@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : ALPK1_HUMAN: (2015-10-03 )
MNNQKVVAVLLQECKQVLDQLLLEAPDVSEEDKSEDQRCRALLPSELRTLIQEAKEMKWPFVPEKWQYKQAVGPEDKTNLKDVIGAGLQQLLASLRASILARDCAAAAAIVFLVDRFLYGLDVSGKLLQVAKGLHKLQPATPIAPQVVIRQARISVNSGKLLKAEYILSSLISNNGATGTWLYRNESDKVLVQSVCIQIRGQILQKLGMWYEAAELIWASIVGYLALPQPDKKGLSTSLGILADIFVSMSKNDYEKFKNNPQINLSLLKEFDHHLLSAAEACKLAAAFSAYTPLFVLTAVNIRGTCLLSYSSSNDCPPELKNLHLCEAKEAFEIGLLTKRDDEPVTGKQELHSFVKAAFGLTTVHRRLHGETGTVHAASQLCKEAMGKLYNFSTSSRSQDREALSQEVMSVIAQVKEHLQVQSFSNVDDRSYVPESFECRLDKLILHGQGDFQKILDTYSQHHTSVCEVFESDCGNNKNEQKDAKTGVCITALKTEIKNIDTVSTTQEKPHCQRDTGISSSLMGKNVQRELRRGGRRNWTHSDAFRVSLDQDVETETEPSDYSNGEGAVFNKSLSGSQTSSAWSNLSGFSSSASWEEVNYHVDDRSARKEPGKEHLVDTQCSTALSEELENDREGRAMHSLHSQLHDLSLQEPNNDNLEPSQNQPQQQMPLTPFSPHNTPGIFLAPGAGLLEGAPEGIQEVRNMGPRNTSAHSRPSYRSASWSSDSGRPKNMGTHPSVQKEEAFEIIVEFPETNCDVKDRQGKEQGEEISERGAGPTFKASPSWVDPEGETAESTEDAPLDFHRVLHNSLGNISMLPCSSFTPNWPVQNPDSRKSGGPVAEQGIDPDASTVDEEGQLLDSMDVPCTNGHGSHRLCILRQPPGQRAETPNSSVSGNILFPVLSEDCTTTEEGNQPGNMLNCSQNSSSSSVWWLKSPAFSSGSSEGDSPWSYLNSSGSSWVSLPGKMRKEILEARTLQPDDFEKLLAGVRHDWLFQRLENTGVFKPSQLHRAHSALLLKYSKKSELWTAQETIVYLGDYLTVKKKGRQRNAFWVHHLHQEEILGRYVGKDYKEQKGLWHHFTDVERQMTAQHYVTEFNKRLYEQNIPTQIFYIPSTILLILEDKTIKGCISVEPYILGEFVKLSNNTKVVKTEYKATEYGLAYGHFSYEFSNHRDVVVDLQGWVTGNGKGLIYLTDPQIHSVDQKVFTTNFGKRGIFYFFNNQHVECNEICHRLSLTRPSMEKPCT
Atome Classification :
(14 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570.......580.......590.......600.......610.......620.......630.......640.......650.......660.......670.......680.......690.......700.......710.......720.......730.......740.......750.......760.......770.......780.......790.......800.......810.......820.......830.......840.......850.......860.......870.......880.......890.......900.......910.......920.......930.......940.......950.......960.......970.......980.......990.......1000......1010......1020......1030......1040......1050......1060......1070.........1080......1090......1100......1110...-...1120...---...1130......1140......1150......1160......1170......1180......1190......1200..-....1210......1220......1230......1240.
