@TOME V2.3
(Nov 2016)

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Alignment:

3D Common Core:

Structural Clustering:

Modeller Result :

Complexes Modeling
Templates Information:
Sequence & Result Tab:

Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : CHK2_HUMAN: (2015-10-05 )
MSRESDVEAQQSHGSSACSQPHGSVTQSQGSSSQSQGISSSSTSTMPNSSQSSHSSSGTLSSLETVSTQELYSIPEDQEPEDQEPEEPTPAPWARLWALQDGFANLECVNDNYWFGRDKSCEYCFDEPLLKRTDKYRTYSKKHFRIFREVGPKNSYIAYIEDHSGNGTFVNTELVGKGKRRPLNNNSEIALSLSRNKVFVFFDLTVDDQSVYPKALRDEYIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREADPALNVETEIEILKKLNHPCIIKIKNFFDAEDYYIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETSLMRTLCGTPTYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQDEDMKRKFQDLLSEENESTALPQVLAQPSTSRKRPREGEAEGAETTKRPAVCAAVL

Atome Classification :

(71 SA) .........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.........260.......270------.---.......280........290-..-.-.-.-.-.300.......310...--------------------------------------...----.320.......330.......340.......350......-.-360-.......370-...-----....380-.......390....---...400-.......410.......420.......--430.......440.......450.......460.......470.......480......--------.490.......500.......510.......520.......530.......540.
(Atome) (Ident) (Tito) (Num) (Ligand) (Uniprot) MSRESDVEAQQSHGSSACSQPHGSVTQSQGSSSQSQGISSSSTSTMPNSSQSSHSSSGTLSSLETVSTQELYSIPEDQEPEDQEPEEPTPAPWARLWALQDGFANLECVNDNYWFGRDKSCEYCFDEPLLKRTDKYRTYSKKHFRIFREVGPKNSYIAYIEDHSGNGTFVNTELVGKGKRRPLNNNSEIALSLSRNKVFVFFDLTVDDQSVYPKALRDEYIMSKTLGSGACGEVKLAFERKTCKKVAIKI--ISKRKFAIGSAREADPALNVE-------T---EIEILKKLN-HPCIIKIKNFF-DA-E-D-Y-Y-IVLELMEGGELFDKVVG--------------------------------------NKR----LKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQ-E-EDC-LIKITDFGHS-KIL-----GETSLMR-TLCGTPTYLAPEVL---VSVGTA-GYNRAVDCWSLGVILFICLSGYPPFSE--HRTQVSLKDQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQD--------EDMKRKFQDLLSEENESTALPQVLAQPSTSRKRPREGEAEGAETTKRPAVCAAVL
25 PsiBlast_CBE 74.94100%-133 - C1 -4BDG CHK2_HUMAN A:[8-310] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SVYPKALRDEYIMSKTLGS---GEVKLAFERKTCKKVAIKI--ISK---------------NVE-------T---EIEILKKLN-HPCIIKIKNFF-DA-E-D-Y-Y-IVLELMEGGELFDKVVG--------------------------------------NKR----LKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQ-E-EDC-LIKITDFGHS-KIL-----GETSLMR-TLCGTPTYLAPEVL---VSVGTA-GYNRAVDCWSLGVILFICLSGYPPFSE--HRTQVSLKDQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQD--------EDMKRKFQDLLSEENESTALPQVL-------------------------------
