@TOME V2.3
(Nov 2016)

Ref. - - Doc.
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Alignment:

3D Common Core:

Structural Clustering:

Modeller Result :

Complexes Modeling
Templates Information:
Sequence & Result Tab:

Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : CDKL4_HUMAN: (2015-10-05 )
MEKYEKLAKTGEGSYGVVFKCRNKTSGQVVAVKKFVESEDDPVVKKIALREIRMLKQLKHPNLVNLIEVFRRKRKMHLVFEYCDHTLLNELERNPNGVADGVIKSVLWQTLQALNFCHIHNCIHRDIKPENILITKQGIIKICDFGFAQILIPGDAYTDYVATRWYRAPELLVGDTQYGSSVDIWAIGCVFAELLTGQPLWPGKSDVDQLYLIIRTLGKLIPRHQSIFKSNGFFHGISIPEPEDMETLEEKFSDVHPVALNFMKGCLKMNPDDRLTCSQLLESSYFDSFQEAQIKRKARNEGRNRRRQQQAPKSAFPRLFLKTKICQVQRNETQTSGNQILPNGPILQNSMVTVMTNINSAVYQVTVLHLLSENFEVKS

Atome Classification :

(71 SA) .........10........20...-.....30.......-.40........50........60........70..-----......80........90....-....100.......110.......120.......130.......140.......150.-.......160.......170.......180.......190....-...200.......210.......220...-....230-.......-..240-........250.-.....----.260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......
(Atome) (Ident) (Tito) (Num) (Ligand) (Uniprot) MEKYEKLAKTGEGSYGVVFKCRNK-TSGQVVAVKKFVES-EDDPVVKKIALREIRMLKQLKHPNLVNLIEVFRRK-----RKMHLVFEYCDHTLLNELERNP-NGVADGVIKSVLWQTLQALNFCHIHNCIHRDIKPENILITKQGIIKICDFGFAQIL-I-PGDAYTDYVATRWYRAPELLVGDTQYGSSVDIWAIGCVFAELLT-GQPLWPGKSDVDQLYLIIRTLGKLIPRHQ-SIFKS---NGFFHGI-SIPE--PEDMETLEEKFS-DVHPV----ALNFMKGCLKMNPDDRLTCSQLLESSYFDSFQEAQIKRKARNEGRNRRRQQQAPKSAFPRLFLKTKICQVQRNETQTSGNQILPNGPILQNSMVTVMTNINSAVYQVTVLHLLSENFEVKS
111 HHSearch 95.4072%-130 - C1 -4AGU CDKL1_HUMAN A:[3-292] -EKYEKIGKIGEGSYGVVFKCRNR-DTGQIVAIKKFLES-ED-PVIKKIALREIRMLKQLKHPNLVNLLEVFRRK-----RRLHLVFEYCDHTVLHELDRYQ-RGVPEHLVKSITWQTLQAVNFCHKHNCIHRDVKPENILITKHSVIKLCDFGFARLL-T------------RWYRSPELLVGDTQYGPPVDVWAIGCVFAELLS-GVPLWPGKSDVDQLYLIRKTLGDLIPRHQ-QVFST---NQYFSGV-KIPD--PEDMEPLELKFP-NISYP----ALGLLKGCLHMDPTERLTCEQLLHHPYFENIR-----------------------------------------------------------------------------------------
112 HHSearch 84.9555%-133 - C1 -4AAA CDKL2_HUMAN A:[24-314] MEKYENLGLVGEGSYGMVMKCRNK-DTGRIVAIKKFLES-DDDKMVKKIAMREIKLLKQLRHENLVNLLEVCKKK-----KRWYLVFEFVDHTILDDLELFP-NGLDYQVVQKYLFQIINGIGFCHSHNIIHRDIKPENILVSQSGVVKLCDFGFA-------------EVATRWYRAPELLVGDVKYGKAVDVWAIGCLVTEMFM-GEPLFPGDSDIDQLYHIMMCLGNLIPRHQ-ELFNK---NPVFAGV-RLPE--IKEREPLERRYP-KLSEV----VIDLAKKCLHIDPDKRPFCAELLHHDFFQMDGFAERFSQELQL------------------------------------------------------------------------------
114 HHSearch 80.3349%-117 - C1 -3ZDU CDKL3_HUMAN A:[2-290] MEMYETLGKVGEGSYGTVMKCKHK-NTGQIVAIKIFY---------NKIAMREIKFLKQFHHENLVNLIEVFRQK-----KKIHLVFEFIDHTVLDELQHYC-HGLESKRLRKYLFQILRAIDYLHSNNIIHRDIKPENILVSQSGITKLCDFGFART------DIYDDEVATRWYRAPELVLKDTSYGKPVDIWALGCMIIEMAT-GNPYLPSSSDLDLLHKIVLKVGNLSPHLQ-NIFSK---SPIFAGV-VLPQ--VQHPKNARKKYP-KLNGL----LADIVHACLQIDPADRISSSDLLHHEYFTRDGFIEKFMPELKAKLLQEAKV----------------------------------------------------------------------
96 PsiBlast_CBE 78.6640%-127 - C1 -2UZN CDK2_HUMAN A:[1-286] MENFQKVEKIGEGTYGVVYKARNK-LTGEVVALKKI----------PSTAIREISLLKELNHPNIVKLLDVIHTE-----NKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAF-----------VVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSEIDQLFRIFRTLGT----------PD---EVVWPGVTSMPDYKPSFPKWARQDFS-KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL---------------------------------------------------------------------------------
