@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : TAF1_HUMAN: (2015-10-20 )
MGPGCDLLLRTAATITAAAIMSDTDSDEDSAGGGPFSLAGFLFGNINGAGQLEGESVLDDECKKHLAGLGALGLGSLITELTANEELTGTDGALVNDEGWVRSTEDAVDYSDINEVAEDESRRYQQTMGSLQPLCHSDYDEDDYDADCEDIDCKLMPPPPPPPGPMKKDKDQDSITGEKVDFSSSSDSESEMGPQEATQAESEDGKLTLPLAGIMQHDATKLLPSVTELFPEFRPGKVLRFLRLFGPGKNVPSVWRSARRKRKKKHRELIQEEQIQEVECSVESEVSQKSLWNYDYAPPPPPEQCLSDDEITMMAPVESKFSQSTGDIDKVTDTKPRVAEWRYGPARLWYDMLGVPEDGSGFDYGFKLRKTEHEPVIKSRMIEEFRKLEENNGTDLLADENFLMVTQLHWEDDIIWDGEDVKHKGTKPQRASLAGWLPSSMTRNAMAYNVQQGFAATLDDDKPWYSIFPIDNEDLVYGRWEDNIIWDAQAMPRLLEPPVLTLDPNDENLILEIPDEKEEATSNSPSKESKKESSLKKSRILLGKTGVIKEEPQQNMSQPEVKDPWNLSNDEYYYPKQQGLRGTFGGNIIQHSIPAVELRQPFFPTHMGPIKLRQFHRPPLKKYSFGALSQPGPHSVQPLLKHIKKKAKMREQERQASGGGEMFFMRTPQDLTGKDGDLILAEYSEENGPLMMQVGMATKIKNYYKRKPGKDPGAPDCKYGETVYCHTSPFLGSLHPGQLLQAFENNLFRAPIYLHKMPETDFLIIRTRQGYYIRELVDIFVVGQQCPLFEVPGPNSKRANTHIRDFLQVFIYRLFWKSKDRPRRIRMEDIKKAFPSHSESSIRKRLKLCADFKRTGMDSNWWVLKSDFRLPTEEEIRAMVSPEQCCAYYSMIAAEQRLKDAGYGEKSFFAPEEENEEDFQMKIDDEVRTAPWNTTRAFIAAMKGKCLLEVTGVADPTGCGEGFSYVKIPNKPTQQKDDKEPQPVKKTVTGTDADLRRLSLKNAKQLLRKFGVPEEEIKKLSRWEVIDVVRTMSTEQARSGEGPMSKFARGSRFSVAEHQERYKEECQRIFDLQNKVLSSTEVLSTDTDSSSAEDSDFEEMGKNIENMLQNKKTSSQLSREREEQERKELQRMLLAAGSAASGNNHRDDDTASVTSLNSSATGRCLKIYRTFRDEEGKEYVRCETVRKPAVIDAYVRIRTTKDEEFIRKFALFDEQHREEMRKERRRIQEQLRRLKRNQEKEKLKGPPEKKPKKMKERPDLKLKCGACGAIGHMRTNKFCPLYYQTNAPPSNPVAMTEEQEEELEKTVIHNDNEELIKVEGTKIVLGKQLIESADEVRRKSLVLKFPKQQLPPKKKRRVGTTVHCDYLNRPHKSIHRRRTDPMVTLSSILESIINDMRDLPNTYPFHTPVNAKVVKDYYKIITRPMDLQTLRENVRKRLYPSREEFREHLELIVKNSATYNGPKHSLTQISQSMLDLCDEKLKEKEDKLARLEKAINPLLDDDDQVAFSFILDNIVTQKMMAVPDSWPFHHPVNKKFVPDYYKVIVNPMDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPESQYTKTAQEIVNVCYQTLTEYDEHLTQLEKDICTAKEAALEEAELESLDPMTPGPYTPQPPDLYDTNTSLSMSRDASVFQDESNMSVLDIPSATPEKQVTQEGEDGDGDLADEEEGTVQQPQASVLYEDLLMSEGEDDEEDAGSDEEGDNPFSAIQLSESGSDSDVGSGGIRPKQPRMLQENTRMDMENEESMMSYEGDGGEASHGLEDSNISYGSYEEPDPKSNTQDTSFSSIGGYEVSEEEEDEEEEEQRSGPSVLSQVHLSEDEEDSEDFHSIAGDSDLDSDE
