@TOME V2.3
(Nov 2016)

Ref. - - Doc.
Global output mode :
Sort entries by :
Sequence Color type :

Show alignment :
Column output:
Score:

Alignment:

3D Common Core:

Structural Clustering:

Modeller Result :

Complexes Modeling
Templates Information:
Sequence & Result Tab:

Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : BMPR2_HUMAN: (2015-10-04 )
MTSSLQRPWRVPWLPWTILLVSTAAASQNQERLCAFKDPYQQDLGIGESRISHENGTILCSKGSTCYGLWEKSKGDINLVKQGCWSHIGDPQECHYEECVVTTTPPSIQNGTYRFCCCSTDLCNVNFTENFPPPDTTPLSPPHSFNRDETIIIALASVSVLAVLIVALCFGYRMLTGDRKQGLHSMNMMEAAASEPSLDLDNLKLLELIGRGRYGAVYKGSLDERPVAVKVFSFANRQNFINEKNIYRVPLMEHDNIARFIVGDERVTADGRMEYLLVMEYYPNGSLCKYLSLHTSDWVSSCRLAHSVTRGLAYLHTELPRGDHYKPAISHRDLNSRNVLVKNDGTCVISDFGLSMRLTGNRLVRPGEEDNAAISEVGTIRYMAPEVLEGAVNLRDCESALKQVDMYALGLIYWEIFMRCTDLFPGESVPEYQMAFQTEVGNHPTFEDMQVLVSREKQRPKFPEAWKENSLAVRSLKETIEDCWDQDAEARLTAQCAEERMAELMMIWERNKSVSPTVNPMSTAMQNERNLSHNRRVPKIGPYPDYSSSSYIEDSIHHTDSIVKNISSEHSMSSTPLTIGEKNRNSINYERQQAQARIPSPETSVTSLSTNTTTTNTTGLTPSTGMTTISEMPYPDETNLHTTNVAQSIGPTPVCLQLTEEDLETNKLDPKEVDKNLKESSDENLMEHSLKQFSGPDPLSSTSSSLLYPLIKLAVEATGQQDFTQTANGQACLIPDVLPTQIYPLPKQQNLPKRPTSLPLNTKNSTKEPRLKFGSKHKSNLKQVETGVAKMNTINAAEPHVVTVTMNGVAGRNHSVNSHAATTQYANGTVLSGQTTNIVTHRAQEMLQNQFIGEDTRLNINSSPDEHEPLLRREQQAGHDEGVLDRLVDRRERPLEGGRTNSNNNNSNPCSEQDVLAQGVPSTAADPGPSKPRRAQRPNSLDLSATNVLDGSSIQIGESTQDGKSGSGEKIKKRVKTPYSLKRWRPSTWVISTESLDCEVNNNGSNRAVHSKSSTAVYLAEGGTATTMVSKDIGMNCL

Atome Classification :

