@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Wbm0194: (2015-11-29 )
MDYIDIIKSRLLLSDIVGKKVRLTKRGDSFVGFCPFHSEKTPSFLVSNTKGSYHCFGCSAHGDVFNFISQTEGLSFKEALERLASVVGVELPKTLNLAKENGELFSTLNLAASWFVQKNQGIIAYLKQRKISPKIIDKFKVGYAPSSGLKEYLNSLGIEDKILIDVGLINKNSRDYFCNRLIFPIYNIAGKVIGFGGRALSSKQQPKYLNSPESQLFKKRENLYGLNFALSEIHKKQHVFVVEGYMDVIALHQTGISNIVAPLGTAISAEQIKSLWKFAKEISICMDGDSAGRNAAIRVAELVLPILEPGYTLKFVTLPTDKDPYDVCNELEHKKETVLSALDHSTKLHSEYLWHYIIGSNLQNYEKLAPEKYSILERKFMEYVNAIGNSSIRRYYRDYFYDKASELRNSFKKQVFNNKTRATKSEYLYNKSPELIEAEQNQAIILRITLEFPEILNHPIYFEQFSHFEFTNVKIKRLQQHIINVANNGSELNKEVLLQELEQFNVDGTIKLIFEKTSILNSQLNNGKSAKTVWNNIVLRGELNVLQRERIEARLGGDFGLEERLIEQIEQIESNIREMQMEFIQK
Atome Classification :
(20 SA)
-----.........10........20........30........40........50........60........70........80........90........--100.......110.....---.-----.120----....-----.....130.......140.....--.--.150.......160-.........170--.--------..-----.....180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570.......580....
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-----M
D
Y
I
D
I
I
K
S
R
L
L
L
S
D
IVGK
K
V
R
L
TKRGDS
F
V
G
FCPFHSEKTP
S
F
L
V
SNTKG
S
Y
H
C
F
GCSAH
G
D
V
F
N
F
I
S
QTEGL
S
F
K
E
A
L
E
R
L
A
S
V
VGVELP
K
T
L
N
L
A
K--ENG
E
L
F
S
T
L
N
L
A
A
S
W
F
V
Q---K-----NQ------
G
I
I
A
-----
Y
L
K
QRKIS
P
K
I
I
D
K
FKVGYAP
S
S
--
G
--
L
K
E
Y
L
N
SLGIE
D
---
K
I
L
I
D
V
G
LINK---N--------
S
R
-----
D
Y
F
C
N
R
L
I
F
P
I
Y
N
I
A
G
K
V
IGFGGRALSSKQQPKYLNS
P
E
S
Q
L
F
K
K
R
E
NLYG
L
N
F
A
L
S
E
IHKK
Q
H
V
F
V
VEG
Y
M
D
V
I
A
L
H
QT
G
I
S
N
I
V
A
P
LGTAI
S
A
E
Q
I
K
S
L
W
K
F
A
K
E
I
S
I
C
MDGDSAGR
N
A
A
I
R
V
A
E
L
V
L
P
I
LEPG
Y
T
L
K
F
V
TLPTDK
D
P
Y
D
V
C
N
E
L
E
H
K
K
E
T
V
L
S
A
LDHS
T
K
L
H
S
E
Y
L
W
H
Y
I
IGS
N
L
Q
N
Y
E
K
LA
P
E
K
Y
S
I
L
E
R
K
F
M
E
Y
V
N
A
IG
N
S
S
I
R
R
Y
Y
R
D
Y
F
Y
D
K
A
S
E
L
R
N
S
F
K
K
Q
V
FNNKTRATKSEYLYNKSPE
L
I
EAEQN
Q
A
I
I
L
R
I
T
LE
F
P
E
ILNHP
I
Y
F
E
QFSHFEF
T
N
V
K
I
K
R
L
Q
Q
H
I
I
N
VANN
G
S
E
L
N
K
E
V
L
L
Q
E
L
E
Q
FNVD
G
T
I
K
L
I
F
E
K
T
S
I
L
N
S
QLNNGK
S
A
K
T
V
W
N
N
I
V
L
RG
E
L
N
V
L
Q
R
E
R
I
E
A
RLGGDF
G
L
E
E
R
L
I
E
Q
I
E
Q
I
E
S
N
I
R
E
M
Q
M
E
F
IQK
17
HHSearch
92.84
34%
-91
- C4 -
2AU3
1
DNAG_AQUAE
A:
[4-405]
-----
S
S
D