Atome Classification :
(4 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570.......580.......590.......600.......610.......620.......630.......640.......650.......660.......670.......680.......690.......700.......710.......720.......730.......740.......750.......760.......770.......780.......790.......800.......810.......820.......830.......840.......850.......860.......870.......880.......890.......900.......910.......920.......930.......940.......950.......960.......970.......980.......990.......1000......1010......1020......1030......1040......1050......1060......1070......1080......1090......1100......1110......1120......1130......1140......1150......1160......1170......1180......1190......1200......1210......1220......1230......1240......1250......1260......1270......1280......1290......1300......1310......1320......1330......1340......1350......1360......1370......1380......1390......1400......1410......1420......1430......1440......1450......1460......1470......1480......1490......1500......1510......1520......1530......1540......1550......1560......1570......1580......1590......1600......1610......1620......1630......1640......1650......1660......1670......1680......1690......1700......1710......1720......1730......1740......1750......1760......1770......1780......1790......1800......1810......1820......1830......1840......1850......1860......1870
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MGPG
C
D
L
L
L
R
T
A
A
T
I
T
A
A
A
IMSDTDSDEDSAGGG
P
F
S
L
A
G
F
L
FGNINGAGQLEGESV
L
D
D
E
C
K
K
H
L
A
GLG
A
L
G
L
G
S
L
I
T
E
L
TANEELTGTDG
A
L
VNDEGWVRSTEDAV
D
Y
S
D
I
N
E
V
A
E
D
E
S
R
R
Y
Q
Q
T
M
G
SL
Q
P
L
CHSDYDEDDYDADCEDIDCKLMPPPPPPPGPMKKDKDQDSITGE
K
V
DFSSSSDSESEMG
P
Q
E
ATQAESEDG
K
L
T
L
P
L
A
G
I
M
Q
H
D
A
T
K
L
L
P
S
V
T
E
LFPEFR
P
G
K
V
L
R
F
L
R
L
FGPGKN
V
P
S
V
W
R
S
A
R
R
K
R
K
K
K
H
R
E
L
I
Q
E
E
Q
I
Q
E
V
E
CS
V
E
S
EV
S
Q
K
SLWNYDYAPPP
P
P
E
QCLSDD
E
I
T
M
MAP
V
E
S
K
FSQSTGDIDKVTDTKPRVAEWRY
