TFGKVILVRE---KA---T-G----RYYAMKILRKEVII--A-KD---EVAHTVTESRV-L-Q--N-T-R-HPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSR-E--RVFTEERARFYGAEIVSALEYLHS-RDVVYRDIKLENLMLD-KDG----HIKITDFGLCKEGISDGATMK--T-FCGTPEYLAPEVLED-----N---DYGRAVDWWGLGVVMYEMMCG-RLPF-----Y--N---Q----DH---ERLFELILMEE--IRFP----RTLSPEAKSLLAGLLKKDPKQRLGGG-P-SDA-KE-VMEHRFFLSIN---WQDVVQKKLLPPFKPQVTSEVDTRYFDDEFTAQSITIT--------------QRTH---FPQFDYSASIR-
5 PsiBlast_PDB 76.7999%-102 - C1 -3QKK AKT1_HUMAN A:[5-339] -----------------------------------------------------------------------------------------------------------------------------------------------RVTMNEFEYLKLLGKG-TFGKVILVKE---KA---T-G----RYYAMKILKKEVIV--A-KD---EVAHTLTENRV-L-Q--N-S-R-HPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSR-E--RVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLD-KDG----HIKITDFGLCKEGIKDGATMK--T-FCGTPEYLAPEVLED-----N---DYGRAVDWWGLGVVMYEMMCG-RLPF-----Y--N---Q----DH---EKLFELILMEE--IRFP----RTLGPEAKSLLSGLLKKDPKQRLGGG-S-EDA-KE-IMQHRFFAGIV---WQHVYEKKLSPPFKPQVTSETDTRYFDEEFTAQMITI--------MECVDSERRPH---FPQFDYSASS--
8 PsiBlast_PDB 76.7699%-101 - C1 -4EKK AKT1_HUMAN A:[5-338] -----------------------------------------------------------------------------------------------------------------------------------------------RVTMNEFEYLKLLGKG-TFGKVILVKE---KA---T-G----RYYAMKILKKEVIV--A-KD---EVAHTLTENRV-L-Q--N-S-R-HPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSR-E--RVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLD-KDG----HIKITDFGLCKEGIKDGATMK--T-FCGTPEYLAPEVLED-----N---DYGRAVDWWGLGVVMYEMMCG-RLPF-----Y--N---Q----DH---EKLFELILMEE--IRFP----RTLGPEAKSLLSGLLKKDPKQRLGGG-S-EDA-KE-IMQHRFFAGIV---WQHVYEKKLSPPFKPQVTSETDTRYFDEEFTAQMI---------------SERRPH---FPQFDYSAS---
16 PsiBlast_PDB 76.4085%-107 - C1 -3E87 AKT2_HUMAN A:[1-333] -----------------------------------------------------------------------------------------------------------------------------------------------KVTMNDFDYLKLLGKG-TFGKVILVRE---KA---T-G----RYYAMKILRKEVII--A-KD---EVAHTVTESRV-L-Q--N-T-R-HPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSR-E--RVFTEERARFYGAEIVSALEYLHS-RDVVYRDIKLENLMLD-KDG----HIKITDFGLCKEGISDGATMK--T-FCGTPEYLAPEVLED-----N---DYGRAVDWWGLGVVMYEMMCG-RLPF-----Y--N---Q----DH---ERLFELILMEE--IRFP----RTLSPEAKSLLAGLLKKDPKQRLGGG-P-SDA-KE-VMEHRFFLSIN---WQDVVQKKLLPPFKPQVTSEVDTRYFDDEFTAQSITITPP------------QRTH---FPQFDYSASIR-
15 PsiBlast_PDB 76.1085%-107 - C1 -1O6K AKT2_HUMAN A:[1-333] -----------------------------------------------------------------------------------------------------------------------------------------------KVTMNDFDYLKLLGKG-TFGKVILVRE---KA---T-G----RYYAMKILRKEVII--A-KD---EVAHTVTESRV-L-Q--N-T-R-HPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSR-E--RVFTEERARFYGAEIVSALEYLHS-RDVVYRDIKLENLMLD-KDG----HIKITDFGLCKEGISDGATMK--T-FCGTPEYLAPEVLED-----N---DYGRAVDWWGLGVVMYEMMCG-RLPF-----Y--N---Q----DH---ERLFELILMEE--IRFP----RTLSPEAKSLLAGLLKKDPKQRLGGG-P-SDA-KE-VMEHRFFLSIN---WQDVVQKKLLPPFKPQVTSEVDTRYFDDEFTAQSIT----------------QRTH---FPQFDYSASI--