I
D
E
L
R
R
E
I
D
I
V
D
V
I
S
E
Y
L
N
L
E
K
V
G
S
N
Y
R
T
N
C
P
F
H
P
D
D
T
P
S
F
Y
V
S
P
S
K
Q
I
F
K
C
F
G
C
G
V
G
G
D
A
I
K
F
V
S
L
Y
E
D
I
S
Y
F
E
A
A
L
E
L
A
K
R
Y
G
K
K
L
D
L
E
K
I
--
S
--
K
D
E
K
V
Y
V
A
L
D
R
V
C
D
F
Y
R
E
S
L
L
K
-----
N
R
------
E
A
S
E
-----
Y
V
K
S
R
G
I
D
P
K
V
A
R
K
F
D
L
G
Y
A
P
S
S
E
-
A
--
L
V
K
V
L
K
E
N
D
L
L
E
---
A
Y
L
E
T
K
N
L
L
S
P
TKG
V
--------
Y
R
-----
D
L
F
L
R
R
V
V
I
P
I
K
D
P
R
G
R
V
I
G
F
G
G
R
R
I
V
E
D
K
S
P
K
Y
I
N
S
P
D
S
R
V
F
K
K
G
E
N
L
F
G
L
Y
E
A
K
E
Y
I
K
E
E
G
F
A
I
L
V
E
G
Y
F
D
L
L
R
L
F
S
E
G
I
R
N
V
V
A
P
L
G
T
A
L
T
Q
N
Q
A
N
L
L
S
K
F
T
K
K
V
Y
I
L
Y
D
G
D
D
A
G
R
K
A
M
K
S
A
I
P
L
L
L
---
S
A
G
V
E
V
Y
P
V
Y
L
P
E
G
Y
D
P
D
E
F
I
K
E
F
G
K
E
--
E
L
R
R
L
I
N
S
S
G
E
L
-
F
E
T
L
I
K
T
A
R
E
N
----
L
E
--------
E
K
T
R
E
F
R
Y
Y
L
G
F
I
S
D
G
V
R
R
F
A
L
A
S
E
F
H
T
K
Y
K
V
P
M
E
I
L
L
M
K
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
39
Fugue
83.90
32%
-92
- C4 -
1DD9
1
DNAG_ECOLI
A:
[20-333]
-------------------------------------------------------------------------------------------------------------
T
L
Y
Q
L
M
D
G
L
N
T
F
Y
Q
Q
---
S
L
Q
QPV
A
T
------
S
A
R
Q
-----
Y
L
E
K
R
G
L
S
H
E
V
I
A
R
F
A
I
G
F
A
P
P
G
WD
N
--
V
L
K
R
F
G
G
N
P
E
N
R
---
Q
S
L
I
D
A
G
M
L
V
T
---
N
R-------
S
Y
-----
D
R
F
R
E
R
V
M
F
P
I
R
D
K
R
G
R
V
I
G
F
G
G
R
V
L
G
N
D
T
-
P
K
Y
L
N
S
P
E
T
D
I
F
H
K
G
R
Q
L
Y
G
L
Y
E
A
Q
Q
D
N
A
E
P
N
R
L
L
V
V
E
G
Y
M
D
V
V
A
L
A
Q
Y
G
I
N
Y
A
V
A
S
L
G
S
T
-
T
A
D
H
I
Q
L
L
F
R
A
T
N
N
V
I
C
C
Y
D
G
D
R
A
G
R
D
A
A
W
R
A
L
E
T
A
L
P
Y
M
T
D
G
R
Q
L
R
F
M
F
L
P
D
G
E
D
P
D
T
L
V
R
K
E
--
G
K
E
A
F
E
A
R
M
E
Q
A
M
P
-----
L
S
A
F
L
F
N
S
L
M
P
Q
V
D
L
S
T
P
D
G
R
A
R
L
S
T
L
A
L
P
L
I
S
Q
V
P
G
E
T
L
R
I
Y
L
R
Q
E
L
G
N
K
L
G
I
L
D
D
S
Q
L
E
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
HHSearch
83.90
32%
-103
- C4 -
1DD9
1
DNAG_ECOLI
A:
[20-331]
-------------------------------------------------------------------------------------------------------------
T
L
Y
Q
L
M
D
G
L
N
T
F
Y
Q
Q
---
S
L
Q
QPV
A
T
------
S
A
R
Q
-----
Y
L
E
K
R
G
L
S
H
E
V
I
A
R
F
A
I
G
F
A
P
P
G
WD
N
--
V
L
K
R
F
G
G
N
P
E
N
R
---
Q
S
L
I
D
A
G
M
L
V
T
N--
R
--------
S
Y
-----
D
