@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Wbm0107: (2015-11-28 )
MAHIPVLLKEMLLQLSPQNGGIYVDATFGAGGYSKAILESADCKVYAIDRDKTVIKFYEDLNIKYPSRVKLFIEKFSNIRSILDSNSLEYLVEPSAVSKLSSIISSGIQKKNIWISASSTGVTPSNTVDGVVFDIGVSSMQLDDGDRGFSFLHDGPLDMRMDNSSHTNASTFVNALREEEIANTIYNYGGERHSRRIARAIVNARKKKTIKTTFELANIVRSVVFRGKSKIDPATRTFQAIRIWVNDELGELEKGIKAASEILNKNGKLIVVTFHSLEDRIVKTFFKSLCEPRSIDCKVFSLLNKKMIKASAEEVNANPRSRSAKLRAIQRLS
Atome Classification :
(20 SA)
---------------------......-.-..10.------.......20........30---------........--40.--.--.......-50........60...------..--...70....-----....80.....--...90........100.......110.......120...--------....130.-......140.......--150......-.-160..--.....170......-----.180.......190.-..----.....200....--------...210....--...220.-----.-...---..230.......240..-------------------.....250.......260.--......270.......280.......290.......300...-----....310----.........320.......330.-
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
---------------------MA
H
I
P
V
-
L
-
L
K
E
M
L
------
L
QLSPQNG
G
I
Y
V
D
A
T
FGAG---------G
Y
S
K
A
I
LE--S-A--D--
C
K
V
Y
A
ID-RD
K
T
V
I
K
F
Y
E
DLNIK------Y
P
--
S
R
V
K
L
F
I
E
K
-----
F
S
N
I
R
S
I
L
DSN--S
L
E
Y
L
VE
P
S
A
V
S
K
L
S
S
I
I
S
SGIQKK
N
I
W
I
SASSTGVTPS--------NTV
D
G
V
V
F
-
D
IGV
S
S
M
QLDDGDRG
F
--
S
FLHDGPL
D
-
M
-RMDNS--SHT
N
A
S
T
F
V
N
A
L
R
E
-----
E
E
I
A
N
T
I
Y
NYGG
E
-
R
-
H
S
----
R
R
I
A
R
A
I
V
N
A
RK--------KK
T
I
K
T
T
F
E
L
--
A
N
I
V
R
S
V
-----
V
-FRG---KSKIDPAT
R
T
F
Q
A
I
R
I
W
-------------------VN
D
E
L
G
E
L
E
K
G
I
K
A
A
S
E
I
L
--NKNG
K
L
I
V
V
T
F
H
S
L
E
D
R
I
V
K
T
F
F
K
S
LCEPRSI
D
C
K
V
F
S
L
L
N
K
-----
K
M
I
K
A
------
S
A
E
EVNANPRS
R
S
A
K
L
R
A
I
QRLS-
22
HHSearch
95.98
42%
-86
- C6 -
1M6Y
2
RSMH_THEMA
A:
[8-296]
---------------------
Q
R
H
I
P
V
-
M
-
V
R
E
V
I
------
E
F
L
K
P
E
D
E
K
I
I
L
D
C
T
V
G
E
G
---------
G
H
S
R
A
I
L
E
--
H
-
C
--
P
G-
C
R
I
I
G
I
D
-
V
D
S
E
V
L
R
I
A
E
E
K
L
K
E
------
F
S
--
D
R
V
S
L
F
K
V
S
-----
Y
R
E
A
D
F
L
L
K
T
L
--
G
-------------------------------------
I
--------
E
K
V
D
G
I
L
M
-
D
L
G
V
S
T
Y
Q
L
K
G
E
N
R
G
F
--
T
F
E
