@TOME V2.3
(Nov 2016)

Ref. - - Doc.
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Alignment:

3D Common Core:

Structural Clustering:

Modeller Result :

Complexes Modeling
Templates Information:
Sequence & Result Tab:

Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : CDKL5_HUMAN: (2015-10-05 )
MKIPNIGNVMNKFEILGVVGEGAYGVVLKCRHKETHEIVAIKKFKDSEENEEVKETTLRELKMLRTLKQENIVELKEAFRRRGKLYLVFEYVEKNMLELLEEMPNGVPPEKVKSYIYQLIKAIHWCHKNDIVHRDIKPENLLISHNDVLKLCDFGFARNLSEGNNANYTEYVATRWYRSPELLLGAPYGKSVDMWSVGCILGELSDGQPLFPGESEIDQLFTIQKVLGPLPSEQMKLFYSNPRFHGLRFPAVNHPQSLERRYLGILNSVLLDLMKNLLKLDPADRYLTEQCLNHPTFQTQRLLDRSPSRSAKRKPYHVESSTLSNRNQAGKSTALQSHHRSNSKDIQNLSVGLPRADEGLPANESFLNGNLAGASLSPLHTKTYQASSQPGSTSKDLTNNNIPHLLSPKEAKSKTEFDFNIDPKPSEGPGTKYLKSNSRSQQNRHSFMESSQSKAGTLQPNEKQSRHSYIDTIPQSSRSPSYRTKAKSHGALSDSKSVSNLSEARAQIAEPSTSRYFPSSCLDLNSPTSPTPTRHSDTRTLLSPSGRNNRNEGTLDSRRTTTRHSKTMEELKLPEHMDSSHSHSLSAPHESFSYGLGYTSPFSSQQRPHRHSMYVTRDKVRAKGLDGSLSIGQGMAARANSLQLLSPQPGEQLPPEMTVARSSVKETSREGTSSFHTRQKSEGGVYHDPHSDDGTAPKENRHLYNDPVPRRVGSFYRVPSPRPDNSFHENNVSTRVSSLPSESSSGTNHSKRQPAFDPWKSPENISHSEQLKEKEKQGFFRSMKKKKKKSQTVPNSDSPDLLTLQKSIHSASTPSSRPKEWRPEKISDLQTQSQPLKSLRKLLHLSSASNHPASSDPRFQPLTAQQTKNSFSEIRIHPLSQASGGSSNIRQEPAPKGRPALQLPDGGCDGRRQRHHSGPQDRRFMLRTTEQQGEYFCCGDPKKPHTPCVPNRALHRPISSPAPYPVLQVRGTSMCPTLQVRGTDAFSCPTQQSGFSFFVRHVMREALIHRAQVNQAALLTYHENAALTGK

Atome Classification :

(95 SA) .........10........20........30........40........50........60........70........80........90........100..-..--...110.......120.......130.......140.......150.......160.......170.......180..-.-..-..190.......200....-...210.......220.......230.......--------240.....-..250.......260.......270.......280.......290.......300...-....310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570.......580.......590.......600.......610.......620.......630.......640.......650.......660.......670.......680.......690.......700.......710.......720.......730.......740.......750.......760.......770.......780.......790.......800.......810.......820.......830.......840.......850.......860.......870.......880.......890.......900.......910.......920.......930.......940.......950.......960.......970.......980.......990.......1000......1010......1020......1030
(Atome) (Ident) (Tito) (Num) (Ligand) (Uniprot) MKIPNIGNVMNKFEILGVVGEGAYGVVLKCRHKETHEIVAIKKFKDSEENEEVKETTLRELKMLRTLKQENIVELKEAFRRRGKLYLVFEYVEKNMLELLEEMP-NG--VPPEKVKSYIYQLIKAIHWCHKNDIVHRDIKPENLLISHNDVLKLCDFGFARNLSEGNNANYTEYVATRWYRSPELLL-G-AP-YGKSVDMWSVGCILGELSD-GQPLFPGESEIDQLFTIQKVLGPLPSEQMKLFY--------SNPRFHGL-RFPAVNHPQSLERRYLGILNSVLLDLMKNLLKLDPADRYLTEQCLNHPTFQTQRLLDR-SPSRSAKRKPYHVESSTLSNRNQAGKSTALQSHHRSNSKDIQNLSVGLPRADEGLPANESFLNGNLAGASLSPLHTKTYQASSQPGSTSKDLTNNNIPHLLSPKEAKSKTEFDFNIDPKPSEGPGTKYLKSNSRSQQNRHSFMESSQSKAGTLQPNEKQSRHSYIDTIPQSSRSPSYRTKAKSHGALSDSKSVSNLSEARAQIAEPSTSRYFPSSCLDLNSPTSPTPTRHSDTRTLLSPSGRNNRNEGTLDSRRTTTRHSKTMEELKLPEHMDSSHSHSLSAPHESFSYGLGYTSPFSSQQRPHRHSMYVTRDKVRAKGLDGSLSIGQGMAARANSLQLLSPQPGEQLPPEMTVARSSVKETSREGTSSFHTRQKSEGGVYHDPHSDDGTAPKENRHLYNDPVPRRVGSFYRVPSPRPDNSFHENNVSTRVSSLPSESSSGTNHSKRQPAFDPWKSPENISHSEQLKEKEKQGFFRSMKKKKKKSQTVPNSDSPDLLTLQKSIHSASTPSSRPKEWRPEKISDLQTQSQPLKSLRKLLHLSSASNHPASSDPRFQPLTAQQTKNSFSEIRIHPLSQASGGSSNIRQEPAPKGRPALQLPDGGCDGRRQRHHSGPQDRRFMLRTTEQQGEYFCCGDPKKPHTPCVPNRALHRPISSPAPYPVLQVRGTSMCPTLQVRGTDAFSCPTQQSGFSFFVRHVMREALIHRAQVNQAALLTYHENAALTGK
