@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Wbm0188: (2015-11-29 )
MSEARNLILAAILSILIIVSWRIIYDNFLNAEQDHPLIENIEHIESFNDLAPVIHQSRSEIINSTREQRINLTNNMVKGSISLKGARFDDLILTNYCLEPDPSSPQVVLLSPAESKDVYFAEFGWLDPNGKTKVPDSKTFWQAEKTELTNQKAVNLFWNNENGIVFRMKVSLDNNYMFKVEQIVENNTKDNVVLVPYGKINRKRDNINESYWISHEGILGAFDNKLEEWTYKNVAKKHLIKASTSKKNWFGFADKYWLTAIIPEKFDKTNVSIKHTNANNVDKFQVDFVKPYKNILPGTSASNVNYFFAGAKKLNLLDYYKSTLNIPLFDKAVDFGVLYFITKPVFLLLEYFNFVLKNFGLAILLLTLVIKLLMLPLSNRSYVSMFKMKSLQPEVARIKELYKNDSLKQHKETIALFKKNNVNPMSSILPILVQIPVFFALYKVLFVTIEMRHAPFCLWIKDLSTSDPTNIFTLFGLFNYNFPISIGILPIILGITMIIQQKIGEKGQTNKDDIQANVMKFFPYISIFIFSSFPAGLVIYWIFSNVITLIQQSLIKLFLTRKLGINVENTNS
Atome Classification :
(20 SA)
.........10........20........30........40......--..50..---......60........70........80--........90........100...-....110.......120.......130-......-..140...-----.-...-----150...-----....---160....----...170-...-.-.....180.......190....--------------------------...200.----..-.-.--..210.......220---.-......-230....----...240.......250........260...-....270......----------.280....------...290..----.....300-.......310....-..--.320.......330.......340.......350.....-..360---........370.......380.......390.......400-------....-------..-------.410.......420.....-----------..430.......440.......450....--------...460.......470.......480.......490-...-------------....500.......510.--......520-------........530.......540.......550.......560.......570-----------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MS
E
A
R
N
L
I
L
A
A
I
L
S
I
L
I
I
V
S
W
R
I
I
Y
D
NFLNAEQDH
P
L
I
E
N
I
E
H
I
E
S
F
--
N
D
L
A
P
V
---
I
H
Q
S
R
S
E
I
I
N
S
T
R
E
Q
R
I
NLTN
N
M
V
K
G
S
I
--
S
LKGARF
D
D
L
I
L
T
N
YCLEPDPSSP-
Q
V
V
L
LSPAESK
D
V
Y
F
A
E
FGWLDPNG-K-TKVPDS-KTFW
Q
A
E
K
-----T-ELT-----NQ
K
A
V
N
-----
L
F
W
N---NEN
G
I
V
F
----
R
M
K
V
---SLD-N-
N
Y
M
F
K
V
E
Q
I
V
ENNTKD
N
V
V
L
V
P--------------------------YGKINRK----RD-N-I--NE
S
Y
W
ISHEGI
L
G
A
F
---D-
N
K
L
E
E
W
-
T
Y
K
N
V
A
K
----
K
H
L
I
KASTSKKN
W
F
G-FA
D
K
Y
W
L
T
A
IIPEK-FDKT
N
V
S
I
K
HTNA----------NNV
D
K
F
Q
V
------
D
F
V
K
P
Y
K
N
----ILPGTSAS-N
V
N
Y
F
F
AGAKK
L
N
L
-
L
D
--
Y
Y
K
S
TLNIPLFDKAVD
F
G
V
L
Y
F
I
T
K
P