23 PsiBlast_CBE 74.86100%-129 - C1 -4BDI CHK2_HUMAN A:[8-313] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SVYPKALRDEYIMSKTLG----GEVKLAFERKTCKKVAIKI--ISK-------------ALNVE-------T---EIEILKKLN-HPCIIKIKNFF-DA-E-D-Y-Y-IVLELMEGGELFDKVVG--------------------------------------NKR----LKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQ-E-EDC-LIKITDFGHS-KIL-----GETSLMR-TLCGTPTYLAPEVL---VSVGTA-GYNRAVDCWSLGVILFICLSGYPPFSE--HRTQVSLKDQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQD--------EDMKRKFQDLLSEENESTALPQVLAQP----------------------------
7 PsiBlast_PDB 74.29100%-132 - C1 -2YCQ CHK2_HUMAN A:[3-302] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VYPKALRDEYIMSKTLGSGACGEVKLAFERKTCKKVAIKI--ISK---------------NVE-------T---EIEILKKLN-HPCIIKIKNFF-DA-E-D-Y-Y-IVLELMEGGELFDKVVG--------------------------------------NKR----LKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQ-E-EDC-LIKITDFGHS-KIL-----GETSLMR-TLCGTPTYLAPEVL---VSVGTA-GYNRAVDCWSLGVILFICLSGYPPFSE--HRTQVSLKDQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQD--------EDMKRKFQDLLSEENESTALPQ---------------------------------
6 PsiBlast_PDB 73.84100%-133 - C1 -2YIT CHK2_HUMAN A:[3-302] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VYPKALRDEYIMSKTLGSGACGEVKLAFERKTCKKVAIKI--ISK--------------LNVE-------T---EIEILKKLN-HPCIIKIKNFF-DA-E-D-Y-Y-IVLELMEGGELFDKVVG--------------------------------------NKR----LKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQ-E-EDC-LIKITDFGHS-KIL-----GETSLMR-TLCGTPTYLAPEVL---VSVGTA-GYNRAVDCWSLGVILFICLSGYPPFSE--HRTQVSLKDQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQD--------EDMKRKFQDLLSEENESTALPQ---------------------------------
13 PsiBlast_PDB 73.51100%-129 - C1 -2WTI CHK2_HUMAN A:[8-310] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SVYPKALRDEYIMSKTLGS----EVKLAFERKTCKKVAIKI--ISK------------PALNVE-------T---EIEILKKLN-HPCIIKIKNFF-DA-E-D-Y-Y-IVLELMEGGELFDKVVG--------------------------------------NKR----LKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQ-E-EDC-LIKITDFGHS-KIL------ETSLMR-TLCGTPTYLAPEVL---VSVGTA-GYNRAVDCWSLGVILFICLSGYPPFSE--HRTQVSLKDQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQD--------EDMKRKFQDLLSEENESTALPQVL-------------------------------
31 PsiBlast_CBE 73.20100%-130 - C1 -2YCF CHK2_HUMAN A:[2-302] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SVYPKALRDEYIMSKTLGSGACGEVKLAFERKTCKKVAIKI--ISK---------------NVE-------T---EIEILKKLN-HPCIIKIKNFF-DA-E-D-Y-Y-IVLELMEGGELFDKVVG--------------------------------------NKR----LKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQ-E-EDC-LIKITDFGHS-KIL-----GETSLMR-TLCGTPTYLAPEVL---VSVGTA-GYNRAVDCWSLGVILFICLSGYPPFSE--HRTQVSLKDQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQD--------EDMKRKFQDLLSEENESTALPQ---------------------------------
