@TOME V2.3
(Nov 2016)

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Score:

Alignment:

3D Common Core:

Structural Clustering:

Modeller Result :

Complexes Modeling
Templates Information:
Sequence & Result Tab:

Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : CSF1R_HUMAN: (2015-10-05 )
MGPGVLLLLLVATAWHGQGIPVIEPSVPELVVKPGATVTLRCVGNGSVEWDGPPSPHWTLYSDGSSSILSTNNATFQNTGTYRCTEPGDPLGGSAAIHLYVKDPARPWNVLAQEVVVFEDQDALLPCLLTDPVLEAGVSLVRVRGRPLMRHTNYSFSPWHGFTIHRAKFIQSQDYQCSALMGGRKVMSISIRLKVQKVIPGPPALTLVPAELVRIRGEAAQIVCSASSVDVNFDVFLQHNNTKLAIPQQSDFHNNRYQKVLTLNLDQVDFQHAGNYSCVASNVQGKHSTSMFFRVVESAYLNLSSEQNLIQEVTVGEGLNLKVMVEAYPGLQGFNWTYLGPFSDHQPEPKLANATTKDTYRHTFTLSLPRLKPSEAGRYSFLARNPGGWRALTFELTLRYPPEVSVIWTFINGSGTLLCAASGYPQPNVTWLQCSGHTDRCDEAQVLQVWDDPYPEVLSQEPFHKVTVQSLLTVETLEHNQTYECRAHNSVGSGSWAFIPISAGAHTHPPDEFLFTPVVVACMSIMALLLLLLLLLLYKYKQKPKYQVRWKIIESYEGNSYTFIDPTQLPYNEKWEFPRNNLQFGKTLGAGAFGKVVEATAFGLGKEDAVLKVAVKMLKSTAHADEKEALMSELKIMSHLGQHENIVNLLGACTHGGPVLVITEYCCYGDLLNFLRRKAEAMLGPSLSPGQDPEGGVDYKNIHLEKKYVRRDSGFSSQGVDTYVEMRPVSTSSNDSFSEQDLDKEDGRPLELRDLLHFSSQVAQGMAFLASKNCIHRDVAARNVLLTNGHVAKIGDFGLARDIMNDSNYIVKGNARLPVKWMAPESIFDCVYTVQSDVWSYGILLWEIFSLGLNPYPGILVNSKFYKLVKDGYQMAQPAFAPKNIYSIMQACWALEPTHRPTFQQICSFLQEQAQEDRRERDYTNLPSSSRSGGSGSSSSELEEESSSEHLTCCEQGDIAQPLLQPNNYQFC

Atome Classification :

(64 SA) .........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570-.----------......580.......590.......600.....--..610.........620.......630.......640.......650...-....660.......670.......680.......690.......700.......710.......720.......730.......740.......750---........760.......770.......780.......790.......800.......810.......820.......830.......840.......850.......860.......870.......880.......890.......900.....----..910.......920.......930.......940.......950.......960.......970
(Atome) (Ident) (Tito) (Num) (Ligand) (Uniprot) MGPGVLLLLLVATAWHGQGIPVIEPSVPELVVKPGATVTLRCVGNGSVEWDGPPSPHWTLYSDGSSSILSTNNATFQNTGTYRCTEPGDPLGGSAAIHLYVKDPARPWNVLAQEVVVFEDQDALLPCLLTDPVLEAGVSLVRVRGRPLMRHTNYSFSPWHGFTIHRAKFIQSQDYQCSALMGGRKVMSISIRLKVQKVIPGPPALTLVPAELVRIRGEAAQIVCSASSVDVNFDVFLQHNNTKLAIPQQSDFHNNRYQKVLTLNLDQVDFQHAGNYSCVASNVQGKHSTSMFFRVVESAYLNLSSEQNLIQEVTVGEGLNLKVMVEAYPGLQGFNWTYLGPFSDHQPEPKLANATTKDTYRHTFTLSLPRLKPSEAGRYSFLARNPGGWRALTFELTLRYPPEVSVIWTFINGSGTLLCAASGYPQPNVTWLQCSGHTDRCDEAQVLQVWDDPYPEVLSQEPFHKVTVQSLLTVETLEHNQTYECRAHNSVGSGSWAFIPISAGAHTHPPDEFLFTPVVVACMSIMALLLLLLLLLLYKYKQKPKYQVRWKIIESYEGNSYTFIDPTQLPYN-E----------KWEFPRNNLQFGKTLGAGAFGKVVEATAFGLGKE--DAV--LKVAVKMLKSTAHADEKEALMSELKIMSHLGQHENIVNLLGACTH-GGPVLVITEYCCYGDLLNFLRRKAEAMLGPSLSPGQDPEGGVDYKNIHLEKKYVRRDSGFSSQGVDTYVEMRPVSTSSNDSFSEQDLDKEDGRPLE----LRDLLHFSSQVAQGMAFLASKNCIHRDVAARNVLLTNGHVAKIGDFGLARDIMNDSNYIVKGNARLPVKWMAPESIFDCVYTVQSDVWSYGILLWEIFSLGLNPYPGILVNSKFYKLVKDGYQMAQPAFAPKNIYSIMQACWALEPTHRPTFQQIC----SFLQEQAQEDRRERDYTNLPSSSRSGGSGSSSSELEEESSSEHLTCCEQGDIAQPLLQPNNYQFC
3 PsiBlast_PDB 80.6287%-121 - C7 -4R7H ? A:[14-339] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PKYQVRWKIIESY-----TFIDPTQLPYN-E----------KWEFPRNNLQFGKTLGAGAFGKVVEATAFGLGKE--DAV--LKVAVKMLKSTAHADEKEALMSELKIMSHLGQHENIVNLLGACTH-GGPVLVITEYCTYGDLLNFLRRKAEAMLGPSL-----------------------------------------------------------GRPLE----LRDLLHFSSQVAQGMAFLASKNCIHRDVAARNVLLTNGHVAKIGDFGLARDIMNDSNYIVKGNARLPVKWMAPESIFDSVYTVQSDVWSYGILLWEIFSLGLNPYPGILVNSKFYKLVKDGYQMAQPAFAPKNIYSIMQACWALEPTHRPTFQQIT----SFLQEQAQ---------------------------------------------------------
