@TOME V2.3
(Nov 2016)

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Alignment:

3D Common Core:

Structural Clustering:

Modeller Result :

Complexes Modeling
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Sequence & Result Tab:

Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : ARBK1_HUMAN: (2015-10-03 )
MADLEAVLADVSYLMAMEKSKATPAARASKKILLPEPSIRSVMQKYLEDRGEVTFEKIFSQKLGYLLFRDFCLNHLEEARPLVEFYEEIKKYEKLETEEERVARSREIFDSYIMKELLACSHPFSKSATEHVQGHLGKKQVPPDLFQPYIEEICQNLRGDVFQKFIESDKFTRFCQWKNVELNIHLTMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLHYHLSQHGVFSEADMRFYAAEIILGLEHMHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKKPHASVGTHGYMAPEVLQKGVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTMAVELPDSFSPELRSLLEGLLQRDVNRRLGCLGRGAQEVKESPFFRSLDWQMVFLQKYPPPLIPPRGEVNAADAFDIGSFDEEDTKGIKLLDSDQELYRNFPLTISERWQQEVAETVFDTINAETDRLEARKKAKNKQLGHEEDYALGKDCIMHGYMSKMGNPFLTQWQRRYFYLFPNRLEWRGEGEAPQSLLTMEEIQSVEETQIKERKCLLLKIRGGKQFILQCDSDPELVQWKKELRDAYREAQQLVQRVPKMKNKPRSPVVELSKVPLVQRGSANGL

Atome Classification :

(67 SA) .........10........20..--......---30--.----........40.--.......50.......-.-60........70........80----.----.......90........100......---.110.....-..-120.......130-.......140..--.....150.......160.......170.......180.......190.......200.......210-.---.---.......220.....-..230.-.....-.240.......250.......260.......270.......280-...----....----.--.290.......300.......310........320.......330.......340.--.---.--.-.-.-.-.350-........360........370.......380.......390.....-.--.-400........410.......420.......430.......440-........450.......460.......470.......480.......490..-.....---------500-------........510-........520..-.-....530.......540.......550.......560.......570.......580.......590.......600.......610.......620.......630.......640.......650.......660.......670.......680.......
(Atome) (Ident) (Tito) (Num) (Ligand) (Uniprot) MADLEAVLADVSYLMAMEKSKAT--PAARAS---K---K----ILLPEPSIRSV--MQKYLEDRGEVTFEKI-F-SQKLGYLLFRDFCLNHLEEARP----L----VEFYEEIKKYEKLETEEERVARSREI---FDSYIMKEL-LA-CSHPFSKSATEHV-QGHLGKKQVPPD--LFQPYIEEICQNLRGDVFQKFIESDKFTRFCQWKNVELNIHLTMNDFSVHRIIGRGGFGEVYGCRK---A---D---TGKMYAMKCLDKKRI-KMKQGE-TLALN-ERIMLSLVSTGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLH---YHL----SQHG----V--FSEADMRFYAAEIILGLEHMHN-RFVVYRDLKPANILLDEHGHVRISDLGLACD-F--S---K--K-K-P-H-ASV--GTHGYMAPE-VLQKGVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTK-D--K-H-EIDRMTLTMAVELPDSFSPELRSLLEGLLQRDVNRRLGCL-G-RGAQEVKESPFFRSLDWQMVFLQKYPPPLIPPRGEVNAADAFDIGSFDEEDTK-GIKLL---------DS--------DQELYRNFP-L-TISERWQQEVAET-V-FDTINAETDRLEARKKAKNKQLGHEEDYALGKDCIMHGYMSKMGNPFLTQWQRRYFYLFPNRLEWRGEGEAPQSLLTMEEIQSVEETQIKERKCLLLKIRGGKQFILQCDSDPELVQWKKELRDAYREAQQLVQRVPKMKNKPRSPVVELSKVPLVQRGSANGL
3 PsiBlast_PDB 98.25100%-108 - C1 -3KRW ARBK1_HUMAN A:[29-670] ----------------------------------K---K----ILLPEPSIRSV--MQKYLEDRGEVTFEKI-F-SQKLGYLLFRDFCLNHLEEARP----L----VEFYEEIKKYEKLETEEERVARSREI---FDSYIMKEL-LA---HPFSKSATEHV-QGHLGKKQVPPD--LFQPYIEEICQNLRGDVFQKFIESDKFTRFCQWKNVELNIHLTMNDFSVHRIIGRGGFGEVYGCRK---A---D---TGKMYAMKCLDKKRI-KMKQGE-TLALN-ERIMLSLVSTGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLH---YHL----SQHG----V--FSEADMRFYAAEIILGLEHMHN-RFVVYRDLKPANILLDEHGHVRISDLGLACD-F--S---K--K-K-P-H-ASV--GTHGYMAPE-VLQKGVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTK-D--K-H-EIDRMTLTMAVELPDSFSPELRSLLEGLLQRDVNRRLGCL-G-RGAQEVKESPFFRSLDWQMVFLQKYPPPLIPPR---------------EEDTK-GIKLL---------DS--------DQELYRNFP-L-TISERWQQEVAET-V-FDTINAETDRLEARKKAKNKQLGHEEDYALGKDCIMHGYMSKM-------WQRRYFYLFPNRLEWRGEGEAPQSLLTMEEIQSVEETQIKERKCLLLKIRGGKQFILQCDSDPELVQWKKELRDAYREAQQLVQRVPKMKNKPRSP------------------