(33 SA) .........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.-........330.......340.......350.......360.......370...---....380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570.......580.......590.......600.......610.......620.......630.......640.......650.......660.......670.......680.......690.......700.......710.......720.......730.......740.......750.......760.......770.......780.......790.......800.......810.......820.......830.......840.......850.......860.......870.......880.......890.......900.......910.......920.......930.......940.......950.......960.......970.......980.......990.......1000......1010......1020......1030.....
(Atome) (Ident) (Tito) (Num) (Ligand) (Uniprot) MTSSLQRPWRVPWLPWTILLVSTAAASQNQERLCAFKDPYQQDLGIGESRISHENGTILCSKGSTCYGLWEKSKGDINLVKQGCWSHIGDPQECHYEECVVTTTPPSIQNGTYRFCCCSTDLCNVNFTENFPPPDTTPLSPPHSFNRDETIIIALASVSVLAVLIVALCFGYRMLTGDRKQGLHSMNMMEAAASEPSLDLDNLKLLELIGRGRYGAVYKGSLDERPVAVKVFSFANRQNFINEKNIYRVPLMEHDNIARFIVGDERVTADGRMEYLLVMEYYPNGSLCKYLSLHTSDWVSSCRLAHSVTRGLAYLHTELP--R-GDHYKPAISHRDLNSRNVLVKNDGTCVISDFGLSMRLTGNRLVRPGEEDNAAIS---EVGTIRYMAPEVLEGAVNLRDCESALKQVDMYALGLIYWEIFMRCTDLFPGESVPEYQMAFQTEVGNHPTFEDMQVLVSREKQRPKFPEAWKENSLAVRSLKETIEDCWDQDAEARLTAQCAEERMAELMMIWERNKSVSPTVNPMSTAMQNERNLSHNRRVPKIGPYPDYSSSSYIEDSIHHTDSIVKNISSEHSMSSTPLTIGEKNRNSINYERQQAQARIPSPETSVTSLSTNTTTTNTTGLTPSTGMTTISEMPYPDETNLHTTNVAQSIGPTPVCLQLTEEDLETNKLDPKEVDKNLKESSDENLMEHSLKQFSGPDPLSSTSSSLLYPLIKLAVEATGQQDFTQTANGQACLIPDVLPTQIYPLPKQQNLPKRPTSLPLNTKNSTKEPRLKFGSKHKSNLKQVETGVAKMNTINAAEPHVVTVTMNGVAGRNHSVNSHAATTQYANGTVLSGQTTNIVTHRAQEMLQNQFIGEDTRLNINSSPDEHEPLLRREQQAGHDEGVLDRLVDRRERPLEGGRTNSNNNNSNPCSEQDVLAQGVPSTAADPGPSKPRRAQRPNSLDLSATNVLDGSSIQIGESTQDGKSGSGEKIKKRVKTPYSLKRWRPSTWVISTESLDCEVNNNGSNRAVHSKSSTAVYLAEGGTATTMVSKDIGMNCL
22 PsiBlast_CBE 90.1642% -72 - C1 -3SOC AVR2A_HUMAN B:[26-316] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LQLLEVKARGRFGCVWKAQLLNEYVAVKIFPIQDKQSWQNEYEVYSLPGMKHENILQFIGAEKRGTSVD-VDLWLITAFHEKGSLSDFLKANVVSWNELCHIAETMARGLAYLHEDIPG-L-KDGHKPAISHRDIKSKNVLLKNNLTACIADFGLALKF------EAGKSA--THG---QVGTRRYMAPEVLEGAINFQ--RDAFLRIDMYAMGLVLWELASRCTA--ADGPVDEYMLPFEEEIGQHPSLEDMQEVVVHKKKRPVLRDYWQKHA-GMAMLCETIEECWDHDAEARLSAGCVGERITQMQRLT--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23 PsiBlast_CBE 89.2142% -71 - C1 -3Q4T AVR2A_HUMAN B:[26-316] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LQLLEVKARGRFGCVWKAQLLNEYVAVKIFPIQDKQSWQNEYEVYSLPGMKHENILQFIGAEKRGTSVD-VDLWLITAFHEKGSLSDFLKANVVSWNELCHIAETMARGLAYLHEDIPG-L-KDGHKPAISHRDIKSKNVLLKNNLTACIADFGLALKF------EAGKSA--THG---QVGTRRYMAPEVLEGAINFQ--RDAFLRIDMYAMGLVLWELASRCTA--ADGPVDEYMLPFEEEIGQHPSLEDMQEVVVHKKKRPVLRDYWQKHA-GMAMLCETIEECWDHDAEARLSAGCVGERITQMQRL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3 PsiBlast_PDB 88.5242% -72 - C1 -4ASX AVR2A_HUMAN A:[26-316] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LQLLEVKARGRFGCVWKAQLLNEYVAVKIFPIQDKQSWQNEYEVYSLPGMKHENILQFIGAEKRGTSVD-VDLWLITAFHEKGSLSDFLKANVVSWNELCHIAETMARGLAYLHEDIPG-L-KDGHKPAISHRDIKSKNVLLKNNLTACIADFGLALKF------EAGKSAG-THG---QVGTRRYMAPEVLEGAINFQ--RDAFLRIDMYAMGLVLWELASRCTA--ADGPVDEYMLPFEEEIGQHPSLEDMQEVVVHKKKRPVLRDYWQKHA-GMAMLCETIEECWDHDAEARLSAGCVGERITQMQRLT--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4 PsiBlast_PDB 88.4041% -71 - C1 -2QLU AVR2B_HUMAN A:[16-306] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SLQLLEIKARGRFGCVWKAQLMNDFVAVKIFPLQDKQSWQSEREIFSTPGMKHENLLQFIAAEKR-GSNLEVELWLITAFHDKGSLTDYLKGNIITWNELCHVAETMSRGLSYLHEDVPWCR-GEGHKPSIAHRDFKSKNVLLKSDLTAVLADFGLAVRF------EPGKPPGDTHG---QVGTRRYMAPEVLEGAINFQ--RDAFLRIDMYAMGLVLWELVSRCKA--ADGPVDEYMLPFEEEIGQHPSLEELQEVVVHKKMRPTIKDHWLKHP-GLAQLCVTIEECWDHDAEARLSAGCVEERVSLIRRS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
