@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Wbm0186: (2015-11-29 )
MAVRLIPDNLNIKFSKYRKLTALISIILVIFSLFIVVLRGVNLGIDFTGGILMEIKSSSEDHAVLNILKENGFTIQSSKAGNNLVMYFREEGNEGKIKKIKSVLEEKLGSSISYRKIDYIGPRISSTQILEGILSMFIAIVGIFFYVWFRFNWQCGFGGTIALIHDVILTVGFVSLTGIKFNISSVAALLTVIGYSINNSVVIYDRIREYQKSGKNRQMSDIVDASINVTLFRTVLTSGTTLLATIPLTLICTDTVRDFSLIIFFGILIGTCSAIFISAPILTCKVLISRIAV
Atome Classification :
(20 SA)
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.......-..10........20........30........40........50........--60-------..----......70..-----.--------.-----....80........90.-----------------------------.......100.......110.......120----------.........130.......140.......150------------.-.......160.......170..---.....180.......190......-----------------.200.......210...---------....220......--.230..---......240.......250-..---.---......260.......270.......280.......290.--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
A
V
R
LIP-DNL
N
I
K
F
S
K
Y
R
K
L
T
A
L
I
S
I
I
L
V
I
F
S
L
F
I
V
V
L
RGVNL
G
I
D
FTG
G
I
L
M
E
IKSSS--E
D
-------
H
A
----
V
L
N
I
L
K
EN
G
F
-----
T
--------
I
-----QSSKAGN
N
L
V
M
Y
F
REEG-----------------------------NE
G
K
I
K
K
I
K
S
V
L
E
E
KLGSSIS
Y
R
K
I
D
YI------------GPRI
S
S
T
Q
I
L
E
G
I
L
S
M
F
I
A
I
V
G
I
F
F
Y
V
W
F
R
F
-------------
N
-
W
QCGFG
G
T
I
A
L
I
H
D
V
I
L
T
V
G
F
V
---
S
LT
G
I
K
F
N
I
S
S
V
A
A
L
L
T
V
I
GYSIN-----------------
N
S
V
V
I
Y
D
R
I
R
E
Y
Q
K
SGK---------NR
Q
M
S
D
I
VDAS
I
N
--
V
T
-
L
F
R
---
T
V
LTSG
T
T
L
L
A
TI
P
L
T
L
---
I
C
---T---DTVR
D
F
S
L
I
I
F
F
G
I
L
I
GT
C
S
A
I
F
IS
A
P
I
L
T
C
K
V
L
I
S
R
IAV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
HHSearch
89.25
31%
-123
* C2 *
3AQP
-
SECDF_THET8
A:
[440-726]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
R
F
N
F
M
G
P
A
R
Y
V
T
A
A
T
L
L
L
A
A
L
A
A
G
V
V
F
A
K
G
F
N
Y
S
I
D
F
T
G