62 PsiBlast_CBE 78.1540%-123 - C1 -3FZ1 CDK2_HUMAN A:[1-286] MENFQKVEKIGEGTYGVVYKARNK-LTGEVVALKKIR--------VPSTAIREISLLKELNHPNIVKLLDVIHTE-----NKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFG--------HEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSEIDQLFRIFRTLGT----------PD---EVVWPGVTSMPDYKPSFPKWARQDFS-KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL---------------------------------------------------------------------------------
92 PsiBlast_CBE 77.7240%-125 - C1 -2VTH CDK2_HUMAN A:[1-286] MENFQKVEKIGEGTYGVVYKARNK-LTGEVVALKKIR----------STAIREISLLKELNHPNIVKLLDVIHTE-----NKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAF------------VTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSEIDQLFRIFRTLGT----------PD---EVVWPGVTSMPDYKPSFPKWARQDFS-KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL---------------------------------------------------------------------------------
82 PsiBlast_CBE 77.3940%-121 - C1 -2VTS CDK2_HUMAN A:[1-286] MENFQKVEKIGEGTYGVVYKARNK-LTGEVVALKKIR---------PSTAIREISLLKELNHPNIVKLLDVIHTE-----NKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAF---------HEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSEIDQLFRIFRTLGT----------PD---EVVWPGVTSMPDYKPSFPKWARQDFS-KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL---------------------------------------------------------------------------------
78 PsiBlast_CBE 77.2140%-124 - C1 -2W06 CDK2_HUMAN A:[1-286] MENFQKVEKIGEGTYGVVYKARNK-LTGEVVALKKIR--------VPSTAIREISLLKELNHPNIVKLLDVIHTE-----NKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAF----------EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSEIDQLFRIFRTLGT----------PD---EVVWPGVTSMPDYKPSFPKWARQDFS-KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL---------------------------------------------------------------------------------
86 PsiBlast_CBE 77.1940%-124 - C1 -2VTO CDK2_HUMAN A:[1-286] MENFQKVEKIGEGTYGVVYKARNK-LTGEVVALKKIR--------VPSTAIREISLLKELNHPNIVKLLDVIHTE-----NKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAF---------HEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSEIDQLFRIFRTLGT----------PD---EVVWPGVTSMPDYKPSFPKWARQDFS-KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL---------------------------------------------------------------------------------
99 PsiBlast_CBE 77.0440%-127 - C1 -2R64 CDK2_HUMAN A:[1-286] MENFQKVEKIGEGTYGVVYKARNK-LTGEVVALKKI---------VPSTAIREISLLKELNHPNIVKLLDVIHTE-----NKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAF------------VTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSEIDQLFRIFRTLGT----------PD---EVVWPGVTSMPDYKPSFPKWARQDFS-KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL---------------------------------------------------------------------------------
95 PsiBlast_CBE 76.8240%-119 - C1 -2UZO CDK2_HUMAN A:[1-286] MENFQKVEKIGEGTYGVVYKARNK-LTGEVVALKKIRL-------VPSTAIREISLLKELNHPNIVKLLDVIHTE-----NKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGV-PVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSEIDQLFRIFRTLGT----------PD---EVVWPGVTSMPDYKPSFPKWARQDFS-KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHL-----------------------------------------------------------------------------------
93 PsiBlast_CBE 76.5940%-122 - C1 -2VTA CDK2_HUMAN A:[1-286] MENFQKVEKIGEGTYGVVYKARNK-LTGEVVALKKIR----------STAIREISLLKELNHPNIVKLLDVIHTE-----NKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAF------------VTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSEIDQLFRIFRTLGT----------PD---EVVWPGVTSMPDYKPSFPKWARQDFS-KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL---------------------------------------------------------------------------------