24 PsiBlast_CBE 75.7085%-106 - C1 -3E8D AKT2_HUMAN B:[1-333] -----------------------------------------------------------------------------------------------------------------------------------------------KVTMNDFDYLKLLGKG-TFGKVILVRE---KA---T-G----RYYAMKILRKEVII--A-KD---EVAHTVTESRV-L-Q--N-T-R-HPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSR-E--RVFTEERARFYGAEIVSALEYLHS-RDVVYRDIKLENLMLD-KDG----HIKITDFGLCKEGISDGATMK--T-FCGTPEYLAPEVLED-----N---DYGRAVDWWGLGVVMYEMMCG-RLPF-----Y--N---Q----DH---ERLFELILMEE--IRFP----RTLSPEAKSLLAGLLKKDPKQRLGGG-P-SDA-KE-VMEHRFFLSIN---WQDVVQKKLLPPFKPQVTSEVDTRYFDDEFTAQSI-----------------QRTH---FPQFDYSASIR-
27 PsiBlast_CBE 75.3783%-104 - C1 -2UW9 AKT2_HUMAN A:[6-340] -----------------------------------------------------------------------------------------------------------------------------------------------KVTMNDFDYLKLLGKG-TFGKVILVRE---KA---T-G----RYYAMKILRKEVII--A-KD---EVAHTVTESRV-L-Q--N-T-R-HPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSR-E--RVFTEERARFYGAEIVSALEYLHS-RDVVYRDIKLENLMLD-KDG----HIKITDFGLCKEGISDGATMK--T-FCGTPEYLAPEVLED-----N---DYGRAVDWWGLGVVMYEMMCG-RLPF-----Y--N---Q----DH---ERLFELILMEE--IRFP----RTLSPEAKSLLAGLLKKDPKQRLGGG-P-SDA-KE-VMEHRFFLSIN---WQDVVQKKLLPPFKPQVTSEVDTRYFDDEFTAQSIT--------------------QEMFEDFDYIADW--
18 PsiBlast_PDB 75.2085%-107 - C1 -3E8D AKT2_HUMAN A:[1-333] -----------------------------------------------------------------------------------------------------------------------------------------------KVTMNDFDYLKLLGKG-TFGKVILVRE---KA---T-G----RYYAMKILRKEVII--A-KD---EVAHTVTESRV-L-Q--N-T-R-HPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSR-E--RVFTEERARFYGAEIVSALEYLHS-RDVVYRDIKLENLMLD-KDG----HIKITDFGLCKEGISDGATMK--T-FCGTPEYLAPEVLED-----N---DYGRAVDWWGLGVVMYEMMCG-RLPF-----Y--N---Q----DH---ERLFELILMEE--IRFP----RTLSPEAKSLLAGLLKKDPKQRLGGG-P-SDA-KE-VMEHRFFLSIN---WQDVVQKKLLPPFKPQVTSEVDTRYFDDEFTAQSIT-------------------H---FPQFDYSASIR-
20 PsiBlast_PDB 75.0283%-107 - C1 -1O6L AKT2_HUMAN A:[1-335] -----------------------------------------------------------------------------------------------------------------------------------------------KVTMNDFDYLKLLGKG-TFGKVILVRE---KA---T-G----RYYAMKILRKEVII--A-KD---EVAHTVTESRV-L-Q--N-T-R-HPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSR-E--RVFTEERARFYGAEIVSALEYLHS-RDVVYRDIKLENLMLD-KDG----HIKITDFGLCKEGISDGATMK--T-FCGTPEYLAPEVLED-----N---DYGRAVDWWGLGVVMYEMMCG-RLPF-----Y--N---Q----DH---ERLFELILMEE--IRFP----RTLSPEAKSLLAGLLKKDPKQRLGGG-P-SDA-KE-VMEHRFFLSIN---WQDVVQKKLLPPFKPQVTSEVDTRYFDDEFTAQSIT--------------------QEMFEDFDYIADW--
