@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Wbm0159: (2015-11-28 )
MVNMSFNCGIVGLPNIGKSTLFNALTQSSAAEAANYPFCTIEPNIGKVPIRDQRLRQIAAIAGSEKVIYNQLEVVDIAGLVKGASKGEGLGNKFLSHIREVDAIVHLLRCFMDDGVNHVHNEIDPISDAEVVEMELILADIDSIEKRLPQLEKKAKQGNKELKRQLDLMHEVLATLKLGKPARSLECSDRNEMKSLQLLTAKPVMYVCNVEDINIITGNKLSQKVKKIAEENKNKFYCISAKLESDIANLESEEEKQSFLSEFGLQESGLDGVARIMYEVLSMITFFTVGLKEARAWPIKIGSTADKAAGVIHNDFEKGFIKAETISFADYVKYRSESACKDAGKIRFEGKDYIVQDGDIMHFRFNV
Atome Classification :
(20 SA)
-----------------------------------------------------------.........10........20.......------.30........40..--......-50....----....60----........70........80-......--.--..90........-100.......110.......120.......130...--....140.......150.......-----160-----......--------.170...-..-..180...--..--...--190..--.......200.-......210......-..--.220.......230...--......240.......250.......260.-..-----....270---------.......280.......290.----....--..-300--........310.......320.......330.......340.......350.......360.....
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-----------------------------------------------------------
M
V
N
M
S
FNCGIVGLPNI
G
K
S
T
L
F
N
A
L
T
Q
S------SAAEAANY
P
F
C
T
IEP--NIGKVP-
I
R
D
Q
R
L
----
R
Q
I
A
A
I----AGSE
K
V
I
Y
NQ
L
E
V
V
D
I
A
G
L
--VKGASK--G--E
G
L
G
N
K
F
L
S
H
I
R
-
E
V
D
A
I
V
H
L
L
R
C
F
M
DD
G
V
N
H
V
HNEIDPISDA
E
V
V
E
M
E
--
L
I
L
A
D
I
D
S
I
E
K
R
L
P
Q
L
E
K
K
A
KQG
N
-----
K
E
L
-----
K
R
Q
L
D
L
--------
M
H
E
V
L
A
T
-
L
K-LGK-PARS--LE--CS
D
--
R
--
N
E
--
M
K
S
L
Q
L
L
TAK
P
-
V
M
Y
V
C
NV--
E
D
I
N
I
I-TG--
N
K
L
S
Q
K
V
K
K
I
A
E
--ENK--N
K
F
Y
C
I
S
A
K
L
E
S
D
I
A
NLE
S
E
E
E
K
Q
S
F
L
S
EF-GL-----QES
G
L
D
G
---------
V
A
R
I
M
Y
E
V
L
S
M
I
T
F
F
T
VGLKE----A
R
A
W
--
P
I
-KI---GST
A
D
K
A
A
G
V
I
H
N
D
F
EKGFIKAETI
S
F
A
D
Y
V
K
YRSESACKDA
G
K
I
R
FEGK
D
Y
I
VQDG
D
I
M
H
F
R
FNV
1
PsiBlast_PDB
95.89
51%
-97
- C5 -
1JAL
-
YCHF_HAEIN
A:
[1-363]
--------------------------------------------------------------
M
G
F
K
C
G
I
V
G
L
P
N
V
G
K
S
T
L
F
N
A
L
T
K
A
-------
G
------
P
F
C
T
I
E
P
--
N
T
G
V
V
P
-
M
P
D
P
R
L
----
D
A
L
A
E
I
----
V
K
P
E
R
I
L
P
T
T
M
E
F
V
D
I
A
G
L
--
V
A
G
A
S
K
--
G
--
E
G
L
G
N
K
F
L
A
N
I
R
-
E
T
D
A
I
G
H
V
V
R
C
F
E
N
---------
I
D
P
L
D
D
I
D
T
I
N
T
E
--
L
A
L
A
D
L
D
S
C
E
R
A
I
Q
R
L
Q
K
R
A
K
G
G
D
-----
K
E
A
-----
K
F
E
L
S
V
--------
M
E
K
I
L
P
V
-
L
E
-
N
A
G
-
M
I
R
S
VG
L
D
--
