@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Wbm0285: (2015-11-30 )
MRYTGGDKREKQCFSSVDSNYNHTIKRQNFEIMKTIGTLIQEGSKLLSSHKVESPYLDCEIIMQHVLDVERSFIIMNYADQVSIKKEQLFWKLTKKRAERYPISQIIGNREFWSKNFIVNRHVLDPRADSEILVSAALKYYPNKKQEMEIADFGTGTGCLLISVLSEYEHAVGVGFEKSLKAYKVACQNMEKHNLLGRAKMFPSSWTECKGLFDLIISNPPYIRRDKLKDLQAEVQKEPKIALDGGIDGLSCYLSIFPILKRCLKKNGFAILEIGEDQNDIDKIVPSYELAFQEYMYDLAGMKRCIVIKRT
Atome Classification :
(20 SA)
---.........10........20........30........40........50........60........70........80........90........100.......110...-....120....---.---..130.......140..-.....150.......160......-.170.----......180.......190...----..---..200....----...----210--.------------.......-220...----....230.......240.....------------..250.......-----260......-...270....-..-------.-.-280...-.....290-..-......300-----------.........310-
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
---MRYTGG
D
K
R
E
K
Q
C
F
S
S
VDSNYN
H
T
I
KRQ
N
F
E
I
M
K
T
I
G
T
L
I
Q
E
G
S
K
L
L
S
SHKVESPYL
D
C
E
I
I
M
Q
H
V
L
D
V
E
R
S
F
I
I
M
NYADQ
V
S
I
K
K
E
Q
L
F
W
K
L
T
K
K
R
AERY
P
I
S
Q
I
IGNREFWSK-N
F
I
V
N
R
H
VLDP---R---A
D
S
E
I
L
V
S
A
A
L
K
YYPNK-K
Q
E
M
E
I
ADFGT
G
T
G
C
L
L
I
S
V
L
S
E
Y
-
E
H
A
VG----V
G
F
E
K
S
L
K
A
Y
K
V
A
C
QN
M
E
K
HNL----LG---RAKMFPSS
W
----
T
E
C
----
K
-
G
--
L
------------
F
D
L
I
ISN-PPY
I
R
R
----
D
K
L
K
D
L
Q
A
E
V
QKE
P
K
I
A
LDGGI------------
D
G
L
S
C
Y
L
S
I
F
P
I
-----
L
--
K
R
C
L
K
K-NG
F
A
I
-
L
E
IG-ED-------Q-N-
D
-
I
D
K
I-V
P
S
Y
E
L
-
A
-
F
Q
-
E
Y
M
Y
D
L
A-------------GM
K
R
C
I
V
I
KRT--
33
HHSearch
90.57
28%
-76
* C4 *
2B3T
1
PRMC_ECOLI
A:
[1-275]
------------------------------------
M
E
Y
Q
H
W
L
R
E
A
I
S
Q
L
Q
A
--
S
E
S
P
R
R
D
A
E
I
L
L
E
H
V
T
G
R
G
R
T
F
I
L
A
F
G
E
T
Q
L
T
D
E
Q
C
Q
Q
L
D
A
L
L
T
R
R
R
D
G
E
P
I
A
H
L
T
G
V
R
E
F
W
S
L
-
P
L
F
V
S
P
A
T
L
I
P
---
R
---
P
D
T
E
C
L
V
E
Q
A
L
A
R
L
P
E
---
Q
P
C
R
I
L
D
L
G
T
G
T
G
A
I
A
L
A
L
A
S
E
R
-
P
D
C
E
I
----
I
A
V
D
R