4 PsiBlast_PDB 78.7587%-122 - C7 -4R7I ? A:[37-338] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TQLPYN-E----------KWEFPRNNLQFGKTLGAGAFGKVVEATAFGLGKE--DAV--LKVAVKMLKSTAHADEKEALMSELKIMSHLGQHENIVNLLGACTH-GGPVLVITEYCTYGDLLNFLRRKAEAMLGPSLS----------------------------------------------------------GRPLE----LRDLLHFSSQVAQGMAFLASKNCIHRDVAARNVLLTNGHVAKIGDFGLARDIMNDSNYIVKGNARLPVKWMAPESIFDSVYTVQSDVWSYGILLWEIFSLGLNPYPGILVNSKFYKLVKDGYQMAQPAFAPKNIYSIMQACWALEPTHRPTFQQIT----SFLQEQA----------------------------------------------------------
6 PsiBlast_PDB 78.5082%-122 - C7 -2I0Y ? A:[14-329] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VRWKIIESYE--SYTFI---------E----------KWEFPRNNLQFGKTLGAGAFGKVVEATAFGLGKE--DAV--LKVAVKMLKSTAHADEKEALMSELKIMSHLGQHENIVNLLGACTH-GGPVLVITEYCCYGDLLNFLRRKR------------------------------------------------------------Q---------LS----SRDLLHFSSQVAQGMAFLASKNCIHRDVAARNVLLTNGHVAKIGDFGLARDIMNDSNYIVKG-ARLPVKWMAPESIFDCVYTVQSDVWSYGILLWEIFSLGLNPYPGILVNSKFYKLVKDGYQMAQPAFAPKNIYSIMQACWALEPTHRPTFQQIC----SFLQEQAQE--------------------------------------------------------
5 PsiBlast_PDB 77.7982%-115 - C7 -2I0V A:[10-329] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PKYQVRWKIIESYEGNSYTFIDPTQLPYN-E----------KWEFPRNNLQFGKTLGAGAFGKVVEATAFGLGKE--DAV--LKVAVKMLKSTAHADEKEALMSELKIMSHLGQHENIVNLLGACTH-GGPVLVITEYCCYGDLLNFLRRKR------------------------------------------------------------Q---------LS----SRDLLHFSSQVAQGMAFLASKNCIHRDVAARNVLLTNGHVAKIGDFGLARDIMNDSNYIVKG-ARLPVKWMAPESIFDCVYTVQSDVWSYGILLWEIFSLGLNPYPGILVNSKFYKLVKDGYQMAQPAFAPKNIYSIMQACWALEPTHRPTFQQIC----SFLQEQAQE--------------------------------------------------------
7 PsiBlast_PDB 77.4281%-110 - C7 -2I1M A:[13-332] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QVRWKIIESY--NSYTFIDPTQLPYN-E----------KWEFPRNNLQFGKTLGAGAFGKVVEATAFGLGKE--DAV--LKVAVKMLKSTAHADEKEALMSELKIMSHLGQHENIVNLLGACTH-GGPVLVITEYCCYGDLLNFLRRKSRVL------------------------------------------ETD-------STAST-----------------RDLLHFSSQVAQGMAFLASKNCIHRDVAARNVLLTNGHVAKIGDFGLARDIMNDSNYIVKGNARLPVKWMAPESIFDCVYTVQSDVWSYGILLWEIFSLGLNPYPGILVNSKFYKLVKDGYQMAQPAFAPKNIYSIMQACWALEPTHRPTFQQIC----SFLQEQAQEDRRER---------------------------------------------------
2 PsiBlast_PDB 76.7487%-120 - C7 -4HW7 A:[36-338] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PTQLPYN-E----------KWEFPRNNLQFGKTLGAGAFGKVVEATAFGLGKE--DAV--LKVAVKMLKSTAHADEKEALMSELKIMSHLGQHENIVNLLGACTH-GGPVLVITEYCTYGDLLNFLRRKAEAMLGPS------------------------------------------------------------GRPLE----LRDLLHFSSQVAQGMAFLASKNCIHRDVAARNVLLTNGHVAKIGDFGLARDIMNDSNYIVKGNARLPVKWMAPESIFDSVYTVQSDVWSYGILLWEIFSLGLNPYPGILVNSKFYKLVKDGYQMAQPAFAPKNIYSIMQACWALEPTHRPTFQQIT----SFLQEQA----------------------------------------------------------
11 PsiBlast_PDB 73.2860%-106 - C7 -4HVS A:[10-331] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PMYEVQWKVVEESNGNNYSYIDPTQLPYD-H----------KWEFPRNRLSFGKTLGAGAFGKVVEATAQGLIKS--DAA--MTVAVKMLKPSAHSTEREALMSELKVLSYLGNHENIVNLLGACTH-GGPTLVITEYCCYGDLLNFLRRK--------------------------------RDSFHSS-------DTSPASM------------EDDENALD----LEDLLSFSYQVAKGMAFLASKNCIHRDLAARNILLTHGRITKICDFGLARDIKNDSNYVDKGNARLPVKWMAPESIFNSVYTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMSSPEHAPAEMYDIMKTCWDADPDKRPTFKQIV----QDIEKQISES-------------------------------------------------------