R
F
R
E
R
V
M
F
P
I
R
D
K
R
G
R
V
I
G
F
G
G
R
V
L
G
N
-
D
T
P
K
Y
L
N
S
P
E
T
D
I
F
H
K
G
R
Q
L
Y
G
L
Y
E
A
Q
Q
D
N
A
E
P
N
R
L
L
V
V
E
G
Y
M
D
V
V
A
L
A
Q
Y
G
I
N
Y
A
V
A
S
L
G
-
S
T
T
A
D
H
I
Q
L
L
F
R
A
T
N
N
V
I
C
C
Y
D
G
D
R
A
G
R
D
A
A
W
R
A
L
E
T
A
L
P
Y
M
T
D
G
R
Q
L
R
F
M
F
L
P
D
G
E
D
P
D
T
L
V
R
K
E
G
K
E
--
A
F
E
A
R
M
E
Q
A
M
P
L
-
S
A
F
L
F
N
S
L
M
P
Q
----
V
D
L
S
T
P
D
G
R
A
R
L
S
T
L
A
L
P
L
I
S
Q
V
P
G
E
T
L
R
I
Y
L
R
Q
E
L
G
N
K
L
G
I
L
D
D
S
Q
L
E
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
83.33
32%
-90
- C4 -
3B39
2
DNAG_ECOLI
A:
[3-318]
------------------------------------------------------------------------------------------------------
A
H
--
Q
R
Q
T
L
Y
Q
L
M
D
G
L
N
T
F
Y
Q
Q
---
S
-----
L
Q
------
Q
P
V
A
T
S
A
R
Q
Y
L
E
K
R
G
L
S
H
E
V
I
A
R
F
A
I
G
F
A
P
P
---
G
--
W
D
N
V
L
K
R
F
G
G
N
P
E
N
R
Q
S
L
I
D
A
G
M
L
V
T
---
N
DR------
S
Y
-----
D
R
F
R
E
R
V
M
F
P
I
R
D
K
R
G
R
V
I
G
F
G
G
R
V
L
G
N
D
T
-
P
K
Y
L
N
S
P
E
T
D
I
F
H
K
G
R
Q
L
Y
G
L
Y
E
A
Q
Q
D
N
A
E
P
N
R
L
L
V
V
E
G
Y
M
D
V
V
A
L
A
Q
Y
G
I
N
Y
A
V
A
S
L
G
T
S
T
T
A
D
H
I
Q
L
L
F
R
A
T
N
N
V
I
C
C
Y
D
G
D
R
A
G
R
D
A
A
W
C
A
L
E
T
A
L
P
Y
M
T
D
G
R
Q
L
R
F
M
F
L
P
D
G
E
D
P
D
T
L
V
R
--
K
E
G
K
E
A
F
E
A
R
M
E
Q
A
M
P
L
S
A
-----
F
L
F
N
S
L
M
P
Q
V
D
L
S
T
P
D
G
R
A
R
L
S
T
L
A
L
P
L
I
S
Q
V
P
G
E
T
L
R
I
Y
L
R
Q
E
L
G
N
K
L
G
I
L
D
D
S
Q
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_CBE
82.53
32%
-94
- C4 -
3B39
1
DNAG_ECOLI
B:
[3-311]
------------------------------------------------------------------------------------------------------
A
H
--
Q
R
Q
T
L
Y
Q
L
M
D
G
L
N
T
F
Y
Q
Q
---
S
-----
L
Q
------
Q
P
V
A
T
S
A
R
Q
Y
L
E
K
R
G
L
S
H
E
V
I
A
R
F
A
I
G
F
A
P
P
---
G
--
W
D
N
V
L
K
R
F
G
G
N
P
E
N
R
Q
S
L
I
D
A
G
M
L
V
T
---
N
DQG
R
----
S
Y
-----
D
R
F
R
E
R
V
M
F
P
I
R
D
K
R
G
R
V
I
G
F
G
G
R
V
L
G
N
D
T
-
P
K
Y
L
N
S
P
E
T
D
I
F
H
K
G
R
Q
L
Y
G
L
Y
E
A
Q
Q
D
N
A
E
P
N
R
L
L
V
V
E
G
Y
M
D
V
V
A
L
A
Q
Y
G
I
N
Y
A
V
A
S
L
G
T
S
T
T
A
D
H
I
Q
L
L
F
R
A
T
N
N
V
I
C
C
Y
D
G
D
R
A
G
R
D
A
A
W
C
A
L
E
T
A
L
P
Y
M
T
D
G
R
Q
L
R
F
M
F
L
P
D
G
E
D
P
D
T
L
V
R
--
K
E
G
K
E
A
F
E
A
R
M
E
Q
A
M
P
L
S
A
-----
F
L
F
N
S
L
M
P
Q
V
D
L
S
T
P
D
G
R
A
R
