@TOME V2.3
(Nov 2016)

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3D Common Core:

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Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : DAPK2_HUMAN: (2015-10-06 )
MFQASMRSPNMEPFKQQKVEDFYDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGVSREEIEREVSILRQVLHHNVITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEEATSFIKQILDGVNYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIEDGVEFKNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANITAVSYDFDEEFFSQTSELAKDFIRKLLVKETRKRLTIQEALRHPWITPVDNQQAMVRRESVVNLENFRKQYVRRRWKLSFSIVSLCNHLTRSLMKKVHLRPDEDLRNCESDTEEDIARRKALHPRRRSSTS

Atome Classification :

(57 SA) .........10....-....20....----.--..--.30........40........50........60.....-.--..70........80.-..-.....90........100.......110..-.....--.120-.........130.......140.......150.....--.--.160.......170......-.-180..-......190.......------200........210.......220......---.230..-.....240.......250.......260.......270.......280.......290----..-...-..300-........310.......320.....---..330.......340.......350.......360.......370
(Atome) (Ident) (Tito) (Num) (Ligand) (Uniprot) MFQASMRSPNMEPFK-QQKVEDFYDI----G--EE--LGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGV-S--REEIEREVSILRQVL-HH-NVITLHDVYENRTDVVLILELVSGGEL-FD-FLAQK--ES---LSEEEATSFIKQILDGVNYLHTKKIAHFDLKPENIML--L--DKNIPIPHIKLIDFGLAHEI-E-DG-VE-FKNIFGTPEFVAPEIV------N-YEPLGLEADMWSIGVITYILLSGASPFL---GDTKQE-TLANITAVSYDFDEEFFSQTSELAKDFIRKLLVKETRKRLTIQEALRHPWITPVDNQQ----AM-VRR-ESVV--NLENFRKQYVRRRWKLSFSIVSLCNH---LTRSLMKKVHLRPDEDLRNCESDTEEDIARRKALHPRRRSSTS
26 PsiBlast_CBE 89.0699%-111 - C1 -2CKE DAPK2_HUMAN B:[3-302] -----------EPFK-QQKVEDFYDI----G--EE--LGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGV-S--REEIEREVSILRQVL-HH-NVITLHDVYENRTDVVLILELVSGGEL-FD-FLAQK--ES---LSEEEATSFIKQILDGVNYLHTKKIAHFDLKPENIML--L--DKNIPIPHIKLIDFGLAHEI-E-DG-VE-FKNIFGTPEFVAPEIV------N-YEPLGLEADMWSIGVITYILLSGASPFL---GDTKQE-TLANITSVSYDFDEEFFSHTSELAKDFIRKLLVKETRKRLTIQEALRHPWITPVDNQQ----AM-VRR-ESVV--NLENFRKQYV--------------------------------------------------------------
2 PsiBlast_PDB 88.2397%-104 - C1 -2YAA DAPK2_MOUSE A:[3-302] -----------ETFK-QQKVEDFYDI----G--EE--LGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGV-C--REEIEREVSILRQVL-HP-NIITLHDVYENRTDVVLILELVSGGEL-FD-FLAQK--ES---LSEEEATSFIKQILDGVNYLHTKKIAHFDLKPENIML--L--DKNIPIPHIKLIDFGLAHEI-E-DG-VE-FKNIFGTPEFVAPEIV------N-YEPLGLEADMWSIGVITYILLSGASPFL---GDTKQE-TLANITAVSYDFDEEFFSQTSELAKDFIRKLLVKETRKRLTIQEALRHPWITPVDTQQ----AM-VRR-ESVV--NLENFKKQYV--------------------------------------------------------------
5 PsiBlast_PDB 87.9499%-109 - C1 -2CKE DAPK2_HUMAN A:[2-302] ----------MEPFK-QQKVEDFYDI----G--EE--LGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGV-S--REEIEREVSILRQVL-HH-NVITLHDVYENRTDVVLILELVSGGEL-FD-FLAQK--ES---LSEEEATSFIKQILDGVNYLHTKKIAHFDLKPENIML--L--DKNIPIPHIKLIDFGLAHEI-E-DG-VE-FKNIFGTPEFVAPEIV------N-YEPLGLEADMWSIGVITYILLSGASPFL---GDTKQE-TLANITSVSYDFDEEFFSHTSELAKDFIRKLLVKETRKRLTIQEALRHPWITPVDNQQ----AM-VRR-ESVV--NLENFRKQYV--------------------------------------------------------------
