@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Wbm0089: (2015-11-28 )
MKMVKGILCDWLGVTELQESQKIDAEQFQRIFSALKKWQEAQKVNTEQFEKVFSALEEKIGTEQFQSMQEYLNGLQKKFTGLEEKAGTLIETVGEQEKIMLTCCIIASVITLAAISFITFCIYQGVKSGRERQRSLSDISAQNLMNQTHQAQNFM
Atome Classification :
(20 SA)
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------.........10........20..-......30......-..40.-----------.---------......50...-------....-.60....--....70.....-...80........90.........100......-.110...-..-...120.......130-....-...140.....----..150...-------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------M
K
M
V
K
G
I
L
C
DWL
G
V
T
E
L
Q
E
SQKI-
D
A
E
Q
F
Q
R
I
F
S
A
L
K
K
-
W
Q
E
A
Q-----------K---------V
N
T
E
Q
F
E
K
V
F
S
-------
A
L
E
E
-KI
G
T
E
Q
F
--
Q
S
M
Q
E
Y
L
N
G
L
Q
-
K
K
FT
G
L
E
E
K
A
G
T
L
I
-
E
TVGEQ
E
K
I
M
L
T
C
C
I
I
A
S
-
V
I
-
T
L
A
A
-
I
S
-
F
I
T
F
C
I
Y
Q
G
V
KS
G
R
E
R
-
Q
R
S
L
-
S
D
I
S
A
Q
N
L
M
N
Q
----
T
H
Q
AQNFM-------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
77.96
20%
-50
- C5 -
4TKO
-
?
B:
[120-236]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
K
L
V
K
L
D
W
E
R
Y
K
S
L
F
Q
K
G
L
I
-
P
R
R
K
F
E
E
V
D
T
N
L
K
V
-
L
L
H
E
R
-----------
E
---------
Y
L
E
K
S
I
Q
E
I
N
T
-------
E
I
K
R
A
K
K
G
I
E
N
A
--
R
N
E
F
K
T
I
E
E
L
K
-
K
E
L
S
S
L
E
E
E
I
K
S
L
K
-
E
R
I
K
T
A
E
Q
K
I
K
D
T
V
L
I
A
P
-
F
D
-
G
V
V
A
-
K
R
-
F
I
S
R
G
D
V
V
R
A
G
Q
P
A
F
A
-
L
V
N
P
-
E
S
F
Y
V
E
V
L
L
E
E
----
T
K
L
K
G
V
K
V
-------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
Fugue
73.98
16%
-34
- C4 -
2JRF
-
TPPP3_HUMAN
A:
[1-178]
--------------------------------------------------------------------------------------------------------------------------------------------MAASTDI
A
G
L
E
E
S
F
R
K
F
A
I
H
GDPKASG
Q
E
M
N
G
K
N
W
A
K
L
C
K
D
C
K
V
A
D
G
K
S
V
-
T
G
T
D
V
D
I
V
F
S
K
V
K
G
--
K
S
A
R
-----------
V
---------
I
N
Y
E
E
F
K
K
A
L
E
-------
E
L
A
T
-
K
R
F
K
G
K
----
S
K
E
E
A
F
D
A
I
C
-
Q
L
V
A
G
K
E
P
A
N
V
G
V
T
-
K
A
K
T
G
G
A
V
D
R
L
T
---
D
T
S
-
R
Y
-
T
G
S
H
-
K
E
-
R
F
D
E
S
G
K
G
K
G
I
A
G
R
Q
D
-
I
L
D
D
-
S
G
Y
V
S
A
Y
K
N
A
G
----
T
Y
D
A
K
V
K
K
LE-----------------------------------------------------------------------------------------------------------------------------------------------------------------
14
HHSearch
68.43
14%
-19
- C5 -
3PUR
-
KDM7_CAEEL
A:
[467-523]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
T
A
S
Q
I
M
K
A
E
M
E
R
-
W
M
D
R
E
-----------
L
R
LGPEKNAI
L
P
T
D
D
K
N
K
I
M
I
-------
S
V
R
K
-
Q
I
E
I
Q
T
----
K
I
Q
N
A
K
N
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34