L
S
T
L
A
L
P
L
I
S
Q
V
P
G
E
T
L
R
I
Y
L
R
Q
E
L
G
N
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
81.40
37%
-97
- C4 -
2AU3
1
DNAG_AQUAE
A:
[7-336]
--------
I
D
E
L
R
R
E
I
D
I
V
D
V
I
S
E
Y
L
N
L
E
K
V
G
S
N
Y
R
T
N
C
P
F
H
P
D
D
T
P
S
F
Y
V
S
P
S
K
Q
I
F
K
C
F
G
C
G
V
G
G
D
A
I
K
F
V
S
L
Y
E
D
I
S
Y
F
E
A
A
L
E
L
A
K
R
Y
G
----
K
K
L
D
L
E
K
IS
K
D
E
K
V
Y
V
A
L
D
R
V
C
D
F
Y
R
E
S
L
L
K
-----
N
R
------
E
A
S
E
-----
Y
V
K
S
R
G
I
D
P
K
V
A
R
K
F
D
L
G
Y
A
P
S
S
-------
E
A
L
V
K
V
-
L
K
E
---
N
D
L
L
E
A
Y
L
E
T
K
---
N
LLSPTKG
V
Y
R
-----
D
L
F
L
R
R
V
V
I
P
I
K
D
P
R
G
R
V
I
G
F
G
G
R
R
I
V
E
D
K
S
P
K
Y
I
N
S
P
D
S
R
V
F
K
K
G
E
N
L
F
G
L
Y
E
A
K
E
Y
I
K
E
E
G
F
A
I
L
V
E
G
Y
F
D
L
L
R
L
F
S
E
G
I
R
N
V
V
A
P
L
G
T
A
L
T
Q
N
Q
A
N
L
L
S
K
F
T
K
K
V
Y
I
L
Y
D
G
D
D
A
G
R
K
A
M
K
S
A
I
P
L
---
L
L
S
A
G
V
E
V
Y
P
V
Y
L
P
E
G
Y
D
P
D
E
F
I
K
E
F
G
K
E
E
L
R
R
L
I
N
S
S
G
E
L
F
E
T
L
I
K
T
A
R
E
N
L
E
E
K
T
R
E
F
R
Y
Y
L
G
F
I
S
D
G
V
R
R
F
A
L
A
S
E
F
H
T
K
Y
K
V
P
M
E
I
L
L
M
K
I
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
80.72
34%
-92
- C4 -
1DDE
4
DNAG_ECOLI
A:
[47-330]
------------------------------------------------------------------------------------------------------------------------------------------------------
Y
L
E
K
R
G
L
S
H
E
V
I
A
R
F
A
I
G
F
A
P
P
---
G
--
W
D
N
V
L
K
R
F
G
G
N
P
E
N
R
Q
S
L
I
D
A
G
M
L
V
T
---
N
R-------
S
Y
-----
D
R
F
R
E
R
V
M
F
P
I
R
D
K
R
G
R
V
I
G
F
G
G
R
V
L
G
N
D
T
-
P
K
Y
L
N
S
P
E
T
D
I
F
H
K
G
R
Q
L
Y
G
L
Y
E
A
Q
Q
D
N
A
E
P
N
R
L
L
V
V
E
G
Y
M
D
V
V
A
L
A
Q
Y
G
I
N
Y
A
V
A
S
L
G
T
S
T
T
A
D
H
I
Q
L
L
F
R
A
T
N
N
V
I
C
C
Y
D
G
D
R
A
G
R
D
A
A
W
R
A
L
E
T
A
L
P
Y
M
T
D
G
R
Q
L
R
F
M
F
L
P
D
G
E
D
P
D
T
L
V
R
--
K
E
G
K
E
A
F
E
A
R
M
E
Q
A
M
P
L
S
A
-----
F
L
F
N
S
L
M
P
Q
V
D
L
S
T
P
D
G
R
A
R
L
S
T
L
A
L
P
L
I
S
Q
V
P
G
E
T
L
R
I
Y
L
R
Q
E
L
G
N
K
L
G
I
L
D
D
S
Q
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
80.56
34%
-90
- C4 -
1DD9
1
DNAG_ECOLI
A:
[47-330]
------------------------------------------------------------------------------------------------------------------------------------------------------
Y
L
E
K
R
G
L
S
H
E
V
I
A
R
F
A
I
G
F
A
P
P
---
G
--
W
D
N
V
L
K
