@TOME V2.3
(Nov 2016)

Ref. - - Doc.
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Alignment:

3D Common Core:

Structural Clustering:

Modeller Result :

Complexes Modeling
Templates Information:
Sequence & Result Tab:

Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : Z_NR3A2_ESR2b: (2016-04-07 )
MSSSPGPAPVLDSSKADRGASPALLPRLYASPLGMDNQTVCIPSPYVEACQDYSPPHGGEFNHGALTLYSPVSSAVLGFHRPPVSESLVPLSPTILWPPHSLHCPPPLAYSETRSHSAWEEAKTHTLSQSSSVLSHTKLLGQQLEGDNGLNPSASIVGKGDTHFCAVCHDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKSRRKSCQACRLRKCYEVGMMKCGVRRERCSYRGARHRRNPQIRDSSGGVVGLRGQSQQHLEFPLSPSQHLFPSGGRAEGRALNYSPEQLVSCILEAEPPQIYLREPVKKPYTEASMMMSLTSLADKELVLMISWAKKIPGFVELTLSDQVHLLECCWLDILMLGLMWRSVDHPGKLIFTPDLKLNREEGNCVEGIMEIFDMLLATTSRFRELKLQREEYVCLKAMILLNSNNCSSLPQTPEDVESRGKVLNLLDSVTDALVWIISRTGLSSQQQSIRLAHLLMLLSHIRHLSNKGIEHLSNMKRKNVVLLYDLLLEMLDANASQSSRMLEDRQQSPENLHTSRPQPDLKDSDQETPHSPRAEEMVNKTLHSSLLREDMDTN

Atome Classification :

(200 SA) .........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290...-.....300.......310.......320.......330.......340.......350.......360.......370.......380....----...390.......400.......410.......420........430.......440.......450.......460.......470.......480.......490.......500.......510.......----520.......530.......540.......550.......560.......570.......580.......590
(Atome) (Ident) (Tito) (Num) (Ligand) (Uniprot) MSSSPGPAPVLDSSKADRGASPALLPRLYASPLGMDNQTVCIPSPYVEACQDYSPPHGGEFNHGALTLYSPVSSAVLGFHRPPVSESLVPLSPTILWPPHSLHCPPPLAYSETRSHSAWEEAKTHTLSQSSSVLSHTKLLGQQLEGDNGLNPSASIVGKGDTHFCAVCHDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKSRRKSCQACRLRKCYEVGMMKCGVRRERCSYRGARHRRNPQIRDSSGGVVGLRGQSQQHLEFPLSPSQHLFPSGGRAEGR-ALN-YSPEQLVSCILEAEPPQIYLREPVKKPYTEASMMMSLTSLADKELVLMISWAKKIPGFVELTLSDQVHLLECCWLDILMLGLMWRSVDHPGK----LIFTPDLKLNREEGNCVEGIMEIFDMLLATTSRF-RELKLQREEYVCLKAMILLNSNNCSSLPQTPEDVESRGKVLNLLDSVTDALVWIISRTGLSSQQQSIRLAHLLMLLSHIRHLSNKGIEHLSNMKRKNVV----LLYDLLLEMLDANASQSSRMLEDRQQSPENLHTSRPQPDLKDSDQETPHSPRAEEMVNKTLHSSLLREDMDTN
52 PsiBlast_CBE 94.4170%-164 - C- -2JJ3 ESR2_HUMAN A:[16-251] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVLISRP-------ASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNS-SMYPLV-------SSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMK--NVV----PVYDLLLEMLNAHV-----------------------------------------------------------
43 PsiBlast_CBE 93.3970%-150 - C5 -1QKM A:[10-245] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVLISRP-------ASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNS-SMYPLV-----ADSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV----PVYDLLLEMLNAHVL----------------------------------------------------------
46 PsiBlast_CBE 93.2070%-142 - C5 -1ZAF ESR2_HUMAN A:[2-237] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVLISRP-SAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNS-AM----------DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV----PVYDLLLEMLNAHVL----------------------------------------------------------
42 PsiBlast_CBE 93.0970%-147 - C5 -1U3R B:[4-239] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVLISRP-SAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNS-S------------SSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV----PVYDLLLEMLNAHVLR---------------------------------------------------------
35 PsiBlast_CBE 93.0270%-147 - C5 -1U3S B:[4-237] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVLISRP-SAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNS-S------------SSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV----PVYDLLLEMLNA-------------------------------------------------------------
217 HHSearch 92.7770%-144 - C5 -3OLL ESR2_HUMAN A:[3-238] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPHVLIS-RPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSMYPLVTA-T--ADSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV----PVYDLLLEMLNAH------------------------------------------------------------
213 HHSearch 92.6368%-148 - C5 -1L2J ESR2_HUMAN A:[27-267] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DA-LSPEQLVLTLLEAEPPHVLIS-R-----TEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNS----LVTA-TQDADSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV----PVYDLLLEMLNAHVLR---------------------------------------------------------
1 PsiBlast_PDB 92.4467%-151 - C5 -1L2J ESR2_HUMAN A:[27-265] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DALSPEQLVLTLLEAEPPHVLISR------TEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNS-----LVTATQDADSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV----PVYDLLLEMLNAHVLR---------------------------------------------------------
9 PsiBlast_PDB 92.4370%-145 - C5 -3OMO ESR2_HUMAN A:[4-237] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVLISRP-SAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNS-SMYPLVT-----DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV----PVYDLLLEMLNA-------------------------------------------------------------
61 PsiBlast_CBE 92.4270%-148 - C5 -3OLL B:[4-238] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVLISRP-SAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNS-SMYPLVTAT---DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV----PVYDLLLEMLNAH------------------------------------------------------------
11 PsiBlast_PDB 92.4070%-147 - C5 -3OMQ ESR2_HUMAN A:[4-237] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVLISRP-SAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNS-SMYPLVT-----DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV----PVYDLLLEMLNA-------------------------------------------------------------
50 PsiBlast_CBE 92.3570%-151 - C5 -2QTU ESR2_HUMAN A:[16-250] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVLISRP-------ASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNS-SMYPLV-------SSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMK----------VYDLLLEMLNAH------------------------------------------------------------
114 PsiBlast_CBE 92.3159%-139 - C5 -2QSE ESR1_HUMAN A:[11-251] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSE----RPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRN---CVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLSDLLLEMLDAHRL----------------------------------------------------------
54 PsiBlast_CBE 92.2970%-151 - C5 -2I0G ESR2_HUMAN A:[16-250] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVLISRP-------ASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNS-SMYPLV-------SSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMK----V----PVYDLLLEMLNAH------------------------------------------------------------
24 PsiBlast_CBE 92.2670%-150 - C5 -4J24 ESR2_HUMAN C:[4-238] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVLISRP-SAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNS-S------------SSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV----PVYDLLLEMLNAH------------------------------------------------------------
10 PsiBlast_PDB 92.2470%-147 - C5 -3OMP ESR2_HUMAN A:[4-237] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVLISRP-SAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNS-SMYPLVT-----DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV----PVYDLLLEMLNA-------------------------------------------------------------
12 PsiBlast_PDB 92.2070%-150 - C5 -2YJD ESR2_HUMAN A:[4-237] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVLISRP-SAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNS-S------------SSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV----PVYDLLLEMLNA-------------------------------------------------------------
17 PsiBlast_PDB 92.1970%-144 - C5 -2NV7 ESR2_HUMAN A:[2-237] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVLISRP-SAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNS-SM----------DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV----PVYDLLLEMLNAHVL----------------------------------------------------------
