@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : TRPM7_HUMAN: (2015-10-21 )
MSQKSWIESTLTKRECVYIIPSSKDPHRCLPGCQICQQLVRCFCGRLVKQHACFTASLAMKYSDVKLGDHFNQAIEEWSVEKHTEQSPTDAYGVINFQGGSHSYRAKYVRLSYDTKPEVILQLLLKEWQMELPKLVISVHGGMQKFELHPRIKQLLGKGLIKAAVTTGAWILTGGVNTGVAKHVGDALKEHASRSSRKICTIGIAPWGVIENRNDLVGRDVVAPYQTLLNPLSKLNVLNNLHSHFILVDDGTVGKYGAEVRLRRELEKTINQQRIHARIGQGVPVVALIFEGGPNVILTVLEYLQESPPVPVVVCEGTGRAADLLAYIHKQTEEGGNLPDAAEPDIISTIKKTFNFGQNEALHLFQTLMECMKRKELITVFHIGSDEHQDIDVAILTALLKGTNASAFDQLILTLAWDRVDIAKNHVFVYGQQWLVGSLEQAMLDALVMDRVAFVKLLIENGVSMHKFLTIPRLEELYNTKQGPTNPMLFHLVRDVKQGNLPPGYKITLIDIGLVIEYLMGGTYRCTYTRKRFRLIYNSLGGNNRRSGRNTSSSTPQLRKSHESFGNRADKKEKMRHNHFIKTAQPYRPKIDTVMEEGKKKRTKDEIVDIDDPETKRFPYPLNELLIWACLMKRQVMARFLWQHGEESMAKALVACKIYRSMAYEAKQSDLVDDTSEELKQYSNDFGQLAVELLEQSFRQDETMAMKLLTYELKNWSNSTCLKLAVSSRLRPFVAHTCTQMLLSDMWMGRLNMRKNSWYKVILSILVPPAILLLEYKTKAEMSHIPQSQDAHQMTMDDSENNFQNITEEIPMEVFKEVRILDSNEGKNEMEIQMKSKKLPITRKFYAFYHAPIVKFWFNTLAYLGFLMLYTFVVLVQMEQLPSVQEWIVIAYIFTYAIEKVREIFMSEAGKVNQKIKVWFSDYFNISDTIAIISFFIGFGLRFGAKWNFANAYDNHVFVAGRLIYCLNIIFWYVRLLDFLAVNQQAGPYVMMIGKMVANMFYIVVIMALVLLSFGVPRKAILYPHEAPSWTLAKDIVFHPYWMIFGEVYAYEIDVCANDSVIPQICGPGTWLTPFLQAVYLFVQYIIMVNLLIAFFNNVYLQVKAISNIVWKYQRYHFIMAYHEKPVLPPPLIILSHIVSLFCCICKRRKKDKTSDGPKLFLTEEDQKKLHDFEEQCVEMYFNEKDDKFHSGSEERIRVTFERVEQMCIQIKEVGDRVNYIKRSLQSLDSQIGHLQDLSALTVDTLKTLTAQKASEASKVHNEITRELSISKHLAQNLIDDGPVRPSVWKKHGVVNTLSSSLPQGDLESNNPFHCNILMKDDKDPQCNIFGQDLPAVPQRKEFNFPEAGSSSGALFPSAVSPPELRQRLHGVELLKIFNKNQKLGSSSTSIPHLSSPPTKFFVSTPSQPSCKSHLETGTKDQETVCSKATEGDNTEFGAFVGHRDSMDLQRFKETSNKIKILSNNNTSENTLKRVSSLAGFTDCHRTSIPVHSKQAEKISRRPSTEDTHEVDSKAALIPDWLQDRPSNREMPSEEGTLNGLTSPFKPAMDTNYYYSAVERNNLMRLSQSIPFTPVPPRGEPVTVYRLEESSPNILNNSMSSWSQLGLCAKIEFLSKEEMGGGLRRAVKVQCTWSEHDILKSGHLYIIKSFLPEVVNTWSSIYKEDTVLHLCLREIQQQRAAQKLTFAFNQMKPKSIPYSPRFLEVFLLYCHSAGQWFAVEECMTGEFRKYNNNNGDEIIPTNTLEEIMLAFSHWTYEYTRGELLVLDLQGVGENLTDPSVIKAEEKRSCDMVFGPANLGEDAIKNFRAKHHCNSCCRKLKLPDLKRNDYTPDKIIFPQDEPSDLNLQPGNSTKESESTNSVRLML
Atome Classification :
(6 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570.......580.......590.......600.......610.......620.......630.......640.......650.......660.......670.......680.......690.......700.......710.......720.......730.......740.......750.......760.......770.......780.......790.......800.......810.......820.......830.......840.......850.......860.......870.......880.......890.......900.......910.......920.......930.......940.......950.......960.......970.......980.......990.......1000......1010......1020......1030......1040......1050......1060......1070......1080......1090......1100......1110......1120......1130......1140......1150......1160......1170......1180......1190......1200......1210......1220......1230......1240......1250......1260......1270......1280......1290......1300......1310......1320......1330......1340......1350......1360......1370......1380......1390......1400......1410......1420......1430......1440......1450......1460......1470......1480......1490......1500......1510......1520......1530......1540......1550......1560......1570......1580......1590......1600......1610......1620......1630......1640......1650......-1660......1670......1680......1690......1700......1710--.......--..1720......1730......1740......1750......1760......1770......1780......1790......1800......1810......1820......1830......1840......1850......1860..