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MN
N
Q
K
V
V
A
V
L
L
Q
E
C
K
Q
V
L
D
Q
L
L
LEAPDVSEEDK
S
E
D
Q
R
C
R
A
L
L
P
S
E
L
R
T
L
I
Q
E
A
K
EMKWPFVPEKW
Q
Y
KQAVGPEDKT
N
L
K
D
V
I
G
A
G
L
Q
Q
L
L
A
S
L
R
A
S
I
L
A
R
D
C
A
A
A
A
A
I
V
F
L
V
D
R
F
L
YGLDVS
G
K
L
L
Q
V
A
K
G
L
H
KLQPATPI
A
P
Q
V
V
I
R
Q
A
R
I
SVNSG
K
L
L
K
A
E
Y
I
L
S
S
L
I
SNNGA
T
G
T
W
L
Y
RNES
D
K
V
L
V
Q
S
V
C
I
Q
I
R
G
Q
I
L
Q
K
L
G
M
W
Y
E
A
A
E
L
I
W
A
S
I
V
G
Y
LALPQPDKKG
L
S
T
S
L
G
I
L
A
D
I
F
V
SMSKN
D
Y
E
K
FKNNPQ
I
N
L
S
L
L
K
E
F
D
H
H
L
L
S
A
A
E
A
C
K
L
A
A
A
F
SAYT
P
L
F
V
L
T
A
VNI
R
G
T
C
L
L
S
YSSSNDC
P
P
E
LKNLHLCEA
K
E
A
F
E
I
G
L
L
TKRDDEPVT
G
K
Q
E
L
H
S
F
V
K
A
A
F
G
L
T
T
V
H
R
R
LHGETG
T
V
H
A
A
S
Q
L
C
K
E
A
M
G
K
LYNFSTSSRS
Q
D
R
E
A
L
S
Q
E
V
M
S
V
I
A
Q
V
K
E
H
L
Q
VQSFSNVDDRSYVP
E
S
F
E
C
R
L
D
K
L
I
LHGQG
D
F
Q
K
I
L
D
T
Y
S
Q
H
H
T
S
V
C
E
V
F
E
S
DCGNNKN
E
Q
K
DAKT
G
V
C
I
T
A
L
K
T
E
I
KNIDTVSTTQEKPHCQRDTGI
S
S
S
L
M
G
K
N
V
Q
R
E
L
R
RGGRRNWTHS
D
A
F
R
V
SLDQDVETETEPSDYSNGEG
A
V
F
NKSLSGSQTS
S
A
WSNLSGFSSSASW
E
E
V
N
Y
HVDDRSARKEPGKEHLVD
T
Q
C
S
T
A
L
S
E
E
L
ENDRE
G
R
A
M
H
S
L
H
S
Q
L
H
DLSLQEPNNDNLEPSQNQPQQQMPLTPFSPHNTP
G
I
F
LAPGAGLLEGA
P
E
G
I
Q
E
V
R
NMGPRNTSAHSRPSYRSASWSSDSGRPKNMGTHPSV
Q
K
E
E
A
F
E
I
I
V
EFPETNCDVKDRQGKEQ
G
E
E
I
S
E
RGAGPTFKASPSWVDPEGETAESTEDAP
L
D
F
H
R
V
L
H
NSLGN
I
S
MLPCSSFTPNWPVQNPDSRKSGGPVAEQGIDPDASTVDEEGQ
L
L
DSMDVPCTNGHGS
H
R
L
C
I
L
RQPPGQRAETPNSSVSG
N
I
L
F
P
VLSEDCTTTEEGNQPG
N
M
L
NCSQNSSSS
S
V
W
W
LKSPAFSSGSSEGDS
P
W
S
Y
LNSSGSSWVSL
P
G
K
M
R
K
E
I
L
E
ARTLQ
P
D
D
F
E
K
L
L
A
G
V
R
H
D
W
L
F
Q
R
L
E
NTGVF
K
P
S
Q
L
H
R
A
H
S
A
L
L
L
K
YSKKSELWTAQ
E
T
I
V
Y
LG
D
Y
L
T
V
KKKGRQRN
A
F
W
V
H
HL
H
Q
E
E
I
L
G
R
Y
VGK
D
Y
K
---
E
QKGL
W
H
H
F
T
D
V
E
R
Q
M
T
A
Q
H
Y
V
T
E
F
N
K
R
L
Y
EQNIP
T
Q
I
F
Y
IP
S
T
I
L
-
L
I
L
EDKTI
K
G
---
C
ISV
E
P
Y
I
L
G
E
F
V
KLSNN
T
K
V
V
K
T
EYKATEYG
L
A
Y
G
H
F
S
Y
EFSNH
R
D
V
V
V
D
L
Q
G
W
V
TGNG
K
G
L
I
Y
LTDPQIHSV
D
Q
K
V
F-TTNFGK
R
G
I
F
Y
F
FNNQHV
E
C
N
E
I
C
H
R
LSLTRPSMEKPCT
8
PsiBlast_PDB
75.25
33%
-16
- C3 -
3LMI
1
MHCKA_DICDI
A:
[107-271]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
F
V
L
K
L
Y
K
K---
Q
A
S
R
E
L
Y
F
E
D
V
K
M
Q
M
V
C
R
D
W
G
N
K
F
N
Q
K
----
K
P
P