26 PsiBlast_CBE 74.4583%-105 - C1 -2X39 AKT2_HUMAN A:[6-340] -----------------------------------------------------------------------------------------------------------------------------------------------KVTMNDFDYLKLLGKG-TFGKVILVRE---KA---T-G----RYYAMKILRKEVII--A-KD---EVAHTVTESRV-L-Q--N-T-R-HPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSR-E--RVFTEERARFYGAEIVSALEYLHS-RDVVYRDIKLENLMLD-KDG----HIKITDFGLCKEGISDGATMK--T-FCGTPEYLAPEVLED-----N---DYGRAVDWWGLGVVMYEMMCG-RLPF-----Y--N---Q----DH---ERLFELILMEE--IRFP----RTLSPEAKSLLAGLLKKDPKQRLGGG-P-SDA-KE-VMEHRFFLSIN---WQDVVQKKLLPPFKPQVTSEVDTRYFDDEFTAQSIT--------------------QEMFEDFDYIADW--
28 PsiBlast_CBE 74.1783%-105 - C1 -2JDR AKT2_HUMAN A:[6-340] -----------------------------------------------------------------------------------------------------------------------------------------------KVTMNDFDYLKLLGKG-TFGKVILVRE---KA---T-G----RYYAMKILRKEVII--A-KD---EVAHTVTESRV-L-Q--N-T-R-HPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSR-E--RVFTEERARFYGAEIVSALEYLHS-RDVVYRDIKLENLMLD-KDG----HIKITDFGLCKEGISDGATMK--T-FCGTPEYLAPEVLED-----N---DYGRAVDWWGLGVVMYEMMCG-RLPF-----Y--N---Q----DH---ERLFELILMEE--IRFP----RTLSPEAKSLLAGLLKKDPKQRLGGG-P-SDA-KE-VMEHRFFLSIN---WQDVVQKKLLPPFKPQVTSEVDTRYFDDEFTAQSIT--------------------QEMFEDFDYIADW--
25 PsiBlast_CBE 73.7683%-109 - C1 -2XH5 AKT2_HUMAN A:[6-340] -----------------------------------------------------------------------------------------------------------------------------------------------KVTMNDFDYLKLLGKG-TFGKVILVRE---KA---T-G----RYYAMKILRKEVII--A-KD---EVAHTVTESRV-L-Q--N-T-R-HPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSR-E--RVFTEERARFYGAEIVSALEYLHS-RDVVYRDIKLENLMLD-KDG----HIKITDFGLCKEGISDGATMK--T-FCGTPEYLAPEVLED-----N---DYGRAVDWWGLGVVMYEMMCG-RLPF-----Y--N---Q----DH---ERLFELILMEE--IRFP----RTLSPEAKSLLAGLLKKDPKQRLGGG-P-SDA-KE-VMEHRFFLSIN---WQDVVQKKLLPPFKPQVTSEVDTRYFDDEFTAQSIT--------------------QEMFEDFDYIADW--
19 PsiBlast_PDB 73.4985%-107 - C1 -3D0E AKT2_HUMAN A:[1-333] -----------------------------------------------------------------------------------------------------------------------------------------------KVTMNDFDYLKLLGKG-TFGKVILVRE---KA---T-G----RYYAMKILRKEVII--A-KD---EVAHTVTESRV-L-Q--N-T-R-HPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSR-E--RVFTEERARFYGAEIVSALEYLHS-RDVVYRDIKLENLMLD-KDG----HIKITDFGLCKEGISDGATMK--T-FCGTPEYLAPEVLED-----N---DYGRAVDWWGLGVVMYEMMCG-RLPF-----Y--N---Q----DH---ERLFELILMEE--IRFP----RTLSPEAKSLLAGLLKKDPKQRLGGG-P-SDA-KE-VMEHRFFLSIN---WQDVVQKKLLPPFKPQVTSEVDTRYFDDEFTAQSITITPPD-----------QRTH---FPQFDYSASIR-
124 HHSearch 58.4845% -93 - C1 -4DC2 KPCI_MOUSE A:[49-387] ------------------------------------------------------------------------------------------------------------------------------------------------LGLQDFDLLRVIGRG-SYAKVLLVRL---KK---T-D----RIYAMRVVKKELVN----------IDWVQTEKHV-F-E--Q-ASN-HPFLVGLHSCFQTESRLFFVIEYVNGGDLMFHMQR-Q--RKLPEEHARFYSAEISLALNYLHER-GIIYRDLKLDNVLLD-SEG----HIKLTDYGMCKEGLRPGDTTS--T-FCGTPNYIAPEILRG-----E---DYGFSVDWWALGVLMFEMMAG-RSPF-----D--IVGSN----TE---DYLFQVILEKQ--IRIP----RSLSVKAASVLKSFLNKDPKERLGCHPQ-TGF-AD-IQGHPFFRNVD---WDMMEQKQVVPPFKPNISGEFGLDNFDSQFTNEPVQLTPDDDD-IVRKID---QSE---FEGFEYINP---