M
P
D
A
V
S
L
A
Q
R
N
A
Q
H
L
A
I
-----
K
---
N
I
H
I
L
Q
S
D
W
----
F
S
A
LA--
G
-
Q
--
Q
------------
F
A
M
I
V
S
N
-
P
P
Y
I
D
E
----
Q
D
P
H
L
Q
Q
G
D
V
R
F
E
P
L
T
A
L
V
A
A
D
------------
S
G
M
A
D
I
V
H
I
I
E
Q
-----
S
--
R
N
A
L
V
S
-
G
G
F
L
L
-
L
E
H
G
-
W
Q
-------
Q
-
G
E
A
-
V
R
Q
A
-
F
I
L
A
G
Y
H
D
--
V
-
E
T
C
R
D
Y
G
-------------
D
N
E
R
V
T
L
G
R
Y
Y
--
32
HHSearch
88.95
32%
-75
- C4 -
1NV8
2
PRMC_THEMA
A:
[14-282]
------------------------------------
R
K
I
W
S
L
I
R
D
C
S
G
K
L
E
G
V
-
T
E
T
S
V
L
E
V
L
L
I
V
S
R
V
L
G
I
R
K
E
D
L
F
L
K
-
D
L
G
V
S
P
T
E
E
K
R
I
L
E
L
V
E
K
R
A
S
G
Y
P
L
H
Y
I
L
G
E
K
E
F
M
G
L
-
S
F
L
V
E
E
G
V
F
V
P
---
R
---
P
E
T
E
E
L
V
E
L
A
L
E
L
I
R
K
--
Y
G
I
K
T
V
A
D
I
G
T
G
S
G
A
I
G
V
S
V
A
K
F
--
S
D
A
I
V
----
F
A
T
D
V
S
S
K
A
V
E
I
A
R
K
N
A
E
R
H
G
V
----
S
D
---
R
F
F
V
R
K
G
E
F
----
L
E
P
FKEK
F
-
A
--
S
------------
I
E
M
I
L
S
N
-
P
P
Y
V
K
S
----
S
A
--
H
L
P
K
D
V
L
F
E
P
P
E
A
L
F
G
G
E
------------
D
G
L
D
F
Y
R
E
F
F
G
-----------
R
Y
D
T
S
G
K
I
V
L
-
M
E
I
G
-
E
D
-------
Q
-
V
E
E
-
L
K
K
I
-
V
S
D
-------
T
-
V
F
L
K
D
S
A
-------------
G
K
Y
R
F
L
L
L
N
R
R
--
23
Fugue
85.39
30%
-72
- C4 -
1NV9
1
PRMC_THEMA
A:
[15-284]
-------------------------------------
K
I
W
S
L
I
R
D
C
S
G
K
L
E
G
-
V
T
E
T
S
V
L
E
V
L
L
I
V
S
R
V
L
G
I
R
K
E
D
L
F
L
K
-
D
L
G
V
S
P
T
E
E
K
R
I
L
E
L
V
E
K
R
A
S
G
Y
P
L
H
Y
I
L
G
E
K
E
F
M
G
L
-
S
F
L
V
E
E
G
V
F
V
P
---
R
---
P
E
T
E
E
L
V
E
L
A
L
E
L
I
R
K
Y
-
G
I
K
-
T
V
A
D
I
G
T
G
S
G
A
I
G
V
S
V
A
K
F
--
S
D
A
I
V
----
F
A
T
D
V
S
S
K
A
V
E
I
A
R
K
N
A
E
R
H
G
V
----
S
D
---
R
F
F
V
R
K
G
E
F
LEPF
K
E
K
----
F
-
A
--
S
------------
I
E
M
I
L
S
N
-
P
P
Y
V
K
S
----
S
A
--------
L
F
E
P
P
E
A
L
F
G
G
E
------------
D
G
L
---
D
F
Y
R
E
F
-----
F
--
G
R
Y
D
T
S
-
G
K
I
V
L
-
M
E
I
G
-
E
D
-------
Q
------
V
E
E
-
L
K
K
I
-
V
-
S
-
D
T
-
V
F
L
K
D
S
A
-------------
G
K
Y
R
F
L
L
L
N
R
R
SS
2
PsiBlast_PDB
80.66
31%
-65