Fugue
65.66
13%
-49
- C3 -
2G3V
1
CAGS_HELPY
A:
[22-182]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
L
I
E
S
L
Q
E
N
E
L
L
-
N
T
D
E
K
K
K
I
I
D
Q
I
K
T
M
H
D
F
F
K
-----------
Q
M
H
-------
T
N
K
G
A
L
D
K
V
L
R
N
YMKD
Y
R
A
V
I
K
-
S
I
G
V
D
K
F
--
K
K
V
Y
R
L
L
E
S
E
T
M
E
L
L
H
A
I
A
E
N
P
N
F
L
F
S
K
F
D
R
S
I
L
G
I
F
L
P
F
F
S
K
P
I
M
F
K
M
S
I
R
E
M
D
S
-
Q
I
E
L
Y
G
T
K
L
P
L
L
K
L
F
V
M
T
D
E
E
M
N
F
Y
A
N
L
K
T
I
E
Q
----
Y
N
D
Y
V
R
D
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
HHSearch
63.31
22%
-44
- C5 -
3UMH
6
A:
[34-89]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
R
E
R
M
S
Q
V
M
R
E
-
W
E
E
A
E
R
Q
A
K
NLP
K
A
D
K
K
---------
A
V
I
Q
H
F
Q
E
K
V
E
-------
S
L
E
Q
-
E
A
A
N
E
R
Q
--
Q
L
V
E
T
H
M
A
R
V
E
-
A
M
L
N
D
R
R
R
L
A
L
E
N
Y
-
I
T
A
L
Q
A
V
P
P
R
P
R
H
V
F
N
M
L
-
K
K
-
Y
V
R
A
-
E
Q
-
K
D
R
Q
H
T
L
K
H
F
E
H
V
R
M
V
-
D
P
K
K
-
A
A
Q
I
R
S
Q
V
M
T
H
----
L
R
V
I
Y
E
R
M
-------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
Fugue
61.93
19%
29
- C3 -
2GTS
-
?
A:
[4-80]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
Q
M
D
T
E
E
V
R
E
F
V
G
H
L
E
R
-
F
K
E
L
L
-----------
R
---------
E
E
V
N
S
L
S
N
H
F
H
-------
N
L
E
S
--
W
R
D
A
R
R
--
D
K
F
S
E
V
L
D
N
L
K
-
S
T
F
N
E
F
D
E
A
A
Q
E
Q
I
-
A
W
L
K
E
R
I
R
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
Fugue
58.80
9%
-39
* C4 *
3DSK
5
CP74A_ARATH
A:
[24-489]
D
L
P
I
R
N
IPGNYGLP
I
V
G
P
I
K
D
R
W
D
Y
F
YDQG
A
E
E
F
F
K
S
R
I
R
K
Y
NST
V
Y
R
V
N
M
P
PGAFIAENP
Q
V
V
A
L
L
D
G
K
S
F
P
VLFDVDKVEKKDLLTGTYMPSTELTGGYRILSYLDPSE
P
K
H
E
K
L
K
N
L
L
F
F
L
L
K
S
S
R
NR
I
F
P
E
F
Q
A
T
Y
S
E
L
F
D
S
L
E
K
E
L
S
L
KG
K
A
D
F
G
G
S
S
D
G
T
A
F
N
F
L
A
R
A
F
Y
G
-
T
N
P
A
D
T
K
L
K
A
D
A
-
P
G
L
I
T
K
W
V
L
F
N
L
H
P
L
L
S
I
G
L
-----------
P
---------
R
V
I
E
E
P
L
I
H
T
F
-------
S
L
P
P
-
A
L
V
K
S
D
Y
--
Q
R
L
Y
E
F
F
L
E
S
A
-
G
E
I
L
V
E
A
D
K
L
G
I
-------
S
R
E
E
A
T
H
N
L
L
F
A
T
C
-
F
N
-
T
W
G
G
-
M
K
I
L
F
P
N
M
V
K
R
I
G
R
A
G
H
Q
V
-
H
N
R
L
-
A
E
E
I
R
S
V
I
K
S
N
GGEL
T
M
G
A
I
E
K
M
E
L
T
K
S
V
V
Y
E
C
L
R
F
EPPVT
A
Q
Y
G
R
AK
K
D
L
V
I
E
S
HD
A
A
F
K
V
K
AG
E
M
L
Y
G
Y
Q
P
L
A
T
R
DPKIFDRADEFVPERFVG
E
E
G
E
K
L
LRHVLWSNGPET
E
T
P
T
VGNKQCAG
K
D
F
V
V
L
V
A
R
L
F
V
I
E
I
F
R
R
Y
D
S
F
D
I
E
V
G
T
S
PL
G
S
S
V
N
F
S
S
L
R
K
A------------------
18
HHSearch
49.86
20%
92
- C5 -
3ONT
-
THRSP_MOUSE
A:
[117-141]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
H
L
H
F
C
S
L
H
-
H
I
L
T
H
L
T
R
K
A
Q
E
V
T
-
R
K
Y
Q
E
M
T
G
Q
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
49.10
34%
57
- C5 -
4XDZ
2
?