73 PsiBlast_CBE 76.4140%-112 - C1 -2X1N CDK2_HUMAN A:[1-286] MENFQKVEKIGEGTYGVVYKARNK-LTGEVVALKKIRLD-TETEGVPSTAIREISLLKELNHPNIVKLLDVIHTE-----NKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGV-PVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSEIDQLFRIFRTLGT----------PD---EVVWPGVTSMPDYKPSFPKWARQDFS-KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHL-----------------------------------------------------------------------------------
56 PsiBlast_CBE 76.3340%-123 - C1 -3NS9 CDK2_HUMAN A:[3-286] --NFQKVEKIGEGTYGVVYKARNK-LTGEVVALKKI--------GVPSTAIREISLLKELNHPNIVKLLDVIHTE-----NKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGV-PVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSEIDQLFRIFRTLGT----------PD---EVVWPGVTSMPDYKPSFPKWARQDFS-KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL---------------------------------------------------------------------------------
47 PsiBlast_CBE 76.3240%-118 - C1 -3UNK CDK2_HUMAN A:[1-286] MENFQKVEKIGEGTYGVVYKARNK-LTGEVVALKKIR----ETEGVPSTAIREISLLKELNHPNIVKLLDVIHTE-----NKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGV-PVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSEIDQLFRIFRTLGT----------PD---EVVWPGVTSMPDYKPSFPKWARQDFS-KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL---------------------------------------------------------------------------------
83 PsiBlast_CBE 76.1940%-116 - C1 -2VTR CDK2_HUMAN A:[1-286] MENFQKVEKIGEGTYGVVYKARNK-LTGEVVALKKIR---------PSTAIREISLLKELNHPNIVKLLDVIHTE-----NKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGV-PVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSEIDQLFRIFRTLGT----------PD---EVVWPGVTSMPDYKPSFPKWARQDFS-KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL---------------------------------------------------------------------------------
43 PsiBlast_CBE 76.1940%-127 - C1 -4D1X CDK2_HUMAN A:[3-286] --NFQKVEKIGEGTYGVVYKARNK-LTGEVVALKKI------------TAIREISLLKELNHPNIVKLLDVIHTE-----NKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFG------------TLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSEIDQLFRIFRTLGT----------PD---EVVWPGVTSMPDYKPSFPKWARQDFS-KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL---------------------------------------------------------------------------------
49 PsiBlast_CBE 75.9540%-122 - C1 -3ULI CDK2_HUMAN A:[1-286] MENFQKVEKIGEGTYGVVYKARNK-LTGEVVALKKIRLD------VPSTAIREISLLKELNHPNIVKLLDVIHTE-----NKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGV--------EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSEIDQLFRIFRTLGT----------PD---EVVWPGVTSMPDYKPSFPKWARQDFS-KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL---------------------------------------------------------------------------------
97 PsiBlast_CBE 75.9440%-114 - C1 -2UUE CDK2_HUMAN C:[1-286] MENFQKVEKIGEGTYGVVYKARNK-LTGEVVALKKIRLD-TETEGVPSTAIREISLLKELNHPNIVKLLDVIHTE-----NKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGV-PVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSEIDQLFRIFRTLGT----------PD---EVVWPGVTSMPDYKPSFPKWARQDFS-KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLR----------------------------------------------------------------------------------