- C4 -
2B3T
1
PRMC_ECOLI
A:
[18-244]
-------------------------------------------------------
E
S
P
R
R
D
A
E
I
L
L
E
H
V
T
G
R
G
R
T
F
I
L
A
F
G
E
T
Q
L
T
D
E
Q
C
Q
Q
L
D
A
L
L
T
R
R
R
D
G
E
P
I
A
H
L
T
G
V
R
E
F
W
S
L
-
P
L
F
V
S
P
A
T
L
I
P
---
R
---
P
D
T
E
C
L
V
E
Q
A
L
A
R
L
P
---
E
Q
P
C
R
I
L
D
L
G
T
G
T
G
A
I
A
L
A
L
A
S
E
R
-
P
D
C
E
I
----
I
A
V
D
R
M
P
D
A
V
S
L
A
Q
R
N
A
-
Q
H
L
A
----
I
K
---
N
I
H
I
L
Q
S
D
W
----
F
S
A
----
L
-
A
G
Q
Q
------------
F
A
M
I
V
S
N
-
P
P
Y
I
D
E
----
Q
D
P
H
L
Q
Q
G
D
V
R
F
E
P
L
T
A
L
V
A
A
D
------------
S
G
M
A
D
I
V
H
I
I
E
Q
-----
S
--
R
N
A
L
V
S
-
G
G
F
L
L
-
L
E
H
G
-
W
Q
-------
Q
-
G
-
E
-
A
V
R
Q
-
A
F
I
L
A
G
-
Y
-
H
D
-
V
E
T
C
R
D
Y
-------------
G
D
N
E
R
V
T
L
G
R
Y
--
5
PsiBlast_PDB
80.32
29%
-71
- C4 -
1SG9
2
PRMC_THEMA
A:
[29-279]
------------------------------------------------------
T
E
T
S
V
L
E
V
L
L
I
V
S
R
V
L
G
I
R
K
E
D
L
F
L
K
D
L
G
-
V
S
P
T
E
E
K
R
I
L
E
L
V
E
K
R
A
S
G
Y
P
L
H
Y
I
L
G
E
K
E
F
M
G
L
-
S
F
L
V
E
E
G
V
F
V
P
---
R
P
E
T
E
E
L
V
E
L
A
L
E
L
I
R
K
Y
G
I
K
-
T
----
V
A
D
I
G
T
G
S
G
A
I
G
V
S
V
-
A
K
F
-
S
D
A
I
V
----
F
A
T
D
V
S
S
K
A
V
E
I
A
R
K
N
A
E
R
H
G
V
SDR
F
F
V
---
R
K
G
E
F
L
E
P
F
----
K
E
K
----
F
-
A
--
S
------------
I
E
M
I
L
S
N
-
P
P
Y
V
K
S
----
S
--
A
H
L
P
K
D
V
L
F
E
P
P
E
A
L
F
G
G
E
------------
D
G
L
D
F
Y
R
E
F
F
----------
G
R
Y
D
T
S
-
G
K
I
V
L
-
M
E
I
G
-
E
D
-------
Q
V
E
-
E
-
L
K
K
I
-
V
S
D
-------
T
-
V
F
L
K
D
S
A
-------------
G
K
Y
R
F
L
L
L
N
R
R
--
4
PsiBlast_PDB
80.19
29%
-73
- C4 -
1NV9
1
PRMC_THEMA
A:
[31-281]
------------------------------------------------------
T
E
T
S
V
L
E
V
L
L
I
V
S
R
V
L
G
I
R
K
E
D
L
F
L
K
D
L
G
-
V
S
P
T
E
E
K
R
I
L
E
L
V
E
K
R
A
S
G
Y
P
L
H
Y
I
L
G
E
K
E
F
M
G
L
-
S
F
L
V
E
E
G
V
F
V
P
---
R
P
E
T
E
E
L
V
E
L
A
L
E
L
I
R
K
Y
G
I
K
-
T
----
V
A
D
I
G
T
G
S
G
A
I
G
V
S
V
-
A
K
F
-
S
D
A
I
V
----
F
A
T
D
V
S
S
K
A
V
E
I
A
R
K
N
A
E
R
H
G
V
SDR
F
F
V
---
R
