@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : H_NR2B1_RXRa: (2016-11-25 )
MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT
Atome Classification :
(76 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MDTK
H
F
LPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLH
S
P
I
S
T
L
SSPINGMGP
P
F
S
V
ISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNG
V
L
KVPAHPSG
N
M
A
S
F
T
K
H
I
C
A
I
CGDRSSGKHY
G
V
Y
SC
E
G
C
K
G
F
F
K
R
T
V
R
KD
L
T
Y
TCRDNK
D
C
L
I
D
K
R
QR
N
R
C
Q
Y
C
R
Y
Q
K
C
L
A
MG
M
K
R
E
A
V
Q
E
E
R
Q
RGKDRNENEVESTSSANEDM
P
V
E
R
I
L
E
A
E
LAVEPKT
E
T
Y
V
E
ANMGLNPSSPND
P
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
RIP
H
F
SELPLDD
Q
V
I
L
L
RAGWN
E
L
L
I
A
SFSH
R
S
I
A
VKD
G
I
L
L
A
T
G
L
H
V
HRNSAHSA
G
V
G
A
I
F
D
R
V
L
T
E
L
V
S
K
M
R
D
MQM
D
K
T
E
L
G
C
L
R
A
I
V
L
FNPDSKGLS
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
KHKYPEQP
G
R
F
A
K
L
L
L
R
L
P
A
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
IGDT
P
I
D
T
F
L
M
E
M
L
EAPHQMT
1
PsiBlast_PDB
86.49
100%
-127
- C5 -
3DZU
1
RXRA_HUMAN
A:
[137-460]
-----------------------------------------------------------------------------------------------------------------------------------
K
H
I
C
A
I
C
G
D
R
S
S
G
K
H
Y
G
V
Y
S
C
E
G
C
K
G
F
F
K
R
T
V
R
K
D
L
T
Y
T
C
R
D
N
K
D
C
L
I
D
K
R
Q
R
N
R
C
Q
Y
C
R
Y
Q
K
C
L
A
M
G
M
K
R
E
A
V
Q
E
E
R
Q
R
--------------
A
N
E
D
M
P
V
E
R
I
L
E
A
E
L
A
---------------------
D
P
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
H
S
A
G
V
G
A
I
F
D
R
V
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
P
D
S
K
G
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
-------
2
PsiBlast_PDB
86.11
100%
-126
- C5 -
3E00
1
RXRA_HUMAN
A:
[137-460]
-----------------------------------------------------------------------------------------------------------------------------------
K
H
I
C
A
I
C
G
D
R
S
S
G
K
H
Y
G
V
Y
S
C
E
G
C
K
G
F
F
K
R
T
V
R
K
D
L
T
Y
T
C
R
D
N
K
D
C
L
I
D
K
R
Q
R
N
R
C
Q
Y
C
R
Y
Q
K
C
L
A
M
G
M
K
R
E
A
V
Q
E
E
R
Q
R
--------------
A
N
E
D
M
P
V
E
R
I
L
E
A
E
L
A
V
E
---------------------
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
H
S
A
G
V
G
A
I
F
D
R
V
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
P
D
S
K
G
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
-------
81
PsiBlast_CBE
80.99
100%
-134
- C5 -
4K4J
1
?
