@TOME V2.3
(Nov 2016)

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Alignment:

3D Common Core:

Structural Clustering:

Modeller Result :

Complexes Modeling
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Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : DMPK_HUMAN: (2015-10-06 )
MSAEVRLRRLQQLVLDPGFLGLEPLLDLLLGVHQELGASELAQDKYVADFLQWAEPIVVRLKEVRLQRDDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLVNGDRRWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAEMARFYLAEIVMAIDSVHRLGYVHRDIKPDNILLDRCGHIRLADFGSCLKLRADGTVRSLVAVGTPDYLSPEILQAVGGGPGTGSYGPECDWWALGVFAYEMFYGQTPFYADSTAETYGKIVHYKEHLSLPLVDEGVPEEARDFIQRLLCPPETRLGRGGAGDFRTHPFFFGLDWDGLRDSVPPFTPDFEGATDTCNFDLVEDGLTAMVSGGGETLSDIREGAPLGVHLPFVGYSYSCMALRDSEVPGPTPMELEAEQLLEPHVQAPSLEPSVSPQDETAEVAVPAAVPAAEAEAEVTLRELQEALEEEVLTRQSLSREMEAIRTDNQNFASQLREAEARNRDLEAHVRQLQERMELLQAEGATAVTGVPSPRATDPPSHLDGPPAVAVGQCPLVGPGPMHRRHLLLPARVPRPGLSEALSLLLFAVVLSRAAALGCIGLVAHAGQLTAVWRRPGAARAP

Atome Classification :

(53 SA) .........10.....------..-----.-20........30........40........50.-.......60........70........80........90--.---.---..----.....100.......110........120..-.-.-...130.......140.......150.......160---.......170........180......-.190.......200.......210.......220.......230.......240.......250.......260.......270.......280.---......290--.........300........310.......-320..-...--.---.--.330----.......340-......--.--.--350.......360.......370.......380.......390.......400...---....410..---.....420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570.......580.......590.......600.......610.......620.......
(Atome) (Ident) (Tito) (Num) (Ligand) (Uniprot) MSAEVRLRRLQQLVLD------PG-----F-LGLEPLLDLLLGVHQELGASELAQDKYVADFLQ-WAEPIVVRLKEVRLQRDDFEILKVIGRGAFSEVAVVKM---K---Q---TG----QVYAMKIMNKWDMLKR-GEVSCFREERDVLV-N-G-DRRWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSK---FGERIPAE-MARFYLAEIVMAIDSVHR-LGYVHRDIKPDNILLDRCGHIRLADFGSCLKLRADGTVRSLVAVGTPDYLSPEILQAVGGGPGTGSYGPECDWWALGVFAYEMFYGQTPFYADST---AETYGKI----VHYKEHLSLPL-VDEGVPEEARDFIQRLLC-P-PET-RLG--R---G--GAGD----FRTHPFFFG--LDWDGL--R--D--SVPPFTPDFEGATDTCNFDLVEDGLTAMVSGGGETLSDIREGAPLGVHLPFVGYSY---SCMALRDSE---VPGPTPMELEAEQLLEPHVQAPSLEPSVSPQDETAEVAVPAAVPAAEAEAEVTLRELQEALEEEVLTRQSLSREMEAIRTDNQNFASQLREAEARNRDLEAHVRQLQERMELLQAEGATAVTGVPSPRATDPPSHLDGPPAVAVGQCPLVGPGPMHRRHLLLPARVPRPGLSEALSLLLFAVVLSRAAALGCIGLVAHAGQLTAVWRRPGAARAP