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MS
Q
K
S
W
I
E
S
TLTKR
E
C
V
Y
I
IPSSKDPHRCL
P
G
C
Q
I
C
Q
Q
L
V
R
C
F
C
G
R
L
V
K
Q
HA
C
F
T
A
S
L
A
M
K
YSDVK
L
G
D
H
F
N
Q
A
I
E
E
WSVEKHTEQSPTDA
Y
G
V
I
N
FQGGSH
S
Y
R
A
K
Y
V
R
L
SYDT
K
P
E
V
I
L
Q
L
L
L
K
E
W
Q
M
E
L
P
K
L
V
I
S
VHGGMQKFEL
H
P
R
I
K
Q
L
L
G
K
G
L
I
K
A
AVTT
G
A
W
I
L
TGGVNT
G
V
A
K
H
V
G
D
A
L
K
E
H
A
SRSSR
K
I
C
T
I
GIAPWGVIENRNDLVGR
D
V
V
A
P
Y
Q
T
L
L
N
P
L
S
K
L
N
V
L
N
NLHS
H
F
I
L
VDDGTVGKY
G
A
E
V
R
L
R
R
E
L
E
K
T
I
N
Q
Q
R
I
H
A
R
IGQGV
P
V
V
A
L
I
FEGG
P
N
V
I
L
T
V
L
E
Y
L
QESPP
V
P
V
V
V
CEGTG
R
A
A
D
L
L
A
Y
I
H
K
Q
T
EEGGNLPDAAE
P
D
I
I
S
T
I
K
K
T
FNFGQN
E
A
L
H
L
F
Q
T
L
M
E
C
M
K
RK
E
L
I
T
V
F
H
IGSDEHQ
D
I
D
V
A
I
L
T
A
L
L
KGT
N
A
S
A
F
D
Q
L
I
L
T
L
AWDRVDIAKN
H
V
F
V
Y
G
Q
Q
W
L
V
G
S
L
E
Q
A
M
L
D
A
L
V
M
D
R
V
A
F
V
K
L
L
I
ENGV
S
M
H
K
F
LT
I
P
R
L
E
E
L
YNTKQGPT
N
P
M
L
F
H
L
V
R
D
V
K
QGNLPPG
Y
K
I
T
L
I
D
I
G
L
V
I
E
Y
L
MGG
T
Y
R
C
T
Y
T
R
K
R
F
R
L
I
Y
N
SLGGNNRRSGRNTSSS
T
P
Q
L
R
K
S
H
E
S
FGNR
A
D
K
K
E
K
M
R
HNHFIKTAQPYRP
K
I
D
T
V
M
E
EGKKKRTKDEIVDIDDPETKRFPY
P
L
N
E
L
L
I
W
A
C
L
M
K
R
Q
V
M
A
R
F
L
W
QH
G
E
E
S
M
A
K
A
L
V
A
C
K
I
Y
R
S
M
A
Y
EAKQSDLVDD
T
S
E
E
L
K
Q
Y
S
N
D
F
G
Q
L
A
V
E
L
L
E
Q
S
FRQ
D
E
T
M
A
M
K
L
L
T
Y
ELKNWSN
S
T
C
L
K
L
A
V
S
SRL
R
P
F
V
A
H
T
C
T
Q
M
L
L
S
D
M
W
M
G
RLNMRK
N
S
W
Y
K
V
I
L
S
I
LVPP
A
I
L
L
L
E
YKTK
A
E
M
SHIPQSQDAHQMTMDDSEN
N
F
Q
N
I
T
E
EI
P
M
E
V
F
K
E
V
R
ILDSNEGKN
E
M
E
I
Q
M
KSKKLP
I
T
R
K
F
Y
A
F
Y
H
A
P
I
V
K
F
W
F
N
T
L
A
Y
L
G
F
L
M
L
Y
T
F
V
V
L
V
Q
M
E
QLP
S
V
Q
E
W
I
V
I
A
Y
I
F
T
Y
A
I
E
K
V
R
E
I
F
M
S
E
AGKVN
Q
K
I
K
V
W
F
S
DYFNI
S
D
T
I
A
I
I
S
F
F
I
G
F
G
LRFGAKWNFANAYD
N
H
V
F
V
A
G
R
L
I
Y
C
L
N
I
I
F
W
Y
V
R
L
L
D
F
L
A
VNQQAGP
Y
V
M
M
I
G
K
M
V
A
N
M
F
Y
I
V
V
I
M
A
L
V
L
L
SFGVPR
K
A
I
LYPHEAPS
W
T
L
A
K