A:
[1-231]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
D
M
P
V
E
R
I
L
E
A
E
L
A
V
E
-----------------
P
N
D
P
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
H
S
A
G
V
G
A
I
F
D
R
V
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
P
D
S
K
G
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
E
A
P
----
10
PsiBlast_PDB
80.94
100%
-130
- C5 -
1MV9
1
RXRA_HUMAN
A:
[7-238]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
M
P
V
E
R
I
L
E
A
E
L
A
V
E
P
------------------
D
P
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
H
S
A
G
V
G
A
I
F
D
R
V
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
P
D
S
K
G
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
E
A
P
H
Q
--
14
PsiBlast_PDB
80.89
100%
-145
- C5 -
2P1U
1
RXRA_HUMAN
A:
[7-236]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
M
P
V
E
R
I
L
E
A
E
L
A
V
E
-------------------
D
P
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
H
S
A
G
V
G
A
I
F
D
R
V
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
P
D
S
K
G
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
E
A
P
----
27
PsiBlast_CBE
80.72
100%
-130
- C5 -
4ZSH
1
RXRA_HUMAN
A:
[7-236]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
M
P
V
E
R
I
L
E
A
E
L
A
V
E
-----------------
P
N
D
P
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
H
S
A
G
V
G
A
I
F
D
R
V
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
P
D
S
K
G
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
E
A
P
----
82
PsiBlast_CBE
80.63
100%
-129
- C5 -
3OAP
1
RXRA_HUMAN
A:
[1-231]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
D
M
P
V
E
R
I
L
E
A
E
L
A
V
E
-----------------
P
N
D
P
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
H
S
A
G
V
G
A
I
F
D
R
V
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
P
D
S
K
G
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
E
A
P
----
39
PsiBlast_CBE
80.63
100%
-130
- C5 -
1MZN
1
RXRA_HUMAN
E:
[5-236]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
E
D
M
P
V
E
R
I
L
E
A
E
L
A
V
E
P
K
T
E
T
Y
V
E
A
N
--------
N
D
P
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
H
S
A
G
V
G
A
I
F
D
R
V
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
P
D
S
K
G
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
E
A
P
----
59
PsiBlast_CBE
80.55
100%
-116
- C5 -
1XVP
1
RXRA_HUMAN
C:
[1-236]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
E
D
M
P
V
E
R
I
L
E
A
E
L
A
V
E
P
K
T
E
T
Y
V
E
A
N
M
G
L
N
P
S
S
P
N
D
P
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
H
S
A
G
V
G
A
I
F
D
R
V
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
P
D
S
K
G
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
E
A
P
H
Q
M
T
65
PsiBlast_CBE
80.54
100%
-130
- C5 -
4RME
1
RXRA_HUMAN
A:
[1-231]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
D
M
P
V
E
R
I
L
E
A
E
L
A
V
E
-----------------
P
N
D
P
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
H
S
A
G
V
G
A
I
F
D
R
V
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
P
D
S
K
G
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
E
A
P
----
17
PsiBlast_PDB
80.48
100%
-140
- C5 -
2ZXZ
1
RXRA_HUMAN
A:
[7-236]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
M
P
V
E
R
I
L
E
A
E
L
A
V
E
-----------------
P
N
D
P
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
H
S
A
G
V
G
A
I
F
D
R
V
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
P
D
S
K
G
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
E
A
P
----
11
PsiBlast_PDB
80.47
100%
-133
- C5 -
1MVC
1
RXRA_HUMAN
A:
[7-236]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
M
P
V
E
R
I
L
E
A
E
L
A
V
E
P
------------------
D
P
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
H
S
A
G
V
G
A
I
F
D
R
V
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
P
D
S
K
G
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
E
A
P
----
7
PsiBlast_PDB
80.46
100%
-141
- C5 -
3KWY
1
RXRA_HUMAN
A:
[11-240]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
M
P
V
E
R
I
L
E
A
E
L
A
V
E
P
------------------
D
P
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
H
S
A
G
V
G
A
I
F
D
R
V
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
P
D
S
K
G
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
--
I
D
T
F
L
M
E
M
L
E
A
P
----
75
PsiBlast_CBE
80.36
100%
-130
- C5 -
4PP3
1
RXRA_HUMAN
A:
[1-231]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
D
M
P
V
E
R
I
L
E
A
E
L
A
V
E
-----------------
P