K
K
I
E
F
L
M
S
W
V
V
E
L
I
D
R
S
P
S
-
N
G
Q
P
I
L
C
S
I
E
P
L
L
V
G
E
F
K
K
N
N
S
N
Y
G
A
V
L
T
N
R
S
T
P
Q
---
A
F
S
H
F
T
Y
E
L
S
N
K
Q
M
I
V
V
D
I
Q
G
V
D
D
------
L
Y
-
T
A
P
Q
I
H
T
P
D
G
K
G
F
G
L
G
N
L
G
K
A
G
I
N
K
F
I
T
T
H
--
K
C
N
A
V
C
A
L
L
D
L
D
V
K
-------
18
PsiBlast_CBE
73.05
33%
-15
- C3 -
3LMI
1
MHCKA_DICDI
C:
[107-271]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
F
V
L
K
L
Y
K
K--
Q
Q
A
S
R
E
L
Y
F
E
D
V
K
M
Q
M
V
C
R
D
W
G
N
K
F
N
Q
K
----
K
P
P
K
K
I
E
F
L
M
S
W
V
V
E
L
I
D
R
S
P
S
-
N
G
QPI
L
C
S
I
E
P
L
L
V
G
E
F
K
K
N
N
S
N
Y
G
A
V
L
T
N
R
S
T
P
Q
---
A
F
S
H
F
T
Y
E
L
S
N
K
Q
M
I
V
V
D
I
Q
G
V
D
D
------
L
Y
-
T
A
P
Q
I
H
T
P
D
G
K
G
F
G
L
G
N
L
G
K
A
G
I
N
K
F
I
T
T
H
--
K
C
N
A
V
C
A
L
L
D
L
D
V
K
-------
17
PsiBlast_CBE
72.52
33%
-19
- C3 -
3LMI
1
D:
[107-271]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
F
V
L
K
L
Y
K
KE----
S
R
E
L
Y
F
E
D
V
K
M
Q
M
V
C
R
D
W
G
N
K
F
N
Q
K
----
K
P
P
K
K
I
E
F
L
M
S
W
V
V
E
L
I
D
R
S
P
S
S
N
G
QPI
L
C
S
I
E
P
L
L
V
G
E
F
K
K
N
N
S
N
Y
G
A
V
L
T
N
R
S
T
P
Q
---
A
F
S
H
F
T
Y
E
L
S
N
K
Q
M
I
V
V
D
I
Q
G
V
D
D
------
L
Y
-
T
A
P
Q
I
H
T
P
D
G
K
G
F
G
L
G
N
L
G
K
A
G
I
N
K
F
I
T
T
H
--
K
C
N
A
V
C
A
L
L
D
L
D
V
K
L
------
7
PsiBlast_PDB
72.19
33%
-22
- C3 -
4ZMF
1
?
A:
[107-271]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
F
V
L
K
L
Y
K
KEA---
S
R
E
L
Y
F
E
D
V
K
M
Q
M
V
C
R
D
W
G
N
K
F
N
Q
K
----
K
P
P
K
K
I
E
F
L
M
S
W
V
V
E
L
I
D
R
S
P
S
S
N
G
Q
P
I
L
C
S
I
E
P
L
L
V
G
E
F
K
K
N
N
S
N
Y
G
A
V
L
T
N
R
S
T
P
Q
---
A
F
S
H
F
T
Y
E
L
S
N
K
Q
M
I
V
V
D
I
Q
G
V
D
D
------
L
Y
-
T
-
P
Q
I
H
T
P
D
G
K
G
F
G
L
G
N
L
G
K
A
G
I
N
K
F
I
T
T
H
--
K
C
N
A
V
C
A
L
L
D
L
D
V
K
-------
3
PsiBlast_PDB
71.04
33%
-17
- C3 -
3PDT
1
A:
[107-271]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
F
V
L
K
L
Y
K
KE-
Q
Q
A
S
R
E
L
Y
F
E
D
V
K
M
Q
M
V
C
R
D
W
G
N
K
F
N
Q
K
----
K
P
P
K
K
I
E
F
L
M
S
W
V
V
E
L
I
D
R
S
P
S
S
N
G
Q
P
I
L
C
S
I
E
P
L
L
V
G
E
F
K
K
N
N
S
N
Y
G
A
V
L
T
N
R
S
T
P
Q
---
A
F
S
H
F
T
Y
E
L
S
N
K
Q
M
I
V
V
D
I
Q
G
V
D
D
-------
L
Y
T
D
P
Q
I
H
T
P
D
G
K
G
F
G
L
G
N
L
G
K
A
G
I
N
K
F
I
T
T
H
--
K
C
N
A
V
C
A
L
L
D
L
D
V
K
L
------
6
PsiBlast_PDB
70.81
33%
-18
- C3 -
4ZME
1
?
