@TOME V2.3
(Nov 2016)

Ref. - - Doc.
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Alignment:

3D Common Core:

Structural Clustering:

Modeller Result :

Complexes Modeling
Templates Information:
Sequence & Result Tab:

Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : CD11B_HUMAN: (2015-10-04 )
MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKRRHRSHSAEGGKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPGEARPARAQKPAQLKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMFPTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGASAAGPGFSLKF

Atome Classification :

(67 SA) .........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450......--.460.......470.......480.......490.......500....---...510.......520.......530--.-......-.540.......550.......560.......570--.........580.......590........600.......610.......620.......630.-......640.----......650.......660.......670..--.....680--......---..690.......700.......710.......720......-.730.......740.......750.......760.......770.......780.......790...
(Atome) (Ident) (Tito) (Num) (Ligand) (Uniprot) MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKRRHRSHSAEGGKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPGEARPARAQKPAQLKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDK--KTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVG---SNMDKIYIVMNYVEHDLKSLMETMK---Q-PFLPGE-VKTLMIQLLRGVKHLHDNWILHRDLKTSNLLL----SHAGILKVGDFGLAREYGSP-LKAYTPVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIFGELLT-QKPLFPGKSE----IDQINKVFKDLGTPSEKIWPGYSELPAVKKM--TFSEHP-Y--NNLRKR---FGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPL-PIDPSMFPTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGASAAGPGFSLKF
100 PsiBlast_CBE 92.5044% -99 - C1 -2UZN CDK2_HUMAN A:[1-293] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MENFQKVEKIGEGTYGVVYKARNK--LTGEVVALKKI---------PSTAIREISLLKELNHPNIVKLLDVIHT---EN--KLYLVFEFLHQDLKKFMDASA---L-TGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTEGAIKLADFGLARAF-----------VVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSE----IDQLFRIFRTLGTPDEVVWPGVTSMPDYKP---SFPKWA-R--QDFSKV---VPP-LDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTK-PVPHLRL------------------------------------------------------------
98 PsiBlast_CBE 91.8244% -92 - C1 -2V0D CDK2_HUMAN A:[1-293] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MENFQKVEKIGEGTYGVVYKARNK--LTGEVVALKKIRL------VPSTAIREISLLKELNHPNIVKLLDVIHT---EN--KLYLVFEFLHQDLKKFMDASA---L-TGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTEGAIKLADFGLARAFGVP-VRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSE----IDQLFRIFRTLGTPDEVVWPGVTSMPDYKP---SFPKWA-R--QDFSKV---VPP-LDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTK-PVPHLRL------------------------------------------------------------
63 PsiBlast_CBE 91.7944% -93 - C1 -3LFQ CDK2_HUMAN A:[1-293] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MENFQKVEKIGEGTYGVVYKARNK--LTGEVVALKKIR---------STAIREISLLKELNHPNIVKLLDVIHT---EN--KLYLVFEFLHQDLKKFMDASA---L-TGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTEGAIKLADFGLARAFGVP-VRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSE----IDQLFRIFRTLGTPDEVVWPGVTSMPDYKP---SFPKWA-R--QDFSKV---VPP-LDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTK-PVPHLRL------------------------------------------------------------
88 PsiBlast_CBE 91.6844% -96 - C1 -2VTQ CDK2_HUMAN A:[1-293] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MENFQKVEKIGEGTYGVVYKARNK--LTGEVVALKKIR---------STAIREISLLKELNHPNIVKLLDVIHT---EN--KLYLVFEFLHQDLKKFMDASA---L-TGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTEGAIKLADFG----------------VVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSE----IDQLFRIFRTLGTPDEVVWPGVTSMPDYKP---SFPKWA-R--QDFSKV---VPP-LDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTK-PVPHLRL------------------------------------------------------------
