@TOME V2.3
(Nov 2016)

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3D Common Core:

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Modeller Result :

Complexes Modeling
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Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : AVR2A_HUMAN: (2015-10-03 )
MGAAAKLAFAVFLISCSSGAILGRSETQECLFFNANWEKDRTNQTGVEPCYGDKDKRRHCFATWKNISGSIEIVKQGCWLDDINCYDRTDCVEKKDSPEVYFCCCEGNMCNEKFSYFPEMEVTQPTSNPVTPKPPYYNILLYSLVPLMLIAGIVICAFWVYRHHKMAYPPVLVPTQDPGPPPPSPLLGLKPLQLLEVKARGRFGCVWKAQLLNEYVAVKIFPIQDKQSWQNEYEVYSLPGMKHENILQFIGAEKRGTSVDVDLWLITAFHEKGSLSDFLKANVVSWNELCHIAETMARGLAYLHEDIPGLKDGHKPAISHRDIKSKNVLLKNNLTACIADFGLALKFEAGKSAGDTHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWELASRCTAADGPVDEYMLPFEEEIGQHPSLEDMQEVVVHKKKRPVLRDYWQKHAGMAMLCETIEECWDHDAEARLSAGCVGERITQMQRLTNIITTEDIVTVVTMVTNVDFPPKESSL

Atome Classification :

(37 SA) .........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190-........200.......210.------------------......220...-------.----...230.......240.......250.......260.......270.......280---.-----.......290.......300.......310........320.......330.......340.......350..--.--.--...360.......370....---..-.-380.......390.......400.......410........420-.......430---.......440.......450........460.......470.......480.......490.......500.......510.
(Atome) (Ident) (Tito) (Num) (Ligand) (Uniprot) MGAAAKLAFAVFLISCSSGAILGRSETQECLFFNANWEKDRTNQTGVEPCYGDKDKRRHCFATWKNISGSIEIVKQGCWLDDINCYDRTDCVEKKDSPEVYFCCCEGNMCNEKFSYFPEMEVTQPTSNPVTPKPPYYNILLYSLVPLMLIAGIVICAFWVYRHHKMAYPPVLVPTQDPGPPPPSPLLGLKP--LQLLEVKARGRFGCVWKAQLLN------------------EYVAVKIFPIQD-------K----QSWQNEYEVYSLPGMKHENILQFIGAEKRGTSVDVDLWLITAFHEKGSLSDFLKA----N-----VVSWNELCHIAETMARGLAYLHEDIPGLK-DGHKPAISHRDIKSKNVLLKNNLTACIADFGLALKFEAGKSAG--D--T--HGQVGTRRYMAPEVLEGAIN---FQ-R-DAFLRIDMYAMGLVLWELASRCTAADGPVDE-YMLPFEEEIGQH-PSLEDMQEVV---VHKKKRPVLRDYWQKHAG-MAMLCETIEECWDHDAEARLSAGCVGERITQMQRLTNIITTEDIVTVVTMVTNVDFPPKESSL
23 PsiBlast_CBE 97.39100%-106 - C2 -3Q4T AVR2A_HUMAN B:[25-319] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------P--LQLLEVKARGRFGCVWKAQLLN------------------EYVAVKIFPIQD-------K----QSWQNEYEVYSLPGMKHENILQFIGAEKRGTSVDVDLWLITAFHEKGSLSDFLKA----N-----VVSWNELCHIAETMARGLAYLHEDIPGLK-DGHKPAISHRDIKSKNVLLKNNLTACIADFGLALKFEAGKSA------T--HGQVGTRRYMAPEVLEGAIN---FQ-R-DAFLRIDMYAMGLVLWELASRCTAADGPVDE-YMLPFEEEIGQH-PSLEDMQEVV---VHKKKRPVLRDYWQKHAG-MAMLCETIEECWDHDAEARLSAGCVGERITQMQRL----------------------------