48 PsiBlast_CBE 92.0770%-152 - C5 -2Z4B ESR2_HUMAN A:[16-250] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVLISRP-------ASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNS-SMYPLV-------SSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMK----V----PVYDLLLEMLNAH------------------------------------------------------------
7 PsiBlast_PDB 91.9370%-141 - C5 -1U3S ESR2_HUMAN A:[4-237] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVLISRP-SAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNS-SMY--------ADSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV----PVYDLLLEMLNA-------------------------------------------------------------
51 PsiBlast_CBE 91.8770%-153 - C5 -2JJ3 B:[16-251] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVLISRP-------ASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNS-SMYPLV-------SSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMK--NVV----PVYDLLLEMLNAHVLR---------------------------------------------------------
13 PsiBlast_PDB 91.8670%-146 - C5 -4J24 ESR2_HUMAN A:[4-238] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVLISRP-SAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNS-S------------SSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV----PVYDLLLEMLNAH------------------------------------------------------------
3 PsiBlast_PDB 91.8270%-143 - C5 -1X78 ESR2_HUMAN A:[4-239] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVLISRP-SAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNS-SM----------DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV----PVYDLLLEMLNAHVL----------------------------------------------------------
101 PsiBlast_CBE 91.7759%-136 - C5 -4PXM ESR1_HUMAN A:[24-264] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVY-------------DHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLYGLLLEMLDAHRL----------------------------------------------------------
5 PsiBlast_PDB 91.7670%-144 - C5 -1X7J ESR2_HUMAN A:[4-237] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVLISRP-SAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNS-SM----------DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV----PVYDLLLEMLNA-------------------------------------------------------------
30 PsiBlast_CBE 91.7570%-150 - C5 -2YJD B:[4-237] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVLISRP-SAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNS-S------------SSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV----PVYDLLLEMLNA-------------------------------------------------------------
14 PsiBlast_PDB 91.7370%-145 - C5 -4J26 ESR2_HUMAN A:[4-238] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVLISRP-SAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNS-S----------ADSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV----PVYDLLLEMLNAH------------------------------------------------------------
19 PsiBlast_PDB 91.6870%-141 - C5 -1U3R ESR2_HUMAN A:[4-239] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVLISRP-SAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNS-SM-------QDADSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV----PVYDLLLEMLNAHVL----------------------------------------------------------
60 PsiBlast_CBE 91.6069%-149 - C5 -2J7X A:[8-244] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-LSPEQLVLTLLEAEPPNVLVS----MPFTEASMMMSLTKLADKELVHMIGWAKKIPGFVELSLLDQVRLLESCWMEVLMVGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNS-SMYPLA------ESSRKLTHLLNAVTDALVWVIAKSGISSQQQSVRLANLLMLLSHVRHISNKGMEHLLSMKCKNVV----PVYDLLLEMLNAH------------------------------------------------------------
173 PsiBlast_CBE 91.4659%-134 - C5 -4PP6 ESR1_HUMAN A:[3-243] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTF----------KDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLSDLLLEMLDAHR-----------------------------------------------------------
8 PsiBlast_PDB 91.4570%-148 - C5 -3OLS ESR2_HUMAN A:[4-237] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVLISRP-SAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNS-SMYPLVT-----DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV----PVYDLLLEMLNA-------------------------------------------------------------
45 PsiBlast_CBE 91.4070%-147 - C5 -1ZAF B:[2-237] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVLISRP-SAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNS-AM----------DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV----PVYDLLLEMLNAHVL----------------------------------------------------------
6 PsiBlast_PDB 91.3970%-145 - C5 -1U3Q ESR2_HUMAN A:[4-237] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVLISRP-SAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNS-SMY---------DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV----PVYDLLLEMLNA-------------------------------------------------------------
31 PsiBlast_CBE 91.3870%-147 - C5 -1X7J B:[4-237] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVLISRP-SAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNS-SM----------DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV----PVYDLLLEMLNA-------------------------------------------------------------
25 PsiBlast_CBE 91.3170%-145 - C5 -4J24 ESR2_HUMAN B:[4-238] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVLISRP-SAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNS-SM----------DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV----PVYDLLLEMLNAH------------------------------------------------------------
59 PsiBlast_CBE 91.2569%-148 - C5 -2J7Y A:[8-244] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-LSPEQLVLTLLEAEPPNVLVS------FTEASMMMSLTKLADKELVHMIGWAKKIPGFVELSLLDQVRLLESCWMEVLMVGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNS-SMYPLA------ESSRKLTHLLNAVTDALVWVIAKSGISSQQQSVRLANLLMLLSHVRHISNKGMEHLLSMKCKNVV----PVYDLLLEMLNAH------------------------------------------------------------
20 PsiBlast_PDB 91.2170%-140 - C5 -1NDE A:[18-253] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVLISRP-S--FTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNS-SMY----ATQDADSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCK-------PVYDLLLEMLNAHVL----------------------------------------------------------
4 PsiBlast_PDB 91.1570%-140 - C5 -1X7B ESR2_HUMAN A:[4-239] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVLISRP-SAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNS-SM----------DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV----PVYDLLLEMLNAHVL----------------------------------------------------------
37 PsiBlast_CBE 91.1270%-146 - C5 -1U3Q ESR2_HUMAN C:[4-237] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVLISRP-SAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNS-SMY---------DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV----PVYDLLLEMLNA-------------------------------------------------------------
186 PsiBlast_CBE 91.0859%-142 - C5 -2QXS ESR1_HUMAN A:[11-251] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDP-RPFS-ASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTF---TLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PSYDLLLEMLDAH------------------------------------------------------------
23 PsiBlast_CBE 91.0870%-148 - C5 -4J24 D:[4-237] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVLISRP-SAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNS--------------SSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV----PVYDLLLEMLNA-------------------------------------------------------------
49 PsiBlast_CBE 91.0670%-152 - C5 -2QTU B:[16-251] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVLISRP-------ASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNS-SMYPLV-------SSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMK----------VYDLLLEMLNAHVL----------------------------------------------------------
