@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Wbm0255: (2015-11-29 )
MLDKMYEECGVFGISCNKDSAFDSILGLHALQHRGQESFGVVTSNNDKLHSYHFQGQVSSVLDNIDEIKKSLPGNYAIGHVRYSTSGNKSGVQPILGKSNKFGDFAIAHNGNLINISPIREQLIKQGRVFQSDIDTEVVARLVEANTKNSFLGSFIYALKQIQGAYSFVAINREVVVGVRDSAGIRPLVLGKLNSSYVLASETCALDIVNAEFIREIEPGELVTIDQNGNLASAFPLSQQKSSFCIFEYIYFSRPDSIIEDRSIYDIRKEIGRTLAEESPPKNNVDMVVPIPDSGIPAAIGYTKYSGLPIELGIIRNHYIGRTFIQPTAEVRKVRIKLKFNANKDILKGKNIILIDDSIVRGSTLKSIIVMLKDAGVKEIHLKISSPPIKYSCFYGIDTPECKDLIAASKSVREIEAIIGVNSLTFLSIDGLYQAVNGEKRNNTAPQYCDACFTGDYPIGK
Atome Classification :
(20 SA)
.........10....----....20........30........40-..-..-.-...50........60........70........80......-.-.90--........100.......110.......120....-...-130.......140....--.---------..---------150.......160.......170--..---......180.......190..-----..--...200.......210.......220.......230...---....240.......250.......260.......270.......280---.---......290.......300.......310.......320.....--..330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460----------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
L
D
K
M
Y
E
E
CG
V
F
G
I
S----CNKD
S
A
F
D
S
I
L
G
L
H
A
L
Q
H
RGQE
S
F
G
V
-
V
T-SN-N-D
K
L
H
S
Y
H
FQG
Q
V
S
S
V
L
D
N
I
D
E
I
K
K
SLPGN
Y
A
I
G
H
V
R
Y
STSG-N-KSG--VQPILGKSNKFG
D
F
A
I
AHNG
N
L
I
N
I
S
P
I
R
E
Q
L
I
KQ-GRV-FQSDI
D
T
E
V
V
A
R
L
V
EAN--T---------K
N
---------
S
F
L
G
S
F
I
Y
A
L
K
Q
I
QGA
Y
S
F
V
A
-I--N
R
---
E
V
V
V
G
VRDSAGI
R
P
L
V
L
GKLN-----S
S
--
Y
V
L
ASE
T
C
A
L
D
IV
N
A
E
F
I
REIEPG
E
L
V
T
IDQNGNLASAF---PLSQQKS
S
F
C
I
F
E
Y
I
YFSR
P
D
S
I
IEDR
S
I
Y
D
I
R
K
E
I
G
R
T
L
A
EESPPK---N---NV
D
M
V
V
PIPDSGIPAAIGYTKYSG
L
P
I
E
L
G
I
I
RNHYIG
R
T
FIQP--TA
E
V
R
K
V
R
I
K
L
K
FNANKDILKGK
N
I
I
L
IDDSIVR
G
S
T
L
K
S
I
I
V
M
LKDAG
V
K
E
I
H
L
K
ISSPP
I
K
Y
S
C
F
YGID
T
P
E
C
K
D
L
I
A
A
S
K
S
V
R
E
I
E
A
I
IGVN
S
L
T
F
L
S
I
D
G
L
Y
Q
AVNGEKRNNTA
P
Q
Y
C
D
A
CFTGDYPIGK-----------
49
Fugue
93.45
44%
-112
- C3 -
1AO0
5
PUR1_BACSU
A:
[1-459]
--------
C
G
V
F
G
I
W
----
G
H
E
E
A
P
Q
I
T
Y
Y
G
L
H
S
L
Q
H
R
G
Q
E
G
A
G
I
-
V
A
T
D
G
---
E
K
L
T
A
H
K
G
Q
G
L
I
T
E
V
F
Q
N
G
E
--
L
S
K
V
K
G
K
G
A
I
G
H
V
R
Y
A
T
G
----
Y
E
N
--
V
Q
P
L
L
F
R
S
Q
N
N
G
S
L
A
L
A
H
N
G
N
L
V
N
A
T
Q
L
K
Q
Q
L
E
N
Q
-
G
S
I
-
F
Q
T
S
S
D
T
E
V
L
A
H
L
I
K
R
S
--
G
HF------------------
T
L
K
D
Q
I
K
N
S
L
S
M
L
K
G
A
Y
A
F
L
I
-
M
T
E
T
-----
E
M
I
V
A
L
D
P
N
G
L
R
P
L
S
I
G
M
M
G
-------D
A
Y
V
V
A
S
E
T
C
A
F
D
V
V
G
A
T
Y
L
R
E
V
E
P
G
E
M
L
I
I
N
D
E
-
G
M
K
S
E
R
FSM---
N
I
N
R
S
I
C
S
M
E
Y
I
Y
F
S
R
P
D
S
N
I
D
G
I
N
V
H
S
A
R
K
N
L
G
K
M
L
A
Q
E
S
A
------
V
--
E
A
D
V
V
T
G
V
P
D
S
S
I
S
A
A
I
G
Y
A
E
A
T
G
I
P
Y
E
L
G
L
I
K
N
R
Y
V
G
R
T
F
I
--QP
S
Q
A
L
R
E
Q
G
V
R
M
K
L
S
A
V
R
G
V
V
E
G
K
R
V
V
M
V
D
D
S
I
V
R
G
T
T
S
R
R
I
V
T
M
L
R