A:
[280-325]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
-
R
I
R
S
G
E
F
A
R
E
W
I
K
E
Y
E
R
G
M
P
-
T
V
F
K
E
L
S
E
L
E
G
S
T
I
-
E
T
V
G
R
K
L
R
E
M
M
F
R
G
M
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
38
Fugue
46.77
12%
23
* C3 *
2GUT
-
MED15_HUMAN
A:
[2-78]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
A
M
G
Q
E
T
D
W
R
S
T
A
F
-
R
Q
K
L
V
S
Q
I
E
D
A
M
R
K
-
A
G
V
A
H
-----------
S
---------
K
S
S
K
D
M
E
S
--
H
-------
V
F
L
K
-
A
K
T
R
D
E
Y
--
L
S
L
V
A
R
L
I
I
H
F
-
R
D
I
H
N
K
K
S
Q
A
S
V
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_CBE
46.04
34%
64
- C5 -
4XDZ
1
?
B:
[280-325]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
-
R
I
R
S
G
E
F
AR
E
W
I
K
E
Y
E
R
G
M
P
-
T
V
F
K
E
L
S
E
L
E
G
S
T
I
-
E
T
V
G
R
K
L
R
E
M
M
F
R
G
M
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
46.01
34%
60
- C5 -
4XEH
-
?
A:
[280-325]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
-
R
I
R
S
G
E
F
A
R
E
W
I
K
E
Y
E
R
G
M
P
-
T
V
F
K
E
L
S
E
L
E
G
S
T
I
-
E
T
V
G
R
K
L
R
E
M
M
F
R
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
45.19
25%
74
- C5 -
3HD0
-
NFI_THEMA
A:
[1-57]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
D
Y
R
Q
L
H
R
-
W
D
------------------------
L
P
P
E
E
A
I
K
V
Q
N
-------
E
L
R
K
-
K
I
K
L
T
P
Y
--
E
G
E
P
E
Y
V
A
G
V
D
-
L
S
F
P
G
K
E
E
G
L
A
V
I
V
-
V
L
E
Y
P
S
F
K
I
L
E
V
V
S
E
R
G
E
-
I
T
-
F
P
Y
I
-
P
G
-
L
L
A
F
R
E
G
P
L
F
L
K
A
W
E
K
-
L
R
T
K
-
P
D
V
V
V
F
D
G
Q
G
L
----
A
H
P
R
K
L
G
I
-------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
HHSearch
44.07
17%
80
- C5 -
3EFG
1
SLYX_XANCP
A:
[10-45]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
E
L
E
A
R
L
V
E
L
E
-
T
R
L
S
F
Q
E
Q
A
L
T
E
L
S
-
E
A
L
A
D
A
R
L
T
G
A
R
N
A
E
L
I
R
-
H
L
-
L
E
D
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
Fugue
43.94
10%
49
- C3 -
1J5S
-
UXAC_THEMA
A:
[0-450]
-------------------------HMFLGEDYLLTN
R
A
A
V
R
L
F
N
E
VKDL
P
I
V
D
PHNHLD
A
K
D
I
V
E
NKPWNDIWEVEGATD
H
Y
V
W
E
L
M
R
R
C
GVSEEYITGSRS
N
K
E
K
W
L
A
L
A
K
V
FPRFVGN
P
T
Y
E
W
I
H
L
D
L
W
R
R
FNIK
K
V
I
S
EET
A
E
E
I
W
E
E
T
K
K
K
LPEMT
P
Q
K
L
L
R
D
M
K
V
E
I
L
C
T
T
D
D
P
V
S
T
L
E
H
H
R
K
A
-
K
E
A
V
E
G
V
T
I
L
P
T
W
R
-
P
D
R
A
M
-----------
N
---------
V
D
K
E
G
W