92 HHSearch 88.2943% -71 - C1 -3SOC AVR2A_HUMAN A:[18-320] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NLYFQSMPLQLLEVKARGRFGCVWKAQLLNEYVAVKIFPIQDKQSWQNEYEVYSLPGMKHENILQFIGAEKRGT-SVDVDLWLITAFHEKGSLSDFLKANVVSWNELCHIAETMARGLAYLHEDIP--GLKDGHKPAISHRDIKSKNVLLKNNLTACIADFGLALKFEAGKSA------GDTHG---QVGTRRYMAPEVLEGAINFQ--RDAFLRIDMYAMGLVLWELASRCTA-ADGP-VDEYMLPFEEEIGQHPSLEDMQEVVVHKKKRPVLRDYWQKHA-GMAMLCETIEECWDHDAEARLSAGCVGERITQMQRLT--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19 PsiBlast_PDB 88.2937% -78 - C1 -3TZM TGFR1_HUMAN A:[13-301] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTW-TQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTASGLAHLHMEIV----GTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVR-------HDSATDTIDIAP--RVGTKRYMAPEVLDDSINMKHFES-FKRADIYAMGLVFWEIARRCS---IGGIHEDYQLPYYDLVPSDPSVEEMRKVVCEQKLRPNIPNRW-QSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQLS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21 PsiBlast_CBE 88.0142% -68 - C1 -4ASX AVR2A_HUMAN B:[26-316] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LQLLEVKARGRFGCVWKAQLLNEYVAVKIFPIQDKQSWQNEYEVYSLPGMKHENILQFIGAEKRGTSVD-VDLWLITAFHEKGSLSDFLKANVVSWNELCHIAETMARGLAYLHEDIPG-L-KDGHKPAISHRDIKSKNVLLKNNLTACIADFGLALKF------EAGKSAGDTHG---QVGTRRYMAPEVLEGAINFQ--RDAFLRIDMYAMGLVLWELASRCTA--ADGPVDEYMLPFEEEIGQHPSLEDMQEVVVHKKKRPVLRDYWQKHA-GMAMLCETIEECWDHDAEARLSAGCVGERITQMQRLT--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
94 HHSearch 87.8238% -82 - C1 -3MDY BMR1B_HUMAN A:[37-333] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KQIQMVKQIGKGRYGEVWMGKWRGEKVAVKVFFTTEEASWFRETEIYQTVLMRHENILGFIAADIKGT-GSWTQLYLITDYHENGSLYDYLKSTTLDAKSMLKLAYSSVSGLCHLHTEIF--S--TQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVKFI-------------PNT---RVGTKRYMPPEVLDESLNRNHFQSY-IMADMYSFGLILWEVARRC---VSGGIVEEYQLPYHDLVPSDPSYEDMREIVCIKKLRPSFPNRWSSD-ECLRQMGKLMTECWAHNPASRLTALRVKKTLAKMSESQDIKL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
53 PsiBlast_CBE 87.2838% -72 - C1 -3HMM TGFR1_HUMAN A:[7-295] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTW-TQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTASGLAHLHMEIV----GTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSA----TDTIDIA--------GTKRYMAPEVLDDSINMKHFES-FKRADIYAMGLVFWEIARRCS---IGGIHEDYQLPYYDLVPSDPSVEEMRKVVCEQKLRPNIPNRW-QSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQLSQQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24 PsiBlast_CBE 87.2538% -78 - C1 -3MDY BMR1B_HUMAN C:[38-329] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QIQMVKQIGKGRYGEVWMGKWRGEKVAVKVFFTTEEASWFRETEIYQTVLMRHENILGFIAADIKGTGSWTQLY-LITDYHENGSLYDYLKSTTLDAKSMLKLAYSSVSGLCHLHTEI---F-STQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVKFI-----------IPPNT---RVGTKRYMPPEVLDESLNRNHFQSYI-MADMYSFGLILWEVARRCVS---GGIVEEYQLPYHDLVPSDPSYEDMREIVCIKKLRPSFPNRWSSDE-CLRQMGKLMTECWAHNPASRLTALRVKKTLAKMSESQDI------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20 PsiBlast_PDB 86.9738% -74 - C1 -4X2G ? A:[9-297] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTW-TQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTASGLAHLHMEIV----GTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSA----TDTIDIAPNH---RVGTKRYMAPEVLDDSINMKHFES-FKRADIYAMGLVFWEIARRCS---IGGIHEDYQLPYYDLVPSDPSVEEMRKVVCEQKLRPNIPNRW-QSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQLSQQEGI------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1 