22 PsiBlast_CBE 87.8597%-107 - C1 -2YAA DAPK2_MOUSE B:[4-302] ------------TFK-QQKVEDFYDI----G--EE--LGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGV-C--REEIEREVSILRQVL-HP-NIITLHDVYENRTDVVLILELVSGGEL-FD-FLAQK--ES---LSEEEATSFIKQILDGVNYLHTKKIAHFDLKPENIML--L--DKNIPIPHIKLIDFGLAHEI-E-DG-VE-FKNIFGTPEFVAPEIV------N-YEPLGLEADMWSIGVITYILLSGASPFL---GDTKQE-TLANITAVSYDFDEEFFSQTSELAKDFIRKLLVKETRKRLTIQEALRHPWITPVDTQQ----AM-VRR-ESVV--NLENFKKQYV--------------------------------------------------------------
25 PsiBlast_CBE 85.9899%-109 - C1 -2CKE DAPK2_HUMAN C:[3-302] -----------EPFK-QQKVEDFYDI----G--EE--LGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGV-S--REEIEREVSILRQVL-HH-NVITLHDVYENRTDVVLILELVSGGEL-FD-FLAQK--ES---LSEEEATSFIKQILDGVNYLHTKKIAHFDLKPENIML--L--DKNIPIPHIKLIDFGLAHEI-E-DG-VE-FKNIFGTPEFVAPEIV------N-YEPLGLEADMWSIGVITYILLSGASPFL---GDTKQE-TLANITSVSYDFDEEFFSHTSELAKDFIRKLLVKETRKRLTIQEALRHPWITPVDNQQ----AM-VRR-ESVV--NLENFRKQYV--------------------------------------------------------------
24 PsiBlast_CBE 85.6099%-107 - C1 -2CKE DAPK2_HUMAN D:[3-302] -----------EPFK-QQKVEDFYDI----G--EE--LGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGV-S--REEIEREVSILRQVL-HH-NVITLHDVYENRTDVVLILELVSGGEL-FD-FLAQK--ES---LSEEEATSFIKQILDGVNYLHTKKIAHFDLKPENIML--L--DKNIPIPHIKLIDFGLAHEI-E-DG-VE-FKNIFGTPEFVAPEIV------N-YEPLGLEADMWSIGVITYILLSGASPFL---GDTKQE-TLANITSVSYDFDEEFFSHTSELAKDFIRKLLVKETRKRLTIQEALRHPWITPVDNQQ----AM-VRR-ESVV--NLENFRKQYV--------------------------------------------------------------
119 HHSearch 80.0975%-100 - C1 -2Y0A DAPK1_HUMAN A:[3-302] ------------VFR-QENVDDYYDT----G--EE--LGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRRGV-S--REDIEREVSILKEIQ-HP-NVITLHEVYENKTDVILILELVAGGEL-FD-FLAEK--ES---LTEEEATEFLKQILNGVYYLHSLQIAHFDLKPENIML--L--DRNVPKPRIKIIDFGLAHKI-D-FG-NE-FKNIFGTPEFVAPEIV------N-YEPLGLEADMWSIGVITYILLSGASPFL---GDTKQE-TLANVSAVNYEFEDEYFSNTSALAKDFIRRLLVKDPKKRMTIQDSLQHPWIKPKDTQQ----AL-SRK-ASAV--NMEKFKKFAAR-------------------------------------------------------------
14 PsiBlast_PDB 79.8875% -97 - C1 -2W4K DAPK1_HUMAN A:[2-302] -----------TVFR-QENVDDYYDT----G--EE--LGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRRGV-S--REDIEREVSILKEIQ-HP-NVITLHEVYENKTDVILILELVAGGEL-FD-FLAEK--ES---LTEEEATEFLKQILNGVYYLHSLQIAHFDLKPENIML--L--DRNVPKPRIKIIDFGLAHKI-D-FG-NE-FKNIFGTPEFVAPEIV------N-YEPLGLEADMWSIGVITYILLSGASPFL---GDTKQE-TLANVSAVNYEFEDEYFSNTSALAKDFIRRLLVKDPKKRMTIQDSLQHPWIKPKDTQQ----AL-SRK-ASAV--NMEKFKKFAAR-------------------------------------------------------------
16 PsiBlast_PDB 79.0277%-102 - C1 -2Y0A DAPK1_HUMAN A:[4-294] -------------FR-QENVDDYYDT----G--EE--LGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRRGV-S--REDIEREVSILKEIQ-HP-NVITLHEVYENKTDVILILELVAGGEL-FD-FLAEK--ES---LTEEEATEFLKQILNGVYYLHSLQIAHFDLKPENIML--L--DRNVPKPRIKIIDFGLAHKI-D-FG-NE-FKNIFGTPEFVAPEIV------N-YEPLGLEADMWSIGVITYILLSGASPFL---GDTKQE-TLANVSAVNYEFEDEYFSNTSALAKDFIRRLLVKDPKKRMTIQDSLQHPWIKPKDTQQ----AL-SRK-ASAV--NMEKFKKFAAR-------------------------------------------------------------