D
I
V
F
H
P
Y
W
M
I
F
G
E
V
Y
A
Y
E
I
D
VCANDSVIPQICGPG
T
W
L
T
P
F
L
Q
A
V
Y
L
F
V
Q
Y
I
I
M
V
N
L
L
I
A
F
FNN
V
Y
L
Q
V
K
A
I
S
N
I
V
W
K
Y
Q
R
Y
H
F
I
M
A
YHEKPVLP
P
P
L
I
I
L
S
H
I
V
S
L
F
C
C
I
C
K
RRKKDKTSDG
P
K
L
F
LT
E
E
D
Q
K
K
L
H
D
F
E
E
Q
C
V
E
M
Y
FNEKDDKFHSGS
E
E
R
I
R
V
T
F
E
R
V
E
Q
M
C
I
Q
I
K
E
VG
D
R
V
N
Y
I
K
R
S
L
Q
S
L
D
S
Q
IG
H
L
Q
D
L
S
A
L
T
V
D
T
L
K
T
L
T
A
Q
K
A
S
E
A
S
K
V
H
N
E
I
T
R
E
L
S
I
S
K
H
L
A
Q
N
LIDDGPVR
P
S
V
W
K
KHG
V
V
N
T
L
S
SSLPQGDLESNN
P
F
H
C
N
I
L
M
KDDKDPQCNIFGQDLPAVPQRKEFNFPEAGSSSGALFPSAVS
P
P
E
L
R
Q
R
L
H
G
V
E
L
L
K
I
FNKNQKLGSSSTSIPHLSSPP
T
K
F
F
VSTPSQP
S
C
K
S
H
L
ETGTK
D
Q
E
T
V
C
SKATEGDNTE
F
G
A
F
VGHRDSM
D
L
Q
R
F
K
ETSN
K
I
K
I
L
SNNNT
S
E
N
T
L
K
R
V
S
S
LAGFTDCHRTSIPV
H
S
K
Q
A
E
K
I
SRRPSTE
D
T
H
EVDSKAALI
P
D
W
L
QDRPSNREMPSEEGTLNGLTSPFKPAMDTN
Y
Y
Y
S
AVERN
N
L
M
R
L
S
QSIPFTPVPPRGE
P
V
T
V
Y
R
LEESSP
N
I
L
N
N
S
M
S
S
W
S
QLG
L
C
A
K
I
E
F
L
S
K
E
E
MGGGL
R
R
A
V
K
V
Q
C
TWSEH
D
I
LKSG
H
L
Y
I
I
K
S
F
L
P
E
V
V
N
T
W
S
-
S
I
Y
KE
D
T
V
L
H
L
C
L
R
E
I
Q
Q
Q
R
A
A
Q
K
L
T
F
A
F
NQMKPKSIPYS
P
R
F
L
E
V
F
L
L
Y
C-----HSAG
Q
W
F
--
A
V
E
E
CMTG
E
F
RKYNNNNG
D
E
IIP
T
N
T
L
E
E
I
M
L
A
F
S
H
W
T
Y
E
YTRG
E
L
L
V
L
DLQGVGENLTDP
S
V
I
K
A
E
EKRSC
D
M
V
FGPANL
G
E
D
A
I
K
N
F
R
A
K
H
H
C
N
S
C
C
R
KLKLPDLKRNDYTPD
K
I
IFPQDEPSDLNLQPGNSTKESEST
N
S
V
R
L
ML
19
PsiBlast_CBE
99.76
98%
-58
- C3 -
1IA9
2
B:
[1-280]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
N
Y
Y
Y
S
A
V
E
R
N
N
L
M
R
L
S
Q
S
I
P
F
V
P
V
P
P
R
G
E
P
V
T
V
Y
R
L
E
E
S
S
P
S
I
L
N
N
S
M
S
S
W
S
Q
L
G
L
C
A
K
I
E
F
L
S
K
E
E
M
G
G
G
L
R
R
A
V
K
V
L
C
T
W
S
E
H
D
I
L
K
S
G
H
L
Y
I
I
K
S
F
L
P
E
V
I
N
T
W
S
-
S
I
Y
K
E
D
T
V
L
H
L
C
L
R
E
I
Q
Q
Q
R
A
A
Q
K
L
T
F
A
F
N
Q
M
K
P
K
S
I
P
Y
S
P
R
F
L
E
V
F
L
L
Y
C
-----
H
S
A
G
Q
W
F
--
A
V
E
E
C
M
T
G
E
F
R