25 PsiBlast_CBE 73.0147%-120 - C7 -1Y6B A:[14-363] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RLPYDAS---KWEFPRDRLKLGKPLGRG--GQVIEADAFGIDKT--ATC--RTVAVKMLK--ATHSEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVIVEFCKFGNLSTYLRSKRNEFV-PY--------------------------------------------------------------FLT----LEHLICYSFQVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDF--------------------PLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTFSELVEHLGNLLQANA----------------------------------------------------------
12 PsiBlast_PDB 71.8149%-119 - C7 -4RT7 A:[56-407] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YD-L----------KWEFPRENLEFGKVLGSGAFGKVMNATAYGIS----GVS--IQVAVKMLK---DSSEREALMSELKMMTQLGSHENIVNLLGACTL-SGPIYLIFEYCCYGDLLNYLRSKR------------------------------------------------------------------------NVLTFEDLLCFAYQVAKGMEFLEFKSCVHRDLAARNVLVTHGKVVKICDFGLARDIMSDSNYVVRGNARLPVKWMAPESLFEGIYTIKSDVWSYGILLWEIFSLGVNPYPGIPVDANFYKLIQNGFKMDQPFYATEEIYIIMQSCWAFDSRKRPSFPNLT----SFLGCQLA-DA------------------------------------------------------
26 PsiBlast_CBE 71.4347%-123 - C7 -1Y6A A:[15-362] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LPYDAS----KWEFPRDRLKLGKPLGR----QVIEADAFGIDKT--ATC--RTVAVKML----THSEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVIVEFCKFGNLSTYLRSKRNEFV-PY----------------------------------------------------------D---FLT----LEHLICYSFQVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDF--------------------PLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTFSELVEHLGNLLQAN-----------------------------------------------------------
28 PsiBlast_CBE 71.2548%-112 - C7 -3VHE A:[9-359] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RLPYDAS----------KWEFPRDRLKLGKPLGRGAFGQVIEADAFGIDKT--ATC--RTVAVKMLKEGATHSEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVIVEFCKFGNLSTYLRSKRNEFV-PYK-----------------------------------------------------DLYKD---FLT----LEHLICYSFQVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDFGLARDIYKDPDYVRK--ARLPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTFSELVEHLGNLLQANAQ---------------------------------------------------------
49 PsiBlast_CBE 71.1046%-124 - C7 -3B8R B:[7-302] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PYDAS----------KWEFPRDRLKLGKPLGR---GQVIEADAFGIDKT--ATC--RTVAVKML---ATHSEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVITEFCKFGNLSTYLRSKRNEFVPYK--------------------------------------------------------YKDF---LT----LEHLICYSFQVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDFGL-----------------LPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTFSELVEHLGNLLQA------------------------------------------------------------
64 PsiBlast_CBE 71.0544%-126 - C7 -4WUN B:[10-300] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELPED-P----------RWELPRDRLVLGKPLGEGAFGQVVLAEAIGL---KPNRV--TKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLQARRPP----------------------------------------------------------Q---------LS----SKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGL-----------------LPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPV-EELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLV----EDLDRIVALTS------------------------------------------------------
54 PsiBlast_CBE 70.9846%-127 - C7 -2QU6 B:[8-301] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YDAS----------KWEFPRDRLKLGKPLGR----QVIEADAFGIDKT--ATC--RTVAVKMLKEGATHSEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVITEFCKFGNLSTYLRSKRNEFVP-------------------------------------------------------------F---LT----LEHLICYSFQVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDF-------------------LPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTFSELVEHLGNLLQ-------------------------------------------------------------