128 HHSearch 73.19100%-130 - C1 -2YCF CHK2_HUMAN A:[2-302] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SVYPKALRDEYIMSKTLGSGACGEVKLAFERKTCKKVAIKI--ISK---------------NVE-------T---EIEILKKLN-HPCIIKIKNFF-DA-E-D-Y-Y-IVLELMEGGELFDKVVG--------------------------------------NKR----LKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQ-E-EDC-LIKITDFGHS-KIL-----GETSLMR-TLCGTPTYLAPEVL---VSVGTA-GYNRAVDCWSLGVILFICLSGYPPFSE--HRTQVSLKDQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQD--------EDMKRKFQDLLSEENESTALPQ---------------------------------
26 PsiBlast_CBE 73.09100%-133 - C1 -4BDF CHK2_HUMAN A:[8-310] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SVYPKALRDEYIMSKTLG----GEVKLAFERKTCKKVAIKI--ISK---------------NVE-------T---EIEILKKLN-HPCIIKIKNFF-DA-E-D-Y-Y-IVLELMEGGELFDKVVG--------------------------------------NKR----LKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQ-E-EDC-LIKITDFGHS-KIL-----GETSLMR-TLCGTPTYLAPEVL---VSVGTA-GYNRAVDCWSLGVILFICLSGYPPFSE--HRTQVSLKDQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQD--------EDMKRKFQDLLSEENESTALPQVL-------------------------------
21 PsiBlast_CBE 73.02100%-130 - C1 -4BDK CHK2_HUMAN A:[9-311] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VYPKALRDEYIMSKTLG----GEVKLAFERKTCKKVAIKI--ISK-------------ALNVE-------T---EIEILKKLN-HPCIIKIKNFF-DA-E-D-Y-Y-IVLELMEGGELFDKVVG--------------------------------------NKR----LKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQ-E-EDC-LIKITDFGHS-KIL-----GETSLMR-TLCGTPTYLAPEVL---VSVGTA-GYNRAVDCWSLGVILFICLSGYPPFSE--HRTQVSLKDQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQD--------EDMKRKFQDLLSEENESTALPQVLA------------------------------
29 PsiBlast_CBE 72.87100%-133 - C1 -4BDC CHK2_HUMAN A:[8-310] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SVYPKALRDEYIMSKTLGS----EVKLAFERKTCKKVAIKI--ISK---------------NVE-------T---EIEILKKLN-HPCIIKIKNFF-DA-E-D-Y-Y-IVLELMEGGELFDKVVG--------------------------------------NKR----LKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQ-E-EDC-LIKITDFGHS-KIL------ETSLMR-TLCGTPTYLAPEVL---VSVGTA-GYNRAVDCWSLGVILFICLSGYPPFSE--HRTQVSLKDQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQD--------EDMKRKFQDLLSEENESTALPQVL-------------------------------
22 PsiBlast_CBE 72.86100%-132 - C1 -4BDJ CHK2_HUMAN A:[9-311] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VYPKALRDEYIMSKTLG-----EVKLAFERKTCKKVAIKI--ISK---------------NVE-------T---EIEILKKLN-HPCIIKIKNFF-DA-E-D-Y-Y-IVLELMEGGELFDKVVG--------------------------------------NKR----LKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQ-E-EDC-LIKITDFGHS-KIL------ETSLMR-TLCGTPTYLAPEVL---VSVGTA-GYNRAVDCWSLGVILFICLSGYPPFSE--HRTQVSLKDQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQD--------EDMKRKFQDLLSEENESTALPQVLA------------------------------
