@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : H_NR1F3_RORg: (2015-05-07 )
MDRAPQRQHRASRELLAAKKTHTSQIEVIPCKICGDKSSGIHYGVITCEGCKGFFRRSQRCNAAYSCTRQQNCPIDRTSRNRCQHCRLQKCLALGMSRDAVKFGRMSKKQRDSLHAEVQKQLQQRQQQQQEPVVKTPPAGAQGADTLTYTLGLPDGQLPLGSSPDLPEASACPPGLLKASGSGPSYSNNLAKAGLNGASCHLEYSPERGKAEGRESFYSTGSQLTPDRCGLRFEEHRHPGLGELGQGPDSYGSPSFRSTPEAPYASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLCKTHRQSILAKLPPKGKLRSLCSQHVERLQIFQHLHPIVVQAAFPPLYKELFSTETESPVGLSK
Atome Classification :
(14 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510......
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MDRA
P
Q
R
Q
H
R
A
S
R
E
L
L
A
AKKTHT
S
Q
I
E
V
I
P
C
K
ICGDKSSG
I
H
Y
G
V
I
T
CE
G
C
K
G
F
F
R
R
S
Q
RC
N
A
A
YSCTRQQNCPIDRTSR
N
R
C
Q
H
C
R
L
Q
K
C
L
A
LGMS
R
D
A
V
K
F
G
R
M
S
K
K
Q
R
D
S
L
H
A
E
V
Q
K
Q
L
Q
Q
R
Q
Q
Q
Q
QEP
V
V
KTPPAGAQGA
D
T
L
T
Y
T
LGLPDGQLPLGSSPDLPEASACPPG
L
L
KASGSGPSYSN
N
L
A
KAGLNGA
S
C
H
L
E
YSPERGKAE
G
R
E
S
F
Y
STGSQL
T
P
D
R
CGL
R
F
E
EHRHPGLGELGQGPDSYGSPSFRSTPEAP
Y
A
S
L
T
E
I
E
H
L
V
Q
S
V
C
K
S
Y
R
E
T
C
Q
L
R
L
E
D
L
L
R
Q
R
S
NIF
S
R
E
E
VT
G
Y
Q
R
K
S
M
W
E
M
W
E
R
C
A
H
H
L
T
E
A
I
Q
Y
V
V
E
F
A
K
R
L
S
G
F
M
E
L
CQND
Q
I
V
L
L
KAG
A
M
E
V
V
L
V
R
M
C
R
A
YNADN
R
T
V
F
F
EGKY
G
G
M
E
L
F
R
AL
G
C
S
E
L
I
S
S
I
F
D
FSHSLSALHFSE
D
E
I
A
L
Y
T
A
L
V
L
I
NAHRPG
L
Q
E
K
R
K
V
E
Q
L
Q
Y
N
L
E
L
A
F
H
H
H
L
C
K
T
H
R
Q
S
I
L
A
KLPPK
G
K
L
R
S
L
C
S
Q
H
V
E
R
L
Q
I
F
Q
H
L
H
P
I
V
V
QAAF
P
P
L
Y
K
E
L
FSTETESPVGLSK
6
PsiBlast_PDB
93.46
100%
-144
- C3 -
3KYT
1
A:
[1-243]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
S
L
T
E
I
E
H
L
V
Q
S
V
C
K
S
Y
R
E
T
C
Q
L
R
L
E
D
L
L
R
Q
R
S
N
I
F
S
R
E
E
V
T
G
Y
Q
R
K
S
M
W
E
M
W
E
R
C
A
H
H
L
T
E
A
I
Q
Y
V
V
E
F
A
K
R
L
S
G
F
M
E
L
C
Q
N
D
Q
I
V
L
L
K
A
G
A
M
E
V
V
L
V
R
M
C
R
A
Y
N
A
D
N
R
T
V
F
F
E
G
K
Y
G
G
M
E
L
F
R
A
L
G
C
S
E
L
I
S
S
I
F
D
F
S
H
S
L
S
A
L
H
F
S
E
D
E
I
A
L
Y
T
A
L
V
L
I
N
A
H
R
P
G
L
Q
E
K
R
K
V
E
Q
L
Q
Y
N
L
E
L
A
F
H
H
H
L
C
K
T
H
R
Q
S
I
L
A
K
L
P
P
K
G
K
L
R
S
L
C
S
Q
H
V
E
R
L
Q
I
F
Q
H
L
H
P
I
V
V
Q
A
A
F
P
P
L
Y
K
E
L
F
S
-----------
25
PsiBlast_CBE
93.37
100%
-145
- C3 -
4WLB
2
?
