@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : MKNK1_HUMAN: (2015-10-14 )
MVSSQKLEKPIEMGSSEPLPIADGDRRRKKKRRGRATDSLPGKFEDMYKLTSELLGEGAYAKVQGAVSLQNGKEYAVKIIEKQAGHSRSRVFREVETLYQCQGNKNILELIEFFEDDTRFYLVFEKLQGGSILAHIQKQKHFNEREASRVVRDVAAALDFLHTKDKVSLCHLGWSAMAPSGLTAAPTSLGSSDPPTSASQVAGTTGIAHRDLKPENILCESPEKVSPVKICDFDLGSGMKLNNSCTPITTPELTTPCGSAEYMAPEVVEVFTDQATFYDKRCDLWSLGVVLYIMLSGYPPFVGHCGADCGWDRGEVCRVCQNKLFESIQEGKYEFPDKDWAHISSEAKDLISKLLVRDAKQRLSAAQVLQHPWVQGQAPEKGLPTPQVLQRNSSTMDLTLFAAEAIALNRQLSQHEENELAEEPEALADGLCSMKLSPPCKSRLARRRALAQAGRGEDRSPPTAL
Atome Classification :
(14 SA)
.........10........20........30........40........50........60........70........80.......--.---90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210......-.220.....--..230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370...--....380.......390.......400--.........410.......420.......430.......440.......450.......460...
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MV
S
S
Q
K
L
E
K
P
I
EMGSSEPLPIAD
G
D
R
R
R
K
K
K
RRGRATDSLP
G
K
F
E
D
M
Y
K
L
T
S
E
L
LGEGA
Y
A
K
V
Q
G
A
V
S
LQNG
K
E
Y
A
V
K
I
I
E
K
QAG
H
S
R
--
S
---
R
V
F
R
E
V
E
T
L
Y
QCQGNK
N
I
L
E
L
I
E
F
FEDD
T
R
F
Y
L
V
F
EKLQG
G
S
I
L
A
H
I
Q
K
Q
KHF
N
E
R
E
A
S
R
V
V
R
D
V
A
A
A
L
D
F
LHTKDK
V
S
L
C
HLGWSAMAPSGLTAAPTSLGSSDPPTS
A
S
QVAGTTGIAHRDLKPENIL-CESPEKVS
P
--
V
K
I
C
D
FDLGSGMKLNNSCTPITTPELTTPCGSAEYM
A
P
E
V
V
E
V
FTDQA
T
F
Y
D
KRC
D
L
W
S
L
G
V
V
L
Y
I
M
LSGYPPFVGHCGADCGW
D
R
G
E
V
C
R
V
C
Q
N
K
L
F
E
S
I
Q
EGKYEFPD
K
D
W
A
H
I
S
S
E
A
K
D
L
I
S
K
L
L
V
R
D
A
K
Q
R
L
S
A
A
Q
V
L
QHPWVQ--GQAPEKGLP
T
P
Q
V
L
QRNSS
T
M
D
L
T
L
----
F
A
A
E
A
I
A
L
N
R
Q
L
S
Q
H
E
E
N
E
L
AE
E
P
E
A
L
A
D
G
L
C
SMKLSP
P
C
K
S
R
L
A
R
R
R
A
L
A
QAGRGEDRSPPTAL
3
PsiBlast_PDB
88.48
68%
-110
- C1 -
2HW7
1
MKNK2_HUMAN
A:
[2-302]
-----------------------------------
S
T
D
S
F
S
G
R
F
E
D
V
Y
Q
L
Q
E
D
V
L
G
E
G
A
H
A
R
V
Q
T
C
I
N
L
I
T
S
Q
E
Y
A
V
K
I
I
E
K
Q
P
G
H
I
R
--
S
---
R
V
F
R
E
V
E
M
L
Y
Q
C
Q
G
H
R
N
V
L
E
L
I
E
F
F
E
E
E
D
R
F
Y
L
V
F
E
K
M
R
G
G
S
I
L
S
H
I
H
K
R
R
H
F
N
E
L
E
A
S
V
V
V
Q
D
V
A
S
A
L
D
F
L
H
N
K
-----------------------------------------
G
I
A
H
R
D
L
K
P
E
N
I
L
-
C
E
H
P
N
Q
V
S
P
--
V
K
I
C
D
F
G
-----------------------
G
S
A
E
Y
M
A
P
E
V
V
E
A
F
S
E
E
A
S
I
Y
D
K
R
C
D
L
W
S
L
G
V
I
L
Y
I
L
L
S
G
Y
P
P
F
V
G
R
C
---
C
G
-----
A
C
P
A
C
Q
N
M
L
F
E
S
I
Q
E
G
K
Y
E
F
P
D
K
D
W
A
H
I
S
C
A
A
K
D
L
I
S
K
L
L
V
R
D
A
K
Q
R
L
S
A
A
Q
V
L
Q
H
P
W
V
Q
--
G
C
--------------------------------------------------------------------------------------------
9
PsiBlast_PDB
70.01
32%
-88
- C1 -
2WEI
1
?