R
E
Y
V
E
-------
K
M
G
E
-
R
Y
G
E
D
-
T
--
S
T
L
D
G
F
L
N
A
L
W
-
K
S
H
E
H
F
K
E
H
G
C
V
A
S
-
D
H
A
L
L
E
--------
P
S
V
Y
-
Y
V
-
D
E
N
R
-
A
R
-
A
V
H
E
K
A
F
S
G
E
K
L
T
Q
D
E
-
I
N
D
Y
-
K
A
F
M
M
V
Q
F
G
K
M
----
N
Q
E
T
N
W
V
T
Q
L
H
I
G
ALRDYR
D
S
L
F
K
T
LGPDSGG
D
I
S
T
NFLRIAEGL
R
Y
F
L
N
E
F
DGK
L
K
I
V
L
Y
V
LDPTH
L
P
T
I
S
T
I
A
R
A
F
PN
V
Y
V
G
A
PWWFNDS
P
F
G
M
E
M
H
L
K
Y
L
A
S
V
DLLYNLAGMVTDSRKLLS
F
G
S
R
T
E
M
F
R
R
V
L
S
N
V
V
G
E
M
V
E
K
GQIP
I
K
E
A
R
E
L
V
K
H
V
S
Y
D
G
P
K
A
L
F
F
1
PsiBlast_PDB
43.30
34%
-1
- C5 -
3TQI
-
GUAA_COXBU
A:
[300-329]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
I
S
D
P
E
E
K
R
K
I
-
A
G
E
Q
F
I
R
V
F
E
------
E
Q
A
K
-----------
K
---------
L
N
V
K
W
L
G
Q
G
T
I
-------
Y
P
D
V
-
I
E
S
K
L
I
E
--
P
L
R
E
L
F
K
D
E
V
R
-
K
L
G
L
E
L
G
L
P
A
D
L
I
Y
-
R
H
P
F
P
G
P
G
L
A
I
R
I
L
G
E
V
S
-
A
E
-
Y
I
N
I
-
L
K
-
Q
A
D
A
I
F
I
E
E
L
K
K
S
D
Y
Y
-
H
Q
V
S
-
Q
A
F
A
V
F
M
P
L
K
S
----
V
Y
G
Y
I
I
A
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
HHSearch
42.15
21%
100
- C5 -
3A2A
-
HVCN1_HUMAN
A:
[11-41]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
Q
L
L
R
L
K
-
Q
M
N
V
Q
L
A
A
K
I
Q
H
L
E
-
F
S
C
S
E
K
E
Q
E
I
E
R
L
N
K
L
L
R
-
Q
H
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
HHSearch
38.49
29%
68
- C5 -
1PEH
1
A:
[7-33]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
Q
E
R
V
D
K
V
K
-
K
K
V
K
D
V
E
E
K
S
K
E
W
V
-
Q
K
V
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
38.46
32%
113
- C5 -
2PNV
-
KCNN2_RAT
A:
[498-522]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
E
R
S
E
D
F
E
-
K
R
I
V
T
L
E
T
K
L
E
T
L
I
-
G
S
I
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
37.94
35%
29
- C5 -
2YJG
-
?
A:
[20-61]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
R
I
Q
G
I
L
R
S
-
K
---------------------------
M
S
E
E
D
I
V
K
R
-------
A
L
E
N
-
P
I
G
T
K
R
L
--
Q
D
L
A
E
G
K
K
N
I
V
-
I
I
T
S
D
H
T
R
P
V
P
S
R
I
-
T
L
P
L
L
L
D
E
I
R
K
K
N
K
S
A
N
V
-
K
I
-
L
I
A
T
-
G
F
-
H
R
G
T
T
L
Q
E
M
K
A
K
F
G
E
D
-
L
V
E
N
-
E
Q
F
V
V
H
D
S
R
N
S
----
E
N
M
E
L
I
G
T
-------------------------------------------------------------------------------------------------------------------------------------------------------------------