K
E
E
--
L
--
Q
A
--
I
K
S
Y
N
F
L
T
L
K
P
-
T
M
Y
I
A
N
V
--
N
E
-
D
G
F
-
E
N
--
N
P
Y
L
D
R
V
R
E
I
A
A
--
K
E
G
--
A
V
V
V
P
V
C
A
A
I
E
S
E
I
A
E
L
D
-
D
E
E
K
V
E
F
L
Q
D
L
-
G
I
-----
E
E
P
G
L
N
R
---------
V
I
R
A
G
Y
A
L
L
N
L
Q
T
Y
F
T
A
G
V
K
E
----
V
R
A
W
--
T
V
-
S
V
---
G
A
T
A
P
K
A
A
A
V
I
H
T
D
F
E
K
G
F
I
R
A
E
V
I
A
Y
E
D
F
I
Q
F
N
G
E
N
G
A
K
E
A
G
K
W
R
L
E
G
K
D
Y
I
V
Q
D
G
D
V
M
H
F
R
F
N
V
68
HHSearch
95.49
52%
-99
- C5 -
1JAL
-
YCHF_HAEIN
A:
[3-363]
----------------------------------------------------------------
F
K
C
G
I
V
G
L
P
N
V
G
K
S
T
L
F
N
A
L
T
K
-------
A
G
------
P
F
C
T
I
E
P
--
N
T
G
V
V
P
-
M
P
D
P
R
L
----
D
A
L
A
E
I
----
V
K
P
E
R
I
L
P
T
T
M
E
F
V
D
I
A
G
L
--
V
A
G
A
S
K
--
G
--
E
G
L
G
N
K
F
L
A
N
I
R
-
E
T
D
A
I
G
H
V
V
R
C
F
E
N
---------
I
D
P
L
D
D
I
D
T
I
N
T
E
--
L
A
L
A
D
L
D
S
C
E
R
A
I
Q
R
L
Q
K
R
A
K
G
G
D
-----
K
E
A
-----
K
F
E
L
S
V
--------
M
E
K
I
L
P
V
-
L
E
-
N
A
G
-
M
I
R
S
--
V
G
--
L
D
K
--
E
E
L
Q
A
--
I
K
S
Y
N
F
L
T
L
K
P
-
T
M
Y
I
A
N
V
--
N
E
D
G
F
E
-
N
N
---
P
Y
L
D
R
V
R
E
I
A
A
--
K
E
G
--
A
V
V
V
P
V
C
A
A
I
E
S
E
I
A
E
L
D
-
D
E
E
K
V
E
F
L
Q
D
L
-
G
I
-----
E
E
P
G
L
N
R
---------
V
I
R
A
G
Y
A
L
L
N
L
Q
T
Y
F
T
A
G
V
K
E
----
V
R
A
W
--
T
V
-
S
V
---
G
A
T
A
P
K
A
A
A
V
I
H
T
D
F
E
K
G
F
I
R
A
E
V
I
A
Y
E
D
F
I
Q
F
N
G
E
N
G
A
K
E
A
G
K
W
R
L
E
G
K
D
Y
I
V
Q
D
G
D
V
M
H
F
R
F
N
V
66
HHSearch
93.02
49%
-82
- C5 -
2DBY
4
?
A:
[1-366]
---------------------------------------------------------------
M
L
A
V
G
I
V
G
L
P
N
V
G
K
S
T
L
F
N
A
L
T
R
-------
A
N
A
L
A
A
N
Y
P
F
A
T
I
D
K
--
N
V
G
V
V
P
-
L
E
D
E
R
L
----
Y
A
L
Q
R
T
F
AKG
E
R
V
P
P
V
V
P
T
H
V
E
F
V
D
I
A
G
L
--
V
K
G
A
H
K
--
G
--
E
G
L
G
N
Q
F
L
A
H
I
R
-
E
V
A
A
I
A
H
V
L
R
C
F
P
D
P
-----------
L
E
D
A
E
V
V
E
T
E
--
L
L
L
A
D
L
A
T
L
E
R
R
L
E
R
L
R
K
E
A
R
A
D
R
------
E
R
-----
L
P
L
L
E
A
--------
A
E
G
L
Y
V
H
-
L
Q
-
E
G
K
-
P
A
R
T
--
F
P
--
P
S
E
--
A
V
A
R
F
--
L
K
E
T
P
L
L
T
A
K
P
-
V
I
Y
V
A
N
V
--
A
E
E
D
L
P
-
D
G
RG
N
P
Q
V
E
A
V
R
R
K
A
L
--
E
E
G
--
A
E
V
V
V
V
S
A
R
L
E
A
E
L
A
E
L
S
-
G
E
E
A
R
E
L
L
A
A
Y
-
G
L
-----
Q
E
S
G
L
Q
R
---------
L
A
R
A
G
Y
R
A
L
D
L
L
T
F
F
T
A
G
E
K
E
----
V
R
A
W
--
T
V
-
R
R
---
G
T
K
A
P
R
A
A
G
E
I
H
S
D
M
E
R
G
F
I
R
A
E
V
I
P
W
D
K
L
V
E
A
G
G
W
A
R
A
K
E
R
G
W
V
R
L
E
G
K
D
Y
E
V
Q
D
G
D
V
I
Y
V
L
F
--
3
PsiBlast_PDB
92.04
49%
-83
- C5 -
2DBY
4
?