A:
[10-286]
---------------------------------
G
R
E
N
L
Y
F
Q
G
T
F
A
E
R
Y
N
I
V
C
-
M
L
G
K
G
S
F
G
E
V
L
K
C
K
D
R
I
T
Q
Q
E
Y
A
V
K
V
I
N
K
A
S
A
K
N
K
D
T
S
---
T
I
L
R
E
V
E
L
L
K
K
L
D
-
H
P
N
I
M
K
L
F
E
I
L
E
D
S
S
S
F
Y
I
V
G
E
L
Y
T
G
G
E
L
F
D
E
I
I
K
R
K
R
F
S
E
H
D
A
A
R
I
I
K
Q
V
F
S
G
I
T
Y
M
H
K
H
N
-----------------------------------------
I
V
H
R
D
L
K
P
E
N
I
L
-
L
E
S
K
E
K
D
C
D
--
I
K
I
I
D
F
G
L
S
T
C
F
Q
Q
N
T
--------
K
M
K
D
R
I
G
T
A
Y
Y
I
A
P
E
V
L
-----
R
G
T
-
Y
D
E
K
C
D
V
W
S
A
G
V
I
L
Y
I
L
L
S
G
T
P
P
F
Y
G
K
N
E
Y
D
---------------
I
L
K
R
V
E
T
G
K
Y
A
F
D
L
P
Q
W
R
T
I
S
D
D
A
K
D
L
I
R
K
M
L
T
F
H
P
S
L
R
I
T
A
T
Q
C
L
E
H
P
W
I
Q
--
K
Y
S
S
E
-----------------------------------------------------------------------------------------
36
PsiBlast_CBE
66.52
32%
-93
- C1 -
3MA6
1
?
A:
[30-296]
-------------------------------------------
F
S
D
R
Y
K
-
G
Q
R
V
L
G
K
G
S
F
G
E
V
I
L
C
K
D
K
I
T
G
Q
E
C
A
V
K
V
I
S
K
R
Q
V
K
Q
K
--
T
D
K
E
S
L
L
R
E
V
Q
L
L
K
Q
L
D
-
H
P
N
I
M
K
L
Y
E
F
F
E
D
K
G
Y
F
Y
L
V
G
E
V
Y
T
G
G
E
L
F
D
E
I
I
S
R
K
R
F
S
E
V
D
A
A
R
I
I
R
Q
V
L
S
G
I
T
Y
M
H
-
K
N
K
----------------------------------------
I
V
H
R
D
L
K
P
E
N
L
L
-
L
E
S
K
S
K
D
A
N
--
I
R
I
I
D
F
G
L
S
T
H
F
E
---------
S
K
K
M
K
D
K
I
G
T
A
Y
Y
I
A
P
E
V
L
H
------
G
T
Y
D
E
K
C
D
V
W
S
T
G
V
I
L
Y
I
L
L
S
G
C
P
P
F
N
G
A
N
E
Y
D
---------------
I
L
K
K
V
E
K
G
K
Y
T
F
E
L
P
Q
W
K
K
V
S
E
S
A
K
D
L
I
R
K
M
L
T
Y
V
P
S
M
R
I
S
A
R
D
A
L
D
H
E
W
I
Q
--
T
Y
T
K
------------------------------------------------------------------------------------------
42
PsiBlast_CBE
66.18
31%
-107
- C1 -
4FG8
1
KCC1A_HUMAN
B:
[18-278]
---------------------------------------------
D
I
Y
D
F
-
R
D
V
L
G
T
G
A
F
S
E
V
I
L
A
E
D
K
R
T
Q
K
L
V
A
I
K
C
I
A
K
---------------
N
E
I
A
V
L
H
K
I
K
-
H
P
N
I
V
A
L
D
D
I
Y
E
S
G
G
H
L
Y
L
I
M
Q
L
V
S
G
G
E
L
F
D
R
I
V
E
K
G
F
Y
T
E
R
D
A
S
R
L
I
F
Q
V
L
D
A
V
K
Y
L
H
D
-----------------------------------------
L
G
I
V
H
R
D
L
K
P
E
N
L
L
-
Y
Y
S
L
D
E
D
S
K
--
I
M
I
S
D
F
G
--------
G
S
V
-------
L
S
T
A
C
G
T
P
G
Y
V
A
P
E
V
L
-----
A
Q
K
P
Y
S
K
A
V
D
C
W
S
I
G
V
I
A
Y
I
L
L
C
G
Y
P
P
F
Y
D
E
N
D
A
---------------
K
L
F
E
Q
I
L
K
A
E
Y
E
F
D
S
P
Y
W
D
D
I
S
D
S
A
K
D
F
I
R
H
L
M
E
K
D
P
E
K
R
F
T
C
E
Q
A
L
Q
H
P
W
I
A
--
G
D
T
A
L
D
K
N
I
H
Q
S
V
S
E
Q
I
K
K
N
F
A
------------------------------------------------------------------------
35
PsiBlast_CBE
65.56
32%
-92
- C1 -
3MA6
1
?