R
F
G
G
N
P
E
N
R
Q
S
L
I
D
A
G
M
L
V
T
---
N
R-------
S
Y
-----
D
R
F
R
E
R
V
M
F
P
I
R
D
K
R
G
R
V
I
G
F
G
G
R
V
L
G
N
D
T
-
P
K
Y
L
N
S
P
E
T
D
I
F
H
K
G
R
Q
L
Y
G
L
Y
E
A
Q
Q
D
N
A
E
P
N
R
L
L
V
V
E
G
Y
M
D
V
V
A
L
A
Q
Y
G
I
N
Y
A
V
A
S
L
G
-
S
T
T
A
D
H
I
Q
L
L
F
R
A
T
N
N
V
I
C
C
Y
D
G
D
R
A
G
R
D
A
A
W
R
A
L
E
T
A
L
P
Y
M
T
D
G
R
Q
L
R
F
M
F
L
P
D
G
E
D
P
D
T
L
V
R
--
K
E
G
K
E
A
F
E
A
R
M
E
Q
A
M
P
L
S
A
-----
F
L
F
N
S
L
M
P
Q
V
D
L
S
T
P
D
G
R
A
R
L
S
T
L
A
L
P
L
I
S
Q
V
P
G
E
T
L
R
I
Y
L
R
Q
E
L
G
N
K
L
G
I
L
D
D
S
Q
L
E
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
40
Fugue
75.85
24%
-93
- C4 -
4EDK
7
DNAG_STAAU
A:
[1-321]
-----------------------------------------------------------------------------------------------------
S
N
A
--
D
D
L
Q
M
I
E
M
H
E
L
I
Q
E
F
Y
Y
Y
---
A
-----
L
T
KTVEG
E
Q
A
L
T
-----
Y
L
Q
E
R
G
F
T
D
A
L
I
K
E
R
G
I
G
F
A
P
D
S
--
S
H
F
C
H
D
F
L
Q
K
K
G
Y
D
I
---
E
L
A
Y
E
A
G
L
L
S
R
---
N
--------
E
E
NF
S
Y
Y
D
R
F
R
N
R
I
M
F
P
L
K
N
A
Q
G
R
I
V
G
Y
S
G
R
T
Y
T
G
Q
E
-
P
K
Y
L
N
S
P
E
T
P
I
F
Q
K
R
K
L
L
Y
N
L
D
K
A
R
K
S
I
R
K
L
D
E
I
V
L
L
E
G
F
M
D
V
I
K
S
D
T
A
G
L
K
N
V
V
A
T
M
G
T
Q
L
S
D
E
H
I
T
F
I
R
K
L
T
S
N
I
T
L
M
F
D
G
D
F
A
G
S
E
A
T
L
K
T
G
Q
H
L
L
Q
---
Q
G
L
N
V
F
V
I
Q
L
P
S
G
M
D
P
D
E
Y
I
G
K
Y
--
G
N
D
A
F
T
T
F
V
K
N
D
K
K
S
F
A
H
Y
K
V
S
I
L
K
D
E
I
A
H
N
-----
D
L
S
Y
E
R
Y
L
K
E
L
S
H
D
I
S
L
M
K
S
S
I
L
Q
Q
K
A
I
N
D
V
A
P
F
F
N
V
S
P
E
Q
L
A
N
E
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
66.75
33%
-104
- C4 -
4EDR
6
DNAG_STAAU
A:
[33-237]
-----------------------------------------------------------------------------------------------------------------------------------------------
L
T
-----
Y
L
Q
E
R
G
F
T
D
A
L
I
K
E
R
G
I
G
F
A
P
D
S
--
S
H
F
C
H
D
F
L
Q
K
K
G
Y
D
I
---
E
L
A
Y
E
A
G
L
L
S
R
---
N
--------
E
E
NF
S
Y
Y
D
R
F
R
N
R
I
M
F
P
L
K
N
A
Q
G
R
I
V
G
Y
S
G
R
T
Y
T
G
-
Q
E
P
K
Y
L
N
S
P
E
T
P
I
F
Q
K
R
K
L
L
Y
N
L
D
K
A
R
K
S
I
R
K
L
D
E
I
V
L
L
E
G
F
M
D
V
I
K
S
D
T
A
G
L
K
N
V
V
A
T
M
G
T
Q
L
S
D
E
H
I
T
F
I
R
K
L
T
S
N
I
T
L
M
F
D
G
D
F
A
G
S
E
A
T
L
K
T
G
Q
---
H
L
L
Q
Q
G
L
N
V
F
V
I
Q
L
P
S
G
M
D
P
D
E
Y
I
G
K
Y
G
N
D
A
F
T
T
F
V
K
N
D
K
K
S
F
A
H
Y
K