18 PsiBlast_PDB 78.9877%-109 - C1 -2YAK DAPK1_HUMAN A:[2-278] -----------TVFR-QENVDDYYDT----G--EE--LGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRRGV-S--REDIEREVSILKEIQ-HP-NVITLHEVYENKTDVILILELVAGGEL-FD-FLAEK--ES---LTEEEATEFLKQILNGVYYLHSLQIAHFDLKPENIML--L--DRNVPKPRIKIIDFGLAHKI-D-FG-NE-FKNIFGTPEFVAPEIV------N-YEPLGLEADMWSIGVITYILLSGASPFL---GDTKQE-TLANVSAVNYEFEDEYFSNTSALAKDFIRRLLVKDPKKRMTIQDSLQHPWIKPK---------------------------------------------------------------------------------------------
10 PsiBlast_PDB 76.7772% -97 - C1 -2XUU DAPK1_HUMAN A:[2-302] -----------TVFR-QENVDDYYDT----G--EE--LGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRRGV-S--REDIEREVSILKEIQ-HP-NVITLHEVYENKTDVILILELVAGGEL-FD-FLAEK--ES---LTEEEATEFLKQILNGVYYLHSLQIAHFDLKPENIML--L--DRNVPKPRIKIIDFGLAHKI-D-FG-NE-FKNIFGTPAFVAPEIV------N-YEPLGLEADMWSIGVITYILLSGASPFL---GDTKQE-TLANVSAVNYEFEDEYFSNTSALAKDFIRRLLVKDPKKRMTIQDSLQHPWIKPKDTQQ----AL-SRK-ASAV--NMEKFKKFAAR-------------------------------------------------------------
13 PsiBlast_PDB 76.7472% -95 - C1 -4B4L DAPK1_HUMAN A:[7-305] --------------R-QENVDDYYDT----G--EE--LGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRRGV-S--REDIEREVSILKEIQ-HP-NVITLHEVYENKTDVILILELVAGGEL-FD-FLAEK--ES---LTEEEATEFLKQILNGVYYLHSLQIAHFDLKPENIML--L--DRNVPKPRIKIIDFGLAHKI-D-FG-NE-FKNIFGTPEFVAPEIV------N-YEPLGLEADMWSIGVITYILLSGASPFL---GDTKQE-TLANVSAVNYEFEDEYFSNTSALAKDFIRRLLVKDPKKRMTIQDSLQHPWIKPKDTQQ----AL-SRK-ASAV--NMEKFKKFAAAK------------------------------------------------------------
17 PsiBlast_PDB 76.7377%-106 - C1 -4TXC DAPK1_HUMAN A:[21-296] -----------TVFR-QENVDDYYDT----G--EE--LGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRRGV-S--REDIEREVSILKEIQ-HP-NVITLHEVYENKTDVILILELVAGGEL-FD-FLAEK--ES---LTEEEATEFLKQILNGVYYLHSLQIAHFDLKPENIML--L--DRNVPKPRIKIIDFGLAHKI-D-FG-NE-FKNIFGTPEFVAPEIV------N-YEPLGLEADMWSIGVITYILLSGASPFL---GDTKQE-TLANVSAVNYEFEDEYFSNTSALAKDFIRRLLVKDPKKRMTIQDSLQHPWIKP----------------------------------------------------------------------------------------------
12 PsiBlast_PDB 76.5773% -98 - C1 -4UV0 ? A:[5-304] ------------VFR-QENVDDYYDT----G--EE--LGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRRGV-S--REDIEREVSILKEIQ-HP-NVITLHEVYENKTDVILILELVAGGEL-FD-FLAEK--ES---LTEEEATEFLKQILNGVYYLHSLQIAHFDLKPENIML--L--DRNVPKPRIKIIDFGLAHKI-D-FG-NE-FKNIFGTPEFVAPEIV------N-YEPLGLEADMWSIGVITYILLSGASPFL---GDTKQE-TLANVSAVNYEFEDEYFSNTSALAKDFIRRLLVKDPKKRMTIQDSLQHPWIKPKDTQQ----AL-SRK-ACAV--NMEKFKKFAAR-------------------------------------------------------------