R
E
E
P
L
D
-
M
-
R
M
D
L
E
--
S
E
V
T
A
Q
K
V
L
N
E
L
P
E
-----
E
E
L
A
R
I
I
F
E
Y
G
E
E
-
K
R
F
A
----
R
R
I
A
R
K
I
V
E
N
R
-----------
P
L
N
T
T
L
D
L
--
V
K
A
V
R
E
A
-----
L
-
P
S
Y
E
I
R
R
R
K
R
H
F
A
T
K
T
F
Q
A
I
R
I
Y
-------------------
V
N
R
E
L
E
N
L
K
E
F
L
K
K
A
E
D
L
L
--
N
P
G
G
R
I
V
V
I
S
F
H
S
L
E
D
R
I
V
K
E
T
F
R
N
S
K
--------
K
L
R
I
L
T
E
-----
K
P
V
R
P
------
S
E
E
E
I
R
E
N
P
R
A
R
S
G
R
L
R
A
A
E
R
I
--
23
HHSearch
95.19
43%
-91
- C6 -
1WG8
1
RSMH_THET8
A:
[4-283]
---------------------
M
T
H
V
P
V
-
L
-
Y
Q
E
A
L
------
D
L
L
A
V
R
P
G
G
V
Y
V
D
A
T
L
G
G
A
---------
G
H
A
R
G
I
L
E
--
R
----
G
--
G
R
V
I
G
L
D
-
Q
D
P
E
A
V
A
R
A
K
G
L
H
L
-----------
P
G
L
T
V
V
Q
G
N
-----
F
R
H
L
K
R
H
L
A
A
L
--
G
----------------------------------
V
-----------
E
R
V
D
G
I
L
A
-
D
L
G
V
S
S
F
H
L
D
D
P
S
R
G
F
--
S
Y
Q
K
E
G
P
L
D
-
M
-
R
M
G
L
E
--
G
-
P
T
A
K
E
V
V
N
R
L
P
L
-----
E
A
L
A
R
L
L
R
E
L
G
E
E
-
P
-
Q
A
----
Y
R
I
A
R
A
I
V
A
A
R
E
--------
K
A
P
I
E
T
T
T
Q
L
--
A
E
I
V
R
K
A
-----
V
-
G
F
R
----
R
A
G
H
P
A
R
K
T
F
Q
A
L
R
I
Y
-------------------
V
N
D
E
L
N
A
L
K
E
F
L
E
Q
A
A
E
V
L
--
A
P
G
G
R
L
V
V
I
A
F
H
S
L
E
D
R
V
V
K
R
F
L
R
E
S
G
---------
L
K
V
L
T
K
-----
K
P
L
V
P
------
S
E
K
E
A
A
Q
N
P
R
A
R
S
A
K
L
R
A
A
E
K
E
A
-
21
HHSearch
94.98
40%
-85
* C6 *
3TKA
8
RSMH_ECOLI
A:
[42-346]
------------------------
T
T
V
-
L
-
L
D
E
A
V
------
N
G
L
N
I
R
P
D
G
I
Y
I
D
G
T
F
G
R
G
---------
G
H
S
R
L
I
L
S
--
Q
-
L
G-
E
E-
G
R
L
L
A
I
D
-
R
D
P
Q
A
I
A
V
A
K
T
I
D
D
-----------
P
R
F
S
I
I
H
G
P
-----
F
S
A
L
G
E
Y
V
A
E
R
--
D
----------------------------------
L
--
I
--------
G
K
I
D
G
I
L
L
-
D
L
G
V
S
S
P
Q
L
D
D
A
E
R
G
F
--
S
F
M
R
D
G
P
L
D
-
M
-
R
M
D
P
T
--
R
G
Q
S
A
A
E
W
L
Q
T
A
E
E
-----
A
D
I
A
W
V
L
K
T
Y
G
E
E
-
R
-
F
A
----
K
R
I
A
R
A
I
V
E
R
N
R
--------
E
Q
P
M
T
R
T
K
E
L
--
A
E
V
V
A
A
A
-----
T
-
P
V
K
-------
H
P
A
T
R
T
F
Q
A
V
R
I
W
-------------------
V
N
S
E
L
E
E
I
E
Q
A
L
K
S
S
L
N
V
L
--
A
P
G
G
R
L
S
I
I
S
F
H
S
L
E
D
R
I
V
K
R
F
M
R
E
N
S
R
G
-------
R
Q
L
R
A
L
-----
G
K
L
M
P
------
G
E
E
E
V
A
E
N