PsiBlast_PDB 86.8842% -68 - C1 -3Q4T AVR2A_HUMAN A:[26-316] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LQLLEVKARGRFGCVWKAQLLNEYVAVKIFPIQDKQSWQNEYEVYSLPGMKHENILQFIGAEKRGTSVD-VDLWLITAFHEKGSLSDFLKANVVSWNELCHIAETMARGLAYLHEDIPG-L-KDGHKPAISHRDIKSKNVLLKNNLTACIADFGLALKF------EAGKSAGDTHG---QVGTRRYMAPEVLEGAINFQ--RDAFLRIDMYAMGLVLWELASRCTA--ADGPVDEYMLPFEEEIGQHPSLEDMQEVVVHKKKRPVLRDYWQKHA-GMAMLCETIEECWDHDAEARLSAGCVGERITQMQR----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
50 PsiBlast_CBE 86.7738% -73 - C1 -4X2J TGFR1_HUMAN A:[9-297] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTW-TQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTASGLAHLHMEIV----GTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSA----TDTIDIAPNH---RVGTKRYMAPEVLDDSINMKHFES-FKRADIYAMGLVFWEIARRCS---IGGIHEDYQLPYYDLVPSDPSVEEMRKVVCEQKLRPNIPNRW-QSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQLSQQEGI------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
49 PsiBlast_CBE 86.7738% -73 - C1 -4X2K TGFR1_HUMAN A:[9-297] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTW-TQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTASGLAHLHMEIV----GTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSA----TDTIDIAPNH---RVGTKRYMAPEVLDDSINMKHFES-FKRADIYAMGLVFWEIARRCS---IGGIHEDYQLPYYDLVPSDPSVEEMRKVVCEQKLRPNIPNRW-QSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQLSQQEGI------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
51 PsiBlast_CBE 86.6438% -74 - C1 -4X0M TGFR1_HUMAN A:[9-297] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTW-TQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTASGLAHLHMEIV----GTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSA----TDTIDIAPNH---RVGTKRYMAPEVLDDSINMKHFES-FKRADIYAMGLVFWEIARRCS---IGGIHEDYQLPYYDLVPSDPSVEEMRKVVCEQKLRPNIPNRW-QSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQLSQQEGI------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
55 PsiBlast_CBE 86.4337% -77 - C1 -2WOU TGFR1_HUMAN A:[10-298] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTW-TQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTASGLAHLHMEIV----GTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVR-------HDSATDTIDIAPNHRVGTKRYMAPEVLDDSINMKHFES-FKRADIYAMGLVFWEIARRCS---IGGIHEDYQLPYYDLVPSDPSVEEMRKVVCEQKLRPNIPNRW-QSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQLS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
56 PsiBlast_CBE 85.3437% -74 - C1 -2WOT TGFR1_HUMAN A:[10-298] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTW-TQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTASGLAHLHMEIV----GTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVR-------HDSATDTIDIAPNHRVGTKRYMAPEVLDDSINMKHFES-FKRADIYAMGLVFWEIARRCS---IGGIHEDYQLPYYDLVPSDPSVEEMRKVVCEQKLRPNIPNRW-QSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQLSQQEG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