A:
[4-366]
------------------------------------------------------------------
V
G
I
V
G
L
P
N
V
G
K
S
T
L
F
N
A
L
T
R
A
------
N
A
L
-
A
A
N
Y
P
F
A
T
I
D
K
--
N
V
G
V
V
P
-
L
E
D
E
R
L
Y
A
L
Q
R
T
F
A
K
G
----
E
R
V
P
P
V
V
P
T
H
V
E
F
V
D
I
A
G
L
--
V
K
G
A
H
K
--
G
--
E
G
L
G
N
Q
F
L
A
H
I
R
-
E
V
A
A
I
A
H
V
L
R
C
F
P
D
P
-----------
L
E
D
A
E
V
V
E
T
E
--
L
L
L
A
D
L
A
T
L
E
R
R
L
E
R
L
R
K
E
A
R
-
A
D
-----
R
E
R
-----
L
P
L
L
E
A
--------
A
E
G
L
Y
V
H
-
L
Q
-
E
G
K
-
P
A
R
T
--
F
P
--
P
S
E
A
V
A
--
R
F
--
L
K
E
T
P
L
L
T
A
K
P
-
V
I
Y
V
A
N
V
A
E
E
D
L
P
D
G
-
R
G
--
N
P
Q
V
E
A
V
R
R
K
A
L
--
E
E
G
--
A
E
V
V
V
V
S
A
R
L
E
A
E
L
A
E
L
S
G
E
E
A
R
E
-
L
L
A
A
Y
-
G
L
-----
Q
E
S
G
L
Q
R
---------
L
A
R
A
G
Y
R
A
L
D
L
L
T
F
F
T
A
G
E
K
E
----
V
R
A
W
--
T
V
-
R
R
---
G
T
K
A
P
R
A
A
G
E
I
H
S
D
M
E
R
G
F
I
R
A
E
V
I
P
W
D
K
L
V
E
A
G
G
W
A
R
A
K
E
R
G
W
V
R
L
E
G
K
D
Y
E
V
Q
D
G
D
V
I
Y
V
L
F
--
2
PsiBlast_PDB
91.80
49%
-87
- C5 -
2DWQ
-
?
A:
[4-367]
------------------------------------------------------------------
V
G
I
V
G
L
P
N
V
G
K
S
T
L
F
N
A
L
T
R
A
------
N
A
L
-
A
A
-----
T
I
D
K
--
N
V
G
V
V
P
-
L
E
D
E
R
L
Y
A
L
Q
R
T
F
A
K
G
----
E
R
V
P
P
V
V
P
T
H
V
E
F
V
D
I
A
G
L
--
V
K
G
A
H
K
--
G
--
E
G
L
G
N
Q
F
L
A
H
I
R
-
E
V
A
A
I
A
H
V
L
R
C
F
P
D
P
---------
D
P
L
E
D
A
E
V
V
E
T
E
--
L
L
L
A
D
L
A
T
L
E
R
R
L
E
R
L
R
K
E
A
R
-
A
D
-----
R
E
R
-----
L
P
L
L
E
A
--------
A
E
G
L
Y
V
H
-
L
Q
-
E
G
K
-
P
A
R
T
--
F
P
--
P
S
E
A
V
A
--
R
F
--
L
K
E
T
P
L
L
T
A
K
P
-
V
I
Y
V
A
N
V
AE
E
D
L
P
D
G
-
R
G
--
N
P
Q
V
E
A
V
R
R
K
A
L
--
E
E
G
--
A
E
V
V
V
V
S
A
R
L
E
A
E
L
A
E
L
S
G
E
E
A
R
E
-
L
L
A
A
Y
-
G
L
-----
Q
E
S
G
L
Q
R
---------
L
A
R
A
G
Y
R
A
L
D
L
L
T
F
F
T
A
G
E
K
E
----
V
R
A
W
--
T
V
-
R
R
---
G
T
K
A
P
R
A
A
G
E
I
H
S
D
M
E
R
G
F
I
R
A
E
V
I
P
W
D
K
L
V
E
A
G
G
W
A
R
A
K
E
R
G
W
V
R
L
E
G
K
D
Y
E
V
Q
D
G
D
V
I
Y
V
L
F
N
A
69
HHSearch
87.49
39%
-96
- C5 -
1NI3
1
OLA1_SCHPO
A:
[19-388]
--------------------------------------------------------------
N
N
L
K
T
G
I
V
G
M
P
N
V
G
K
S
T
F
F
R
A
I
T
K
S
------
V
L
G
N
P
A
N
Y
P
Y
A
T
I
D
P
--
E
E
A
K
V
A
-
V
P
D
E
R
F
----
D
W
L
C
E
A
----
Y
K
P
K
S
R
V
P
A
F
L
T
V
F
D
I
A
G
L
--
T
K
G
A
S
T
--
G
--
V
G
L
G
N
A
F
L
S
H
V
R
-
A
V
D
A
I
Y
Q
V
V
R
A
F
D
D
A
E
I
I
H
V
E
G
D
V
D
P
I
R
D
L
S
I
I
V
D
E
--
L
L
I
K
D
A
E
F
V
E
K
H
L
E
G
L
R
K
I
T
S
R
G
A
NTLE
M
K
A
K
-----
K
E
E
Q
A
I
--------
I
E
K
V
Y
Q
Y
-
L
T
E
T
K
Q
-
P
I
R
K
--
G