47 PsiBlast_CBE 91.0570%-151 - C5 -2Z4B B:[16-251] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVLISRP-------ASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNS-SMYPLV-------SSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMK----V----PVYDLLLEMLNAHVL----------------------------------------------------------
53 PsiBlast_CBE 90.9970%-152 - C5 -2I0G B:[16-250] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVLISRP-------ASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNS-SMYPLV-------SSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMK----V----PVYDLLLEMLNAH------------------------------------------------------------
2 PsiBlast_PDB 90.9970%-146 - C5 -1X76 ESR2_HUMAN A:[4-237] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVLISRP-SAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNS-SM----------DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV----PVYDLLLEMLNA-------------------------------------------------------------
41 PsiBlast_CBE 90.9570%-142 - C5 -2NV7 B:[2-235] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVLISRP-SAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNS-SM----------DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV----PVYDLLLEMLNA-------------------------------------------------------------
212 HHSearch 90.9369%-142 - C5 -1YYE ESR2_HUMAN A:[2-238] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVLIS-RPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSSM-----------DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV----PVYDLLLEMLNAHVL----------------------------------------------------------
113 PsiBlast_CBE 90.9159%-130 - C5 -2QSE B:[11-251] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTF---TLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLSDLLLEMLDAHRLH---------------------------------------------------------
16 PsiBlast_PDB 90.9170%-141 - C5 -1YYE ESR2_HUMAN A:[2-237] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVLISRP-SAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNS-SM----------DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV----PVYDLLLEMLNAHVL----------------------------------------------------------
133 PsiBlast_CBE 90.8559%-140 - C5 -4IWF B:[5-245] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYD----FSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYT-----------KDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLSDLLLEMLDAHR-----------------------------------------------------------
44 PsiBlast_CBE 90.8570%-154 - C5 -2GIU A:[5-240] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVLISRP-------ASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKC-EGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNS-SMYPLV-----ADSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNM----VV----PVYDLLLEMLNAHVL----------------------------------------------------------
15 PsiBlast_PDB 90.8370%-141 - C5 -1YY4 ESR2_HUMAN A:[2-235] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVLISRP-SAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNS-SM----------DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV----PVYDLLLEMLNA-------------------------------------------------------------
200 PsiBlast_CBE 90.8158%-144 - C5 -5AK2 ESR1_HUMAN A:[21-261] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSE----------SMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLESAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKSVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYT-------SLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSM-----V----PSYDLLLEMLDAHRLHAP-------------------------------------------------------
62 PsiBlast_CBE 90.7159%-138 - C5 -4DMA B:[5-245] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTF-----------DHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKAKNVV----PLYDLLLEMLDAHR-----------------------------------------------------------
168 PsiBlast_CBE 90.6859%-133 - C5 -4PPS B:[3-243] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTF--------EEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLSDLLLEMLDAHR-----------------------------------------------------------
22 PsiBlast_CBE 90.6870%-146 - C5 -4J26 B:[4-238] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVLISRP-SAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNS-SM---------ADSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV----PVYDLLLEMLNAH------------------------------------------------------------
18 PsiBlast_PDB 90.6370%-144 - C5 -1U9E ESR2_HUMAN A:[4-237] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVLISRP-SAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNS-S------------SSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV----PVYDLLLEMLNA-------------------------------------------------------------
100 PsiBlast_CBE 90.6159%-142 - C5 -4PXM B:[24-264] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSE-------SEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYT-----------KDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLYGLLLEMLDAHR-----------------------------------------------------------
21 PsiBlast_CBE 90.4767%-158 - C5 -1L2J ESR2_HUMAN B:[21-263] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MREL-LLDALSPEQLVLTLLEAEPPHV--------------MMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNS-SM--LVTATQDADSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNM-----V----PVYDLLLEMLNA-------------------------------------------------------------
118 PsiBlast_CBE 90.4659%-136 - C5 -2QH6 ESR1_HUMAN A:[11-251] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYD--RPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTF----------KDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKN-V----PLSDLLLEMLDAHR-----------------------------------------------------------
144 PsiBlast_CBE 90.3359%-137 - C5 -4IVW ESR1_HUMAN A:[5-245] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYT------------DHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLSDLLLEMLDAHR-----------------------------------------------------------
126 PsiBlast_CBE 90.2159%-133 - C5 -2QA6 ESR1_HUMAN A:[11-251] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYD--RPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLSDLLLEMLDAHRL----------------------------------------------------------
65 PsiBlast_CBE 90.1959%-129 - C5 -2YJA B:[11-251] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLYDLLLEMLDAHRL----------------------------------------------------------
153 PsiBlast_CBE 90.1559%-132 - C5 -1X7E B:[3-243] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPVK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTFL-------EEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLYDLLLEMLDAHRL----------------------------------------------------------
194 PsiBlast_CBE 90.1658%-135 - C5 -3OS8 D:[12-252] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYD--------SMMGLLTNLADRELVHMINWAKRVPGFVDLTRHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTF-----KSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PSYDLLLEMLDAH------------------------------------------------------------
98 PsiBlast_CBE 90.1559%-134 - C5 -1GWR B:[3-243] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDP--PFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTF---TLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLYDLLLEMLDAHR-----------------------------------------------------------
154 PsiBlast_CBE 90.1259%-132 - C5 -1X7E ESR1_HUMAN A:[3-243] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPVK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTFL-------EEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLYDLLLEMLDAHRL----------------------------------------------------------
202 PsiBlast_CBE 90.1358%-136 - C5 -3OS8 ESR1_HUMAN A:[12-251] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTRHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PSYDLLLEMLDA-------------------------------------------------------------
