@TOME V2.3
(Nov 2016)

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Alignment:

3D Common Core:

Structural Clustering:

Modeller Result :

Complexes Modeling
Templates Information:
Sequence & Result Tab:

Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : DCLK2_HUMAN: (2015-10-06 )
MASTRSIELEHFEERDKRPRPGSRRGAPSSSGGSSSSGPKGNGLIPSPAHSAHCSFYRTRTLQALSSEKKAKKARFYRNGDRYFKGLVFAISSDRFRSFDALLIELTRSLSDNVNLPQGVRTIYTIDGSRKVTSLDELLEGESYVCASNEPFRKVDYTKNINPNWSVNIKGGTSRALAAASSVKSEVKESKDFIKPKLVTVIRSGVKPRKAVRILLNKKTAHSFEQVLTDITEAIKLDSGVVKRLCTLDGKQVTCLQDFFGDDDVFIACGPEKFRYAQDDFVLDHSECRVLKSSYSRSSAVKYSGSKSPGPSRRSKSPASVNGTPSSQLSTPKSTKSSSSSPTSPGSFRGLKQISAHGRSSSNVNGGPELDRCISPEGVNGNRCSESSTLLEKYKIGKVIGDGNFAVVKECIDRSTGKEFALKIIDKAKCCGKEHLIENEVSILRRVKHPNIIMLVEEMETATELFLVMELVKGGDLFDAITSSTKYTERDGSAMVYNLANALRYLHGLSIVHRDIKPENLLVCEYPDGTKSLKLGDFGLATVVEGPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCGFPPFRSENNLQEDLFDQILAGKLEFPAPYWDNITDSAKELISQMLQVNVEARCTAGQILSHPWVSDDASQENNMQAEVTGKLKQHFNNALPKQNSTTTGVSVIMNTALDKEGQIFCSKHCQDSGRPGMEPISPVPPSVEEIPVPGEAVPAPTPPESPTPHPPPAAPGGERAGTWRRHRD

Atome Classification :

(47 SA) .........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420....--...-------430----....-..--..------.440.....-.-.450.......460.......470.......480.......490.......500.......510.......520.......530.......540.-----..---.---.---..550.......560.------.------....-.570.......580.......590.-......600.......610.......620.......630.......640.......650.......660.......670.......680.......690.......700.......710.......720.......730.......740.......750.......760....
(Atome) (Ident) (Tito) (Num) (Ligand) (Uniprot) MASTRSIELEHFEERDKRPRPGSRRGAPSSSGGSSSSGPKGNGLIPSPAHSAHCSFYRTRTLQALSSEKKAKKARFYRNGDRYFKGLVFAISSDRFRSFDALLIELTRSLSDNVNLPQGVRTIYTIDGSRKVTSLDELLEGESYVCASNEPFRKVDYTKNINPNWSVNIKGGTSRALAAASSVKSEVKESKDFIKPKLVTVIRSGVKPRKAVRILLNKKTAHSFEQVLTDITEAIKLDSGVVKRLCTLDGKQVTCLQDFFGDDDVFIACGPEKFRYAQDDFVLDHSECRVLKSSYSRSSAVKYSGSKSPGPSRRSKSPASVNGTPSSQLSTPKSTKSSSSSPTSPGSFRGLKQISAHGRSSSNVNGGPELDRCISPEGVNGNRCSESSTLLEKYKIGKVIGDGNFAVVKECIDRSTGKEFALKIID--KAK-------C------CGKE-HL--IE------NEVSILRRV-K-HPNIIMLVEEMETATELFLVMELVKGGDLFDAITSSTKYTERDGSAMVYNLANALRYLHGLSIVHRDIKPENLLVCEYPDGTKSLKLGDFGLATV-----VE---G---P---LYTVCGTPTYVAPEII------A------ETGY-GLKVDIWAAGVITYILLCGFPPFRS-ENNLQEDLFDQILAGKLEFPAPYWDNITDSAKELISQMLQVNVEARCTAGQILSHPWVSDDASQENNMQAEVTGKLKQHFNNALPKQNSTTTGVSVIMNTALDKEGQIFCSKHCQDSGRPGMEPISPVPPSVEEIPVPGEAVPAPTPPESPTPHPPPAAPGGERAGTWRRHRD
13 PsiBlast_PDB 82.1339%-118 - C1 -2WEL KCC2D_HUMAN A:[1-287] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SMTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIIN--TKK-------L------SARD-HQK-LE------REARICRLL-K-HPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGIVHRDLKPENLLLASKSKGA-AVKLADFGLAIE-----VQ---GDQQA---WFGFAGTPGYLSPEVL------R------KDPY-GKPVDMWACGVILYILLVGYPPFWD-ED--QHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRITASEALKHPWICQR----SMMHRQETVDCLKKFNARRKLKGAILTTMLATRNFSA-----------------------------------------------------------------------