D
--
W
S
N
--
R
E
V
E
I
--
I
N
S
L
Y
L
L
T
A
K
P
-
V
I
Y
L
V
N
M
--
S
E
R
D
F
L
-
R
Q
K-
N
K
Y
L
P
K
I
K
K
W
I
D
E
N
S
P
G
--
D
T
L
I
P
M
S
V
A
F
E
E
R
L
T
N
F
T
-
E
E
E
A
I
E
E
C
K
K
L
-
N
T
-----
K
-
S
M
L
P
K
---------
I
I
V
T
G
Y
N
A
L
N
L
I
N
Y
F
T
C
G
E
D
E
----
V
R
S
W
--
T
I
-
R
K
---
G
T
K
A
P
Q
A
A
G
V
I
H
T
D
F
E
K
A
F
V
V
G
E
I
M
H
Y
Q
D
L
F
D
Y
K
T
E
N
A
C
R
A
A
G
K
Y
L
T
K
G
K
E
Y
V
M
E
S
G
D
I
A
H
W
K
---
4
PsiBlast_PDB
86.74
38%
-95
- C5 -
1NI3
1
OLA1_SCHPO
A:
[20-388]
---------------------------------------------------------------
N
L
K
T
G
I
V
G
M
P
N
V
G
K
S
T
F
F
R
A
I
T
K
S
------
V
L
G
N
P
A
N
Y
P
Y
A
T
I
D
P
--
E
E
A
K
V
A
-
V
P
D
E
R
F
----
D
W
L
C
E
A
----
Y
K
P
K
S
R
V
P
A
F
L
T
V
F
D
I
A
G
L
--
T
K
G
A
S
T
--
G
--
V
G
L
G
N
A
F
L
S
H
V
R
-
A
V
D
A
I
Y
Q
V
V
R
A
F
D
D
A
E
I
I
H
V
E
G
D
V
D
P
I
R
D
L
S
I
I
V
D
E
--
L
L
I
K
D
A
E
F
V
E
K
H
L
E
G
L
R
K
I
T
S
R
G
A
-----
N
T
L
E
M
K
A
K
K
E
E
Q
A
I
--------
I
E
K
V
Y
Q
Y
-
L
T
-
E
T
K
Q
P
I
R
K
--
G
D
--
W
S
N
--
R
--
E
V
E
I
I
N
S
L
Y
L
L
T
A
K
P
-
V
I
Y
L
V
N
M
--
S
E
R
D
F
L
R
Q
K
--
N
K
Y
L
P
K
I
K
K
W
I
D
--
E
N
S
PG
D
T
L
I
P
M
S
V
A
F
E
E
R
L
T
N
F
-
T
E
E
E
A
I
E
E
C
K
K
L
-
N
T
-----
K
-
S
M
L
P
K
---------
I
I
V
T
G
Y
N
A
L
N
L
I
N
Y
F
T
C
G
E
D
E
----
V
R
S
W
--
T
I
-
R
K
---
G
T
K
A
P
Q
A
A
G
V
I
H
T
D
F
E
K
A
F
V
V
G
E
I
M
H
Y
Q
D
L
F
D
Y
K
T
E
N
A
C
R
A
A
G
K
Y
L
T
K
G
K
E
Y
V
M
E
S
G
D
I
A
H
W
K
---
95
Fugue
58.95
19%
-64
- C5 -
4A9A
-
RBG1_YEAST
B:
[2-369]
S
T
T
V
E
K
I
K
A
I
E
D
E
M
A
R
T
Q
K
N
KAT
S
F
H
L
G
Q
L
K
A
K
L
A
K
L
R
R
E
L
L
T
S
ASSGSGGGAGIGFDV
A
R
T
G
V
A
S
V
G
F
V
G
F
P
S
V
G
K
S
T
L
L
S
K
L
T
G
T
------
E
S
-----------
E
T
--
T
L
V
T
V
P
----------------------
G
V
I
R
Y
K
G
A
K
I
Q
M
L
D
L
P
G
I
--
I
D
G
-----------
G
K
Q
V
I
A
V
A
R
-
T
C
N
L
L
F
I
I
L
D
------------
V
N
K
P
L
H
H
K
Q
I
I
E
K
E
--
L
E
G
V
G
I
-
R
L
N
K
T
P
P
D
I
L
I
K
K
K
E
K
G
---------------------------------------------
G
--
I
S
--
I
T
N
--
T
--
V
P
--
L
T
H
L
G
N
D
E
I
R
A
-
V
M
S
E
Y
R
I
--
N
S
A
E
I
A
-
F
R
--
C
D
A
T
V
D
D
L
I
D
V
L
--
E
A
S
--
S
R
R
Y
M
P
A
I
Y
V
L
N
K
I
D
S
L
S
I
E
E
L
E
L
L
Y
R
I
P
N
-
A
V
P
I
S
SG
Q
D
W
N
L
D
E
---------
L
L
Q
V
M
W
D
R
L
N
L
V
R
I
Y
T
K
P
K
G
Q
----
I
P
D
F
TD
P
V
-
V
L
R
SD
R
C
S
V
K
D
F
C
N
Q
I
H
K
S
L
V
D
D
F
---------
R
N
A
L
V
Y
G
S
S
V
K
H
Q
P
Q
Y
V
---
G
L
S
H
I
L
E
D
E
D
V
V
T
I
L
K
K
-
72
HHSearch
55.09
27%
-79
- C5 -
1UDX
3
OBG_THET8
A:
[156-316]