59 PsiBlast_CBE 75.8540%-121 - C1 -3LFN CDK2_HUMAN A:[1-286] MENFQKVEKIGEGTYGVVYKARNK-LTGEVVALKKIR-----TEGVPSTAIREISLLKELNHPNIVKLLDVIHTE-----NKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARA----------HEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSEIDQLFRIFRTLGT----------PD---EVVWPGVTSMPDYKPSFPKWARQDFS-KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL---------------------------------------------------------------------------------
46 PsiBlast_CBE 75.7740%-120 - C1 -3WBL CDK2_HUMAN A:[1-286] MENFQKVEKIGEGTYGVVYKARNK--TGEVVALKKIRL------GVPSTAIREISLLKELNHPNIVKLLDVIHTE-----NKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFG----------VVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSEIDQLFRIFRTLGT----------PD---EVVWPGVTSMPDYKPSFPKWARQDFS-KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL---------------------------------------------------------------------------------
90 PsiBlast_CBE 75.7540%-118 - C1 -2VTJ CDK2_HUMAN A:[1-286] MENFQKVEKIGEGTYGVVYKARNK-LTGEVVALKKIR----------STAIREISLLKELNHPNIVKLLDVIHTE-----NKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLAR--------------VTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSEIDQLFRIFRTLGT----------PD---EVVWPGVTSMPDYKPSFPKWARQDFS-KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL---------------------------------------------------------------------------------
94 PsiBlast_CBE 75.6040%-119 - C1 -2V0D CDK2_HUMAN A:[1-286] MENFQKVEKIGEGTYGVVYKARNK-LTGEVVALKKIRL-------VPSTAIREISLLKELNHPNIVKLLDVIHTE-----NKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGV-PVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSEIDQLFRIFRTLGT----------PD---EVVWPGVTSMPDYKPSFPKWARQDFS-KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL---------------------------------------------------------------------------------
79 PsiBlast_CBE 75.4940%-124 - C1 -2W05 CDK2_HUMAN A:[1-286] MENFQKVEKIGEGTYGVVYKARNK-LTGEVVALKKIR----------STAIREISLLKELNHPNIVKLLDVIHTE-----NKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGL--------------EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSEIDQLFRIFRTLGT----------PD---EVVWPGVTSMPDYKPSFPKWARQDFS-KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL---------------------------------------------------------------------------------
89 PsiBlast_CBE 75.4640%-118 - C1 -2VTL CDK2_HUMAN A:[1-286] MENFQKVEKIGEGTYGVVYKARNK-LTGEVVALKKI---------VPSTAIREISLLKELNHPNIVKLLDVIHTE-----NKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGV-PVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSEIDQLFRIFRTLGT----------PD---EVVWPGVTSMPDYKPSFPKWARQDFS-KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL---------------------------------------------------------------------------------
58 PsiBlast_CBE 75.4440%-125 - C1 -3LFQ CDK2_HUMAN A:[1-286] MENFQKVEKIGEGTYGVVYKARNK-LTGEVVALKKIR----------STAIREISLLKELNHPNIVKLLDVIHTE-----NKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGV-PVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSEIDQLFRIFRTLGT----------PD---EVVWPGVTSMPDYKPSFPKWARQDFS-KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL---------------------------------------------------------------------------------
44 PsiBlast_CBE 75.2640%-117 - C1 -4BZD CDK2_HUMAN A:[2-287] MENFQKVEKIGEG-YGVVYKARNK-LTGEVVALKKIRL-------VPSTAIREISLLKELNHPNIVKLLDVIHTE-----NKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGL---------------VVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSEIDQLFRIFRTLGT----------PD---EVVWPGVTSMPDYKPSFPKWARQDFS-KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL---------------------------------------------------------------------------------