10 PsiBlast_PDB 81.8940%-107 - C1 -3BHH KCC2B_HUMAN A:[1-287] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SMTDEYQLYEDIG----SVVRRCVKLCTGHEYAAKIIN--TKK-------L------SARD-HQK-LE------REARICRLL-K-HSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKCKGA-AVKLADFGLAIE-----VQ---GDQQA---WFGFAGTPGYLSPEVL------R------KEAY-GKPVDIWACGVILYILLVGYPPFWD-ED--QHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKLK--------------------------------------------------------------------------------------
25 PsiBlast_CBE 81.7740%-109 - C1 -3BHH KCC2B_HUMAN B:[2-287] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTDEYQLYEDIGK---SVVRRCVKLCTGHEYAAKIIN--TKK-------L------SARD-HQK-LE------REARICRLL-K-HSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKCKGA-AVKLADFGLAIE-----VQ---GDQQA---WFGFAGTPGYLSPEVL------R------KEAY-GKPVDIWACGVILYILLVGYPPFWD-ED--QHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKLK--------------------------------------------------------------------------------------
6 PsiBlast_PDB 81.0143%-116 - C1 -4FG7 KCC1A_HUMAN A:[9-277] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RWKQAEDIRDIYDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIA-------------------------S--ME------NEIAVLHKI-K-HPNIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLGIVHRDLKPENLLYYSLDEDSK-IMISDFGLSK------ME---D---PG--------TPGYVAPEVL------A------QK---SKAVDCWSIGVIAYILLCGYPPFYD-ENDAK--LFEQILKAEYEFDSPYWDDISDSAKDFIRHLMEKDPEKRFTCEQALQHPWIA------------------------------------------------------------------------------------------------------------------
21 PsiBlast_CBE 80.9342%-114 - C1 -4FG8 KCC1A_HUMAN B:[14-299] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EDIRDIYDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIA--K---------------------------------NEIAVLHKI-K-HPNIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLGIVHRDLKPENLLYYSLDEDSK-IMISDFG-------------------GSVLSTACGTPGYVAPEVL------A------QKPY-SKAVDCWSIGVIAYILLCGYPPFYD-ENDAK--LFEQILKAEYEFDSPYWDDISDSAKDFIRHLMEKDPEKRFTCEQALQHPWIAGDTALDKNIHQSVSEQIKKNFA--------------------------------------------------------------------------------------------
7 PsiBlast_PDB 79.3242%-102 - C1 -2JC6 KCC1D_HUMAN A:[24-314] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FEFKETLGTGAFSEVVLAEEKATGKLFAVKCIP--KKA-------------------SS--IE------NEIAVLRKI-K-HENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESK-IMIS--------------------------------PGYVAPEVL------A------QKPY-SKAVDCWSIGVIAYILLCGYPPFYD-ENDSK--LFEQILKAEYEFDSPYWDDISDSAKDFIRNLMEKDPNKRYTCEQAARHPWIAGDTALNKNIHESVSAQIRKNFAKSKWRQAFNAT---------------------------------------------------------------------------------
3 PsiBlast_PDB 78.7342%-108 - C1 -4FG8 KCC1A_HUMAN A:[10-299] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WKQAEDIRDIYDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIA--KE--------------------------------NEIAVLHKI-K-HPNIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLGIVHRDLKPENLLYYSLDEDSK-IMISDF-----------------------------TPGYVAPEVL------A------QKPY-SKAVDCWSIGVIAYILLCGYPPFYD-ENDAK--LFEQILKAEYEFDSPYWDDISDSAKDFIRHLMEKDPEKRFTCEQALQHPWIAGDTALDKNIHQSVSEQIKKNFA--------------------------------------------------------------------------------------------