--------------------------------------------------------------
L
I
A
D
V
G
L
V
G
Y
P
N
A
G
K
S
S
L
L
A
A
M
T
R
-------
A
H
P
K
I
A
P
Y
P
F
T
T
L
S
P
--
N
L
G
V
V
E
-
V
S
E
E
------------------------
E
R
F
T
L
A
D
I
P
G
I
--
I
E
G
A
S
E
--
G
--
K
G
L
G
L
E
F
L
R
H
I
A
-
R
T
R
V
L
L
Y
V
L
D
A
A
D
E
P
-----------
L
K
T
L
E
T
L
R
K
E
--
V
G
A
Y
------------------------------------------------------------
D
---------------------------
P
A
L
L
R
R
P
-
S
L
V
A
L
N
K
--
V
D
L
L
E
E
-
E
A
-----
V
K
A
L
A
D
A
L
A
--
R
E
G
--
L
A
V
L
P
V
S
A
L
T
G
A
G
L
P
A
L
K
E
A
L
H
A
L
V
R
S
T
P
P
-
P
E
-----
M
P
K
P
V
P
Q
---------
A
G
V
E
V
V
P
V
A
E
G
V
Y
E
V
R
A
P
E
V
E
----
R
Y
L
A
--
R
I
-
K
G
---
D
L
M
E
A
A
G
Y
L
Q
E
V
F
R
R
Q
G
V
E
A
A
L
R
A
K
G
V
R
A
G
D
L
V
R
I
G
G
L
E
F
E
Y
I
P
E
V
--------------------
93
Fugue
50.65
23%
11
- C5 -
1WXQ
-
?
A:
[2-395]
-----------------------------------------------------------------
E
I
G
V
V
G
K
P
N
V
G
K
S
T
F
F
S
A
A
T
---------------------
L
A
--
N
V
G
V
T
Y
A
I
T
D
H
P
C
----
K
E
L
G
C
S
----
P
N
P
Q
N
Y
-----
E
Y
R
N
G
L
A
L
--
I
P
V
K
M
--------
V
D
V
A
F
L
D
D
L
R
M
A
S
A
L
I
H
V
V
D
A
T
G
K
T
D
P
E
G
Q
P
T
D
Y
H
D
P
V
E
D
I
E
F
L
E
R
E
--
I
D
Y
W
I
Y
G
I
L
S
K
G
W
D
K
F
A
K
R
I
K
L
Q
K
-----
I
K
L
-----
E
S
A
I
A
E
H
L
SGIGVN
E
N
D
V
W
E
A
M
H
K
-
L
N
L
-
P
E
D
P
--
T
K
WS
Q
D
D
--
L
--
L
A
--
F
A
S
E
I
R
R
V
N
K
P
M
V
I
A
A
N
K
A
--
D
A
A
S
-------
D
E
Q
I
K
R
L
V
R
E
E
E
--
K
R
G
--
Y
I
V
I
P
T
S
A
A
A
E
L
T
L
R
K
A
A
-
K
A
G
F
I
E
Y
I
P
A
L
M
V
I
-----
K
E
K
V
L
D
R
FGSTG
V
Q
E
V
I
N
R
V
V
F
D
L
L
K
L
I
P
V
Y
P
V
H
D
E
Q
FGNV
L
P
H
V
--
F
L
M
K
K
---
G
S
T
P
R
D
L
A
F
K
V
H
T
D
L
G
K
G
F
L
Y
A
I
N
-----------------
A
R
T
K
R
R
V
G
E
D
Y
E
L
Q
F
N
D
I
V
K
I
V
S
V
-
7
PsiBlast_PDB
50.34
29%
-56
- C6 -
1LNZ
2
OBG_BACSU
A:
[160-301]
-----------------------------------------------------------------
D
V
G
L
V
G
F
P
S
V
G
K
S
T
L
L
S
V
V
S
-
S
------
A
K
P
K
I
A
D
Y
H
F
T
T
L
V
P
--
N
L
G
M
V
E
-
T
D
D
G
R
------------------------
S
F
V
M
A
D
L
P
G
L
--
I
E
G
A
H
Q
--
G
--
V
G
L
G
H
Q
F
L
R
H
I
E
-
R
T
R
V
I
V
H
V
I
D
M
S
G
L
E
G
R
-------
D
P
Y
D
D
Y
L
T
I
N
Q
E
--
L
S
E
Y
N
L
R
L
T
E
R
--
P
Q
I
I
V
A
N
K
M
D
M
-----
P
E
A
-----
A
E
N
L
E
A
--------
F
K
E
K
L
T
D
-
D
Y
-
P
V
F
-
P
I
S
A
--
V
T
--
R
E
G
--
L
--
R
E
--
L
L
F
E
V
A
N
Q
L
E
N
-
T
P
E
F
P
L
Y
--
D
E
E
E
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
96
Fugue
48.61
16%
-41
* C5 *
1M2O
2
SAR1_YEAST
B:
[24-190]