4 PsiBlast_PDB 98.03100%-106 - C1 -3KRX ARBK1_HUMAN A:[29-670] ----------------------------------K---K----ILLPEPSIRSV--MQKYLEDRGEVTFEKI-F-SQKLGYLLFRDFCLNHLEEARP----L----VEFYEEIKKYEKLETEEERVARSREI---FDSYIMKEL-LA---HPFSKSATEHV-QGHLGKKQVPPD--LFQPYIEEICQNLRGDVFQKFIESDKFTRFCQWKNVELNIHLTMNDFSVHRIIGRGGFGEVYGCRK---A---D---TGKMYAMKCLDKKRI-KMKQGE-TLALN-ERIMLSLVSTGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLH---YHL----SQHG----V--FSEADMRFYAAEIILGLEHMHN-RFVVYRDLKPANILLDEHGHVRISDLGLACD-F--S---K--K-K-P-H-ASV--GTHGYMAPE-VLQKGVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTK-D--K-H-EIDRMTLTMAVELPDSFSPELRSLLEGLLQRDVNRRLGCL-G-RGAQEVKESPFFRSLDWQMVFLQKYPPPLIPPR---------------EEDTK-GIKLL---------DS--------DQELYRNFP-L-TISERWQQEVAET-V-FDTINAETDRLEARKKAKNKQLGHEEDYALGKDCIMHGYMSKM-------WQRRYFYLFPNRLEWRGEGEAPQSLLTMEEIQSVEETQIKERKCLLLKIRGGKQFILQCDSDPELVQWKKELRDAYREAQQLVQRVPKMKNKPRSP------------------
13 PsiBlast_PDB 97.57100%-107 - C1 -4MK0 ARBK1_HUMAN A:[1-639] ----------------------------------K---K----ILLPEPSIRSV--MQKYLEDRGEVTFEKI-F-SQKLGYLLFRDFCLNHLEEARP----L----VEFYEEIKKYEKLETEEERVARSREI---FDSYIMKEL-LA-CSHPFSKSATEHV-QGHLGKKQVPPD--LFQPYIEEICQNLRGDVFQKFIESDKFTRFCQWKNVELNIHLTMNDFSVHRIIGRGGFGEVYGCRK---A---D---TGKMYAMKCLDKKRI-KMKQGE-TLALN-ERIMLSLVSTGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLH---YHL----SQHG----V--FSEADMRFYAAEIILGLEHMHN-RFVVYRDLKPANILLDEHGHVRISDLGLACD-F--S---K--K-K-P-H-ASV--GTHGYMAPE-VLQKGVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTK-D--K-H-EIDRMTLTMAVELPDSFSPELRSLLEGLLQRDVNRRLGCL-G-RGAQEVKESPFFRSLDWQMVFLQKYPPPLIPPRGEVNAADAF---------TK-GIKLL---------DS--------DQELYRNFP-L-TISERWQQEVAET-V-FDTINAETDRLEARKKAKNKQLGHEEDYALGKDCIMHGYMSKMGNPFLTQWQRRYFYLFPNRLEWRGEGEAPQSLLTMEEIQSVEETQIKERKCLLLKIRGGKQFILQCDSDPELVQWKKELRDAYREAQQLVQRVPKMKNKPA--------------------
11 PsiBlast_PDB 97.4298%-111 - C1 -3PVU ARBK1_BOVIN A:[30-668] ----------------------------------K---K----ILLPEPSIRSV--MQKYLEDRGEVTFEKI-F-SQKLGYLLFRDFCLKHLEEAKP----L----VEFYEEIKKYEKLETEEERLVCSREI---FDTYIMKEL-LA-CSHPFSKSAIEHV-QGHLVKKQVPPD--LFQPYIEEICQNLRGDVFQKFIESDKFTRFCQWKNVELNIHLTMNDFSVHRIIGRGGFGEVYGCRK---A---D---TGKMYAMKCLDKKRI-KMKQGE-TLALN-ERIMLSLVSTGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLH---YHL----SQHG----V--FSEADMRFYAAEIILGLEHMHN-RFVVYRDLKPANILLDEHGHVRISDLGLACD-F--S---K--K-K-P-H-ASV--GTHGYMAPE-VLQKGVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTK-D--K-H-EIDRMTLTMAVELPDSFSPELRSLLEGLLQRDVNRRLGCL-G-RGAQEVKESPFFRSLDWQMVFLQKYPPPLIPPRG----------------------------------DS--------DQELYRNFP-L-TISERWQQEVAET-V-FDTINAETDRLEARKKTKNKQLGHEEDYALGKDCIMHGYMSKMG------WQRRYFYLFPNRLEWRGEGEAPQSLLTMEEIQSVEETQIKERKCLLLKIRGGKQFVLQCDSDPELVQWKKELRDAYREAQQLVQRVPKMKNKP---------------------
12 PsiBlast_PDB 96.9498%-109 - C1 -3PVW ARBK1_BOVIN A:[29-668] ------------------------------S---K---K----ILLPEPSIRSV--MQKYLEDRGEVTFEKI-F-SQKLGYLLFRDFCLKHLEEAKP----L----VEFYEEIKKYEKLETEEERLVCSREI---FDTYIMKEL-LA-CSHPFSKSAIEHV-QGHLVKKQVPPD--LFQPYIEEICQNLRGDVFQKFIESDKFTRFCQWKNVELNIHLTMNDFSVHRIIGRGGFGEVYGCRK---A---D---TGKMYAMKCLDKKRI-KMKQGE-TLALN-ERIMLSLVSTGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLH---YHL----SQHG----V--FSEADMRFYAAEIILGLEHMHN-RFVVYRDLKPANILLDEHGHVRISDLGLACD-F--S---K--K-K-P-H-ASV--GTHGYMAPE-VLQKGVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTK-D--K-H-EIDRMTLTMAVELPDSFSPELRSLLEGLLQRDVNRRLGCL-G-RGAQEVKESPFFRSLDWQMVFLQKYPPPLIPPRG----------------------KLL---------DS--------DQELYRNFP-L-TISERWQQEVAET-V-FDTINAETDRLEARKKTKNKQLGHEEDYALGKDCIMHGYMSKMG------WQRRYFYLFPNRLEWRGEGEAPQSLLTMEEIQSVEETQIKERKCLLLKIRGGKQFVLQCDSDPELVQWKKELRDAYREAQQLVQRVPKMKNKP---------------------