61 PsiBlast_CBE 91.6744% -93 - C1 -3NS9 CDK2_HUMAN A:[3-293] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NFQKVEKIGEGTYGVVYKARNK--LTGEVVALKKI-------GVPSTAIREISLLKELNHPNIVKLLDVIHT---EN--KLYLVFEFLHQDLKKFMDASA---L-TGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTEGAIKLADFGLARAFGVP-VRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSE----IDQLFRIFRTLGTPDEVVWPGVTSMPDYKP---SFPKWA-R--QDFSKV---VPP-LDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTK-PVPHLRL------------------------------------------------------------
51 PsiBlast_CBE 91.6244% -93 - C1 -3WBL CDK2_HUMAN A:[1-293] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MENFQKVEKIGEGTYGVVYKARNK---TGEVVALKKIRL-----GVPSTAIREISLLKELNHPNIVKLLDVIHT---EN--KLYLVFEFLHQDLKKFMDASA---L-TGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTEGAIKLADFGLARAFG----------VVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSE----IDQLFRIFRTLGTPDEVVWPGVTSMPDYKP---SFPKWA-R--QDFSKV---VPP-LDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTK-PVPHLRL------------------------------------------------------------
92 PsiBlast_CBE 91.5244% -94 - C1 -2VTM CDK2_HUMAN A:[1-293] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MENFQKVEKIGEGTYGVVYKARNK--LTGEVVALKKI--------VPSTAIREISLLKELNHPNIVKLLDVIHT---EN--KLYLVFEFLHQDLKKFMDASA---L-TGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTEGAIKLADFGLARAFGVP-VRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSE----IDQLFRIFRTLGTPDEVVWPGVTSMPDYKP---SFPKWA-R--QDFSKV---VPP-LDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTK-PVPHLRL------------------------------------------------------------
50 PsiBlast_CBE 91.5144% -99 - C1 -4BGH CDK2_HUMAN A:[1-293] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MENFQKVEKIGEGTYGVVYKARNK--LTGEVVALKKI---------PSTAIREISLLKELNHPNIVKLLDVIHT---EN--KLYLVFEFLHQDLKKFMDASA---L-TGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTEGAIKLADFGLA---------------VTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSE----IDQLFRIFRTLGTPDEVVWPGVTSMPDYKP---SFPKWA-R--QDFSKV---VPP-LDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTK-PVPHLRL------------------------------------------------------------
90 PsiBlast_CBE 91.5044% -94 - C1 -2VTO CDK2_HUMAN A:[1-293] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MENFQKVEKIGEGTYGVVYKARNK--LTGEVVALKKIR-------VPSTAIREISLLKELNHPNIVKLLDVIHT---EN--KLYLVFEFLHQDLKKFMDASA---L-TGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTEGAIKLADFGLARAF---------HEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSE----IDQLFRIFRTLGTPDEVVWPGVTSMPDYKP---SFPKWA-R--QDFSKV---VPP-LDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTK-PVPHLRL------------------------------------------------------------
94 PsiBlast_CBE 91.2744% -97 - C1 -2VTJ CDK2_HUMAN A:[1-293] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MENFQKVEKIGEGTYGVVYKARNK--LTGEVVALKKIR---------STAIREISLLKELNHPNIVKLLDVIHT---EN--KLYLVFEFLHQDLKKFMDASA---L-TGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTEGAIKLADFGLAR--------------VTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSE----IDQLFRIFRTLGTPDEVVWPGVTSMPDYKP---SFPKWA-R--QDFSKV---VPP-LDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTK-PVPHLRL------------------------------------------------------------
95 PsiBlast_CBE 91.2144% -96 - C1 -2VTI CDK2_HUMAN A:[1-293] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MENFQKVEKIGEGTYGVVYKARNK--LTGEVVALKKI--------VPSTAIREISLLKELNHPNIVKLLDVIHT---EN--KLYLVFEFLHQDLKKFMDASA---L-TGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTEGAIKLADFGLARAF-----------VVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSE----IDQLFRIFRTLGTPDEVVWPGVTSMPDYKP---SFPKWA-R--QDFSKV---VPP-LDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTK-PVPHLRL------------------------------------------------------------