----------------------------------------------------------------
G
K
L
L
F
L
G
L
D
N
A
G
K
T
T
L
L
H
M
L
K
N
D
------
R
L
A
T
L
Q
P
----
T
W
H
P
--
T
S
E
E
L
A
-
I
G
N
-------------------------
I
K
F
T
T
F
D
L
G
G
-----------
H
--
I
Q
A
R
R
L
W
K
D
Y
F
P
-
E
V
N
G
I
V
F
L
V
D
A
A
D
P
E
R
F
D
E
A
R
V
E
L
D
A
L
F
N
I
A
E
L
K
D
V
P
F
V
I
L
G
N
K
I
D
A
P
N
A
V
S
E
A
E
L
R
S
A
L
G
L
-----
L
N
T
-----
T
G
I
E
G
Q
--------
R
P
V
E
V
F
M
-
C
S
-
V
V
M
-
R
N
G
Y
--
L
E
--
A
F
Q
--
W
--
L
S
--
Q
Y
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
48.61
34%
-88
- C4 -
1UDX
3
OBG_THET8
A:
[159-243]
-----------------------------------------------------------------
D
V
G
L
V
G
Y
P
N
A
G
K
S
S
L
L
A
A
M
T
R
A
------
H
P
-
K
I
A
P
Y
P
F
T
T
L
S
P
--
N
L
G
V
V
E
-
V
S
E
E
------------------------
E
R
F
T
L
A
D
I
P
G
I
--
I
E
G
A
S
E
--
G
--
K
G
L
G
L
E
F
L
R
H
I
A
-
R
T
R
V
L
L
Y
V
L
D
A
A
D
E
P
L
K
T
L
E
T
L
R
K
E
V
G
A
Y
D
P
A
L
L
R
R
--
P
S
L
V
A
L
N
K
V
D
L
L
E
E
E
A
V
K
A
L
A
D
A
L
-----
A
R
E
-----
G
L
A
V
L
P
--------
V
S
A
L
T
G
A
-
G
L
-
P
A
L
-
K
E
A
L
--
H
A
--
L
V
R
--
S
--
T
P
--
P
P
E
M
P
K
P
V
P
Q
A
-
G
V
E
V
V
P
V
--
A
E
G
V
Y
E
-
V
R
--
A
P
E
V
E
R
Y
L
A
R
I
K
--
G
D
L
--
M
E
A
A
G
Y
L
Q
E
V
F
R
R
Q
G
V
E
A
A
L
R
A
K
G
V
R
A
G
D
L
-
V
R
-----
I
G
G
L
E
F
E
---------
Y
I
P
E
V
----------------------------------------------------------------------------------------------------
99
Fugue
47.90
16%
-43
- C3 -
3I8S
-
FEOB_ECOLI
B:
[1-261]
-------------------------------------------------------------
M
K
K
L
T
I
G
L
I
G
N
P
N
S
G
K
T
T
L
F
N
Q
L
T
-
G
------
S
R
Q
R
V
G
N
W
A
G
V
T
V
E
R
--
K
E
G
Q
F
S
-
T
T
D
H
-------------------------
Q
V
T
L
V
D
L
P
G
T
--
Y
S
L
T
T
I
--
S
--
S
Q
------
T
S
L
D
-
E
Q
I
A
C
H
Y
I
L
S
----
G
D
A
D
L
L
I
N
V
V
D
A
S
N
L
E
R
N
L
Y
L
T
--
L
Q
L
L
E
L
G
I
---------------------------------------------
P
C
I
V
A
-
L
N
-
M
L
D
-
I
A
E
K
-----------
Q
--
N
I
--
R
I
E
I
D
A
L
S
A
R
L
-
G
C
P
V
I
P
L
--
V
S
T
R
G
R
-
G
I
--
E
A
L
K
L
A
I
D
R
Y
K
A
--
N
E
N
--
V
E
L
V
H
Y
A
Q
P
L
L
N
E
A
D
S
L
A
K
V
M
P
S
D
I
-------------------
P
---------
L
K
Q
R
R
W
L
G
L
Q
M
L
E
G
D
I
Y
S
R
A
Y
----
A
G
E
A
--
S
Q
-
H
L
---
D
A
A
L
A
R
L
R
N
E
M
D
D
--
P
A
L
H
I
A
D
A
R
Y
Q
C
I
A
A
I
C
D
V
V
S
N
-----------------------------
73
HHSearch
47.45
37%
-87
- C6 -
1LNZ
2
OBG_BACSU
A:
[157-249]
--------------------------------------------------------------
V
L
A
D
V
G
L
V
G
F
P
S
V
G
K
S
T
L
L
S
V
V
S
S