B:
[17-262]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
P
Y
A
S
L
T
E
I
E
H
L
V
Q
S
V
C
K
S
Y
R
E
T
C
Q
L
R
L
E
D
L
L
R
Q
R
S
N
I
F
S
R
E
E
V
T
G
Y
Q
R
K
S
M
W
E
M
W
E
R
C
A
H
H
L
T
E
A
I
Q
Y
V
V
E
F
A
K
R
L
S
G
F
M
E
L
C
Q
N
D
Q
I
V
L
L
K
A
G
A
M
E
V
V
L
V
R
M
C
R
A
Y
N
A
D
N
R
T
V
F
F
E
G
K
Y
G
G
M
E
L
F
R
A
L
G
C
S
E
L
I
S
S
I
F
D
F
S
H
S
L
S
A
L
H
F
S
E
D
E
I
A
L
Y
T
A
L
V
L
I
N
A
H
R
P
G
L
Q
E
K
R
K
V
E
Q
L
Q
Y
N
L
E
L
A
F
H
H
H
L
C
K
T
H
R
Q
S
I
L
A
K
L
P
P
K
G
K
L
R
S
L
C
S
Q
H
V
E
R
L
Q
I
F
Q
H
L
H
P
I
V
V
Q
A
A
F
P
P
L
Y
K
E
L
F
S
-----------
5
PsiBlast_PDB
93.32
100%
-142
- C3 -
4WLB
3
?
A:
[17-262]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
P
Y
A
S
L
T
E
I
E
H
L
V
Q
S
V
C
K
S
Y
R
E
T
C
Q
L
R
L
E
D
L
L
R
Q
R
S
N
I
F
S
R
E
E
V
T
G
Y
Q
R
K
S
M
W
E
M
W
E
R
C
A
H
H
L
T
E
A
I
Q
Y
V
V
E
F
A
K
R
L
S
G
F
M
E
L
C
Q
N
D
Q
I
V
L
L
K
A
G
A
M
E
V
V
L
V
R
M
C
R
A
Y
N
A
D
N
R
T
V
F
F
E
G
K
Y
G
G
M
E
L
F
R
A
L
G
C
S
E
L
I
S
S
I
F
D
F
S
H
S
L
S
A
L
H
F
S
E
D
E
I
A
L
Y
T
A
L
V
L
I
N
A
H
R
P
G
L
Q
E
K
R
K
V
E
Q
L
Q
Y
N
L
E
L
A
F
H
H
H
L
C
K
T
H
R
Q
S
I
L
A
K
L
P
P
K
G
K
L
R
S
L
C
S
Q
H
V
E
R
L
Q
I
F
Q
H
L
H
P
I
V
V
Q
A
A
F
P
P
L
Y
K
E
L
F
S
-----------
21
PsiBlast_CBE
93.22
100%
-136
- C3 -
3L0L
1
B:
[1-248]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
E
A
P
Y
A
S
L
T
E
I
E
H
L
V
Q
S
V
C
K
S
Y
R
E
T
C
Q
L
R
L
E
D
L
L
R
Q
R
S
N
I
F
S
R
E
E
V
T
G
Y
Q
R
K
S
M
W
E
M
W
E
R
C
A
H
H
L
T
E
A
I
Q
Y
V
V
E
F
A
K
R
L
S
G
F
M
E
L
C
Q
N
D
Q
I
V
L
L
K
A
G
A
M
E
V
V
L
V
R
M
C
R
A
Y
N
A
D
N
R
T
V
F
F
E
G
K
Y
G
G
M
E
L
F
R
A
L
G
C
S
E
L
I
S
S
I
F
D
F
S
H
S
L
S
A
L
H
F
S
E
D
E
I
A
L
Y
T
A
L
V
L
I
N
A
H
R
P
G
L
Q
E
K
R
K
V
E
Q
L
Q
Y
N
L
E
L
A
F
H
H
H
L
C
K
T
H
R
Q
S
I
L
A
K
L
P
P
K
G
K
L
R
S
L
C
S
Q
H
V
E
R
L
Q
I
F
Q
H
L
H
P
I
V
V
Q
A
A
F
P
P
L
Y
K
E
L
F
S
-----------
2
PsiBlast_PDB
93.16
99%
-147
- C3 -
4NIE
3
RORG_HUMAN
A:
[17-261]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
A
S
L
T
E
I
E
H
L
V
Q
S
V
C
K
S
Y