36 PsiBlast_CBE 57.6145% -89 - C1 -4L43 KS6B1_HUMAN A:[10-344] -------------------------------------------------------------------------------------------------------------------------------------------RGPEKIRPECFELLRVLGKG-GYGKVFQVRKVTGAN---T-G----KIFAMKVLKKAMIVRNA-KD----TAHTKAERNI-L-E--E-V-K-HPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLER-E--GIFMEDTACFYLAEISMALGHLH-QKGIIYRDLKPENIMLN-HQG----HVKLTDFGLCKES--------------GTIEYMAPEILMR-----S---GHNRAVDWWSLGALMYDMLTG-APPF-----T--G---E----NR---KKTIDKILKCK--LNLP----PYLTQEARDLLKKLLKRNAASRLGAG-P-GDA-GE-VQAHPFFRHIN---WEELLARKVEPPFKPLLQSEEDVSQFDSKFTRQ----TPV----------SANQV----FLGFAYVAPS--
126 HHSearch 57.1243% -88 - C1 -1RDQ KAPCA_MOUSE E:[36-338] ----------------------------------------------------------------------------------------------------------------------------------------------NTAQLDQFDRIKTLGTG-SFGRVMLVKH---KE---S-G----NHYAMKILDKQKVV--K-LK---QIEHTLNEKRI-L-Q--A-V-N-FPFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRR-I--GRFSEPHARFYAAQIVLTFEYLHSL-DLIYRDLKPENLLID-QQG----YIQVTDFGFAKRVK---GRTW--T-LCGTPEALAPEIILS-----K---GYNKAVDWWALGVLIYEMAAG-YPPF-----F--A---D----QP---IQIYEKIVSGK--VRFP----SHFSSDLKDLLRNLLQVDLTKRFGNL-K-NGV-ND-IKNHKWFATTD---WIAIYQRKVEAPFIPKFKGPGDTSNFDD-YEEEEIRVSINEKCGKEFTEF---------------------
121 HHSearch 56.9445%-103 - C1 -1XJD A:[16-335] --------------------------------------------------------------------------------------------------------------------------------------------------IEDFILHKMLGKG-SFGKVFLAEF---KK---T-N----QFFAIKALKKDVVL--M-DD---DVECTMVEKRV-L-S--LAW-E-HPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQS-C--HKFDLSRATFYAAEIILGLQFLHSK-GIVYRDLKLDNILLD-KDG----HIKIADFGMCKENMLGDAKTN--T-FCGTPDYIAPEILLG-----Q---KYNHSVDWWSFGVLLYEMLIG-QSPF-----H--G---Q----DE---EELFHSIRMDN--PFYP----RWLEKEAKDLLVKLFVREPEKRLGVR-------GD-IRQHPLFREIN---WEELERKEIDP------------------------------------------QNM---FRNFSF------
42 PsiBlast_CBE 56.7547% -96 - C1 -4RA5 KPCT_HUMAN A:[1-298] -----------------------------------------------------------------------------------------------------------------------------------------------KLKIEDFELHKMLGKG-SFGKVFLAEF---KK---T-N----QFFAIKALKKDVVL--M-DD---DVECTMVEKRV-L-S--L-AWE-HPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQS-C--HKFDLSRATFYAAEIILGLQFLHS-KGIVYRDLKLDNILLD-KDG----HIKIADFGMCKENMLGDAKTN--E-FCGTPDYIAPEILLG-----Q---KYNHSVDWWSFGVLLYEMLIG-QSPF-----H--G---Q----DE---EELFHSIRMDN--PFYP----RWLEKEAKDLLVKLFVREPEKRLGVR-G------D-IRQHPLFREIN---WEELERKEIDPPFRPKVKSPFDCSNFDKEFLNEKPRLSFADRALINSMDQNMFRNF---SFMNPGMERLIS