V
S
I
L
K
D
E
I
A
H
N
D
L
S
Y
E
R
Y
L
K
E
L
S
H
D
I
S
L
M
K
S
S
I
L
Q
Q
K
A
I
N
D
V
A
P
F
F
N
V
S
P
E
Q
L
A
N
E
I
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
66.25
33%
-102
- C4 -
4EDT
3
DNAG_STAAU
A:
[33-237]
-----------------------------------------------------------------------------------------------------------------------------------------------
L
T
-----
Y
L
Q
E
R
G
F
T
D
A
L
I
K
E
R
G
I
G
F
A
P
D
S
--
S
H
F
C
H
D
F
L
Q
K
K
G
Y
D
I
---
E
L
A
Y
E
A
G
L
L
S
R
---
N
--------
E
E
NF
S
Y
Y
D
R
F
R
N
R
I
M
F
P
L
K
N
A
Q
G
R
I
V
G
Y
S
G
R
T
Y
T
G
-
Q
E
P
K
Y
L
N
S
P
E
T
P
I
F
Q
K
R
K
L
L
Y
N
L
D
K
A
R
K
S
I
R
K
L
D
E
I
V
L
L
E
G
F
M
D
V
I
K
S
D
T
A
G
L
K
N
V
V
A
T
M
G
T
Q
L
S
D
E
H
I
T
F
I
R
K
L
T
S
N
I
T
L
M
F
D
G
D
F
A
G
S
E
A
T
L
K
T
G
Q
---
H
L
L
Q
Q
G
L
N
V
F
V
I
Q
L
P
S
G
M
D
P
D
E
Y
I
G
K
Y
G
N
D
A
F
T
T
F
V
K
N
D
K
K
S
F
A
H
Y
K
V
S
I
L
K
D
E
I
A
H
N
D
L
S
Y
E
R
Y
L
K
E
L
S
H
D
I
S
L
M
K
S
S
I
L
Q
Q
K
A
I
N
D
V
A
P
F
F
N
V
S
P
E
Q
L
A
N
E
I
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
66.24
33%
-104
- C4 -
4EDK
6
DNAG_STAAU
A:
[33-237]
-----------------------------------------------------------------------------------------------------------------------------------------------
L
T
-----
Y
L
Q
E
R
G
F
T
D
A
L
I
K
E
R
G
I
G
F
A
P
D
S
--
S
H
F
C
H
D
F
L
Q
K
K
G
Y
D
I
---
E
L
A
Y
E
A
G
L
L
S
R
---
N
--------
E
E
NF
S
Y
Y
D
R
F
R
N
R
I
M
F
P
L
K
N
A
Q
G
R
I
V
G
Y
S
G
R
T
Y
T
G
-
Q
E
P
K
Y
L
N
S
P
E
T
P
I
F
Q
K
R
K
L
L
Y
N
L
D
K
A
R
K
S
I
R
K
L
D
E
I
V
L
L
E
G
F
M
D
V
I
K
S
D
T
A
G
L
K
N
V
V
A
T
M
G
T
Q
L
S
D
E
H
I
T
F
I
R
K
L
T
S
N
I
T
L
M
F
D
G
D
F
A
G
S
E
A
T
L
K
T
G
Q
---
H
L
L
Q
Q
G
L
N
V
F
V
I
Q
L
P
S
G
M
D
P
D
E
Y
I
G
K
Y
G
N
D
A
F
T
T
F
V
K
N
D
K
K
S
F
A
H
Y
K
V
S
I
L
K
D
E
I
A
H
N
D
L
S
Y
E
R
Y
L
K
E
L
S
H
D
I
S
L
M
K
S
S
I
L
Q
Q
K
A
I
N
D
V
A
P
F
F
N
V
S
P
E
Q
L
A
N
E
I
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
66.12
33%
-101
- C4 -
4EE1
4
DNAG_STAAU
A:
[33-237]
-----------------------------------------------------------------------------------------------------------------------------------------------
L
T
-----
Y
L
Q
E
R
G
F
T
D
A
L
I
K
E
R
G
I
G
F
A
P
D
S
--
S
H
F
C
H
D
F
L
Q
K
K
G
Y
D
I
---
E
L
A
Y
E
A