41 PsiBlast_CBE 75.1378%-109 - C1 -1WVY DAPK1_HUMAN A:[4-276] -------------FR-QENVDDYYDT----G--EE--LGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRRGV-S--REDIEREVSILKEIQ-HP-NVITLHEVYENKTDVILILELVAGGEL-FD-FLAEK--ES---LTEEEATEFLKQILNGVYYLHSLQIAHFDLKPENIML--L--DRNVPKPRIKIIDFGLAHKI-D-FG-NE-FKNIFGTPEFVAPEIV------N-YEPLGLEADMWSIGVITYILLSGASPFL---GDTKQE-TLANVSAVNYEFEDEYFSNTSALAKDFIRRLLVKDPKKRMTIQDSLQHPWIK-----------------------------------------------------------------------------------------------
40 PsiBlast_CBE 74.8578%-105 - C1 -2W4J DAPK1_HUMAN A:[2-277] -----------TVFR-QENVDDYYDT----G--EE--LGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRRGV-S--REDIEREVSILKEIQ-HP-NVITLHEVYENKTDVILILELVAGGEL-FD-FLAEK--ES---LTEEEATEFLKQILNGVYYLHSLQIAHFDLKPENIML--L--DRNVPKPRIKIIDFGLAHKI-D-FG-NE-FKNIFGTPEFVAPEIV------N-YEPLGLEADMWSIGVITYILLSGASPFL---GDTKQE-TLANVSAVNYEFEDEYFSNTSALAKDFIRRLLVKDPKKRMTIQDSLQHPWIKP----------------------------------------------------------------------------------------------
38 PsiBlast_CBE 71.1877%-129 - C1 -3ZXT DAPK1_HUMAN D:[7-276] -----------------ENVDDYYDT----G--EE--LGSGQFAVVKKCREKSTGLQYAAKFI-----------V-S--REDIEREVSILKEIQ-HP-NVITLHEVYENKTDVILILELVAGGEL-FD-FLAE---------TEEEATEFLKQILNGVYYLHSLQIAHFDLKPENIML--L--DRNVPKPRIKIIDFGLAHKI-D-------------TPEFVAPEIV------N-YEPLGLEADMWSIGVITYILLSGASPFL---GDTKQE-TLANVSAVNYEFEDEYFSNTSALAKDFIRRLLVKDPKKRMTIQDSLQHPWIK-----------------------------------------------------------------------------------------------
39 PsiBlast_CBE 67.8577%-117 - C1 -3ZXT DAPK1_HUMAN C:[5-276] --------------R-QENVDDYYDT----G--EE--LG--QFAVVKKCREKSTGLQYAAKFIKKRRTKSSRRGV-S--REDIEREVSILKEIQ-HP-NVITLHEVYENKTDVILILELVAGGEL-FD-FLAEK--ES---LTEEEATEFLKQILNGVYYLHSLQIAHFDLKPENIML--L--DRNVPKPRIKIIDFGLAHKI-D--------------PEFVAPEIV------N-YEPLGLEADMWSIGVITYILLSGASPFL---GDTKQE-TLANVSAVNYEFEDEYFSNTSALAKDFIRRLLVKDPKKRMTIQDSLQHPWIK-----------------------------------------------------------------------------------------------
20 PsiBlast_PDB 66.2177%-120 - C1 -3ZXT DAPK1_HUMAN A:[7-276] -----------------ENVDDYYDT----G--EE--LGSGQFAVVKKCREKSTGLQYAAKFIKKRRT-----------REDIEREVSILKEIQ-HP-NVITLHEVYENKTDVILILELVAGGEL-FD-FLAEK--ES---LTEEEATEFLKQILNGVYYLHSLQIAHFDLKPENIML--L--DR-VPKPRIKIIDFGLAHKI-D---------------EFVAPEIV------N-YEPLGLEADMWSIGVITYILLSGASPFL---GDTKQE-TLANVSAVNYEFEDEYFSNTSALAKDFIRRLLVKDPKKRMTIQDSLQHPWIK-----------------------------------------------------------------------------------------------
129 HHSearch 64.5448%-111 * C1 *2X4F MYLK4_HUMAN A:[81-350] --------------K-QGAVNSFYTV----S--KTEILG-----QVHKCEETATGLKLAAKIIKTRGMK-------D--KEEVKNEISVMNQLD-HA-NLIQLYDAFESKNDIVLVMEYVDGGEL-FD-RIIDES-YN---LTELDTILFMKQICEGIRHMHQMYILHLDLKPENILC--V--NRDA--KQIKIIDFGLARRY-K-PR-EK-LKVNFGTPEFLAPEVV------N-YDFVSFPTDMWSVGVIAYMLLSGLSPFL---GDNDAE-TLNNILACRWDLEDEEFQDISEEAKEFISKLLIKEKSWRISASEALKHPWLSDHKLHS----RL-SAQ-------------------------------------------------------------------------------