E
A
G
A
T
E
V
H
V
K
I
S
S
P
P
I
A
H
P
C
F
Y
G
I
D
T
S
T
H
E
E
L
I
A
S
S
H
S
V
E
E
I
R
Q
E
I
G
A
D
T
L
S
F
L
S
V
E
G
L
L
K
G
I
G
R
K
Y
D
D
S
N
-
C
G
Q
C
L
A
C
F
T
G
K
Y
P
T
E
-
I
Y
QDTVLPHVK
27
HHSearch
88.97
36%
-100
- C3 -
1ECF
3
PUR1_ECOLI
A:
[1-468]
--------
C
G
I
V
G
I
A
----
G
V
M
P
V
N
Q
S
I
Y
D
A
L
T
V
L
Q
H
R
G
Q
D
A
A
G
I
-
I
T
-
I
D
-
A
N
N
C
F
R
L
R
K
A
N
G
L
V
S
D
V
F
E
--
A
R
H
M
Q
R
L
Q
G
N
M
G
I
G
H
V
R
Y
P
T
A
G
S
S
S
A
S
E
--
A
Q
P
F
Y
V
N
S
--
P
Y
G
I
T
L
A
H
N
G
N
L
T
N
A
H
E
L
R
K
K
L
F
E
E
K
R
R
H
-
I
N
T
T
S
D
S
E
I
L
L
N
I
F
A
S
E
--
L
D
NFRHYPLE
A
D
---------
N
I
F
A
A
I
A
A
T
N
R
L
I
R
G
A
Y
A
C
V
A
-
M
--
I
I
G--
H
G
M
V
A
F
R
D
P
N
G
I
R
P
L
V
L
G
K
R
D
IDEN
R
T
E
--
Y
M
V
A
S
E
S
V
A
L
D
T
L
G
F
D
F
L
R
D
V
A
P
G
E
A
I
Y
I
T
E
E
G
Q
L
F
T
R
Q
---
C
A
D
N
P
V
S
N
P
C
L
F
E
Y
V
Y
F
A
R
P
D
S
F
I
D
K
I
S
V
Y
S
A
R
V
N
M
G
T
K
L
G
E
K
I
A
R
E
WED
L
---
D
I
D
V
V
I
P
I
P
E
T
S
C
D
I
A
L
E
I
A
R
I
L
G
K
P
Y
R
Q
G
F
V
K
N
R
Y
V
G
R
T
F
I
M
P
--
G
Q
Q
L
R
R
K
S
V
R
R
K
L
N
A
N
R
A
E
F
R
D
K
N
V
L
L
V
D
D
S
I
V
R
G
T
T
S
E
Q
I
I
E
M
A
R
E
A
G
A
K
K
V
Y
L
A
S
A
A
P
E
I
R
F
P
N
V
Y
G
I
D
M
P
S
A
T
E
L
I
A
H
G
R
E
V
D
E
I
R
Q
I
I
G
A
D
G
L
I
F
Q
D
L
N
D
L
I
D
A
V
R
A
E
--
N
P
D
I
Q
Q
F
E
C
S
V
F
N
G
V
Y
V
T
K
D
-----------
25
PsiBlast_CBE
87.96
35%
-101
- C3 -
1ECB
4
PUR1_ECOLI
C:
[1-465]
--------
C
G
I
V
G
I
A
GVMP
V
N
Q
-
S
I
Y
D
A
---
L
T
V
L
Q
H
R
G
Q
D
A
A
G
I
-
I
T
-
I
D
A
N
-
N
C
F
R
L
R
K
A
N
G
L
V
S
D
V
F
E
A
--
R
H
M
Q
R
L
Q
G
N
M
G
I
G
H
V
R
Y
P
T
A
G
-
S
-
S
S
A
SE
A
Q
P
F
Y
V
N
S
-
P
Y
G
-
I
T
L
A
H
N
G
N
L
T
N
A
H
E
L
R
K
K
L
F
E
E
-
K
R
R
H
I
N
T
T
S
D
S
E
I
L
L
N
I
F
A
S
E
--
L
---------
D
N
FRHYPLE
A
D
N
I
F
A
A
I
A
A
T
N
R
L
I
R
G
A
Y
A
C
V
A
M
I
--
I
G
---
H
G
M
V
A
F
R
D
P
N
G
I
R
P
L
V
L
G
K
R
D
IDEN
R
T
E
--
Y
M
V
A
S
E
S
V
A
L
D
T
L
G
F
D
F
L
R
D
V
A
P
G
E
A
I
Y
I
T
E
E
G
Q
L
F
T
R
Q
---
C
A
D
N
P
V
S
N
P
C
L
F
E
Y
V
Y
F
A
R
P
D
S
F
I
D
K
I
S
V
Y
S
A
R
V
N
M
G
T
K
L
G
E
K
I
A
R
E
---
W
EDL
D
I
D
V
V
I
P
I
P
E
T
S
C
D
I
A
L
E
I
A
R
I
L
G
K
P
Y
R
Q
G
F
V
K
N
R
Y
V
G
R
T
F
I
M
P
--
G
Q
Q
L
R
R
K
S
V
R
R
K
L
N
A
N
R
A
E
F
R
D
K
N
V
L
L
V
D
D
S
I
V
R
G
T
T
S
E
Q
I
I
E
M
A
R
E
A
G
A
K
K
V
Y
L
A
S
A
A
P
E
I
R
F
P
N
V
Y
G
I
D
M
P
S
A
T
E
L
I
A
H
G
R
E
V
D
E
I
R
Q
I
I
G
A
D
G
L
I
F
Q
D
L
N
D
L
I
D
A
V
R
A
E
--
N
P
D
I
Q
Q
F
E
C
S
V
F
N
G
V
Y
V
T
K
D
-----------
23
PsiBlast_CBE
86.98
35%
-98
- C3 -
1ECC
6
PUR1_ECOLI
B:
[1-465]
--------
C
G
I
V
G
I
A
GVMP
V
N
Q
-
S
I
Y
D
A
---
L
T
V
L
Q
H
R
G
Q
D
A
A
G
I
-
I
T
-
I
D
A
N
-
N
C
F
R
L
R
K
A
N
G
L
V
S
D
V
F
E
A
--
R
H
M
Q
R
L
Q
G
N
M
G
I
G
H
V
R
Y
P
T
A
G
-
S
-
S
S
A
SE
A
Q
P
F
Y
V
N
S
-
P
Y
G
-
I
T
L
A
H
N
G
N
L
T
N
A
H
E
L
R
K
K
L
F
E
E
-
K
R
R
H
I
N
T
T
S
D
S
E
I
L
L
N
I
F
A
S
E
--
L
---------
D
N
FRHYPLEAD
N
I
F
A
A
I
A
A
T
N