P
R
A
R
S
S
V
L
R
I
A
E
R
T
N
-
3
PsiBlast_PDB
93.57
36%
-89
- C6 -
1M6Y
2
RSMH_THEMA
A:
[10-296]
-----------------------
H
I
P
V
-
M
-
V
R
E
V
I
------
E
F
L
K
P
E
D
E
K
I
I
L
D
C
T
V
G
E
G
---------
G
H
S
R
A
I
L
E
--
H
-
C
--
P
G-
C
R
I
I
G
I
D
-
V
D
S
E
V
L
R
I
A
E
E
K
L
K
E
------
F
S
--
D
R
V
S
L
F
K
V
S
-----
Y
R
E
A
D
F
L
L
K
T
----------------------
L
G
I
E
K
-------------------------
V
D
G
I
L
M
-
D
L
G
V
S
T
Y
Q
L
K
G
E
N
R
G
F
--
T
F
E
R
E
E
P
L
D
-
M
-
R
M
D
L
E
--
S
E
V
T
A
Q
K
V
L
N
E
L
P
E
-----
E
E
L
A
R
I
I
F
E
Y
G
E
E
K
R
-
F
A
----
R
R
I
A
R
K
I
V
E
N
R
-----------
P
L
N
T
T
L
D
L
--
V
K
A
V
R
E
A
L
P
S
Y
E
I
-
R
R
R
---
K
R
H
F
--
A
T
K
T
F
Q
A
I
R
I
Y
-------------------
V
N
R
E
L
E
N
L
K
E
F
L
K
K
A
E
D
L
L
--
N
P
G
G
R
I
V
V
I
S
F
H
S
L
E
D
R
I
V
K
E
T
F
R
--------
N
S
K
K
L
R
I
L
T
E
-----
K
P
V
R
P
------
S
E
E
E
I
R
E
N
P
R
A
R
S
G
R
L
R
A
A
E
R
I
--
4
PsiBlast_PDB
93.33
36%
-87
- C6 -
1N2X
2
RSMH_THEMA
A:
[10-296]
-----------------------
H
I
P
V
-
M
-
V
R
E
V
I
------
E
F
L
K
P
E
D
E
K
I
I
L
D
C
T
V
G
E
G
---------
G
H
S
R
A
I
L
E
--
H
-
C
--
P
G-
C
R
I
I
G
I
D
-
V
D
S
E
V
L
R
I
A
E
E
K
L
K
E
------
F
S
--
D
R
V
S
L
F
K
V
S
-----
Y
R
E
A
D
F
L
L
K
T
----------------------
L
G
I
E
K
-------------------------
V
D
G
I
L
M
-
D
L
G
V
S
T
Y
Q
L
K
G
E
N
R
G
F
--
T
F
E
R
E
E
P
L
D
-
M
-
R
M
D
L
E
--
S
E
V
T
A
Q
K
V
L
N
E
L
P
E
-----
E
E
L
A
R
I
I
F
E
Y
G
E
E
K
R
-
F
A
----
R
R
I
A
R
K
I
V
E
N
R
-----------
P
L
N
T
T
L
D
L
--
V
K
A
V
R
E
A
L
P
S
Y
E
I
-
R
R
R
---
K
R
H
F
--
A
T
K
T
F
Q
A
I
R
I
Y
-------------------
V
N
R
E
L
E
N
L
K
E
F
L
K
K
A
E
D
L
L
--
N
P
G
G
R
I
V
V
I
S
F
H
S
L
E
D
R
I
V
K
E
T
F
R
--------
N
S
K
K
L
R
I
L
T
E
-----
K
P
V
R
P
------
S
E
E
E
I
R
E
N
P
R
A
R
S
G
R
L
R
A
A
E
R
I
--
2
PsiBlast_PDB
92.95
35%
-89
- C6 -
3TKA
8
RSMH_ECOLI
A:
[42-344]
------------------------
T
T
V
-
L
-
L
D
E
A
V
------
N
G
L
N
I
R
P
D
G
I
Y
I
D
G
T
F
G
R
G
---------
G
H
S
R
L
I
L
S
Q
L
G
-
E
--
E
--
G
R
L
L
A
I
D
-
R
D
P
Q
A
I
A
V
A
K
T
I
D
---------
D
--
P
R
F
S
I
I
H
G
P
-----
F
S
A
L
G
----------
E
Y
V
A
E
R
D
L
I
G
K
------------------------------------