5 PsiBlast_PDB 80.6159%-124 - C2 -4UAK MRCKB_HUMAN A:[4-416] -SAKVRLKKLEQLLLDGPWRN-ES-----A-LSVETLLDVLVCLYTECSHSALRRDKYVAEFLE-WAKPFTQLVKEMQLHREDFEIIKVIGRGAFGEVAVVKM---K---N---TE----RIYAMKILNKWEMLKR-AETACFREERDVLV-N-G-DCQWITALHYAFQDENHLYLVMDYYVGGDLLTLLSK---FEDKLPED-MARFYIGEMVLAIDSIHQ-LHYVHRDIKPDNVLLDVNGHIRLADFGSCLKMNDDGTVQSSVAVGTPDYISPEILQAM--EDGMGKYGPECDWWSLGVCMYEMLYGETPFYAESL---VETYGKI----MNHEERFQFPS-HVTDVSEEAKDLIQRLIC-S-RER-RLG--Q---N--GIED----FKKHAFFEG--LNWENI--R--N--LEAPYIPDVSSPSDTSNFD-------------SHT-------GFSGLHLPFIGFTFTTESCFSDRGSL---KS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6 PsiBlast_PDB 80.1459%-120 - C2 -4UAL MRCKB_HUMAN A:[4-416] -SAKVRLKKLEQLLLDGPWRN-ES-----A-LSVETLLDVLVCLYTECSHSALRRDKYVAEFLE-WAKPFTQLVKEMQLHREDFEIIKVIGRGAFGEVAVVKM---K---N---TE----RIYAMKILNKWEMLKR-AETACFREERDVLV-N-G-DCQWITALHYAFQDENHLYLVMDYYVGGDLLTLLSK---FEDKLPED-MARFYIGEMVLAIDSIHQ-LHYVHRDIKPDNVLLDVNGHIRLADFGSCLKMNDDGTV---VAVGTPDYISPEILQAM--ED--GKYGPECDWWSLGVCMYEMLYGETPFYAESL---VETYGKI----MNHEERFQFPS-HVTDVSEEAKDLIQRLIC-S-RER-RLG--Q---N--GIED----FKKHAFFEG--LNWENI--R--N--LEAPYIPDVSSPSDTSNFDV-------ILPP--HT-------GFSGLHLPFIGFTFTTESCFSDRGSL---KS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3 PsiBlast_PDB 79.8059%-119 - C2 -3QFV MRCKB_HUMAN A:[2-414] -SAKVRLKKLEQLLLDGPWRN-ES-----A-LSVETLLDVLVCLYTECSHSALRRDKYVAEFLE-WAKPFTQLVKEMQLHREDFEIIKVIGRGAFGEVAVVKM---K---N---TE----RIYAMKILNKWEMLKR-AETACFREERDVLV-N-G-DCQWITALHYAFQDENHLYLVMDYYVGGDLLTLLSK---FEDKLPED-MARFYIGEMVLAIDSIHQ-LHYVHRDIKPDNVLLDVNGHIRLADFGSCLKMNDDGTVQSSVAVGTPDYISPEILQAM--EDGMGKYGPECDWWSLGVCMYEMLYGETPFYAESL---VETYGKI----MNHEERFQFPS-HVTDVSEEAKDLIQRLIC-S-RER-RLG--Q---N--GIED----FKKHAFFEG--LNWENI--R--N--LEAPYIPDVSSPSDTSNFDV------------------------SGLHLPFIGFTFTTESCFSDRGSL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
88 HHSearch 79.3162%-120 - C2 -4AW2 MRCKA_RAT A:[1-405] -SGEVRLRQLEQFILDGPAQTNGQ-----C-FSVETLLDILICLYDECNNSPLRREKNILEYLE-WAKPFTSKVKQMRLHREDFEILKVIGRGAFGEVAVVKL---K---N---AD----KVFAMKILNKWEMLKR-AETACFREERDVLV-N-G-DSKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSK---FEDRLPEE-MARFYLAEMVIAIDSVHQ-LHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGTPDYISPEILQAMEG--GKGRYGPECDWWSLGVCMYEMLYGETPFYAESL---VETYGKI----MNHKERFQFPT-QVTDVSENAKDLIRRLIC-S-REH-RLG--Q---N--GIED----FKKHPFFSG--IDWDNI--R--N--CEAPYIPEVSSPTDTSNFDVD-----------------------SGHHLPFVGFTY---TSSCVLSDR---SCLR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2 PsiBlast_PDB 78.9659%-116 - C2 -4AW2 MRCKA_RAT A:[1-416] -SGEVRLRQLEQFILDG-----PAQTNGQC-FSVETLLDILICLYDECNNSPLRREKNILEYLE-WAKPFTSKVKQMRLHREDFEILKVIGRGAFGEVAVVKL---K---N---AD----KVFAMKILNKWEMLKR-AETACFREERDVLV-N-G-DSKWITTLHYAFQDDNNLYLVMDYYVGGDLLTLLSK---FEDRLPEE-MARFYLAEMVIAIDSVHQ-LHYVHRDIKPDNILMDMNGHIRLADFGSCLKLMEDGTVQSSVAVGTPDYISPEILQAMEGGK--GRYGPECDWWSLGVCMYEMLYGETPFYAESL---VETYGKI----MNHKERFQFPT-QVTDVSENAKDLIRRLIC-S-REH-RLG--Q---N--GIED----FKKHPFFSG--IDWDNI--R--N--CEAPYIPEVSSPTDTSNFDVD-----------------------SGHHLPFVGFTYT--SSCVLSDRSCLR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22 PsiBlast_CBE 77.4259%-115 - C2 -3QFV MRCKB_HUMAN