52 PsiBlast_CBE 85.2838% -70 - C1 -1RW8 TGFR1_HUMAN A:[8-296] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTW-TQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTASGLAHLHMEIV----GTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSA----TDTIDIAPNH---RVGTKRYMAPEVLDDSINMKHFES-FKRADIYAMGLVFWEIARRCS---IGGIHEDYQLPYYDLVPSDPSVEEMRKVVCEQKLRPNIPNRW-QSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQLSQQEG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2 PsiBlast_PDB 84.7642% -68 - C1 -3SOC AVR2A_HUMAN A:[26-316] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LQLLEVKARGRFGCVWKAQLLNEYVAVKIFPIQDKQSWQNEYEVYSLPGMKHENILQFIGAEKRGTSVD-VDLWLITAFHEKGSLSDFLKANVVSWNELCHIAETMARGLAYLHEDIPG-L-KDGHKPAISHRDIKSKNVLLKNNLTACIADFGLALKF------EAGKSAGDTHG---QVGTRRYMAPEVLEGAINFQ--RDAFLRIDMYAMGLVLWELASRCTA--ADGPVDEYMLPFEEEIGQHPSLEDMQEVVVHKKKRPVLRDYWQKHA-GMAMLCETIEECWDHDAEARLSAGCVGERITQMQRLT--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15 PsiBlast_PDB 84.5937% -72 - C1 -1PY5 TGFR1_HUMAN A:[33-321] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTW-TQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTASGLAHLHMEIV----GTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVR-------HDSATDTIDIAPNHRVGTKRYMAPEVLDDSINMKHFES-FKRADIYAMGLVFWEIARRCS---IGGIHEDYQLPYYDLVPSDPSVEEMRKVVCEQKLRPNIPNRW-QSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQLSQQEG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8 PsiBlast_PDB 84.4439% -82 - C1 -3H9R ACVR1_HUMAN A:[39-319] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ITLLECVGKGRYGEVWRGSWQGENVAVKIFSSRDEKSWFRETELYNTVMLRHENILGFIASD-MTS---STQLWLITHYHEMGSLYDYLQLTTLDTVSCLRIVLSIASGLAHLHIEI---F-GTQGKPAIAHRDLKSKNILVKKNGQCCIADLGLAVMH--------------------RVGTKRYMAPEVLDETIQV-DCFDSYKRVDIWAFGLVLWEVARR---MVSNGIVEDYKPPFYDVVPNDPSFEDMRKVVCVDQQRPNIPNRWFSDP-TLTSLAKLMKECWYQNPSARLTALRIKKTLTKID-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30 PsiBlast_CBE 83.7738% -75 - C1 -3Q4U ACVR1_HUMAN B:[9-290] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DITLLECVGKGRYGEVWRGSWQGENVAVKIFSSRDEKSWFRETELYNTVMLRHENILGFIASD-MTSRHSSTQLWLITHYHEMGSLYDYLQLTTLDTVSCLRIVLSIASGLAHLHIEI---F-GTQGKPAIAHRDLKSKNILVKKNGQCCIADLGLAVMHSQS----TNQLDVGNNP---RVGTKRYMAPEVLDETIQV-DCFDSYKRVDIWAFGLVLWEVARR---MVSNGIVEDYKPPFYDVVPNDPSFEDMRKVVCVDQQRPNIPNRWFSDP-TLTSLAKLMKECWYQNPSARLTALRIKKTLTKI------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
93 HHSearch 83.5939% -71 - C1 -3Q4U ACVR1_HUMAN A:[7-300] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ARDITLLECVGKGRYGEVWRGSWQGENVAVKIFSSRDEKSWFRETELYNTVMLRHENILGFIASDMTS-RHSSTQLWLITHYHEMGSLYDYLQLTTLDTVSCLRIVLSIASGLAHLHIEIF----GTQGKPAIAHRDLKSKNILVKKNGQCCIADLGLAVMHSQSTNQ----LDVGNNP---RVGTKRYMAPEVLDETIQV-DCFDSYKRVDIWAFGLVLWEVARRM---VSNGIVEDYKPPFYDVVPNDPSFEDMRKVVCVDQQRPNIPNRWFSDP-TLTSLAKLMKECWYQNPSARLTALRIKKTLTKID-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
54 PsiBlast_CBE 82.5238% -70 - C1 -3GXL TGFR1_HUMAN A:[7-295] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LQESIGKGRFGEVWRGKW---EVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTW-TQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTASGLAHLHMEIV----GTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSA----TDTID--------RVGTKRYMAPEVLDDSINMKHFES-FKRADIYAMGLVFWEIARRCS---I---HEDYQLPYYDLVPSDPSVEEMRKVVCEQKLRPNIPNR---SCEALRVMAKIMRECWYANGAARLTALRIKKTLSQLSQQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27 PsiBlast_CBE 81.8138% -71 - C1 -4BGG ACVR1_HUMAN B:[9-290] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DITLLECVGKGRYGEVWRGSWQGENVAVKIFSSRDEKSWFRETELYNTVMLRHENILGFIASD-MTSRHSSTQLWLITHYHEMGSLYDYLQLTTLDTVSCLRIVLSIASGLAHLHIEI---F-G---KPAIAHRDLKSKNILVKKNGQCCIADLGLAVMHSQS----TNQLDVGNNP---RVGTKRYMAPEVLDETIQV-DCFDSYKRVDIWAFGLVLWEVARR---MVSNGIVEDYKPPFYDVVPNDPSFEDMRKVVCVDQQRPNIPNRWFSDP-TLTSLAKLMKECWYQNPSARLTALRIKKTLTKI------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------