105 PsiBlast_CBE 62.6037%-116 - C1 -2Y7J PHKG2_HUMAN D:[96-363] -----------------------YDP----K--DV--IGRGVSSVVRRCVHRATGHEFAVKIMEV---RLSPEQL-EEVREATRRETHILRQVA-GHPHIITLIDSYESSSFMFLVFDLMRKGEL-FD-YLTEK--VA---LSEKETRSIMRSLLEAVSFLHANNIVHRDLKPENI-L--L--DDNM---QIRLSDFGFSCHL-E-PG-EK-LRELCGTPGYLAPEILKCSMDET-HPGYGKEVDLWACGVILFTLLAGSPPFW---HRRQIL-MLRMIMEGQYQFSSPEWDDRSSTVKDLISRLLQVDPEARLTAEQALQHPFFER----------------------------------------------------------------------------------------------
46 PsiBlast_CBE 62.0046%-111 - C1 -2X4F MYLK4_HUMAN A:[81-347] --------------K-QGAVNSFYTV----SKTEI--LG-----QVHKCEETATGLKLAAKIIKTRGMK-------D--KEEVKNEISVMNQLD-HA-NLIQLYDAFESKNDIVLVMEYVDGGEL-FDRIIDES--YN---LTELDTILFMKQICEGIRHMHQMYILHLDLKPENILC--V--NRDAK--QIKIIDFGLARRY-K-PR-EK-LKVNFGTPEFLAPEVV------N-YDFVSFPTDMWSVGVIAYMLLSGLSPFL---GDNDAE-TLNNILACRWDLEDEEFQDISEEAKEFISKLLIKEKSWRISASEALKHPWLSDHKLHS----RL-SAQ-------------------------------------------------------------------------------
45 PsiBlast_CBE 60.8146%-114 - C1 -2X4F MYLK4_HUMAN B:[81-347] --------------K-QGAVNSFYTV----SKTEI--LGGG--GQVHKCEETATGLKLAAKIIKTRGMK-------D--KEEVKNEISVMNQLD-HA-NLIQLYDAFESKNDIVLVMEYVDGGEL-FDRIIDES--YN---LTELDTILFMKQICEGIRHMHQMYILHLDLKPENILC--V--NRDAK--QIKIIDFGLARRY-K-PR-EK-LKVNFGTPEFLAPEVV------N-YDFVSFPTDMWSVGVIAYMLLSGLSPFL---GDNDAE-TLNNILACRWDLEDEEFQDISEEAKEFISKLLIKEKSWRISASEALKHPWLSDHKLHS----RL-----------------------------------------------------------------------------------
106 PsiBlast_CBE 59.1337%-114 - C1 -2Y7J PHKG2_HUMAN C:[96-363] -----------------------YDP----K--DV--IGRGVSSVVRRCVHRATGHEFAVKIMEVTAERLSPEQL-EEVREATRRETHILRQVA-GHPHIITLIDSYESSSFMFLVFDLMRKGEL-FD-YLTEK--VA---LSEKETRSIMRSLLEAVSFLHANNIVHRDLKPENI-L--L--DDNM---QIRLSDFGFSCHL-E-PG-EK-LRELCGTPGYLAPEILKCSMDET-HPGYGKEVDLWACGVILFTLLAGSPPFW---HRRQIL-MLRMIMEGQYQFSSPEWDDRSSTVKDLISRLLQVDPEARLTAEQALQHPFFER----------------------------------------------------------------------------------------------
48 PsiBlast_CBE 58.6546%-108 - C1 -3LM0 ST17B_HUMAN A:[21-295] -----------------QSMENFNNFYILTS--KE--LGRGKFAVVRQCISKSTGQEYAAKFLKKR-----RRGQDC--RAEILHEIAVLELAK-SCPRVINLHEVYENTSEIILILEYAAGGEI-FS-LCLPELAEM---VSENDVIRLIKQILEGVYYLHQNNIVHLDLKPQNI-L--L--SSIYPLGDIKIVDFGMSRKI-------------MGTPEYLAPEIL------N-YDPITTATDMWNIGIIAYMLLTHTSPFV---GEDNQE-TYLNISQVNVDYSEETFSSVSQLATDFIQSLLVKNPEKRPTAEICLSHSWLQQWDFEN----LF-HP--------------------------------------------------------------------------------
47 PsiBlast_CBE 58.4146%-108 - C1 -3LM5 ST17B_HUMAN A:[21-295] -----------------QSMENFNNFYILTS--KE--LGRGKFAVVRQCISKSTGQEYAAKFLKKR-----RRGQDC--RAEILHEIAVLELAK-SCPRVINLHEVYENTSEIILILEYAAGGEI-FS-LCLPEL-EM---VSENDVIRLIKQILEGVYYLHQNNIVHLDLKPQNI-L--L--SSIYPLGDIKIVDFGMSRKI-------------MGTPEYLAPEIL------N-YDPITTATDMWNIGIIAYMLLTHTSPFV---GEDNQE-TYLNISQVNVDYSEETFSSVSQLATDFIQSLLVKNPEKRPTAEICLSHSWLQQWDFEN----L------------------------------------------------------------------------------------
127 HHSearch 56.6446%-107 - C1 -3LM5 ST17B_HUMAN A:[16-297] --------ENLYFQS-MENFNNFYILT---S--KE--LGRGKFAVVRQCISKSTGQEYAAKFLKKRRRG----QD-C--RAEILHEIAVLELAKSCP-RVINLHEVYENTSEIILILEYAAGGEI-FS-LCLPEL-EM---VSENDVIRLIKQILEGVYYLHQNNIVHLDLKPQNILL--S--S-IYPLGDIKIVDFGMSRKI-------------MGTPEYLAPEIL------N-YDPITTATDMWNIGIIAYMLLTHTSPFV---GEDNQE-TYLNISQVNVDYSEETFSSVSQLATDFIQSLLVKNPEKRPTAEICLSHSWLQQWDFEN----L------------------------------------------------------------------------------------