1 PsiBlast_PDB 95.8899%-112 - C2 -4BGQ CDKL5_HUMAN A:[10-303] --------VMNKFEILGVVGEGAYGVVLKCRHKETHEIVAIKKFK-------VKETTLRELKMLRTLKQENIVELKEAFRRRGKLYLVFEYVEKNMLELLEEMP-NG--VPPEKVKSYIYQLIKAIHWCHKNDIVHRDIKPENLLISHNDVLKLCDFGFARNLSE-----------TRWYRSPELLL-G-AP-YGKSVDMWSVGCILGELSD-GQPLFPGESEIDQLFTIQKVLGPLPSEQMKLFY--------SNPRFHGL-RFPAVNHPQSLERRYLGILNSVLLDLMKNLLKLDPADRYLTEQCLNHPTFQTQRL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2 PsiBlast_PDB 76.6547%-106 - C2 -4AAA CDKL2_HUMAN A:[24-318] ---------MEKYENLGLVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHENLVNLLEVCKKKKRWYLVFEFVDHTILDDLELFP-NG--LDYQVVQKYLFQIINGIGFCHSHNIIHRDIKPENILVSQSGVVKLCDFGFA-------------EVATRWYRAPELLV-GDVK-YGKAVDVWAIGCLVTEMFM-GEPLFPGDSDIDQLYHIMMCLGNLIPRHQELFN--------KNPVFAGV-RLPEIKEREPLERRYPK-LSEVVIDLAKKCLHIDPDKRPFCAELLHHDFFQMDGFAER-FSQELQL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3 PsiBlast_PDB 73.8047% -96 - C2 -4BBM CDKL2_HUMAN A:[24-318] ---------MEKYENLGLVG--SYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHENLVNLLEVCKKKKRWYLVFEFVDHTILDDLELFP-NG--LDYQVVQKYLFQIINGIGFCHSHNIIHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEV-YDDEVATRWYRAPELLV-GDVK-YGKAVDVWAIGCLVTEMFM-GEPLFPGDSDIDQLYHIMMCLGNLIPRHQELFN--------KNPVFAGV-RLPEIKEREPLERRYPK-LSEVVIDLAKKCLHIDPDKRPFCAELLHHDFFQMDGFAER-FSQELQLKVQKDA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24 PsiBlast_CBE 72.5840% -91 - C2 -4AU8 CDK5_HUMAN B:[7-290] -----------KYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRL----EGVPSSALREICLLKELKHKNIVRLHDVLHS-KKLTLVFEFCDQDLKKYFDSCN-GD--LDPEIVKSFLFQLLKGLGFCHSRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPV-------VVTLWYRPPDVLF-G-AKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSMT--------KLPDYKPYPMYPATTSLVNVVPK----LNATGRDLLQNLLKCNPVQRISAEEALQHPYFSDF-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21 PsiBlast_CBE 72.4447%-103 - C2 -4BBM CDKL2_HUMAN B:[24-318] ---------MEKYENLG-----SYGMVMKCRNKDTGRIVAIKKF---------KKIAMREIKLLKQLRHENLVNLLEVC------YLVFEFVDHTILDDLELFP-NG--LDYQVVQKYLFQIINGIGFCHSHNIIHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEV-YDDEVATRWYRAPELLV-GDVK-YGKAVDVWAIGCLVTEMFM-GEPLFPGDSDIDQLYHIMMCLGNLIPRHQELFN--------KNPVFAGV-RLPEIKEREPLERRYPK-LSEVVIDLAKKCLHIDPDKRPFCAELLHHDFFQMDGFAER-FSQELQLKVQKDA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23 PsiBlast_CBE 72.4246% -93 - C2 -4AGU CDKL1_HUMAN B:[4-293] -----------KYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKFLES--DPVIKKIALREIRMLKQLKHPNLVNLLEVFRRKRRLHLVFEYCDHTVLHELDRYQ-RG--VPEHLVKSITWQTLQAVNFCHKHNCIHRDVKPENILITKHSVIKLCDFGFARLLT-------------RWYRSPELLV-GDTQ-YGPPVDVWAIGCVFAELLS-GVPLWPGKSDVDQLYLIRKTLGDLIPRHQQVFS--------TNQYFSGV-KIPDPEDMEPLELKFPNI-SYPALGLLKGCLHMDPTERLTCEQLLHHPYFENIRE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4 PsiBlast_PDB 72.3646% -91 - C2 -4AGU CDKL1_HUMAN A:[3-292] ----------EKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKFLESED-PVIKKIALREIRMLKQLKHPNLVNLLEVFRRKRRLHLVFEYCDHTVLHELDRYQ-RG--VPEHLVKSITWQTLQAVNFCHKHNCIHRDVKPENILITKHSVIKLCDFGFARLLT-------------RWYRSPELLV-GDTQ-YGPPVDVWAIGCVFAELLS-GVPLWPGKSDVDQLYLIRKTLGDLIPRHQQVFS--------TNQYFSGV-KIPDPEDMEPLELKFPNI-SYPALGLLKGCLHMDPTERLTCEQLLHHPYFENIR----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22 PsiBlast_CBE 72.2746% -91 - C2 -4AGU CDKL1_HUMAN C:[3-292] ----------EKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQLKHPNLVNLLEVFRRKRRLHLVFEYCDHTVLHELDRYQ-RG--VPEHLVKSITWQTLQAVNFCHKHNCIHRDVKPENILITKHSVIKLCDFGFARLLT-------------RWYRSPELLV-GDTQ-YGPPVDVWAIGCVFAELLS-GVPLWPGKSDVDQLYLIRKTLGDLIPRHQQVFS--------TNQYFSGV-KIPDPEDMEPLELKFPNI-SYPALGLLKGCLHMDPTERLTCEQLLHHPYFENIR----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5 