34 PsiBlast_CBE 78.1240%-117 - C1 -2Y7J PHKG2_HUMAN C:[94-362] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QKYDPKDVIGRGVSSVVRRCVHRATGHEFAVKIMEV-TAE-------R------LSPE-QL--EEVREATRRETHILRQV-AGHPHIITLIDSYESSSFMFLVFDLMRKGELFDYLTEKVALSEKETRSIMRSLLEAVSFLHANNIVHRDLKPENILL----DDNMQIRLSDFGFSCH-----LEPG-E---K---LRELCGTPGYLAPEILKCSMDET------HPGY-GKEVDLWACGVILFTLLAGSPPFWH-RRQIL--MLRMIMEGQYQFSSPEWDDRSSTVKDLISRLLQVDPEARLTAEQALQHPFFER-----------------------------------------------------------------------------------------------------------------
22 PsiBlast_CBE 78.0642%-101 - C1 -4FG9 KCC1A_HUMAN B:[14-312] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EDIRDIYDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIA--K----------------------------------EIAVLHKI-K-HPNIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLGIVHRDLKPENLLYYSLDEDSK-IMISDF--------------------V--LSTACGTPGYVAPEVL------A------QKPY-SKAVDCWSIGVIAYILLCGYPPFYD-ENDAK--LFEQILKAEYEFDSPYWDDISDSAKDFIRHLMEKDPEKRFTCEQALQHPWIAGDTALDKNIHQSVSEQIKKNFAKSKWKQAFNATAVVR-----------------------------------------------------------------------------
9 PsiBlast_PDB 77.9737% -94 - C1 -2V7O KCC2G_HUMAN A:[15-321] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TENLYFQSMATCTRFTDDYQLFEELGKG-FSVVRRCVKKTPTQEYAAKIIN--TKK-------L------SARD-HQK-LE------REARICRLL-K-HPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHDIVHRDLKPENLLLASKCKGA-AVKLADFGLAIE-----VQ---GEQQA---WFGFAGTPGYLSPEVL------R------KDPY-GKPVDIWACGVILYILLVGYPPFWD-ED--QHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKLKG-------------------------------------------------------------------------------------
23 PsiBlast_CBE 77.7042%-103 - C1 -2JC6 KCC1D_HUMAN C:[24-314] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FEFKETLGTGAFSEVVLAEEKATGKLFAVKCIP--KKA--------------------S--IE------NEIAVLRKI-K-HENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESK-IMIS--------------------------------PGYVAPEVL------A------QKPY-SKAVDCWSIGVIAYILLCGYPPFYD-ENDSK--LFEQILKAEYEFDSPYWDDISDSAKDFIRNLMEKDPNKRYTCEQAARHPWIAGDTALNKNIHESVSAQIRKNFAKSKWRQAFNAT---------------------------------------------------------------------------------
65 PsiBlast_CBE 77.4038%-108 - C1 -2W4K DAPK1_HUMAN A:[13-282] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YDTGEELGSGQFAVVKKCREKSTGLQYAAKFIK--KRR-------TKSSRRGVSRE-D---IE------REVSILKEI-Q-HPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQILNGVYYLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHK-----IDFG-N---E---FKNIFGTPEFVAPEIV------N------YEPL-GLEADMWSIGVITYILLSGASPFLG-DTK-QETLAN-VSAVNYEFEDEYFSNTSALAKDFIRRLLVKDPKKRMTIQDSLQHPWIKPKDTQQALSRKASAVNMEKFKKFAAR----------------------------------------------------------------------------------------
33 PsiBlast_CBE 77.3540%-117 - C1 -2Y7J PHKG2_HUMAN D:[94-362] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QKYDPKDVIGRGVSSVVRRCVHRATGHEFAVKIMEV-----------R------LSPE-QL--EEVREATRRETHILRQV-AGHPHIITLIDSYESSSFMFLVFDLMRKGELFDYLTEKVALSEKETRSIMRSLLEAVSFLHANNIVHRDLKPENILL----DDNMQIRLSDFGFSCH-----LEPG-E---K---LRELCGTPGYLAPEILKCSMDET------HPGY-GKEVDLWACGVILFTLLAGSPPFWH-RRQIL--MLRMIMEGQYQFSSPEWDDRSSTVKDLISRLLQVDPEARLTAEQALQHPFFER-----------------------------------------------------------------------------------------------------------------