-------
A
K
P
K
I
A
D
Y
H
F
T
T
L
V
P
--
N
L
G
M
V
E
-
T
D
D
G
------------------------
R
S
F
V
M
A
D
L
P
G
L
--
I
E
G
A
H
Q
--
G
--
V
G
L
G
H
Q
F
L
R
H
I
E
-
R
T
R
V
I
V
H
V
I
D
M
S
G
L
E
G
R
D
P
Y
D
D
Y
L
T
I
N
Q
E
L
S
E
Y
N
L
R
--
L
T
E
R
P
Q
I
I
V
A
N
K
M
D
M
P
E
A
A
E
N
L
E
A
-----
F
K
E
-----
K
L
T
D
D
Y
--------
P
V
F
P
I
S
A
-
V
T
-
R
E
G
-
L
R
E
L
--
L
F
--
E
V
A
--
N
--
Q
L
--
E
N
T
P
E
F
P
L
Y
D
E
-
E
E
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
84
HHSearch
46.48
28%
-114
- C6 -
1MKY
3
DER_THEMA
A:
[2-93]
----------------------------------------------------------------
A
T
V
L
I
V
G
R
P
N
V
G
K
S
T
L
F
N
K
L
V
K
--------------------
D
P
--
V
Q
D
T
V
E
-
W
Y
G
-------------------------
K
T
F
K
L
V
D
T
C
G
V
--
F
D
N
P
Q
D
II
S
--
Q
K
M
K
E
V
T
L
N
M
I
R
-
E
A
D
L
V
L
F
V
V
D
G
K
R
G
I
T
K
E
D
E
S
L
A
D
F
L
R
K
S
T
V
D
T
I
L
V
--
A
N
K
A
E
N
L
R
E
F
E
R
E
V
K
P
E
L
Y
S
L
G
F
G
-----
E
P
I
-----
P
V
S
A
E
H
--------
N
I
N
L
D
T
M
-
L
E
-
T
I
I
-
K
K
L
E
--
E
K
--
G
L
D
--
L
--
E
S
--
K
P
E
I
T
D
A
I
K
V
A
-
I
V
G
R
P
N
V
--
G
K
S
T
L
F
-
N
A
--
I
L
N
K
E
R
A
L
V
S
P
I
--
P
V
D
--
D
E
V
F
I
D
G
R
K
Y
V
F
V
D
T
A
G
L
E
K
Y
S
N
Y
R
V
V
D
S
I
-
E
K
-----
A
D
V
V
V
I
V
---------
L
D
A
T
Q
G
I
T
R
Q
D
Q
R
M
A
G
L
M
E
R
R
----
G
R
A
S
--
V
V
-
V
F
---
N
K
W
D
L
V
V
H
R
E
K
R
Y
D
E
F
T
K
L
F
R
E
K
L
Y
F
I
D
Y
S
P
L
I
F
T
S
A
D
K
G
W
N
I
D
R
M
I
D
A
M
N
L
A
Y
A
S
Y
T
T
K
V
P
S
S
A
I
35
PsiBlast_CBE
46.23
35%
-92
- C4 -
4DCS
1
DER_BACSU
A:
[26-102]
------------------------------------------------------------------
V
A
I
V
G
R
P
N
V
G
K
S
T
I
F
N
R
I
A
G
E
RISRIY
S
S
A
E
W
L
N
Y
D
F
N
L
I
D
T
GG-----
P
-
F
L
A
Q
-
I
----
R
Q
Q
A
E
I
----
A
M
D
E
A
D
V
I
I
F
M
V
N
G
R
E
G
V
T
--
A
A
D
E
E
V
--
A
--
K
I
L
Y
R
T
K
K
P
V
V
L
-
A
V
N
K
L
M
R
A
N
I
Y
D
F
Y
S
L
G
F
G
E
P
Y
P
I
S
G
T
H
G
L
G
L
G
D
L
L
--
D
A
V
A
E
H
F
K
N
I
P
E
T
K
Y
N
E
E
V
I
Q
F
C
L
-----
I
G
R
-----
P
N
V
G
K
S
--------
S
L
V
N
A
M
L
-
G
E
-
E
R
V
-
I
V
S
N
--
D
A
--
V
D
T
--
S
--
F
T
--
Y
N
Q
Q
E
F
V
I
V
D
T
-
A
G
M
R
K
K
G
--
K
V
Y
E
T
T
-
E
K
--
Y
S
V
L
R
A
L
K
A
I
D
R
--
S
E
V
--
V
A
V
V
L
D
G
E
E
G
I
I
E
Q
D
K
R
I
A
G
Y
A
H
E
A
G
K
A
V
V
-
I
V
-----
V
N
K
W
D
A
V
---------
D
K
D
E
S
T
M
K
E
F
E
E
N
I
R
D
H
F
Q
F
L
----
D
Y
A
P
--
I
L
-
F
M
---
S
A
L
T
K
K
R
I
H
T
L
M
P
A
I
I
K
A
S
E
N
H
S
L
R
V
Q
T
N
V
L
N
D
V
I
M
D
A
V
A
M
N
P
T
P
T
H
N
G
S
R
L
K
I
Y
Y
A
T
Q
V
S
V
K
P
P
S
22
PsiBlast_CBE
45.51
32%
-62
- C4 -
3W5I
1
?