I
D
G
I
L
L
-
D
L
G
V
S
S
P
Q
L
D
D
A
E
R
G
F
--
S
F
M
R
D
G
P
L
D
-
M
-
R
M
D
P
T
--
R
G
Q
S
A
A
E
W
L
Q
T
A
E
E
-----
A
D
I
A
W
V
L
K
T
Y
G
E
E
-
R
-
F
A
----
K
R
I
A
R
A
I
V
E
R
N
R
--------
E
Q
P
M
T
R
T
K
E
L
--
A
E
V
V
A
A
A
-----
T
-
P
V
K
-------
H
P
A
T
R
T
F
Q
A
V
R
I
W
-------------------
V
N
S
E
L
E
E
I
E
Q
A
L
K
S
S
L
N
V
L
--
A
P
G
G
R
L
S
I
I
S
F
H
S
L
E
D
R
I
V
K
R
F
M
R
E
N
S
R
G
------------------
R
Q
L
R
A
L
G
K
L
M
P
G
E
E
E
V
A
E
N
P
R
A
R
S
S
V
L
R
I
A
E
R
T
N
-
19
PsiBlast_CBE
92.72
39%
-90
- C6 -
1WG8
1
RSMH_THET8
B:
[5-282]
----------------------
T
H
V
P
V
-
L
-
Y
Q
E
A
L
------
D
L
L
A
V
R
P
G
G
V
Y
V
D
A
T
L
G
G
A
---------
G
H
A
R
G
I
L
E
--
R
-
G
-----
G
R
V
I
G
L
D
-
Q
D
P
E
A
V
A
R
A
K
G
L
H
L
P
------
G
L
--
T
V
V
Q
-----------
G
N
F
R
H
L
-----------------------------
K
R
H
L
----
A
A
L
G
V
-----------
E
R
V
D
G
I
L
A
-
D
L
G
V
S
S
F
H
L
D
D
P
S
R
G
F
--
S
Y
Q
K
E
G
P
L
D
-
M
-
R
M
G
L
E
--
G
P
T
-
A
K
E
V
V
N
R
L
P
L
-----
E
A
L
A
R
L
L
R
E
L
G
E
E
-
P
-
Q
A
----
Y
R
I
A
R
A
I
V
A
A
R
E
--------
K
A
P
I
E
T
T
T
Q
L
--
A
E
I
V
R
K
A
-----
V
G
F
R
R
---
A
G
--
H
P
A
R
K
T
F
Q
A
L
R
I
Y
-------------------
V
N
D
E
L
N
A
L
K
E
F
L
E
Q
A
A
E
V
L
--
A
P
G
G
R
L
V
V
I
A
F
H
S
L
E
D
R
V
V
K
R
F
L
------
R
E
S
G
L
K
V
---
L
T
K
-----
K
P
L
V
P
------
S
E
K
E
A
A
Q
N
P
R
A
R
S
A
K
L
R
A
A
E
K
E
A
-
1
PsiBlast_PDB
90.51
39%
-84
- C6 -
1WG8
1
RSMH_THET8
A:
[4-282]
---------------------
M
T
H
V
P
V
-
L
-
Y
Q
E
A
L
------
D
L
L
A
V
R
P
G
G
V
Y
V
D
A
T
L
G
G
A
---------
G
H
A
R
G
I
L
E
--
R
-
G
-----
G
R
V
I
G
L
D
-
Q
D
P
E
A
V
A
R
A
K
G
L
H
L
P
------
G
L
--
T
V
V
Q
-----------
G
N
F
R
H
L
-----------------------------
K
R
H
L
----
A
A
L
G
V
-----------
E
R
V
D
G
I
L
A
-
D
L
G
V
S
S
F
H
L
D
D
P
S
R
G
F
--
S
Y
Q
K
E
G
P
L
D
-
M
-
R
M
G
L
E
--
G
P
T
-
A
K
E
V
V
N
R
L
P
L
-----
E
A
L
A
R
L
L
R
E
L
G
E
E
-
P
-
Q
A
----
Y
R
I
A
R
A
I
V
A
A
R
E
--------
K
A
P
I
E
T
T
T
Q
L
--
A
E
I
V
R
K
A
-----
V
G
F
R
R
---
A
G
--
H
P
A
R
K
T
F
Q
A
L
R
I
Y
-------------------
V
N
D
E
L
N
A
L
K
E
F
L
E
Q
A
A
E
V
L
--
A
P
G
G
R
L
V
V
I
A
F
H
S
L
E
D
R
V
V
K
R
F
L
------