PsiBlast_PDB 71.6640% -88 - C2 -3ZDU CDKL3_HUMAN A:[2-303] ---------MEMYETLGKVGEGSYGTVMKCKHKNTGQIVAIKIFY--------NKIAMREIKFLKQFHHENLVNLIEVFRQKKKIHLVFEFIDHTVLDELQHYC-HG--LESKRLRKYLFQILRAIDYLHSNNIIHRDIKPENILVSQSGITKLCDFGFART-----DI-YDDEVATRWYRAPELVLKD-TS-YGKPVDIWALGCMIIEMAT-GNPYLPSSSDLDLLHKIVLKVGNLSPHLQNIFS--------KSPIFAGV-VLPQVQHPKNARKKYPK-LNGLLADIVHACLQIDPADRISSSDLLHHEYFTRDGFIEKFMPELKAKLLQEAKV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6 PsiBlast_PDB 69.4140% -88 - C2 -4AU8 CDK5_HUMAN A:[7-290] -----------KYEKLEKIGEGTYGTVFKAKNRETHEIVALKRV---------PSSALREICLLKELKHKNIVRLHDVLH---KLTLVFEFCDQDLKKYFDSCN-GD--LDPEIVKSFLFQLLKGLGFCHSRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVR---SAEVVTLWYRPPDVLF-G-AKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSMT--------KLPDYKPYPMYPATTSLVNVVPK----LNATGRDLLQNLLKCNPVQRISAEEALQHPYFSDF-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10 PsiBlast_PDB 68.7740% -86 - C2 -1UNL CDK5_HUMAN A:[1-286] ---------MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKNIVRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCN-GD--LDPEIVKSFLFQLLKGLGFCHSRNVLHRDLKPQNLLINRNGELKLANFGLARAFGIPVRC-YSAEVVTLWYRPPDVLF-G-AKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSMT--------KLPDYKPYPMYPATTSLVNVVPK----LNATGRDLLQNLLKCNPVQRISAEEALQHPYFSDFCPP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
77 PsiBlast_CBE 68.0938% -85 - C2 -3QZH CDK2_HUMAN A:[9-295] ---------MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIR----TEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTG--IPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVR-TYTHEVVTLWYRAPEILL-G-CKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSEIDQLFRIFRTLGT-PDEVVWPGVTSMPDYKPSFPKWARQ-DFSKVVPPLDEDGR----------SLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP-HLRL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
37 PsiBlast_CBE 67.5438% -89 - C2 -3RPR CDK2_HUMAN A:[9-295] ---------MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIR--------PSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTG--IPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGV---------VVTLWYRAPEILL-G-CKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSEIDQLFRIFRTLGT-PDEVVWPGVTSMPDYKPSFPKWARQ-DFSKVVPPLDEDGR----------SLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP-HLRL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
72 PsiBlast_CBE 67.4938% -86 - C2 -3R28 CDK2_HUMAN A:[9-295] ---------MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIR----TEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTG--IPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVR-TYTHEVVTLWYRAPEILL-G-CKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSEIDQLFRIFRTLGT-PDEVVWPGVTSMPDYKPSFPKWARQ-DFSKVVPPLDEDGR----------SLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP-HLRL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
101 PsiBlast_CBE 67.2738% -86 - C2 -3QQF CDK2_HUMAN A:[9-295] ---------MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIR----TEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTG--IPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVR-TYTHEVVTLWYRAPEILL-G-CKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSEIDQLFRIFRTLGT-PDEVVWPGVTSMPDYKPSFPKWARQ-DFSKVVPPLDEDGR----------SLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP-HLRL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36 PsiBlast_CBE 67.2338% -82 - C2 -3RPV CDK2_HUMAN A:[9-295] ---------MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIR----TEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTG--IPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVR-TYTHEVVTLWYRAPEILL-G-CKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSEIDQLFRIFRTLGT-PDEVVWPGVTSMPDYKPSFPKWARQ-DFSKVVPPLDEDGR----------SLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP-HLRL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