N
D
P
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
H
S
A
G
V
G
A
I
F
D
R
V
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
P
D
S
K
G
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
E
A
P
----
37
PsiBlast_CBE
80.36
100%
-130
- C5 -
2ZY0
1
RXRA_HUMAN
C:
[5-236]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
E
D
M
P
V
E
R
I
L
E
A
E
L
A
V
E
-----------------
P
N
D
P
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
H
S
A
G
V
G
A
I
F
D
R
V
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
P
D
S
K
G
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
E
A
P
----
15
PsiBlast_PDB
80.36
100%
-136
- C5 -
2P1V
1
RXRA_HUMAN
A:
[7-236]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
M
P
V
E
R
I
L
E
A
E
L
A
V
E
-------------------
D
P
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
H
S
A
G
V
G
A
I
F
D
R
V
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
P
D
S
K
G
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
E
A
P
----
125
HHSearch
80.31
100%
-140
- C5 -
2P1T
1
RXRA_HUMAN
A:
[7-236]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
M
P
V
E
R
I
L
E
A
E
L
A
V
E
-------------------
D
P
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
H
S
A
G
V
G
A
I
F
D
R
V
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
P
D
S
K
G
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
E
A
P
----
76
PsiBlast_CBE
80.31
100%
-134
- C5 -
4POJ
1
RXRA_HUMAN
A:
[1-231]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
D
M
P
V
E
R
I
L
E
A
E
L
A
V
E
-----------------
P
N
D
P
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
H
S
A
G
V
G
A
I
F
D
R
V
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
P
D
S
K
G
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
E
A
P
----
13
PsiBlast_PDB
80.31
100%
-140
- C5 -
2P1T
1
RXRA_HUMAN
A:
[7-236]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
M
P
V
E
R
I
L
E
A
E
L
A
V
E
-------------------
D
P
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
H
S
A
G
V
G
A
I
F
D
R
V
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
P
D
S
K
G
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
E
A
P
----
66
PsiBlast_CBE
80.28
100%
-129
- C5 -
4RMD
1
RXRA_HUMAN
A:
[1-231]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
D
M
P
V
E
R
I
L
E
A
E
L
A
V
E
-----------------
P
N
D
P
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
H
S
A
G
V
G
A
I
F
D
R
V
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
P
D
S
K
G
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
E
A
P
----
79
PsiBlast_CBE
80.24
100%
-135
- C5 -
4M8E
1
RXRA_HUMAN
A:
[1-231]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
D
M
P
V
E
R
I
L
E
A
E
L
A
V
E
-----------------
P
N
D
P
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
H
S
A
G
V
G
A
I
F
D
R
V
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
P
D
S
K
G
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
E
A
P
----
83
PsiBlast_CBE
80.23
100%
-142
- C5 -
3PCU
1
RXRA_HUMAN
A:
[1-230]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
M
P
V
E
R
I
L
E
A
E
L
A
V
E
-------------------
D
P
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
H
S
A
G
V
G
A
I
F
D
R
V
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
P
D
S
K
G
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
E
A
P
----
12
PsiBlast_PDB
80.23
100%
-129
- C5 -
1MZN
1
RXRA_HUMAN
A:
[5-236]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
E
D
M
P
V
E
R
I
L
E
A
E
L
A
V
E
P
K
T
E
T
Y
V
E
A
N
--------
N
D
P
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
H
S
A
G
V
G
A
I
F
D
R
V
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
P
D
S
K
G
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
E
A
P
----
53
PsiBlast_CBE
80.21
100%
-111
- C5 -
1K74
1
RXRA_HUMAN
A:
[3-234]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
E
D
M
P
V
E
R
I
L
E
A
E
L
A
V
E
P
K
T
E
T
Y
V
E
A
N
M
G
L
N
P
S
S
P
N
D
P
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
H
S
A
G
V
G
A
I
F
D
R
V
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
P
D
S
K
G
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
E
A
P
----
18
PsiBlast_PDB
80.17
100%
-129
- C5 -
2ZY0
1
RXRA_HUMAN
A:
[5-236]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
E
D
M
P
V
E
R
I
L
E
A
E
L
A
V
E
-----------------
P
N
D
P
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
H
S
A
G
V
G
A
I
F
D
R
V
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