G
T
A
Y
T
L
R
A
-
E
--
P
N
VE
V
----
E
T
----
L
R
R
F
L
E
E
K
G
F
PGKE
A
V
--------
I
-----
T
Q
V
--
Y
R
E
F
L
V
K
L
P
P
L
------------------------------
S
D
E
R
R
L
E
L
E
R
L
F
A
S
E
L
K
A
--
T
V
L
A
S
E
T
V
------------
G
P
A
I
G
E
E
L
R
R
N
A
V
M
A
V
L
V
G
L
G
L
I
L
L
Y
V
A
F
R
F
-------------
D
-
W
T
F
G
V
A
S
I
L
A
V
A
H
D
V
A
I
V
A
G
M
Y
---
S
L
L
G
L
E
F
S
I
P
T
I
A
A
L
L
T
I
V
G
Y
S
I
N
-----------------
D
S
I
V
V
S
D
R
I
R
E
N
Q
K
L
L
R
---------
H
L
P
Y
A
E
L
V
N
R
S
I
N
--
Q
T
-
L
S
R
---
T
V
M
T
S
L
T
T
L
L
P
I
L
A
L
L
F
---
L
G
---
G
---
S
V
L
R
D
F
A
L
A
I
F
V
G
I
F
V
G
T
Y
S
S
I
Y
V
V
S
A
L
V
V
A
W
K
N
R
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
83.69
33%
-114
- C2 -
3AQP
-
SECDF_THET8
A:
[465-715]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
V
F
A
K
G
F
N
Y
S
I
D
F
T
G
G
T
A
Y
T
L
R
A
E
P
NV
E
V
-------
E
T
----
L
R
R
F
L
E
E
K
G
F
-----
P
GKE
A
V
I
T
Q
V
-----------
Y
R
E
F
L
V
K
L
P
P
L
-----------------------------
S
D
E
R
R
L
E
L
E
R
L
F
A
S
E
L
K
A
T
V
L
A
S
--
E
T
V
------------
G
P
A
I
G
E
E
L
R
R
N
A
V
M
A
V
L
V
G
L
G
L
I
L
L
Y
V
A
F
R
F
-------------
D
-
W
T
F
G
V
A
S
I
L
A
V
A
H
D
V
A
I
V
A
G
M
Y
---
S
L
L
G
L
E
F
S
I
P
T
I
A
A
L
L
T
I
V
G
Y
S
I
N
-----------------
D
S
I
V
V
S
D
R
I
R
E
N
Q
K
L
L
R
---------
H
L
P
Y
A
E
L
V
N
R
S
I
N
--
Q
T
-
L
S
R
---
T
V
M
T
S
L
T
T
L
L
P
I
L
A
L
L
F
---
L
G
---
G
---
S
V
L
R
D
F
A
L
A
I
F
V
G
I
F
V
G
T
Y
S
S
I
Y
V
V
S
A
L
V
V
A
W
K
N
R
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
Fugue
61.88
18%
-97
- C2 -
4MT1
-
?
A:
[2-1040]
A
K
F
F
I
D
R
P
I
F
A
W
V
I
S
I
F
I
I
A
A
G
I
F
G
I
K
S
LPVSQYPSVA
A
P
T
I
T
L
H
A
I
Y
PGAS
A
Q
V
M
E
G
SV
L
S
V
I
E
R
N
MNGVEGLD
Y
M
S
T
S
A
D
SSG
S
G
S
V
S
L
T
F
T
PDTD
E
N
L
A
Q
V
E
V
Q
N
K
L
S
E
V
LSTLP
A
T
V
Q
Q
Y
G
V
T
V
S
KARSNFL
M
I
V
M
L
S
S
DVQS
T
E
E
M
N
D
Y
A
Q
R
N
V
VPELQRIEGVG
Q
V
R
L