67 PsiBlast_CBE 91.1744% -94 - C1 -3FZ1 CDK2_HUMAN A:[1-293] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MENFQKVEKIGEGTYGVVYKARNK--LTGEVVALKKIR-------VPSTAIREISLLKELNHPNIVKLLDVIHT---EN--KLYLVFEFLHQDLKKFMDASA---L-TGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTEGAIKLADFGLARAFG--------HEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSE----IDQLFRIFRTLGTPDEVVWPGVTSMPDYKP---SFPKWA-R--QDFSKV---VPP-LDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTK-PVPHLRL------------------------------------------------------------
64 PsiBlast_CBE 90.9844% -93 - C1 -3LFN CDK2_HUMAN A:[1-293] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MENFQKVEKIGEGTYGVVYKARNK--LTGEVVALKKIR----TEGVPSTAIREISLLKELNHPNIVKLLDVIHT---EN--KLYLVFEFLHQDLKKFMDASA---L-TGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTEGAIKLADFGLARA----------HEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSE----IDQLFRIFRTLGTPDEVVWPGVTSMPDYKP---SFPKWA-R--QDFSKV---VPP-LDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTK-PVPHLRL------------------------------------------------------------
49 PsiBlast_CBE 90.9544% -98 - C1 -4BZD CDK2_HUMAN A:[2-294] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MENFQKVEKIGEG-YGVVYKARNK--LTGEVVALKKIRL------VPSTAIREISLLKELNHPNIVKLLDVIHT---EN--KLYLVFEFLHQDLKKFMDASA---L-TGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTEGAIKLADFGL---------------VVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSE----IDQLFRIFRTLGTPDEVVWPGVTSMPDYKP---SFPKWA-R--QDFSKV---VPP-LDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTK-PVPHLRL------------------------------------------------------------
57 PsiBlast_CBE 90.8944% -93 - C1 -3TI1 CDK2_HUMAN A:[1-293] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MENFQKVEKIGEGTYGVVYKARNK--LTGEVVALKKIR----TEGVPSTAIREISLLKELNHPNIVKLLDVIHT---EN--KLYLVFEFLHQDLKKFMDASA---L-TGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTEGAIKLADFGLARAFGVP-VRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSE----IDQLFRIFRTLGTPDEVVWPGVTSMPDYKP---SFPKWA-R--QDFSKV---VPP-LDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTK-PVPHLRL------------------------------------------------------------
74 PsiBlast_CBE 90.8344% -89 - C1 -2XNB CDK2_HUMAN A:[1-293] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MENFQKVEKIGEGTYGVVYKARNK--LTGEVVALKKIRLD--TEGVPSTAIREISLLKELNHPNIVKLLDVIHT---EN--KLYLVFEFLHQDLKKFMDASA---L-TGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTEGAIKLADFGLARAFGVP-VRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSE----IDQLFRIFRTLGTPDEVVWPGVTSMPDYKP---SFPKWA-R--QDFSKV---VPP-LDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTK-PVPHLRL------------------------------------------------------------
48 PsiBlast_CBE 90.8344% -96 - C1 -4D1X CDK2_HUMAN A:[3-293] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NFQKVEKIGEGTYGVVYKARNK--LTGEVVALKKI-----------TAIREISLLKELNHPNIVKLLDVIHT---EN--KLYLVFEFLHQDLKKFMDASA---L-TGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTEGAIKLADFGLARAFG------------TLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSE----IDQLFRIFRTLGTPDEVVWPGVTSMPDYKP---SFPKWA-R--QDFSKV---VPP-LDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTK-PVPHLRL------------------------------------------------------------