P
D
S
K
G
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
E
A
P
----
38
PsiBlast_CBE
80.14
100%
-129
- C5 -
1MZN
1
RXRA_HUMAN
G:
[7-236]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
M
P
V
E
R
I
L
E
A
E
L
A
V
E
P
------------------
D
P
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
H
S
A
G
V
G
A
I
F
D
R
V
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
P
D
S
K
G
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
E
A
P
----
29
PsiBlast_CBE
80.11
100%
-131
- C5 -
3R5M
1
RXRA_HUMAN
A:
[5-236]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
E
D
M
P
V
E
R
I
L
E
A
E
L
A
V
E
-----------------
P
N
D
P
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
H
S
A
G
V
G
A
I
F
D
R
V
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
P
D
S
K
G
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
E
A
P
----
5
PsiBlast_PDB
80.11
100%
-134
- C5 -
4OC7
1
RXRA_HUMAN
A:
[21-250]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
M
P
V
E
R
I
L
E
A
E
L
A
V
E
-----------------
P
N
D
P
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
H
S
A
G
V
G
A
I
F
D
R
V
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
P
D
S
K
G
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
E
A
P
----
47
PsiBlast_CBE
80.07
100%
-142
- C5 -
3OZJ
1
RXRA_HUMAN
C:
[3-234]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
E
D
M
P
V
E
R
I
L
E
A
E
L
A
V
E
-----------------
P
N
D
P
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
H
S
A
G
V
G
A
I
F
D
R
V
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
P
D
S
K
G
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
E
A
P
----
74
PsiBlast_CBE
80.06
100%
-129
- C5 -
4PP5
1
RXRA_HUMAN
A:
[1-231]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
D
M
P
V
E
R
I
L
E
A
E
L
A
V
E
-----------------
P
N
D
P
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
H
S
A
G
V
G
A
I
F
D
R
V
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
P
D
S
K
G
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
E
A
P
----
46
PsiBlast_CBE
80.06
100%
-136
- C5 -
1RDT
1
RXRA_HUMAN
A:
[8-236]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
D
M
P
V
E
R
I
L
E
A
E
L
A
V
E
P
------------------
D
P
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
H
S
A
G
V
G
A
I
F
D
R
V
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
P
D
S
K
G
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
E
------
56
PsiBlast_CBE
80.04
100%
-113
- C5 -
1FM9
1
RXRA_HUMAN
A:
[3-234]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
E
D
M
P
V
E
R
I
L
E
A
E
L
A
V
E
P
K
T
E
T
Y
V
E
A
N
M
G
L
N
P
S
S
P
N
D
P
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
H
S
A
G
V
G
A
I
F
D
R
V
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
P
D
S
K
G
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
E
A
P
----
16
PsiBlast_PDB
80.00
100%
-138
- C5 -
3FUG
1
RXRA_HUMAN
A:
[7-236]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
M
P
V
E
R
I
L
E
A
E
L
A
V
E
-------------------
D
P
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
H
S
A
G
V
G
A
I
F
D
R
V
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
P
D
S
K
G
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
E
A
P
----
80
PsiBlast_CBE
79.99
100%
-131
- C5 -
4K6I
1
?
A:
[1-231]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
D
M
P
V
E
R
I
L
E
A
E
L
A
V
E
-----------------
P
N
D
P
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
H
S
A
G
V
G
A
I
F
D
R
V
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
P
D
S
K
G
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
E
A
P
----
48
PsiBlast_CBE
79.95
100%
-132
- C5 -
3OZJ
1
RXRA_HUMAN
A:
[3-234]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
E
D
M
P
V
E
R
I
L
E
A
E
L
A
V
E
-----------------
P
N
D
P
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
H
S
A
G
V
G
A
I
F
D
R
V
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
P
D
S
K
G
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
E
A
P
----
40
PsiBlast_CBE
79.91
100%
-133
- C5 -
1MZN
1
RXRA_HUMAN
C:
[7-236]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
M
P
V
E
R
I
L
E
A
E
L
A
V
E
P
------------------
D
P
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
H
S
A
G
V
G
A
I
F
D
R
V
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
P
D
S
K
G
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
E
A
P
----
73
PsiBlast_CBE
79.84
100%
-135
- C5 -
4RFW
1
RXRA_HUMAN
A:
[1-231]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
D
M
P
V
E
R
I
L
E
A
E
L
A
V
E
-----------------
P
N
D
P
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
H
S
A
G
V
G
A
I
F
D
R
V
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
P
D
S
K
G
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
E
A
P
----
72
PsiBlast_CBE
79.78
100%
-126
- C5 -
4RMC
1
RXRA_HUMAN
A:
[1-231]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
D
M
P
V
E
R
I
L
E
A
E
L
A
V
E
-----------------
P
N
D
P
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
H
S
A
G
V
G
A
I
F
D
R
V
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
P
D
S
K
G
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
E
A
P
----
77
PsiBlast_CBE
79.75
100%
-135
- C5 -
4POH
1
RXRA_HUMAN
A:
[1-231]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
D
M
P
V
E
R
I
L
E
A
E
L
A
V
E
-----------------
P
N
D
P
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
H
S
A
G
V
G
A
I
F
D
R
V
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
P
D
S
K
G
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
E
A
P
----
6
PsiBlast_PDB
79.72
100%
-138
- C5 -
3E94
1
RXRA_HUMAN
A:
[11-240]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
M
P
V
E
R
I
L
E
A
E
L
A
V
E
-------------------
D
P
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
H
S
A
G
V
G
A
I
F
D
R
V
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
P
D
S
K
G
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
E
A
P
----
28
PsiBlast_CBE
79.61
100%
-143
- C5 -
3R5M
1
RXRA_HUMAN
C:
[6-236]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
D
M
P
V
E
R
I
L
E
A
E
L
A
V
E
------------------
N
D
P
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
H
S
A
G
V
G
A
I
F
D
R
V
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
P
D
S
K
G
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
E
A
P
----
58
PsiBlast_CBE
79.42
100%
-118
- C5 -
1FM6
1
RXRA_HUMAN
A:
[3-234]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
E
D
M
P
V
E
R
I
L
E
A
E
L
A
V
E
P
K
T
E
T
Y
V
E
A
N
M
G
L
N
P
S
S
P
N
D
P
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
H
S
A
G
V
G
A
I
F
D
R
V
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
P
D
S
K
G
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
E
A
P
----
78
PsiBlast_CBE
79.36
100%
-132
- C5 -
4M8H
1
RXRA_HUMAN
A:
[1-231]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
D
M
P
V
E
R
I
L
E
A
E
L
A
V
E
-----------------
P
N
D
P
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
H
S
A
G
V
G
A
I
F
D
R
V
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
P
D
S
K
G
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
E
A
P
----
64
PsiBlast_CBE
79.10
99%
-131
- C5 -
1XDK
1
RXRA_MOUSE
A:
[2-234]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
N
E
D
M
P
V
E
K
I
L
E
A
E
L
A
V
E
P
----------------
P
N
D
P
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
H
S
A
G
V
G
A
I
F
D
R
V
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
P
D
S
K
G
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
E
A
P
----
63
PsiBlast_CBE
79.06
99%
-132
- C5 -
1XDK
1
RXRA_MOUSE
E:
[2-234]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
N
E
D
M
P
V
E
K
I
L
E
A
E
L
A
V
E
P
----------------
P
N
D
P
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
H
S
A
G
V
G
A
I
F
D
R
V
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
P
D
S
K
G
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
E
A
P
----
71
PsiBlast_CBE
78.99
99%
-138
- C5 -
1DKF
1
RXRA_MOUSE
A:
[1-233]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
A
N
E
D
M
P
V
E
K
I
L
E
A
E
L
A
V
E
P
----------------
P
N
D
P
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
A
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
H
S
A
G
V
G
A
I
F
D
R
V
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
P
D
S
K
G
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
E
A
-----
57
PsiBlast_CBE
78.96
100%
-116
- C5 -
1FM6
1
RXRA_HUMAN
U:
[3-234]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
E
D
M
P
V
E
R
I
L
E
A
E
L
A
V
E
P
K
T
E
T
Y
V
E
A
N
M
G
L
N
P
S
S
P
N
D
P
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
H
S
A
G
V
G
A
I
F
D
R
V
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
P
D
S
K
G
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
E
A
P
----
85
PsiBlast_CBE
78.82
92%
-140
- C5 -
5EC9
1
?
A:
[1-210]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
M
P
V
E
R
I
L
E
A
E