G
P
A
R
L
W
Y
D
M
LGVPEDGSGFDYG
F
K
LRKTEHE
P
V
I
K
S
R
M
I
E
E
F
R
K
L
E
ENNGTDLLADE
N
F
L
M
V
T
Q
L
HWEDD
I
I
WDGEDVKHKGTKPQ
R
A
S
L
A
GWLP
S
S
MTRN
A
M
A
YNVQQG
F
A
ATLDDDKP
W
Y
S
I
F
PIDNE
D
L
V
Y
G
RWED
N
I
I
W
D
A
Q
AM
P
R
LLEP
P
V
L
T
LDPND
E
N
L
I
L
EIPD
E
K
E
EATSNSPSK
E
S
K
K
E
S
S
L
K
KS
R
I
L
LGKTGVIKEE
P
Q
QNMSQPEVKDPWNLSNDEYYY
P
K
QQGLRGTFGG
N
I
I
Q
HSIP
A
V
E
LRQPFFPTHMG
P
I
K
L
R
Q
FHRPP
L
K
KYSFGALSQPGP
H
S
V
Q
P
L
L
K
H
I
K
K
K
A
K
M
R
E
Q
E
RQASGGG
E
M
F
F
M
RTPQDLTGKDG
D
L
I
L
A
EYSEENG
P
L
M
M
QVG
M
A
T
K
I
K
N
Y
Y
KRKPGKDPGAPDCKYG
E
T
V
Y
C
HTSPFLGSL
H
P
G
Q
L
L
Q
A
F
ENNLFRA
P
I
Y
L
HKMPET
D
F
L
I
I
R
TRQ
G
Y
Y
I
R
E
L
V
D
I
F
VVGQQCP
L
F
EVPGPNSKRA
N
T
H
I
R
D
F
L
Q
V
F
I
Y
R
L
F
WKSKDRPRRI
R
M
E
D
I
K
K
AFPSH
S
E
S
S
I
R
K
R
L
K
L
C
A
D
F
K
RTGMDSN
W
W
V
L
KSDFRLP
T
E
E
E
I
R
A
MV
S
P
E
Q
C
C
A
Y
Y
S
M
I
A
A
E
Q
R
L
K
DAGYGEKSFFAPEEENEED
F
Q
M
K
IDDEVRTAPW
N
T
T
R
A
F
I
A
A
MKG
K
C
L
L
E
V
TGVADPTGCGEG
F
S
Y
V
KIPNKPTQQKDDKEPQP
V
K
KTVTGT
D
A
D
L
R
R
L
S
L
K
N
A
K
Q
L
L
R
KFGV
P
E
E
E
I
K
K
L
S
R
W
E
V
I
D
V
V
R
TM
S
T
E
QARSGEG
P
M
S
K
FARGSRF
S
V
A
E
H
Q
E
R
Y
K
E
E
C
Q
R
I
F
D
L
Q
N
K
VLSS
T
E
V
L
STDTDSSSAEDS
D
F
E
E
M
G
K
N
I
E
N
M
L
Q
NKK
T
S
S
Q
L
S
R
E
R
E
E
Q
E
R
K
E
L
Q
R
M
L
L
AAGSAASGNNHRDDDTA
S
V
TSLNSSAT
G
R
C
L
K
I
Y
R
T
F
R
D
EEGK
E
Y
V
R
C
ETVRKP
A
V
I
D
A
Y
V
R
I
R
TT
K
D
E
E
F
I
R
K
F
ALF
D
E
Q
H
R
E
E
M
R
K
E
R
R
R
I
Q
E
Q
L
R
R
L
K
RN
Q
E
K
E
KLKGPPEKK
P
K
K
M
KERPD
L
K
L
KCGACGAIGHMRTNKF
C
P
L
Y
Y
QTNAPPSNPVAM
T
E
E
Q
E
E
E
L
E
K
T
V
IHNDNE
E
L
I
K
VEG
T
K
I
V
L
G
K
Q
L
I
E
S
A
D
E
V
R
R
K
S
L
V
L
KF
P
K
QQLP
P
K
K
KRRVG
T
T
V
H
C
D
YLNR
P
H
K
S
I
H
RRRTD
P
M
V
T
L
S
S
I
L
E
S
I
I
N
D
M
R
DLPNTYPFHTPV
N
A
K
V
V
K
D
Y
Y
K
I
ITRPM
D
L
Q
T
L
R
E
N
V
R
K
RLYP
S
R
E
E
F
R
E
H
L
E
L
I
V
KNSATYNGPK
H
S
L
T
Q
I
S
Q
S
M
L
D
L
C
D
E
K
L
K
E
K
E
D
K
L
A
R
L
E
K
A
I
N
PLLDDD
D
Q
V
A
F
S
F
I
L
D
N
I
V
T
Q
K
M
MAVPDSWPFHHPVNKKF
V
P
D
Y
Y
K
V
IVNPM
D
L
E
T
I
R
K
N
I
S
K
H
K
Y
Q
S
R
E
S
F
L
D