B:
[30-295]
-------------------------------------------
F
S
D
R
Y
K
-
G
Q
R
V
L
G
K
G
S
F
G
E
V
I
L
C
K
D
K
I
T
G
Q
E
C
A
V
K
V
I
S
K
R
Q
V
K
Q
---
T
DK
E
S
L
L
R
E
V
Q
L
L
K
Q
L
D
-
H
P
N
I
M
K
L
Y
E
F
F
E
D
K
G
Y
F
Y
L
V
G
E
V
Y
T
G
G
E
L
F
D
E
I
I
S
R
K
R
F
S
E
V
D
A
A
R
I
I
R
Q
V
L
S
G
I
T
Y
M
H
-
K
N
K
----------------------------------------
I
V
H
R
D
L
K
P
E
N
L
L
-
L
E
S
K
S
K
D
A
N
--
I
R
I
I
D
F
G
L
S
T
H
F
E
--------
A
S
K
K
M
K
D
K
I
G
T
A
Y
Y
I
A
P
E
V
L
H
------
G
T
Y
D
E
K
C
D
V
W
S
T
G
V
I
L
Y
I
L
L
S
G
C
P
P
F
N
G
A
N
E
Y
D
---------------
I
L
K
K
V
E
K
G
K
Y
T
F
E
L
P
Q
W
K
K
V
S
E
S
A
K
D
L
I
R
K
M
L
T
Y
V
P
S
M
R
I
S
A
R
D
A
L
D
H
E
W
I
Q
--
T
Y
T
-------------------------------------------------------------------------------------------
41
PsiBlast_CBE
65.23
31%
-104
- C1 -
4FG7
1
KCC1A_HUMAN
A:
[18-277]
---------------------------------------------
D
I
Y
D
F
-
R
D
V
L
G
T
G
A
F
S
E
V
I
L
A
E
D
K
R
T
Q
K
L
V
A
I
K
C
I
A
-------------
S
M
E
N
E
I
A
V
L
H
K
I
K
-
H
P
N
I
V
A
L
D
D
I
Y
E
S
G
G
H
L
Y
L
I
M
Q
L
V
S
G
G
E
L
F
D
R
I
V
E
K
G
F
Y
T
E
R
D
A
S
R
L
I
F
Q
V
L
D
A
V
K
Y
L
H
D
-----------------------------------------
L
G
I
V
H
R
D
L
K
P
E
N
L
L
-
Y
Y
S
L
D
E
D
S
K
--
I
M
I
S
D
F
G
L
-
S
K
M
E
D
P
---------------
G
T
P
G
Y
V
A
P
E
V
L
-----
A
Q
K
--
S
K
A
V
D
C
W
S
I
G
V
I
A
Y
I
L
L
C
G
Y
P
P
F
Y
D
E
N
D
A
---------------
K
L
F
E
Q
I
L
K
A
E
Y
E
F
D
S
P
Y
W
D
D
I
S
D
S
A
K
D
F
I
R
H
L
M
E
K
D
P
E
K
R
F
T
C
E
Q
A
L
Q
H
P
W
I
A
------------------------------------------------------------------------------------------------
43
PsiBlast_CBE
65.13
31%
-111
- C1 -
4FG8
1
KCC1A_HUMAN
A:
[18-278]
---------------------------------------------
D
I
Y
D
F
-
R
D
V
L
G
T
G
A
F
S
E
V
I
L
A
E
D
K
R
T
Q
K
L
V
A
I
K
C
I
A
K
E
--------------
N
E
I
A
V
L
H
K
I
K
-
H
P
N
I
V
A
L
D
D
I
Y
E
S
G
G
H
L
Y
L
I
M
Q
L
V
S
G
G
E
L
F
D
R
I
V
E
K
G
F
Y
T
E
R
D
A
S
R
L
I
F
Q
V
L
D
A
V
K
Y
L
H
D
-----------------------------------------
L
G
I
V
H
R
D
L
K
P
E
N
L
L
-
Y
Y
S
L
D
E
D
S
K
--
I
M
I
S
D
F
-------------------------
T
P