V
F
L
L
L
E
Y
F
N
F
V
L
K
-NF
G
L
----
A
I
L
L
L
T
L
V
I
K
L
L
MLPLSN
R
S
Y
V
S
M
F
K
M
KSL
Q
P
E
V
A
R
I
K
E
L
Y-------KND
S
-------
L
K
-------
Q
H
K
E
T
I
A
L
FKKNNVN
P
M
S
S
-----------
I
L
P
I
L
V
Q
I
P
V
F
F
A
L
Y
K
V
L
F
V
T
I
EMRHA
P
F
--------
C
L
W
I
KDLSTSDPT
N
I
F
T
L
F
G
LFNYNF
P
I
S
I
G
I
L
P
I
I
-
L
G
I
-------------
T
M
I
I
Q
Q
K
IGEKGQT
N
K
D
D
--
I
Q
A
N
V
M
K
F
--------
F
P
Y
I
S
I
F
I
FSSFPA
G
L
V
I
Y
W
I
F
S
N
V
I
T
L
I
Q
Q
S
L
I
K
L
F
L
T
R
KLG
I
N
VENTNS-----------------------
1
PsiBlast_PDB
93.62
27%
-85
- C3 -
3WVF
-
YIDC_ECOUT
A:
[56-528]
---------------------------------------------------------------------
G
Q
G
K
L
I
S
V
K
T
D
V
L
D
L
T
I
--
N
T
R
G
G
D
V
E
Q
A
L
L
P
A
Y
P
K
E
L
N
S
T
Q
P
F
Q
L
L
E
T
S
P
---
Q
F
I
Y
Q
A
Q
S
G
L
T
G
R
D
G
-
P
-
D
N
P
A
N
G
P
R
P
L
Y
N
V
E
K
D
A
Y
V
L
A
-
E
G
Q
-----
N
E
L
Q
V
P
-----
M
T
Y
T
---
D
A
A
G
N
T
F
----
T
K
T
F
---
V
L
K
R
G
-
D
Y
A
V
N
V
N
Y
N
V
Q
N
A
G
E
K
P
L
E
I
S
T
--------------------------
F
G
Q
L
K
Q
S
ITLP---------------
H
T
F
R
G
A
A
Y
S
T
P
D
-
E
K
Y
E
K
Y
-
K
F
D
T
I
A
D
----
N
E
N
L
N
I
S
-
S
K
G
G
W
V
A
-
M
L
Q
Q
Y
F
A
T
A
W
I
P
H
N
--
D
G
T
N
N
F
Y
T
A
N
L
G
----------
N
G
I
A
A
--
I
------
G
Y
K
S
Q
P
V
L
----
V
Q
P
G
Q
T
G
A
-
M
N
S
T
L
W
V
G
P
E
I
Q
D
--------
K
M
A
A
V
A
P
H
L
D
L
T
V
D
Y
G
W
L
W
F
I
S
Q
P
L
F
K
L
L
K
W
I
H
S
F
V
G
-
N
W
G
F
----
S
I
I
I
I
T
F
I
V
R
G
I
M
Y
P
L
T
K
A
Q
Y
T
S
M
A
K
M
R
M
L
Q
P
K
I
Q
A
M
R
E
R
L
-------
G
D
D
K
-------
Q
R
-------
I
S
Q
E
M
M
A
L
Y
K
A
E
K
V
N
P
L
G
G
-----------
C
F
P
L
L
I
Q
M
P
I
F
L
A
L
Y
Y
M
L
M
G
S
V
E
L
R
Q
A
P
F
--------
A
L
W
I
H
D
L
S
A
Q
D
P
Y
Y
-----------------
I
L
P
I
L
-
M
G
V
-------------
T
M
F
F
I
Q
-----------------
K
I
M
T
F
--------
M
P
V
I
F
T
V
F
F
L
W
F
P
S
G
L
V
L
Y
Y
I
V
S
N
L
V
T
I
I
Q
Q
-------------------------------------------
14
HHSearch
92.04
26%
-88
- C3 -
3WVF
-
YIDC_ECOUT
A:
[56-528]
---------------------------------------------------------------------
G
Q
G
K
L
I
S
V
K
T
D
V
L
D
L
T
I
--
N
T
R
G
G
D
V
E
Q
A
L
L
P
A
Y
P
K
E
L
N
S
-
T
Q
-
P
F
Q
L
L
E
T
S
P
-
Q
F
I
Y
Q
A
Q
S
G
L
T
G
R
D
G
P
D
-
N
P
A
N
G
P
-
R
P
L
Y
N
V
E
K
-----
D
A
Y
V
L
A
EGQ-
N
E
L
Q
V
P