2 PsiBlast_PDB 96.89100%-107 - C1 -4PNK ARBK1_HUMAN A:[30-668] ----------------------------------K---K----ILLPEPSIRSV--MQKYLEDRGEVTFEKI-F-SQKLGYLLFRDFCLNHLEEARP----L----VEFYEEIKKYEKLETEEERVARSREI---FDSYIMKEL-LA-CSHPFSKSATEHV-QGHLGKKQVPPD--LFQPYIEEICQNLRGDVFQKFIESDKFTRFCQWKNVELNIHLTMNDFSVHRIIGRGGFGEVYGCRK---A---D---TGKMYAMKCLDKKRI-KMKQGE-TLALN-ERIMLSLVSTGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLH---YHL----SQHG----V--FSEADMRFYAAEIILGLEHMHN-RFVVYRDLKPANILLDEHGHVRISDLGLACD-F--S---K--K-K-P-H-ASV--GTHGYMAPE-VLQKGVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTK-D--K-H-EIDRMTLTMAVELPDSFSPELRSLLEGLLQRDVNRRLGCL-G-RGAQEVKESPFFRSLDWQMVFLQKYPPPLIPPR-EVNA-------------TK-GIKLL---------DS--------DQELYRNFP-L-TISERWQQEVAET-V-FDTINAETDRLEARKKAKNKQLGHEEDYALGKDCIMHGYMSKMGNPFLTQWQRRYFYLFPNRLEWRGEGEAPQSLLTMEEIQSVEETQIKERKCLLLKIRGGKQFILQCDSDPELVQWKKELRDAYREAQQLVQRVPKMKNKP---------------------
85 Fugue 65.7938% -90 - C1 -2ACX GRK6_HUMAN A:[14-532] ------------------KARKG--KSKKWR---Q---M----LQFPHISQCEE--LRLSLERDYHSLCER-----NPIGRLLFREFCATR-PELSR----C----VAFLDGVAEYE-VTPDDKRKACGRNL---TQNFLSHTG-PD-LIPEVPRQLVTNC-TQRLEQGPCK-D--LFQELTRLTHEYLSVAPFADYLDSIYFNRFLQWKWLERQ-PVTKNTFRQYRVLGKGGFGEVCACQV---R---A---TGKMYACKKLEKKRI-KKRKGE-AMALN-EKQILEKVNS---RFVVSLAYAYETKDALCLVLTLMNGGDLK---FHI----YHMGQA--G--FPEARAVFYAAEICCGLEDLHR-ERIVYRDLKPENILLDDHGHIRISDLGLAVH-V--P---E--G-Q-T-IKGRV--GTVGYMAPE-VV-KNERYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIK--R-E-EVERLVKEVPEEYSERFSPQARSLCSQLLCKDPAERLGCR-G-GSAREVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYCE-----------------------------PT--------DQDFYQKFATG-SVPIPWQNEMVET-----------------------------------------------------------ECFQELNVFGLDGS----------------------------------------------------------------------------------------------
37 PsiBlast_CBE 65.3434% -93 - C1 -3C4W RK_BOVIN B:[9-529] ------VVANSAFIAARGSFDASSGPASRDR---KYLAR----LKLPPLSKCEA--LRESLD----LGFEGMCL-EQPIGKRLFQQFLRTH-EQHGP----A----LQLWKDIEDYDTAD-DALRPQKAQAL---RAAYLEPQAQLF-CSFLDAETVARAR-A--------GDG--LFQPLLRAVLAHLGQAPFQEFLDSLYFLRFLQWKWLEAQ-PMGEDWFLDFRVLGRGGFGEVFACQM---K---A---TGKLYACKKLNKKRL-KKRKGY-QGAMV-EKKILAKVHS---RFIVSLAYAFETKTDLCLVMTIMNGGDIR---YHIYNVDEDNP----G--FQEPRAIFYTAQIVSGLEHLHQ-RNIIYRDLKPENVLLDDDGNVRISDLGLAVE-LKAG---Q--T-K-T-K-GYA--GTPGFMAPE-LLL-GEEYDFSVDYFALGVTLYEMIAARGPFRARGEKVE--N-K-ELKQRVLEQAVTYPDKFSPASKDFCEALLQKDPEKRLGFR-D-GSCDGLRTHPLFRDISWRQLEAGMLTPPFVPDSRTVYAKN--------T--VK-GVAFE---------KA--------DTEFFQEFA-SGTCPIPWQEEMIETGV-FGDLNVWRP-----------------------------------------------------------------------------------------------------------------------------------------------------------
38 PsiBlast_CBE 64.8934% -97 - C1 -3C4W RK_BOVIN A:[31-529] ----------------------------RDR---KYLAR----LKLPPLSKCEA--LRESLD----LGFEGMCL-EQPIGKRLFQQFLRTH-EQHGP----A----LQLWKDIEDYDTAD-DALRPQKAQAL---RAAYLEPQAQLF-CSFLDAETVARAR-AG------AGDG--LFQPLLRAVLAHLGQAPFQEFLDSLYFLRFLQWKWLEAQ-PMGEDWFLDFRVLGRGGFGEVFACQM---K---A---TGKLYACKKLNKKRL-KKRKGY-QGAMV-EKKILAKVHS---RFIVSLAYAFETKTDLCLVMTIMNGGDIR---YHIYNVDEDNP----G--FQEPRAIFYTAQIVSGLEHLHQ-RNIIYRDLKPENVLLDDDGNVRISDLGLAVE-LKAG---Q--T-K-T-K-GYA--GTPGFMAPE-LLL-GEEYDFSVDYFALGVTLYEMIAARGPFRARGEKVE--N-K-ELKQRVLEQAVTYPDKFSPASKDFCEALLQKDPEKRLGFR-D-GSCDGLRTHPLFRDISWRQLEAGMLTPPFVPD---------QDVGAFST--VK-GVAFE---------KA--------DTEFFQEFA-SGTCPIPWQEEMIETGV-FGDLNVWRP-----------------------------------------------------------------------------------------------------------------------------------------------------------