35 PsiBlast_CBE 77.2640%-117 - C1 -2Y7J PHKG2_HUMAN A:[94-362] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QKYDPKDVIGRGVSSVVRRCVHRATGHEFAVKIMEV-TAE-------R------LSPE-QL--EEVREATRRETHILRQV-AGHPHIITLIDSYESSSFMFLVFDLMRKGELFDYLTEKVALSEKETRSIMRSLLEAVSFLHANNIVHRDLKPENILL----DDNMQIRLSDFGFSCH-----LEPG-E---K---LRELCGTPGYLAPEILKCSMDET------HPGY-GKEVDLWACGVILFTLLAGSPPFWH-RRQIL--MLRMIMEGQYQFSSPEWDDRSSTVKDLISRLLQVDPEARLTAEQALQHPFFER-----------------------------------------------------------------------------------------------------------------
27 PsiBlast_CBE 77.2239%-102 - C1 -2VN9 KCC2D_HUMAN B:[1-287] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SMTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIIN--TKK-------L------SARD-HQK-LE------REARICRLL-K-HPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGIVHRDLKPENLLLASKSKGA-AVKLADFGLAIE-----VQ---GDQQA---WFGFAGTPGYLSPEVL------R------KDPY-GKPVDMWACGVILYILLVGYPPFWD-ED--QHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKLKGAILTTML------------------------------------------------------------------------------
53 PsiBlast_CBE 77.1338%-114 - C1 -1QL6 PHKG1_RABIT A:[15-291] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FYENYEPKEILGRGVSSVVRRCIHKPTCKEYAVKIIDVTGGG-------S------FSAE-EV--QELREATLKEVDILRKV-SGHPNIIQLKDTYETNTFFFLVFDLMKKGELFDYLTEKVTLSEKETRKIMRALLEVICALHKLNIVHRDLKPENILL----DDDMNIKLTDFGFSCQ-----LDPG-E---K---LRSVCGTPSYLAPEII------ECSMNDNHPGY-GKEVDMWSTGVIMYTLLAGSPPFWH-RKQML--MLRMIMSGNYQFGSPEWDDYSDTVKDLVSRFLVVQPQKRYTAEEALAHPFFQQYV---------------------------------------------------------------------------------------------------------------
77 PsiBlast_CBE 76.8639%-118 - C1 -2PHK PHKG1_RABIT A:[2-273] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FYENYEPKEILGRGVSSVVRRCIHKPTCKEYAVKIIDVTGGG-------S------FSAE-EV--QELREATLKEVDILRKV-SGHPNIIQLKDTYETNTFFFLVFDLMKKGELFDYLTEKVTLSEKETRKIMRALLEVICALHKLNIVHRDLKPENILL----DDDMNIKLTDFGFSCQ-----LDPG-E---K---LREVCGTPSYLAPEII------ECSMNDNHPGY-GKEVDMWSTGVIMYTLLAGSPPFWH-RKQML--MLRMIMSGNYQFGSPEWDDYSDTVKDLVSRFLVVQPQKRYTAEEALAHPFFQQY----------------------------------------------------------------------------------------------------------------
67 PsiBlast_CBE 76.6736%-109 - C1 -2Y0A DAPK1_HUMAN A:[13-282] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YDTGEELGSGQFAVVKKCREKSTGLQYAAKFIK--KRR-------TKSSRRGVSRE-D---IE------REVSILKEI-Q-HPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQILNGVYYLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHK-----IDFG-N---E---FKNIFGTPEFVAPEIV------N------YEPL-GLEADMWSIGVITYILLSGASPFLG-DT--KQETLANVSAVNYEFEDEYFSNTSALAKDFIRRLLVKDPKKRMTIQDSLQHPWIKPKDTQQALSRKASAVNMEKFKKFAAR----------------------------------------------------------------------------------------