201 PsiBlast_CBE 90.1058%-137 - C5 -3OS8 ESR1_HUMAN B:[12-251] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTRHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PSYDLLLEMLDA-------------------------------------------------------------
32 PsiBlast_CBE 90.1270%-144 - C5 -1X7B B:[4-237] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVLISRP-SAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNS-SM----------DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV----PVYDLLLEMLNA-------------------------------------------------------------
142 PsiBlast_CBE 90.1159%-136 - C5 -4IVY ESR1_HUMAN A:[5-245] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQ---VEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVY-------------DHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLSDLLLEMLDAHR-----------------------------------------------------------
121 PsiBlast_CBE 90.1059%-130 - C5 -2QGT B:[11-251] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTF-----KSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLSDLLLEMLDAHR-----------------------------------------------------------
171 PsiBlast_CBE 90.0959%-142 - C5 -4PPP ESR1_HUMAN A:[3-243] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSE------FSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTF----------KDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLSDLLLEMLDAHR-----------------------------------------------------------
28 PsiBlast_CBE 90.0770%-151 - C5 -3OMO B:[4-235] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVLISRP-SAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNS-SMYPLVTA--------KLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV----PVYDLLLEML---------------------------------------------------------------
115 PsiBlast_CBE 90.0459%-130 - C5 -2QR9 B:[11-251] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTF---TLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLSDLLLEMLDAHRLH---------------------------------------------------------
129 PsiBlast_CBE 90.0159%-127 - C5 -2P15 B:[11-251] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTF---TLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLSDLLLEMLDAHRLH---------------------------------------------------------
27 PsiBlast_CBE 90.0170%-151 - C5 -3OMP B:[4-235] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVLISRP-SAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNS-SMYPLVTA--------KLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV----PVYDLLLEML---------------------------------------------------------------
117 PsiBlast_CBE 89.9859%-139 - C5 -2QH6 B:[11-251] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYD----FSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTF-----------DHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLSDLLLEMLDAH------------------------------------------------------------
26 PsiBlast_CBE 89.9770%-151 - C5 -3OMQ B:[4-235] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVLISRP-SAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNS-SMYPLVTA--------KLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV----PVYDLLLEML---------------------------------------------------------------
169 PsiBlast_CBE 89.9259%-131 - C5 -4PPS ESR1_HUMAN A:[3-243] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMI-WAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTF-----KSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLSDLLLEMLDAHR-----------------------------------------------------------
40 PsiBlast_CBE 89.9170%-149 - C5 -1YY4 B:[2-235] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVLISRP-SAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNS-SM----------DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV----PVYDLLLEMLNA-------------------------------------------------------------
122 PsiBlast_CBE 89.8459%-133 - C5 -2QGT ESR1_HUMAN A:[11-251] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTFL-------EEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLSDLLLEMLDAHR-----------------------------------------------------------
112 PsiBlast_CBE 89.8359%-138 - C5 -2QXM ESR1_HUMAN A:[11-251] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEY---RPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRN-----EGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTFL----KSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLSDLLLEMLDAHRL----------------------------------------------------------
36 PsiBlast_CBE 89.8270%-147 - C5 -1U3Q D:[4-237] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVLISRP-SAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNS-SMY---------DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV----PVYDLLLEMLNA-------------------------------------------------------------
56 PsiBlast_CBE 89.8070%-155 - C5 -2YLY ESR2_HUMAN A:[5-237] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVLI-------FTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSS-------------SSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV----PVYDLLLEMLNA-------------------------------------------------------------
82 PsiBlast_CBE 89.7859%-132 - C5 -1GWQ ESR1_HUMAN A:[7-247] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSE-----PFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLYDLLLEMLDAHR-----------------------------------------------------------
127 PsiBlast_CBE 89.7459%-135 - C5 -2Q6J B:[11-251] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGV-----------EEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLSDLLLEMLDAHR-----------------------------------------------------------
76 PsiBlast_CBE 89.7459%-133 - C5 -3ERD B:[14-254] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTF--------EEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLYDLLLEMLDAHRLH---------------------------------------------------------
198 PsiBlast_CBE 89.7359%-134 - C5 -3L03 ESR1_HUMAN A:[10-250] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYT--------LEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLSDLLLEMLDAHR-----------------------------------------------------------
185 PsiBlast_CBE 89.7259%-144 - C5 -2QXS B:[11-251] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEY--------ASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVY---------LEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PSYDLLLEMLDAHR-----------------------------------------------------------
33 PsiBlast_CBE 89.7170%-141 - C5 -1X78 B:[4-239] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVLISRP-SAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNS-SM----------DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV----PVYDLLLEMLNAHVL----------------------------------------------------------
29 PsiBlast_CBE 89.6470%-149 - C5 -3OLS B:[4-235] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVLISRP-SAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNS-SMYPLVTA--------KLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV----PVYDLLLEML---------------------------------------------------------------
99 PsiBlast_CBE 89.5959%-134 - C5 -1GWR ESR1_HUMAN A:[3-243] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEY---RPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTF---TLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLYDLLLEMLDAHRL----------------------------------------------------------
147 PsiBlast_CBE 89.5859%-134 - C5 -4IV2 B:[5-245] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRN--KCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVY----STLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLSDLLLEMLDAHR-----------------------------------------------------------
134 PsiBlast_CBE 89.5759%-132 - C5 -4IWF ESR1_HUMAN A:[5-245] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTF--------EEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLSDLLLEMLDAHR-----------------------------------------------------------