R
E
T
C
Q
L
R
L
E
D
L
L
R
Q
R
S
N
I
F
S
R
E
E
V
T
G
Y
Q
R
K
S
M
W
E
M
W
E
R
C
A
H
H
L
T
E
A
I
Q
Y
V
V
E
F
A
K
R
L
S
G
F
M
E
L
C
Q
N
D
Q
I
V
L
L
K
A
G
A
M
E
V
V
L
V
R
M
C
R
A
Y
N
A
D
N
R
T
V
F
F
E
G
K
Y
G
G
M
E
L
F
R
A
L
G
C
S
E
L
I
S
S
I
F
D
F
S
H
S
L
S
A
L
H
F
S
E
D
E
I
A
L
Y
T
A
L
V
L
I
N
A
H
R
P
G
L
Q
E
K
R
K
V
E
Q
L
Q
Y
N
L
E
L
A
F
H
H
H
L
C
K
T
H
R
Q
S
I
L
A
K
L
P
P
K
G
K
L
R
S
L
C
S
Q
H
V
E
R
L
Q
I
F
Q
H
L
H
P
I
V
V
Q
A
A
F
P
P
L
Y
K
E
L
F
S
T
----------
1
PsiBlast_PDB
93.11
100%
-141
- C3 -
3L0L
1
RORG_HUMAN
A:
[2-248]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
A
P
Y
A
S
L
T
E
I
E
H
L
V
Q
S
V
C
K
S
Y
R
E
T
C
Q
L
R
L
E
D
L
L
R
Q
R
S
N
I
F
S
R
E
E
V
T
G
Y
Q
R
K
S
M
W
E
M
W
E
R
C
A
H
H
L
T
E
A
I
Q
Y
V
V
E
F
A
K
R
L
S
G
F
M
E
L
C
Q
N
D
Q
I
V
L
L
K
A
G
A
M
E
V
V
L
V
R
M
C
R
A
Y
N
A
D
N
R
T
V
F
F
E
G
K
Y
G
G
M
E
L
F
R
A
L
G
C
S
E
L
I
S
S
I
F
D
F
S
H
S
L
S
A
L
H
F
S
E
D
E
I
A
L
Y
T
A
L
V
L
I
N
A
H
R
P
G
L
Q
E
K
R
K
V
E
Q
L
Q
Y
N
L
E
L
A
F
H
H
H
L
C
K
T
H
R
Q
S
I
L
A
K
L
P
P
K
G
K
L
R
S
L
C
S
Q
H
V
E
R
L
Q
I
F
Q
H
L
H
P
I
V
V
Q
A
A
F
P
P
L
Y
K
E
L
F
S
-----------
22
PsiBlast_CBE
92.82
99%
-142
- C3 -
4NIE
3
B:
[17-261]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
A
S
L
T
E
I
E
H
L
V
Q
S
V
C
K
S
Y
R
E
T
C
Q
L
R
L
E
D
L
L
R
Q
R
S
N
I
F
S
R
E
E
V
T
G
Y
Q
R
K
S
M
W
E
M
W
E
R
C
A
H
H
L
T
E
A
I
Q
Y
V
V
E
F
A
K
R
L
S
G
F
M
E
L
C
Q
N
D
Q
I
V
L
L
K
A
G
A
M
E
V
V
L
V
R
M
C
R
A
Y
N
A
D
N
R
T
V
F
F
E
G
K
Y
G
G
M
E
L
F
R
A
L
G
C
S
E
L
I
S
S
I
F
D
F
S
H
S
L
S
A
L
H
F
S
E
D
E
I
A
L
Y
T
A
L
V
L
I
N
A
H
R
P
G
L
Q
E
K
R
K
V
E
Q
L
Q
Y
N
L
E
L
A
F
H
H
H
L
C
K
T
H
R
Q
S
I
L
A
K
L
P
P
K
G
K
L
R
S
L
C
S
Q
H
V
E
R
L
Q
I
F
Q
H
L
H
P
I
V
V
Q
A
A
F
P
P
L
Y
K
E
L
F
S
T
----------
7
PsiBlast_PDB
92.05
100%
-142
- C3 -
3L0J
1
A:
[1-243]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
S
L
T
E
I
E
H
L
V
Q
S
V
C
K
S
Y
R
E
T
C
Q
L
R
L
E
D
L
L
R
Q
R
S
N
I
F
S
R
E
E
V
T
G
Y
Q
R
K
S
M
W
E
M
W
E
R
C
A
H
H
L
T
E
A
I
Q
Y
V
V
E
F
A
K
R