D
V
N
L
I
L
ANSVKYNG
P
E
S
Q
Y
T
K
T
A
Q
E
I
V
N
V
C
Y
Q
T
L
T
E
Y
D
E
H
L
T
Q
L
E
K
D
I
C
T
A
K
E
A
A
L
E
E
A
ELESLDPMTPGPYTPQPPDLYDTNTSLSMSRDA
S
V
FQDESN
M
S
V
L
DIPSATP
E
K
Q
VTQEGEDGDGDLADEEEGTVQQ
P
Q
A
S
V
L
Y
E
D
L
L
MSEGEDDEEDAGSDEEGDNP
F
S
A
I
Q
LSESGSDSDVGSGGIRPKQ
P
R
M
L
Q
E
NTRMDMENE
E
S
M
MSYEGDGGEASHGLEDSNISYGSYEEPDPKSNTQDTSFSSIGGYEVSEEEE
D
E
E
E
E
E
Q
RS
G
P
S
V
L
S
Q
VHLSEDEE
D
S
E
D
F
H
S
IAGDSDLDSDE
7
PsiBlast_PDB
57.09
100%
-3
- C5 -
3UV4
2
TAF1_HUMAN
A:
[24-145]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
D
D
Q
V
A
F
S
F
I
L
D
N
I
V
T
Q
K
M
M
A
V
P
D
S
W
P
F
H
H
P
V
N
K
K
F
V
P
D
Y
Y
K
V
I
V
N
P
M
D
L
E
T
I
R
K
N
I
S
K
H
K
Y
Q
S
R
E
S
F
L
D
D
V
N
L
I
L
A
N
S
V
K
Y
N
G
P
E
S
Q
Y
T
K
T
A
Q
E
I
V
N
V
C
Y
Q
T
L
T
E
Y
D
E
H
L
T
Q
L
E
K
D
I
C
T
A
K
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
56.25
100%
-6
- C5 -
3UV4
2
B:
[24-145]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
D
D
Q
V
A
F
S
F
I
L
D
N
I
V
T
Q
K
M
M
A
V
P
D
S
W
P
F
H
H
P
V
N
K
K
F
V
P
D
Y
Y
K
V
I
V
N
P
M
D
L
E
T
I
R
K
N
I
S
K
H
K
Y
Q
S
R
E
S
F
L
D
D
V
N
L
I
L
A
N
S
V
K
Y
N
G
P
E
S
Q
Y
T
K
T
A
Q
E
I
V
N
V
C
Y
Q
T
L
T
E
Y
D
E
H
L
T
Q
L
E
K
D
I
C
T
A
K
E
A
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
49.15
32%
30
- C5 -
3NXB
1
CECR2_HUMAN
A:
[15-115]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
D
D
F
T
A
M
Y
K
V
L
D
V
V
K
A
H
K
-----
D
S
W
P
F
L
E
P
V
D
E
S
Y
A
P
N
Y
Y
Q
I
I
K
A
P
M
D
I
S
S
M
E
K
K
L
N
G
G
L
Y
C
T
K
E
E
F
V
N
D
M
K
T
M
F
R
N
C
R
K
Y
N
G
E
S
S
E
Y
T
K
M
S
D
N
L
E
R
C
F
H
R
A
M
M
K
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
PsiBlast_CBE
47.97
32%
38
- C5 -
3NXB
2
B:
[16-115]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
D
F
T
A
M
Y
K
V
L
D
V
V
K
A
H
K
-----
D
S
W
P
F
L
E
P
V
D
E
S
Y
A
P
N
Y
Y
Q
I
I
K
A
P
M
D
I
S
S
M
E
K
K
L
N
G
G
L
Y
C
T
K
E
E
F
V
N
D
M
K
T
M
F
R
N
C
R
K
Y
N
G
E
S
S
E
Y
T
K
M
S
D
N
L
E
R
C
F
H
R
A
M
M
K
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------