K
Y
N
N
N
N
G
D
E
I
I
P
T
N
T
L
E
E
I
M
L
A
F
S
H
W
T
Y
E
Y
T
R
G
E
L
L
V
L
D
L
Q
G
V
G
E
N
L
T
D
P
S
V
I
K
A
E
E
K
R
S
C
D
M
V
F
G
P
A
N
L
G
E
D
A
I
K
N
F
R
A
K
H
H
C
N
S
C
C
R
K
L
K
L
P
D
L
K
R
N
D
Y
T
-----------------------------------
18
PsiBlast_CBE
99.44
98%
-59
- C3 -
1IAH
2
B:
[1-280]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
N
Y
Y
Y
S
A
V
E
R
N
N
L
M
R
L
S
Q
S
I
P
F
V
P
V
P
P
R
G
E
P
V
T
V
Y
R
L
E
E
S
S
P
S
I
L
N
N
S
M
S
S
W
S
Q
L
G
L
C
A
K
I
E
F
L
S
K
E
E
M
G
G
G
L
R
R
A
V
K
V
L
C
T
W
S
E
H
D
I
L
K
S
G
H
L
Y
I
I
K
S
F
L
P
E
V
I
N
T
W
S
-
S
I
Y
K
E
D
T
V
L
H
L
C
L
R
E
I
Q
Q
Q
R
A
A
Q
K
L
T
F
A
F
N
Q
M
K
P
K
S
I
P
Y
S
P
R
F
L
E
V
F
L
L
Y
C
-----
H
S
A
G
Q
W
F
--
A
V
E
E
C
M
T
G
E
F
R
K
Y
N
N
N
N
G
D
E
I
I
P
T
N
T
L
E
E
I
M
L
A
F
S
H
W
T
Y
E
Y
T
R
G
E
L
L
V
L
D
L
Q
G
V
G
E
N
L
T
D
P
S
V
I
K
A
E
E
K
R
S
C
D
M
V
F
G
P
A
N
L
G
E
D
A
I
K
N
F
R
A
K
H
H
C
N
S
C
C
R
K
L
K
L
P
D
L
K
R
N
D
Y
T
-----------------------------------
1
PsiBlast_PDB
97.74
98%
-59
- C3 -
1IA9
2
TRPM7_MOUSE
A:
[3-280]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
Y
Y
S
A
V
E
R
N
N
L
M
R
L
S
Q
S
I
P
F
V
P
V
P
P
R
G
E
P
V
T
V
Y
R
L
E
E
S
S
P
S
I
L
N
N
S
M
S
S
W
S
Q
L
G
L
C
A
K
I
E
F
L
S
K
--
M
G
G
G
L
R
R
A
V
K
V
L
C
T
W
S
E
H
D
I
L
K
S
G
H
L
Y
I
I
K
S
F
L
P
E
V
I
N
T
W
S
-
S
I
Y
K
E
D
T
V
L
H
L
C
L
R
E
I
Q
Q
Q
R
A
A
Q
K
L
T
F
A
F
N
Q
M
K
P
K
S
I
P
Y
S
P
R
F
L
E
V
F
L
L
Y
C
-----
H
S
A
G
Q
W
F
--
A
V
E
E
C
M
T
G
E
F
R
K
Y
N
N
N
N
G
D
E
I
I
P
T
N
T
L
E
E
I
M
L
A
F
S
H
W
T
Y
E
Y
T
R
G
E
L
L
V
L
D
L
Q
G
V
G
E
N
L
T
D
P
S
V
I
K
A
E
E
K
R
S
C
D
M
V
F
G
P
A
N
L
G
E
D
A
I
K
N
F
R
A
K
H
H
C
N
S
C
C
R
K
L
K
L
P
D
L
K
R
N
D
Y
T
-----------------------------------
20
Fugue
97.40
97%
-57
- C3 -
1IA9
2
TRPM7_MOUSE
A:
[3-280]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
Y
Y
S
A
V
E
R
N
N
L
M
R