103 PsiBlast_CBE 56.3734% -92 - C1 -3C0G CSKP_HUMAN A:[23-319] --------------------EDVYEL----C--EV--IGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSP-GL-S--TEDLKREASICHMLK-HP-HIVELLETYSSDGMLYMVFEFMDGADLCFE-IVKRA--DAGFVYSEAVASHYMRQILEALRYCHDNNIIHRDVKPHCVLL--A--SKENSAP-VKLGGFGVAIQLGE-SG-LV-AGGRVGTPHFMAPEVV------K-REPYGKPVDVWGCGVILFILLSGCLPFY---G-TKER-LFEGIIKGKYKMNPRQWSHISESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYA----YK-IHL-PETV----EQLRKFNARRKLKVLAAVSFYG------------------------------------------------
100 PsiBlast_CBE 55.3134% -91 - C1 -3C0H CSKP_HUMAN B:[23-318] --------------------EDVYEL----C--EV--IGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSP-GL-S--TEDLKREASICHMLK-HP-HIVELLETYSSDGMLYMVFEFMDGADLCFE-IVKRA--DAGFVYSEAVASHYMRQILEALRYCHDNNIIHRDVKPHCVLL--A--SKENSAP-VKLGGFGVAIQLGE-SG-LV-AGGRVGTPHFMAPEVV------K-REPYGKPVDVWGCGVILFILLSGCLPFY---G-TKER-LFEGIIKGKYKMNPRQWSHISESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYA----YK-IHL-PETV----EQLRKFNARRKL----------------------------------------------------------
75 PsiBlast_CBE 54.9935% -93 - C1 -3MFS CSKP_HUMAN A:[23-319] --------------------EDVYEL----C--EV--IGKGAFSVVRRCINRETGQQFAVKIVDVAKFTSSP-GL-S--TEDLKREASICHMLK-HP-HIVELLETYSSDGMLYMVFEFMDGADLCFE-IVKRA--DAGFVYSEAVASHYMRQILEALRYCHDNNIIHRDVKPENVLL--A--SKENSAP-VKLGDFGVAIQLGE-SG-LV-AGGRVGTPHFMAPEVV------K-REPYGKPVDVWGCGVILFILLSGCLPFY---G-TKER-LFEGIIKGKYKMNPRQWSHISESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYA----YK-IHL-PETV----EQLRKFNARRKLKG--------------------------------------------------------
101 PsiBlast_CBE 54.9334% -93 - C1 -3C0H CSKP_HUMAN A:[23-318] --------------------EDVYEL----C--EV--IGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSP-GL-S--TEDLKREASICHMLK-HP-HIVELLETYSSDGMLYMVFEFMDGADLCFE-IVKRA--DAGFVYSEAVASHYMRQILEALRYCHDNNIIHRDVKPHCVLL--A--SKENSAP-VKLGGFGVAIQLGE-SG-LV-AGGRVGTPHFMAPEVV------K-REPYGKPVDVWGCGVILFILLSGCLPFY---G-TKER-LFEGIIKGKYKMNPRQWSHISESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYA----YK-IHL-PETV----EQLRKFNARRKL----------------------------------------------------------
76 PsiBlast_CBE 54.6735% -92 - C1 -3MFR CSKP_HUMAN A:[23-319] --------------------EDVYEL----C--EV--IGKGAFSVVRRCINRETGQQFAVKIVDVAKFTSSP-GL-S--TEDLKREASICHMLK-HP-HIVELLETYSSDGMLYMVFEFMDGADLCFE-IVKRA--DAGFVYSEAVASHYMRQILEALRYCHDNNIIHRDVKPENVLL--A--SKENSAP-VKLGDFGVAIQLGE-SG-LV-AGGRVGTPHFMAPEVV------K-REPYGKPVDVWGCGVILFILLSGCLPFY---G-TKER-LFEGIIKGKYKMNPRQWSHISESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYA----YK-IHL-PETV----EQLRKFNARRKLKG--------------------------------------------------------