34 PsiBlast_CBE 56.7244% -98 - C1 -4DC2 KPCI_MOUSE A:[49-384] ------------------------------------------------------------------------------------------------------------------------------------------------LGLQDFDLLRVIGRG-SYAKVLLVRL---KK---T-D----RIYAMRVVKKELVN----------IDWVQTEKHV-FEQ--A-S-N-HPFLVGLHSCFQTESRLFFVIEYVNGGDLMFHMQR-Q--RKLPEEHARFYSAEISLALNYLH-ERGIIYRDLKLDNVLLD-SEG----HIKLTDYGMCKEGLRPGDTTS--T-FCGTPNYIAPEILRG-----E---DYGFSVDWWALGVLMFEMMAG-RSPFDIVGS--------------NTEDYLFQVILEKQ--IRIP----RSLSVKAASVLKSFLNKDPKERLGCH-P-QTGFAD-IQGHPFFRNVD---WDMMEQKQVVPPFKPNISGEFGLDNFDSQFTNEPVQLT-PDDDDIVRKID---QSE---FEGFEYINP---
43 PsiBlast_CBE 56.7147% -93 - C1 -4Q9Z KPCT_HUMAN A:[2-298] ------------------------------------------------------------------------------------------------------------------------------------------------LKIEDFELHKMLGKG-SFGKVFLAEF---KK---T-N----QFFAIKALKKDVVL--M-DD---DVECTMVEKRV-L-S--L-AWE-HPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQS-C--HKFDLSRATFYAAEIILGLQFLHS-KGIVYRDLKLDNILLD-KDG----HIKIADFGMCKENMLGDAKTN--E-FCGTPDYIAPEILLG-----Q---KYNHSVDWWSFGVLLYEMLIG-QSPF-----H--G---Q----DE---EELFHSIRMDN--PFYP----RWLEKEAKDLLVKLFVREPEKRLGVR-G------D-IRQHPLFREIN---WEELERKEIDPPFRPKVKSPFDCSNFDKEFLNEKPRLSFADRALINSMDQNMFRNF---SFMNPGMERLIS
37 PsiBlast_CBE 56.1345% -95 - C1 -4L42 KS6B1_HUMAN A:[13-344] ----------------------------------------------------------------------------------------------------------------------------------------------EKIRPECFELLRVLGKG-GYGKVFQVRKVTGAN---T-G----KIFAMKVLKKAMIVRNA-KD----TAHTKAERNI-L-E--E-V-K-HPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLER-E--GIFMEDTACFYLAEISMALGHLH-QKGIIYRDLKPENIMLN-HQG----HVKLTDFGLCKESIHDGTVTH--T-FCGTIEYMAPEILMR-----S---GHNRAVDWWSLGALMYDMLTG-APPF-----T--G---E----NR---KKTIDKILKCK--LNLP----PYLTQEARDLLKKLLKRNAASRLGAG-P-GDA-GE-VQAHPFFRHIN---WEELLARKVEPPFK----------------------------------------EM---FRDFEYIADW--
125 HHSearch 55.7437% -86 - C1 -4AW2 MRCKA_RAT A:[69-406] ----------------------------------------------------------------------------------------------------------------------------------------------MRLHREDFEILKVIGRG-AFGEVAVVKL---KN---A-D----KVFAMKILNKWEML--K-RA---ETACFREERDV-L-V--N-G-D-SKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSKFE--DRLPEEMARFYLAEMVIAIDSVHQL-HYVHRDIKPDNILMD-MNG----HIRLADFGSCLKLMEDGTVQS--SVAVGTPDYISPEILQAMEGGKG---RYGPECDWWSLGVCMYEMLYG-ETPF-----Y--A---E----SL---VETYGKIMNHKERFQFPTQV-TDVSENAKDLIRRLIC-SREHRLG---Q-NGI-ED-FKKHPFFSGID---WDNI--RNCEAPYIPEVSSPTDTSNFDVD---------------------SGHHLP---FVGFTYTSSCVL
117 HHSearch 55.0249%-108 - C1 -2R5T SGK1_HUMAN A:[32-320] ---------------------------------------------------------------------------------------------------------------------------------------------NPHAKPSDFHFLKVIGKG-SFGKVLLARH---KA---E-E----VFYAVKVLQKKAIL-------------------VLL-K--N-V-K-HPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQR-E--RCFLEPRARFYAAEIASALGYLHSL-NIVYRDLKPENILLD-SQG----HIVLTDFGLCKENIEHNSTTS--T-FCGTPEYLAPEVLHK-----Q---PYDRTVDWWCLGAVLYEMLYG-LPPF-----Y--S---R----NT---AEMYDNILNKP--LQLK----PNITNSARHLLEGLLQKDRTKRLGA--K-DDF-ME-IKSHVFFSLIN---WDDLINKKITPPFNPNVSG----------------------------------------------------