B:[2-414] -SAKVRLKKLEQLLLDGPWRN-ES-----A-LSVETLLDVLVCLYTECSHSALRRDKYVAEFLE-WAKPFTQLVKEMQLHREDFEIIKVIGRGAFGEVAVVKM---K---N---TE----RIYAMKILNKWEMLKR-AETACFREERDVLV-N-G-DCQWITALHYAFQDENHLYLVMDYYVGGDLLTLLSK---FEDKLPED-MARFYIGEMVLAIDSIHQ-LHYVHRDIKPDNVLLDVNGHIRLADFGSCLKMNDDGTVQSSVAVGTPDYISPEILQAM--EDGMGKYGPECDWWSLGVCMYEMLYGETPFYAESL---VETYGKI----MNHEERFQFPS-HVTDVSEEAKDLIQRLIC-S-RER-RLG--Q---N--GIED----FKKHAFFEG--LNWENI--R--N--LEAPYIPDVSSPSDTSNFD-----------------------GFSGLHLPFIGFTFTTESCFSDRGSL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23 PsiBlast_CBE 77.1959%-115 - C2 -3TKU MRCKB_HUMAN B:[18-430] -SAKVRLKKLEQLLLDGPWRN-ES-----A-LSVETLLDVLVCLYTECSHSALRRDKYVAEFLE-WAKPFTQLVKEMQLHREDFEIIKVIGRGAFGEVAVVKM---K---N---TE----RIYAMKILNKWEMLKR-AETACFREERDVLV-N-G-DCQWITALHYAFQDENHLYLVMDYYVGGDLLTLLSK---FEDKLPED-MARFYIGEMVLAIDSIHQ-LHYVHRDIKPDNVLLDVNGHIRLADFGSCLKMNDDGTVQSSVAVGTPDYISPEILQAM--EDGMGKYGPECDWWSLGVCMYEMLYGETPFYAESL---VETYGKI----MNHEERFQFPS-HVTDVSEEAKDLIQRLIC-S-RER-RLG--Q---N--GIED----FKKHAFFEG--LNWENI--R--N--LEAPYIPDVSSPSDTSNFD------------------------FSGLHLPFIGFTFTTESCFSDRGSL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4 PsiBlast_PDB 76.7559%-113 - C2 -3TKU MRCKB_HUMAN A:[18-430] -SAKVRLKKLEQLLLDGPWRN-ES-----A-LSVETLLDVLVCLYTECSHSALRRDKYVAEFLE-WAKPFTQLVKEMQLHREDFEIIKVIGRGAFGEVAVVKM---K---N---TE----RIYAMKILNKWEMLKR-AETACFREERDVLV-N-G-DCQWITALHYAFQDENHLYLVMDYYVGGDLLTLLSK---FEDKLPED-MARFYIGEMVLAIDSIHQ-LHYVHRDIKPDNVLLDVNGHIRLADFGSCLKMNDDGTVQSSVAVGTPDYISPEILQAM--EDGMGKYGPECDWWSLGVCMYEMLYGETPFYAESL---VETYGKI----MNHEERFQFPS-HVTDVSEEAKDLIQRLIC-S-RER-RLG--Q---N--GIED----FKKHAFFEG--LNWENI--R--N--LEAPYIPDVSSPSDTSNFDV------------------------SGLHLPFIGFTFTTESCFSDRGSL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13 PsiBlast_PDB 73.3244%-119 - C2 -4YVC ROCK1_HUMAN A:[6-399] -SFETRFEKMDNLLRD------PK-----SEVNSDCLLDGLDALVYDLDFPALRKNKNIDNFLS-RYKDTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRH---K---S---TR----KVYAMKLLSKFEMIK------FFWEERDIMA-F-A-NSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSN---YD--VPEK-WARFYTAEVVLALDAIHS-MGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDYISPEVLKSQGGD---GYYGRECDWWSVGVFLYEMLVGDTPFYADSL---VGTYSKI----MNHKNSLTFP--DDNDISKEAKNLICAFLT-D-REV-RLG--R---N--GVEE----IKRHLFFKNDQWAWETL--R--D--TVAPVVPDLSSDIDTSNFDDL------------ETFPIPK--AFVGNQLPFVGFTY---YSNRRY-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
54 PsiBlast_CBE 73.2243%-117 - C2 -2F2U ROCK2_BOVIN B:[12-400] ------QRKLEALIRD------PR-----SPINVESLLDGLNSLVLDLDFPALRKNKNIDNFLN-RYEKIVKKIRGLQMKAEDYDVVKVIGRGAFGEVQLVRH---K---A---SQ----KVYAMKLLSKFEMIKR-SDSAFFWEERDIMA-F-A-NSPWVVQLFCAFQDDKYLYMVMEYMPGGDLVNLMSN---YD--VPEK-WAKFYTAEVVLALDAIHS-MGLIHRDVKPDNMLLDKHGHLKLADFGTCMKMDETGMVHCDTAVGTPDYISPEVLKSQG---GDGYYGRECDWWSVGVFLFEMLVGDTPFYADSL---VGTYSKI----MDHKNSLCFP--EDAEISKHAKNLICAFLT-D-REV-RLG--R---N--GVEE----IKQHPFFKNDQWNWDNI--R--E--TAAPVVPELSSDIDSSNFDDI-------------TFPIPK--AFVGNQLPFIGFTY---YR---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