4 PsiBlast_PDB 72.86100%-132 - C1 -2YIQ CHK2_HUMAN A:[3-302] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VYPKALRDEYIMSKTLG----GEVKLAFERKTCKKVAIKI--ISK----------------VE-------T---EIEILKKLN-HPCIIKIKNFF-DA-E-D-Y-Y-IVLELMEGGELFDKVVG--------------------------------------NKR----LKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQ-E-EDC-LIKITDFGHS-KIL-----GETSLMR-TLCGTPTYLAPEVL---VSVGTA-GYNRAVDCWSLGVILFICLSGYPPFSE--HRTQVSLKDQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQD--------EDMKRKFQDLLSEENESTALPQ---------------------------------
5 PsiBlast_PDB 72.80100%-132 - C1 -2YIR CHK2_HUMAN A:[2-301] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SVYPKALRDEYIMSKTLGSGACGEVKLAFERKTCKKVAIKI--ISK--------------LNVE-------T---EIEILKKLN-HPCIIKIKNFF-DA-E-D-Y-Y-IVLELMEGGELFDKVVG--------------------------------------NKR----LKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQ-E-EDC-LIKITDFGHS-KIL-----GETSLMR-TLCGTPTYLAPEVL---VSVGTA-GYNRAVDCWSLGVILFICLSGYPPFSE--HRTQVSLKDQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQD--------EDMKRKFQDLLSEENESTALP----------------------------------
12 PsiBlast_PDB 72.58100%-132 - C1 -2WTD CHK2_HUMAN A:[8-310] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SVYPKALRDEYIMSKTLGS----EVKLAFERKTCKKVAIKI--ISK------------PALNVE-------T---EIEILKKLN-HPCIIKIKNFF-DA-E-D-Y-Y-IVLELMEGGELFDKVVG--------------------------------------NKR----LKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQ-E-EDC-LIKITDFGHS-KIL-------TSLMR-TLCGTPTYLAPEVL---VSVGTA-GYNRAVDCWSLGVILFICLSGYPPFSE--HRTQVSLKDQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQD--------EDMKRKFQDLLSEENESTALPQVL-------------------------------
14 PsiBlast_PDB 72.35100%-132 - C1 -2WTJ CHK2_HUMAN A:[8-310] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SVYPKALRDEYIMSKTLGS----EVKLAFERKTCKKVAIKI--ISK------------PALNVE-------T---EIEILKKLN-HPCIIKIKNFF-DA-E-D-Y-Y-IVLELMEGGELFDKVVG--------------------------------------NKR----LKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQ-E-EDC-LIKITDFGHS-KIL------ETSLMR-TLCGTPTYLAPEVL---VSVGTA-GYNRAVDCWSLGVILFICLSGYPPFSE--HRTQVSLKDQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQD--------EDMKRKFQDLLSEENESTALPQVL-------------------------------
9 PsiBlast_PDB 72.10100%-131 - C1 -2CN5 CHK2_HUMAN A:[8-302] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SVYPKALRDEYIMSKTLGSGACGEVKLAFERKTCKKVAIKI--ISKR--------------NVE-------T---EIEILKKLN-HPCIIKIKNFF-DA-E-D-Y-Y-IVLELMEGGELFDKVVG--------------------------------------NKR----LKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQ-E-EDC-LIKITDFGHS-KIL-----GETSLMR-TLCGTPTYLAPEVL---VSVGTA-GYNRAVDCWSLGVILFICLSGYPPFSE--HRTQVSLKDQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQD--------EDMKRKFQDLLSEENE---------------------------------------