85 PsiBlast_CBE 75.2240%-124 - C1 -2VTP CDK2_HUMAN A:[1-286] MENFQKVEKIGEGTYGVVYKARNK-LTGEVVALKKI---------VPSTAIREISLLKELNHPNIVKLLDVIHTE-----NKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAF----------EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSEIDQLFRIFRTLGT----------PD---EVVWPGVTSMPDYKPSFPKWARQDFS-KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL---------------------------------------------------------------------------------
57 PsiBlast_CBE 75.1240%-124 - C1 -3LFS CDK2_HUMAN A:[1-286] MENFQKVEKIGEGTYGVVYKARNK-LTGEVVALKKIR---------PSTAIREISLLKELNHPNIVKLLDVIHTE-----NKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGV-PVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSEIDQLFRIFRTLGT----------PD---EVVWPGVTSMPDYKPSFPKWARQDFS-KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL---------------------------------------------------------------------------------
71 PsiBlast_CBE 75.0840%-116 - C1 -2XMY CDK2_HUMAN A:[1-286] MENFQKVEKIGEGTYGVVYKARNK-LTGEVVALKKIRLD-T---GVPSTAIREISLLKELNHPNIVKLLDVIHTE-----NKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGV-PVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSEIDQLFRIFRTLGT----------PD---EVVWPGVTSMPDYKPSFPKWARQDFS-KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL---------------------------------------------------------------------------------
50 PsiBlast_CBE 75.0040%-122 - C1 -3TIZ CDK2_HUMAN A:[2-286] -ENFQKVEKIGEGTYGVVYKARNK-LTGEVVALKKIR-----TEGVPSTAIREISLLKELNHPNIVKLLDVIHTE-----NKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGV-PVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSEIDQLFRIFRTLGT----------PD---EVVWPGVTSMPDYKPSFPKWARQDFS-KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL---------------------------------------------------------------------------------
72 PsiBlast_CBE 74.9840%-113 - C1 -2X1N CDK2_HUMAN C:[1-286] MENFQKVEKIGEGTYGVVYKARNK-LTGEVVALKKIRLD-TETEGVPSTAIREISLLKELNHPNIVKLLDVIHTE-----NKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGV-PVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSEIDQLFRIFRTLGT----------PD---EVVWPGVTSMPDYKPSFPKWARQDFS-KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLR----------------------------------------------------------------------------------
98 PsiBlast_CBE 74.9440%-115 - C1 -2UUE CDK2_HUMAN A:[1-286] MENFQKVEKIGEGTYGVVYKARNK-LTGEVVALKKIRLD-TETEGVPSTAIREISLLKELNHPNIVKLLDVIHTE-----NKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGV-PVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSEIDQLFRIFRTLGT----------PD---EVVWPGVTSMPDYKPSFPKWARQDFS-KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHL-----------------------------------------------------------------------------------
76 PsiBlast_CBE 74.7440%-118 - C1 -2W1H CDK2_HUMAN A:[1-286] MENFQKVEKIGEGTYGVVYKARNK-LTGEVVALKKIR-----TEGVPSTAIREISLLKELNHPNIVKLLDVIHTE-----NKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAF------------VTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSEIDQLFRIFRTLGT----------PD---EVVWPGVTSMPDYKPSFPKWARQDFS-KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL---------------------------------------------------------------------------------