14 PsiBlast_PDB 76.6439%-103 - C1 -2VN9 KCC2D_HUMAN A:[1-287] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SMTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIIN--TKK-------L------SARD-HQK-LE------REARICRLL-K-HPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGIVHRDLKPENLLLASKSKGA-AVKLADFGLAIE-----VQ---GDQQA---WFGFAGTPGYLSPEVL------R------KDPY-GKPVDMWACGVILYILLVGYPPFWD-ED--QHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKLKGAILTTML------------------------------------------------------------------------------
60 PsiBlast_CBE 76.6338%-117 - C1 -1PHK PHKG1_RABIT A:[15-291] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FYENYEPKEILGRGVSSVVRRCIHKPTCKEYAVKIIDVTGGG-------S------FSAE-EV--QELREATLKEVDILRKV-SGHPNIIQLKDTYETNTFFFLVFDLMKKGELFDYLTEKVTLSEKETRKIMRALLEVICALHKLNIVHRDLKPENILL----DDDMNIKLTDFGFSCQ-----LDPG-E---K---LREVCGTPSYLAPEII------ECSMNDNHPGY-GKEVDMWSTGVIMYTLLAGSPPFWH-RKQML--MLRMIMSGNYQFGSPEWDDYSDTVKDLVSRFLVVQPQKRYTAEEALAHPFFQQYV---------------------------------------------------------------------------------------------------------------
8 PsiBlast_PDB 76.5638%-100 - C1 -2JAM KCC1G_HUMAN A:[6-290] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NIRKTFIFMEVLGSGAFSEVFLVKQRLTGKLFALKCIK--KS---------------------S--LE------NEIAVLKKI-K-HENIVTLEDIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVKYLHENGIVHRDLKPENLLYLT-PEENSKIMITDFGLSKM-----EQN--G---I---MSTACGTPGYVAPEVL------A------QKPY-SKAVDCWSIGVITYILLCGYPPFYE-ET--ESKLFEKIKEGYYEFESPFWDDISESAKDFICHLLEKDPNERYTCEKALSHPWIDGNTALHRDIYPSVSLQIQKNFAKS------------------------------------------------------------------------------------------
4 PsiBlast_PDB 76.3942% -97 - C1 -4FG9 KCC1A_HUMAN A:[10-312] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WKQAEDIRDIYDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIA--KE-------------------------E------NEIAVLHKI-K-HPNIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLGIVHRDLKPENLLYYSLDEDSK-IMISDF------------------------------PGYVAPEVL------A------QKPY-SKAVDCWSIGVIAYILLCGYPPFYD-ENDAK--LFEQILKAEYEFDSPYWDDISDSAKDFIRHLMEKDPEKRFTCEQALQHPWIAGDTALDKNIHQSVSEQIKKNFAKSKWKQAFNATAVVR-----------------------------------------------------------------------------
74 PsiBlast_CBE 75.8338%-109 - C1 -2YAK DAPK1_HUMAN A:[13-278] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YDTGEELGSGQFAVVKKCREKSTGLQYAAKFIK--KRR-------TKSSRRGVSRE-D---IE------REVSILKEI-Q-HPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQILNGVYYLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHK-----IDFG-N---E---FKNIFGTPEFVAPEIV------N------YEPL-GLEADMWSIGVITYILLSGASPFLG-DTK-QETLAN-VSAVNYEFEDEYFSNTSALAKDFIRRLLVKDPKKRMTIQDSLQHPWIKPK----------------------------------------------------------------------------------------------------------------
49 PsiBlast_CBE 75.6137%-106 - C1 -2YAA DAPK2_MOUSE B:[14-289] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YDIGEELGSGQFAIVKKCREKSTGLEYAAKFIK--KRQSRASRRGV------CREE-----IE------REVSILRQV-L-HPNIITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEEATSFIKQILDGVNYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHE-----IE---DGV-E---FKNIFGTPEFVAPEIV------N------YEPL-GLEADMWSIGVITYILLSGASPFLG-DTK-QETLAN-ITAVSYDFDEEFFSQTSELAKDFIRKLLVKETRKRLTIQEALRHPWITPVDTQQAMVRRESVVNLENFKKQYV-----------------------------------------------------------------------------------------