R
E
S
G
L
K
V
---
L
T
K
-----
K
P
L
V
P
------
S
E
K
E
A
A
Q
N
P
R
A
R
S
A
K
L
R
A
A
E
K
E
A
-
41
Fugue
89.74
39%
-70
- C6 -
1M6Y
2
RSMH_THEMA
A:
[4-296]
-----------------RKYS
Q
R
H
I
P
V
M
V
--
R
E
V
I
------
E
F
L
K
P
E
D
E
K
I
I
L
D
C
T
V
G
E
G
---------
G
H
S
R
A
I
L
E
--
H
C
P
--
G
--
C
R
I
I
G
I
D
-
V
D
S
E
V
L
R
I
A
E
E
K
L
K
E
------
F
S
--
D
R
V
S
L
F
K
V
S
-----
Y
R
E
A
D
F
L
L
K
T
L
--
G
I
E
K
----------------------------------------------
V
D
G
I
L
M
D
L
G
V
S
T
Y
Q
L
K
G
E
N
R
G
F
--
T
F
E
R
E
E
P
L
D
M
R
M
D
L
E
S
E
----
V
T
A
Q
K
V
L
N
E
L
P
E
-----
E
E
L
A
R
I
I
F
E
Y
G
E
E
K
R
-
F
A
----
R
R
I
A
R
K
I
V
E
N
R
P
--------
L
N
T
T
L
D
L
V
K
A
--
V
R
E
A
L
P
S
-----
Y
-
E
I
R
---
R
R
K
R
H
F
A
T
K
T
F
Q
A
I
R
I
Y
-------------------
V
N
R
E
L
E
N
L
K
E
F
L
K
K
A
E
D
L
L
--
N
P
G
G
R
I
V
V
I
S
F
H
S
L
E
D
R
I
V
K
E
T
F
R
N
S
--------
K
K
L
R
I
L
T
E
-----
K
P
V
R
P
------
S
E
E
E
I
R
E
N
P
R
A
R
S
G
R
L
R
A
A
E
R
I
--
42
Fugue
58.54
22%
-68
- C6 -
4PON
-
?
A:
[7-197]
---------------------
M
I
L
K
K
I
-
L
P
Y
S
K
E
L
------
L
K
M
A
A
G
E
G
D
I
V
I
D
A
T
M
G
N
G
---------
H
D
T
Q
F
L
A
E
--
L
-
V
GE
N
--
G
H
V
Y
A
F
D
I
Q
E
S
A
V
A
N
T
K
E
R
L
G
E
A
------
Y
Q
--
A
R
T
T
L
F
H
K
S
-----
H
D
K
I
A
K
S
L
P
P
E
--
T
-------------------------------------
H
--------
G
K
V
A
A
A
V
F
-
N
L
G
N
G
S
S
T
I
K
A
I
E
Q
L
L
--
S
I
M
K
D
E
G
L
I
-
V
-
L
V
V
Y
H
--
G
N
-
D
V
L
D
F
C
R
N
L
D
Q
-----
Q
A
A
R
V
L
T
Y
G
F
I
N
Q
-
Q
-
N
D
----
P
P
F
I
V
A
I
E
K
K
A
Q
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
45.76
31%
-68
- C6 -
4PON
-
?
A:
[7-82]
--------------------------
M
-
I
-
L
K
K
I
L
P
Y
S
K
E
L
L
K
M
A
A
G
E
G
D
I
V
I
D
A
T
M
G
N
G
---------
H
D
T
Q
F
L
A
E
L
V
G
-
E
--
N
--
G
H
V
Y
A
F
D
I
Q
E
S
A
V
A
N
T
K
E
R
L
G
E
A
------
Y
Q
--
A
R
T
T
L
F
H
K
S
-----
H
D
K
I
A
K
S
L
P
P
E
--
T
H
G
K
V
A
A
A
V
F
N
L
G
N
G
S
S
T
I
K
A
I
E
Q
L
L
S
I
M
K
D
E
G
L
I
V
L
V
V
--------
Y
H
G
N
D
V
L
D
-
F
C
R
N
L
D
Q
Q
A
A
R
V
L
T
Y
G
--
F
I
N
Q
Q
N
D
P
P
-
F
-
I
V
A
I
E
--
K
K
A
Q
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
40
HHSearch
45.14
22%
-55
- C6 -
3EEY
1
?