27 PsiBlast_CBE 64.8934% -97 - C1 -3C4Z RK_BOVIN A:[31-529] ----------------------------RDR---KYLAR----LKLPPLSKCEA--LRESLD----LGFEGMCL-EQPIGKRLFQQFLRTH-EQHGP----A----LQLWKDIEDYDTAD-DALRPQKAQAL---RAAYLEPQAQLF-CSFLDAETVARAR-AG---------G--LFQPLLRAVLAHLGQAPFQEFLDSLYFLRFLQWKWLEAQ-PMGEDWFLDFRVLGRGGFGEVFACQM---K---A---TGKLYACKKLNKKRL-KKRKGY-QGAMV-EKKILAKVHS---RFIVSLAYAFETKTDLCLVMTIMNGGDIR---YHIYNVDEDNP----G--FQEPRAIFYTAQIVSGLEHLHQ-RNIIYRDLKPENVLLDDDGNVRISDLGLAVE-LKAG---Q--T-K-T-K-GYA--GTPGFMAPE-LLL-GEEYDFSVDYFALGVTLYEMIAARGPFRARGEKVE--N-K-ELKQRVLEQAVTYPDKFSPASKDFCEALLQKDPEKRLGFR-D-GSCDGLRTHPLFRDISWRQLEAGMLTPPFVPDSRTVYAKN----GAFS------GVAFE---------KA--------DTEFFQEFA-SGTCPIPWQEEMIETGV-FGDLNVWRP-----------------------------------------------------------------------------------------------------------------------------------------------------------
26 PsiBlast_CBE 64.3634% -93 - C1 -3C50 RK_BOVIN B:[30-529] ---------------------------SRDR---KYLAR----LKLPPLSKCEA--LRESLD----LGFEGMCL-EQPIGKRLFQQFLRTH-EQHGP----A----LQLWKDIEDYDTAD-DALRPQKAQAL---RAAYLEPQAQLF-CSFLDAETVARAR-AG------AGDG--LFQPLLRAVLAHLGQAPFQEFLDSLYFLRFLQWKWLEAQ-PMGEDWFLDFRVLGRGGFGEVFACQM---K---A---TGKLYACKKLNKKRL-KKRKGY-QGAMV-EKKILAKVHS---RFIVSLAYAFETKTDLCLVMTIMNGGDIR---YHIYNVDEDNP----G--FQEPRAIFYTAQIVSGLEHLHQ-RNIIYRDLKPENVLLDDDGNVRISDLGLAVE-LKAG---Q--T-K-T-K-GYA--GTPGFMAPE-LLL-GEEYDFSVDYFALGVTLYEMIAARGPFRARGEKVE--N-K-ELKQRVLEQAVTYPDKFSPASKDFCEALLQKDPEKRLGFR-D-GSCDGLRTHPLFRDISWRQLEAGMLTPPFVPDSRTVYA--------FST--VK-GVAFE---------KA--------DTEFFQEFA-SGTCPIPWQEEMIETGV-FGDLNVWRP-----------------------------------------------------------------------------------------------------------------------------------------------------------
14 PsiBlast_PDB 64.3638%-100 - C1 -4WNK GRK5_BOVIN A:[60-526] ----------------------------------------------------------------------------QPVGRLLFRQFC-----ETRPGLESY----IQFLDSVAEYE-VTPDEKLGEKGKEI---MTKYLTPKS-PV-FITQVGRDLVSQT-EEKLLQKPCK-E--LFSACVQSVHDYLRGEPFHEYLDSMYFDRFLQWKWLERQ-PVTKNTFRQYRVLGKGGFGEVCACQV---R---A---TGKMYACKRLEKKRI-KKRKGE-SMALN-EKQILEKVNSR---FVVNLAYAYETKDALCLVLTIMNGGDLK---FHI----YNMG----NPGFEEERALFYAAEILCGLEDLHH-ENIVYRDLKPENILLDDYGHIRISDLGLAVK-I--P---E--G-DLI-R-GRV--GTVGYMAPE-VLNNQ-RYGLSPDYWGLGCLIYEMIEGQSPFRGRKEK-V--KRE-EVDRRVLETEEVYSHKFSEEAKSICKMLLTKDAKQRLGCQ-E-EGAAEVKRHPFFRNMNFKRLEAGMLDPPFVPDPRAVY-------------------------------HT--------DDDFYSKFS-TGSVPIPWQSEMIETEC-FKELNVFGPHGTLSPDLNRSH-----------------------------------------------------------------------------------------------------------------------------------------------
28 PsiBlast_CBE 64.3334% -98 - C1 -3C4X RK_BOVIN B:[31-529] ----------------------------RDR---KYLAR----LKLPPLSKCEA--LRESLD----LGFEGMCL-EQPIGKRLFQQFLRTH-EQHGP----A----LQLWKDIEDYDTAD-DALRPQKAQAL---RAAYLEPQAQLF-CSFLDAETVARA-----------------FQPLLRAVLAHLGQAPFQEFLDSLYFLRFLQWKWLEAQ-PMGEDWFLDFRVLGRGGFGEVFACQM---K---A---TGKLYACKKLNKKRL-KKRKGY-QGAMV-EKKILAKVHS---RFIVSLAYAFETKTDLCLVMTIMNGGDIR---YHIYNVDEDNP----G--FQEPRAIFYTAQIVSGLEHLHQ-RNIIYRDLKPENVLLDDDGNVRISDLGLAVE-LKAG---Q--T-K-T-K-GYA--GTPGFMAPE-LLL-GEEYDFSVDYFALGVTLYEMIAARGPFRARGEKVE--N-K-ELKQRVLEQAVTYPDKFSPASKDFCEALLQKDPEKRLGFR-D-GSCDGLRTHPLFRDISWRQLEAGMLTPPFVPDSRT-----------------------E---------KA--------DTEFFQEFA-SGTCPIPWQEEMIETGV-FGDLNVWRP-----------------------------------------------------------------------------------------------------------------------------------------------------------