62 PsiBlast_CBE 54.6545% -87 - C1 -2UW7 KAPCA_BOVIN A:[41-330] --------------------------------------------------------------------------------------------------------------------------------------------------LDQFERIKTLGTG-SFGRVMLVKH---ME---T-G----NHYAMKILDKQKVV--K-LK---QIEHTLNEKRI-L-Q--A-V-N-FPFLTKLEFSFKDNSNLYMVMEYAPGGEMFSHLRR-I--GRFSEPHARFYAAQIVLTFEYLHS-LDLIYRDLKPENLMID-QQG----YIKVTDFGFAKR--VKGRTWT----LCGTPEYLAPEIILS-----K---GYNKAVDWWALGVLIYEMAAG-YPPF-----F--A---D----QP---IQIYEKIVSGK--VRFP----SHFSSDLKDLLRNLLQVDLTKRFGNL-K-NGV-ND-IKNHKWFATTD---WIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF----------------------
66 PsiBlast_CBE 54.3245% -87 - C1 -2JDT KAPCA_BOVIN A:[41-330] --------------------------------------------------------------------------------------------------------------------------------------------------LDQFERIKTLGTG-SFGRVMLVKH---ME---T-G----NHYAMKILDKQKVV--K-LK---QIEHTLNEKRI-L-Q--A-V-N-FPFLTKLEFSFKDNSNLYMVMEYAPGGEMFSHLRR-I--GRFSEPHARFYAAQIVLTFEYLHS-LDLIYRDLKPENLMID-QQG----YIKVTDFGFAKR--VKGRTWT----LCGTPEYLAPEIILS-----K---GYNKAVDWWALGVLIYEMAAG-YPPF-----F--A---D----QP---IQIYEKIVSGK--VRFP----SHFSSDLKDLLRNLLQVDLTKRFGNL-K-NGV-ND-IKNHKWFATTD---WIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF----------------------
61 PsiBlast_CBE 54.3145% -86 - C1 -4AXA KAPCA_BOVIN A:[41-330] --------------------------------------------------------------------------------------------------------------------------------------------------LDQFERIKTLGTG-SFGRVMLVKH---ME---T-G----NHYAMKILDKQKVV--K-LK---QIEHTLNEKRI-L-Q--A-V-N-FPFLTKLEFSFKDNSNLYMVMEYAPGGEMFSHLRR-I--GRFSEPHARFYAAQIVLTFEYLHS-LDLIYRDLKPENLMID-QQG----YIKVTDFGFAKR--VKGRTWT----LCGTPEYLAPEIILS-----K---GYNKAVDWWALGVLIYEMAAG-YPPF-----F--A---D----QP---IQIYEKIVSGK--VRFP----SHFSSDLKDLLRNLLQVDLTKRFGNL-K-NGV-ND-IKNHKWFATTD---WIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF----------------------
35 PsiBlast_CBE 53.9145% -85 - C1 -4L44 KS6B1_HUMAN A:[10-344] -------------------------------------------------------------------------------------------------------------------------------------------RGPEKIRPECFELLRVLGKG-GYGKVFQVRKVTGAN---T-G----KIFAMKVLKKAMIVRNA-KD----TAHTKAERNI-L-E--E-V-K-HPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLER-E--GIFMEDTACFYLAEISMALGHLH-QKGIIYRDLKPENIMLN-HQG----HVKLTDFGLCKESIH-----H--T-FCGTIEYMAPEILMR-----S---GHNRAVDWWSLGALMYDMLTG-APPF-----T--G---E----NR---KKTIDKILKCK--LNLP----PYLTQEARDLLKKLLKRNAASRLGAG-P-GDA-GE-VQAHPFFRHIN---WEELLARKVEPPFKPLLQSEEDVSQ-DSKFTRQ----T----------SESANQV----FLGFAYVAPS--