G
Y
V
A
P
E
V
L
-----
A
Q
K
P
Y
S
K
A
V
D
C
W
S
I
G
V
I
A
Y
I
L
L
C
G
Y
P
P
F
Y
D
E
N
D
A
---------------
K
L
F
E
Q
I
L
K
A
E
Y
E
F
D
S
P
Y
W
D
D
I
S
D
S
A
K
D
F
I
R
H
L
M
E
K
D
P
E
K
R
F
T
C
E
Q
A
L
Q
H
P
W
I
A
--
G
D
T
A
L
D
K
N
I
H
Q
S
V
S
E
Q
I
K
K
N
F
A
------------------------------------------------------------------------
14
PsiBlast_PDB
64.07
31%
-78
- C1 -
4D9U
1
A:
[19-316]
------------------------------------------
Q
F
T
D
G
Y
E
V
-
K
E
D
I
G
V
G
S
Y
S
V
C
K
R
C
I
H
K
A
T
N
M
E
F
A
V
K
I
I
D
K
----
S
K
--
R
---
D
P
T
E
E
I
E
I
L
L
R
Y
G
Q
H
P
N
I
I
T
L
K
D
V
Y
D
D
G
K
Y
V
Y
V
V
T
E
L
M
K
G
G
E
L
L
D
K
I
L
R
Q
K
F
F
S
E
R
E
A
S
A
V
L
F
T
I
T
K
T
V
E
Y
L
H
A
Q
-----------------------------------------
G
V
V
H
R
D
L
K
P
S
N
I
L
Y
V
D
E
S
G
N
P
E
S
--
I
R
I
C
D
F
G
F
A
K
Q
L
R
A
E
N
G
L
-------
L
M
T
P
C
Y
T
A
N
F
V
A
P
E
V
L
E
-----
R
Q
G
Y
D
A
A
C
D
I
W
S
L
G
V
L
L
Y
T
M
L
T
G
Y
T
P
F
A
N
--
G
P
D
---
D
T
P
E
-------
E
I
L
A
R
I
G
S
G
K
F
S
L
S
G
G
Y
W
N
S
V
S
D
T
A
K
D
L
V
S
K
M
L
H
V
D
P
H
Q
R
L
T
A
A
L
V
L
R
H
P
W
I
-----
V
H
W
D
Q
L
P
Q
Y
Q
L
N
R
Q
D
A
P
H
L
V
K
G
A
----
M
A
A
T
Y
S
A
L
N
R
N
Q
-----------------------------------------------------
16
PsiBlast_PDB
62.82
31%
-97
- C1 -
3KN5
1
KS6A5_HUMAN
A:
[19-291]
------------------------------------------------------
L
G
E
G
S
F
S
I
C
R
K
C
V
H
K
K
S
N
Q
A
F
A
V
K
I
I
S
K
R
M
---
E
--
A
---
N
T
Q
K
E
I
T
A
L
K
L
C
E
G
H
P
N
I
V
K
L
H
E
V
F
H
D
Q
L
H
T
F
L
V
M
E
L
L
N
G
G
E
L
F
E
R
I
K
K
K
K
H
F
S
E
T
E
A
S
Y
I
M
R
K
L
V
S
A
V
S
H
M
H
D
-----------------------------------------
V
G
V
V
H
R
D
L
K
P
E
N
L
L
-
F
T
D
----
L
E
--
I
K
I
I
D
F
G
F
A
R
-------
L
K
P
P
---------------------------
N
G
Y
D
E
S
C
D
L
W
S
L
G
V
I
L
Y
T
M
L
S
G
Q
V
P
F
Q
--------------
C
-
T
S
A
V
E
I
M
K
K
I
K
K
G
D
F
S
F
E
G
E
A
W
K
N
V
S
Q
E
A
K
D
L
I
Q
G
L
L
T
V
D
P
N
K
R
L
K
M
S
G
L
R
Y
N
E
W
L
Q
DG
S
Q
L
S
S
N
P
L
M
T
P
D
I
L
G
S
S
G
A
A
V
H
T
C
V
----
K
A
T
F
H
A
F
N
K
Y
K
R
E
G
---------------------------------------------------
15
PsiBlast_PDB
62.78
31%
-74
- C1 -
4D9T
1
A:
[19-315]
------------------------------------------
Q
F
T
D
G
Y
E
V
-
K
E
D
I
G
V
G
S
Y
S
V
C
K
R
C
I
H
K
A
T
N
M
E
F
A
V
K
I
I
D
K
----
S
K
--
R
---
D
P
T
E
E
I
E
I
L
L
R
Y
G
Q
H
P
N
I
I
T
L
K
D
V
Y
D
D
G
K
Y
V
Y
V
V
T
E
L
M
K
G
G
E
L
L
D
K
I
L
R
Q
K
F
F
S
E
R
E
A
S
A
V
L
F
T
I
T
K
T
V
E
Y
L
H
A
Q
-----------------------------------------
G
V
V
H
R
D
L
K
P
S
N
I
L
Y
V
D
E
S
G
N
P
E
S
--
I
R
I
C
D
F
G
F
A
K
Q
L
R
A
E
N
G
L
-------
L
M
T
P
C
Y
T
A
N
F
V
A
P
E
V
L
E
-----
R
Q
G
Y
D
A
A
C
D
I
W
S
L
G
V
L
L
Y
T
M
L
T
G
Y
T
P
F
A
N
--
G
P
D
---
D
T
P
E
-------
E
I
L
A
R
I
G
S
G
K
F
S
L
S
G
G
Y
W
N
S
V
S
D
T
A
K
D
L
V
S
K
M
L
H
V
D
P
H
Q
R
L
T
A
A
L
V
L
R
H
P
W
I
-----
V
H
W
D
Q
L
P
Q
Y
Q
L
N
R
Q
D
A
P
H
L
V
K
G
A
----
M
A
A
T
Y
S
A
L
N
R
N
------------------------------------------------------
24
PsiBlast_CBE
61.66
33%
-86
- C1 -
2WNT
2
B:
[26-317]
--------------------------------------------
S
D
G
Y
-
V
V
K
E
T
I
G
V
G
S
Y
S
E
C
K
R
C
V
H
K
A
T
N
M
E
Y
A
V
K
V
I
D
K
----
S
K
--
R
---
D
P
S
E
E
I
E
I
L
L
R
Y
G
Q
H
P
N
I
I
T
L
K
D
V
Y
D
D
G
K
H
V
Y
L
V
T
E
L
M
R
G
G
E
L
L
D
K
I
L
R
Q
K
F
F
S
E
R
E
A
S
F
V
L
H
T
I
G
K
T
V
E
Y
L
H
S
Q
-----------------------------------------
G
V
V
H
R
D
L
K
P
S
N
I
L
-
Y
V
D
-
E
S
G
N
P
EC
L
R
I
C
D
F
G
F
A
K
Q
L
R
A
E
N
G
L
-------
L
M
T
P
C
Y
---------------
K
R
Q
G
Y
D
E
G
C
D
I
W
S
L
G
I
L
L
Y
T
M
L
A
G
Y
T
P
F
-----
A
N
G
P
S
D
T
P
E
-------
E
I
L
T
R
I
G
S
G
K
F
T
L
S
G
G
N
W
N
T
V
S
E
T
A
K
D
L
V
S
K
M
L
H
V
D
P
H
Q
R
L
T
A
K
Q
V
L
Q
H
P
W
V
-----
T
Q
K
D
K
L
P
Q
S
Q
L
-----
S
H
Q
D
L
Q
L
V
K
G
A
M
A
A
T
Y
S
A
L
N
S
S
K
-----------------------------------------------------
40
PsiBlast_CBE
60.92
31%
-97
- C1 -
2JAM
3
KCC1G_HUMAN
A:
[15-269]
----------------------------------------------------
E
V
L
G
S
G
A
F
S
E
V
F
L
V
K
Q
R
L
T
G
K
L
F
A
L
K
C
I
K
K
S
-----------
S
L
E
N
E
I
A
V
L
K
K
I
K
-
H
E
N
I
V
T
L
E
D
I
Y
E
S
T
T
H
Y
Y
L
V
M
Q
L
V
S
G
G
E
L
F
D
R
I
L
E
R
G
V
Y
T
E
K
D
A
S
L
V
I
Q
Q
V
L
S
A
V
K
Y
L
H
E
-----------------------------------------
N
G
I
V
H
R
D
L
K
P
E
N
L
L
-
Y
L
T
P