FGAQRAM
R
I
W
V
D
P
K
K
L
Q
N
Y
NLS
F
A
D
V
G
S
A
L
S
A
Q
N
I
Q
I
S
A
G
S
I
GSLPAVRGQ
T
V
T
A
T
V
T
A
Q
GQLGT
A
E
E
F
G
N
VILRANTDG
S
N
I
Y
LKDVAK
V
G
L
G
M
EDYS
S
S
T
R
L
NG
V
N
T
T
G
M
A
V
M
L
S
NSGNA
M
A
T
A
K
A
V
K
E
R
L
A
V
L
E
K
Y
FPQG
M
S
W
K
T
PYDT
S
K
F
V
E
I
S
I
E
K
V
I
H
T
L
I
E
A
M
V
L
V
F
V
V
M
Y
L
F
L
QNIRYT
L
I
P
T
I
V
V
P
I
S
L
L
G
G
F
A
F
I
S
Y
M
GMSIN
V
L
T
M
F
A
M
I
L
V
I
GIVV
D
D
A
I
V
V
V
E
N
V
E
R
I
M
A
G
EGLP
P
K
E
A
T
K
K
A
M
G
Q
I
S
G
A
V
I
G
I
T
A
V
L
I
S
V
F
VPLAMFSG
A
A
G
N
I
Y
K
Q
F
A
L
T
M
A
S
S
I
A
F
S
A
F
L
A
L
TLT
P
A
L
C
A
TG
F
F
G
W
F
N
K
K
F
D
S
W
T
H
G
Y
E
G
R
V
A
K
V
L
R
K
T
F
R
M
M
V
V
Y
I
G
L
A
V
V
G
V
F
L
F
M
R
L
P
T
S
F
L
PTEDQG
F
V
M
V
S
V
Q
L
P
A
GAT
K
E
R
T
D
A
T
L
A
Q
V
T
Q
L
A
K
S
IPEIE
N
I
I
T
V
S
GFSFSGSGQN
M
A
M
G
F
AIFKDWNERTASGSD
A
V
A
V
A
G
K
L
T
G
M
M
M
G
TLKD
G
F
G
I
A
V
V
P
P
PILELG
S
G
L
S
I
N
L
Q
D
RNNTG
H
T
A
L
L
A
K
R
N
E
L
I
Q
K
M
R
A
SGLFDPST
V
R
A
G
G
L
E
D
S
P
Q
L
K
I
D
I
N
R
A
A
A
A
A
QGIS
F
A
D
I
R
T
A
L
A
S
A
LS
S
S
Y
V
S
D
F
P
N
QG
R
L
Q
R
V
M
V
Q
A
D
E
D
A
R
M
Q
P
A
D
I
L
N
L
T
V
P
N
K
S
G
V
A
V
P
L
S
T
I
-----
A
T
V
S
W
E
N
G
T
E
Q
S
V
R
F
N
G
Y
P
S
M
K
L
S
A
S
P
--
A
T
-------
G
-----
V
S
T
G
Q
A
M
E
A
V
-----
Q
--------
K
-----
M
V
D
E
L
G
G
G
Y
S
F
E
W
G
G
Q
S
-----------------------------
S
E
E
A
K
G
G
S
Q
T
L
I
L
Y
G
L
A
V
A
A
V
F
L
V
L
A
A
L
------------
Y
E
S
W
S
I
P
L
A
V
--
I
L
V
I
P
L
G
L
I
G
A
A
A
G
V
T
G
R
N
-------------
L
-
F
E
G
L
L
G
S
V
P
S
F
A
N
D
-------------------
I
Y
F
Q
V
G
F
V
T
V
M
G
L
S
A
K
-----------------
N
A
I
L
I
I
E
F
A
K
D
L
Q
A
Q
G
K
---------
S
--
A
V
E
A
A
L
E
A
A
R
--
L
R
-
F
R
P
---
I
I
M
T
S
F
A
F
I
L
G
V
V
P
L
Y
I
AAG
A
S
---
S
---
A
S
Q
R
A
I
G
T
T
V
F
W
G
M
L
V
G
T
L
L
S
V
F
L
-
V
P
L
F
Y
V
V
V
R
K
F
F
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
HHSearch
60.56
22%
-119
- C2 -
3AQP
-
SECDF_THET8