L
S
Q
S
I
P
F
V
P
V
P
P
R
G
E
P
V
T
V
Y
R
L
E
E
S
S
P
S
I
L
N
N
S
M
S
S
W
S
Q
L
G
L
C
A
K
I
E
F
L
S
K
M
G
--
G
G
L
R
R
A
V
K
V
L
C
T
W
S
E
H
D
I
L
K
S
G
H
L
Y
I
I
K
S
F
L
P
E
V
I
N
T
W
S
-
S
I
Y
K
E
D
T
V
L
H
L
C
L
R
E
I
Q
Q
Q
R
A
A
Q
K
L
T
F
A
F
N
Q
M
K
P
K
S
I
P
Y
S
P
R
F
L
E
V
F
L
L
Y
C
-----
H
S
A
G
Q
W
F
--
A
V
E
E
C
M
T
G
E
F
R
K
Y
N
N
N
N
G
D
E
I
I
P
T
N
T
L
E
E
I
M
L
A
F
S
H
W
T
Y
E
Y
T
R
G
E
L
L
V
L
D
L
Q
G
V
G
E
N
L
T
D
P
S
V
I
K
A
E
E
K
R
S
C
D
M
V
F
G
P
A
N
L
G
E
D
A
I
K
N
F
R
A
K
H
H
C
N
S
C
C
R
K
L
K
L
P
D
L
K
R
N
D
Y
T
-----------------------------------
2
PsiBlast_PDB
97.24
98%
-58
- C3 -
1IAH
2
TRPM7_MOUSE
A:
[3-280]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
Y
Y
S
A
V
E
R
N
N
L
M
R
L
S
Q
S
I
P
F
V
P
V
P
P
R
G
E
P
V
T
V
Y
R
L
E
E
S
S
P
S
I
L
N
N
S
M
S
S
W
S
Q
L
G
L
C
A
K
I
E
F
L
S
K
--
M
G
G
G
L
R
R
A
V
K
V
L
C
T
W
S
E
H
D
I
L
K
S
G
H
L
Y
I
I
K
S
F
L
P
E
V
I
N
T
W
S
-
S
I
Y
K
E
D
T
V
L
H
L
C
L
R
E
I
Q
Q
Q
R
A
A
Q
K
L
T
F
A
F
N
Q
M
K
P
K
S
I
P
Y
S
P
R
F
L
E
V
F
L
L
Y
C
-----
H
S
A
G
Q
W
F
--
A
V
E
E
C
M
T
G
E
F
R
K
Y
N
N
N
N
G
D
E
I
I
P
T
N
T
L
E
E
I
M
L
A
F
S
H
W
T
Y
E
Y
T
R
G
E
L
L
V
L
D
L
Q
G
V
G
E
N
L
T
D
P
S
V
I
K
A
E
E
K
R
S
C
D
M
V
F
G
P
A
N
L
G
E
D
A
I
K
N
F
R
A
K
H
H
C
N
S
C
C
R
K
L
K
L
P
D
L
K
R
N
D
Y
T
-----------------------------------
9
PsiBlast_PDB
53.69
30%
22
- C3 -
3PDT
1
A:
[102-271]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
K
N
G
T
K
F
V
L
K
L
Y
K
K
E
--
Q
Q
A
S
R
E
L
Y
F
E
D
V
K
M
Q
M
V
C
R
D
W
G
N
K
---------
F
N
Q
K
K
P
---
P
K
K
I
E
F
L
M
S
W
V
V
E
L
IDRSP
S
S
N
G
Q
P
I
L
C
S
I
E
P
L
L
V
G
E
F
K
K
N
N
S
N
Y
G
A
V
L
T
N
R
S
T
P
Q
----
A
F
S
H
F
T
Y
E
L
S
N
K
Q
M
I
V
V
D
I
Q
G
V
D
D
L
Y
T
D
P
Q
I
H
T
P
D
G
K
G
-----
F
G
L
G
N
L
G
K
A
G
I
N
K
F
I
T
T
H
K
C
N
A
V
C
A
L
L
D
L
D
V
K
L
----------------------------------------