137 HHSearch 54.2635%-107 - C1 -3Q5I ? A:[23-340] --------PGMYVRKKEGKIGESYFK----V--RK--LGS--YGEVLLCKEKNGHSEKAIKVIKK---------K-F--HEEIYNEISLLKSLD-HP-NIIKLFDVFEDKKYFYLVTEFYEGGEL-FE-QIINR--HK---FDECDAANIMKQILSGICYLHKHNIVHRDIKPENILL--E--NK-NSLLNIKIVDFGLSSFF-S-KD-YK-LRDRLGTAYYIAPEVL------K-K-KYNEKCDVWSCGVIMYILLCGYPPFG---GQNDQD-IIKKVEKGKYYFDFNDWKNISDEAKELIKLMLTYDYNKRCTAEEALNSRWIKKYANNI----NKSDQK-TLCG--ALSNMRKFEGSQKLAQAAILFIGSKL---TTLEERKELTDIFKKLDKNGDGQLDKKELIEGYNVLRNFKLGE
70 PsiBlast_CBE 53.9438%-112 - C1 -4FG7 KCC1A_HUMAN A:[12-277] --------------Q-AEDIRDIYDF----R--DV--LGTGAFSEVILAEDKRTQKLVAIKCIA-----------------SMENEIAVLHKIK-HP-NIVALDDIYESGGHLYLIMQLVSGGEL-FD-RIVEK--GF---YTERDASRLIFQVLDAVKYLHDLGIVHRDLKPENLLYYSL--DED---SKIMISDFGLSKME-D-PG----------TPGYVAPEVL------A-QK--SKAVDCWSIGVIAYILLCGYPPFY---DENDAK-LFEQILKAEYEFDSPYWDDISDSAKDFIRHLMEKDPEKRFTCEQALQHPWIA-----------------------------------------------------------------------------------------------
61 PsiBlast_CBE 53.7935% -96 - C1 -4FG8 KCC1A_HUMAN B:[14-299] -----------------EDIRDIYDF----R--DV--LGTGAFSEVILAEDKRTQKLVAIKCIAK-------------------NEIAVLHKIK-HP-NIVALDDIYESGGHLYLIMQLVSGGEL-FD-RIVEK--GF---YTERDASRLIFQVLDAVKYLHDLGIVHRDLKPENLLYYSL--DED---SKIMISDFG---------G-SV-LSTACGTPGYVAPEVL------A-QKPYSKAVDCWSIGVIAYILLCGYPPFY---DENDAK-LFEQILKAEYEFDSPYWDDISDSAKDFIRHLMEKDPEKRFTCEQALQHPWIA---GDT----AL-DKN-IHQS--VSEQIKKNFA--------------------------------------------------------------
56 PsiBlast_CBE 53.7238% -93 - C1 -2VN9 KCC2D_HUMAN A:[4-293] ---------------------DEYQL----F--EE--LGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSAR-----D--HQKLEREARICRLLK-HP-NIVRLHDSISEEGFHYLVFDLVTGGEL-FE-DIVAR--EY---YSEADASHCIQQILESVNHCHLNGIVHRDLKPENLLL--A--SKSKGAA-VKLADFGLAIEV-QGDQ-QA-WFGFAGTPGYLSPEVL------R-KDPYGKPVDMWACGVILYILLVGYPPFW---DEDQHR-LYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVA----SM-MHR-QETV--DC--LKKFNARRKLKGAILTTML-------------------------------------------------
69 PsiBlast_CBE 53.2636% -91 - C1 -3BHH KCC2B_HUMAN A:[4-293] ---------------------DEYQL----Y--ED--IG----SVVRRCVKLCTGHEYAAKIINTKKLSAR-----D--HQKLEREARICRLLK-HS-NIVRLHDSISEEGFHYLVFDLVTGGEL-FE-DIVAR--EY---YSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLL--A--SK-CKGAAVKLADFGLAIEV-QGDQ-QA-WFGFAGTPGYLSPEVL------R-KEAYGKPVDIWACGVILYILLVGYPPFW---DEDQHK-LYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVA----SM-MHR-QETV----ECLKKFNARRKLK---------------------------------------------------------
74 PsiBlast_CBE 53.0235% -88 - C1 -3MFU CSKP_HUMAN A:[23-319] --------------------EDVYEL----C--EV--IGKGAFSVVRRCINRETGQQFAVKIVDVAKFTSSP-GL-S--TEDLKREASICHMLK-HP-HIVELLETYSSDGMLYMVFEFMDGADLCFE-IVKRA--DAGFVYSEAVASHYMRQILEALRYCHDNNIIHRDVKPENVLL--A--SKENSAP-VKLGDFGVAIQLGE-SG-LV-AGGRVGTPHFMAPEVV------K-REPYGKPVDVWGCGVILFILLSGCLPFY---G-TKER-LFEGIIKGKYKMNPRQWSHISESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYA----YK-IHL-PETV----EQLRKFNARRKLKG--------------------------------------------------------