K
G
E
F
L
E
P
F
----
K
E
K
----
F
-
A
--
S
------------
I
E
M
I
L
S
N
-
P
P
Y
V
K
S
----
S
--
A
------
L
F
E
P
P
E
A
L
F
G
G
E
------------
D
G
L
D
F
Y
R
E
F
F
----------
G
R
Y
D
T
S
-
G
K
I
V
L
-
M
E
I
G
-
E
D
-------
Q
V
E
-
E
-
L
K
K
I
-
V
S
D
-------
T
-
V
F
L
K
D
S
A
-------------
G
K
Y
R
F
L
L
L
N
R
R
--
6
PsiBlast_PDB
80.10
29%
-73
- C4 -
1VQ1
1
PRMC_THEMA
A:
[41-291]
------------------------------------------------------
T
E
T
S
V
L
E
V
L
L
I
V
S
R
V
L
G
I
R
K
E
D
L
F
L
K
D
L
G
-
V
S
P
T
E
E
K
R
I
L
E
L
V
E
K
R
A
S
G
Y
P
L
H
Y
I
L
G
E
K
E
F
M
G
L
-
S
F
L
V
E
E
G
V
F
V
P
---
R
P
E
T
E
E
L
V
E
L
A
L
E
L
I
R
K
Y
G
I
K
-
T
----
V
A
D
I
G
T
G
S
G
A
I
G
V
S
V
-
A
K
F
-
S
D
A
I
V
----
F
A
T
D
V
S
S
K
A
V
E
I
A
R
K
N
A
E
R
H
G
V
SDR
F
F
V
---
R
K
G
E
F
L
E
P
F
----
K
E
K
----
F
-
A
--
S
------------
I
E
M
I
L
S
N
-
P
P
Y
V
K
S
----
S
--
A
H
L
-----
F
E
P
P
E
A
L
F
G
G
E
------------
D
G
L
D
F
Y
R
E
F
F
----------
G
R
Y
D
T
S
-
G
K
I
V
L
-
M
E
I
G
-
E
D
-------
Q
V
E
-
E
-
L
K
K
I
-
V
S
D
-------
T
-
V
F
L
K
D
S
A
-------------
G
K
Y
R
F
L
L
L
N
R
R
--
22
Fugue
77.83
27%
-69
- C4 -
1T43
1
PRMC_ECOLI
A:
[2-275]
-------------------------------------
E
Y
Q
H
W
L
R
E
A
I
S
Q
L
Q
--
A
S
E
S
P
R
R
D
A
E
I
L
L
E
H
V
T
G
R
G
R
T
F
I
L
A
F
G
E
T
Q
L
T
D
E
Q
C
Q
Q
L
D
A
L
L
T
R
R
R
D
G
E
P
I
A
H
L
T
G
V
R
E
F
W
S
L
-
P
L
F
V
S
P
A
T
L
I
P
---
R
---
P
D
T
E
C
L
V
E
Q
A
L
A
R
L
P
E
Q
-
P
--
C
R
I
L
D
L
G
T
G
T
G
A
I
A
L
A
L
A
S
E
R
-
P
D
C
E
I
----
I
A
V
D
R
M
P
D
A
V
S
L
A
Q
R
N
A
Q
H
L
A
I
----
K
N
---
I
H
I
L
Q
S
D
W
F
----
S
A
L
----
A
G
Q
--
Q
------------
F
A
M
I
V
S
N
-
P
P
Y
I
D
E
----
Q
D
P
H
L
Q
Q
G
D
V
R
F
E
P
L
T
A
L
V
A
A
D
------------
S
G
M
A
D
I
V
H
I
I
E
Q
-----
S
--
R
N
A
L
V
S
-
G
G
F
L
L
-
L
E
H
G
-
W
Q
-------
Q
G
E
-
A
-
V
R
Q
A
-
F
I
L
A
G
Y
-
H
-
D
V
-
E
T
C
R
D
Y
G
-------------
D
N
E
R
V
T
L
G
R
Y
---
3
PsiBlast_PDB
77.44
29%
-70
- C4 -
1NV8
2
PRMC_THEMA
A:
[31-281]
------------------------------------------------------