61 PsiBlast_CBE 75.5638%-107 - C1 -4B4L DAPK1_HUMAN A:[15-284] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YDTGEELGSGQFAVVKKCREKSTGLQYAAKFIK--KRR-------TKSSRRGVSRE-D---IE------REVSILKEI-Q-HPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQILNGVYYLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHK-----IDFG-N---E---FKNIFGTPEFVAPEIV------N------YEPL-GLEADMWSIGVITYILLSGASPFLG-DTK-QETLAN-VSAVNYEFEDEYFSNTSALAKDFIRRLLVKDPKKRMTIQDSLQHPWIKPKDTQQALSRKASAVNMEKFKKFAAAK---------------------------------------------------------------------------------------
50 PsiBlast_CBE 75.4637%-108 - C1 -2YAA DAPK2_MOUSE A:[14-289] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YDIGEELGSGQFAIVKKCREKSTGLEYAAKFIK--KRQSRASRRGV------CREE-----IE------REVSILRQV-L-HPNIITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEEATSFIKQILDGVNYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHE-----IE---DGV-E---FKNIFGTPEFVAPEIV------N------YEPL-GLEADMWSIGVITYILLSGASPFLG-DTK-QETLAN-ITAVSYDFDEEFFSQTSELAKDFIRKLLVKETRKRLTIQEALRHPWITPVDTQQAMVRRESVVNLENFKKQYV-----------------------------------------------------------------------------------------
75 PsiBlast_CBE 75.3236%-110 - C1 -4TXC DAPK1_HUMAN A:[32-296] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YDTGEELGSGQFAVVKKCREKSTGLQYAAKFIK--KRR-------TKSSRRGVSRE-D---IE------REVSILKEI-Q-HPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQILNGVYYLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHK-----IDFG-N---E---FKNIFGTPEFVAPEIV------N------YEPL-GLEADMWSIGVITYILLSGASPFLG-DT--KQETLANVSAVNYEFEDEYFSNTSALAKDFIRRLLVKDPKKRMTIQDSLQHPWIKP-----------------------------------------------------------------------------------------------------------------
78 PsiBlast_CBE 75.0737%-110 - C1 -1WVY DAPK1_HUMAN A:[13-275] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YDTGEELGSGQFAVVKKCREKSTGLQYAAKFIK--KRR-------TKSSRRGVSRE-D---IE------REVSILKEI-Q-HPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQILNGVYYLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHK-----IDFG-N---E---FKNIFGTPEFVAPEIV------N------YEPL-GLEADMWSIGVITYILLSGASPFLG-DT--KQETLANVSAVNYEFEDEYFSNTSALAKDFIRRLLVKDPKKRMTIQDSLQHPWIK------------------------------------------------------------------------------------------------------------------
70 PsiBlast_CBE 74.9838%-118 - C1 -3ZXT DAPK1_HUMAN D:[13-276] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YDTGEELGSGQFAVVKKCREKSTGLQYAAKFI--------------------VSRE-D---IE------REVSILKEI-Q-HPNVITLHEVYENKTDVILILELVAGGELFDFLAE----TEEEATEFLKQILNGVYYLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHK-----ID-----------------TPEFVAPEIV------N------YEPL-GLEADMWSIGVITYILLSGASPFLG-DTK-QETLAN-VSAVNYEFEDEYFSNTSALAKDFIRRLLVKDPKKRMTIQDSLQHPWIK------------------------------------------------------------------------------------------------------------------