63 PsiBlast_CBE 67.0638% -86 - C2 -3R83 CDK2_HUMAN A:[9-295] ---------MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIR----TEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTG--IPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVR-TYTHEVVTLWYRAPEILL-G-CKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSEIDQLFRIFRTLGT-PDEVVWPGVTSMPDYKPSFPKWARQ-DFSKVVPPLDEDGR----------SLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP-HLRL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
42 PsiBlast_CBE 67.0438% -85 - C2 -3RM7 CDK2_HUMAN A:[9-295] ---------MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIR----TEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTG--IPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVR-TYTHEVVTLWYRAPEILL-G-CKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSEIDQLFRIFRTLGT-PDEVVWPGVTSMPDYKPSFPKWARQ-DFSKVVPPLDEDGR----------SLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP-HLRL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
52 PsiBlast_CBE 66.8638% -90 - C2 -3RAH CDK2_HUMAN A:[9-295] ---------MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIR--------PSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTG--IPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGV---------VVTLWYRAPEILL-G-CKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSEIDQLFRIFRTLGT-PDEVVWPGVTSMPDYKPSFPKWARQ-DFSKVVPPLDEDGR----------SLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP-HLRL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
66 PsiBlast_CBE 66.7538% -89 - C2 -3R7U CDK2_HUMAN A:[9-295] ---------MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIR--------PSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTG--IPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGV---------VVTLWYRAPEILL-G-CKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSEIDQLFRIFRTLGT-PDEVVWPGVTSMPDYKPSFPKWARQ-DFSKVVPPLDEDGR----------SLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP-HLRL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
93 PsiBlast_CBE 66.6138% -84 - C2 -3QTQ CDK2_HUMAN A:[9-295] ---------MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIR----TEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTG--IPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVR-TYTHEVVTLWYRAPEILL-G-CKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSEIDQLFRIFRTLGT-PDEVVWPGVTSMPDYKPSFPKWARQ-DFSKVVPPLDEDGR----------SLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP-HLRL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
91 PsiBlast_CBE 66.6138% -89 - C2 -3QTS CDK2_HUMAN A:[9-295] ---------MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIR--------PSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTG--IPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGV---------VVTLWYRAPEILL-G-CKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSEIDQLFRIFRTLGT-PDEVVWPGVTSMPDYKPSFPKWARQ-DFSKVVPPLDEDGR----------SLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP-HLRL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29 PsiBlast_CBE 66.4338% -87 - C2 -4EZ3 CDK2_HUMAN