R
L
I
R
G
A
Y
A
C
V
A
M
I
--
I
G
---
H
G
M
V
A
F
R
D
P
N
G
I
R
P
L
V
L
G
K
R
D
IDENR
T
E
--
Y
M
V
A
S
E
S
V
A
L
D
T
L
G
F
D
F
L
R
D
V
A
P
G
E
A
I
Y
I
T
E
E
G
Q
L
F
T
R
Q
---
C
A
D
N
P
V
S
N
P
C
L
F
E
Y
V
Y
F
A
R
P
D
S
F
I
D
K
I
S
V
Y
S
A
R
V
N
M
G
T
K
L
G
E
K
I
A
R
E
---
W
EDL
D
I
D
V
V
I
P
I
P
E
T
S
C
D
I
A
L
E
I
A
R
I
L
G
K
P
Y
R
Q
G
F
V
K
N
R
Y
V
G
R
T
F
I
M
P
--
G
Q
Q
L
R
R
K
S
V
R
R
K
L
N
A
N
R
A
E
F
R
D
K
N
V
L
L
V
D
D
S
I
V
R
G
T
T
S
E
Q
I
I
E
M
A
R
E
A
G
A
K
K
V
Y
L
A
S
A
A
P
E
I
R
F
P
N
V
Y
G
I
D
M
P
S
A
T
E
L
I
A
H
G
R
E
V
D
E
I
R
Q
I
I
G
A
D
G
L
I
F
Q
D
L
N
D
L
I
D
A
V
R
A
E
--
N
P
D
I
Q
Q
F
E
C
S
V
F
N
G
V
Y
V
T
K
D
-----------
4
PsiBlast_PDB
86.97
35%
-97
- C3 -
1ECC
5
PUR1_ECOLI
A:
[1-465]
--------
C
G
I
V
G
I
A
GVMP
V
N
Q
-
S
I
Y
D
A
---
L
T
V
L
Q
H
R
G
Q
D
A
A
G
I
-
I
T
-
I
D
A
N
-
N
C
F
R
L
R
K
A
N
G
L
V
S
D
V
F
E
A
--
R
H
M
Q
R
L
Q
G
N
M
G
I
G
H
V
R
Y
P
T
A
G
-
S
-
S
S
A
SE
A
Q
P
F
Y
V
N
S
-
P
Y
G
-
I
T
L
A
H
N
G
N
L
T
N
A
H
E
L
R
K
K
L
F
E
E
-
K
R
R
H
I
N
T
T
S
D
S
E
I
L
L
N
I
F
A
S
E
--
L
---------
D
N
FRHYPLE
A
D
N
I
F
A
A
I
A
A
T
N
R
L
I
R
G
A
Y
A
C
V
A
M
I
--
I
G
---
H
G
M
V
A
F
R
D
P
N
G
I
R
P
L
V
L
G
K
R
D
IDE
N
R
T
E
--
Y
M
V
A
S
E
S
V
A
L
D
T
L
G
F
D
F
L
R
D
V
A
P
G
E
A
I
Y
I
T
E
E
G
Q
L
F
T
R
Q
---
C
A
D
N
P
V
S
N
P
C
L
F
E
Y
V
Y
F
A
R
P
D
S
F
I
D
K
I
S
V
Y
S
A
R
V
N
M
G
T
K
L
G
E
K
I
A
R
E
---
W
EDL
D
I
D
V
V
I
P
I
P
E
T
S
C
D
I
A
L
E
I
A
R
I
L
G
K
P
Y
R
Q
G
F
V
K
N
R
Y
V
G
R
T
F
I
M
P
--
G
Q
Q
L
R
R
K
S
V
R
R
K
L
N
A
N
R
A
E
F
R
D
K
N
V
L
L
V
D
D
S
I
V
R
G
T
T
S
E
Q
I
I
E
M
A
R
E
A
G
A
K
K
V
Y
L
A
S
A
A
P
E
I
R
F
P
N
V
Y
G
I
D
M
P
S
A
T
E
L
I
A
H
G
R
E
V
D
E
I
R
Q
I
I
G
A
D
G
L
I
F
Q
D
L
N
D
L
I
D
A
V
R
A
E
--
N
P
D
I
Q
Q
F
E
C
S
V
F
N
G
V
Y
V
T
K
D
-----------
1
PsiBlast_PDB
86.89
35%
-101
* C3 *
1ECF
3
PUR1_ECOLI
A:
[1-465]
--------
C
G
I
V
G
I
A
GVMP
V
N
Q
-
S
I
Y
D
A
---
L
T
V
L
Q
H
R
G
Q
D
A
A
G
I
-
I
T
-
I
D
A
N
-
N
C
F
R
L
R
K
A
N
G
L
V
S
D
V
F
E
A
--
R
H
M
Q
R
L
Q
G
N
M
G
I
G
H
V
R
Y
P
T
A
G
-
S
-
S
S
A
SE
A
Q
P
F
Y
V
N
S
-
P
Y
G
-
I
T
L
A
H
N
G
N
L
T
N
A
H
E
L
R
K
K
L
F
E
E
-
K
R
R
H
I
N
T
T
S
D
S
E
I
L
L
N
I
F
A
S
E
--
L
---------
D
N
FRHYPLE
A
D
N
I
F
A
A
I
A
A
T
N
R
L
I
R
G
A
Y
A
C
V
A
M
I
--
I
G
---
H
G
M
V
A
F
R
D
P
N
G
I
R
P
L
V
L
G
K
R
D
IDEN
R
T
E
--
Y
M
V
A
S
E
S
V
A
L
D
T
L
G
F
D
F
L
R
D
V
A
P
G
E
A
I
Y
I
T
E
E
G
Q
L
F
T
R
Q
---
C
A
D
N
P
V
S
N
P
C
L
F
E
Y
V
Y
F
A
R
P
D
S
F
I
D
K
I
S
V
Y
S
A
R
V
N
M
G
T
K
L
G
E
K
I
A
R
E
---
W
EDL
D
I
D
V
V
I
P
I
P
E
T
S
C
D
I
A
L
E
I
A
R
I
L
G
K
P
Y
R
Q
G
F
V
K
N
R
Y
V
G
R
T
F
I
M
P
--
G
Q
Q
L
R
R
K
S
V
R
R
K
L
N
A
N
R
A
E
F
R
D
K
N
V
L
L
V
D
D
S
I
V
R
G
T
T
S
E
Q
I
I
E
M
A
R
E
A
G
A
K
K
V
Y
L
A
S
A
A
P
E
I
R
F
P
N
V
Y
G
I
D
M
P
S
A
T
E
L
I
A
H
G
R
E
V
D
E
I
R
Q
I
I
G
A
D
G
L
I
F
Q
D
L
N
D
L
I
D
A
V
R
A
E
--
N
P
D
I
Q
Q
F