50 PsiBlast_CBE 70.6946%-118 - C7 -3B8R VGFR2_HUMAN A:[5-308] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RLPYDAS----------KWEFPRDRLKLGKPLG-----QVIEADAFGIDKT--ATC--RTVAVKMLKEGATHSEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVITEFCKFGNLSTYLRSKRNEFVPYKVAP--------------------------------------------------EDLYKDF---LT----LEHLICYSFQVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDFGL-----------------LPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTFSELVEHLGNLLQANAQQDRHHHHHH------------------------------------------------
27 PsiBlast_CBE 70.6047%-107 - C7 -3VHK A:[11-365] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D-EHCERLPYDASKWEFPRDRLKLGKPLGRGAFGQVIEADAFGIDKT--ATC--RTVAVKMLKEGATHSEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVIVEFCKFGNLSTYLRSKRNEFV-PYK-------------------------------------------------------YKD---FLT----LEHLICYSFQVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDFGLARDIYKDPDYVRK--ARLPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTFSELVEHLGNLLQANA----------------------------------------------------------
60 PsiBlast_CBE 70.4345%-113 - C7 -2P2I VGFR2_HUMAN A:[5-308] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RLPYDAS----------KWEFPRDRLKLGKPLGRGAFGQVIEADAFGID-----TC--RTVAVKML----THSEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVIVEFCKFGNLSTYLRSKRNEFVPYKVAP--------------------------------------------------EDLYKDF---LT----LEHLICYSFQVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDFGLA----------------LPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTFSELVEHLGNLLQANAQQDRHHHHHH------------------------------------------------
44 PsiBlast_CBE 70.4246%-123 - C7 -3CPB B:[6-301] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LPYDAS----------KWEFPRDRLKLGKPLG-----QVIEADAFGIDKT--ATC--RTVAVKML---ATHSEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVITEFCKFGNLSTYLRSKRNEFVPYK---------------------------------------------------------KDF---LT----LEHLICYSFQVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDFG------------------LPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTFSELVEHLGNLLQ-------------------------------------------------------------
52 PsiBlast_CBE 70.3846%-114 - C7 -3B8Q VGFR2_HUMAN A:[5-308] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RLPYDAS----------KWEFPRDRLKLGKPLGRGAFGQVIEADAFGIDKT--ATC--RTVAVKMLKEGATHSEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVITEFCKFGNLSTYLRSKRNEFVPYKVAP--------------------------------------------------EDLYKDF---LT----LEHLICYSFQVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDF-------------------LPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTFSELVEHLGNLLQANAQQDRHHHHHH------------------------------------------------
72 PsiBlast_CBE 70.3544%-116 - C7 -4V05 FGFR1_HUMAN A:[8-298] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELPED-P----------RWELPRDRLVLGKPLGEGAFGQVVLAEAIGLDKDKPNRV--TKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLQARRPPG-----------E--------------------------------------------EQ---------LS----SKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLAR----IDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPV-EELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLV----EDLDRIVALTSNQE---------------------------------------------------