15 PsiBlast_PDB 74.8037% -97 - C1 -2W4O KCC4_HUMAN A:[43-330] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IDG---SNRDALSDFFEVESELGRGATSIVYRCKQKGTQKPYALKVLK--K-----------------------------------IGVLLRL-S-HPNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQILEAVAYLHENGIVHRDLKPENLLYAT-PAPDAPLKIADF----------------------------GTPGYCAPEIL------R------GCAY-GPEVDMWSVGIITYILLCGFEPFYD-ERG-DQFMFRRILNCEYYFISPWWDEVSLNAKDLVRKLIVLDPKKRLTTFQALQHPWVTGKAA--NFVHMDTAQKKLQEFNARRKLKAAVKAVVASS----------------------------------------------------------------------------
24 PsiBlast_CBE 74.7838% -99 - C1 -2JAM KCC1G_HUMAN B:[4-289] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TTNIRKTFIFMEVLGSGAFSEVFLVKQRLTGKLFALKCIK--KS---------------------S--LE------NEIAVLKKI-K-HENIVTLEDIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVKYLHENGIVHRDLKPENLLYLT-PEENSKIMITDFGLSKM-----EQN--G---I---MSTACGTPGYVAPEVL------A------QKPY-SKAVDCWSIGVITYILLCGYPPFYE-ET--ESKLFEKIKEGYYEFESPFWDDISESAKDFICHLLEKDPNERYTCEKALSHPWIDGNTALHRDIYPSVSLQIQKNFAK-------------------------------------------------------------------------------------------
80 PsiBlast_CBE 74.5437%-110 - C1 -2W4J DAPK1_HUMAN A:[13-275] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YDTGEELGSGQFAVVKKCREKSTGLQYAAKFIK--KRR-------TKSSRRGVSRE-D---IE------REVSILKEI-Q-HPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQILNGVYYLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHK-----IDFG-N---E---FKNIFGTPEFVAPEIV------N------YEPL-GLEADMWSIGVITYILLSGASPFLG-DT--KQETLANVSAVNYEFEDEYFSNTSALAKDFIRRLLVKDPKKRMTIQDSLQHPWIKP-----------------------------------------------------------------------------------------------------------------
76 PsiBlast_CBE 74.4538%-109 - C1 -4UV0 ? A:[15-284] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YDTGEELGSGQFAVVKKCREKSTGLQYAAKFIK--KRR-------TKSSRRGVSRE-D---IE------REVSILKEI-Q-HPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQILNGVYYLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHK-----IDFG-N---E---FKNIFGTPEFVAPEIV------N------YEPL-GLEADMWSIGVITYILLSGASPFLG-DTK-QETLAN-VSAVNYEFEDEYFSNTSALAKDFIRRLLVKDPKKRMTIQDSLQHPWIKPKDTQQALSRKACAVNMEKFKKFAAR----------------------------------------------------------------------------------------
62 PsiBlast_CBE 72.8338%-108 - C1 -2XUU DAPK1_HUMAN A:[13-282] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YDTGEELGSGQFAVVKKCREKSTGLQYAAKFIK--KRR-------TKSSRRGVSRE-D---IE------REVSILKEI-Q-HPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQILNGVYYLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHK-----IDFG-N---E---FKNIFGTPAFVAPEIV------N------YEPL-GLEADMWSIGVITYILLSGASPFLG-DTK-QETLAN-VSAVNYEFEDEYFSNTSALAKDFIRRLLVKDPKKRMTIQDSLQHPWIKPKDTQQALSRKASAVNMEKFKKFAAR----------------------------------------------------------------------------------------
42 PsiBlast_CBE 72.7438%-109 - C1 -4CZT CIPKN_ARATH A:[8-267] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TRVGKYELGRTLGEGTFAKVKFARNVENGDNVAIKVID--KEK-------V------LKNK-MIAQIK------REISTMKLI-K-HPNVIRMFEVMASKTKIYFVLEFVTGGELFDKISSNGRLKEDEARKYFQQLINAVDYCHSRGVYHRDLKPENLLL----DANGALKVSDFGLSALPQQVRED---G---L---LHTTCGTPNYVAPEVI------N------NKGYDGAKADLWSCGVILFVLMAGYLPFED-SN--LTSLYKKIF--KAEFTCPPW--FSASAKKLIKRILDPNPATRITFAEVIENEWFKKGYKAPKFENVSLDDVDAIFDDSGES----------------------------------------------------------------------------------------