20 PsiBlast_PDB 71.99100%-135 - C1 -4BDA CHK2_HUMAN A:[8-310] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SVYPKALRDEYIMSKTLGS----EVKLAFERKTCKKVAIKI--ISK---------------NVE-------T---EIEILKKLN-HPCIIKIKNFF-DA-E-D-Y-Y-IVLELMEGGELFDKVVG--------------------------------------NKR----LKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQ-E-EDC-LIKITDFGHS-KIL------ETSLMR-TLCGTPTYLAPEVL---VSVGTA-GYNRAVDCWSLGVILFICLSGYPPFSE--HRTQVSLKDQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQD--------EDMKRKFQDLLSEENESTALPQVL-------------------------------
32 PsiBlast_CBE 71.5699%-132 - C1 -2YCR CHK2_HUMAN A:[3-302] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VYPKALRDEYIMSKTLGS---GEVKLAFERKTCKKVAIKI--ISK---------------NVE-------T---EIEILKKLN-HPCIIKIKNFF-DA-E-D-Y-Y-IVLELMEGGELFDKVVG--------------------------------------NKR----LKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQ-E-EDC-LIKITDFGHS-KIL-----GETSLMR-TLCGTPTYLAPEVL---VSVGTA-GYNRAVDCWSLGVILFICLSGYPPFSE--HRTQVSLKDQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQD--------EDMKRKFQDLLSEENESTAKPQ---------------------------------
28 PsiBlast_CBE 71.38100%-140 - C1 -4BDD CHK2_HUMAN A:[8-310] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SVYPKALRDEYIMSKTL------EVKLAFERKTCKKVAIKI--ISK---------------NVE-------T---EIEILKKLN-HPCIIKIKNFF-DA-E-D-Y-Y-IVLELMEGGELFDKVVG--------------------------------------NKR----LKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQ-E-EDC-LIKITDFGHS-KIL-------TSLMR-TLCGTPTYLAPEVL---VSVGTA-GYNRAVDCWSLGVILFICLSGYPPFSE--HRTQVSLKDQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQD--------EDMKRKFQDLLSEENESTALPQVL-------------------------------
15 PsiBlast_PDB 71.22100%-130 - C1 -2XM9 CHK2_HUMAN A:[9-310] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VYPKALRDEYIMSKTLGS---GEVKLAFERKTCKKVAIKI--ISK------------PALNVE-------T---EIEILKKLN-HPCIIKIKNFF-DA-E-D-Y-Y-IVLELMEGGELFDKVVG--------------------------------------NKR----LKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQ-E-EDC-LIKITDFGHS-KIL-----GETSLMR-TLCGTPTYLAPEVL---VSVGTA-GYNRAVDCWSLGVILFICLSGYPPFSE--HRTQVSLKDQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQD--------EDMKRKFQDLLSEENESTALPQVL-------------------------------
3 PsiBlast_PDB 71.05100%-133 - C1 -2W0J CHK2_HUMAN A:[2-302] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SVYPKALRDEYIMSKTLGS---GEVKLAFERKTCKKVAIKI--ISK---------------NVE-------T---EIEILKKLN-HPCIIKIKNFF-DA-E-D-Y-Y-IVLELMEGGELFDKVVG--------------------------------------NKR----LKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQ-E-EDC-LIKITDFGHS-KIL-------TSLMR-TLCGTPTYLAPEVL---VSVGTA-GYNRAVDCWSLGVILFICLSGYPPFSE--HRTQVSLKDQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQD--------EDMKRKFQDLLSEENE-TALPQ---------------------------------