151 PsiBlast_CBE 89.4459%-130 - C5 -4IU7 ESR1_HUMAN A:[5-245] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTF----------KDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLSDLLLEMLDAHR-----------------------------------------------------------
34 PsiBlast_CBE 89.4470%-147 - C5 -1X76 B:[4-237] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVLISRP-SAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNS-SM----------DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV----PVYDLLLEMLNA-------------------------------------------------------------
196 PsiBlast_CBE 89.3759%-139 * C5 *2QA8 ESR1_HUMAN A:[11-251] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSE------FSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTF--------EEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLSDLLLEMLDAHR-----------------------------------------------------------
124 PsiBlast_CBE 89.3759%-136 - C5 -2QAB ESR1_HUMAN A:[11-251] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTF--------EEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLSDLLLEMLDAHR-----------------------------------------------------------
146 PsiBlast_CBE 89.3659%-134 - C5 -4IV4 ESR1_HUMAN A:[5-245] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYS----TRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTF----------KDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKN-V----PLSDLLLEMLDAHR-----------------------------------------------------------
172 PsiBlast_CBE 89.3559%-139 - C5 -4PP6 B:[3-243] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYD----FSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYT----------EKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLSDLLLEMLDAHR-----------------------------------------------------------
90 PsiBlast_CBE 89.3359%-131 - C5 -1XP1 A:[1-241] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLYDLLLEMLDAHRLHA--------------------------------------------------------
170 PsiBlast_CBE 89.3059%-137 - C5 -4PPP B:[5-243] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S-LTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTF-----KSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLSDLLLEMLDAHR-----------------------------------------------------------
188 PsiBlast_CBE 89.2858%-130 - C5 -3OSA ESR1_HUMAN C:[12-251] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEY---------SMMGLLTNLADRELVHMINWAKRVPGFVDLTRHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQG---EGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PSYDLLLEMLDA-------------------------------------------------------------
187 PsiBlast_CBE 89.2658%-134 - C5 -3OSA D:[12-252] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEY---------SMMGLLTNLADRELVHMINWAKRVPGFVDLTRHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQG---EGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTF-----KSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PSYDLLLEMLDAH------------------------------------------------------------
119 PsiBlast_CBE 89.1459%-131 - C5 -2QGW B:[11-251] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYT---STLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLSDLLLEMLDAHRL----------------------------------------------------------
63 PsiBlast_CBE 89.1359%-133 - C5 -4DMA ESR1_HUMAN A:[5-245] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTFL-------EEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKAKNVV----PLYDLLLEMLDAHRL----------------------------------------------------------
77 PsiBlast_CBE 89.1259%-131 - C5 -3ERD ESR1_HUMAN A:[14-254] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLYDLLLEMLDAHRLH---------------------------------------------------------
55 PsiBlast_CBE 89.0970%-152 - C5 -2YLY B:[5-238] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVLI-------FTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNSS-------------SSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV----PVYDLLLEMLNAH------------------------------------------------------------
116 PsiBlast_CBE 89.0859%-134 - C5 -2QR9 ESR1_HUMAN A:[11-251] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEY---RPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLSDLLLEMLDAHRL----------------------------------------------------------
125 PsiBlast_CBE 89.0459%-128 - C5 -2QA6 B:[11-251] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTF---TLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLSDLLLEMLDAHRLH---------------------------------------------------------
137 PsiBlast_CBE 89.0259%-129 - C5 -4IW8 B:[5-245] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYT------------DHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLSDLLLEMLDAHR-----------------------------------------------------------
130 PsiBlast_CBE 88.9959%-133 - C5 -2P15 ESR1_HUMAN A:[11-251] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEY---RPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLSDLLLEMLDAHRL----------------------------------------------------------
38 PsiBlast_CBE 88.9970%-144 - C5 -1U3Q ESR2_HUMAN B:[4-237] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVLISRP-SAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNS-SM----------DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV----PVYDLLLEMLNA-------------------------------------------------------------
143 PsiBlast_CBE 88.9559%-133 - C5 -4IVW B:[5-245] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQG--VEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTF-----KSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLSDLLLEMLDAHR-----------------------------------------------------------
135 PsiBlast_CBE 88.9359%-132 - C5 -4IWC B:[5-245] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTFL--TLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCK-------PLSDLLLEMLDAHRL----------------------------------------------------------
184 PsiBlast_CBE 88.8758%-139 - C5 -1PCG ESR1_HUMAN A:[4-244] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDPT-PFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLESAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKSVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTFL-----------HIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKSKNVV----PLYDLLLEMLDAH------------------------------------------------------------
39 PsiBlast_CBE 88.8670%-144 - C5 -1YYE B:[2-234] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPEQLVLTLLEAEPPHVLISRP-SAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNS-SM----------DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVV----PVYDLLLEMLN--------------------------------------------------------------
108 PsiBlast_CBE 88.8559%-135 - C5 -4ZN9 ? B:[7-247] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSG---------------DHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLSDLLLEMLDAHRLHAPTS-----------------------------------------------------
57 PsiBlast_CBE 88.7367%-138 - C5 -1QKN A:[8-243] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-LSPEQLVLTLLEAEPPNVLVSRP-SMPFTEASMMMSLTKLADKELVHMIGWAKKIPGFVELSLLDQVRLLESCWMEVLMVGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNS-SMYPLASANQEAESSRKLTHLLNAVTDALVWVIAKSGISSQQQSVRLANLLMLLSHVRHISNKGMEHLLSMK------------DLLLEMLNA-------------------------------------------------------------
89 PsiBlast_CBE 88.7059%-130 - C5 -1XP6 A:[1-241] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLYDLLLEMLDAHRLHA--------------------------------------------------------
120 PsiBlast_CBE 88.6359%-135 - C5 -2QGW ESR1_HUMAN A:[11-251] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTF--------EEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLSDLLLEMLDAHR-----------------------------------------------------------
93 PsiBlast_CBE 88.5559%-127 - C5 -1QKU ESR1_HUMAN B:[7-247] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLYDLLLEMLDAHRLH---------------------------------------------------------
109 PsiBlast_CBE 88.5359%-138 - C5 -4ZN9 ? A:[7-247] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVY-------------DHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLSDLLLEMLDAHRLHAPTS-----------------------------------------------------