46 PsiBlast_CBE 70.3146%-123 - C7 -3CP9 B:[5-301] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RLPYDAS----------KWEFPRDRLKLGKPLGRG--GQVIEADAFGIDKT--ATC--RTVAVKML---ATHSEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVITEFCKFGNLSTYLRSKRNEFVPYKV--------------------------------------------------------KDF---LT----LEHLICYSFQVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDFGL-----------------LPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTFSELVEHLGNLLQ-------------------------------------------------------------
40 PsiBlast_CBE 70.1846%-119 - C7 -3WZD A:[7-304] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LPYDAS----------KWEFPRDRLKLGKPLG----GQVIEADAFGIDKT--ATC--RTVAVKMLKEGATHSEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVIVEFCKFGNLSTYLRSKRNEFVPYKVAP--------------------------------------------------EDLYKD---FLT----LEHLICYSFQVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDFGLA----------------LPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTFSELVEHLGNLLQAN-----------------------------------------------------------
43 PsiBlast_CBE 70.1146%-119 - C7 -3CPC VGFR2_HUMAN A:[6-308] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LPYDAS----------KWEFPRDRLKLGKPL------QVIEADAFGIDKT--ATC--RTVAVKMLKEGATHSEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVITEFCKFGNLSTYLRSKRNEFVPYKVAP--------------------------------------------------EDLYKDF---LT----LEHLICYSFQVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDF-------------------LPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTFSELVEHLGNLLQANAQQDRHHHHHH------------------------------------------------
22 PsiBlast_CBE 70.1154%-116 - C7 -4XUF B:[3-293] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KWEFPRENLEFGKVLGSGAFGKVMNATAYGISKT--GVS--IQVAVKMLKEKADSSEREALMSELKMMTQLGSHENIVNLLGACTL-SGPIYLIFEYCCYGDLLNYLRSKR--------------------------------------------------------------------NVLT----FEDLLCFAYQVAKGMEFLEFKSCVHRDLAARNVLVTHGKVVKICDFGLARDIMSDSNYVVRGNARLPVKWMAPESLFEGIYTIKSDVWSYGILLWEIFSLGVNPYPGIPVDANFYKLIQNGFKMDQPFYATEEIYIIMQSCWAFDSRKRPSFPNLT----SFLGCQ-----------------------------------------------------------
45 PsiBlast_CBE 70.0146%-118 - C7 -3CPB VGFR2_HUMAN A:[5-308] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RLPYDAS----------KWEFPRDRLKLGKPL------QVIEADAFGIDKT--ATC--RTVAVKMLKEGATHSEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVITEFCKFGNLSTYLRSKRNEFVPYKVAP--------------------------------------------------EDLYKDF---LT----LEHLICYSFQVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDF-------------------LPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTFSELVEHLGNLLQANAQQDRHHHHHH------------------------------------------------
70 PsiBlast_CBE 69.9244%-119 - C7 -5AM6 B:[9-299] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELPED-P----------RWELPRDRLVLGKPLGEGAFGQVVLAEAIGLDKDKPNRV--TKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLQARRPP------------E--------------------------------------------EQ---------LS----SKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLAR-------------GRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPV-EELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLV----EDLDRIVALTS------------------------------------------------------
69 PsiBlast_CBE 69.8644%-114 - C7 -3RHX FGFR1_HUMAN A:[5-295] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELPED-P----------RWELPRDRLVLGKPLGEGAFGQVVLAEAIGLDKDKPNRV--TKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLQARRPP------------E--------------------------------------------EQ---------LS----SKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPV-EELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLV----EDLDRIVALTSNQ----------------------------------------------------