55 PsiBlast_CBE 72.8643%-120 - C2 -2F2U ROCK2_BOVIN A:[12-400] ------QRKLEALIRD------PR-----SPINVESLLDGLNSLVLDLDFPALRKNKNIDNFLN-RYEKIVKKIRGLQMKAEDYDVVKVIGRGAFGEVQLVRH---K---A---SQ----KVYAMKLLSKFEMIKR-SDSAFFWEERDIMA-F-A-NSPWVVQLFCAFQDDKYLYMVMEYMPGGDLVNLMSN---YD--VPEK-WAKFYTAEVVLALDAIHS-MGLIHRDVKPDNMLLDKHGHLKLADFGTCMKMDETGMVHCDTAVGTPDYISPEVLKSQG---GDGYYGRECDWWSVGVFLFEMLVGDTPFYADSL---VGTYSKI----MDHKNSLCFP--EDAEISKHAKNLICAFLT-D-REV-RLG--R---N--GVEE----IKQHPFFKNDQWNWDNI--R--E--TAAPVVPELSSDIDSSNFDDIE----------VETFPIPK--AFVGNQLPFIGFTY---YR---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26 PsiBlast_CBE 72.6844%-117 - C2 -4YVC ROCK1_HUMAN B:[5-399] MSFETRFEKMDNLLRD------PK-----SEVNSDCLLDGLDALVYDLDFPALRKNKNIDNFLS-RYKDTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRH---K---S---TR----KVYAMKLLSKFEMIKR-SDSAFFWEERDIMA-F-A-NSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSN---YD--VPEK-WARFYTAEVVLALDAIHS-MGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDYISPEVLKSQGGD---GYYGRECDWWSVGVFLYEMLVGDTPFYADSL---VGTYSKI----MNHKNSLTFP--DDNDISKEAKNLICAFLT-D-REV-RLG--R---N--GVEE----IKRHLFFKNDQWAWETL--R--D--TVAPVVPDLSSDIDTSNFDDL-----------EETFPIPK--AFVGNQLPFVGFTY---YSN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33 PsiBlast_CBE 72.2144%-114 - C2 -2ETK ROCK1_HUMAN B:[5-399] MSFETRFEKMDNLLRD------PK-----SEVNSDCLLDGLDALVYDLDFPALRKNKNIDNFLS-RYKDTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRH---K---S---TR----KVYAMKLLSKFEMIKR-SDSAFFWEERDIMA-F-A-NSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSN---YD--VPEK-WARFYTAEVVLALDAIHS-MGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDYISPEVLKSQGGD---GYYGRECDWWSVGVFLYEMLVGDTPFYADSL---VGTYSKI----MNHKNSLTFP--DDNDISKEAKNLICAFLT-D-REV-RLG--R---N--GVEE----IKRHLFFKNDQWAWETL--R--D--TVAPVVPDLSSDIDTSNFDDLEED-----KGEEETFPIPK--AFVGNQLPFVGFTY---YSN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14 PsiBlast_PDB 72.0644%-120 - C2 -4YVE ROCK1_HUMAN A:[6-399] -SFETRFEKMDNLLRD------PK-----SEVNSDCLLDGLDALVYDLDFPALRKNKNIDNFLS-RYKDTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRH---K---S---TR----KVYAMKLLSKFEMIKR-SDSAFFWEERDIMA-F-A-NSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSN---YD--VPEK-WARFYTAEVVLALDAIHS-MGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDYISPEVLKS-------GYYGRECDWWSVGVFLYEMLVGDTPFYADSL---VGTYSKI----MNHKNSLTFP--DDNDISKEAKNLICAFLT-D-REV-RLG--R---N--GVEE----IKRHLFFKNDQWAWETL--R--D--TVAPVVPDLSSDIDTSNFDDL-----------EETFPIPK--AFVGNQLPFVGFTY---YSNRRY-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15 PsiBlast_PDB 71.8944%-120 - C2 -5BML ROCK1_HUMAN