@TOME V2.3
(Nov 2016)

Ref. - - Doc.
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Alignment:

3D Common Core:

Structural Clustering:

Modeller Result :

Complexes Modeling
Templates Information:
Sequence & Result Tab:

Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : H_NR3A2_ESRb: (2016-04-07 )
MDIKNSPSSLNSPSSYNCSQSILPLEHGSIYIPSSYVDSHHEYPAMTFYSPAVMNYSIPSNVTNLEGGPGRQTTSPNVLWPTPGHLSPLVVHRQLSHLYAEPQKSPWCEARSLEHTLPVNRETLKRKVSGNRCASPVTGPGSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRLVRRQRSADEQLHCAGKAKRSGGHAPRVRELLLDALSPEQLVLTLLEAEPPHVLISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDADSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVVPVYDLLLEMLNAHVLRGCKSSITGSECSPAEDSKSKEGSQNPQSQ

Atome Classification :

(193 SA) .........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280...--.....290.......300.......310.......320.......330.......340.......350.----......360.......370.......380......-..390.......400.......410...-....-420......-.430.......440.......450.......460.......470.......480...---....490.......500.......510.......520.......530
(Atome) (Ident) (Tito) (Num) (Ligand) (Uniprot) MDIKNSPSSLNSPSSYNCSQSILPLEHGSIYIPSSYVDSHHEYPAMTFYSPAVMNYSIPSNVTNLEGGPGRQTTSPNVLWPTPGHLSPLVVHRQLSHLYAEPQKSPWCEARSLEHTLPVNRETLKRKVSGNRCASPVTGPGSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRLVRRQRSADEQLHCAGKAKRSGGHAPRVRELLLDALSPEQLVLTLLEAEPPHVL-ISR--PSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLL-ATTSRF-RELKLQHKEYLCVKAMILLNSSMYPLVT-ATQD-ADSSRKLAH-LLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNAHVLRGCKSSITGSECSPAEDSKSKEGSQNPQSQ
34 PsiBlast_CBE 93.87100%-156 - C4 -4J24 ESR2_HUMAN A:[2-238] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALSPEQLVLTLLEAEPPHVL-ISR--PSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLL-ATTSRF-RELKLQHKEYLCVKAMILLNSS--------------SSRKLAH-LLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNAH--------------------------------
58 PsiBlast_CBE 93.1299%-158 - C4 -3OLL ESR2_HUMAN A:[2-238] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALSPEQLVLTLLEAEPPHVL-ISR--PSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLL-ATTSRF-RELKLQHKEYLCVKAMILLNSSMYPLVT-AT---ADSSRKLAH-LLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNAH--------------------------------
214 HHSearch 93.05100%-158 - C4 -3OLL ESR2_HUMAN A:[3-238] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-ISR--PSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLL-ATTSRF-RELKLQHKEYLCVKAMILLNSSMYPLVT-AT---ADSSRKLAH-LLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNAH--------------------------------
32 PsiBlast_CBE 92.94100%-159 - C4 -4J24 ESR2_HUMAN C:[2-238] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALSPEQLVLTLLEAEPPHVL-ISR--PSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLL-ATTSRF-RELKLQHKEYLCVKAMILLNSS--------------SSRKLAH-LLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNAH--------------------------------
28 PsiBlast_CBE 92.41100%-159 - C4 -1U3R B:[3-241] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-ISR--PSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLL-ATTSRF-RELKLQHKEYLCVKAMILLNSS--------------SSRKLAH-LLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNAHVLR-----------------------------
57 PsiBlast_CBE 92.3499%-160 - C4 -3OLL B:[2-238] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALSPEQLVLTLLEAEPPHVL-ISR--PSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLL-ATTSRF-RELKLQHKEYLCVKAMILLNSSMYPLVT-AT----DSSRKLAH-LLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNAH--------------------------------
42 PsiBlast_CBE 92.21100%-160 - C4 -2YJD ESR2_HUMAN A:[3-237] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-ISR--PSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLL-ATTSRF-RELKLQHKEYLCVKAMILLNSS--------------SSRKLAH-LLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNA---------------------------------
31 PsiBlast_CBE 92.09100%-161 - C4 -4J24 D:[4-237] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVL-ISR--PSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLL-ATTSRF-RELKLQHKEYLCVKAMILLNS---------------SSRKLAH-LLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNA---------------------------------
41 PsiBlast_CBE 91.82100%-158 - C4 -2YJD B:[3-237] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-ISR--PSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLL-ATTSRF-RELKLQHKEYLCVKAMILLNSS--------------SSRKLAH-LLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNA---------------------------------