57 PsiBlast_CBE 69.8545%-124 - C7 -3EFL B:[7-301] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PYDAS----------KWEFPRDRLKLGKPLGRG--GQVIEADAFGIDKT--ATC--RTVAVKML---ATHSEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVIVEFCKFGNLSTYLRSKRNEFVPYK-----------------------------------------------------------F---LT----LEHLICYSFQVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDFG------------------LPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTFSELVEHLGNLLQ-------------------------------------------------------------
62 PsiBlast_CBE 69.7044%-114 - C7 -4ZSA B:[7-297] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELPED-P----------RWELPRDRLVLGKPLGEGAFGQVVLAEAIGLDKDKPNRV--TKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLQARRPP------------E--------------------------------------------EQ---------LS----SKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGL------IDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPV-EELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLV----EDLDRIVALT-------------------------------------------------------
51 PsiBlast_CBE 69.6446%-118 - C7 -3B8Q B:[6-302] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LPYDAS----------KWEFPRDRLKLGKPLGRG--GQVIEADAFGIDKT--ATC--RTVAVKMLKEGATHSEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVITEFCKFGNLSTYLRSKRNEFVPYK--------------------------------------------------------YKDF---LT----LEHLICYSFQVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDFG------------------LPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTFSELVEHLGNLLQA------------------------------------------------------------
61 PsiBlast_CBE 69.6244%-118 - C7 -4K33 A:[25-314] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LPAD-P----------KWELSRARLTLGKPLGEGAFGQVVMAEAIGIDKD--RAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQ-GGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTS------------------------------------------------EQ---------LT----FKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKETTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPV-EELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLV----EDLDRVLTVT-------------------------------------------------------
76 PsiBlast_CBE 69.5044%-118 - C7 -4V01 FGFR1_HUMAN A:[9-298] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LPED-P----------RWELPRDRLVLGKPLG----GQVVLAEAIGLD--KPNRV--TKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLQARRPP----------------------------------------------------------Q---------LS----SKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADF--------IDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPV-EELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLV----EDLDRIVALTSNQE---------------------------------------------------
42 PsiBlast_CBE 69.4946%-122 - C7 -3CPC B:[6-301] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LPYDAS----------KWEFPRDRLKLGKPLG-----QVIEADAFGIDKT--ATC--RTVAVKML---ATHSEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVITEFCKFGNLSTYLRSKRNEFVP----------------------------------------------------------YKDF---LT----LEHLICYSFQVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDFG------------------LPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTFSELVEHLGNLLQ-------------------------------------------------------------