A:[6-399] -SFETRFEKMDNLLRD------PK-----SEVNSDCLLDGLDALVYDLDFPALRKNKNIDNFLS-RYKDTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRH---K---S---TR----KVYAMKLLSKFEMIKR-SDSAFFWEERDIMA-F-A-NSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSN---YD--VPEK-WARFYTAEVVLALDAIHS-MGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDYISPEVLKSQGGD---GYYGRECDWWSVGVFLYEMLVGDTPFYADSL---VGTYSKI----MNHKNSLTFP--D--DISKEAKNLICAFLT-D-REV-RLG--R---N--GVEE----IKRHLFFKNDQWAWETL--R--D--TVAPVVPDLSSDIDTSNFDDL----------EEETFPIPK--AFVGNQLPFVGFTY---YSNRRY-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34 PsiBlast_CBE 71.8344%-114 - C2 -2ESM ROCK1_HUMAN B:[5-399] MSFETRFEKMDNLLRD------PK-----SEVNSDCLLDGLDALVYDLDFPALRKNKNIDNFLS-RYKDTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRH---K---S---TR----KVYAMKLLSKFEMIKR-SDSAFFWEERDIMA-F-A-NSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSN---YD--VPEK-WARFYTAEVVLALDAIHS-MGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDYISPEVLKSQGGD---GYYGRECDWWSVGVFLYEMLVGDTPFYADSL---VGTYSKI----MNHKNSLTFP--DDNDISKEAKNLICAFLT-D-REV-RLG--R---N--GVEE----IKRHLFFKNDQWAWETL--R--D--TVAPVVPDLSSDIDTSNFDDLEED-----KGEEETFPIPK--AFVGNQLPFVGFTY---YSN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24 PsiBlast_CBE 71.8244%-117 - C2 -5BML ROCK1_HUMAN B:[5-399] MSFETRFEKMDNLLRD------PK-----SEVNSDCLLDGLDALVYDLDFPALRKNKNIDNFLS-RYKDTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRH---K---S---TR----KVYAMKLLSKFEMIKR-SDSAFFWEERDIMA-F-A-NSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSN---YD--VPEK-WARFYTAEVVLALDAIHS-MGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDYISPEVLKSQGGD---GYYGRECDWWSVGVFLYEMLVGDTPFYADSL---VGTYSKI----MNHKNSLTFP--DDNDISKEAKNLICAFLT-D-REV-RLG--R---N--GVEE----IKRHLFFKNDQWAWETL--R--D--TVAPVVPDLSSDIDTSNFDDLEE--------EEETFPIPK--AFVGNQLPFVGFTY---YSN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31 PsiBlast_CBE 71.7344%-116 - C2 -3D9V ROCK1_HUMAN B:[5-399] MSFETRFEKMDNLLRD------PK-----SEVNSDCLLDGLDALVYDLDFPALRKNKNIDNFLS-RYKDTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRH---K---S---TR----KVYAMKLLSKFEMIKR-SDSAFFWEERDIMA-F-A-NSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSN---YD--VPEK-WARFYTAEVVLALDAIHS-MGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDYISPEVLKSQGGD---GYYGRECDWWSVGVFLYEMLVGDTPFYADSL---VGTYSKI----MNHKNSLTFP--DDNDISKEAKNLICAFLT-D-REV-RLG--R---N--GVEE----IKRHLFFKNDQWAWETL--R--D--TVAPVVPDLSSDIDTSNFDDLEED-----KGEEETFPIPK--AFVGNQLPFVGFTY---YSN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9 PsiBlast_PDB 71.7144%-116 - C2 -2ETR ROCK1_HUMAN