A:
[253-429]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
L
K
V
A
E
I
R
A
I
------------
G
P
T
L
G
Q
D
A
I
Q
A
G
I
R
S
A
L
I
G
T
L
A
I
F
L
L
I
F
A
Y
Y
-------------
G
-
P
H
L
G
L
V
A
S
L
G
L
L
Y
T
S
A
L
I
L
G
L
L
---
S
G
L
G
A
T
L
T
L
P
G
I
A
G
L
V
L
T
L
G
A
A
V
D
-----------------
G
N
V
L
S
F
E
R
I
K
E
E
L
R
A
G
K
-----------
K
L
R
Q
A
I
P
E
G
F
R
--
H
S
-
T
L
T
---
I
M
D
V
N
I
A
H
L
L
A
A
A
A
L
Y
Q
---
Y
A
---
T
---
G
P
V
R
G
F
A
V
I
L
A
I
G
V
V
A
S
V
F
S
N
L
V
F
S
R
H
L
L
E
R
L
A
D
R
G
E
I
R
P
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
38
Fugue
55.60
9%
-91
- C2 -
1IWG
-
ACRB_ECOLI
A:
[7-1036]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DRP
I
F
A
W
V
I
A
I
I
I
M
L
A
G
G
L
A
I
L
K
LPVAQYPTIA
P
P
A
V
T
I
S
A
S
Y
P
GAD
A
K
T
V
Q
D
TVT
Q
V
I
E
Q
N
MNGIDNLM
Y
M
S
S
N
S
D
STG
T
V
Q
I
T
L
T
F
E
SGTD
A
D
I
A
Q
V
Q
V
Q
N
K
L
Q
L
A
MPLLP
Q
E
V
Q
Q
Q
G
V
S
V
E
K
S
SSSFLMVV
G
V
I
N
T
DGTMT
Q
E
D
I
S
D
Y
V
A
A
NMKDAISRTSGVG
D
V
Q
L
FGSQYAM
R
I
W
M
N
P
N
E
L
N
K
F
QLT
P
V
D
V
I
T
A
I
K
A
Q
N
A
Q
V
A
A
G
Q
L
G
-
G
T
P
P
V
K
G
Q
Q
L
N
A
S
I
I
A
Q
T
R
L
T
S
T
E
E
F
G
K
I
L
L
K
V
N
Q
D
G
S
R
V
L
L
R
D
V
A
K
I
E
L
G
G
--
E
N
-------
Y
D
----
I
I
A
E
F
N
G
Q
P
A
-----
S
--------
G
-----
L
G
I
K
L
A
T
G
A
N
A
L
D
T
A
A
A
-----------------------------
I
R
A
E
L
A
K
M
E
P
F
F
P
S
G
L
K
I
V
Y
P
Y
D
T
T
P
F
V
------------
K
I
S
I
H
E
V
V
K
T
L
V
E
A
I
I
L
V
F
L
V
M
Y
L
F
L
Q
-----------------
N
-
F
R
A
T
L
I
P
T
I
A
V
P
V
V
L
L
G
T
F
A
V
L
---
A
A
F
G
F
S
I
N
T
L
T
M
F
G
M
V
L
A
I
G
L
L
V
D
-----------------
D
A
I
V
V
V
E
N
V
E
R
V
M
A
E
E
G
---------
L
P
P
K
E
A
T
R
K
S
M
G
Q
-----
I
Q
G
---
A
L
V
G
I
A
M
V
L
S
A
V
F
V
P
M
A
---
F
F
---
G
---
G
S
T
G
A
I
Y
R
Q
F
S
I
T
I
V
S
A
M
A
L
S
V
L
V
A
L
I
L
T
P
A
L
C
A
T
M
L
K
F
G
W
F
N
R
M
F
E
K
S
TH
H
Y
T
D
S
V
G
G
I
L
R
S
T
G
R
Y
L
V
L
Y
L
I
I
V
V
G
M
A
Y
L