A:
[20-86]
---------------------------------------------
V
K
E
G
D
T
V
V
D
A
T
C
G
N
G
---------
N
D
T
A
F
L
A
S
--
L
-
V
G-
E
N-
G
R
V
F
G
F
D
-
I
Q
D
K
A
I
A
N
T
T
K
K
L
T
D
------
L
N
LI
D
R
V
T
L
I
K
D
G
-----
H
Q
N
M
D
K
Y
I
D
C
P
--
V
K
A
V
M
F
N
L
G
Y
L
P
S
G
D
H
S
I
S
T
R
P
E
T
T
I
Q
A
L
S
K
A
M
E
L
L
V
T
G
--------
G
I
I
T
V
V
I
Y
-
Y
G
G
D
T
G
F
E
E
K
E
K
V
L
E
F
--
L
K
G
V
D
Q
K
K
F
-
I
-
V
Q
R
T
D
--
F
I
N
Q
A
N
C
P
P
I
L
V
C
I
-----
E
K
I
S
E
G
H
H
H
H
H
H
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
43
Fugue
45.08
18%
-28
- C4 -
4O7O
1
MAK1_MYCTU
A:
[6-454]
TLATKLP
W
S
D
W
L
S
R
QRWYAGR
N
R
E
L
A
T
-
V
-
K
P
G
V
V
------
V
A
L
R
H
N
L
D
L
V
L
V
D
V
T
Y
T
D
G
A
T
E
R
Y
Q
V
L
V
G
W
D
K
A
A
I
G
--
V
-
A
--
D
D-
R
T
G
F
D
A
L
-
Y
D
V
A
G
P
Q
F
L
L
S
L
I
V
S
SAVC
G
T
S
T
--
G
E
V
T
F
T
R
E
P
D
V
E
L
P
F
A
A
Q
P
R
V
C
D
A
E
Q
S
N
T
S
V
I
F
D
R
R
A
I
L
K
V
F
R
R
V
S
S
G
I
N
P
D
I
E
L
N
R
V
L
T
R
A
G
N
P
H
VARLL
G
A
Y
Q
F
G
D
A
L
A
Y
-
A
L
G
M
V
T
E
Y
E
A
N
A
A
E
G
W
--
A
M
A
T
A
S
V
R
D
-
L
-
F
A
E
G
D
LY
A
H
E
V
G
G
D
F
A
G
E
S
Y
R
L
G
E
A
V
A
S
V
H
A
T
L
A
D
S
L
G
T
-
A
-
Q
A
T
FP
V
D
R
M
L
A
R
L
S
S
T
V
A
V
V
PELREY
A
P
T
I
E
Q
Q
F
Q
K
L
A
A
E
A
I
T
V
Q
-----
R
-
V
H
G
---
D
L
H
L
G
Q
V
L
R
T
P
E
S
W
L
L
I
DFEGEPGQP
L
D
E
R
R
A
P
D
S
P
L
R
D
V
A
G
V
L
R
S
F
E
Y
A
A
Y
G
P
L
VD
Q
A
T
D
K
Q
L
A
A
R
A
R
E
W
V
E
R
N
R
A
A
F
C
D
G
Y
A
V
A
S
G
I
D
P
R
D
S
A
L
L
L
G
A
Y
E
L
D
K
A
V
Y
E
------
T
G
Y
E
T
R
H
R
P
G
W
L
P
I
P
L
R
S
I
A
R
L
T
A
20
PsiBlast_CBE
44.12
31%
-65
- C6 -
4POO
1
?