A:[6-399] -SFETRFEKMDNLLRD------PK-----SEVNSDCLLDGLDALVYDLDFPALRKNKNIDNFLS-RYKDTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRH---K---S---TR----KVYAMKLLSKFEMIKR-SDSAFFWEERDIMA-F-A-NSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSN---YD--VPEK-WARFYTAEVVLALDAIHS-MGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDYISPEVLKSQGGD---GYYGRECDWWSVGVFLYEMLVGDTPFYADSL---VGTYSKI----MNHKNSLTFP--DDNDISKEAKNLICAFLT-D-REV-RLG--R---N--GVEE----IKRHLFFKNDQWAWETL--R--D--TVAPVVPDLSSDIDTSNFDDLEED-----KGEEETFPIPK--AFVGNQLPFVGFTY---YSNRRY-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32 PsiBlast_CBE 71.6544%-115 - C2 -2ETR ROCK1_HUMAN B:[5-399] MSFETRFEKMDNLLRD------PK-----SEVNSDCLLDGLDALVYDLDFPALRKNKNIDNFLS-RYKDTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRH---K---S---TR----KVYAMKLLSKFEMIKR-SDSAFFWEERDIMA-F-A-NSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSN---YD--VPEK-WARFYTAEVVLALDAIHS-MGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDYISPEVLKSQGGD---GYYGRECDWWSVGVFLYEMLVGDTPFYADSL---VGTYSKI----MNHKNSLTFP--DDNDISKEAKNLICAFLT-D-REV-RLG--R---N--GVEE----IKRHLFFKNDQWAWETL--R--D--TVAPVVPDLSSDIDTSNFDDLEED-----KGEEETFPIPK--AFVGNQLPFVGFTY---YSN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
48 PsiBlast_CBE 71.0643%-121 - C2 -4L6Q ROCK2_HUMAN A:[12-400] ------QRKLEALIRD------PR-----SPINVESLLDGLNSLVLDLDFPALRKNKNIDNFLN-RYEKIVKKIRGLQMKAEDYDVVKVIGRGAFGEVQLVRH---K---A---SQ----KVYAMKLLSKFEMIKR-SDSAFFWEERDIMA-F-A-NSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSN---YD--VPEK-WAKFYTAEVVLALDAIHS-MGLIHRDVKPDNMLLDKHGHLKLADFGTCMKMDETGMVHCDTAVGTPDYISPEVLKSQG---GDGFYGRECDWWSVGVFLYEMLVGDTPFYADSL---VGTYSKI----MDHKNSLCFP--EDAEISKHAKNLICAFLT-D-REV-RLG--R---N--GVEE----IRQHPFFKNDQWHWDNI--R--E--TAAPVVPELSSDIDSSNFDDIEDD--------VETFPIPK--AFVGNQLPFIGFTY---YR---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10 PsiBlast_PDB 71.0544%-118 - C2 -3D9V ROCK1_HUMAN A:[6-399] -SFETRFEKMDNLLRD------PK-----SEVNSDCLLDGLDALVYDLDFPALRKNKNIDNFLS-RYKDTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRH---K---S---TR----KVYAMKLLSKFEMIKR-SDSAFFWEERDIMA-F-A-NSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSN---YD--VPEK-WARFYTAEVVLALDAIHS-MGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDYISPEVLKSQGGD---GYYGRECDWWSVGVFLYEMLVGDTPFYADSL---VGTYSKI----MNHKNSLTFP--DDNDISKEAKNLICAFLT-D-REV-RLG--R---N--GVEE----IKRHLFFKNDQWAWETL--R--D--TVAPVVPDLSSDIDTSNFDDLEED-----KGEEETFPIPK--AFVGNQLPFVGFTY---YSNRRY-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25 PsiBlast_CBE 70.9844%-119 - C2 -4YVE ROCK1_HUMAN B:[5-399] MSFETRFEKMDNLLRD------PK-----SEVNSDCLLDGLDALVYDLDFPALRKNKNIDNFLS-RYKDTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRH---K---S---TR----KVYAMKLLSKFEMIKR-SDSAFFWEERDIMA-F-A-NSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSN---YD--VPEK-WARFYTAEVVLALDAIHS-MGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDYISPEVLKSQGGD---GYYGRECDWWSVGVFLYEMLVGDTPFYADSL---VGTYSKI----MNHKNSLTFP--DDNDISKEAKNLICAFLT-D-REV-RLG--R---N--GVEE----IKRHLFFKNDQWAWETL--R--D--TVAPVVPDLSSDIDTSNFDDL----------EEETFPIPK--AFVGNQLPFVGFTY---YSN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