11 PsiBlast_PDB 70.86100%-129 - C1 -2WTC CHK2_HUMAN A:[9-310] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VYPKALRDEYIMSKTLGS----EVKLAFERKTCKKVAIKI--ISK------------PALNVE-------T---EIEILKKLN-HPCIIKIKNFF-DA-E-D-Y-Y-IVLELMEGGELFDKVVG--------------------------------------NKR----LKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQ-E-EDC-LIKITDFGHS-KIL-------TSLMR-TLCGTPTYLAPEVL---VSVGTA-GYNRAVDCWSLGVILFICLSGYPPFSE--HRTQVSLKDQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQD--------EDMKRKFQDLLSEENESTALPQVL-------------------------------
8 PsiBlast_PDB 69.54100%-130 - C1 -2YCS CHK2_HUMAN A:[2-302] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SVYPKALRDEYIMSKTLGS---GEVKLAFERKTCKKVAIKI--ISK---------------NVE-------T---EIEILKKLN-HPCIIKIKNFF-DA-E-D-Y-Y-IVLELMEGGELFDKVVG--------------------------------------NKR----LKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQ-E-EDC-LIKITDFGHS-KIL-------TSLMR-TLCGTPTYLAPEVL---VSVGTA-GYNRAVDCWSLGVILFICLSGYPPFSE--HRTQVSLKDQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQD--------EDMKRKFQDLLSEENESTALPQ---------------------------------
10 PsiBlast_PDB 67.60100%-135 - C1 -2CN8 CHK2_HUMAN A:[10-301] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YPKALRDEYIMSKTLGS----EVKLAFERKTCKKVAIKI--ISK---------------NVE-------T---EIEILKKLN-HPCIIKIKNFF-DA-E-D-Y-Y-IVLELMEGGELFDKVVG--------------------------------------NKR----LKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQ-E-EDC-LIKITDFGHS-KIL-------TSLMR-TLC--PTYLAPEVL---VSVGTA-GYNRAVDCWSLGVILFICLSGYPPFSE--H---VSLKDQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQD--------EDMKRKFQDLLSEEN----------------------------------------
41 PsiBlast_CBE 54.1942%-126 - C1 -4FG7 KCC1A_HUMAN A:[16-276] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IRDIYDFRDVLGTGAFSEVILAEDKRTQKLVAIKC--IA----------------SME-------N---EIAVLHKIK-HPNIVALDDIY-ES-G-G-HLY-LIMQLVSGGELFDRIVE--------------------------------------KGF----YTERDASRLIFQVLDAVKYLHDLGIVHRDLKPENLLYYSL-D-EDS-KIMISDFGLS-KME-----DPG---------TPGYVAPEVL------AQK---SKAVDCWSIGVIAYILLCGYPPFYD---ENDAKLFEQILKAEYEFDSPYWDDISDSAKDFIRHLMEKDPEKRFTCEQALQHPWIA----------------------------------------------------------------
46 PsiBlast_CBE 53.8942%-128 - C1 -3LIJ ? A:[35-297] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSEMYQRVKKLGS---GEVLLCRDKVTHVERAIKI--I--RK-----SSNS----KLL-------E---EVAVLKLLD-HPNIMKLYDFFEDK-R-N-Y-Y-LVMECYKGGELFDEIIH--------------------------------------RMK----FNEVDAAVIIKQVLSGVTYLHKHNIVHRDLKPENLLLESK-E-KDA-LIKIVDFGLS-AVF-----ENQKKMK-ERLGTAYYIAPEVL-------RK-KYDEKCDVWSIGVILFILLAGYPPFGG--QTDQEILR-KVEKGKYTFDSPEWKNVSEGAKDLIKQMLQFDSQRRISAQQALEHPWIKE--------MCSKKESLPSLANAIENMRKFQNSQKLAQAALLYMASKLTSQEETKELTDIFRHI