22 PsiBlast_CBE 96.64100%-105 - C2 -3SOC AVR2A_HUMAN B:[25-320] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------P--LQLLEVKARGRFGCVWKAQLLN------------------EYVAVKIFPIQD-------K----QSWQNEYEVYSLPGMKHENILQFIGAEKRGTSVDVDLWLITAFHEKGSLSDFLKA----N-----VVSWNELCHIAETMARGLAYLHEDIPGLK-DGHKPAISHRDIKSKNVLLKNNLTACIADFGLALKFEAGKSA------T--HGQVGTRRYMAPEVLEGAIN---FQ-R-DAFLRIDMYAMGLVLWELASRCTAADGPVDE-YMLPFEEEIGQH-PSLEDMQEVV---VHKKKRPVLRDYWQKHAG-MAMLCETIEECWDHDAEARLSAGCVGERITQMQRLT---------------------------
21 PsiBlast_CBE 95.67100%-101 - C2 -4ASX AVR2A_HUMAN B:[25-320] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------P--LQLLEVKARGRFGCVWKAQLLN------------------EYVAVKIFPIQD-------K----QSWQNEYEVYSLPGMKHENILQFIGAEKRGTSVDVDLWLITAFHEKGSLSDFLKA----N-----VVSWNELCHIAETMARGLAYLHEDIPGLK-DGHKPAISHRDIKSKNVLLKNNLTACIADFGLALKFEAGKSAG--D--T--HGQVGTRRYMAPEVLEGAIN---FQ-R-DAFLRIDMYAMGLVLWELASRCTAADGPVDE-YMLPFEEEIGQH-PSLEDMQEVV---VHKKKRPVLRDYWQKHAG-MAMLCETIEECWDHDAEARLSAGCVGERITQMQRLT---------------------------
3 PsiBlast_PDB 95.56100%-106 - C2 -4ASX AVR2A_HUMAN A:[25-320] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------P--LQLLEVKARGRFGCVWKAQLLN------------------EYVAVKIFPIQD-------K----QSWQNEYEVYSLPGMKHENILQFIGAEKRGTSVDVDLWLITAFHEKGSLSDFLKA----N-----VVSWNELCHIAETMARGLAYLHEDIPGLK-DGHKPAISHRDIKSKNVLLKNNLTACIADFGLALKFEAGKSAG-----T--HGQVGTRRYMAPEVLEGAIN---FQ-R-DAFLRIDMYAMGLVLWELASRCTAADGPVDE-YMLPFEEEIGQH-PSLEDMQEVV---VHKKKRPVLRDYWQKHAG-MAMLCETIEECWDHDAEARLSAGCVGERITQMQRLT---------------------------
1 PsiBlast_PDB 93.88100% -99 - C2 -3Q4T AVR2A_HUMAN A:[25-318] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------P--LQLLEVKARGRFGCVWKAQLLN------------------EYVAVKIFPIQD-------K----QSWQNEYEVYSLPGMKHENILQFIGAEKRGTSVDVDLWLITAFHEKGSLSDFLKA----N-----VVSWNELCHIAETMARGLAYLHEDIPGLK-DGHKPAISHRDIKSKNVLLKNNLTACIADFGLALKFEAGKSAG--D--T--HGQVGTRRYMAPEVLEGAIN---FQ-R-DAFLRIDMYAMGLVLWELASRCTAADGPVDE-YMLPFEEEIGQH-PSLEDMQEVV---VHKKKRPVLRDYWQKHAG-MAMLCETIEECWDHDAEARLSAGCVGERITQMQR-----------------------------
2 PsiBlast_PDB 93.23100% -98 - C2 -3SOC AVR2A_HUMAN A:[25-320] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------P--LQLLEVKARGRFGCVWKAQLLN------------------EYVAVKIFPIQD-------K----QSWQNEYEVYSLPGMKHENILQFIGAEKRGTSVDVDLWLITAFHEKGSLSDFLKA----N-----VVSWNELCHIAETMARGLAYLHEDIPGLK-DGHKPAISHRDIKSKNVLLKNNLTACIADFGLALKFEAGKSAG--D--T--HGQVGTRRYMAPEVLEGAIN---FQ-R-DAFLRIDMYAMGLVLWELASRCTAADGPVDE-YMLPFEEEIGQH-PSLEDMQEVV---VHKKKRPVLRDYWQKHAG-MAMLCETIEECWDHDAEARLSAGCVGERITQMQRLT---------------------------