E
E
N
S
K
--
I
M
I
T
D
F
G
L
-
S
K
M
E
Q
N
G
I
--------
M
S
T
A
C
G
T
P
G
Y
V
A
P
E
V
L
-----
A
Q
K
P
Y
S
K
A
V
D
C
W
S
I
G
V
I
T
Y
I
L
L
C
G
Y
P
P
F
Y
E
E
T
---------------
E
S
K
L
F
E
K
I
K
E
G
Y
Y
E
F
E
S
P
F
W
D
D
I
S
E
S
A
K
D
F
I
C
H
L
L
E
K
D
P
N
E
R
Y
T
C
E
K
A
L
S
H
P
W
I
D
--
G
N
T
A
L
H
R
D
I
Y
P
S
V
S
L
Q
I
Q
K
N
F
A
K
S
----------------------------------------------------------------------
25
PsiBlast_CBE
60.74
31%
-91
- C1 -
3KN5
1
B:
[19-291]
------------------------------------------------------
L
G
E
G
S
F
S
I
C
R
K
C
V
H
K
K
S
N
Q
A
F
A
V
K
I
I
S
K
R
M
---
E
--
A
---
N
T
Q
K
E
I
T
A
L
K
L
C
E
G
H
P
N
I
V
K
L
H
E
V
F
H
D
Q
L
H
T
F
L
V
M
E
L
L
N
G
G
E
L
F
E
R
I
K
K
K
K
H
F
S
E
T
E
A
S
Y
I
M
R
K
L
V
S
A
V
S
H
M
H
D
-----------------------------------------
V
G
V
V
H
R
D
L
K
P
E
N
L
L
-
F
T
D
----
L
E
--
I
K
I
I
D
F
G
F
A
R
-------
L
K
P
P
---------------------------
N
G
Y
D
E
S
C
D
L
W
S
L
G
V
I
L
Y
T
M
L
S
G
Q
V
P
F
Q
S
H
-------
D
R
S
L
T
C
-
T
S
A
V
E
I
M
K
K
I
K
K
G
D
F
S
F
E
G
E
A
W
K
N
V
S
Q
E
A
K
D
L
I
Q
G
L
L
T
V
D
P
N
K
R
L
K
M
S
G
L
R
Y
N
E
W
L
Q
DG
S
Q
L
S
S
N
P
L
M
T
P
D
I
L
G
S
S
G
A
A
V
H
T
C
V
----
K
A
T
F
H
A
F
N
K
Y
K
R
E
G
---------------------------------------------------
39
PsiBlast_CBE
59.34
31%
-97
- C1 -
2JAM
3
KCC1G_HUMAN
B:
[15-269]
----------------------------------------------------
E
V
L
G
S
G
A
F
S
E
V
F
L
V
K
Q
R
L
T
G
K
L
F
A
L
K
C
I
K
K
S
-----------
S
L
E
N
E
I
A
V
L
K
K
I
K
-
H
E
N
I
V
T
L
E
D
I
Y
E
S
T
T
H
Y
Y
L
V
M
Q
L
V
S
G
G
E
L
F
D
R
I
L
E
R
G
V
Y
T
E
K
D
A
S
L
V
I
Q
Q
V
L
S
A
V
K
Y
L
H
E
-----------------------------------------
N
G
I
V
H
R
D
L
K
P
E
N
L
L
-
Y
L
T
P
E
E
N
S
K
--
I
M
I
T
D
F
G
L
-
S
K
M
E
Q
N
G
I
--------
M
S
T
A
C
G
T
P
G
Y
V
A
P
E
V
L
-----
A
Q
K
P
Y
S
K
A
V
D
C
W
S
I
G
V
I
T
Y
I
L
L
C
G
Y
P
P
F
Y
E
E
T
---------------
E
S
K
L
F
E
K
I
K
E
G
Y
Y
E
F
E
S
P
F
W
D
D
I
S
E
S
A
K
D
F
I
C
H
L
L
E
K
D
P
N
E
R
Y
T
C
E
K
A
L
S
H
P
W
I
D
--
G
N
T
A
L
H
R
D
I
Y
P
S
V
S
L
Q
I
Q
K
N
F
A
K
-----------------------------------------------------------------------