G
L
L
S
R
---
N
--------
E
E
NF
S
Y
Y
D
R
F
R
N
R
I
M
F
P
L
K
N
A
Q
G
R
I
V
G
Y
S
G
R
T
Y
T
G
-
Q
E
P
K
Y
L
N
S
P
E
T
P
I
F
Q
K
R
K
L
L
Y
N
L
D
K
A
R
K
S
I
R
K
L
D
E
I
V
L
L
E
G
F
M
D
V
I
K
S
D
T
A
G
L
K
N
V
V
A
T
M
G
T
Q
L
S
D
E
H
I
T
F
I
R
K
L
T
S
N
I
T
L
M
F
D
G
D
F
A
G
S
E
A
T
L
K
T
G
Q
---
H
L
L
Q
Q
G
L
N
V
F
V
I
Q
L
P
S
G
M
D
P
D
E
Y
I
G
K
Y
G
N
D
A
F
T
T
F
V
K
N
D
K
K
S
F
A
H
Y
K
V
S
I
L
K
D
E
I
A
H
N
D
L
S
Y
E
R
Y
L
K
E
L
S
H
D
I
S
L
M
K
S
S
I
L
Q
Q
K
A
I
N
D
V
A
P
F
F
N
V
S
P
E
Q
L
A
N
E
I
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
65.69
33%
-103
- C4 -
4EDG
5
DNAG_STAAU
A:
[33-237]
-----------------------------------------------------------------------------------------------------------------------------------------------
L
T
-----
Y
L
Q
E
R
G
F
T
D
A
L
I
K
E
R
G
I
G
F
A
P
D
S
--
S
H
F
C
H
D
F
L
Q
K
K
G
Y
D
I
---
E
L
A
Y
E
A
G
L
L
S
R
---
N
--------
E
E
NF
S
Y
Y
D
R
F
R
N
R
I
M
F
P
L
K
N
A
Q
G
R
I
V
G
Y
S
G
R
T
Y
T
G
-
Q
E
P
K
Y
L
N
S
P
E
T
P
I
F
Q
K
R
K
L
L
Y
N
L
D
K
A
R
K
S
I
R
K
L
D
E
I
V
L
L
E
G
F
M
D
V
I
K
S
D
T
A
G
L
K
N
V
V
A
T
M
G
T
Q
L
S
D
E
H
I
T
F
I
R
K
L
T
S
N
I
T
L
M
F
D
G
D
F
A
G
S
E
A
T
L
K
T
G
Q
---
H
L
L
Q
Q
G
L
N
V
F
V
I
Q
L
P
S
G
M
D
P
D
E
Y
I
G
K
Y
G
N
D
A
F
T
T
F
V
K
N
D
K
K
S
F
A
H
Y
K
V
S
I
L
K
D
E
I
A
H
N
D
L
S
Y
E
R
Y
L
K
E
L
S
H
D
I
S
L
M
K
S
S
I
L
Q
Q
K
A
I
N
D
V
A
P
F
F
N
V
S
P
E
Q
L
A
N
E
I
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
65.25
33%
-105
- C4 -
4EDV
4
DNAG_STAAU
A:
[33-237]
-----------------------------------------------------------------------------------------------------------------------------------------------
L
T
-----
Y
L
Q
E
R
G
F
T
D
A
L
I
K
E
R
G
I
G
F
A
P
D
S
--
S
H
F
C
H
D
F
L
Q
K
K
G
Y
D
I
---
E
L
A
Y
E
A
G
L
L
S
R
---
N
--------
E
E
NF
S
Y
Y
D
R
F
R
N
R
I
M
F
P
L
K
N
A
Q
G
R
I
V
G
Y
S
G
R
T
Y
T
G
-
Q
E
P
K
Y
L
N
S
P
E
T
P
I
F
Q
K
R
K
L
L
Y
N
L
D
K
A
R
K
S
I
R
K
L
D
E
I
V
L
L
E
G
F
M
D
V
I
K
S
D
T
A
G
L
K
N
V
V
A
T
M
G
T
Q
L
S
D
E
H
I
T
F
I
R
K
L
T
S
N
I
T
L
M
F
D
G
D
F
A
G
S
E
A
T
L
K
T
G
Q
---
H
L
L
Q
Q
G
L
N
V
F
V
I
Q
L
P
S
G
M
D
P
D
E
Y
I
G
K
Y
G
N
D
A
F
T
T
F
V
K
N
D
K
K
S
F
A
H
Y
K
V
S
I
L
K
D
E
I
A
H
N
D
L
S
Y
E
R
Y
L
K
E
L
S
H
D
I
S
L
M
K
S
S
I
L
Q
Q
K
A
I