99 PsiBlast_CBE 52.8734% -88 - C1 -3C0I CSKP_HUMAN A:[23-317] --------------------EDVYEL----C--EV--IGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSP-GL-S--TEDLKREASICHMLK-HP-HIVELLETYSSDGMLYMVFEFMDGADLCFE-IVKRA--DAGFVYSEAVASHYMRQILEALRYCHDNNIIHRDVKPHCVLL--A--SKENSAP-VKLGGFGVAIQLGE-SG-LV-AGGRVGTPHFMAPEVV------K-REPYGKPVDVWGCGVILFILLSGCLPFY---G-TKER-LFEGIIKGKYKMNPRQWSHISESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYA----YK-IHL-PETV----EQLRKFNARRK-----------------------------------------------------------
55 PsiBlast_CBE 52.5038% -92 - C1 -2VN9 KCC2D_HUMAN B:[4-293] ---------------------DEYQL----F--EE--LGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSAR-----D--HQKLEREARICRLLK-HP-NIVRLHDSISEEGFHYLVFDLVTGGEL-FE-DIVAR--EY---YSEADASHCIQQILESVNHCHLNGIVHRDLKPENLLL--A--SKSKGAA-VKLADFGLAIEV-QGDQ-QA-WFGFAGTPGYLSPEVL------R-KDPYGKPVDMWACGVILYILLVGYPPFW---DEDQHR-LYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVA----SM-MHR-QETV--DC--LKKFNARRKLKGAILTTML-------------------------------------------------
53 PsiBlast_CBE 52.1837%-102 - C1 -2WEL KCC2D_HUMAN A:[4-308] ---------------------DEYQL----F--EE--LGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSAR-----D--HQKLEREARICRLLK-HP-NIVRLHDSISEEGFHYLVFDLVTGGEL-FE-DIVAR--EY---YSEADASHCIQQILESVNHCHLNGIVHRDLKPENLLL--A--SKSKGAA-VKLADFGLAIEV-QGDQ-QA-WFGFAGTPGYLSPEVL------R-KDPYGKPVDMWACGVILYILLVGYPPFW---DEDQHR-LYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRITASEALKHPWICQR--------SM-MHR-QETV--DC--LKKFNARRKLKGAILTTMLATRNFSA------------------------------------------
62 PsiBlast_CBE 52.0435% -96 - C1 -4FG8 KCC1A_HUMAN A:[12-299] --------------Q-AEDIRDIYDF----R--DV--LGTGAFSEVILAEDKRTQKLVAIKCIAK-E-----------------NEIAVLHKIK-HP-NIVALDDIYESGGHLYLIMQLVSGGEL-FD-RIVEK--GF---YTERDASRLIFQVLDAVKYLHDLGIVHRDLKPENLLYYSL--DED---SKIMISDF---------------------TPGYVAPEVL------A-QKPYSKAVDCWSIGVIAYILLCGYPPFY---DENDAK-LFEQILKAEYEFDSPYWDDISDSAKDFIRHLMEKDPEKRFTCEQALQHPWIA---GDT----AL-DKN-IHQS--VSEQIKKNFA--------------------------------------------------------------
65 PsiBlast_CBE 50.1637% -86 - C1 -2V7O KCC2G_HUMAN A:[31-320] ---------------------DDYQL----F--EE--LGKG-FSVVRRCVKKTPTQEYAAKIINTKKLSAR-----D--HQKLEREARICRLLK-HP-NIVRLHDSISEEGFHYLVFDLVTGGEL-FE-DIVAR--EY---YSEADASHCIHQILESVNHIHQHDIVHRDLKPENLLL--A--SK-CKGAAVKLADFGLAIEV-Q-GE-QQAWFGFAGTPGYLSPEVL------R-KDPYGKPVDIWACGVILYILLVGYPPFW---DEDQHK-LYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVA----SM-MHR-QETV----ECLRKFNARRKLKG--------------------------------------------------------
54 PsiBlast_CBE 49.6341%-118 - C1 -2W4O KCC4_HUMAN A:[51-310] -------------------LSDFFEV----E--SE--LGRGATSIVYRCKQKGTQKPYALKVLKK---------------------IGVLLRLS-HP-NIIKLKEIFETPTEISLVLELVTGGEL-FD-RIVEK--GY---YSERDAADAVKQILEAVAYLHENGIVHRDLKPEN-LL--Y--ATPAPDAPLKIADF--------------------GTPGYCAPEIL------R-GCAYGPEVDMWSVGIITYILLCGFEPFYDERGD--QF-MFRRILNCEYYFISPWWDEVSLNAKDLVRKLIVLDPKKRLTTFQALQHPWVTGKAANF----VH-MDT-AQKK--LQEFNARRKLKAAVKAVVASS---------------------------------------------------
58 PsiBlast_CBE 49.2835% -92 - C1 -4FG9 KCC1A_HUMAN A:[12-314] --------------Q-AEDIRDIYDF----R