197 PsiBlast_CBE 88.5259%-127 - C5 -3L03 B:[10-250] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTFLS---KSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLSDLLLEMLDAHRLH---------------------------------------------------------
138 PsiBlast_CBE 88.4759%-133 - C5 -4IW8 ESR1_HUMAN A:[5-245] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCV--MVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTF---TLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLSDLLLEMLDAHR-----------------------------------------------------------
88 PsiBlast_CBE 88.4459%-128 - C5 -1XP9 A:[1-241] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLYDLLLEMLDAHRLHA--------------------------------------------------------
183 PsiBlast_CBE 88.4358%-129 - C5 -1PCG B:[4-244] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLESAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKSVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTFLS-TLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKSKNVV----PLYDLLLEMLDAH------------------------------------------------------------
141 PsiBlast_CBE 88.4059%-131 - C5 -4IVY B:[5-245] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQG-----MVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYT-------SLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLSDLLLEMLDAHR-----------------------------------------------------------
139 PsiBlast_CBE 88.4059%-134 - C5 -4IW6 B:[5-245] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQ---VEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTF------SLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLSDLLLEMLDAHR-----------------------------------------------------------
86 PsiBlast_CBE 88.4059%-132 - C5 -1YIM A:[1-241] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLYDLLLEMLDAHRLHA--------------------------------------------------------
176 PsiBlast_CBE 88.3858%-143 - C5 -1XQC ESR1_HUMAN B:[8-248] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSE----------SMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLESAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKSVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTF--STLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHL-------------PLYDLLLEMLDAHR-----------------------------------------------------------
155 PsiBlast_CBE 88.3858%-143 - C5 -2R6Y B:[4-242] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYS-----------SMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLESAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKSVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTF--STLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSM----------PLYDLLLEMLD--------------------------------------------------------------
175 PsiBlast_CBE 88.3658%-137 - C5 -1XQC ESR1_HUMAN C:[8-248] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSE----------SMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLESAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKSVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTF--STLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSM----------PLYDLLLEMLDAHR-----------------------------------------------------------
123 PsiBlast_CBE 88.3359%-129 - C5 -2QAB B:[11-251] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLSDLLLEMLDAHRL----------------------------------------------------------
111 PsiBlast_CBE 88.2859%-128 - C5 -2QXM B:[11-251] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTF---TLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLSDLLLEMLDAHRLH---------------------------------------------------------
80 PsiBlast_CBE 88.2659%-133 - C5 -1R5K ESR1_HUMAN A:[14-252] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYD----FSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLYDLLLEMLD--------------------------------------------------------------
177 PsiBlast_CBE 88.1858%-140 - C5 -1XQC ESR1_HUMAN A:[8-248] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSE----------SMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLESAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKSVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTF--STLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSM----------PLYDLLLEMLDAHR-----------------------------------------------------------
167 PsiBlast_CBE 88.1858%-134 - C5 -2YAT A:[8-248] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSE----------SMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLESAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRN---------EIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTF--STLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKSKNVV----PLYDLLLEMLDAHR-----------------------------------------------------------
87 PsiBlast_CBE 88.1159%-134 - C5 -1XPC A:[1-241] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLYDLLLEMLDAHRLHA--------------------------------------------------------
81 PsiBlast_CBE 88.0459%-132 - C5 -1GWQ B:[7-247] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSE------FSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLYDLLLEMLDAHR-----------------------------------------------------------
150 PsiBlast_CBE 88.0059%-133 - C5 -4IU7 B:[5-245] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRN--KCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVY------LKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLSDLLLEMLDAHRL----------------------------------------------------------
192 PsiBlast_CBE 87.9358%-138 - C5 -3OS9 ESR1_HUMAN B:[12-251] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTRHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQG---EGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTF------SLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSM----VV----PSYDLLLEMLDA-------------------------------------------------------------
190 PsiBlast_CBE 87.8758%-148 - C5 -3OS9 D:[12-249] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSE----------SMMGLLTNLADRELVHMINWAKRVPGFVDLTRHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQ------MVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYT--------LEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLY-------V----PSYDLLLEML---------------------------------------------------------------
193 PsiBlast_CBE 87.8558%-140 - C5 -3OS9 ESR1_HUMAN A:[12-251] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTRHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTF--STLKSLEEK-HIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSM----VV----PSYDLLLEMLDA-------------------------------------------------------------
195 PsiBlast_CBE 87.8058%-131 - C5 -3OS8 ESR1_HUMAN C:[12-251] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYD--------SMMGLLTNLADRELVHMINWAKRVPGFVDLTRHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PSYDLLLEMLDA-------------------------------------------------------------
164 PsiBlast_CBE 87.7558%-134 - C5 -2POG ESR1_HUMAN A:[4-244] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEY--------ASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLESAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKSVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMK----V----PLYDLLLEMLDAHRLH---------------------------------------------------------
156 PsiBlast_CBE 87.7658%-135 - C5 -2R6Y ESR1_HUMAN A:[4-244] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDP-------SMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLESAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKSVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSM-----V----PLYDLLLEMLDAHRL----------------------------------------------------------
145 PsiBlast_CBE 87.7559%-129 - C5 -4IV4 B:[5-245] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGK----MVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGV--------KSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLSDLLLEMLDAHR-----------------------------------------------------------