F
V
R
L
P
S
S
F
L
P
D
E
D
QG
V
F
M
T
M
V
Q
L
P
A
GAT
Q
E
R
T
Q
K
V
L
N
E
V
T
H
Y
Y
L
TKEKNNVE
S
V
F
A
V
N
GFGFAGRGQN
T
G
I
A
F
V
S
L
K
DWADRPGEENK
V
E
A
I
T
M
R
A
T
R
A
F
S
Q
IKD
A
M
V
F
A
F
N
LPAIVELGTAT
G
F
D
F
E
L
I
DQAGLG
H
E
K
L
T
Q
A
R
N
Q
L
L
A
E
A
A
K
H
PM
L
T
S
V
R
P
NGLE
D
T
P
Q
F
K
I
D
I
D
Q
E
K
A
Q
A
L
GVS
I
N
D
I
N
T
T
L
G
A
A
WGGSYV
N
D
F
I
D
RG
R
V
K
K
V
Y
V
M
S
E
AKYRMLPDDIGD
W
Y
V
R
A
ADG
Q
M
V
P
FSAF
S
S
S
R
W
E
Y
G
S
P
R
L
E
R
Y
NG
L
P
S
M
E
I
L
G
Q
A
APGKS
T
G
E
A
M
E
L
M
E
Q
L
A
SKLPTG
V
G
Y
D
WSGNQ
A
P
S
L
Y
A
I
S
L
I
V
V
F
L
C
L
A
ALYESWSIPFSV
M
L
V
V
P
L
G
V
I
G
A
L
L
A
A
T
F
R
GLTND
V
Y
F
Q
V
G
L
L
T
T
I
G
L
S
A
K
N
A
I
L
I
V
E
F
A
K
D
L
M
DKEGKGL
I
E
A
T
L
D
A
V
R
M
R
L
R
P
I
L
M
T
S
L
A
F
I
L
G
V
M
P
L
V
ISTGAGSG
A
Q
N
A
V
G
T
G
V
M
G
G
M
V
T
A
TVLAIFFVPV
F
F
V
V
V
RRRFSRK
35
Fugue
52.22
11%
-117
- C2 -
2I57
4
?
A:
[4-422]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FRIA
Q
D
V
V
A
R
E
N
D
R
R
A
S
A
L
K
E
D
Y
E
A
L
G
-
A
N
L
A
R
R
G
V
D
I
E
A
V
T
A
K
V
E
K
F
F
V
A
V
P
S
W
G
V
G
T
G
G
T
R
F
A
R
F
P
G
T
G
E
P
R
G
I
F
D
K
L
--
D
D
-------
C
A
----
V
I
Q
Q
L
T
R
A
T
P
-----
N
--------
V
S
L
H
I
P
W
D
K
A
D
P
K
E
L
K
A
R
G
D
A
L
G
L
G
F
D
A
M
N
S
N
TFSDAPGQAHSYKYGSLSHT
N
A
A
T
R
A
Q
A
V
E
H
N
L
E
C
I
E
I
G
K
A
I
G
S
K
A
L
T
V
W
I
GDGSNFPGQ
S
N
F
T
R
A
F
E
R
Y
L
S
A
M
A
E
I
Y
K
G
L
P
D
D
W
K
L
F
S
E
H
K
MYEPAFYSTVVQ
D
-
W
G
T
N
Y
L
I
A
Q
T
L
G
P
K
A
Q
C
L
V
D
L
G
HHA
P
N
T
N
I
E
M
I
V
A
R
L
I
Q
F
G
K
L
G
G
F
H
F
N
D
S
KYGDDDLDAGAIE
P
Y
R
L
F
L
V
F
N
E
L
V
D
A
E
A
R
G
V
K--------
G
F
H
P
A
H
M
I
D
Q
S
H
N
--
V
T
D
P
I
E
---
S
L
I
N
S
A
N
E
I
R
R
A
Y
A
Q
A
L
---
L
V
---
D
---
R
A
A
L
S
G
Y
Q
E
D
N
D
A
L
M
A
T
E
T
L
K
R
A
Y
R
T
D
V
---
E
P
I
L
A
E
A
R
R
R
T
GGAVD
P
V
A
T
Y
R
A
S
G
Y
R
A
R
V
A
A
E
R
PAS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
50.46
23%
-129
- C2 -
4MT1
-
?