B:
[6-82]
-------------------------
P
M
-
I
-
L
K
K
I
L
P
Y
S
K
E
L
L
K
M
A
A
G
E
G
D
I
V
I
D
A
T
M
G
N
G
---------
H
D
T
Q
F
L
A
E
L
V
G
-
E
--
N
--
G
H
V
Y
A
F
D
I
Q
E
S
A
V
A
N
T
K
E
R
L
G
E
A
------
Y
Q
--
A
R
T
T
L
F
H
K
S
-----
H
D
K
I
A
K
S
L
P
P
E
--
T
H
G
K
V
A
A
A
V
F
N
L
G
S
S
T
I
K
A
I
E
Q
L
L
S
I
M
K
D
E
G
L
I
V
L
V
V
Y
N
--------
D
V
L
D
F
C
R
N
-
L
D
Q
Q
A
A
R
V
L
T
Y
G
F
I
N
Q
--
Q
N
D
P
P
F
I
V
A
-
I
-
E
K
K
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
37
HHSearch
43.60
9%
-77
- C6 -
1DL5
1
PIMT_THEMA
A:
[59-138]
-----------------------
S
Q
P
S
-
L
-
M
A
L
F
M
------
E
W
V
G
L
D
K
G
M
R
V
L
E
I
G
G
G
T
G
---------
Y
N
A
A
V
M
S
R
--
V
-
V
--
G
EK
G
L
V
V
S
V
E
-
Y
S
R
K
I
C
E
I
A
K
R
N
V
E
R
------
L
G
I-
E
N
V
I
F
V
C
G
D
-----
G
Y
Y
G
V
P
E
F
S
P
Y
--
D
V
I
F
V
T
V
G
V
D
E
V
P
E
T
W
F
T
Q
L
K
E
G
G
R
V
I
V
P
I
N
L
K
L
S
R
R
Q
P
--------
A
F
L
F
K
K
K
D
-
P
Y
L
V
G
N
Y
K
L
E
T
R
F
I
T
A
--
G
G
N
L
G
N
L
L
E
-
R
-
N
R
K
L
L
--
R
E
F
P
F
N
R
E
I
L
L
V
R
S
-----
H
I
F
V
E
L
V
D
L
L
T
R
R
-
L
-
T
E
----
I
D
G
T
F
Y
Y
A
G
P
N
G
--------
V
V
E
F
L
D
D
R
M
R
--
I
Y
G
D
A
P
E
-----
I
-
E
N
L
---
L
T
Q
W
E
S
C
G
Y
R
S
F
E
Y
L
M
L
-------------------
H
V
G
Y
N
A
F
S
H
I
S
C
S
I
-----------------------------------------------------------------------------------------
7
PsiBlast_PDB
43.54
31%
-69
- C6 -
4POO
1
?
A:
[12-82]
---------------------------------
I
L
P
Y
S
K
E
L
L
K
M
A
A
G
E
G
D
I
V
I
D
A
T
M
G
N
G
---------
H
D
T
Q
F
L
A
E
L
V
G
-
E
--
N
--
G
H
V
Y
A
F
D
I
Q
E
S
A
V
A
N
T
K
E
R
L
G
E
A
------
Y
Q
--
A
R
T
T
L
F
H
K
S
-----
H
D
K
I
A
K
S
L
P
P
E
--
T
H
G
K
V
A
A
A
V
F
N
L
G
Y
L
P
G
G
D
I
T
T
N
G
S
S
T
I
K
A
I
E
Q
L
L
S
I
M
K
--------
D
E
G
L
I
V
L
V
-
V
Y
H
E
G
K
A
E
K
N
D
V
L
D
F
C
--
R
N
L
D
Q
Q
A
A
R
-
V
-
L
T
Y
G
F
--
I
N
Q
Q
N
D
P
P
F
I
V
A
I
E
-----
K
K
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
HHSearch
43.27
27%
-55
- C6 -
2YXL
1
?