47 PsiBlast_CBE 69.4646%-115 - C7 -3CP9 VGFR2_HUMAN A:[5-308] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RLPYDAS----------KWEFPRDRLKLGKPL------QVIEADAFGIDKT--ATC--RTVAVKMLKEGATHSEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVITEFCKFGNLSTYLRSKRNEFVPYKVAP--------------------------------------------------EDLYKDF---LT----LEHLICYSFQVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDFG------------------LPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTFSELVEHLGNLLQANAQQDRHHHHHH------------------------------------------------
67 PsiBlast_CBE 69.3844%-111 - C7 -5A4C ? A:[6-296] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELPED-P----------RWELPRDRLVLGKPLGE--FGQVVLAEAIGLDKDKPNRV--TKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLQARRPPGLEYSYNPSHNPE--------------------------------------------EQ---------LS----SKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGL------IDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPV-EELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLV----EDLDRIVALTSNQE---------------------------------------------------
65 PsiBlast_CBE 69.3544%-117 - C7 -4WUN FGFR1_HUMAN A:[11-300] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LPED-P----------RWELPRDRLVLGKPLGEGAFGQVVLAEAIGLDKDKPNRV--TKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLQARRPP-LEYSYNPSHNPE--------------------------------------------EQ---------LS----SKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFG------------------LPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPV-EELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLV----EDLDRIVALTSNQE---------------------------------------------------
71 PsiBlast_CBE 69.3144%-115 - C7 -5AM6 FGFR1_HUMAN A:[9-299] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELPED-P----------RWELPRDRLVLGKPLGE---GQVVLAEAIGLDKDKPNRV--TKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQ-DGPLYVIVEYASKGNLREYLQARRPPG-----------E--------------------------------------------EQ---------LS----SKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPV-EELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLV----EDLDRIVALTSNQE---------------------------------------------------
58 PsiBlast_CBE 69.2645%-110 - C7 -3EFL VGFR2_HUMAN A:[5-308] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RLPYDAS----------KWEFPRDRLKLGKPLGRG--GQVIEADAFGID-----TC--RTVAVKMLKE--THSEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVIVEFCKFGNLSTYLRSKRNEFVPYKVAP--------------------------------------------------EDLYKDF---LT----LEHLICYSFQVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDFG-------------------PLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTFSELVEHLGNLLQANAQQDRHHHHHH------------------------------------------------
55 PsiBlast_CBE 69.1146%-114 - C7 -2QU5 A:[5-306] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RLPYDAS----------KWEFPRDRLKLGKPLGRGAFGQVIEADAFGIDKT--ATC--RTVAVKMLKEGATHSEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVITEFCKFGNLSTYLRSKRNEFVPYKVAP--------------------------------------------------EDLYKDF---LT----LEHLICYSFQVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDFGLA-------------DARLPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTFSELVEHLGNLLQANAQQ--------------------------------------------------------
29 PsiBlast_CBE 69.0146%-105 - C7 -3U6J A:[5-308] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RLPYDAS----------KWEFPRDRLKLGKPLGRGAFGQVIEADAFGID----ATC--RTVAV