A:
[899-1028]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
L
V
I
P
L
G
L
I
G
A
A
A
G
V
T
G
R
N
-------------
L
-
F
E
G
L
L
G
S
V
P
S
F
A
N
D
I
Y
F
Q
V
G
F
V
-------------------
T
V
M
G
L
S
A
K
-----------------
N
A
I
L
I
I
E
F
A
K
D
L
Q
A
Q
G
K
---------
S
-----
A
V
E
A
A
L
E
--
A
A
-
R
L
R
F
R
P
I
I
M
T
S
F
A
F
I
L
G
V
V
P
L
Y
I
---
A
A
GAS
S
---
A
S
Q
R
A
I
G
T
T
V
F
W
G
M
L
V
G
T
L
L
S
V
F
L
V
P
L
F
Y
V
V
V
R
K
F
F
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
HHSearch
45.90
9%
-111
- C2 -
3NE5
-
CUSA_ECOLI
A:
[864-1043]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
L
E
R
A
N
H
K
L
K
L
M
V
P
M
T
L
M
I
I
F
V
L
L
Y
L
A
F
-------------
R
R
V
G
E
A
L
L
I
I
S
S
V
P
F
A
L
V
G
G
I
W
L
L
---
W
W
M
G
F
H
L
S
V
A
T
G
T
G
F
I
A
L
A
G
V
A
A
E
-----------------
F
G
V
V
M
L
M
Y
L
R
H
A
I
E
A
V
P
SLNNPQTFS
E
Q
K
L
D
E
A
L
Y
H
G
A
V
--
L
R
-
V
R
P
---
K
A
M
T
V
A
V
I
I
A
G
L
L
P
I
L
W
---
G
T
---
G
AGS
E
V
M
S
R
I
A
A
P
M
I
G
G
M
I
T
A
P
L
L
S
L
F
I
I
P
A
A
Y
K
L
M
W
L
H
R
H
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
HHSearch
41.51
22%
-160
- C2 -
3AQO
-
SECDF_THET8
A:
[42-94]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
L
R
I
V
L
E
A
-
D
--
V
E
NPT
L
D
D
L
E
K
A
R
T
V
L
E
N
R
I
N
A
L
G
V
AEP--
L
--------
I
-----
Q
I
Q
G
-
Q
K
R
I
V
V
E
L
P
G
L
S
-----------------------------
Q
A
D
Q
D
R
A
L
K
L
I
G
Q
R
A
V
L
E
F
R
I
V
K
E
G
A
T
G
------------
T
T
V
A
Q
I
N
Q
A
L
R
E
N
P
R
L
N
R
E
E
L
E
K
D
L
I
K
P
E
D
L
-------------
G
-
P
P
L
L
T
G
A
D
L
A
D
A
R
A
V
F
D
Q
F
G
R
P
---
Q
V
S
L
T
F
T
P
E
G
A
K
K
F
E
E
V
T
R
Q
N
I
G
K
-----------------
R
L
A
I
V
L
D
G
R
V
Y
T
A
P
V
I
R
---------
Q
A
I
T
G
G
Q
A
V
I
E
G
L
--
S
S
-
V
E
E
---
A
S
E
I
A
L
V
L
R
S
G
S
L
P
V
P
L
---
K
V
---
A
---
E
I
R
A
I
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
41.25
27%
-42
- C2 -
3W9I
-
MEXB_PSEAE
A:
[893-989]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
-
W
S
I
P
F
S
V
M
L
V
V
P
L
G
V
I
G
A
L
L
A
T
---
S
M
R
G
L
S
N
D
V
F
F
Q
V
G
L
L
T
T
I
G
L
S
A
K
-----------------
N
A
I
L
I
V
E
F
A
K
E
L
H
E
Q
G
K
---------
G
-----
I
V
E
A
A
I
E
--
A
C
-
R
M
R
L
R
P
I
V
M
T
S
L
A
F
I
L
G
V
V
P
L
A
I
---
S
T
---
G
---
A
G
S
G
S
Q
H
A
I
G
T
G
V
I
G
G
M
V
T
A
T
V
L
A
I
F
W
V
P
L
F
Y
V
A
V
S
T
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
HHSearch
40.58
11%
-31
- C2 -
2HIY
-
?