143 HHSearch 92.8597% -96 - C2 -3SOC AVR2A_HUMAN A:[16-320] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TENLYFQSMP--LQLLEVKARGRFGCVWKAQLLN------------------EYVAVKIFPIQD-------K----QSWQNEYEVYSLPGMKHENILQFIGAEKRGTSVDVDLWLITAFHEKGSLSDFLKA----N-----VVSWNELCHIAETMARGLAYLHEDIPGLK-DGHKPAISHRDIKSKNVLLKNNLTACIADFGLALKFEAGKSAG--D--T--HGQVGTRRYMAPEVLEGAIN---FQ-R-DAFLRIDMYAMGLVLWELASRCTAADGPVDE-YMLPFEEEIGQH-PSLEDMQEVV---VHKKKRPVLRDYWQKHAG-MAMLCETIEECWDHDAEARLSAGCVGERITQMQRLT---------------------------
4 PsiBlast_PDB 85.3576%-101 - C2 -2QLU AVR2B_HUMAN A:[15-311] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GSLQLLEIKARGRFGCVWKAQLMN------------------DFVAVKIFPLQD-------K----QSWQSEREIFSTPGMKHENLLQFIAAEKRGSNLEVELWLITAFHDKGSLTDYLKG----N-----IITWNELCHVAETMSRGLSYLHEDVPWCRGEGHKPSIAHRDFKSKNVLLKSDLTAVLADFGLAVRFEPGKPPG--D--T--HGQVGTRRYMAPEVLEGAIN---FQ-R-DAFLRIDMYAMGLVLWELVSRCKAADGPVDE-YMLPFEEEIGQH-PSLEELQEVV---VHKKMRPTIKDHWLKHPG-LAQLCVTIEECWDHDAEARLSAGCVEERVSLIRRS----------------------------
11 PsiBlast_PDB 74.5340% -94 - C2 -4X2G ? A:[5-303] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RT--IVLQESIGKGRFGEVWRGKWRG------------------EEVAVKIFSSRE-------E----RSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNR----Y-----TVTVEGMIKLALSTASGLAHLHMEIVGTQ-G--KPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTI--D--IAPNHRVGTKRYMAPEVLDDSIN---MK-HFESFKRADIYAMGLVFWEIARRCSIG-GIHED-YQLPYYDLVPSD-PSVEEMRKVV---CEQKLRPNIPNRWQSCEA-LRVMAKIMRECWYANGAARLTALRIKKTLSQLSQQEGI-------------------------
43 PsiBlast_CBE 74.0140% -93 - C2 -4X0M TGFR1_HUMAN A:[5-303] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RT--IVLQESIGKGRFGEVWRGKWRG------------------EEVAVKIFSSRE-------E----RSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNR----Y-----TVTVEGMIKLALSTASGLAHLHMEIVGTQ-G--KPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTI--D--IAPNHRVGTKRYMAPEVLDDSIN---MK-HFESFKRADIYAMGLVFWEIARRCSIG-GIHED-YQLPYYDLVPSD-PSVEEMRKVV---CEQKLRPNIPNRWQSCEA-LRVMAKIMRECWYANGAARLTALRIKKTLSQLSQQEGI-------------------------
42 PsiBlast_CBE 73.9440% -94 - C2 -4X2J TGFR1_HUMAN A:[5-303] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RT--IVLQESIGKGRFGEVWRGKWRG------------------EEVAVKIFSSRE-------E----RSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNR----Y-----TVTVEGMIKLALSTASGLAHLHMEIVGTQ-G--KPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTI--D--IAPNHRVGTKRYMAPEVLDDSIN---MK-HFESFKRADIYAMGLVFWEIARRCSIG-GIHED-YQLPYYDLVPSD-PSVEEMRKVV---CEQKLRPNIPNRWQSCEA-LRVMAKIMRECWYANGAARLTALRIKKTLSQLSQQEGI-------------------------