96 HHSearch 64.3035% -93 - C1 -3C4Z RK_BOVIN A:[31-533] ----------------------------RDRKYLA---R----LKLPPLSKCEA------LRESLDLGFEGMCL-EQPIGKRLFQQFLRTH-EQHGP----A----LQLWKDIEDYD-TADDALRPQKAQAL---RAAYLEPQA-QL-FCSFLDAETVARA-RA-----G---G--LFQPLLRAVLAHLGQAPFQEFLDSLYFLRFLQWKWLEAQ-PMGEDWFLDFRVLGRGGFGEVFACQM---K---A---TGKLYACKKLNKKRL-KKRKGY-QGAMV-EKKILAKV---HSRFIVSLAYAFETKTDLCLVMTIMNGGDIR---YHI----YNVDEDNPG--FQEPRAIFYTAQIVSGLEHLHQ-RNIIYRDLKPENVLLDDDGNVRISDLGLAVE-L--K---AGQT-K-T-K-GYA--GTPGFMAPE-LLL-GEEYDFSVDYFALGVTLYEMIAARGPFRARGEKVE--N-K-ELKQRVLEQAVTYPDKFSPASKDFCEALLQKDPEKRLGFR-D-GSCDGLRTHPLFRDISWRQLEAGMLTPPFVPDSRTVYAKN----GAFS------GVAFE---------KA--------DTEFFQEFA-SGTCPIPWQEEMIETGV-FGDLNVWRP-----------------------------------------------------------------------------------------------------------------------------------------------------------
29 PsiBlast_CBE 63.9634% -94 - C1 -3C4X RK_BOVIN A:[30-529] ---------------------------SRDR---KYLAR----LKLPPLSKCEA--LRESLD----LGFEGMCL-EQPIGKRLFQQFLRTH-EQHGP----A----LQLWKDIEDYDTAD-DALRPQKAQAL---RAAYLEPQAQLF-CSFLDAETVARAR-AG------AGDG--LFQPLLRAVLAHLGQAPFQEFLDSLYFLRFLQWKWLEAQ-PMGEDWFLDFRVLGRGGFGEVFACQM---K---A---TGKLYACKKLNKKRL-KKRKGY-QGAMV-EKKILAKVHS---RFIVSLAYAFETKTDLCLVMTIMNGGDIR---YHIYNVDEDNP----G--FQEPRAIFYTAQIVSGLEHLHQ-RNIIYRDLKPENVLLDDDGNVRISDLGLAVE-LKAG---Q--T-K-T-K-GYA--GTPGFMAPE-LLL-GEEYDFSVDYFALGVTLYEMIAARGPFRARGEKVE--N-K-ELKQRVLEQAVTYPDKFSPASKDFCEALLQKDPEKRLGFR-D-GSCDGLRTHPLFRDISWRQLEAGMLTPPFVPD--------IQDVGAFST--VK-GVAFE---------KA--------DTEFFQEFA-SGTCPIPWQEEMIETGV-FGDLNVWRP-----------------------------------------------------------------------------------------------------------------------------------------------------------
16 PsiBlast_PDB 63.9538% -95 - C1 -4TND GRK5_HUMAN A:[60-526] ----------------------------------------------------------------------------QPIGRLLFRQFC-----ETRPGLECY----IQFLDSVAEYE-VTPDEKLGEKGKKI---MTKYLTPKS-PV-FIAQVGQDLVSQT-EEKLLQKPCK-E--LFSACAQSVHEYLRGEPFHEYLDSMFFDRFLQWKWLERQ-PVTKNTFRQYRVLGKGGFGEVCACQV---R---A---TGKMYACKRLEKKRI-KKRKGE-SMALN-EKQILEKVNS---QFVVNLAYAYETKDALCLVLTIMNGGDLK---FHI----YNMG----NPGFEEERALFYAAEILCGLEDLHH-ENTVYRDLKPENILLDDYGHIRISDLGLAVK-I--P---E--G-DLI-R-GRV--GTVGYMAPE-VLNNQ-RYGLSPDYWGLGCLIYEMIEGQSPFRGRKEK-V--KRE-EVDRRVLETEEVYSHKFSEEAKSICKMLLTKDAKQRLGCQ-E-EEAAEVKRHPFFRNMNFKRLEAGMLDPPFVPDPRAVYCKDVLDIEQFS--TVK-GVNLD---------HT--------DDDFYSKFS-TGSVSIPWQNEMIETEC-FKELNVFGPNGTLPPDLNRNHPP---------------------------------------------------------------------------------------------------------------------------------------------
97 HHSearch 63.8339% -95 - C1 -2ACX GRK6_HUMAN A:[14-526] --------------KAR---------KGK-S---K---KWRQMLQFPHISQC------EELRLSLERDYHSLCE-RNPIGRLLFREFCATR-PELSR----C----VAFLDGVAEYEVTP-DDKRKACGRNL---TQNFLSHTG-PD-LIPEVPRQLVTNC-TQRLE-QGPCKD--LFQELTRLTHEYLSVAPFADYLDSIYFNRFLQWKWLERQ-PVTKNTFRQYRVLGKGGFGEVCACQV---R---A---TGKMYACKKLEKKRI-KKRKGE-AMALN-EKQILEKV---NSRFVVSLAYAYETKDALCLVLTLMNGGDLK---FHI----YHMGQA--G--FPEARAVFYAAEICCGLEDLHR-ERIVYRDLKPENILLDDHGHIRISDLGLAVH-V--P---E--GQT-I-K-GRV--GTVGYMAPE-VVK-NERYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIK--R-E-EVERLVKEVPEEYSERFSPQARSLCSQLLCKDPAERLGCR-G-GSAREVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYC--------------------E---------PT--------DQDFYQKFA-TGSVPIPWQNEMVET-ECFQELNVFGLDGS--------------------------------------------------------------------------------------------------------------------------------------------------------