3 PsiBlast_PDB 91.82100%-158 - C4 -1QKM A:[6-246] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LDALSPEQLVLTLLEAEPPHVL-ISR--P------ASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLL-ATTSRF-RELKLQHKEYLCVKAMILLNSSMYPLV-------ADSSRKLAH-LLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNAHVL------------------------------
36 PsiBlast_CBE 91.81100%-158 - C4 -3OMQ ESR2_HUMAN A:[4-237] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVL-ISR--PSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLL-ATTSRF-RELKLQHKEYLCVKAMILLNSSMYPLVT-------DSSRKLAH-LLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNA---------------------------------
33 PsiBlast_CBE 91.73100%-157 - C4 -4J24 ESR2_HUMAN B:[1-238] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DALSPEQLVLTLLEAEPPHVL-ISR--PSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLL-ATTSRF-RELKLQHKEYLCVKAMILLNSSM------------DSSRKLAH-LLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNAH--------------------------------
47 PsiBlast_CBE 91.70100%-156 - C4 -1U3S B:[3-237] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-ISR--PSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLL-ATTSRF-RELKLQHKEYLCVKAMILLNSS--------------SSRKLAH-LLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNA---------------------------------
12 PsiBlast_PDB 91.52100%-160 - C4 -2GIU A:[1-241] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LDALSPEQLVLTLLEAEPPHVL-ISR--P------ASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKC-EGILEIFDMLL-ATTSRF-RELKLQHKEYLCVKAMILLNSSMYPLV-------ADSSRKLAH-LLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNM----VV---PVYDLLLEMLNAHVL------------------------------
19 PsiBlast_PDB 91.41100%-158 - C4 -3OLS ESR2_HUMAN A:[4-237] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVL-ISR--PSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLL-ATTSRF-RELKLQHKEYLCVKAMILLNSSMYPLVT-------DSSRKLAH-LLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNA---------------------------------
20 PsiBlast_PDB 91.22100%-156 - C4 -3OMO ESR2_HUMAN A:[4-237] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVL-ISR--PSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLL-ATTSRF-RELKLQHKEYLCVKAMILLNSSMYPLVT-------DSSRKLAH-LLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNA---------------------------------
11 PsiBlast_PDB 91.14100%-156 - C4 -1U3R ESR2_HUMAN A:[3-240] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-ISR--PSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLL-ATTSRF-RELKLQHKEYLCVKAMILLNSSM--------QD-ADSSRKLAH-LLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNAHVL------------------------------
37 PsiBlast_CBE 91.06100%-161 - C4 -3OMP B:[4-235] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVL-ISR--PSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLL-ATTSRF-RELKLQHKEYLCVKAMILLNSSMYPLVT-A---------KLAH-LLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEML-----------------------------------
38 PsiBlast_CBE 91.03100%-157 - C4 -3OMP ESR2_HUMAN A:[4-237] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVL-ISR--PSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLL-ATTSRF-RELKLQHKEYLCVKAMILLNSSMYPLVT-------DSSRKLAH-LLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNA---------------------------------
10 PsiBlast_PDB 91.03100%-156 - C4 -1U9E ESR2_HUMAN A:[3-237] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-ISR--PSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLL-ATTSRF-RELKLQHKEYLCVKAMILLNSS--------------SSRKLAH-LLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNA---------------------------------
18 PsiBlast_PDB 90.98100%-152 - C4 -1U3S ESR2_HUMAN A:[3-237] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-ISR--PSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLL-ATTSRF-RELKLQHKEYLCVKAMILLNSSMY----------ADSSRKLAH-LLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNA---------------------------------
40 PsiBlast_CBE 90.97100%-159 - C4 -3OLS B:[4-235] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVL-ISR--PSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLL-ATTSRF-RELKLQHKEYLCVKAMILLNSSMYPLVT-A---------KLAH-LLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEML-----------------------------------