L
A
V
E
P
------------------
D
P
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
H
S
A
G
V
G
A
I
F
D
R
V
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
P
D
S
K
G
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
E
------
61
PsiBlast_CBE
78.79
100%
-112
- C5 -
1XV9
1
RXRA_HUMAN
C:
[1-232]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
E
D
M
P
V
E
R
I
L
E
A
E
L
A
V
E
P
K
T
E
T
Y
V
E
A
N
M
G
L
N
P
S
S
P
N
D
P
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
H
S
A
G
V
G
A
I
F
D
R
V
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
P
D
S
K
G
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
E
A
P
----
86
PsiBlast_CBE
78.78
87%
-144
- C5 -
1UHL
1
A:
[1-231]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
M
P
V
D
R
I
L
E
A
E
L
A
V
E
Q
---------------
S
P
N
D
P
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
S
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
D
V
R
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
H
S
A
G
V
G
A
I
F
D
R
V
L
T
E
L
V
S
K
M
R
D
M
R
M
D
K
T
E
L
G
C
L
R
A
I
I
L
F
N
P
D
A
K
G
L
S
N
P
S
E
V
E
V
L
R
E
K
V
Y
A
S
L
E
T
Y
C
K
Q
K
Y
P
E
Q
Q
G
R
F
A
K
L
L
L
R
L
P
A
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
E
A
-----
62
PsiBlast_CBE
78.67
100%
-108
- C5 -
1XV9
1
RXRA_HUMAN
A:
[1-232]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
E
D
M
P
V
E
R
I
L
E
A
E
L
A
V
E
P
K
T
E
T
Y
V
E
A
N
M
G
L
N
P
S
S
P
N
D
P
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
H
S
A
G
V
G
A
I
F
D
R
V
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
P
D
S
K
G
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
E
A
P
----
43
PsiBlast_CBE
78.54
100%
-130
- C5 -
3UVV
1
RXRA_HUMAN
B:
[7-238]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
E
D
M
P
V
E
R
I
L
E
A
E
L
A
V
E
P
K
T
--------------
P
N
D
P
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
H
S
A
G
V
G
A
I
F
D
R
V
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
P
D
S
K
G
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
E
A
P
----
60
PsiBlast_CBE
78.15
100%
-105
- C5 -
1XVP
1
RXRA_HUMAN
A:
[1-232]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
E
D
M
P
V
E
R
I
L
E
A
E
L
A
V
E
P
K
T
E
T
Y
V
E
A
N
M
G
L
N
P
S
S
P
N
D
P
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
H
S
A
G
V
G
A
I
F
D
R
V
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
P
D
S
K
G
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
E
A
P
----
41
PsiBlast_CBE
77.68
100%
-122
- C5 -
1FBY
1
RXRA_HUMAN
B:
[6-235]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
M
P
V
E
R
I
L
E
A
E
L
A
V
E
P
------------------
D
P
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
H
S
A
G
V
G
A
I
F
D
R
V
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
P
D
S
K
G
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
E
A
P
----
42
PsiBlast_CBE
77.51
100%
-119
- C5 -
1FBY
1
RXRA_HUMAN
A:
[1-235]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
S
A
N
E
D
M
P
V
E
R
I
L
E
A
E
L
A
V
E
P
------------------
D
P
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
H
S
A
G
V
G
A
I
F
D
R
V
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
P
D
S
K
G
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
E
A
P
----
44
PsiBlast_CBE
75.47
99%
-113
- C5 -
3A9E
1
RXRA_MOUSE
A:
[3-234]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
A
N
E
D
M
P
V
E
K
I
L
E
A
E
L
A
V
E
P
K
--------------
S
P
N
D
P
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
H
S
A
G
V
G
A
I
F
D
R
V
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
P
D
S
K
G
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
E
------
54
PsiBlast_CBE
74.97
100%
-130
- C5 -
1G5Y
1
RXRA_HUMAN
C:
[7-232]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
V
E
R
I
L
E
A
E
L
A
V
E
P
K
T
E
T
Y
V
E
A
N
M
G
L
N
P
S
S
P
N
D
P
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
H
S
A
G
V
G
A
I
F
D
R
V
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
P
D
S
K
G
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
E
------
26
PsiBlast_CBE
74.84
100%
-144
- C5 -
4N5G
1
?
C:
[13-240]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
V
E
R
I
L
E
A
E
L
A
-------------------
P
N
D
P
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
H
S
A
G
V
G
A
I
F
D
R
V
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
P
D
S
K
G
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
E
A
P
----
23
PsiBlast_CBE
74.22
100%
-161
- C5 -
4N8R
1
?