E
C
S
V
F
N
G
V
Y
V
T
K
D
-----------
3
PsiBlast_PDB
86.73
35%
-101
- C3 -
1ECB
4
PUR1_ECOLI
A:
[1-465]
--------
C
G
I
V
G
I
A
GVMP
V
N
Q
-
S
I
Y
D
A
---
L
T
V
L
Q
H
R
G
Q
D
A
A
G
I
-
I
T
-
I
D
A
N
-
N
C
F
R
L
R
K
A
N
G
L
V
S
D
V
F
E
A
--
R
H
M
Q
R
L
Q
G
N
M
G
I
G
H
V
R
Y
P
T
A
G
-
S
-
S
S
A
SE
A
Q
P
F
Y
V
N
S
-
P
Y
G
-
I
T
L
A
H
N
G
N
L
T
N
A
H
E
L
R
K
K
L
F
E
E
-
K
R
R
H
I
N
T
T
S
D
S
E
I
L
L
N
I
F
A
S
E
--
L
---------
D
N
FRHYPLE
A
D
N
I
F
A
A
I
A
A
T
N
R
L
I
R
G
A
Y
A
C
V
A
M
I
--
I
G
---
H
G
M
V
A
F
R
D
P
N
G
I
R
P
L
V
L
G
K
R
D
IDENR
T
E
--
Y
M
V
A
S
E
S
V
A
L
D
T
L
G
F
D
F
L
R
D
V
A
P
G
E
A
I
Y
I
T
E
E
G
Q
L
F
T
R
Q
---
C
A
D
N
P
V
S
N
P
C
L
F
E
Y
V
Y
F
A
R
P
D
S
F
I
D
K
I
S
V
Y
S
A
R
V
N
M
G
T
K
L
G
E
K
I
A
R
E
---
W
EDL
D
I
D
V
V
I
P
I
P
E
T
S
C
D
I
A
L
E
I
A
R
I
L
G
K
P
Y
R
Q
G
F
V
K
N
R
Y
V
G
R
T
F
I
M
P
--------
K
S
V
R
R
K
L
N
A
N
R
A
E
F
R
D
K
N
V
L
L
V
D
D
S
I
V
R
G
T
T
S
E
Q
I
I
E
M
A
R
E
A
G
A
K
K
V
Y
L
A
S
A
A
P
E
I
R
F
P
N
V
Y
G
I
D
M
P
S
A
T
E
L
I
A
H
G
R
E
V
D
E
I
R
Q
I
I
G
A
D
G
L
I
F
Q
D
L
N
D
L
I
D
A
V
R
A
E
--
N
P
D
I
Q
Q
F
E
C
S
V
F
N
G
V
Y
V
T
K
D
-----------
21
PsiBlast_CBE
86.66
35%
-99
- C3 -
1ECG
4
PUR1_ECOLI
B:
[1-465]
--------
C
G
I
V
G
I
A
GVMP
V
N
Q
-
S
I
Y
D
A
---
L
T
V
L
Q
H
R
G
Q
D
A
A
G
I
-
I
T
-
I
D
A
N
-
N
C
F
R
L
R
K
A
N
G
L
V
S
D
V
F
E
A
--
R
H
M
Q
R
L
Q
G
N
M
G
I
G
H
V
R
Y
P
T
A
G
-
S
-
S
S
A
SE
A
Q
P
F
Y
V
N
S
-
P
Y
G
-
I
T
L
A
H
N
G
N
L
T
N
A
H
E
L
R
K
K
L
F
E
E
-
K
R
R
H
I
N
T
T
S
D
S
E
I
L
L
N
I
F
A
S
E
--
L
---------
D
N
FRHYPLEAD
N
I
F
A
A
I
A
A
T
N
R
L
I
R
G
A
Y
A
C
V
A
M
I
--
I
G
---
H
G
M
V
A
F
R
D
P
N
G
I
R
P
L
V
L
G
K
R
D
IDENR
T
E
--
Y
M
V
A
S
E
S
V
A
L
D
T
L
G
F
D
F
L
R
D
V
A
P
G
E
A
I
Y
I
T
E
E
G
Q
L
F
T
R
Q
---
C
A
D
N
P
V
S
N
P
C
L
F
E
Y
V
Y
F
A
R
P
D
S
F
I
D
K
I
S
V
Y
S
A
R
V
N
M
G
T
K
L
G
E
K
I
A
R
E
---
W
EDL
D
I
D
V
V
I
P
I
P
E
T
S
C
D
I
A
L
E
I
A
R
I
L
G
K
P
Y
R
Q
G
F
V
K
N
R
Y
V
G
R
T
F
I
M
P
--
G
Q
Q
L
R
R
K
S
V
R
R
K
L
N
A
N
R
A
E
F
R
D
K
N
V
L
L
V
D
D
S
I
V
R
G
T
T
S
E
Q
I
I
E
M
A
R
E
A
G
A
K
K
V
Y
L
A
S
A
A
P
E
I
R
F
P
N
V
Y
G
I
D
M
P
S
A
T
E
L
I
A
H
G
R
E
V
D
E
I
R
Q
I
I
G
A
D
G
L
I
F
Q
D
L
N
D
L
I
D
A
V
R
A
E
--
N
P
D
I
Q
Q
F
E
C
S
V
F
N
G
V
Y
V
T
K
D
-----------
20
PsiBlast_CBE
86.58
35%
-99
- C3 -
1ECJ
1
PUR1_ECOLI
C:
[1-465]
--------
C
G
I
V
G
I
A
GVMP
V
N
Q
-
S
I
Y
D
A
---
L
T
V
L
Q
H
R
G
Q
D
A
A
G
I
-
I
T
-
I
D
A
N
-
N
C
F
R
L
R
K
A
N
G
L
V
S
D
V
F
E
A
--
R
H
M
Q
R
L
Q
G
N
M
G
I
G
H
V
R
Y
P
T
A
G
-
S
-
S
S
A
SE
A
Q
P
F
Y
V
N
S
-
P
Y
G
-
I
T
L
A
H
N
G
N
L
T
N
A
H
E
L
R
K
K
L
F
E
E
-
K
R
R
H
I
N
T
T
S
D
S
E
I
L
L
N
I
F
A
S
E
--
L
---------
D
N
FRHYPLEAD
N
I
F
A
A
I
A
A
T
N
R
L
I
R
G
A
Y
A
C
V
A
M
I
--
I
G
---
H
G
M
V
A
F
R
D
P
N
G
I
R
P
L
V
L
G
K
R
D
IDENR
T
E
--
Y
M
V
A
S
E
S
V
A
L
D
T
L
G
F
D
F
L
R
D
V
A
P
G
E
A
I
Y
I
T
E
E
G
Q