25 PsiBlast_CBE 63.5534% -94 - C1 -3C51 RK_BOVIN A:[31-529] ----------------------------RDR---KYLAR----LKLPPLSKCEA--LRESLD----LGFEGMCL-EQPIGKRLFQQFLRTH-EQHGP----A----LQLWKDIEDYDTAD-DALRPQKAQAL---RAAYLEPQAQLF-CSFLDAETVARAR-AG---------G--LFQPLLRAVLAHLGQAPFQEFLDSLYFLRFLQWKWLEAQ-PMGEDWFLDFRVLGRGGFGEVFACQM---K---A---TGKLYACKKLNKKRL-KKRKGY-QGAMV-EKKILAKVHS---RFIVSLAYAFETKTDLCLVMTIMNGGDIR---YHIYNVDEDNP----G--FQEPRAIFYTAQIVSGLEHLHQ-RNIIYRDLKPENVLLDDDGNVRISDLGLAVE-LKAG---Q--T-K-T-K-GYA--GTPGFMAPE-LLL-GEEYDFSVDYFALGVTLYEMIAARGPFRARGEKVE--N-K-ELKQRVLEQAVTYPDKFSPASKDFCEALLQKDPEKRLGFR-D-GSCDGLRTHPLFRDISWRQLEAGMLTPPFVPDSR-------------ST--VK-GVAFE---------KA--------DTEFFQEFA-SGTCPIPWQEEMIETGV-FGDLNVWRP-----------------------------------------------------------------------------------------------------------------------------------------------------------
86 Fugue 63.5034% -86 - C1 -3C4Z RK_BOVIN A:[31-533] -------------------------RDRKYL---A---R----LKLPP----LS--KCEALRESLDLGFEGM-CLEQPIGKRLFQQFLRTH-EQHGP----A----LQLWKDIEDYD-TADDALRPQKAQAL---RAAYLEPQ----------AQLFCSFL-DAETVARARAGG--LFQPLLRAVLAHLGQAPFQEFLDSLYFLRFLQWKWLEAQ-PMGEDWFLDFRVLGRGGFGEVFACQM---K---A---TGKLYACKKLNKKRL-KKRKGY-QGAMV-EKKILAKVHS---RFIVSLAYAFETKTDLCLVMTIMNGGDIR---YHIYNVDEDNP----G--FQEPRAIFYTAQIVSGLEHLHQ-RNIIYRDLKPENVLLDDDGNVRISDLGLAVE-L--KAG-Q--T-K-T-K-GYA--GTPGFMAPE-LL-LGEEYDFSVDYFALGVTLYEMIAARGPFRARGEKVE--N-K-ELKQRVLEQAVTYPDKFSPASKDFCEALLQKDPEKRLGFR-D-GSCDGLRTHPLFRDISWRQLEAGMLTPPFVPDSRTVYAKN---------GAFS-GVAFE---------KA--------DTEFFQEFA-SGTCPIPWQEEMIETGV-FGDLNVWRP-----------------------------------------------------------------------------------------------------------------------------------------------------------
20 PsiBlast_PDB 62.9336% -83 - C1 -4YHJ ? A:[25-525] ---------------------------GRSK---KWKEI----LTLPPVSQCSE--LRHSIEKDYSSLCDK-----QPIGRRLFRQFC-----DTKP----TLKRHIEFLDAVAEYE-VADDEDRSDCGLSI---LDRFFNDKL-AA----PLPEIPPDVVTECRLGLKEENPSKKAFEECTRVAHNYLRGEPFEEYQESSYFSQFLQWKWLERQ-PVTKNTFRHYRVLGKGGFGEVCACQV---R---A---TGKMYACKKLQKKRI-KKRKGE-AMALN-EKRILEKVQSR---FVVSLAYAYETKDALCLVLTIMNGGDLK---FHI----YNLG----NPGFDEQRAVFYAAELCCGLEDLQR-ERIVYRDLKPENILLDDRGHIRISDLGLATE-I--P---EG-Q-R-V-R-GRV--GTVGYMAPE-VVNNE-KYTFSPDWWGLGCLIYEMIQGHSPFKKYKEK-V--KWE-EVDQRIKNDTEEYSEKFSEDAKSICRMLLTKNPSKRLGCR-G-EGAAGVKQHPVFKDINFRRLEANMLEPPFCPDPHAVYCKDVLDIEQFSV--VK-GIYLD---------TA--------DEDFYARFA-TGCVSIPWQNEMIESGC-FKDI----------------------------------------------------------------------------------------------------------------------------------------------------------------
24 PsiBlast_CBE 62.8336% -83 - C1 -4YHJ ? B:[25-526] ---------------------------GRSK---KWKEI----LTLPPVSQCSE--LRHSIEKDYSSLCDK-----QPIGRRLFRQFC-----DTKP----TLKRHIEFLDAVAEYE-VADDEDRSDCGLSI---LDRFFNDKL-AA----PLPEIPPDVVTECRLGLKEENPSKKAFEECTRVAHNYLRGEPFEEYQESSYFSQFLQWKWLERQ-PVTKNTFRHYRVLGKGGFGEVCACQV---R---A---TGKMYACKKLQKKRI-KKRKGE-AMALN-EKRILEKVQSR---FVVSLAYAYETKDALCLVLTIMNGGDLK---FHI----YNLG----NPGFDEQRAVFYAAELCCGLEDLQR-ERIVYRDLKPENILLDDRGHIRISDLGLATE-I--P---EG-Q-R-V-R-GRV--GTVGYMAPE-VVNNE-KYTFSPDWWGLGCLIYEMIQGHSPFKKYKEK-V--KWE-EVDQRIKNDTEEYSEKFSEDAKSICRMLLTKNPSKRLGCR-G-EGAAGVKQHPVFKDINFRRLEANMLEPPFCPDPHAVYC----------------GIYLD---------TA--------DEDFYARFA-TGCVSIPWQNEMIESGC-FKDINK--------------------------------------------------------------------------------------------------------------------------------------------------------------
39 PsiBlast_CBE 62.3635% -98 - C1 -4L9I RK_BOVIN A:[26-500] -----------------------------------------------------------------DLGFEGMCL-EQPIGKRLFQQFLRTH-EQHGP----A----LQLWKDIEDYDTAD-DALRPQKAQAL---RAAYLEPQAQLF-CSFLDAETVARAR-AG------AGDG--LFQPLLRAVLAHLGQAPFQEFLDSLYFLRFLQWKWLEAQ-PMGEDWFLDFRVLGRGGFGEVFACQM---K---A---TGKLYACKKLNKKRL-KKRKGY-QGAMV-EKKILAKVHS---RFIVSLAYAFETKTDLCLVMTIMNGGDIR---YHIYNVDEDNP----G--FQEPRAIFYTAQIVSGLEHLHQ-RNIIYRDLKPENVLLDDDGNVRISDLGLAVE-LKAG---Q--T-K-T-K-GYA--GTPGFMAPE-LLL-GEEYDFSVDYFALGVTLYEMIAARGPFRARGEKVE--N-K-ELKQRVLEQAVTYPDKFSPASKDFCEALLQKDPEKRLGFR-D-GSCDGLRTHPLFRDISWRQLEAGMLTPPFVPDSRTVYAKNIQDVGAFST--VK-GVAFE---------KA--------DTEFFQEFA-SGTCPIPWQEEMIETGV-FGDLNVWRP-----------------------------------------------------------------------------------------------------------------------------------------------------------