B:
[6-77]
------------------------------------------------------------------
I
A
L
L
G
M
P
N
T
G
K
S
T
L
F
N
R
M
T
-
G
------
G
A
A
R
V
G
N
W
P
G
I
T
V
E
L
--
L
S
G
K
I
-----------------
L
----
L
G
A
D
M
V
-----
E
I
I
D
L
P
G
I
YD
L
H
G
F
S
D
--
D
--
E
Q
V
V
R
H
F
L
H
D
N
V
-
P
D
L
A
L
V
I
L
N
A
T
Q
I
E
R
Q
M
S
L
L
L
Q
L
K
Q
L
N
M
N
I
V
V
L
L
N
M
--
S
D
E
A
K
Q
Y
G
I
T
I
D
S
R
K
M
S
E
L
L
Q
I
P
V
-----
F
Q
L
-----
S
G
T
G
Y
Q
--------
E
A
L
Q
A
V
T
-
R
A
-
L
R
Y
-
P
T
P
G
--
M
A
--
E
N
V
--
R
--
T
Q
--
L
E
Q
D
E
H
I
E
A
E
M
-
V
R
I
L
K
S
A
--
V
Q
I
P
A
R
-
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34
PsiBlast_CBE
45.26
35%
-97
- C4 -
4DCT
2
DER_BACSU
A:
[26-102]
------------------------------------------------------------------
V
A
I
V
G
R
P
N
V
G
K
S
T
I
F
N
-
I
A
G
E
RISRIY
S
S
A
E
W
L
N
Y
D
F
N
L
I
D
T
GG-----
P
-
F
L
A
Q
-
I
----
R
Q
Q
A
E
I
----
A
M
D
E
A
D
V
I
I
F
M
V
N
G
R
E
G
V
T
--
A
A
D
E
E
V
--
A
--
K
I
L
Y
R
T
K
K
P
V
V
L
-
A
V
N
K
L
N
I
Y
D
F
Y
S
L
G
F
G
E
P
Y
P
I
S
G
T
H
G
L
G
L
G
D
L
L
D
A
V
--
A
E
H
F
K
N
I
P
E
T
K
Y
N
E
E
V
I
Q
F
C
L
I
G
R
-----
P
N
V
-----
G
K
S
S
L
V
--------
N
A
M
L
G
E
E
-
R
V
-
I
V
S
-
N
D
A
V
--
D
T
--
S
F
T
--
Y
--
N
Q
--
Q
E
F
V
I
V
D
T
A
G
M
-
R
K
K
G
K
V
Y
--
E
T
T
E
K
Y
-
S
V
--
L
R
A
L
K
A
I
D
R
S
E
V
--
V
A
V
--
V
L
D
G
E
E
G
I
I
E
Q
D
K
R
I
A
G
Y
A
H
E
A
G
K
A
V
V
I
V
V
-
N
K
-----
W
D
A
V
D
K
D
---------
E
S
T
M
K
E
F
E
E
N
I
R
D
H
F
Q
F
L
D
Y
A
----
P
I
L
F
--
M
S
-
A
L
---
T
K
K
R
I
H
T
L
M
P
A
I
I
K
A
S
E
N
H
S
L
R
V
Q
T
N
V
L
N
D
V
I
M
D
A
V
A
M
N
P
T
P
T
H
N
G
S
R
L
K
I
Y
Y
A
T
Q
V
S
V
K
P
P
S
F
V
V
80
HHSearch
44.70
27%
-52
- C6 -
2WJG
1
FEOB_METJA
A:
[4-97]
------------------------------------------------------------
H
M
K
S
Y
E
I
A
L
I
G
N
P
N
V
G
K
S
T
I
F
N
A
L
T
G
-------
E
N
V
Y
I
G
N
W
P
G
V
T
V
E
K
--
K
E
G
E
F
E
-
Y
N
G
-------------------------
E
K
F
K
V
V
D
L
P
G
V
--
Y
S
L
T
A
N
--
S
I
D
E
I
I
A
R
D
-
Y
I
I
N
E
-
K
P
D
L
V
V
N
I
V
D
A
T
A
L
E
R
N
L
Y
L
T
L
Q
L
M
E
M
G
A
N
L
L
L
A
L
N
--
K
M
D
L
A
K
S
L
G
I
E
I
D
V
D
K
L
E
K
I
L
G
V
K
-----
V
V
P
-----
L
S
A
A
K
K
--------
M
G
I
E
E
L
K
-
K
A
-
I
S
I
-
A
V
K
D
--
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------