93 PsiBlast_CBE 51.1738%-121 - C1 -3MFS CSKP_HUMAN A:[22-294] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FEDVYELCEVIGKGAFSVVRRCINRETGQQFAVKI--VDVAKFT------SSPGLSTE-------DLKREASICHMLK-HPHIVELLETY-SS-D-G-MLY-MVFEFMDGADLCFEIVK--------------------------------------RADAGFVYSEAVASHYMRQILEALRYCHDNNIIHRDVKPENVLLASK-E-NSA-PVKLGDFGVA-IQL-----GESGLVAGGRVGTPHFMAPEV------VKRE-PYGKPVDVWGCGVILFILLSGCLPF----YGTKERLFEGIIKGKYKMNPRQWSHISESAKDLVRRMLMLDPAERITVYEALNHPWLKE--------RDRYAYKIHLPETVEQLRKFNARRKLKG---------------------------
92 PsiBlast_CBE 50.7438%-121 - C1 -3MFU CSKP_HUMAN A:[22-294] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FEDVYELCEVIGKGAFSVVRRCINRETGQQFAVKI--VDVAKFT------SSPGLSTE-------DLKREASICHMLK-HPHIVELLETY-SS-D-G-MLY-MVFEFMDGADLCFEIVK--------------------------------------RADAGFVYSEAVASHYMRQILEALRYCHDNNIIHRDVKPENVLLASK-E-NSA-PVKLGDFGVA-IQL-----GESGLVAGGRVGTPHFMAPEV------VKRE-PYGKPVDVWGCGVILFILLSGCLPF----YGTKERLFEGIIKGKYKMNPRQWSHISESAKDLVRRMLMLDPAERITVYEALNHPWLKE--------RDRYAYKIHLPETVEQLRKFNARRKLKG---------------------------
39 PsiBlast_CBE 50.5842%-132 - C1 -4FG8 KCC1A_HUMAN B:[16-276] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IRDIYDFRDVLGTGAFSEVILAEDKRTQKLVAIKC--IAK-------------------------N---EIAVLHKIK-HPNIVALDDIY-ES-G-G-HLY-LIMQLVSGGELFDRIVE--------------------------------------KGF----YTERDASRLIFQVLDAVKYLHDLGIVHRDLKPENLLYYSL-D-EDS-KIMISDFG-------------GSVLS-TACGTPGYVAPEVL------AQK-PYSKAVDCWSIGVIAYILLCGYPPFYD---ENDAKLFEQILKAEYEFDSPYWDDISDSAKDFIRHLMEKDPEKRFTCEQALQHPWIAG--------DTALDKNIHQSVSEQIKKNFA----------------------------------
104 PsiBlast_CBE 49.0836%-115 - C1 -2V7O KCC2G_HUMAN A:[31-291] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DDYQLFEELGKG-FSVVRRCVKKTPTQEYAAKI--INTKKL---SARDHQ---KLE-------R---EARICRLLK-HPNIVRLHDSI-SE-E-G-FHY-LVFDLVTGGELFEDIVA--------------------------------------REY----YSEADASHCIHQILESVNHIHQHDIVHRDLKPENLLLASK-C-KGA-AVKLADFGLAIEVQ-----GEQQAWF-GFAGTPGYLSPEVL---RK---D-PYGKPVDIWACGVILYILLVGYPPFWD---EDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITADQALKHPWVCQ--------RSTVASMMHRQETVECLRKFNARRKLKG---------------------------
57 PsiBlast_CBE 49.0541%-113 - C1 -4MXA ? A:[27-287] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DRYKGQRVLGKGSFGEVILCKDKITGQECAVKV--ISKRQVKQKTDKES-----LL-------R---EVQLLKQLD-HPNIMKLYEFFEDK-G-Y-Y-Y-LVGEVYTGGELFDEIIS--------------------------------------RKR----FSEVDAARIIRQVLSGITYMHKNKIVHRDLKPENLLLESK-S-KDA-NIRIIDFGLS-THF-----EASKKMK-DKIGTAYYIAPEVL-----HGT---YDEKCDVWSTGVILYILLSGCPPFNG--ANEYDILK-KVEKGKYTFELPQWKKVSESAKDLIRKMLTYVPSMRISARDALDHEWIQT--------YTKEQISVDVPSLDNAILNIRQFQGTQKLAQAALLYMGSKLTSQDETKELTAIFH
86 PsiBlast_CBE 48.9539%-125 - C1 -3Q5I ? A:[38-306] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YFKVRKLGS--YGEVLLCKEKNGHSEKAIKV--IKK------------------KFHEEIYN---EISLLKSLD-HPNIIKLFDVFEDK-K-Y-F-Y-LVTEFYEGGELFEQIIN--------------------------------------RHK----FDECDAANIMKQILSGICYLHKHNIVHRDIKPENILLENK-N-SLL-NIKIVDFGLS-SFF-----SKDYKLR-DRLGTAYYIAPEVL-------KK-KYNEKCDVWSCGVIMYILLCGYPPFGG--QNDQDIIK-KVEKGKYYFDFNDWKNISDEAKELIKLMLTYDYNKRCTAEEALNSRWIKK--------YANNINKSDQKTLCGALSNMRKFEGSQKLAQAAILFIGSKLTTLEERKELTDIFK