41 PsiBlast_CBE 73.9440% -94 - C2 -4X2K TGFR1_HUMAN A:[5-303] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RT--IVLQESIGKGRFGEVWRGKWRG------------------EEVAVKIFSSRE-------E----RSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNR----Y-----TVTVEGMIKLALSTASGLAHLHMEIVGTQ-G--KPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTI--D--IAPNHRVGTKRYMAPEVLDDSIN---MK-HFESFKRADIYAMGLVFWEIARRCSIG-GIHED-YQLPYYDLVPSD-PSVEEMRKVV---CEQKLRPNIPNRWQSCEA-LRVMAKIMRECWYANGAARLTALRIKKTLSQLSQQEGI-------------------------
14 PsiBlast_PDB 72.8040% -93 - C2 -2WOT TGFR1_HUMAN A:[6-303] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RT--IVLQESIGKGRFGEVWRGKWRG------------------EEVAVKIFSSRE-------E----RSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNR----Y-----TVTVEGMIKLALSTASGLAHLHMEIVGTQ-G--KPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTI--D--IAPNHRVGTKRYMAPEVLDDSIN---MK-HFESFKRADIYAMGLVFWEIARRCSIG-GIHED-YQLPYYDLVPSD-PSVEEMRKVV---CEQKLRPNIPNRWQSCEA-LRVMAKIMRECWYANGAARLTALRIKKTLSQLSQQEG--------------------------
19 PsiBlast_PDB 72.5040% -93 - C2 -3H9R ACVR1_HUMAN A:[37-329] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RQ--ITLLECVGKGRYGEVWRGSWQG------------------ENVAVKIFSSRD-------E----KSWFRETELYNTVMLRHENILGFIASDMTS---STQLWLITHYHEMGSLYDYLQL----T-----TLDTVSCLRIVLSIASGLAHLHIEIFGTQ-G--KPAIAHRDLKSKNILVKKNGQCCIADLGLAVMH-----------------RVGTKRYMAPEVLDETIQ---VDCF-DSYKRVDIWAFGLVLWEVARR-MVSNGIVED-YKPPFYDVVPND-PSFEDMRKVV---CVDQQRPNIPNRWFSDPT-LTSLAKLMKECWYQNPSARLTALRIKKTLTKID------------------------------
8 PsiBlast_PDB 71.7640% -94 - C2 -3TZM TGFR1_HUMAN A:[9-302] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RT--IVLQESIGKGRFGEVWRGKWRG------------------EEVAVKIFSSRE-------E----RSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNR----Y-----TVTVEGMIKLALSTASGLAHLHMEIVGTQ-G--KPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTI--D--IAP--RVGTKRYMAPEVLDDSIN---MK-HFESFKRADIYAMGLVFWEIARRCSIG-GIHED-YQLPYYDLVPSD-PSVEEMRKVV---CEQKLRPNIPNRWQSCEA-LRVMAKIMRECWYANGAARLTALRIKKTLSQLS------------------------------
49 PsiBlast_CBE 71.7040% -85 - C2 -4BGG ACVR1_HUMAN A:[8-300] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RD--ITLLECVGKGRYGEVWRGSWQG------------------ENVAVKIFSSRD-------E----KSWFRETELYNTVMLRHENILGFIASDMTSRHSSTQLWLITHYHEMGSLYDYLQL----T-----TLDTVSCLRIVLSIASGLAHLHIEIFGTQ-G--KPAIAHRDLKSKNILVKKNGQCCIADLGLAVMHSQSTNQL--DVGN--NPRVGTKRYMAPEVLDETIQ---VDCF-DSYKRVDIWAFGLVLWEVARR-MVSNGIVED-YKPPFYDVVPND-PSFEDMRKVV---CVDQQRPNIPNRWFSDPT-LTSLAKLMKECWYQNPSARLTALRIKKTLTKI-------------------------------