46 PsiBlast_CBE 72.2238%-112 - C1 -4CZU CIPKN_ARATH A:[8-267] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TRVGKYELGRTLGEGTFAKVKFARNVENGDNVAIKVID--KEK-------V------LKNK-MIAQIK------REISTMKLI-K-HPNVIRMFEVMASKTKIYFVLEFVTGGELFDKISSNGRLKEDEARKYFQQLINAVDYCHSRGVYHRDLKPENLLL----DANGALKVSDFGLSALPQQVRED---G---L---LHDTCGTPNYVAPEVI------N------NKGYDGAKADLWSCGVILFVLMAGYLPFED-SN--LTSLYKKIF--KAEFTCPPW--FSASAKKLIKRILDPNPATRITFAEVIENEWFKKGYKAPKFENDDVDAIFDDSGESKNLVV--------------------------------------------------------------------------------------
40 PsiBlast_CBE 72.1338%-112 - C1 -4CZT CIPKN_ARATH C:[10-267] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VGKYELGRTLGEGTFAKVKFARNVENGDNVAIKVID--KEK-------V------LKNK-MIAQIK------REISTMKLI-K-HPNVIRMFEVMASKTKIYFVLEFVTGGELFDKISSNGRLKEDEARKYFQQLINAVDYCHSRGVYHRDLKPENLLL----DANGALKVSDFGLSALPQQVRED---G---L---LHTTCGTPNYVAPEVI------N------NKGYDGAKADLWSCGVILFVLMAGYLPFED-SN--LTSLYKKIF--KAEFTCPPW--FSASAKKLIKRILDPNPATRITFAEVIENEWFKKGYKAPKFENADVSLDDVDAIFDDSG----------------------------------------------------------------------------------------
41 PsiBlast_CBE 72.1038%-108 - C1 -4CZT CIPKN_ARATH B:[8-267] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TRVGKYELGRTLGEGTFAKVKFARNVENGDNVAIKVID--KEK-------V------LKNK-MIAQIK------REISTMKLI-K-HPNVIRMFEVMASKTKIYFVLEFVTGGELFDKISSNGRLKEDEARKYFQQLINAVDYCHSRGVYHRDLKPENLLL----DANGALKVSDFGLSALPQQVRED---G---L---LHTTCGTPNYVAPEVI------N------NKGYDGAKADLWSCGVILFVLMAGYLPFED-SN--LTSLYKKIF--KAEFTCPPW--FSASAKKLIKRILDPNPATRITFAEVIENEWFKKGYKAPKFEDDVDAIFDDSG----------------------------------------------------------------------------------------------
44 PsiBlast_CBE 71.7438%-112 - C1 -4CZU CIPKN_ARATH C:[9-267] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RVGKYELGRTLGEGTFAKVKFARNVENGDNVAIKVID--KEK-------V------LKNK-MIAQIK------REISTMKLI-K-HPNVIRMFEVMASKTKIYFVLEFVTGGELFDKISSNGRLKEDEARKYFQQLINAVDYCHSRGVYHRDLKPENLLL----DANGALKVSDFGLSALPQQVRED---G---L---LHDTCGTPNYVAPEVI------N------NKGYDGAKADLWSCGVILFVLMAGYLPFED-SN--LTSLYKKIF--KAEFTCPPW--FSASAKKLIKRILDPNPATRITFAEVIENEWFKKGYKAPKFENADVDAIFDDS----------------------------------------------------------------------------------------------
19 PsiBlast_PDB 71.5639%-104 - C1 -2WEI ? A:[19-286] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TFAERYNIVCMLGKGSFGEVLKCKDRITQQEYAVKVIN--KAS-------A------KNKDTST--IL------REVELLKKL-D-HPNIMKLFEILEDSSSFYIVGELYTGGELFDEIIKRKRFSEHDAARIIKQVFSGITYMHKHNIVHRDLKPENILL-ESKEKDCDIKIIDFGLSTC-----FQ---QNT-K---MKDRIGTAYYIAPEVL------R------GT-Y-DEKCDVWSAGVILYILLSGTPPFYG-KN--EYDILKRVETGKYAFDLPQWRTISDDAKDLIRKMLTFHPSLRITATQCLEHPWIQKYSSE-------------------------------------------------------------------------------------------------------------
45 PsiBlast_CBE 71.3938%-108 - C1 -4CZU CIPKN_ARATH B:[8-267] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TRVGKYELGRTLGEGTFAKVKFARNVENGDNVAIKVID--KEK-------V------LKNK-MIAQIK------REISTMKLI-K-HPNVIRMFEVMASKTKIYFVLEFVTGGELFDKISSNGRLKEDEARKYFQQLINAVDYCHSRGVYHRDLKPENLLL----DANGALKVSDFGLSALPQQVRED---G---L---LHDTCGTPNYVAPEVI------N------NKGYDGAKADLWSCGVILFVLMAGYLPFED-SN--LTSLYKKIF--KAEFTCPPW--FSASAKKLIKRILD