35 PsiBlast_CBE 90.92100%-160 - C4 -3OMQ B:[4-235] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVL-ISR--PSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLL-ATTSRF-RELKLQHKEYLCVKAMILLNSSMYPLVT-A---------KLAH-LLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEML-----------------------------------
39 PsiBlast_CBE 90.88100%-161 - C4 -3OMO B:[4-235] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVL-ISR--PSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLL-ATTSRF-RELKLQHKEYLCVKAMILLNSSMYPLVT-A---------KLAH-LLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEML-----------------------------------
56 PsiBlast_CBE 90.8699%-162 - C4 -2YLY ESR2_HUMAN A:[2-237] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DALSPEQLVLTLLEAEPPHVL-I--------FTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLL-ATTSRF-RELKLQHKEYLCVKAMILLNSS--------------SSRKLAH-LLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNA---------------------------------
15 PsiBlast_PDB 90.83100%-157 - C4 -1X7B ESR2_HUMAN A:[3-240] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-ISR--PSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLL-ATTSRF-RELKLQHKEYLCVKAMILLNSSM------------DSSRKLAH-LLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNAHVL------------------------------
30 PsiBlast_CBE 90.80100%-155 - C4 -4J26 ESR2_HUMAN A:[1-238] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DALSPEQLVLTLLEAEPPHVL-ISR--PSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLL-ATTSRF-RELKLQHKEYLCVKAMILLNSS------------ADSSRKLAH-LLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNAH--------------------------------
45 PsiBlast_CBE 90.34100%-155 - C4 -1X78 B:[3-240] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-ISR--PSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLL-ATTSRF-RELKLQHKEYLCVKAMILLNSSM------------DSSRKLAH-LLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNAHVL------------------------------
2 PsiBlast_PDB 90.30100%-159 - C4 -1YYE ESR2_HUMAN A:[1-238] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-ISR--PSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLL-ATTSRF-RELKLQHKEYLCVKAMILLNSSM------------DSSRKLAH-LLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNAHVL------------------------------
52 PsiBlast_CBE 90.27100%-157 - C4 -2NV7 ESR2_HUMAN A:[1-238] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-ISR--PSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLL-ATTSRF-RELKLQHKEYLCVKAMILLNSSM------------DSSRKLAH-LLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNAHVL------------------------------
49 PsiBlast_CBE 90.24100%-159 - C4 -1U3Q ESR2_HUMAN C:[3-237] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-ISR--PSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLL-ATTSRF-RELKLQHKEYLCVKAMILLNSSMY-----------DSSRKLAH-LLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNA---------------------------------
29 PsiBlast_CBE 90.24100%-155 - C4 -4J26 B:[1-238] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DALSPEQLVLTLLEAEPPHVL-ISR--PSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLL-ATTSRF-RELKLQHKEYLCVKAMILLNSSM-----------ADSSRKLAH-LLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNAH--------------------------------
17 PsiBlast_PDB 90.24100%-157 - C4 -1U3Q ESR2_HUMAN A:[3-237] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-ISR--PSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLL-ATTSRF-RELKLQHKEYLCVKAMILLNSSMY-----------DSSRKLAH-LLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNA---------------------------------
210 HHSearch 90.21100%-158 - C4 -1YYE ESR2_HUMAN A:[2-238] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVL-ISR--PSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLL-ATTSRF-RELKLQHKEYLCVKAMILLNSSM------------DSSRKLAH-LLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNAHVL------------------------------
44 PsiBlast_CBE 90.18100%-155 - C4 -1X7B B:[3-237] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-ISR--PSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLL-ATTSRF-RELKLQHKEYLCVKAMILLNSSM------------DSSRKLAH-LLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNA---------------------------------