A:
[107-271]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
F
V
L
K
L
Y
K
K--
Q
Q
A
S
R
E
L
Y
F
E
D
V
K
M
Q
M
V
C
R
D
W
G
N
K
F
N
Q
K
----
K
P
P
K
K
I
E
F
L
M
S
W
V
V
E
L
I
D
R
S
P
S
S
N
G
Q
P
I
L
C
S
I
E
P
L
L
V
G
E
F
K
K
N
N
S
N
Y
G
A
V
L
T
N
R
S
T
P
Q
---
A
F
S
H
F
T
Y
E
L
S
N
K
Q
M
I
V
V
D
I
Q
G
V
D
D
------
L
Y
-
T
-
P
Q
I
H
T
P
D
G
K
G
F
G
L
G
N
L
G
K
A
G
I
N
K
F
I
T
T
H
--
K
C
N
A
V
C
A
L
L
D
L
D
V
K
L
G
G
V
L
S
G
2
PsiBlast_PDB
70.61
33%
-17
- C3 -
3LLA
1
MHCKA_DICDI
A:
[107-271]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
F
V
L
K
L
Y
K
KE-
Q
Q
A
S
R
E
L
Y
F
E
D
V
K
M
Q
M
V
C
R
D
W
G
N
K
F
N
Q
K
----
K
P
P
K
K
I
E
F
L
M
S
W
V
V
E
L
I
D
R
S
P
S
S
N
G
Q
P
I
L
C
S
I
E
P
L
L
V
G
E
F
K
K
N
N
S
N
Y
G
A
V
L
T
N
R
S
T
P
Q
---
A
F
S
H
F
T
Y
E
L
S
N
K
Q
M
I
V
V
D
I
Q
G
V
D
D
------
L
Y
-
T
D
P
Q
I
H
T
P
D
G
K
G
F
G
L
G
N
L
G
K
A
G
I
N
K
F
I
T
T
H
--
K
C
N
A
V
C
A
L
L
D
L
D
V
K
L
------
19
PsiBlast_CBE
70.50
33%
-17
- C3 -
3LMI
1
MHCKA_DICDI
B:
[107-271]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
F
V
L
K
L
Y
K
K--
Q
Q
A
S
R
E
L
Y
F
E
D
V
K
M
Q
M
V
C
R
D
W
G
N
K
F
N
Q
K
----
K
P
P
K
K
I
E
F
L
M
S
W
V
V
E
L
I
D
R
S
P
S
S
N
G
Q
P
I
L
C
S
I
E
P
L
L
V
G
E
F
K
K
N
N
S
N
Y
G
A
V
L
T
N
R
S
T
P
Q
---
A
F
S
H
F
T
Y
E
L
S
N
K
Q
M
I
V
V
D
I
Q
G
V
D
D
------
L
Y
-
T
A
P
Q
I
H
T
P
D
G
K
G
F
G
L
G
N
L
G
K
A
G
I
N
K
F
I
T
T
H
--
K
C
N
A
V
C
A
L
L
D
L
D
V
K
L
------
15
PsiBlast_CBE
70.22
32%
-10
- C3 -
4ZME
2
?
B:
[107-271]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
F
V
L
K
L
Y
K
K----
A
S
R
E
L
Y
F
E
D
V
K
M
Q
M
V
C
R
D
W
G
N
K
F
N
Q
K
----
K
P
P
K
K
I
E
F
L
M
S
W
V
V
E
L
I
D
R
S
P
S
S
N
G
Q
P
I
L
C
S
I
E
P
L
L
V
G
E
F
K
K
N
N
S
N
Y
G
A
V
L
T
N
R
S
T
P
Q
---
A
F
S
H
F
T
Y
E
L
S
N
K
Q
M
I
V
V
D
I
Q
--------
G
V
D
D
L
Y
T
P
Q
I
H
T
P
D
G
K
G
F
G
L
G
N
L
G
K
A
G
I
N
K
F
I
T
T
H
--
K
C
N
A
V
C
A
L
L
D
L
D
V
K
L
G
-----
14
PsiBlast_CBE
70.07
32%
-10
- C3 -
4ZMF
1
?