A:[9-295] ---------MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIR----TEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTG--IPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVR-TYTHEVVTLWYRAPEILL-G-CKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSEIDQLFRIFRTLGT-PDEVVWPGVTSMPDYKPSFPKWARQ-DFSKVVPPLDEDGR----------SLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP-HLRL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33 PsiBlast_CBE 66.3338% -89 - C2 -3S00 CDK2_HUMAN A:[9-295] ---------MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIR----TEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTG--IPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVR-TYTHEVVTLWYRAPEILL-G-CKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSEIDQLFRIFRTLGT-PDEVVWPGVTSMPDYKPSFPKWARQ-DFSKVVPPLDEDGR----------SLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP-HLRL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
69 PsiBlast_CBE 66.2938% -85 - C2 -3R73 CDK2_HUMAN A:[9-295] ---------MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIR----TEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTG--IPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVR-TYTHEVVTLWYRAPEILL-G-CKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSEIDQLFRIFRTLGT-PDEVVWPGVTSMPDYKPSFPKWARQ-DFSKVVPPLDEDGR----------SLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP-HLRL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
68 PsiBlast_CBE 66.1538% -86 - C2 -3R7E CDK2_HUMAN A:[9-295] ---------MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIR----TEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTG--IPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVR-TYTHEVVTLWYRAPEILL-G-CKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSEIDQLFRIFRTLGT-PDEVVWPGVTSMPDYKPSFPKWARQ-DFSKVVPPLDEDGR----------SLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP-HLRL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
81 PsiBlast_CBE 66.1438% -84 - C2 -3QXO CDK2_HUMAN A:[9-295] ---------MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIR----TEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTG--IPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVR-TYTHEVVTLWYRAPEILL-G-CKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSEIDQLFRIFRTLGT-PDEVVWPGVTSMPDYKPSFPKWARQ-DFSKVVPPLDEDGR----------SLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP-HLRL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
54 PsiBlast_CBE 66.1338% -88 - C2 -3R9N CDK2_HUMAN A:[9-295] ---------MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIR--------PSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTG--IPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGV---------VVTLWYRAPEILL-G-CKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSEIDQLFRIFRTLGT-PDEVVWPGVTSMPDYKPSFPKWARQ-DFSKVVPPLDEDGR----------SLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP-HLRL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