C:
[44-239]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
D
P
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
H
S
A
G
V
G
A
I
F
D
R
V
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
P
D
S
K
G
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
E
A
-----
45
PsiBlast_CBE
74.19
100%
-122
- C5 -
3FC6
1
RXRA_HUMAN
C:
[5-237]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
A
N
E
D
M
P
V
E
R
I
L
E
A
E
L
A
V
E
P
------------------
D
P
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
H
S
A
G
V
G
A
I
F
D
R
V
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
P
D
S
K
G
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
L
R
S
I
G
L
K
C
L
E
-------------
D
T
F
L
M
E
M
L
E
A
-----
33
PsiBlast_CBE
73.93
100%
-116
- C5 -
3R2A
1
RXRA_HUMAN
A:
[4-231]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
N
E
D
M
P
V
E
R
I
L
E
A
E
L
A
V
E
P
K
-----------------
D
P
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
H
S
A
G
V
G
A
I
F
D
R
V
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
P
D
S
K
G
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
---------
93
PsiBlast_CBE
73.91
87%
-157
- C5 -
1H9U
1
RXRB_HUMAN
A:
[1-224]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
P
V
D
R
I
L
E
A
E
L
A
V
---------------------
P
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
S
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
D
V
R
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
H
S
A
G
V
G
A
I
F
D
R
V
L
T
E
L
V
S
K
M
R
D
M
R
M
D
K
T
E
L
G
C
L
R
A
I
I
L
F
N
P
D
A
K
G
L
S
N
P
S
E
V
E
V
L
R
E
K
V
Y
A
S
L
E
T
Y
C
K
Q
K
Y
P
E
Q
Q
G
R
F
A
K
L
L
L
R
L
P
A
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
-----------
91
PsiBlast_CBE
73.90
87%
-154
- C5 -
1H9U
1
RXRB_HUMAN
C:
[1-224]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
P
V
D
R
I
L
E
A
E
L
A
V
---------------------
P
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
S
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
D
V
R
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
H
S
A
G
V
G
A
I
F
D
R
V
L
T
E
L
V
S
K
M
R
D
M
R
M
D
K
T
E
L
G
C
L
R
A
I
I
L
F
N
P
D
A
K
G
L
S
N
P
S
E
V
E
V
L
R
E
K
V
Y
A
S
L
E
T
Y
C
K
Q
K
Y
P
E
Q
Q
G
R
F
A
K
L
L
L
R
L
P
A
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
-----------
90
PsiBlast_CBE
73.75
87%
-152
- C5 -
1H9U
1
D:
[1-224]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
P
V
D
R
I
L
E
A
E
L
A
V
---------------------
P
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
S
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
D
V
R
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
H
S
A
G
V
G
A
I
F
D
R
V
L
T
E
L
V
S
K
M
R
D
M
R
M
D
K
T
E
L
G
C
L
R
A
I
I
L
F
N
P
D
A
K
G
L
S
N
P
S
E
V
E
V
L
R
E
K
V
Y
A
S
L
E
T
Y
C
K
Q
K
Y
P
E
Q
Q
G
R
F
A
K
L
L
L
R
L
P
A
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
-----------
92
PsiBlast_CBE
73.32
87%
-153
- C5 -
1H9U
1
RXRB_HUMAN
B:
[1-224]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
P
V
D
R
I
L
E
A
E
L
A
V
---------------------
P
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
S
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
D
V
R
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
H
S
A
G
V
G
A
I
F
D
R
V
L
T
E
L
V
S
K
M
R
D
M
R
M
D
K
T
E
L
G
C
L
R
A
I
I
L
F
N
P
D
A
K
G
L
S
N
P
S
E
V
E
V
L
R
E
K
V
Y
A
S
L
E
T
Y
C
K
Q
K
Y
P
E
Q
Q
G
R
F
A
K
L
L
L
R
L
P
A
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
-----------
31
PsiBlast_CBE
73.19
100%
-128
- C5 -
3R2A
1
RXRA_HUMAN
C:
[6-231]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
D
M
P
V
E
R
I
L
E
A
E
L
A
V
E
P
-----------------------
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
H
S
A
G
V
G
A
I
F
D
R
V
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
P
D
S
K
G
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
---------
55
PsiBlast_CBE
73.12
100%
-120
- C5 -
1G5Y
1
RXRA_HUMAN
B:
[7-235]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
V
E
R
I
L
E
A
E
L
A
V
E
P
K
T
E
T
Y
V
E
A
N
M
G
L
N
P
S
S
P
N
D
P
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
H
S
A
G
V
G
A
I
F
D
R
V
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
P
D
S
K
G
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
E
A
P
H
---
84
PsiBlast_CBE
73.06
100%
-113
- C5 -
3H0A
1
A:
[1-228]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
D
M
P
V
E
R
I
L
E
A
E
L
A
V
E
------------------
N
D
P
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
H
S
A
G
V
G
A
I
F
D
R
V
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
P
D
S
K
G
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
-------
22
PsiBlast_CBE
72.83
100%
-160
- C5 -
4N8R
1
?