67 PsiBlast_CBE 74.7340%-115 - C1 -3EJ1 CDK2_HUMAN C:[1-286] MENFQKVEKIGEGTYGVVYKARNK-LTGEVVALKKIRL----TEGVPSTAIREISLLKELNHPNIVKLLDVIHTE-----NKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGV-PVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSEIDQLFRIFRTLGT----------PD---EVVWPGVTSMPDYKPSFPKWARQDFS-KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLR----------------------------------------------------------------------------------
74 PsiBlast_CBE 74.7040%-112 - C1 -2WEV CDK2_HUMAN C:[1-286] MENFQKVEKIGEGTYGVVYKARNK-LTGEVVALKKIRLD-TETEGVPSTAIREISLLKELNHPNIVKLLDVIHTE-----NKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGV-PVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSEIDQLFRIFRTLGT----------PD---EVVWPGVTSMPDYKPSFPKWARQDFS-KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLR----------------------------------------------------------------------------------
91 PsiBlast_CBE 74.6540%-121 - C1 -2VTI CDK2_HUMAN A:[1-286] MENFQKVEKIGEGTYGVVYKARNK-LTGEVVALKKI---------VPSTAIREISLLKELNHPNIVKLLDVIHTE-----NKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAF-----------VVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSEIDQLFRIFRTLGT----------PD---EVVWPGVTSMPDYKPSFPKWARQDFS-KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL---------------------------------------------------------------------------------
75 PsiBlast_CBE 74.6240%-115 - C1 -2WEV CDK2_HUMAN A:[1-286] MENFQKVEKIGEGTYGVVYKARNK-LTGEVVALKKIRLD-TETEGVPSTAIREISLLKELNHPNIVKLLDVIHTE-----NKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGV-PVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSEIDQLFRIFRTLGT----------PD---EVVWPGVTSMPDYKPSFPKWARQDFS-KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHL-----------------------------------------------------------------------------------
68 PsiBlast_CBE 74.5640%-116 - C1 -3EJ1 CDK2_HUMAN A:[1-286] MENFQKVEKIGEGTYGVVYKARNK-LTGEVVALKKIRL----TEGVPSTAIREISLLKELNHPNIVKLLDVIHTE-----NKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGV-PVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSEIDQLFRIFRTLGT----------PD---EVVWPGVTSMPDYKPSFPKWARQDFS-KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL---------------------------------------------------------------------------------
69 PsiBlast_CBE 74.5340%-119 - C1 -3EID CDK2_HUMAN A:[1-286] MENFQKVEKIGEGTYGVVYKARNK-LTGEVVALKKIRL----TEGVPSTAIREISLLKELNHPNIVKLLDVIHTE-----NKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGV-PVRTYT--VVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSEIDQLFRIFRTLGT----------PD---EVVWPGVTSMPDYKPSFPKWARQDFS-KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLR----------------------------------------------------------------------------------
66 PsiBlast_CBE 74.5240%-114 - C1 -3EOC CDK2_HUMAN A:[1-286] MENFQKVEKIGEGTYGVVYKARNK-LTGEVVALKKIRL----TEGVPSTAIREISLLKELNHPNIVKLLDVIHTE-----NKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGV-PVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSEIDQLFRIFRTLGT----------PD---EVVWPGVTSMPDYKPSFPKWARQDFS-KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL---------------------------------------------------------------------------------
51 PsiBlast_CBE 74.3140%-122 - C1 -3TIY CDK2_HUMAN A:[2-286] -ENFQKVEKIGEGTYGVVYKARNK-LTGEVVALKKIR-----TEGVPSTAIREISLLKELNHPNIVKLLDVIHTE-----NKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGV-PVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSEIDQLFRIFRTLGT----------PD---EVVWPGVTSMPDYKPSFPKWARQDFS-KVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL---------------------------------------------------------------------------------