-----
M
T
Y
T
---
D
A
A
G
N
T
F
----
T
K
T
F
---
V
L
K
R
G
-
D
Y
A
V
N
V
N
Y
N
V
Q
N
A
G
E
K
P
L
E
I
S
T
--------------------------
F
G
Q
L
K
Q
S
----
I
T
-
L
P--------
H
T
F
R
G
A
A
Y
S
T
---
P
D
E
K
Y
E
K
Y
-
K
F
D
T
I
A
D
----
N
E
-
N
L
N
I
S
S
K
G
G
W
V
A
-
M
L
Q
Q
Y
F
A
T
A
W
I
P
H
N
-
D
G
T
N
N
F
Y
T
A
N
--
L
-----------
G
N
G
I
A
A
I
------
G
Y
K
S
Q
P
V
L
----
V
Q
P
G
Q
T
G
A
-
M
N
S
T
L
W
V
G
P
E
I
Q
D
K
-
M
A
--
A
V
A
-----
P
H
L
D
L
T
V
D
Y
G
W
L
W
F
I
S
Q
P
L
F
K
L
L
K
W
I
H
S
F
V
G
-
N
W
G
F
----
S
I
I
I
I
T
F
I
V
R
G
I
M
Y
P
L
T
K
A
Q
Y
T
S
M
A
K
M
R
M
L
Q
P
K
I
Q
A
M
R
E
R
L
-------
G
D
D
K
-------
Q
R
-------
I
S
Q
E
M
M
A
L
Y
K
A
E
K
V
N
P
L
G
G
-----------
C
F
P
L
L
I
Q
M
P
I
F
L
A
L
Y
Y
M
L
M
G
S
V
E
L
R
Q
A
P
F
--------
A
L
W
I
H
D
L
S
A
Q
D
P
Y
Y
I
-----------------
L
P
I
L
-
M
G
V
-------------
T
M
F
F
I
Q
-----------------
K
I
M
T
F
--------
M
P
V
I
F
T
V
F
F
L
W
F
P
S
G
L
V
L
Y
Y
I
V
S
N
L
V
T
I
I
Q
Q
-------------------------------------------
13
PsiBlast_PDB
65.40
19%
-34
- C3 -
3BS6
11
YIDC_ECOLI
A:
[4-274]
------------------------------------------------------------------------
K
L
I
S
V
K
T
D
V
L
D
L
T
I
--
N
T
R
G
G
D
V
E
Q
A
L
L
P
A
Y
P
K
E
L
N
S
T
Q
P
F
Q
L
L
E
T
S
P
---
Q
F
I
Y
Q
A
Q
S
G
L
T
G
R
D
G
-
P
-
D
N
P
A
N
G
P
R
P
L
Y
N
V
E
K
D
A
Y
V
L
A
-
E
G
Q
-----
N
E
L
Q
V
P
-----
M
T
Y
T
---
D
A
A
G
N
T
F
----
T
K
T
F
---
V
L
K
R
G
-
D
Y
A
V
N
V
N
Y
N
V
Q
N
A
G
E
K
P
L
E
I
S
S
--------------------------
F
G
Q
L
K
Q
S
ITLP----------------
T
F
R
G
A
A
Y
S
T
P
D
-
E
K
Y
E
K
Y
-
K
F
D
T
I
A
D
----
N
E
N
L
N
I
S
-
S
K
G
G
W
V
A
-
M
L
Q
Q
Y
F
A
T
A
W
I
P
H
N
--
D
G
T
N
N
F
Y
T
A
N
L
G
----------
N
G
I
A
A
--
I
------
G
Y
K
S
Q
P
V
L
----
V
Q
P
G
Q
T
G
A
-
M
N
S
T
L
W
V
G
P
E
I
Q
D
--------
K
M
A
A
V
A
P
H
L
D
L
T
V
D
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
HHSearch
64.22
18%
-36
- C3 -
3BS6
11
YIDC_ECOLI
A:
[4-274]
------------------------------------------------------------------------
K
L
I
S
V
K
T
D
V
L
D
L
T
I
--
N
T
R
G
G
D
V
E
Q
A
L
L
P
A
Y
P
K
E
L
N
-
S
T
Q
-
P
F
Q
L
L
E
T
S
P
-
Q
F
I
Y
Q
A
Q
S
G
L
T
G
R
D
G
P
D
-
N
P
A
N
G
P
-
R
P
L
Y
N
V
E
K
-----
D
A
Y
V
L
A
EGQ-
N
E
L
Q
V
P
-----
M
T
Y