D:
[45-241]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
P
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
H
S
A
G
V
G
A
I
F
D
R
V
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
P
D
S
K
G
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
E
A
P
H
---
87
PsiBlast_CBE
72.76
82%
-117
- C5 -
1XIU
1
RXR_BIOGL
B:
[3-226]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
N
D
M
P
V
E
Q
I
L
E
A
E
L
A
V
D
P
K
I
D
T
Y
I
D
A
Q
--------
K
D
P
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
T
E
L
P
L
E
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
G
F
S
H
R
S
I
M
A
K
D
G
I
L
L
A
T
G
L
H
V
H
R
S
S
A
H
Q
A
G
V
G
T
I
F
D
R
V
L
T
E
L
V
A
K
M
R
D
M
K
M
D
K
T
E
L
G
C
L
R
A
V
V
L
F
N
P
D
A
K
G
L
T
A
V
Q
E
V
E
Q
L
R
E
K
V
Y
A
S
L
E
E
Y
T
K
S
R
Y
P
E
E
P
G
R
F
A
K
L
L
L
R
L
P
A
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
Q
P
I
D
T
F
L
M
E
M
L
E
N
P
----
24
PsiBlast_CBE
72.62
100%
-156
- C5 -
4N8R
1
?
B:
[43-240]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
N
D
P
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
H
S
A
G
V
G
A
I
F
D
R
V
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
P
D
S
K
G
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
E
A
P
----
25
PsiBlast_CBE
72.60
100%
-155
- C5 -
4N5G
1
?
D:
[45-240]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
P
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
H
S
A
G
V
G
A
I
F
D
R
V
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
P
D
S
K
G
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
E
A
P
----
88
PsiBlast_CBE
72.20
82%
-127
- C5 -
1XIU
1
RXR_BIOGL
A:
[4-224]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
D
M
P
V
E
Q
I
L
E
A
E
L
A
V
D
P
K
I
D
T
Y
I
D
A
Q
--------
K
D
P
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
T
E
L
P
L
E
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
G
F
S
H
R
S
I
M
A
K
D
G
I
L
L
A
T
G
L
H
V
H
R
S
S
A
H
Q
A
G
V
G
T
I
F
D
R
V
L
T
E
L
V
A
K
M
R
D
M
K
M
D
K
T
E
L
G
C
L
R
A
V
V
L
F
N
P
D
A
K
G
L
T
A
V
Q
E
V
E
Q
L
R
E
K
V
Y
A
S
L
E
E
Y
T
K
S
R
Y
P
E
E
P
G
R
F
A
K
L
L
L
R
L
P
A
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
Q
P
I
D
T
F
L
M
E
M
L
E
------
8
PsiBlast_PDB
71.39
100%
-160
- C5 -
4N5G
1
RXRA_HUMAN
A:
[45-240]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
P
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
H
S
A
G
V
G
A
I
F
D
R
V
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
P
D
S
K
G
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
E
A
P
----
9
PsiBlast_PDB
70.98
100%
-150
- C5 -
4N8R
1
RXRA_HUMAN
A:
[45-241]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
P
V
T
N
I
C
Q
A
A
D
K
Q
L
F
T
L
V
E
W
A
K
R
I
P
H
F
S
E
L
P
L
D
D
Q
V
I
L
L
R
A
G
W
N
E
L
L
I
A
S
F
S
H
R
S
I
A
V
K
D
G
I
L
L
A
T
G
L
H
V
H
R
N
S
A
H
S
A
G
V
G
A
I
F
D
R
V
L
T
E
L
V
S
K
M
R
D
M
Q
M
D
K
T
E
L
G
C
L
R
A
I
V
L
F
N
P
D
S
K
G
L
S
N
P
A
E
V
E
A
L
R
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
P
E
Q
P
G
R
F
A
K
L
L
L
R
L
P
A
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
T
P
I
D
T
F
L
M
E
M
L
E
A
P
H
---
94
PsiBlast_CBE
68.35
75%
-155
- C5 -
4OZT
1
?
U:
[1-193]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
A
V
A
N
I
C
Q
A
T
N
S
Q
L
Y
Q
L
V
E
W
A
K
H
I
P
H
F
S
S
L
P
I
E
D
Q
V
L
L
L
R
A
G
W
N
E
L
L
I
A
A
F
S
H
R
S
V
E
V
R
D
G
I
V
L
G
A
G
I
T
V
H
R
N
S
A
H
Q
A
G
V
G
T
I
F
D
R
V
L
T
E
L
V
A
K
M
R
D
M
N
M
D
R
T
E
L
G
S
L
R
S
I
I
L
F
N
P
E
V
R
G
L
K
S
G
Q
E
V
E
L
L
R
E
K
V
Y
A
A
L
E
E
Y
T
R
V
T
R
P
E
E
P
G
R
F
A
K
L
L
L
R
L
P
A
L
R
S
I
G
L
K
C
L
E
H
L
F
F
F
K
L
I
G
D
I
P
I
D
T
F
L
M
D
M
L
-------