97 PsiBlast_CBE 90.7944% -90 - C1 -2VTA CDK2_HUMAN A:[1-293] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MENFQKVEKIGEGTYGVVYKARNK--LTGEVVALKKIR---------STAIREISLLKELNHPNIVKLLDVIHT---EN--KLYLVFEFLHQDLKKFMDASA---L-TGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTEGAIKLADFGLARAF------------VTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSE----IDQLFRIFRTLGTPDEVVWPGVTSMPDYKP---SFPKWA-R--QDFSKV---VPP-LDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTK-PVPHLRL------------------------------------------------------------
93 PsiBlast_CBE 90.7044% -93 - C1 -2VTL CDK2_HUMAN A:[1-293] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MENFQKVEKIGEGTYGVVYKARNK--LTGEVVALKKI--------VPSTAIREISLLKELNHPNIVKLLDVIHT---EN--KLYLVFEFLHQDLKKFMDASA---L-TGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTEGAIKLADFGLARAFGVP-VRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSE----IDQLFRIFRTLGTPDEVVWPGVTSMPDYKP---SFPKWA-R--QDFSKV---VPP-LDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTK-PVPHLRL------------------------------------------------------------
99 PsiBlast_CBE 90.6144% -93 - C1 -2UZO CDK2_HUMAN A:[1-293] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MENFQKVEKIGEGTYGVVYKARNK--LTGEVVALKKIRL------VPSTAIREISLLKELNHPNIVKLLDVIHT---EN--KLYLVFEFLHQDLKKFMDASA---L-TGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTEGAIKLADFGLARAFGVP-VRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSE----IDQLFRIFRTLGTPDEVVWPGVTSMPDYKP---SFPKWA-R--QDFSKV---VPP-LDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTK-PVPHL--------------------------------------------------------------
96 PsiBlast_CBE 90.6044% -95 - C1 -2VTH CDK2_HUMAN A:[1-293] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MENFQKVEKIGEGTYGVVYKARNK--LTGEVVALKKIR---------STAIREISLLKELNHPNIVKLLDVIHT---EN--KLYLVFEFLHQDLKKFMDASA---L-TGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTEGAIKLADFGLARAF------------VTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSE----IDQLFRIFRTLGTPDEVVWPGVTSMPDYKP---SFPKWA-R--QDFSKV---VPP-LDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTK-PVPHLRL------------------------------------------------------------
62 PsiBlast_CBE 90.5844% -92 - C1 -3LFS CDK2_HUMAN A:[1-293] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MENFQKVEKIGEGTYGVVYKARNK--LTGEVVALKKIR--------PSTAIREISLLKELNHPNIVKLLDVIHT---EN--KLYLVFEFLHQDLKKFMDASA---L-TGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTEGAIKLADFGLARAFGVP-VRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSE----IDQLFRIFRTLGTPDEVVWPGVTSMPDYKP---SFPKWA-R--QDFSKV---VPP-LDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTK-PVPHLRL------------------------------------------------------------
75 PsiBlast_CBE 90.5644% -92 - C1 -2XMY CDK2_HUMAN A:[1-293] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MENFQKVEKIGEGTYGVVYKARNK--LTGEVVALKKIRLDT---GVPSTAIREISLLKELNHPNIVKLLDVIHT---EN--KLYLVFEFLHQDLKKFMDASA---L-TGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTEGAIKLADFGLARAFGVP-VRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSE----IDQLFRIFRTLGTPDEVVWPGVTSMPDYKP---SFPKWA-R--QDFSKV---VPP-LDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTK-PVPHLRL------------------------------------------------------------
87 PsiBlast_CBE 90.5144% -90 - C1 -2VTR CDK2_HUMAN A:[1-293] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MENFQKVEKIGEGTYGVVYKARNK--LTGEVVALKKIR--------PSTAIREISLLKELNHPNIVKLLDVIHT---EN--KLYLVFEFLHQDLKKFMDASA---L-TGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTEGAIKLADFGLARAFGVP-VRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSE----IDQLFRIFRTLGTPDEVVWPGVTSMPDYKP---SFPKWA-R--QDFSKV---VPP-LDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTK-PVPHLRL------------------------------------------------------------