T
---
D
A
A
G
N
T
F
----
T
K
T
F
---
V
L
K
R
G
-
D
Y
A
V
N
V
N
Y
N
V
Q
N
A
G
E
K
P
L
E
I
S
S
--------------------------
F
G
Q
L
K
Q
S
----
I
T
L
P
----------
T
F
R
G
A
A
Y
S
T
---
P
D
E
K
Y
E
K
Y
-
K
F
D
T
I
A
D
----
N
-
E
N
L
N
I
S
S
K
G
G
W
V
A
-
M
L
Q
Q
Y
F
A
T
A
W
I
P
H
N
-
D
G
T
N
N
F
Y
--
T
A
N
L
-----------
G
N
G
I
A
A
I
------
G
Y
K
S
Q
P
V
L
----
V
Q
P
G
Q
T
G
A
-
M
N
S
T
L
W
V
G
P
E
I
Q
D
K
-
M
A
--
A
V
A
-----
P
H
L
D
L
T
V
D
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
61.82
29%
-98
- C2 -
4UTQ
1
YIDC_ECOLI
A:
[419-531]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
L
G
G
-----------
C
F
P
L
L
I
Q
M
P
I
F
L
A
L
Y
Y
M
Y
--------------------------------------------------
I
L
P
I
L
-
M
G
V
-------------
T
M
F
F
I
Q
K
I
-----------------
M
T
F
--------
M
P
V
I
F
T
V
F
F
L
W
F
P
S
G
L
V
L
Y
Y
I
V
S
N
L
V
T
I
I
Q
Q
Q
L
I
Y
---------------------------------------
3
PsiBlast_PDB
61.57
28%
-140
- C2 -
3WO6
5
YIDC2_BACHD
A:
[16-232]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
F
V
Y
P
M
S
W
L
I
T
T
V
A
N
L
L
N
G
-
S
Y
G
L
----
S
I
I
I
V
T
I
L
I
R
L
A
L
L
P
L
T
L
K
Q
Q
K
S
M
R
A
M
Q
V
I
R
P
E
M
E
A
I
Q
K
K
Y
-------
K
E
K
A
-------
S
K
D
P
K
V
Q
Q
E
M
Q
K
E
L
L
G
L
Y
Q
K
H
G
V
N
P
M
A
G
-----------
C
L
P
L
F
I
Q
L
P
I
L
M
A
F
Y
F
A
I
M
R
T
E
E
I
R
Y
H
T
F
---------
L
W
F
-
D
L
G
Q
P
D
------------
Y
I
L
P
F
V
A
G
I
T
T
Y
F
Q
F
K
M
-------------
T
M
S
H
----------------------
Q
M
Q
M
K
V
M
L
Y
V
M
P
V
M
I
I
I
A
G
L
S
L
P
S
A
L
S
L
Y
W
V
I
G
N
I
F
M
I
I
Q
T
Y
------------------------------------------
15
HHSearch
61.07
31%
-135
- C2 -
3WO6
5
YIDC2_BACHD
A:
[11-232]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
I
W
N
H
F
F
V
Y
P
M
S
W
L
I
T
T
V
A
N
L
L
N
G
S
Y
G
L
----
S
I
I
I
V
T
I
L
I
R
L
A
L
L
P
L
T
L
K
Q
Q
K
S
M
R
A
M
Q
V
I
R
P
E
M
E
A
I
Q
K
K
Y
-------
K
E
K
A
SKD
P
K
V
Q
Q
E
-------
M
Q
K
E
L
L
G
L
Y
Q
K
H
G
V
N
P
M
A
G
-----------
C
L
P
L
F
I
Q
L
P
I
L
M
A
F
Y
F
A
I
M
R
T
E
E
I
R
Y
H
T
F
---------
L
W
F
-
D
L
G
--
Q
P
D
Y
I
-----------------
L
P
F
V
-
A
G
I
-------------
T
T
Y
F
Q
F
K
M
T
M
S
H
------Q
M
Q
M
K
V
M
L
Y
V
--------
M
P
V
M
I
I
I
A
G
L
S
L
P
S
A
L
S
L
Y
W
V
I
G
N
I
F
M
I
I
Q
T
Y