38 PsiBlast_CBE 66.1338% -84 - C2 -3RPO CDK2_HUMAN A:[9-295] ---------MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIR----TEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTG--IPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVR-TYTHEVVTLWYRAPEILL-G-CKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSEIDQLFRIFRTLGT-PDEVVWPGVTSMPDYKPSFPKWARQ-DFSKVVPPLDEDGR----------SLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP-HLRL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19 PsiBlast_PDB 66.1338% -82 - C2 -3PXY CDK2_HUMAN A:[9-295] ---------MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIR----TEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTG--IPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVR-TYTHEVVTLWYRAPEILL-G-CKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSEIDQLFRIFRTLGT-PDEVVWPGVTSMPDYKPSFPKWARQ-DFSKVVPPLDEDGR----------SLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP-HLRL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8 PsiBlast_PDB 66.0240% -88 - C2 -1UNG CDK5_HUMAN A:[1-286] ---------MQKYEKLEKI----YGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKNIVRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCN-GD--LDPEIVKSFLFQLLKGLGFCHSRNVLHRDLKPQNLLINRNGELKLANFGLARAFGIPVRC-YSAEVVTLWYRPPDVLF-G-AKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSMT--------KLPDYKPYPMYPATTSLVNVVPK----LNATGRDLLQNLLKCNPVQRISAEEALQHPYFSDFCPP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
100 PsiBlast_CBE 65.9838% -82 - C2 -3QQG CDK2_HUMAN A:[9-295] ---------MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIR----TEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTG--IPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVR-TYTHEVVTLWYRAPEILL-G-CKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSEIDQLFRIFRTLGT-PDEVVWPGVTSMPDYKPSFPKWARQ-DFSKVVPPLDEDGR----------SLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP-HLRL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
51 PsiBlast_CBE 65.8838% -85 - C2 -3RAI CDK2_HUMAN A:[9-295] ---------MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIR----TEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTG--IPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVR-TYTHEVVTLWYRAPEILL-G-CKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSEIDQLFRIFRTLGT-PDEVVWPGVTSMPDYKPSFPKWARQ-DFSKVVPPLDEDGR----------SLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP-HLRL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
97 PsiBlast_CBE 65.8438% -83 - C2 -3QQK CDK2_HUMAN A:[9-295] ---------MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIR----TEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTG--IPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVR-TYTHEVVTLWYRAPEILL-G-CKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSEIDQLFRIFRTLGT-PDEVVWPGVTSMPDYKPSFPKWARQ-DFSKVVPPLDEDGR----------SLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP-HLRL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
40 PsiBlast_CBE 65.8438% -84 - C2 -3RNI CDK2_HUMAN A:[9-295] ---------MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIR----TEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTG--IPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVR-TYTHEVVTLWYRAPEILL-G-CKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSEIDQLFRIFRTLGT-PDEVVWPGVTSMPDYKPSFPKWARQ-DFSKVVPPLDEDGR----------SLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP-HLRL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
95 PsiBlast_CBE 65.8138% -86 - C2 -3QRT CDK2_HUMAN A:[9-295] ---------MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIR----TEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTG--IPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVR-TYTHEVVTLWYRAPEILL-G-CKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSEIDQLFRIFRTLGT-PDEVVWPGVTSMPDYKPSFPKWARQ-DFSKVVPPLDEDGR----------SLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP-HLRL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------