82 PsiBlast_CBE 90.4344% -96 - C1 -2W06 CDK2_HUMAN A:[1-293] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MENFQKVEKIGEGTYGVVYKARNK--LTGEVVALKKIR-------VPSTAIREISLLKELNHPNIVKLLDVIHT---EN--KLYLVFEFLHQDLKKFMDASA---L-TGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTEGAIKLADFGLARAF----------EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSE----IDQLFRIFRTLGTPDEVVWPGVTSMPDYKP---SFPKWA-R--QDFSKV---VPP-LDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTK-PVPHLRL------------------------------------------------------------
73 PsiBlast_CBE 90.4344% -91 - C1 -3EID CDK2_HUMAN A:[1-293] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MENFQKVEKIGEGTYGVVYKARNK--LTGEVVALKKIRL---TEGVPSTAIREISLLKELNHPNIVKLLDVIHT---EN--KLYLVFEFLHQDLKKFMDASA---L-TGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTEGAIKLADFGLARAFGVP-VRTYT--VVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSE----IDQLFRIFRTLGTPDEVVWPGVTSMPDYKP---SFPKWA-R--QDFSKV---VPP-LDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTK-PVPHLR-------------------------------------------------------------
86 PsiBlast_CBE 90.3344% -93 - C1 -2VTS CDK2_HUMAN A:[1-293] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MENFQKVEKIGEGTYGVVYKARNK--LTGEVVALKKIR--------PSTAIREISLLKELNHPNIVKLLDVIHT---EN--KLYLVFEFLHQDLKKFMDASA---L-TGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTEGAIKLADFGLARAF---------HEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSE----IDQLFRIFRTLGTPDEVVWPGVTSMPDYKP---SFPKWA-R--QDFSKV---VPP-LDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTK-PVPHLRL------------------------------------------------------------
71 PsiBlast_CBE 90.3344% -90 - C1 -3EJ1 CDK2_HUMAN C:[1-293] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MENFQKVEKIGEGTYGVVYKARNK--LTGEVVALKKIRL---TEGVPSTAIREISLLKELNHPNIVKLLDVIHT---EN--KLYLVFEFLHQDLKKFMDASA---L-TGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTEGAIKLADFGLARAFGVP-VRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSE----IDQLFRIFRTLGTPDEVVWPGVTSMPDYKP---SFPKWA-R--QDFSKV---VPP-LDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTK-PVPHLR-------------------------------------------------------------
52 PsiBlast_CBE 90.1444% -91 - C1 -3UNK CDK2_HUMAN A:[1-293] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MENFQKVEKIGEGTYGVVYKARNK--LTGEVVALKKIR---ETEGVPSTAIREISLLKELNHPNIVKLLDVIHT---EN--KLYLVFEFLHQDLKKFMDASA---L-TGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTEGAIKLADFGLARAFGVP-VRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSE----IDQLFRIFRTLGTPDEVVWPGVTSMPDYKP---SFPKWA-R--QDFSKV---VPP-LDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTK-PVPHLRL------------------------------------------------------------
55 PsiBlast_CBE 90.0444% -92 - C1 -3TIZ CDK2_HUMAN A:[2-293] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ENFQKVEKIGEGTYGVVYKARNK--LTGEVVALKKIR----TEGVPSTAIREISLLKELNHPNIVKLLDVIHT---EN--KLYLVFEFLHQDLKKFMDASA---L-TGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTEGAIKLADFGLARAFGVP-VRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSE----IDQLFRIFRTLGTPDEVVWPGVTSMPDYKP---SFPKWA-R--QDFSKV---VPP-LDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTK-PVPHLRL------------------------------------------------------------
56 PsiBlast_CBE 90.0144% -91 - C1 -3TIY CDK2_HUMAN A:[2-293] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ENFQKVEKIGEGTYGVVYKARNK--LTGEVVALKKIR----TEGVPSTAIREISLLKELNHPNIVKLLDVIHT---EN--KLYLVFEFLHQDLKKFMDASA---L-TGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTEGAIKLADFGLARAFGVP-VRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSE----IDQLFRIFRTLGTPDEVVWPGVTSMPDYKP---SFPKWA-R--QDFSKV---VPP-LDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTK-PVPHLRL------------------------------------------------------------