47 PsiBlast_CBE 70.8443%-116 - C2 -4L6Q ROCK2_HUMAN B:[12-400] ------QRKLEALIRD------PR-----SPINVESLLDGLNSLVLDLDFPALRKNKNIDNFLN-RYEKIVKKIRGLQMKAEDYDVVKVIGRGAFGEVQLVRH---K---A---SQ----KVYAMKLLSKFEMIKR-SDSAFFWEERDIMA-F-A-NSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSN---YD--VPEK-WAKFYTAEVVLALDAIHS-MGLIHRDVKPDNMLLDKHGHLKLADFGTCMKMDETGMVHCDTAVGTPDYISPEVLKSQG---GDGFYGRECDWWSVGVFLYEMLVGDTPFYADSL---VGTYSKI----MDHKNSLCFP--EDAEISKHAKNLICAFLT-D-REV-RLG--R---N--GVEE----IRQHPFFKNDQWHWDNI--R--E--TAAPVVPELSSDIDSSNFDDIEDD--------VETFPIPK--AFVGNQLPFIGFTY---YR---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7 PsiBlast_PDB 70.7144%-115 - C2 -2ESM ROCK1_HUMAN A:[6-399] -SFETRFEKMDNLLRD------PK-----SEVNSDCLLDGLDALVYDLDFPALRKNKNIDNFLS-RYKDTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRH---K---S---TR----KVYAMKLLSKFEMIKR-SDSAFFWEERDIMA-F-A-NSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSN---YD--VPEK-WARFYTAEVVLALDAIHS-MGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDYISPEVLKSQGGD---GYYGRECDWWSVGVFLYEMLVGDTPFYADSL---VGTYSKI----MNHKNSLTFP--DDNDISKEAKNLICAFLT-D-REV-RLG--R---N--GVEE----IKRHLFFKNDQWAWETL--R--D--TVAPVVPDLSSDIDTSNFDDLEED-----KGEEETFPIPK--AFVGNQLPFVGFTY---YSNRRY-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
53 PsiBlast_CBE 70.5643%-109 - C2 -2H9V ROCK2_BOVIN A:[11-400] -----RQRKLEALIRD------PR-----SPINVESLLDGLNSLVLDLDFPALRKNKNIDNFLN-RYEKIVKKIRGLQMKAEDYDVVKVIGRGAFGEVQLVRH---K---A---SQ----KVYAMKLLSKFEMIKR-SDSAFFWEERDIMA-F-A-NSPWVVQLFCAFQDDKYLYMVMEYMPGGDLVNLMSN---YD--VPEK-WAKFYTAEVVLALDAIHS-MGLIHRDVKPDNMLLDKHGHLKLADFGTCMKMDETGMVHCDTAVGTPDYISPEVLKSQG---GDGYYGRECDWWSVGVFLFEMLVGDTPFYADSL---VGTYSKI----MDHKNSLCFP--EDAEISKHAKNLICAFLT-D-REV-RLG--R---N--GVEE----IKQHPFFKNDQWNWDNI--R--E--TAAPVVPELSSDIDSSNFDDIE---------------IPK--AFVGNQLPFIGFTY---YR---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8 PsiBlast_PDB 70.1144%-118 - C2 -2ETK ROCK1_HUMAN A:[6-399] -SFETRFEKMDNLLRD------PK-----SEVNSDCLLDGLDALVYDLDFPALRKNKNIDNFLS-RYKDTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRH---K---S---TR----KVYAMKLLSKFEMIKR-SDSAFFWEERDIMA-F-A-NSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSN---YD--VPEK-WARFYTAEVVLALDAIHS-MGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDYISPEVLKSQGGD---GYYGRECDWWSVGVFLYEMLVGDTPFYADSL---VGTYSKI----MNHKNSLTFP--DDNDISKEAKNLICAFLT-D-REV-RLG--R---N--GVEE----IKRHLFFKNDQWAWETL--R--D--TVAPVVPDLSSDIDTSNFDDLEED-----KGEEETFPIPK--AFVGNQLPFVGFTY---YSNRRY-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20 PsiBlast_PDB 69.1144%-113 - C2 -2V55 ROCK1_HUMAN