L
S
G
F
M
E
L
C
Q
N
D
Q
I
V
L
L
K
A
G
A
M
E
V
V
L
V
R
M
C
R
A
Y
N
A
D
N
R
T
V
F
F
E
G
K
Y
G
G
M
E
L
F
R
A
L
G
C
S
E
L
I
S
S
I
F
D
F
S
H
S
L
S
A
L
H
F
S
E
D
E
I
A
L
Y
T
A
L
V
L
I
N
A
H
R
P
G
L
Q
E
K
R
K
V
E
Q
L
Q
Y
N
L
E
L
A
F
H
H
H
L
C
K
T
H
R
Q
S
I
L
A
K
L
P
P
K
G
K
L
R
S
L
C
S
Q
H
V
E
R
L
Q
I
F
Q
H
L
H
P
I
V
V
Q
A
A
F
P
P
L
Y
K
E
L
F
S
-----------
23
PsiBlast_CBE
90.80
100%
-135
- C3 -
4QM0
2
C:
[6-248]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
S
L
T
E
I
E
H
L
V
Q
S
V
C
K
S
Y
R
E
T
C
Q
L
R
L
E
D
L
L
R
Q
R
S
N
I
F
S
R
E
E
V
T
G
Y
Q
R
K
S
M
W
E
M
W
E
R
C
A
H
H
L
T
E
A
I
Q
Y
V
V
E
F
A
K
R
L
S
G
F
M
E
L
C
Q
N
D
Q
I
V
L
L
K
A
G
A
M
E
V
V
L
V
R
M
C
R
A
Y
N
A
D
N
R
T
V
F
F
E
G
K
Y
G
G
M
E
L
F
R
A
L
G
C
S
E
L
I
S
S
I
F
D
F
S
H
S
L
S
A
L
H
F
S
E
D
E
I
A
L
Y
T
A
L
V
L
I
N
A
H
R
P
G
L
Q
E
K
R
K
V
E
Q
L
Q
Y
N
L
E
L
A
F
H
H
H
L
C
K
T
H
R
Q
S
I
L
A
K
L
P
P
K
G
K
L
R
S
L
C
S
Q
H
V
E
R
L
Q
----------
Q
A
A
F
P
P
L
Y
K
E
L
F
S
G
N
S
--------
4
PsiBlast_PDB
89.36
100%
-136
- C3 -
4QM0
2
RORG_HUMAN
A:
[6-239]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
S
L
T
E
I
E
H
L
V
Q
S
V
C
K
S
Y
R
E
T
C
Q
L
R
L
E
D
L
L
R
Q
R
S
N
I
F
S
R
E
E
V
T
G
Y
Q
R
K
S
M
W
E
M
W
E
R
C
A
H
H
L
T
E
A
I
Q
Y
V
V
E
F
A
K
R
L
S
G
F
M
E
L
C
Q
N
D
Q
I
V
L
L
K
A
G
A
M
E
V
V
L
V
R
M
C
R
A
Y
N
A
D
N
R
T
V
F
F
E
G
K
Y
G
G
M
E
L
F
R
A
L
G
C
S
E
L
I
S
S
I
F
D
F
S
H
S
L
S
A
L
H
F
S
E
D
E
I
A
L
Y
T
A
L
V
L
I
N
A
H
R
P
G
L
Q
E
K
R
K
V
E
Q
L
Q
Y
N
L
E
L
A
F
H
H
H
L
C
K
T
H
R
Q
S
I
L
A
K
L
P
P
K
G
K
L
R
S
L
C
S
Q
H
V
E
R
L
Q
I
F
Q
H
L
H
P
I
V
V
Q
A
A
F
--------------------
24
PsiBlast_CBE
86.29
100%
-139
- C3 -
4NB6
1
B:
[7-228]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
L
T
E
I
E
H
L
V
Q
S
V
C
K
S
Y
R
E
T
C
Q
L
R
L
E
D
L
L
R
Q
R
S
N
I
F
S
R
E
E
V
T
G
Y
Q
R
K
S
M
W
E
M
W
E
R
C
A
H
H
L
T
E
A
I
Q
Y
V
V
E
F
A
K
R
L
S
G
F
M
E
L
C
Q
N
D
Q
I
V
L
L
K
A
G
A
M
E
V
V
L
V
R
M
C
R
A
Y
N
A
D
N
R
T
V
F
F
E
G
K
Y
G
G
M
E
L
F
R
A
L
G
C
S
E
L
I
S
S
I
F
D
F
S
H
S
L