A:
[254-322]
------------------------------------------
V
L
D
P
K
P
G
E
T
V
V
D
L
A
A
A
P
G
---------
G
K
T
T
H
L
A
E
--
L
-
M
--
K
N
K
G
K
I
Y
A
F
D
-
V
D
K
M
R
M
K
R
L
K
D
F
V
K
R
------
M
G
I-
K
I
V
K
P
L
V
K
D
-----
A
R
K
A
P
E
I
I
G
E
E
--
V
A
D
K
V
L
L
D
A
P
C
T
S
S
G
T
I
G
K
N
P
E
L
R
W
R
L
R
E
D
K
I
N
E
M
S
Q
L
Q
--------
R
E
L
L
E
S
A
A
-
R
L
V
K
P
G
G
R
L
L
Y
T
T
C
S
I
--
F
K
E
E
N
E
K
N
I
-
R
-
W
F
L
N
V
--
H
P
E
F
K
L
V
P
L
K
S
P
Y
D
-----
P
G
F
L
E
G
T
M
R
A
W
P
H
-
R
-
H
S
----
T
I
G
F
F
Y
A
L
L
E
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
44
Fugue
42.67
13%
-28
- C6 -
3EEY
6
?
A:
[3-197]
---------------------
L
T
I
K
N
S
-
L
G
Q
S
H
D
Y
------
I
K
M
F
V
K
E
G
D
T
V
V
D
A
T
C
G
N
G
---------
N
D
T
A
F
L
A
S
--
L
-
V
GE
N
--
G
R
V
F
G
F
D
-
I
Q
D
K
A
I
A
N
T
T
K
K
L
T
D
L
N----
L
I
--
D
R
V
T
L
I
K
D
G
-----
H
Q
N
M
D
K
Y
I
D
C
P
--
V
K
A
V
M
F
N
L
G
Y
L
P
S
G
D
H
S
I
S
T
R
P
E
T
T
I
Q
A
L
S
K
A
M
E
L
L
V
T
G
--------
G
I
I
T
V
V
I
Y
-
Y
G
G
D
T
G
F
E
E
K
E
K
V
L
E
F
L
K
G
V
D
Q
K
K
F
I
V
-
Q
-
R
T
D
F
I
--
N
Q
A
N
C
P
P
I
L
V
C
I
E
K
-----
I
S
E
G
H
H
H
H
H
H
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
38
HHSearch
42.15
16%
-45
- C6 -
2PWY
1
TRMI_THET2
A:
[81-160]
------------------------
Y
P
K
-
D
-
A
S
A
M
V
------
T
L
L
D
L
A
P
G
M
R
V
L
E
A
G
T
G
S
G
---------
G
L
T
L
F
L
A
R
--
A
-
V
--
G
EK
G
L
V
E
S
Y
E
-
A
R
P
H
H
L
A
Q
A
E
R
N
V
R
A
------
F
W
QV
E
N
V
R
F
H
L
G
K
-----
L
E
E
A
E
L
E
E
A
A
Y
--
D
G
V
A
L
D
L
M
E
P
W
K
V
L
E
K
A
A
L
A
L
K
P
D
R
F
L
V
A
Y
L
P
N
I
T
Q
V
L
E
--------
L
V
R
A
A
E
A
H
-
P
F
R
L
E
R
V
L
E
V
G
W
R
E
W
E
--
V
R
L
P
V
A
H
P
R
-
F
-
Q
Q
V
G
H
--
T
A
F
L
V
A
L
R
R
W
K
G
S
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
HHSearch
41.36
13%
-47
- C6 -
3AJD
1
TRM4_METJA
A:
[78-147]
------------------------------------------
V
L
N
P
R
E
D
D
F
I
L
D
M
C
A
A
P
G
---------
G
K
T
T
H
L
A
Q
--
L
-
M
K-
N
K
-
G
T
I
V
A
V
E
-
I
S
K
T
R
T
K
A
L
K
S
N
I
N
R
------
M
G
V-
L
N
T
I
I
I
N
A
D
-----
M
R
K
Y
K
D
Y
L
L
K
N
--
E
I
F
F
D
K
I
L
L
D
A
P
C
S
E
E
D
I
K
Y
C
S
L
R
Q
K
E
L
I
D
I
G
I
D
L
L
K
K
D
--------
G
E
L
V
Y
S
T
C
-
S
M
E
V
E
E
N
E
E
V
I
K
Y
I
L
Q
--
K
R
N
D
V
E
L
I
I
-
I
-
K
A
N
E
F
--
K
G
I
N
I
K
E
G
Y
I
K
G
T
L
-----
R
V
F
P
P
N
E
P
F
F
I
A
K
-
L
-
R
K
----
I
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------