------------------------------------------
24
Fugue
61.03
29%
-125
- C2 -
3WO6
6
YIDC2_BACHD
A:
[1-232]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
Q
D
P
I
T
S
E
S
E
G
I
W
N
H
F
F
V
Y
P
M
S
W
L
I
T
T
V
A
N
L
L
N
G
-
S
Y
G
L
----
S
I
I
I
V
T
I
L
I
R
L
A
L
L
P
L
T
L
K
Q
Q
K
S
M
R
A
M
Q
V
I
R
P
E
M
E
A
I
Q
K
K
Y
K
E
KASKD
P
K
V
Q
-------
Q
E
-------
M
Q
K
E
L
L
G
L
Y
Q
K
H
G
V
N
P
M
A
G
-----------
C
L
P
L
F
I
Q
L
P
I
L
M
A
F
Y
F
A
I
M
R
T
E
E
I
R
Y
H
T
F
---------
L
W
F
D
-
L
G
Q
P
D
Y
-------------------
I
L
P
F
V
-
A
G
I
-------------
T
T
Y
F
Q
F
K
M
T
M
S
----
H
Q
M
--
Q
M
K
V
M
L
Y
V
--------
M
P
V
M
I
I
I
A
G
L
S
L
P
S
A
L
S
L
Y
W
V
I
G
N
I
F
M
I
I
Q
T
Y
------------------------------------------
2
PsiBlast_PDB
60.19
28%
-141
- C2 -
3WO7
-
YIDC2_BACHD
A:
[16-234]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
F
V
Y
P
M
S
W
L
I
T
T
V
A
N
L
L
N
G
-
S
Y
G
L
----
S
I
I
I
V
T
I
L
I
R
L
A
L
L
P
L
T
L
K
Q
Q
K
S
M
R
A
M
Q
V
I
R
P
E
M
E
A
I
Q
K
K
Y
-------
K
E
K
A
-------
S
K
D
P
K
V
Q
Q
E
M
Q
K
E
L
L
G
L
Y
Q
K
H
G
V
N
P
M
A
G
-----------
C
L
P
L
F
I
Q
L
P
I
L
M
A
F
Y
F
A
I
M
R
T
E
E
I
R
Y
H
T
F
---------
L
W
F
-
D
L
G
Q
P
D
------------
Y
I
L
P
F
V
A
G
I
T
T
Y
F
Q
F
K
M
-------------
T
M
S
H
------------------------Q
M
K
V
M
L
Y
V
M
P
V
M
I
I
I
A
G
L
S
L
P
S
A
L
S
L
Y
W
V
I
G
N
I
F
M
I
I
Q
T
Y
F
I
V
V
K
A
P
P
L
E
V
L
E
S
S
G
--------------------------
26
Fugue
55.33
13%
-57
- C2 -
3ZVR
3
DYN1_RAT
A:
[25-763]
G
M
E
D
L
I
P
L
V
N
R
L
Q
D
A
F
S
A
I
G
Q
N
A
D
L
D
L
P
Q
I
A
V
V
G
G
Q
S
A
G
K
S
S
V
L
E
N
F
V
G
R
D
F
L
P
R
GSG
I
V
T
R
R
P
L
V
L
Q
L
V
N
S
T
T
E
Y
A
E
F
L
H
C
K
G
K
K
FT
D
F
E
E
V
R
L
E
I
E
A
E
T
D
R
V
T
G
T
N
K
G
I
S
-
P
V
P
I
N
L
R
V
Y
S
P
H
V
L
--
N
L
T
L
V
D
L
P
G
-
M
-
T
K
V
P
V
G
-
D
---
Q
P
P
D
-----
I
-
E
F
Q
-----
I
R
D
M
L
M
-----
Q
F
V
T
---
K
E
N
C
L
I
L
----
A
V
S
P
ANS
D
L
A
-
N
-
S
D
A
L
K
I
A
K
E
V
D
P
Q
G
Q
R
T
I
G
V
I
T
KLDLMDEGTDA
R
D
V
L
E
NKLLPLRR
G
Y
I
G
V
V
N
R
S
----
Q
K
-
D
-
I
--
D
G
K
--
K
D
I
T
A
A
L
A
A
E
---
R
-
K
F
F
L
S
H
P
S
Y
R
H
L
A
D
RMG
T
P
Y
L
Q
K
V
L
N
Q
Q
L
T
N
H
I
-
R
D
T
L
P
G
L
R
N
K
L
Q
S
Q
-
L
L
S
I
E
K
E
V
D
E
Y
K
N
F
R
PDDPAR
K
T
K
A
L
L
Q
M
V
Q
------
Q
F
A
V
D
F
E
K
----
R