158 PsiBlast_CBE 87.7158%-139 - C5 -2R6W ESR1_HUMAN A:[4-244] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEY--------ASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLESAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKSVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLY-------V----PLYDLLLEMLDAHRL----------------------------------------------------------
140 PsiBlast_CBE 87.6859%-134 - C5 -4IW6 ESR1_HUMAN A:[5-245] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYT------------DHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLSDLLLEMLDAHR-----------------------------------------------------------
136 PsiBlast_CBE 87.6459%-133 - C5 -4IWC ESR1_HUMAN A:[5-245] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTF--------EEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLSDLLLEMLDAHR-----------------------------------------------------------
128 PsiBlast_CBE 87.6459%-132 - C5 -2Q6J ESR1_HUMAN A:[11-251] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYT--SSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLSDLLLEMLDAHRL----------------------------------------------------------
157 PsiBlast_CBE 87.5158%-140 - C5 -2R6W B:[4-243] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEY--------ASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLESAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKSVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTF--STLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLY------------PLYDLLLEMLDA-------------------------------------------------------------
132 PsiBlast_CBE 87.5159%-130 - C5 -3HLV ESR1_HUMAN A:[10-250] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDP---FSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTFL--TLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLSDLLLEMLDAHR-----------------------------------------------------------
189 PsiBlast_CBE 87.4858%-136 - C5 -3OSA ESR1_HUMAN B:[12-251] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTRHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGK-VEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCK-VV----PSYDLLLEMLDA-------------------------------------------------------------
199 PsiBlast_CBE 87.4658%-150 - C5 -5AK2 B:[22-259] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LS-LTADQMVSALLDAEPPILYSE-----PFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLESAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKSVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVY------------KDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSM---------------LLEMLD--------------------------------------------------------------
95 PsiBlast_CBE 87.4159%-126 - C5 -1G50 C:[4-244] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLYDLLLEMLDAH------------------------------------------------------------
94 PsiBlast_CBE 87.3959%-126 - C5 -1QKU ESR1_HUMAN A:[7-247] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLYDLLLEMLDAHRLH---------------------------------------------------------
210 HHSearch 87.3751%-138 - C5 -2OCF A:[10-251] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYT-----------KDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLSDLLLEMLDAHR-----------------------------------------------------------
215 HHSearch 87.3559%-134 - C5 -1XPC A:[5-245] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLYDLLLEMLDAHRLHA--------------------------------------------------------
165 PsiBlast_CBE 87.3358%-131 - C5 -2AYR A:[4-244] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLESAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKSVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKSKNVV----PLYDLLLEMLDAHRLHA--------------------------------------------------------
174 PsiBlast_CBE 87.2458%-141 - C5 -1XQC D:[8-248] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSE----------SMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLESAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKSVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTF--STLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHL-------------PLYDLLLEMLDAHR-----------------------------------------------------------
152 PsiBlast_CBE 87.2359%-134 - C5 -1X7R A:[3-243] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSE-------SEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPVK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLYDLLLEMLDAH------------------------------------------------------------
74 PsiBlast_CBE 87.1859%-137 - C5 -2IOK ESR1_HUMAN A:[7-244] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEY-------EASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMK---------PLYDLLLEML---------------------------------------------------------------
148 PsiBlast_CBE 87.1459%-136 - C5 -4IV2 ESR1_HUMAN A:[5-245] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVY-------------DHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLSDLLLEMLDAHR-----------------------------------------------------------
58 PsiBlast_CBE 87.0867%-145 - C5 -1HJ1 A:[9-226] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSPEQLVLTLLEAEPPNVLVSRP-SMPFTEASMMMSLTKLADKELVHMIGWAKKIPGFVELSLLDQVRLLESCWMEVLMVGLMWRSIDHPGK----LIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRF-RELKLQHKEYLCVKAMILLNS---------------SRKLTHLLNAVTDALVWVIAKSGISSQQQSVRLANLLMLLSHVRHISNKGMEHLLSMK----------------------------------------------------------------------------------
75 PsiBlast_CBE 87.0659%-133 - C5 -3ERT A:[14-254] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLYDLLLEMLDAHRLHAP-------------------------------------------------------
96 PsiBlast_CBE 87.0259%-125 - C5 -1G50 ESR1_HUMAN B:[4-244] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLYDLLLEMLDAHRL----------------------------------------------------------
91 PsiBlast_CBE 86.8959%-135 - C5 -1SJ0 A:[1-241] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKC--VV----PLYDLLLEMLDAHRLHA--------------------------------------------------------
162 PsiBlast_CBE 86.8058%-127 - C5 -2Q70 ESR1_HUMAN A:[4-244] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDP----SEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLESAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKSVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSM-----V----PLYDLLLEMLDAHRL----------------------------------------------------------
131 PsiBlast_CBE 86.7759%-132 - C5 -3HLV B:[10-250] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTFLS-----LEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLSDLLLEMLDAHR-----------------------------------------------------------
181 PsiBlast_CBE 86.7058%-134 - C5 -2I0J ESR1_HUMAN B:[4-244] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYD-------ASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLESAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKSVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTF--STLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSM----------PLYDLLLEMLDAH------------------------------------------------------------
179 PsiBlast_CBE 86.6858%-136 - C5 -2I0J D:[4-244] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYD--------SMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLESAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKSVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTF--STLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSM-----------LYDLLLEMLDAH------------------------------------------------------------
66 PsiBlast_CBE 86.5359%-134 - C5 -2OUZ A:[7-247] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLYDLLLEMLDAHRLHA--------------------------------------------------------