L
F
T
R
Q
---
C
A
D
N
P
V
S
N
P
C
L
F
E
Y
V
Y
F
A
R
P
D
S
F
I
D
K
I
S
V
Y
S
A
R
V
N
M
G
T
K
L
G
E
K
I
A
R
E
---
W
EDL
D
I
D
V
V
I
P
I
P
E
T
S
C
D
I
A
L
E
I
A
R
I
L
G
K
P
Y
R
Q
G
F
V
K
N
R
Y
V
G
R
T
F
I
M
P
--
G
Q
Q
L
R
R
K
S
V
R
R
K
L
N
A
N
R
A
E
F
R
D
K
N
V
L
L
V
D
D
S
I
V
R
G
T
T
S
E
Q
I
I
E
M
A
R
E
A
G
A
K
K
V
Y
L
A
S
A
A
P
E
I
R
F
P
N
V
Y
G
I
D
M
P
S
A
T
E
L
I
A
H
G
R
E
V
D
E
I
R
Q
I
I
G
A
D
G
L
I
F
Q
D
L
N
D
L
I
D
A
V
R
A
E
--
N
P
D
I
Q
Q
F
E
C
S
V
F
N
G
V
Y
V
T
K
D
-----------
22
PsiBlast_CBE
86.53
35%
-98
- C3 -
1ECF
3
PUR1_ECOLI
B:
[1-465]
--------
C
G
I
V
G
I
A
GVMP
V
N
Q
-
S
I
Y
D
A
---
L
T
V
L
Q
H
R
G
Q
D
A
A
G
I
-
I
T
-
I
D
A
N
-
N
C
F
R
L
R
K
A
N
G
L
V
S
D
V
F
E
A
--
R
H
M
Q
R
L
Q
G
N
M
G
I
G
H
V
R
Y
P
T
A
G
-
S
-
S
S
A
SE
A
Q
P
F
Y
V
N
S
-
P
Y
G
-
I
T
L
A
H
N
G
N
L
T
N
A
H
E
L
R
K
K
L
F
E
E
-
K
R
R
H
I
N
T
T
S
D
S
E
I
L
L
N
I
F
A
S
E
--
L
---------
D
N
FRHYPLEAD
N
I
F
A
A
I
A
A
T
N
R
L
I
R
G
A
Y
A
C
V
A
M
I
--
I
G
---
H
G
M
V
A
F
R
D
P
N
G
I
R
P
L
V
L
G
K
R
D
IDENR
T
E
--
Y
M
V
A
S
E
S
V
A
L
D
T
L
G
F
D
F
L
R
D
V
A
P
G
E
A
I
Y
I
T
E
E
G
Q
L
F
T
R
Q
---
C
A
D
N
P
V
S
N
P
C
L
F
E
Y
V
Y
F
A
R
P
D
S
F
I
D
K
I
S
V
Y
S
A
R
V
N
M
G
T
K
L
G
E
K
I
A
R
E
---
W
EDL
D
I
D
V
V
I
P
I
P
E
T
S
C
D
I
A
L
E
I
A
R
I
L
G
K
P
Y
R
Q
G
F
V
K
N
R
Y
V
G
R
T
F
I
M
P
--
G
Q
Q
L
R
R
K
S
V
R
R
K
L
N
A
N
R
A
E
F
R
D
K
N
V
L
L
V
D
D
S
I
V
R
G
T
T
S
E
Q
I
I
E
M
A
R
E
A
G
A
K
K
V
Y
L
A
S
A
A
P
E
I
R
F
P
N
V
Y
G
I
D
M
P
S
A
T
E
L
I
A
H
G
R
E
V
D
E
I
R
Q
I
I
G
A
D
G
L
I
F
Q
D
L
N
D
L
I
D
A
V
R
A
E
--
N
P
D
I
Q
Q
F
E
C
S
V
F
N
G
V
Y
V
T
K
D
-----------
26
PsiBlast_CBE
86.09
35%
-101
- C3 -
1ECB
4
PUR1_ECOLI
B:
[1-465]
--------
C
G
I
V
G
I
A
GVMP
V
N
Q
-
S
I
Y
D
A
---
L
T
V
L
Q
H
R
G
Q
D
A
A
G
I
-
I
T
-
I
D
A
N
-
N
C
F
R
L
R
K
A
N
G
L
V
S
D
V
F
E
A
--
R
H
M
Q
R
L
Q
G
N
M
G
I
G
H
V
R
Y
P
T
A
G
-
S
-
S
S
A
SE
A
Q
P
F
Y
V
N
S
-
P
Y
G
-
I
T
L
A
H
N
G
N
L
T
N
A
H
E
L
R
K
K
L
F
E
E
-
K
R
R
H
I
N
T
T
S
D
S
E
I
L
L
N
I
F
A
S
E
--
L
---------
D
N
FRHYPLE
A
D
N
I
F
A
A
I
A
A
T
N
R
L
I
R
G
A
Y
A
C
V
A
M
I
--
I
G
---
H
G
M
V
A
F
R
D
P
N
G
I
R
P
L
V
L
G
K
R
D
IDEN
R
T
E
--
Y
M
V
A
S
E
S
V
A
L
D
T
L
G
F
D
F
L
R
D
V
A
P
G
E
A
I
Y
I
T
E
E
G
Q
L
F
T
R
Q
---
C
A
D
N
P
V
S
N
P
C
L
F
E
Y
V
Y
F
A
R
P
D
S
F
I
D
K
I
S
V
Y
S
A
R
V
N
M
G
T
K
L
G
E
K
I
A
R
E
---
W
EDL
D
I
D
V
V
I
P
I
P
E
T
S
C
D
I
A
L
E
I
A
R
I
L
G
K
P
Y
R
Q
G
F
V
K
N
R
Y
V
G
R
T
F
I
M
----------
S
V
R
R
K
L
N
A
N
R
A
E
F
R
D
K
N
V
L
L
V
D
D
S
I
V
R
G
T
T
S
E
Q
I
I
E
M
A
R
E
A
G
A
K
K
V
Y
L
A
S
A
A
P
E
I
R
F
P
N
V
Y
G
I
D
M
P
S
A
T
E
L
I
A
H
G
R
E
V
D
E
I
R
Q
I
I
G
A
D
G
L
I
F
Q
D
L
N
D
L
I
D
A
V
R
A
E
--
N
P
D
I
Q
Q
F
E
C
S
V
F
N
G
V
Y
V
T
K
D
-----------
2
PsiBlast_PDB
85.91
35%
-101
- C3 -
1ECG
4
PUR1_ECOLI
A:
[1-465]
--------
C
G
I
V
G
I
A
GVMP
V
N
Q
-
S
I
Y
D
A
---
L
T
V
L
Q
H
R