I
E
G
L
S
---------
G
G
A
R
I
N
R
I
-
F
H
E
R
F
P
F
E
L
V
K
M
E
F
D
E
K
E
L
R
R
E
I
S
Y
A
I
K
N
I
H
F
T
P
D
L
A
F
E
A
T
V
K
-
K
Q
V
Q
K
L
K
E
P
S
I
K
C
V
D
M
V
V
S
E
L
T
S
T
I
R
K
C
S
E
K
L
Q
Q
Y
P
R
L
R
E
E
M
E
R
I
V
T
T
H
-------
I
R
E
R
-------
E
G
-------
R
T
K
E
Q
V
M
L
L
I
D
I
E
L
A
Y
M
N
T
NHEDFIGFILV
I
R
K
G
W
L
T
I
N
N
I
G
I
M
S
K
E
Y
W
F
V
L
T
A
E
N
L
S
W
YKDDEEKE
K
K
Y
M
L
S
V
D
N
L
K
L
R
D
V
K
H
I
F
A
L
F
N
T
E
Q
R
N
V
Y
K
D
Y
R
Q
L
-
E
L
A
C
E
T
Q
E
E
V
D
S
W
K
A
S
F
L
R
A
G
V
Y
P
E
P
Q
L
E
R
Q
V
E
T
--
I
R
N
L
V
D
S
Y
--------
M
A
I
V
N
K
T
V
R
D
L
M
P
K
T
I
M
H
L
M
I
N
N
T
K
E
F
I
F
S
E
L
L
A
N
L
Y
S
C
G
D
Q
N
T
L
M
E
E
S
A
E
Q
A
Q
R
R
D
E
M
L
R
M
Y
H
A
L
K
E
A
L
S
I
I
G
16
HHSearch
54.64
17%
5
- C3 -
3BLC
-
YIDC_ECOLI
A:
[57-346]
----------------------------------------------------------------------
Q
G
K
L
I
S
V
K
T
D
V
L
D
L
T
I
--
N
T
R
G
G
D
V
E
Q
A
L
L
P
A
Y
P
K
E
L
N
S
-
T
Q
-
P
F
Q
L
L
E
T
S
P
-
Q
F
I
Y
Q
A
Q
S
G
L
T
G
R
D
G
P
D
-
N
P
A
N
G
P
-
R
P
L
Y
N
V
E
K
-----
D
A
Y
V
L
AEGQ-
N
E
L
Q
V
P
-----
M
T
Y
T
---
D
A
A
G
N
T
F
----
T
K
T
F
---
V
L
K
R
G
-
D
Y
A
V
N
V
N
Y
N
V
Q
N
A
G
E
K
P
L
E
I
S
S
--------------------------
F
G
Q
L
K
Q
S
----
I
T
L
P
-
P
HL------
T
F
R
G
A
A
Y
S
T
---
P
D
A
A
Y
A
A
Y
-
A
F
D
T
I
A
D
----
N
-
E
N
L
N
I
S
S
K
G
G
W
V
A
-
M
L
Q
Q
Y
F
A
T
A
W
I
P
H
N
-
D
G
T
N
N
F
Y
T
A
N
--
L
-----------
G
N
G
I
A
A
I
------
G
Y
K
S
Q
P
V
L
----
V
Q
P
G
Q
T
G
A
-
M
N
S
T
L
W
V
G
P
E
I
Q
D
K
-
M
A
--
A
V
A
-----
P
H
L
D
L
T
V
D
Y
G
W
L
W
F
I
S
Q
P
L
L
V
P
R
G
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
Fugue
54.11
17%
10
- C3 -
3BLC
-
YIDC_ECOLI
A:
[57-346]
----------------------------------------------------------------------
Q
G
K
L
I
S
V
K
T
D
V
L
D
L
T
I
--
N
T
R
G
G
D
V
E
Q
A
L
L
P
A
Y
P
K
E
L
N
S
T
Q
P
-
F
Q
L
L
E
T
--
S
P
Q
F
I
Y
Q
A
Q
S
G
L
T
G
R
D
G
-
P
D
N
P
A
N
G
P
-
R
P
L
Y
N
V
E
K
-----
D
-
A
Y
V
LAEGQ
N
E
L
Q
V
P
M
----
T
Y
T
D
---
A
A
G
N
T
F
T
----
K
T
F
V
---
L
K
R
-
G
-
D
Y
A
V
N
V
N
Y
N
V
Q
N
A
G
E
K
P
L
E
I
S
S
--------------------------
F
G
Q
L
K
Q
S
----
I
T
-
L
-
P
--
P
H
L
T
F
--
R
G
A
A
Y
S
T
P
---
D
-
A
A
Y
A
A
Y
-
A
F
D
T
I
A
D
----
N
E
N
L
N
I
S
S
-
K
G
G
W
V