15 PsiBlast_PDB 62.1038% -93 - C1 -4TNB GRK5_HUMAN A:[60-526] ----------------------------------------------------------------------------QPIGRLLFRQFC-----ETRPGLECY----IQFLDSVAEYE-VTPDEKLGEKGKKI---MTKYLTPKS-PV-FIAQVGQDLVSQT-EEKLLQKPCK-E--LFSACAQSVHEYLRGEPFHEYLDSMFFDRFLQWKWLERQ-PVTKNTFRQYRVLGKGGFGEVCACQV---R---A---TGKMYACKRLEKKRI-KKRKGE-SMALN-EKQILEKVNS---QFVVNLAYAYETKDALCLVLTIMNGGDLK---FHI----YNMG----NPGFEEERALFYAAEILCGLEDLHH-ENTVYRDLKPENILLDDYGHIRISDLGLAVK-I--P---E--G-DLI-R-GRV--GTVGYMAPE-VLNNQ-RYGLSPDYWGLGCLIYEMIEGQSPFRGRKEK-V--KRE-EVDRRVLETEEVYSHKFSEEAKSICKMLLTKDAKQRLGCQ-E-EEAAEVKRHPFFRNMNFKRLEAGMLDPPFVPDPRAVYCKDVLDIEQFS--TVK-GVNLD---------HT--------DDDFYSKFS-TGSVSIPWQNEMIETEC-FKELNVFGPNGTLPPDLNRNHPP---------------------------------------------------------------------------------------------------------------------------------------------
19 PsiBlast_PDB 60.8838% -88 - C1 -2ACX GRK6_HUMAN A:[14-526] --------------KAR---------KGKSK---KW--R----QMLQFPHISQCEELRLSLERDYHSLCER-----NPIGRLLFREFCATRPELSR-----C----VAFLDGVAEYE-VTPDDKRKACGRNLTQNFLSHTGPDL-IPEVPRQLVTNCTQRL-EQGPCK-----D--LFQELTRLTHEYLSVAPFADYLDSIYFNRFLQWKWLERQ-PVTKNTFRQYRVLGKGGFGEVCACQV---R---A---TGKMYACKKLEKKRI-KKRKGE-AMALN-EKQILEKVNSR---FVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHM----GQAG-------FPEARAVFYAAEICCGLEDLHR-ERIVYRDLKPENILLDDHGHIRISDLGLAVH-V--P---E--G-Q-TIK-GRV--GTVGYMAPE-VV-KNERYTFSPDWWALGCLLYEMIAGQSPFQQRKKK-I--K-REEVERLVKEVPEEYSERFSPQARSLCSQLLCKDPAERLGCR-G-GSAREVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYC--------------------E---------PT--------DQDFYQKFA-TGSVPIPWQNEMVETEC-FQELNVFGLDGS--------------------------------------------------------------------------------------------------------------------------------------------------------
23 PsiBlast_CBE 60.6438% -89 - C1 -2ACX GRK6_HUMAN B:[14-526] --------------KAR---------KGKSK---KW--R----QMLQFPHISQCEELRLSLERDYHSLCER-----NPIGRLLFREFCATRPELSR-----C----VAFLDGVAEYE-VTPDDKRKACGRNLTQNFLSHTGPDL-IPEVPRQLVTNCTQRL-EQGPCK-----D--LFQELTRLTHEYLSVAPFADYLDSIYFNRFLQWKWLERQ-PVTKNTFRQYRVLGKGGFGEVCACQV---R---A---TGKMYACKKLEKKRI-KKRKGE-AMALN-EKQILEKVNSR---FVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHM------AG-------FPEARAVFYAAEICCGLEDLHR-ERIVYRDLKPENILLDDHGHIRISDLGLAVH-V--P---E--G-Q-TIK-GRV--GTVGYMAPE-VV-KNERYTFSPDWWALGCLLYEMIAGQSPFQQ---K-I--K-REEVERLVKEVPEEYSERFSPQARSLCSQLLCKDPAERLGCR-G-GSAREVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIY---------------------E---------PT--------DQDFYQKFA-TGSVPIPWQNEMVETEC-FQELNVFGLDGSVPP-----------------------------------------------------------------------------------------------------------------------------------------------------
108 HHSearch 52.2033% -98 - C1 -4DC2 KPCI_MOUSE A:[49-384] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LGLQDFDLLRVIGRGSYAKVLLVRL---K---K---TDRIYAMRVVKKELV-N----I-DWVQT-EKHVFEQA--SNHPFLVGLHSCFQTESRLFFVIEYVNGGDLM---FHM----QRQR----K--LPEEHARFYSAEISLALNYLHE-RGIIYRDLKLDNVLLDSEGHIKLTDYGMCKE-G--L---RPGD-T-T-S-TFC--GTPNYIAPE-ILR-GEDYGFSVDWWALGVLMFEMMAGRSPFDIVGS---NTE-D-YLFQVILEKQIRIPRSLSVKAASVLKSFLNKDPKERLGCHPQ-TGFADIQGHPFFRNVDWDMMEQKQVVPPFKPNI-----SGEFGLDNFDSQFTNEPVQLT---------PDDDDIVRKIDQSEFEGFE-Y-INP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