54 PsiBlast_CBE 90.1799%-154 - C4 -1ZAF ESR2_HUMAN A:[1-238] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-ISR--PSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLL-ATTSRF-RELKLQHKEYLCVKAMILLNSAM------------DSSRKLAH-LLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNAHVL------------------------------
212 HHSearch 90.14100%-158 - C4 -1L2J ESR2_HUMAN A:[27-267] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DALSPEQLVLTLLEAEPPHVL-ISR-------TEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLL-ATTSRF-RELKLQHKEYLCVKAMILLNS----LVT-ATQD-ADSSRKLAH-LLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNAHVLR-----------------------------
14 PsiBlast_PDB 90.10100%-157 - C4 -1X78 ESR2_HUMAN A:[3-240] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-ISR--PSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLL-ATTSRF-RELKLQHKEYLCVKAMILLNSSM------------DSSRKLAH-LLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNAHVL------------------------------
53 PsiBlast_CBE 90.0699%-157 - C4 -1ZAF B:[1-238] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-ISR--PSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLL-ATTSRF-RELKLQHKEYLCVKAMILLNSAM------------DSSRKLAH-LLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNAHVL------------------------------
24 PsiBlast_CBE 90.03100%-159 - C4 -2Z4B B:[12-252] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LDALSPEQLVLTLLEAEPPHVL-ISR--P------ASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLL-ATTSRF-RELKLQHKEYLCVKAMILLNSSMYPLV---------SSRKLAH-LLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMK----V---PVYDLLLEMLNAHVL------------------------------
5 PsiBlast_PDB 90.03100%-158 - C4 -2I0G ESR2_HUMAN A:[13-250] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DALSPEQLVLTLLEAEPPHVL-ISR--P------ASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLL-ATTSRF-RELKLQHKEYLCVKAMILLNSSMYPLV---------SSRKLAH-LLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMK----V---PVYDLLLEMLNAH--------------------------------
9 PsiBlast_PDB 90.02100%-152 - C4 -1NDE A:[15-254] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DALSPEQLVLTLLEAEPPHVL-ISR--PS--FTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLL-ATTSRF-RELKLQHKEYLCVKAMILLNSSMY-----ATQD-ADSSRKLAH-LLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCK------PVYDLLLEMLNAHVL------------------------------
7 PsiBlast_PDB 90.01100%-157 - C4 -2Z4B ESR2_HUMAN A:[13-250] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DALSPEQLVLTLLEAEPPHVL-ISR--P------ASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLL-ATTSRF-RELKLQHKEYLCVKAMILLNSSMYPLV---------SSRKLAH-LLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMK----V---PVYDLLLEMLNAH--------------------------------
16 PsiBlast_PDB 89.89100%-158 - C4 -1X7J ESR2_HUMAN A:[3-237] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-ISR--PSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLL-ATTSRF-RELKLQHKEYLCVKAMILLNSSM------------DSSRKLAH-LLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNA---------------------------------
48 PsiBlast_CBE 89.74100%-161 - C4 -1U3Q D:[3-237] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-ISR--PSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLL-ATTSRF-RELKLQHKEYLCVKAMILLNSSMY-----------DSSRKLAH-LLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNA---------------------------------
43 PsiBlast_CBE 89.71100%-156 - C4 -1X7J B:[3-237] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-ISR--PSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLL-ATTSRF-RELKLQHKEYLCVKAMILLNSSM------------DSSRKLAH-LLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNA---------------------------------
51 PsiBlast_CBE 89.65100%-154 - C4 -2NV7 B:[1-235] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-ISR--PSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLL-ATTSRF-RELKLQHKEYLCVKAMILLNSSM------------DSSRKLAH-LLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNA---------------------------------
8 PsiBlast_PDB 89.64100%-159 - C4 -2QTU ESR2_HUMAN A:[13-250] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DALSPEQLVLTLLEAEPPHVL-ISR--P------ASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLL-ATTSRF-RELKLQHKEYLCVKAMILLNSSMYPLV---------SSRKLAH-LLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMK---------VYDLLLEMLNAH--------------------------------