G
Q
D
A
A
G
I
-
I
T
-
I
D
A
N
-
N
C
F
R
L
R
K
A
N
G
L
V
S
D
V
F
E
A
--
R
H
M
Q
R
L
Q
G
N
M
G
I
G
H
V
R
Y
P
T
A
G
-
S
-
S
S
A
SE
A
Q
P
F
Y
V
N
S
-
P
Y
G
-
I
T
L
A
H
N
G
N
L
T
N
A
H
E
L
R
K
K
L
F
E
E
-
K
R
R
H
I
N
T
T
S
D
S
E
I
L
L
N
I
F
A
S
E
--
L
---------
D
N
FRHYPLE
A
D
N
I
F
A
A
I
A
A
T
N
R
L
I
R
G
A
Y
A
C
V
A
M
I
--
I
G
---
H
G
M
V
A
F
R
D
P
N
G
I
R
P
L
V
L
G
K
R
D
IDEN
R
T
E
--
Y
M
V
A
S
E
S
V
A
L
D
T
L
G
F
D
F
L
R
D
V
A
P
G
E
A
I
Y
I
T
E
E
G
Q
L
F
T
R
Q
---
C
A
D
N
P
V
S
N
P
C
L
F
E
Y
V
Y
F
A
R
P
D
S
F
I
D
K
I
S
V
Y
S
A
R
V
N
M
G
T
K
L
G
E
K
I
A
R
E
---
W
EDL
D
I
D
V
V
I
P
I
P
E
T
S
C
D
I
A
L
E
I
A
R
I
L
G
K
P
Y
R
Q
G
F
V
K
N
R
Y
V
G
R
T
F
I
M
P
--
G
Q
Q
L
R
R
K
S
V
R
R
K
L
N
A
N
R
A
E
F
R
D
K
N
V
L
L
V
D
D
S
I
V
R
G
T
T
S
E
Q
I
I
E
M
A
R
E
A
G
A
K
K
V
Y
L
A
S
A
A
P
E
I
R
F
P
N
V
Y
G
I
D
M
P
S
A
T
E
L
I
A
H
G
R
E
V
D
E
I
R
Q
I
I
G
A
D
G
L
I
F
Q
D
L
N
D
L
I
D
A
V
R
A
E
--
N
P
D
I
Q
Q
F
E
C
S
V
F
N
G
V
Y
V
T
K
D
-----------
24
PsiBlast_CBE
85.54
35%
-103
- C3 -
1ECB
4
PUR1_ECOLI
D:
[1-465]
--------
C
G
I
V
G
I
A
GVMP
V
N
Q
-
S
I
Y
D
A
---
L
T
V
L
Q
H
R
G
Q
D
A
A
G
I
-
I
T
-
I
D
A
N
-
N
C
F
R
L
R
K
A
N
G
L
V
S
D
V
F
E
A
--
R
H
M
Q
R
L
Q
G
N
M
G
I
G
H
V
R
Y
P
T
A
G
-
S
-
S
S
A
SE
A
Q
P
F
Y
V
N
S
-
P
Y
G
-
I
T
L
A
H
N
G
N
L
T
N
A
H
E
L
R
K
K
L
F
E
E
-
K
R
R
H
I
N
T
T
S
D
S
E
I
L
L
N
I
F
A
S
E
--
L
---------
D
N
FRHYPLEAD
N
I
F
A
A
I
A
A
T
N
R
L
I
R
G
A
Y
A
C
V
A
M
I
--
I
G
---
H
G
M
V
A
F
R
D
P
N
G
I
R
P
L
V
L
G
K
R
D
IDENR
T
E
--
Y
M
V
A
S
E
S
V
A
L
D
T
L
G
F
D
F
L
R
D
V
A
P
G
E
A
I
Y
I
T
E
E
G
Q
L
F
T
R
Q
---
C
A
D
N
P
V
S
N
P
C
L
F
E
Y
V
Y
F
A
R
P
D
S
F
I
D
K
I
S
V
Y
S
A
R
V
N
M
G
T
K
L
G
E
K
I
A
R
E
---
W
EDL
D
I
D
V
V
I
P
I
P
E
T
S
C
D
I
A
L
E
I
A
R
I
L
G
K
P
Y
R
Q
G
F
V
K
N
R
Y
V
G
R
T
F
I
M
----------
S
V
R
R
K
L
N
A
N
R
A
E
F
R
D
K
N
V
L
L
V
D
D
S
I
V
R
G
T
T
S
E
Q
I
I
E
M
A
R
E
A
G
A
K
K
V
Y
L
A
S
A
A
P
E
I
R
F
P
N
V
Y
G
I
D
M
P
S
A
T
E
L
I
A
H
G
R
E
V
D
E
I
R
Q
I
I
G
A
D
G
L
I
F
Q
D
L
N
D
L
I
D
A
V
R
A
E
--
N
P
D
I
Q
Q
F
E
C
S
V
F
N
G
V
Y
V
T
K
D
-----------
5
PsiBlast_PDB
85.21
35%
-99
- C3 -
1ECJ
1
PUR1_ECOLI
A:
[1-465]
--------
C
G
I
V
G
I
A
GVMP
V
N
Q
-
S
I
Y
D
A
---
L
T
V
L
Q
H
R
G
Q
D
A
A
G
I
-
I
T
-
I
D
A
N
-
N
C
F
R
L
R
K
A
N
G
L
V
S
D
V
F
E
A
--
R
H
M
Q
R
L
Q
G
N
M
G
I
G
H
V
R
Y
P
T
A
G
-
S
-
S
S
A
SE
A
Q
P
F
Y
V
N
S
-
P
Y
G
-
I
T
L
A
H
N
G
N
L
T
N
A
H
E
L
R
K
K
L
F
E
E
-
K
R
R
H
I
N
T
T
S
D
S
E
I
L
L
N
I
F
A
S
E
--
L
---------
D
N
FRHYPLE
A
D
N
I
F
A
A
I
A
A
T
N
R
L
I
R
G
A
Y
A
C
V
A
M
I
--
I
G
---
H
G
M
V
A
F
R
D
P
N
G
I
R
P
L
V
L
G
K
R
D
IDEN
R
T
E
--
Y
M
V
A
S
E
S
V
A
L
D
T
L
G
F
D
F
L
R
D
V
A
P
G
E
A
I
Y
I
T
E
E
G
Q
L
F
T
R
Q
---
C
A
D
N
P
V
S
N
P
C
L
F
E
Y
V
Y
F
A
R
P
D
S
F
I
D
K
I
S
V
Y
S
A
R
V
N
M
G
T
K
L
G
E
K
I
A
R
E
---
W
EDL
D
I
D
V
V
I
P
I
P
E
T
S
C
D
I
A
L
E
I
A
R
I
L
G