A:
[25-72]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
E
----
L
R
Q
E
L
T
N
L
G
L
E----
K
--------
V
-----
E
S
Y
I
N
S
G
N
I
F
F
T
S
I
D
S
------------------------------
K
A
Q
L
V
E
K
L
E
T
F
F
A
V
H
Y
P
F
I
Q
S
F
S
L
L
S
L
E
------------
D
F
E
A
E
L
E
N
L
P
A
W
W
S
R
D
L
A
R
K
D
F
L
F
Y
T
E
G
L
D
V
-------------
D
-
Q
V
I
A
T
V
E
S
L
E
L
K
D
E
V
L
Y
F
G
K
L
G
---
I
F
W
G
K
F
S
E
E
S
Y
S
K
T
A
Y
H
K
Y
L
L
K
V
P
-----------------
F
Y
R
H
I
T
I
R
N
A
K
T
F
D
K
I
G
---------
Q
M
L
K
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
40.12
27%
-49
- C2 -
2V50
-
MEXB_PSEAE
A:
[893-989]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
-
W
S
I
P
F
S
V
M
L
V
V
P
L
G
V
I
G
A
L
L
A
T
---
S
M
R
G
L
S
N
D
V
F
F
Q
V
G
L
L
T
T
I
G
L
S
A
K
-----------------
N
A
I
L
I
V
E
F
A
K
E
L
H
E
Q
G
K
---------
G
-----
I
V
E
A
A
I
E
--
A
C
-
R
M
R
L
R
P
I
V
M
T
S
L
A
F
I
L
G
V
V
P
L
A
I
---
S
T
---
G
---
A
G
S
G
S
Q
H
A
I
G
T
G
V
I
G
G
M
V
T
A
T
V
L
A
I
F
W
V
P
L
F
Y
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
39.34
25%
-42
- C2 -
2PIY
2
CBPB1_PIG
A:
[180-258]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
R
N
N
L
S
S
I
K
A
Y
L
T
I
H
S
Y
S
--------------------
Q
M
I
L
Y
P
Y
S
Y
D
Y
K
L
P
E
N
---------
N
A
E
L
N
N
L
A
K
A
A
V
K
E
L
A
T
-
L
Y
G
---
T
K
Y
T
Y
G
P
G
A
T
T
I
Y
P
A
A
G
---
G
S
---
D
---
D
W
A
Y
D
Q
G
I
K
Y
S
F
T
F
E
L
R
D
K
G
R
Y
G
F
I
L
P
E
S
Q
I
Q
A
T
C
E
E
T
M
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
39.08
25%
-40
- C2 -
2PJ7
2
CBPB1_PIG
A:
[180-258]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
R
N
N
L
S
S
I
K
A
Y
L
T
I
H
S
Y
S
--------------------
Q
M
I
L
Y
P
Y
S
Y
D
Y
K
L
P
E
N
---------
N
A
E
L
N
N
L
A
K
A
A
V
K
E
L
A
T
-
L
Y
G
---
T
K
Y
T
Y
G
P
G
A
T
T
I
Y
P
A
A
G
---
G
S
---
D
---
D
W
A
Y
D
Q
G
I
K
Y
S
F
T
F
E
L
R
D
K
G
R
Y
G
F
I
L
P
E
S
Q
I
Q
A
T
C
E
E
T
M
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
39.02
25%
-43
- C2 -
2PJ2
2
CBPB1_PIG
A:
[180-258]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
R
N
N
L
S
S
I
K
A
Y
L
T
I
H
S
Y
S
--------------------
Q
M
I
L
Y
P
Y
S
Y
D
Y
K
L
P
E
N
---------
N
A
E
L
N
N
L
A
K
A
A
V
K
E
L
A
T
-
L
Y
G
---
T
K
Y
T
Y
G
P
G
A
T
T
I
Y
P
A
A
G
---
G
S
---
D
---
D
W
A
Y
D
Q
G
I
K
Y
S
F
T
F
E
L
R
D
K
G
R
Y
G
F
I
L
P
E
S
Q
I
Q
A
T
C
E
E
T
M