A:[6-399] -SFETRFEKMDNLLRD------PK-----SEVNSDCLLDGLDALVYDLDFPALRKNKNIDNFLS-RYKDTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRH---K---S---TR----KVYAMKLLSKFEMIKR-SDSAFFWEERDIMA-F-A-NSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSN---YD--VPEK-WARFYTAEVVLALDAIHS-MGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDYISPEVLKSQGGD---GYYGRECDWWSVGVFLYEMLVGDTPFYADSL---VGTYSKI----MNHKNSLTFP--DDNDISKEAKNLICAFLT-D-REV-RLG--R---N--GVEE----IKRHLFFKNDQWAWETL--R--D--TVAPVVPDLSSDIDTSNFDDL-----------EETFPIPK--AFVGNQLPFVGFTY---YSNRR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
91 HHSearch 61.8840%-115 * C2 *4GV1 AKT1_HUMAN A:[4-300] -----------------------------------------------------------------------------RVTMNEFEYLKLLGKGTFGKVILVKE---K---A---TG----RYYAMKILKKEVIVAK-DEVAHTLTENRVLQ-N-S-RHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSR---E-RVFSED-RARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMK-TFCGTPEYLAPEVLED-------NDYGRAVDWWGLGVVMYEMMCGRLPFYNQDH---EKLFELI----LM--EEIRFP----RTLGPEAKSLLSGLLK-KDPKQ-RLG--GGS-E--DAKE----IMQHRFFAG--IVWQHV--Y--EKKLSPPFKPQVTSETDTRYFDEEFTAQMITITPSMECVDSERRPHFPQFDYSAS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
94 HHSearch 61.6437%-111 - C2 -1RDQ KAPCA_MOUSE E:[37-332] -----------------------------------------------------------------------------TAQLDQFDRIKTLGTGSFGRVMLVKH---K---E---SG----NHYAMKILDKQKVVKL-KQIEHTLNEKRILQ-A-V-NFPFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRR---IG-RFSEP-HARFYAAQIVLTFEYLHS-LDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGR----TWTLCGTPEALAPEIILS-------KGYNKAVDWWALGVLIYEMAAGYPPFFADQP---IQIYEKI----VSGK--VRFP----SHFSSDLKDLLRNLLQVD-LTK-RFGNLK---N--GVND----IKNHKWFAT--TDWIAI--YQRK--VEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
104 HHSearch 60.1638%-108 - C2 -3WF7 KS6B1_HUMAN A:[15-304] -----------------------------------------------------------------------------KIRPECFELLRVLGKGGYGKVFQVRKVTGA---N---TG----KIFAMKVLKKAMIVRNAKDTAHTKAERNILE-E-V-KHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLER---EG-IFMED-TACFYLAEISMALGHLHQ-KGIIYRDLKPENIMLNHQGHVKLTDFGLCKESIHD---TH-TFCGTIEYMAPEILMR-------SGHNRAVDWWSLGALMYDMLTGAPPFTGENR---KKTIDKI----LKC--KLNLP----PYLTQEARDLLKKLLKRN-AAS-RLG--A---GPGDAGE----VQAHPFFRH--INWEELLAR--K--VEPPFKPLLQ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
60 PsiBlast_CBE 59.0135%-103 - C2 -2F7X KAPCA_BOVIN E:[16-333] ------------------------------------------------VKEFLAKAK--EDFLKKWENPA-----QNTAHLDQFERIKTLGTGSFGRVMLVKH---M---E---TG----NHYAMKILDKQKVVKL-KQIEHTLNEKRILQ-A-V-NFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRR---IG-RFSEP-HARFYAAQIVLTFEYLHS-LDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKG----RTWTLCGTPEYLAPEIILSKG-------YNKAVDWWALGVLIYEMAAGYPPFFADQP---IQIYEKIVSGKVRFPSHFSSDL----------KDLLRNLLQ-V-DLTKRFGNLK---N--GVND----IKNHKWFAT--TDWIAIYQR--K--VEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------