64 PsiBlast_CBE 48.8840%-117 - C1 -4WG5 ? A:[26-286] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DRYKGQRVLGKGSFGEVILCKDKITGQECAVKV--ISKRQVKQKTDKES-----LL-------R---EVQLLKQLD-HPNIMKLYEFF-ED-K-G-YFY-LVGEVYTGGELFDEIIS--------------------------------------RKR----FSEVDAARIIRQVLSGITYMHKNKIVHRDLKPENLLLESK-S-KDA-NIRIIDFGLS-THF-----EASKKMK-DKIGTAYYIAPEVL-------HG-TYDEKCDVWSTGVILYILLSGCPPFNG--ANEYDILK-KVEKGKYTFELPQWKKVSESAKDLIRKMLTYVPSMRISARDALDHEWIQT--------YTKEQISVDVPSLDNAILNIRQFQGTQKLAQAALLYMGSKLTSQDETKELTAIFH
136 HHSearch 48.5535%-111 - C1 -3HKO ? A:[17-336] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QGGSLLELQKKYHLKGAIGQGSYGVVRVAIENQTRAIRAIKI--MNKNKIRQ------KDVERIK-------T---EVRLMKKLH-HPNIARLYEVY-ED-E-QYI-C-LVMELCHGGHLLDKLNVFIDDSTGKCAMDVVKTQICPCPECNEEAINGSIFRESLDFV----QREKLISNIMRQIFSALHYLHNQGICHRDIKPENFLFSTN-K--SF-EIKLVDFGLS-KEFYKLNNG---------AGTPYFVAPEVL---NTT-NE-SYGPKCDAWSAGVLLHLLLMGAVPFPG--V-NDADTISQVLNKKLCFENPNYNVLSPLARDLLSNLLNRNVDERFDAMRALQHPWISQ--------FSDKIYKMS----------------------------------------------
43 PsiBlast_CBE 48.4944%-121 - C1 -2JAM KCC1G_HUMAN A:[7-265] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IRKTFIFMEVLGSGAFSEVFLVKQRLTGKLFALKC--IKK-----------S---SLE-------N---EIAVLKKIK-HENIVTLEDIY-ES-TTH-Y-Y-LVMQLVSGGELFDRILE--------------------------------------RGV----YTEKDASLVIQQVLSAVKYLHENGIVHRDLKPENLLYLTP-E-ENS-KIMITDFGLS-K-M-----EQNGIMS-TACGTPGYVAPEVL------AQK-PYSKAVDCWSIGVITYILLCGYPPFYE---ETESKLFEKIKEGYYEFESPFWDDISESAKDFICHLLEKDPNERYTCEKALSHPWIDG--------NTALHRDIYPSVSLQIQKNFAKS--------------------------------
42 PsiBlast_CBE 48.3844%-118 - C1 -2JAM KCC1G_HUMAN B:[7-265] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IRKTFIFMEVLGSGAFSEVFLVKQRLTGKLFALKC--IKK-----------S---SLE-------N---EIAVLKKIK-HENIVTLEDIY-ES-TTH-Y-Y-LVMQLVSGGELFDRILE--------------------------------------RGV----YTEKDASLVIQQVLSAVKYLHENGIVHRDLKPENLLYLTP-E-ENS-KIMITDFGLS-K-M-----EQNGIMS-TACGTPGYVAPEVL------AQK-PYSKAVDCWSIGVITYILLCGYPPFYE---ETESKLFEKIKEGYYEFESPFWDDISESAKDFICHLLEKDPNERYTCEKALSHPWIDG--------NTALHRDIYPSVSLQIQKNFAK---------------------------------
87 PsiBlast_CBE 48.2138%-124 - C1 -4QOX CDPK4_PLAF7 A:[74-338] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VFNEQYKGIKILGKGSFGEVILSRDKHTGHEYAIKV--ISKKHVKRKTDKES-----LL-------R---EVELLKMLD-HINIMKLYEFFEDN-N-Y-Y-Y-LVSDVYTGGELFDEIIS--------------------------------------RKR----FYEIDAARIIKQILSGITYMHKNNVVHRDLKPENILLETKN--EDM-IIKIIDFGLS-THF-----EYS------KIGTAYYIAPDVL-------HG-TYDEKCDIWSCGVILYILLSGCPPFNG--SNEYDILK-KVEAGKYTFDLPQFKKISDKAKDLIKKMLMYTSAVRISARDALEHEWIKM--------MTSKLELSIANIRQFQSTQKLAQAALLYMGSKLTTIDETKELTKIFKKMDKNGDG