K
P
Y
R
Q
G
F
V
K
N
R
Y
V
G
R
T
F
I
M
P
--
G
Q
Q
L
R
R
K
S
V
R
R
K
L
N
A
N
R
A
E
F
R
D
K
N
V
L
L
V
D
D
S
I
V
R
G
T
T
S
E
Q
I
I
E
M
A
R
E
A
G
A
K
K
V
Y
L
A
S
A
A
P
E
I
R
F
P
N
V
Y
G
I
D
M
P
S
A
T
E
L
I
A
H
G
R
E
V
D
E
I
R
Q
I
I
G
A
D
G
L
I
F
Q
D
L
N
D
L
I
D
A
V
R
A
E
--
N
P
D
I
Q
Q
F
E
C
S
V
F
N
G
V
Y
V
T
K
D
-----------
10
PsiBlast_PDB
61.50
29%
-101
- C3 -
1XFG
3
GLMS_ECOLI
A:
[1-217]
--------
C
G
I
V
G
A
I
----
A
Q
R
D
V
A
E
I
L
L
E
G
L
R
R
L
E
Y
R
G
Y
D
S
A
G
L
A
V
V
-
D
A
-
E
-
G
H
M
T
R
L
R
R
L
G
K
V
Q
M
L
A
Q
A
A
E
E
--
H
P
L
H
G
G
T
G
I
A
H
T
R
W
A
T
H
G
-
E
-
P
S
E
--
V
N
A
H
P
H
V
S
E
H
I
---
V
V
V
H
N
G
I
I
E
N
H
E
P
L
R
E
E
L
K
A
R
-
G
Y
T
-
F
V
S
E
T
D
T
E
V
I
A
H
L
V
N
W
E
--
L
---------
K
Q
GG-------
T
L
R
E
A
V
L
R
A
I
P
Q
L
R
G
A
Y
G
T
V
I
-
M
--
D
S
RHP
D
T
L
L
A
A
R
S
G
S
---
P
L
V
I
G
L
G
M
-----
G
E
--
N
F
I
A
S
D
Q
L
A
L
L
P
V
T
R
R
F
I
F
-
L
E
E
G
D
I
A
E
I
T
R
R
S
V
N
I
F
D
K
---
T
G
A
E
V
K
R
Q
D
I
E
S
N
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
61.19
29%
-100
- C3 -
1XFF
3
GLMS_ECOLI
A:
[1-217]
--------
C
G
I
V
G
A
I
----
A
Q
R
D
V
A
E
I
L
L
E
G
L
R
R
L
E
Y
R
G
Y
D
S
A
G
L
A
V
V
-
D
A
-
E
-
G
H
M
T
R
L
R
R
L
G
K
V
Q
M
L
A
Q
A
A
E
E
--
H
P
L
H
G
G
T
G
I
A
H
T
R
W
A
T
H
G
-
E
-
P
S
E
--
V
N
A
H
P
H
V
S
E
H
I
---
V
V
V
H
N
G
I
I
E
N
H
E
P
L
R
E
E
L
K
A
R
-
G
Y
T
-
F
V
S
E
T
D
T
E
V
I
A
H
L
V
N
W
E
--
L
---------
K
Q
GG-------
T
L
R
E
A
V
L
R
A
I
P
Q
L
R
G
A
Y
G
T
V
I
-
M
--
D
S
RHP
D
T
L
L
A
A
R
S
G
S
---
P
L
V
I
G
L
G
M
-----
G
E
--
N
F
I
A
S
D
Q
L
A
L
L
P
V
T
R
R
F
I
F
-
L
E
E
G
D
I
A
E
I
T
R
R
S
V
N
I
F
D
K
---
T
G
A
E
V
K
R
Q
D
I
E
S
N
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
HHSearch
59.53
28%
-94
- C3 -
1XFF
3
GLMS_ECOLI
A:
[1-222]
--------
C
G
I
V
G
A
I
----
A
Q
R
D
V
A
E
I
L
L
E
G
L
R
R
L
E
Y
R
G
Y
D
S
A
G
L
-
A
V
-
V
D
A
E
-
G
H
M
T
R
L
R
R
L
G
K
V
Q
M
L
A
Q
--
A
A
E
E
H
P
L
H
G
G
T
G
I
A
H
T
R
W
A
T
H
G
E
P
S
E
V
N
--
A
H
P
H
V
S
-----
E
H
I
V
V
V
H
N
G
I
I
E
N
H
E
P
L
R
E
E
L
K
A
R
-
G
Y
T
-
F
V
S
E
T
D
T
E
V
I
A
H
L
V
N
W
E
L
K
Q
---------
G
G
---------
T
L
R
E
A
V
L
R
A
I
P
Q
L
R
G
A
Y
G
T
V
I
-
M
--
D
S
RHP
D
T
L
L
A
A
R
S
G
---
S
P
L
V
I
G
L
G
M
-----
G
E
--
N
F
I
A
S
D
Q
L
A
L
L
P
V
-
T
R
R
F
I
F
L
E
E
G
D
I
A
E
I
T
R
R
S
V
N
I
F
D
K
---
T
G
A
E
V
K
R
Q
D
I
E
S
N
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
57.68
28%
-100
- C3 -
4AMV
-
GLMS_ECOLI
A:
[2-217]
--------
C
G
I
V
G
A
I
----
A
Q
R
D
V
A
E
I
L
L
E
G
L
R
R
L
E
Y
R
G
Y
D
S
A
G
L
A
V
V
-
D
A
-
E
-
G
H
M
T
R
L
R
R
L
G
K
V
Q
M
L
A
Q
A
A
E
E
--
H
P
L
H
G
G
T
G
I
A
H
T
R
W
A
T
H
G
-
E
-
P
S
E
--
V
N
---
A
H
P
H
V
S
E
H
I
V
V
V
H
N
G
I
I
E
N
H
E
P
L
R
E
E
L
K
A
R
-
G
Y
T
-
F
V
S
E
T
D
T
E
V
I
A
H
L
V
N
W
E
--
L
---------
K
Q
GG-------
T
L
R
E
A
V
L
R
A
I
P
Q
L
R
G
A
Y
G
T
V
I
-
M
--