25 PsiBlast_CBE 89.61100%-161 - C4 -2QTU B:[12-252] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LDALSPEQLVLTLLEAEPPHVL-ISR--P------ASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLL-ATTSRF-RELKLQHKEYLCVKAMILLNSSMYPLV---------SSRKLAH-LLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMK---------VYDLLLEMLNAHVL------------------------------
27 PsiBlast_CBE 89.58100%-157 - C4 -2I0G B:[12-250] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LDALSPEQLVLTLLEAEPPHVL-ISR--P------ASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLL-ATTSRF-RELKLQHKEYLCVKAMILLNSSMYPLV---------SSRKLAH-LLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMK----V---PVYDLLLEMLNAH--------------------------------
4 PsiBlast_PDB 89.5497%-158 - C4 -1L2J ESR2_HUMAN A:[27-267] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DALSPEQLVLTLLEAEPPHVL-ISR-------TEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLL-ATTSRF-RELKLQHKEYLCVKAMILLNS----LVT-ATQD-ADSSRKLAH-LLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNAHVLR-----------------------------
22 PsiBlast_CBE 89.53100%-160 - C4 -1YY4 B:[1-235] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-ISR--PSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLL-ATTSRF-RELKLQHKEYLCVKAMILLNSSM------------DSSRKLAH-LLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNA---------------------------------
55 PsiBlast_CBE 89.4999%-154 - C4 -2YLY B:[1-238] -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LDALSPEQLVLTLLEAEPPHVL-I--------FTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLL-ATTSRF-RELKLQHKEYLCVKAMILLNSS--------------SSRKLAH-LLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNAH--------------------------------
13 PsiBlast_PDB 89.48100%-156 - C4 -1X76 ESR2_HUMAN A:[3-237] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-ISR--PSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLL-ATTSRF-RELKLQHKEYLCVKAMILLNSSM------------DSSRKLAH-LLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNA---------------------------------
46 PsiBlast_CBE 89.40100%-155 - C4 -1X76 B:[3-237] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-ISR--PSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLL-ATTSRF-RELKLQHKEYLCVKAMILLNSSM------------DSSRKLAH-LLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNA---------------------------------
59 PsiBlast_CBE 89.1191%-158 - C4 -2J7Y A:[8-244] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TLSPEQLVLTLLEAEPPNVL-VS-------FTEASMMMSLTKLADKELVHMIGWAKKIPGFVELSLLDQVRLLESCWMEVLMVGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLL-ATTSRF-RELKLQHKEYLCVKAMILLNSSMYPLA--------ESSRKLTH-LLNAVTDALVWVIAKSGISSQQQSVRLANLLMLLSHVRHISNKGMEHLLSMKCKNVV---PVYDLLLEMLNAH--------------------------------
21 PsiBlast_CBE 88.91100%-153 - C4 -1YYE B:[1-234] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-ISR--PSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLL-ATTSRF-RELKLQHKEYLCVKAMILLNSSM------------DSSRKLAH-LLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLN----------------------------------
60 PsiBlast_CBE 88.7691%-157 - C4 -2J7X A:[8-244] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TLSPEQLVLTLLEAEPPNVL-VS-----MPFTEASMMMSLTKLADKELVHMIGWAKKIPGFVELSLLDQVRLLESCWMEVLMVGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLL-ATTSRF-RELKLQHKEYLCVKAMILLNSSMYPLA--------ESSRKLTH-LLNAVTDALVWVIAKSGISSQQQSVRLANLLMLLSHVRHISNKGMEHLLSMKCKNVV---PVYDLLLEMLNAH--------------------------------
23 PsiBlast_CBE 88.7297%-162 - C4 -1L2J ESR2_HUMAN B:[21-263] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRELLLDALSPEQLVLTLLEAEPPHV----------------MMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLL-ATTSRF-RELKLQHKEYLCVKAMILLNSSM--LVT-ATQD-ADSSRKLAH-LLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNM-----V---PVYDLLLEMLNA---------------------------------
50 PsiBlast_CBE 88.64100%-159 - C4 -1U3Q ESR2_HUMAN B:[1-237] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DALSPEQLVLTLLEAEPPHVL-ISR--PSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLL-ATTSRF-RELKLQHKEYLCVKAMILLNSSM------------DSSRKLAH-LLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNA---------------------------------
1 PsiBlast_PDB 88.64100%-154 - C4 -1YY4 ESR2_HUMAN A:[1-235] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVL-ISR--PSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLL-ATTSRF-RELKLQHKEYLCVKAMILLNSSM------------DSSRKLAH-LLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV---PVYDLLLEMLNA---------------------------------