B:
[107-271]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
F
V
L
K
L
Y
K
KEA--
A
S
R
E
L
Y
F
E
D
V
K
M
Q
M
V
C
R
D
W
G
N
K
F
N
Q
K
----
K
P
P
K
K
I
E
F
L
M
S
W
V
V
E
L
I
D
R
S
P
--
N
G
Q
P
I
L
C
S
I
E
P
L
L
V
G
E
F
K
K
N
N
S
N
Y
G
A
V
L
T
N
R
S
T
P
Q
---
A
F
S
H
F
T
Y
E
L
S
N
K
Q
M
I
V
V
D
I
Q
--------
G
V
D
D
L
Y
T
P
Q
I
H
T
P
D
G
K
G
F
G
L
G
N
L
G
K
A
G
I
N
K
F
I
T
T
H
--
K
C
N
A
V
C
A
L
L
D
L
D
V
K
-------
13
PsiBlast_CBE
70.06
33%
-16
- C3 -
3LLA
1
B:
[107-271]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
F
V
L
K
L
Y
K
KE-
Q
Q
A
S
R
E
L
Y
F
E
D
V
K
M
Q
M
V
C
R
D
W
G
N
K
F
N
Q
K
----
K
P
P
K
K
I
E
F
L
M
S
W
V
V
E
L
I
D
R
S
P
S
-
N
G
Q
P
I
L
C
S
I
E
P
L
L
V
G
E
F
K
K
N
N
S
N
Y
G
A
V
L
T
N
R
S
T
P
Q
---
A
F
S
H
F
T
Y
E
L
S
N
K
Q
M
I
V
V
D
I
Q
G
V
D
D
------
L
Y
-
T
D
P
Q
I
H
T
P
D
G
K
G
F
G
L
G
N
L
G
K
A
G
I
N
K
F
I
T
T
H
--
K
C
N
A
V
C
A
L
L
D
L
D
V
K
L
G
G
----
1
PsiBlast_PDB
70.05
33%
-14
- C3 -
3LKM
1
A:
[107-271]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
F
V
L
K
L
Y
K
KE-
Q
Q
A
S
R
E
L
Y
F
E
D
V
K
M
Q
M
V
C
R
D
W
G
N
K
F
N
Q
K
----
K
P
P
K
K
I
E
F
L
M
S
W
V
V
E
L
I
D
R
S
P
S
S
N
G
Q
P
I
L
C
S
I
E
P
L
L
V
G
E
F
K
K
N
N
S
N
Y
G
A
V
L
T
N
R
S
T
P
Q
---
A
F
S
H
F
T
Y
E
L
S
N
K
Q
M
I
V
V
D
I
Q
G
V
D
D
------
L
Y
-
T
D
P
Q
I
H
T
P
D
G
K
G
F
G
L
G
N
L
G
K
A
G
I
N
K
F
I
T
T
H
--
K
C
N
A
V
C
A
L
L
D
L
D
V
--------
9
PsiBlast_PDB
69.99
33%
-17
- C3 -
4ZS4
1
?
A:
[107-271]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
F
V
L
K
L
Y
K
KE-
Q
Q
A
S
R
E
L
Y
F
E
D
V
K
M
Q
M
V
C
R
D
W
G
N
K
F
N
Q
K
----
K
P
P
K
K
I
E
F
L
M
S
W
V
V
E
L
I
D
R
S
P
S
S
N
G
Q
P
I
L
C
S
I
E
P
L
L
V
G
E
F
K
K
N
N
S
N
Y
G
A
V
L
T
N
R
S
T
P
Q
---
A
F
S
H
F
T
Y
E
L
S
N
K
Q
M
I
V
V
A
I
Q
G
V
D
D
------
L
Y
-
T
D
P
Q
I
H
T
P
D
G
K
G
F
G
L
G
N
L
G
K
A
G
I
N
K
F
I
T
T
H
--
K
C
N
A
V
C
A
L
L
D
L
D
V
--------
16
PsiBlast_CBE
69.83
33%
-19
* C3 *
4ZS4
1
?
B:
[107-271]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
F
V
L
K
L
Y
K
KE-
Q
Q
A
S
R
E
L
Y
F
E
D
V
K
M
Q
M
V
C
R
D
W
G
N
K
F
N
Q
K
----
K
P
P
K
K
I
E
F
L
M
S
W
V
V
E
L
I
D
R
S
P
S
S
N
G
Q
P
I
L
C
S
I
E
P
L
L
V
G
E
F
K
K
N
N
S
N
Y
G
A
V
L
T
N
R
S
T
P
Q
---
A
F
S
H
F
T
Y
E
L
S
N
K
Q
M
I
V
V
A
I
Q
G
V
D
D
------
L
Y
-
T
D
P
Q
I
H
T
P
D
G
K
G
F
G
L
G
N
L
G
K
A
G
I
N
K
F
I
T
T
H
--
K
C
N
A
V
C
A
L
L
D
L
D
V
K
L
G
-----