D
S
RHP
D
T
L
L
A
A
R
S
G
S
---
P
L
V
I
G
L
G
M
-----
G
E
--
N
F
I
A
S
D
Q
L
A
L
L
P
V
T
R
R
F
I
F
-
L
E
E
G
D
I
A
E
I
T
R
R
S
V
N
I
F
D
K
---
T
G
A
E
V
K
R
Q
D
I
E
S
N
L
Q
Y
D
A
G
D
K
G
I
Y
R
H
Y
M
Q
K
E
I
Y
E
Q
P
N
A
I
K
N
T
L
T
G
R
I
---
S
---
H
G
Q
V
D
L
S
E
L
G
P
N
A
D
E
L
L
S
K
V
E
H
I
Q
I
L
A
C
G
T
S
Y
N
S
G
M
V
S
R
Y
W
F
E
S
--
L
A
G
I
P
C
D
V
E
I
A
S
E
F
R
Y
R
K
S
A
V
R
R
N
S
L
M
I
T
L
S
Q
S
G
E
T
A
D
T
L
A
G
L
R
L
S
K
E
L
G
Y
L
G
S
L
A
I
C
N
V
P
G
S
S
L
V
R
E
S
D
L
A
L
M
T
N
A
G
T
E
I
G
V
A
S
T
K
A
F
T
T
Q
L
T
V
L
L
M
L
V
A
K
L
S
K
L
K
G
L
D
A
S
I
E
H
D
I
V
H
G
L
Q
A
L
P
S
R
I
E
Q
M
L
S
Q
-----------
8
PsiBlast_PDB
56.34
28%
-102
- C3 -
2J6H
1
GLMS_ECOLI
A:
[1-216]
--------
C
G
I
V
G
A
I
----
A
Q
R
D
V
A
E
I
L
L
E
G
L
R
R
L
E
Y
R
G
Y
D
S
A
G
L
A
V
V
-
D
A
-
E
-
G
H
M
T
R
L
R
R
L
G
K
V
Q
M
L
A
Q
A
A
E
E
--
H
P
L
H
G
G
T
G
I
A
H
T
R
W
A
T
H
G
-
E
-
P
S
E
--
V
N
---
A
H
P
H
V
S
E
H
I
V
V
V
H
N
G
I
I
E
N
H
E
P
L
R
E
E
L
K
A
R
-
G
Y
T
-
F
V
S
E
T
D
T
E
V
I
A
H
L
V
N
W
E
--
L
---------
K
Q
GG-------
T
L
R
E
A
V
L
R
A
I
P
Q
L
R
G
A
Y
G
T
V
I
-
M
--
D
S
RHP
D
T
L
L
A
A
R
S
G
S
---
P
L
V
I
G
L
G
M
-----
G
E
--
N
F
I
A
S
D
Q
L
A
L
L
P
V
T
R
R
F
I
F
-
L
E
E
G
D
I
A
E
I
T
R
R
S
V
N
I
F
D
K
---
T
G
A
E
V
K
R
Q
D
I
E
S
N
L
Q
Y
D
A
G
D
K
G
I
Y
R
H
Y
M
Q
K
E
I
Y
E
Q
P
N
A
I
K
N
T
L
T
G
R
I
---
S
---
H
G
Q
V
D
L
S
E
L
G
P
N
A
D
E
L
L
S
K
V
E
H
I
Q
I
L
A
C
G
T
S
Y
N
S
G
M
V
S
R
Y
W
F
E
S
--
L
A
G
I
P
C
D
V
E
I
A
S
E
F
R
Y
R
K
S
A
V
R
R
N
S
L
M
I
T
L
S
Q
S
G
E
T
A
D
T
L
A
G
L
R
L
S
K
E
L
G
Y
L
G
S
L
A
I
C
N
V
P
G
S
S
L
V
R
E
S
D
L
A
L
M
T
N
A
G
T
E
I
G
V
A
S
T
K
A
F
T
T
Q
L
T
V
L
L
M
L
V
A
K
L
S
R
L
K
G
L
D
A
S
I
E
H
D
I
V
H
G
L
Q
A
L
P
S
R
I
E
Q
M
L
S
Q
-----------
11
PsiBlast_PDB
54.69
28%
-98
- C3 -
3OOJ
1
GLMS_ECOLI
A:
[1-216]
--------
A
G
I
V
G
A
I
----
A
Q
R
D
V
A
E
I
L
L
E
G
L
R
R
L
E
Y
R
G
Y
D
S
A
G
L
A
V
V
-
D
A
-
E
-
G
H
M
T
R
L
R
R
L
G
K
V
Q
M
L
A
Q
A
A
E
E
--
H
P
L
H
G
G
T
G
I
A
H
T
R
W
A
T
H
G
-
E
-
P
S
E
--
V
N
---
A
H
P
H
V
S
E
H
I
V
V
V
H
N
G
I
I
E
N
H
E
P
L
R
E
E
L
K
A
R
-
G
Y
T
-
F
V
S
E
T
D
T
E
V
I
A
H
L
V
N
W
E
--
L
---------
K
Q
GG-------
T
L
R
E
A
V
L
R
A
I
P
Q
L
R
G
A
Y
G
T
V
I
-
M
--
D
S
RHP
D
T
L
L
A
A
R
S
G
S
---
P
L
V
I
G
L
G
M
-----
G
E
--
N
F
I
A
S
D
Q
L
A
L
L
P
V
T
R
R
F
I
F
-
L
E
E
G
D
I
A
E
I
T
R
R
S
V
N
I
F
D
K
---
T
G
A
E
V
K
R
Q
D
I
E
S
N
L
Q
Y
D
A
G
D
K
G
I
Y
R
H
Y
M
Q
K
E
I
Y
E
Q
P
N
A
I
K
N
T
L
T
G
R
I
---
S
---
H
G
Q
V
D
L
S
E
L
G
P
N
A
D
E
L
L
S
K
V
E
H
I
Q
I
L
A
C
G
T
S
Y
N
S
G
M
V
S
R
Y
W
F
E
S
--
L
A
G
I
P
C
D
V
E
I
A
S
E
F
R
Y
R
K
S
A
V
R
R
N
S
L
M
I
T
L
S
Q
S
G
E
T
A
D
T
L
A
G
L
R
L
S
K
E
L
G
Y
L
G
S
L
A
I
C
N
V
P
G
S
S
L
V
R
E
S
D
L
A
L
M
T
N
A
G
T
E
I
G
V
A
S
T
K
A
F
T
T
Q
L
T
V
L
L
M
L
V
A
K
L
S
R
L
K
G
L
D
A
S
I
E
H
D
I
V
H
G
L
Q
A
L
P
S
R
I
E
Q
M
L
S
Q
-----------