85 PsiBlast_CBE 90.0044% -94 - C1 -2VU3 CDK2_HUMAN A:[1-293] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MENFQKVEKIGEGTYGVVYKARNK--LTGEVVALKKIRL---------TAIREISLLKELNHPNIVKLLDVIHT---EN--KLYLVFEFLHQDLKKFMDASA---L-TGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTEGAIKLADFG----FGVP-VRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSE----IDQLFRIFRTLGTPDEVVWPGVTSMPDYKP---SFPKWA-R--QDFSKV---VPP-LDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTK-PVPHLRL------------------------------------------------------------
60 PsiBlast_CBE 89.9344% -97 - C1 -3S2P CDK2_HUMAN A:[1-293] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MENFQKVEKIGEGTYGVVYKARNK--LTGEVVALKKI--------VPSTAIREISLLKELNHPNIVKLLDVIHT---EN--KLYLVFEFLHQDLKKFMDASA---L-TGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTEGAIKLADFGLARAF------------VTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSE----IDQLFRIFRTLGTPDEVVWPGVTSMPDYKP---SFPKWA-R--QDFSKV---VPP-LDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTK-PVPHLRL------------------------------------------------------------
80 PsiBlast_CBE 89.9144% -90 - C1 -2W1H CDK2_HUMAN A:[1-293] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MENFQKVEKIGEGTYGVVYKARNK--LTGEVVALKKIR----TEGVPSTAIREISLLKELNHPNIVKLLDVIHT---EN--KLYLVFEFLHQDLKKFMDASA---L-TGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTEGAIKLADFGLARAF------------VTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSE----IDQLFRIFRTLGTPDEVVWPGVTSMPDYKP---SFPKWA-R--QDFSKV---VPP-LDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTK-PVPHLRL------------------------------------------------------------
91 PsiBlast_CBE 89.8544% -91 - C1 -2VTN CDK2_HUMAN A:[1-293] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MENFQKVEKIGEGTYGVVYKARNK--LTGEVVALKKIR--------PSTAIREISLLKELNHPNIVKLLDVIHT---EN--KLYLVFEFLHQDLKKFMDASA---L-TGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTEGAIKLADFG-----------------VTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSE----IDQLFRIFRTLGTPDEVVWPGVTSMPDYKP---SFPKWA-R--QDFSKV---VPP-LDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTK-PVPHLRL------------------------------------------------------------
89 PsiBlast_CBE 89.8444% -94 - C1 -2VTP CDK2_HUMAN A:[1-293] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MENFQKVEKIGEGTYGVVYKARNK--LTGEVVALKKI--------VPSTAIREISLLKELNHPNIVKLLDVIHT---EN--KLYLVFEFLHQDLKKFMDASA---L-TGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTEGAIKLADFGLARAF----------EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSE----IDQLFRIFRTLGTPDEVVWPGVTSMPDYKP---SFPKWA-R--QDFSKV---VPP-LDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTK-PVPHLRL------------------------------------------------------------
72 PsiBlast_CBE 89.6844% -93 - C1 -3EJ1 CDK2_HUMAN A:[1-293] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MENFQKVEKIGEGTYGVVYKARNK--LTGEVVALKKIRL---TEGVPSTAIREISLLKELNHPNIVKLLDVIHT---EN--KLYLVFEFLHQDLKKFMDASA---L-TGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTEGAIKLADFGLARAFGVP-VRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSE----IDQLFRIFRTLGTPDEVVWPGVTSMPDYKP---SFPKWA-R--QDFSKV---VPP-LDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTK-PVPHLRL------------------------------------------------------------
68 PsiBlast_CBE 89.4444% -86 - C1 -3F5X CDK2_HUMAN C:[1-293] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MENFQKVEKIGEGTYGVVYKARNK--LTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHT---EN--KLYLVFEFLHQDLKKFMDASA---L-TGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLI----NTEGAIKLADFGLARAFGVP-VRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSE----IDQLFRIFRTLGTPDEVVWPGVTSMPDYKP---SFPKWA-R--QDFSKV---VPP-LDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTK-PVPHLRL------------------------------------------------------------