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
38.86
25%
-44
- C2 -
2PJ4
2
CBPB1_PIG
A:
[180-258]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
R
N
N
L
S
S
I
K
A
Y
L
T
I
H
S
Y
S
--------------------
Q
M
I
L
Y
P
Y
S
Y
D
Y
K
L
P
E
N
---------
N
A
E
L
N
N
L
A
K
A
A
V
K
E
L
A
T
-
L
Y
G
---
T
K
Y
T
Y
G
P
G
A
T
T
I
Y
P
A
A
G
---
G
S
---
D
---
D
W
A
Y
D
Q
G
I
K
Y
S
F
T
F
E
L
R
D
K
G
R
Y
G
F
I
L
P
E
S
Q
I
Q
A
T
C
E
E
T
M
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
38.78
25%
-34
- C2 -
2PJ6
2
CBPB1_PIG
A:
[180-258]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
R
N
N
L
S
S
I
K
A
Y
L
T
I
H
S
Y
S
--------------------
Q
M
I
L
Y
P
Y
S
Y
D
Y
K
L
P
E
N
---------
N
A
E
L
N
N
L
A
K
A
A
V
K
E
L
A
T
-
L
Y
G
---
T
K
Y
T
Y
G
P
G
A
T
T
I
Y
P
A
A
G
---
G
S
---
D
---
D
W
A
Y
D
Q
G
I
K
Y
S
F
T
F
E
L
R
D
K
G
R
Y
G
F
I
L
P
E
S
Q
I
Q
A
T
C
E
E
T
M
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
38.73
25%
-41
- C2 -
2PJ0
2
CBPB1_PIG
A:
[180-258]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
R
N
N
L
S
S
I
K
A
Y
L
T
I
H
S
Y
S
--------------------
Q
M
I
L
Y
P
Y
S
Y
D
Y
K
L
P
E
N
---------
N
A
E
L
N
N
L
A
K
A
A
V
K
E
L
A
T
-
L
Y
G
---
T
K
Y
T
Y
G
P
G
A
T
T
I
Y
P
A
A
G
---
G
S
---
D
---
D
W
A
Y
D
Q
G
I
K
Y
S
F
T
F
E
L
R
D
K
G
R
Y
G
F
I
L
P
E
S
Q
I
Q
A
T
C
E
E
T
M
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
38.37
27%
-63
- C2 -
3W9J
-
MEXB_PSEAE
A:
[893-989]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
-
W
S
I
P
F
S
V
M
L
V
V
P
L
G
V
I
G
A
L
L
A
T
---
S
M
R
G
L
S
N
D
V
F
F
Q
V
G
L
L
T
T
I
G
L
S
A
K
-----------------
N
A
I
L
I
V
E
F
A
K
E
L
H
E
Q
G
K
---------
G
-----
I
V
E
A
A
I
E
--
A
C
-
R
M
R
L
R
P
I
V
M
T
S
L
A
F
I
L
G
V
V
P
L
A
I
---
S
T
---
G
---
A
G
S
G
S
Q
H
A
I
G
T
G
V
I
G
G
M
V
T
A
T
V
L
A
I
F
W
V
P
L
F
Y
V
A
V
S
T
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
38.15
25%
-41
- C2 -
2PIZ
2
CBPB1_PIG
A:
[180-258]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
R
N
N
L
S
S
I
K
A
Y
L
T
I
H
S
Y
S
--------------------
Q
M
I
L
Y
P
Y
S
Y
D
Y
K
L
P
E
N
---------
N
A
E
L
N
N
L
A
K
A
A
V
K
E
L
A
T
-
L
Y
G
---
T
K
Y
T
Y
G
P
G
A
T
T
I
Y
P
A
A
G
---
G
S
---
D
---
D
W
A
Y
D
Q
G
I
K
Y
S
F
T
F
E
L
R
D
K
G
R
Y
G
F
I
L
P
E
S
Q
I
Q
A
T
C
E
E
T
M
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------