N
D
V
A
P
F
F
N
V
S
P
E
Q
L
A
N
E
I
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
HHSearch
55.46
45%
-106
- C5 -
1D0Q
1
DNAG_GEOSE
A:
[8-99]
------
E
T
I
E
A
I
R
R
G
V
D
I
V
D
V
I
G
E
Y
V
Q
L
K
R
Q
G
R
N
Y
F
G
L
C
P
F
H
G
E
K
T
P
S
F
S
V
S
P
E
K
Q
I
F
H
C
F
G
C
G
A
G
G
N
A
F
T
F
L
M
D
I
E
G
I
P
F
V
E
A
A
K
R
L
A
A
K
A
G
V
D
L
S
V
Y
E
L
D
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
55.26
46%
-106
- C5 -
1D0Q
1
DNAG_GEOSE
A:
[10-97]
--------
I
E
A
I
R
R
G
V
D
I
V
D
V
I
G
E
Y
V
Q
L
K
R
Q
G
R
N
Y
F
G
L
C
P
F
H
G
E
K
T
P
S
F
S
V
S
P
E
K
Q
I
F
H
C
F
G
C
G
A
G
G
N
A
F
T
F
L
M
D
I
E
G
I
P
F
V
E
A
A
K
R
L
A
A
K
A
G
V
D
L
S
V
Y
E
L
D
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
PsiBlast_CBE
54.41
46%
-100
- C5 -
1D0Q
1
DNAG_GEOSE
B:
[10-97]
--------
I
E
A
I
R
R
G
V
D
I
V
D
V
I
G
E
Y
V
Q
L
K
R
Q
G
R
N
Y
F
G
L
C
P
F
H
G
E
K
T
P
S
F
S
V
S
P
E
K
Q
I
F
H
C
F
G
C
G
A
G
G
N
A
F
T
F
L
M
D
I
E
G
I
P
F
V
E
A
A
K
R
L
A
A
K
A
G
V
D
L
S
V
Y
E
L
D
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
41
Fugue
54.02
42%
-94
- C5 -
1D0Q
1
DNAG_GEOSE
A:
[2-103]
GHRIP
E
E
T
I
E
A
I
R
R
G
V
D
I
V
D
V
I
G
E
Y
V
Q
L
K
R
Q
G
R
N
Y
F
G
L
C
P
F
H
G
E
K
T
P
S
F
S
V
S
P
E
K
Q
I
F
H
C
F
G
C
G
A
G
G
N
A
F
T
F
L
M
D
I
E
G
I
P
F
V
E
A
A
K
R
L
A
A
K
A
G
V
D
L
S
V
Y
E
L
D
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
52.98
42%
-28
- C4 -
1EQN
-
DNAG_ECOLI
A:
[142-346]
------------------------------------------------------------------------------------------------------------------------------------------------------
Y
L
E
K
R
G
L
S
H
E
V
I
A
R
F
A
I
G
F
A
P
P
---
G
--
W
D
N
V
L
K
R
F
G
G
N
P
E
N
R
Q
S
L
I
D
A
G
M
L
V
T
---
N
DQG
R
----
S
Y
-----
D
R
F
R
E
R
V
M
F
P
I
R
D
K
R
G
R
V
I
G
F
G
G
R
V
L
G
N
D
T
-
P
K
Y
L
N
S
P
E
T
D
I
F
H
K
G
R
Q
L
Y
G
L
Y
E
A
Q
Q
D
N
A
E
P
N
R
L
L
V
V
E
G
Y
M
D
V
V
A
L
A
Q
Y
G
I
N
Y
A
V
A
S
L
G
T
S
T
T
A
D
H
I
Q
L
L
F
R
A
T
N
N
V
I
C
C
Y
D
G
D
R
A
G
R
D
A
A
W
R
A
L
E
T
A
L
P
Y
M
T
D
G
R
Q
L
R
F
M
F
L
P
D
G
E
D
P
D
T
L
V
R
K
E
G
K
E
A
F
E
A
R
M
E
Q
A
M
P
L
S
A
F
L
F
N
S
L
M
P
Q
V
D
L
S
T
P
D
G
R
A
R
L
S
T
L
A
L
P
L
I
S
Q
V
P
G
E
T
L
R
I
Y
L
R
Q
E
L
G
N
K
L
G
I
L
D
D
S
Q
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------