A
M
L
Q
-
Q
Y
F
A
T
A
W
I
P
H
N
-
D
G
T
N
N
F
Y
T
A
N
L
G
N
----------
G
---
I
A
A
I
------
G
Y
K
S
Q
P
V
L
----
V
Q
P
G
Q
T
G
A
M
N
-
S
T
L
W
V
G
P
E
I
Q
D
K
M
A
A
--------
V
A
P
H
L
D
L
T
V
D
Y
G
W
L
W
F
I
S
Q
P
L
L
V
P
R
G
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
39.02
24%
-4
* C4 *
3C75
-
DHMH_PARVE
H:
[203-315]
-----------------------------------------------------------------------------------
G
V
V
--
D
L
E
G
K
T
F
D
R
M
L
D
V
P
D
C
Y
H
I
F
P
A
S
P
-
T
V
F
Y
M
N
---
C
R
D
G
S
L
A
R
V
D
F
A
D
--
G
-
E
-
T
K
V
T
N
T
-
E
V
F
-
H
T
E
D
-----
E
-
L
L
I
-----
N
H
P
A
F
S
LRSGR
L
V
W
P
---
T
Y
T
G
K
I
F
----
Q
A
D
L
---
T
A
E
-
G
A
T
F
R
A
P
I
E
A
L
T
E
A
E
R
A
D
D
W
R
P
G
G
--------------------------
W
Q
Q
T
A
Y
H
----
R
Q
-
S
-
D
--
R
I
Y
L
L
V
D
Q
R
D
E
W
K
H
K
---
A
-
A
S
R
F
V
V
-
V
L
N
A
E
T
G
----
E
R
I
N
K
I
E
L
G
H
E
I
D
S
I
-
N
V
S
Q
D
A
E
P
L
L
Y
A
L
S
-
A
G
T
Q
T
L
H
I
Y
D
A
A
T
----------
G
E
E
L
R
S
V
D
------
Q
L
G
R
G
P
Q
I
----
I
T
T
H
D
M
D
S
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
34.95
25%
52
- C3 -
3BLC
-
YIDC_ECOLI
A:
[247-342]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
S
K
G
G
W
V
A
-
M
L
Q
Q
Y
F
A
T
A
W
I
P
H
N
--
D
G
T
N
N
F
Y
T
A
N
L
G
----------
N
G
I
A
A
I
G
------------
Y
K
S
Q
P
V
L
V
Q
P
G
Q
T
G
A
-
M
N
S
T
L
W
V
G
P
E
I
Q
D
--------
K
M
A
A
V
A
P
H
L
D
L
T
V
D
Y
G
W
L
W
F
I
S
Q
P
L
L
V
P
R
G
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
32.05
26%
43
- C4 -
3R8Y
-
DAPH_BACAN
A:
[23-82]
----------------------------------------------------------------------------------------------------------------------------------------------------
K
V
Y
I
K
G
D
L
-----
K
-
E
V
T
-----
F
P
E
T
V
Q
-----
A
F
V
N
---
K
K
S
G
V
L
F
GE
W
S
E
I
K
T
---
I
L
D
-
E
-
N
S
K
Y
I
V
D
Y
V
V
E
N
D
R
R
N
S
A
I
P
M
L
--------------------------
D
L
K
G
I
K
A
----
R
I
-
E
-
P
--
G
A
I
I
R
D
H
V
E
I
G
D
N
A
V
---
I
-
M
M
N
A
T
I
-
N
I
G
A
V
I
G
----
E
G
S
M
I
D
M
N
A
V
L
G
G
R
A
-
T
V
G
K
N
C
H
V
G
A
G
A
V
L
-
A
G
V
I
E
P
P
S
A
K
P
V
I
----------
V
E
D
D
V
V
I
G
------
A
N
V
V
V
L
E
G
----
V
T
V
G
K
G
A
V
-
V
A
A
G
A
V
V
T
E
D
V
P
P
Y
-
T
V
--
V
A
G
T
P
A
R
V
I
K
E
I