99 HHSearch 51.8638% -98 - C1 -4GV1 AKT1_HUMAN A:[4-304] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RVTMNEFEYLKLLGKGTFGKVILVKE---K---A---TGRYYAMKILKKEVI-VAKDEV-AHTLT-ENRVLQNS---RHPFLTALKYSFQTHDRLCFVMEYANGGELF---FHL----SRER----V--FSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKE-G--I---KDGA-T-M-K-TFC--GTPEYLAPE-VLE-DNDYGRAVDWWGLGVVMYEMMCGRLPFYNQ----D--H-E-KLFELILMEEIRFPRTLGPEAKSLLSGLLKKDPKQRLGGG-S-EDAKEIMQHRFFAGIVWQHVYEKKLSPPFKPQV-----TSETDTRYFDEEFTA-QMITI---------TP--------SMECVDSER-R-PHFPQFDYSAS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------
113 HHSearch 51.0338%-102 - C1 -4EJN AKT1_HUMAN A:[144-438] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RVTMNEFEYLKLLGKGTFGKVILVKE---K---A---TGRYYAMKILKKEVI-V---------------VLQN---SRHPFLTALKYSFQTHDRLCFVMEYANGGELF---FHL----SRER----V--FSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKE-G--I---K--------K-TFC--GTPEYLAPE-VLE-DNDYGRAVDWWGLGVVMYEMMCGRLPFYN---Q-D--H-E-KLFELILMEEIRFPRTLGPEAKSLLSGLLKKDPKQRLGGG-S-EDAKEIMQHRFFAGIVWQHVYEKKLSPPFKPQV-----TSETDTRYF-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
42 PsiBlast_CBE 49.9237% -95 - C1 -4NW5 KS6A3_HUMAN A:[30-322] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SQFELLKVLGQGSFGKVFLVKKISGS---D---ARQLYAMKVLKKATL-KVRDRV-RTKME-RDILVEV----NHPFIVKLHYAFQTEGKLYLILDFLRGGDLF---TRL----SKEV----M--FTEEDVKFYLAELALALDHLHS-LGIIYRDLKPENILLDEEGHIKLTDFGLSKE-SIDH---E--K-K-A-Y-SFC--GTVEYMAPE-VVNRR-GHTQSADWWSFGVLMFEMLTGTLPF---QGK-D--R-K-ETMTMILKAKLGMPQFLSPEAQSLLRMLFKRNPANRLGAG-P-DGVEEIKRHSFFSTIDWNKLYRREIHPPFKP-------TFYFDP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
43 PsiBlast_CBE 49.8437% -99 - C1 -4NUS KS6A3_HUMAN A:[30-322] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SQFELLKVLGQGSFGKVFLVKKISGS---D---ARQLYAMKVLKKATL-KVRDRV-RTKME-RDILVEV----NHPFIVKLHYAFQTEGKLYLILDFLRGGDLF---TRL----SKEV----M--FTEEDVKFYLAELALALDHLHS-LGIIYRDLKPENILLDEEGHIKLTDFGLSKE-SIDH---E--K-K-A-Y-SFC--GTVEYMAPE-VVNRR-GHTQSADWWSFGVLMFEMLTGTLPF---QGK-D--R-K-ETMTMILKAKLGMPQFLSPEAQSLLRMLFKRNPANRLGAG-P-DGVEEIKRHSFFSTIDWNKLYRREIHPPFKPAT------FYFDP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
73 PsiBlast_CBE 49.5539% -98 - C1 -4L3J KS6B1_HUMAN A:[20-300] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FELLRVLGKGGYGKVFQVRKVTGA---N---TGKIFAMKVLKKAMI-VRNAKD-TAHTKAERNILEEVKH---PFIVDLIYAFQTGGKLYLILEYLSGGELF---MQL----EREG----I--FMEDTACFYLAEISMALGHLHQ-KGIIYRDLKPENIMLNHQGHVKLTDFGL-CK-E--SIHDG--T-V-T-H-TFC--GTIEYMAPE-ILMRS-GHNRAVDWWSLGALMYDMLTGAPPFTGENRK-K--T----IDKI-LKCKLNLPPYLTQEARDLLKKLLKRNAASRLGAG-P-GDAGEVQAHPFFRHINWEELLARKVEPPFKPLLQS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
45 PsiBlast_CBE 49.2737%-107 - C1 -5D9K ? B:[30-322] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SQFELLKVLGQGSFGKVFLVKKISGS---D---ARQLYAMKVLKKATL-KVRDRV-RTKME-RDILVEV----NHPFIVKLHYAFQTEGKLYLILDFLRGGDLF---TRL----SKEV----M--FTEEDVKFYLAELALALDHLHS-LGIIYRDLKPENILLDEEGHIKLTDFGLSKE---------------------C--GTVEYMAPE-VVNRR-GHTQSADWWSFGVLMFEMLTGTLPF---QGK-D--R-K-ETMTMILKAKLGMPQFLSPEAQSLLRMLFKRNPANRLGAG-P-DGVEEIKRHSFFSTIDWNKLYRREIHPPFKP-------TFYFDP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
115 HHSearch 49.2238%-101 - C1 -3WF7 KS6B1_HUMAN A:[16-304] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IRPECFELLRVLGKGGYGKVFQVRK---VTGAN---TGKIFAMKVLKKAMI-VRNAKDTAHTKA-ERNILEEV---KHPFIVDLIYAFQTGGKLYLILEYLSGGELF---MQL----EREG----I--FMEDTACFYLAEISMALGHLHQ-KGIIYRDLKPENIMLNHQGHVKLTDFGLCKE-S--IHD--------T-H-TFC--GTIEYMAPE-ILM-RSGHNRAVDWWSLGALMYDMLTGAPPFTGENRK------K-TIDKI-LKCKLN