64 PsiBlast_CBE 86.4759%-139 - C5 -3DT3 ESR1_HUMAN A:[11-251] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSE-------SEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTF-SSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMK--NVV----PLYDLLLEMLDAHRLHA--------------------------------------------------------
85 PsiBlast_CBE 86.4559%-132 - C5 -1YIN A:[1-241] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSM----VV----PLYDLLLEMLDAHRLHA--------------------------------------------------------
191 PsiBlast_CBE 86.3658%-136 - C5 -3OS9 ESR1_HUMAN C:[12-251] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEY---------SMMGLLTNLADRELVHMINWAKRVPGFVDLTRHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQ------MVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTF-SSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYS-----VV----PSYDLLLEMLDA-------------------------------------------------------------
78 PsiBlast_CBE 86.3659%-137 - C5 -1R5K C:[14-251] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYD----FSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLYDLLLEML---------------------------------------------------------------
92 PsiBlast_CBE 86.2359%-125 - C5 -1QKU C:[7-247] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLYDLLLEMLDAHRLH---------------------------------------------------------
149 PsiBlast_CBE 85.9959%-138 - C5 -4IUI B:[6-245] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LS-LTADQMVSALLDAEPPILYSEYDPTR----ASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDR--------MVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYT---------EEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLSDLLLEMLDAHRL----------------------------------------------------------
97 PsiBlast_CBE 85.8559%-125 - C5 -1G50 ESR1_HUMAN A:[4-244] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLYDLLLEMLDAHRLH---------------------------------------------------------
110 PsiBlast_CBE 85.8459%-132 - C5 -2IOG A:[3-239] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLYDLLLEMLDAHRLHA--------------------------------------------------------
79 PsiBlast_CBE 85.5659%-136 - C5 -1R5K ESR1_HUMAN B:[14-251] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYD----FSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLYDLLLEML---------------------------------------------------------------
207 PsiBlast_CBE 85.5456%-124 - C5 -2BJ4 ESR1_HUMAN A:[24-247] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SLALS-LTADQMVSALLDAEPPILYSE-----PFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTFLS-TLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSM-----------------------------------------------------------------------------------
206 PsiBlast_CBE 85.3656%-133 - C5 -2JF9 ESR1_HUMAN A:[24-247] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SLALS-LTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYT---------EEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSM-----------------------------------------------------------------------------------
166 PsiBlast_CBE 85.1858%-133 - C5 -1QKT A:[4-244] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLESAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKSVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKSKNVV----PLYDLLLEMLDAHRLHA--------------------------------------------------------
83 PsiBlast_CBE 85.0759%-125 - C5 -1A52 B:[11-248] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHERLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLYDLLLEML---------------------------------------------------------------
204 PsiBlast_CBE 84.8556%-139 - C5 -2JF9 C:[24-248] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SLALS-LTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGV-----------EEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMK----------------------------------------------------------------------------------
159 PsiBlast_CBE 84.6058%-136 - C5 -2QE4 B:[4-225] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSE----------SMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLESAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKSVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTF---------EKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSM-----------------------------------------------------------------------------------
160 PsiBlast_CBE 84.5758%-136 - C5 -2QE4 ESR1_HUMAN A:[4-225] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSE-----PFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLESAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKSVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYT-----------KDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSM-----------------------------------------------------------------------------------
84 PsiBlast_CBE 84.3659%-125 - C5 -1A52 ESR1_HUMAN A:[11-248] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHERLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV----PLYDLLLEML---------------------------------------------------------------
73 PsiBlast_CBE 84.2259%-129 - C5 -2IOK B:[7-244] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDPTR----ASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYS-----------PLYDLLLEML---------------------------------------------------------------
163 PsiBlast_CBE 83.2858%-128 - C5 -2POG B:[4-225] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSE----------SMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLESAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKSVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTF--STLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSM-----------------------------------------------------------------------------------
205 PsiBlast_CBE 83.0856%-138 - C5 -2JF9 ESR1_HUMAN B:[24-248] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SLALS-LTADQMVSALLDAEPPILYSEYD--------SMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYT--------LEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMK----------------------------------------------------------------------------------
182 PsiBlast_CBE 82.6358%-125 - C5 -2I0J ESR1_HUMAN A:[4-225] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLESAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKSVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTF--STLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSM-----------------------------------------------------------------------------------
180 PsiBlast_CBE 82.5658%-124 - C5 -2I0J ESR1_HUMAN C:[4-225] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLESAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKSVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSM-----------------------------------------------------------------------------------
161 PsiBlast_CBE 82.2058%-128 - C5 -2Q70 B:[4-225] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALS-LTADQMVSALLDAEPPILYSE----------SMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLESAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKSVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTF--STLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSM-----------------------------------------------------------------------------------
203 PsiBlast_CBE 82.1956%-125 - C5 -2JFA ESR1_HUMAN A:[24-248] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SLALS-LTADQMVSALLDAEPPILYSEY----PFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK----LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRF-RMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMK----------------------------------------------------------------------------------
233 Fugue 80.0051%-114 - C5 -3ERT A:[13-258] ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LALSLTADQMVSALLDAEPP----------------------ILY-SEYDP-------TRPFS------------EASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSME--HPGKLLFA--PNLLLDRNQGKCVEGMVEIFDMLLATSSRFR-MMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKC----KNVVPLYDLLLEMLD--------AHRLHAP-----------------------------------------------