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
30.89
30%
129
- C2 -
2HQ8
2
LBP_RENRE
A:
[114-178]
--------------------------------------------------------------------------------------------------------------------------------------
D
K
D
G
-
Y
-
V
S
L
P
E
F
-
K
A
F
L
Q
A
V
G
-----
P
-
D
L
T
-----
D
D
K
A
I
T
-----
C
F
N
T
L
DF
N
K
N
G
Q
I
S
----
R
D
E
F
---
L
V
T
V
N
-
D
F
L
F
G
L
E
E
T
A
L
A
N
A
F
Y
G
D
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
30.20
27%
33
* C1 *
3FPC
4
ADH1_ENTHI (first)
A:
[196-295]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
V
G
S
R
K
H
C
C
D
-
I
A
L
E
Y
G
A
T
D
I
I
N
Y
K
N
G
D
I
V
E
Q
I
L
K
A
T
D
G
----------
K
G
V
D
K
V
V
I
AGGDVH
T
F
A
Q
A
V
K
M
----
I
K
P
G
S
D
I
G
-
N
V
N
Y
L
G
E
G
----
D
N
-
I
D
--
I
P
R
S
E
W
G
V
G
M
G
H
K
H
I
H
G
G
L
C
P
G
G
R
L
R
M
E
R
L
I
D
L
V
F
Y
K
R
V
-
D
P
S
K
----
L
V
T
H
V
F
R
G
F
D
N
I
E
K
A
F
M
L
M
K
D
K
P
K
D
L
I
K
P
V
V
I
L
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
29.98
30%
116
- C2 -
2HPS
1
LBP_RENRE
A:
[114-178]
--------------------------------------------------------------------------------------------------------------------------------------
D
K
D
G
-
Y
-
V
S
L
P
E
F
-
K
A
F
L
Q
A
V
G
-----
P
-
D
L
T
-----
D
D
K
A
I
T
-----
C
F
N
T
L
DF
N
K
N
G
Q
I
S
----
R
D
E
F
---
L
V
T
V
N
-
D
F
L
F
G
L
E
E
T
A
L
A
N
A
F
Y
G
D
L
V
D
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
Fugue
27.80
21%
222
- C2 -
4C7N
1
A:
[2-48]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
S
V
D
Y
I
R
K
L
Q
R
E
Q
Q
R
A
K
E
L
E
-------
N
R
Q
K
-------
K
L
-------
E
H
A
N
R
H
L
L
L
R
I
Q
E
L
E
M
Q
A
R
-----------
A
H
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
25.80
32%
81
- C1 -
2OUI
3
ADH1_ENTHI
A:
[196-271]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
V
G
S
R
K
H
C
C
D
-
I
A
L
E
Y
G
A
T
D
I
I
N
Y
K
N
G
D
I
V
E
Q
I
L
K
A
T
D
G
----------
K
G
V
D
K
V
V
I
AGGDVH
T
F
A
Q
A
V
K
M
----
I
K
P
G
S
D
I
G
-
N
V
N
Y
L
G
E
G
D
N
I
P
I
P
-
R
S
--
E
W
G
V
G
M
G
H
K
H
I
H
G
G
L
T
P
G
G
R
V
R
M
E
K
L
A
S
L
I
S
T
G
K
L
D
T
S
K
-
L
I
T
H
----
R
F
E
G
L
E
K
V
E
D
A
L
M
L
M
K
N
K
P
A
D
L
I
K
P
V
V
R
I
H
Y
D
D
E
D
T
L
H
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------