20 PsiBlast_PDB 71.5040% -89 - C2 -4C02 ACVR1_HUMAN A:[37-329] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RQ--ITLLECVGKGRYGEVWRGSWQG------------------ENVAVKIFSSRD-------E----KSWFRETELYNTVMLRHENILGFIASDMTSR--STQLWLITHYHEMGSLYDYLQL----T-----TLDTVSCLRIVLSIASGLAHLHIEIFGTQ-G--KPAIAHRDLKSKNILVKKNGQCCIADLGLAVMHSQSTNQL--DV-----PRVGTKRYMAPEVLDETIQ---VDCF-DSYKRVDIWAFGLVLWEVARR-MVSNGIVED-YKPPFYDVVPND-PSFEDMRKVV---CVDQQRPNIPNRWFSDPT-LTSLAKLMKECWYQNPSARLTALRIKKTLTKID------------------------------
15 PsiBlast_PDB 71.4940% -94 - C2 -2WOU TGFR1_HUMAN A:[6-299] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RT--IVLQESIGKGRFGEVWRGKWRG------------------EEVAVKIFSSRE-------E----RSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNR----Y-----TVTVEGMIKLALSTASGLAHLHMEIVGTQ-G--KPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTI--D--IAPNHRVGTKRYMAPEVLDDSIN---MK-HFESFKRADIYAMGLVFWEIARRCSIG-GIHED-YQLPYYDLVPSD-PSVEEMRKVV---CEQKLRPNIPNRWQSCEA-LRVMAKIMRECWYANGAARLTALRIKKTLSQLS------------------------------
51 PsiBlast_CBE 71.4240% -81 - C2 -3Q4U ACVR1_HUMAN C:[8-300] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RD--ITLLECVGKGRYGEVWRGSWQG------------------ENVAVKIFSSRD-------E----KSWFRETELYNTVMLRHENILGFIASDMTSRHSSTQLWLITHYHEMGSLYDYLQL----T-----TLDTVSCLRIVLSIASGLAHLHIEIFGTQ-G--KPAIAHRDLKSKNILVKKNGQCCIADLGLAVMHSQSTNQL--DVGN--NPRVGTKRYMAPEVLDETIQ---VDCF-DSYKRVDIWAFGLVLWEVARR-MVSNGIVED-YKPPFYDVVPND-PSFEDMRKVV---CVDQQRPNIPNRWFSDPT-LTSLAKLMKECWYQNPSARLTALRIKKTLTKID------------------------------
53 PsiBlast_CBE 71.3240% -84 - C2 -3Q4U ACVR1_HUMAN A:[8-300] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RD--ITLLECVGKGRYGEVWRGSWQG------------------ENVAVKIFSSRD-------E----KSWFRETELYNTVMLRHENILGFIASDMTSRHSSTQLWLITHYHEMGSLYDYLQL----T-----TLDTVSCLRIVLSIASGLAHLHIEIFGTQ-G--KPAIAHRDLKSKNILVKKNGQCCIADLGLAVMHSQSTNQL--DVGN--NPRVGTKRYMAPEVLDETIQ---VDCF-DSYKRVDIWAFGLVLWEVARR-MVSNGIVED-YKPPFYDVVPND-PSFEDMRKVV---CVDQQRPNIPNRWFSDPT-LTSLAKLMKECWYQNPSARLTALRIKKTLTKID------------------------------
48 PsiBlast_CBE 71.3140% -87 * C2 *4BGG ACVR1_HUMAN B:[8-300] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RD--ITLLECVGKGRYGEVWRGSWQG------------------ENVAVKIFSSRD-------E----KSWFRETELYNTVMLRHENILGFIASDMTSRHSSTQLWLITHYHEMGSLYDYLQL----T-----TLDTVSCLRIVLSIASGLAHLHIEIFG------KPAIAHRDLKSKNILVKKNGQCCIADLGLAVMHSQSTNQL--DVGN--NPRVGTKRYMAPEVLDETIQ---VDCF-DSYKRVDIWAFGLVLWEVARR-MVSNGIVED-YKPPFYDVVPND-PSFEDMRKVV---CVDQQRPNIPNRWFSDPT-LTSLAKLMKECWYQNPSARLTALRIKKTLTKI-------------------------------
47 PsiBlast_CBE 71.2440% -88 - C2 -