S
A
L
H
F
S
E
D
E
I
A
L
Y
T
A
L
V
L
I
N
A
H
R
P
G
L
Q
E
K
R
K
V
E
Q
L
Q
Y
N
L
E
L
A
F
H
H
H
L
C
K
T
H
R
Q
S
I
L
A
K
L
P
P
K
G
K
L
R
S
L
C
S
Q
H
V
E
R
L
Q
I
F
Q
-------------------------------
3
PsiBlast_PDB
85.75
100%
-139
- C3 -
4NB6
1
RORG_HUMAN
A:
[7-227]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
L
T
E
I
E
H
L
V
Q
S
V
C
K
S
Y
R
E
T
C
Q
L
R
L
E
D
L
L
R
Q
R
S
N
I
F
S
R
E
E
V
T
G
Y
Q
R
K
S
M
W
E
M
W
E
R
C
A
H
H
L
T
E
A
I
Q
Y
V
V
E
F
A
K
R
L
S
G
F
M
E
L
C
Q
N
D
Q
I
V
L
L
K
A
G
A
M
E
V
V
L
V
R
M
C
R
A
Y
N
A
D
N
R
T
V
F
F
E
G
K
Y
G
G
M
E
L
F
R
A
L
G
C
S
E
L
I
S
S
I
F
D
F
S
H
S
L
S
A
L
H
F
S
E
D
E
I
A
L
Y
T
A
L
V
L
I
N
A
H
R
P
G
L
Q
E
K
R
K
V
E
Q
L
Q
Y
N
L
E
L
A
F
H
H
H
L
C
K
T
H
R
Q
S
I
L
A
K
L
P
P
K
G
K
L
R
S
L
C
S
Q
H
V
E
R
L
Q
I
F
--------------------------------
8
PsiBlast_PDB
84.03
100%
-136
- C3 -
3B0W
1
RORG_HUMAN
A:
[1-215]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
S
L
T
E
I
E
H
L
V
Q
S
V
C
K
S
Y
R
E
T
C
Q
L
R
L
E
D
L
L
R
Q
R
S
N
I
F
S
R
E
E
V
T
G
Y
Q
R
K
S
M
W
E
M
W
E
R
C
A
H
H
L
T
E
A
I
Q
Y
V
V
E
F
A
K
R
L
S
G
F
M
E
L
C
Q
N
D
Q
I
V
L
L
K
A
G
A
M
E
V
V
L
V
R
M
C
R
A
Y
N
A
D
N
R
T
V
F
F
E
G
K
Y
G
G
M
E
L
F
R
A
L
G
C
S
E
L
I
S
S
I
F
D
F
S
H
S
L
S
A
L
H
F
S
E
D
E
I
A
L
Y
T
A
L
V
L
I
N
A
H
R
P
G
L
Q
E
K
R
K
V
E
Q
L
Q
Y
N
L
E
L
A
F
H
H
H
L
C
K
T
H
R
Q
S
I
L
A
K
L
P
P
K
G
K
L
R
S
L
C
S
Q
H
---------------------------------------
26
PsiBlast_CBE
83.79
100%
-135
- C3 -
3B0W
1
B:
[1-217]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
S
L
T
E
I
E
H
L
V
Q
S
V
C
K
S
Y
R
E
T
C
Q
L
R
L
E
D
L
L
R
Q
R
S
N
I
F
S
R
E
E
V
T
G
Y
Q
R
K
S
M
W
E
M
W
E
R
C
A
H
H
L
T
E
A
I
Q
Y
V
V
E
F
A
K
R
L
S
G
F
M
E
L
C
Q
N
D
Q
I
V
L
L
K
A
G
A
M
E
V
V
L
V
R
M
C
R
A
Y
N
A
D
N
R
T
V
F
F
E
G
K
Y
G
G
M
E
L
F
R
A
L
G
C
S
E
L
I
S
S
I
F
D
F
S
H
S
L
S
A
L
H
F
S
E
D
E
I
A
L
Y
T
A
L
V
L
I
N
A
H
R
P
G
L
Q
E
K
R
K
V
E
Q
L
Q
Y
N
L
E
L
A
F
H
H
H
L
C
K
T
H
R
Q
S
I
L
A
K
L
P
P
K
G
K
L
R
S
L
C
S
Q
H
V
E
-------------------------------------