T
E
T
S
V
L
E
V
L
L
I
V
S
R
V
L
G
I
R
K
E
D
L
F
L
K
D
L
G
-
V
S
P
T
E
E
K
R
I
L
E
L
V
E
K
R
A
S
G
Y
P
L
H
Y
I
L
G
E
K
E
F
M
G
L
-
S
F
L
V
E
E
G
V
F
V
P
---
R
PET
E
E
L
V
E
L
A
L
E
L
I
R
K
Y
G
I
K
-
T
----
V
A
D
I
G
T
G
S
G
A
I
G
V
S
V
-
A
K
F
-
S
D
A
I
V
----
F
A
T
D
V
S
S
K
A
V
E
I
A
R
K
N
A
E
R
H
G
V
SDR
F
F
V
---
R
K
G
E
F
L
E
P
F
----
K
E
K
----
F
-
A
--
S
------------
I
E
M
I
L
S
N
-
P
P
Y
V
K
S
----
S
--
A
H
L
P
K
D
V
L
F
E
P
P
E
A
L
F
G
G
E
------------
D
G
L
D
F
Y
R
E
F
F
----------
G
R
Y
D
T
S
-
G
K
I
V
L
-
M
E
I
G
-
E
D
-------
Q
V
E
-
E
-
L
K
K
I
-
V
S
D
-------
T
-
V
F
L
K
D
S
A
-------------
G
K
Y
R
F
L
L
L
N
R
R
--
1
PsiBlast_PDB
75.40
31%
-64
- C4 -
1T43
1
PRMC_ECOLI
A:
[18-244]
-------------------------------------------------------
E
S
P
R
R
D
A
E
I
L
L
E
H
V
T
G
R
G
R
T
F
I
L
A
F
G
E
T
Q
L
T
D
E
Q
C
Q
Q
L
D
A
L
L
T
R
R
R
D
G
E
P
I
A
H
L
T
G
V
R
E
F
W
S
L
-
P
L
F
V
S
P
A
T
L
I
P
---
R
---
P
D
T
E
C
L
V
E
Q
A
L
A
R
L
P
---
E
Q
P
C
R
I
L
D
L
G
T
G
T
G
A
I
A
L
A
L
A
S
E
R
-
P
D
C
E
I
----
I
A
V
D
R
M
P
D
A
V
S
L
A
Q
R
N
A
-
Q
H
L
A
----
I
K
---
N
I
H
I
L
Q
S
D
W
----
F
S
A
----
L
-
A
GQ
Q
------------
F
A
M
I
V
S
N
-
P
P
Y
I
D
E
----
Q
D
P
H
L
Q
Q
G
D
V
R
F
E
P
L
T
A
L
V
A
A
D
------------
S
G
M
A
D
I
V
H
I
I
E
Q
-----
S
--
R
N
A
L
V
S
-
G
G
F
L
L
-
L
E
H
G
-
W
Q
-------
Q
-
G
-
E
-
A
V
R
Q
-
A
F
I
L
A
G
-
Y
-
H
D
-
V
E
T
C
R
D
Y
-------------
G
D
N
E
R
V
T
L
G
R
Y
--
7
PsiBlast_PDB
71.58
28%
-102
- C4 -
4DZR
3
?
A:
[1-204]
------------------------------------------------------------------------------------------------------------------------
F
E
V
G
P
D
C
L
I
P
---
R
---
P
D
T
E
V
L
V
E
E
A
I
R
F
L
K
R
M
-
P
S
G
T
R
V
I
D
V
G
T
G
S
G
C
I
A
V
S
I
A
L
A
C
-
P
G
V
S
V
----
T
A
V
D
L
S
---------------------------------
W
----
A
A
A
----
D
-
G
--
I
E
W
L
I
E
R
A
E
R
GRP
W
H
A
I
V
S
N
-
P
P
Y
I
P
---------------------------------------
D
G
L
Q
F
Y
R
R
M
A
A
L
-----
P
--
P
Y
V
L
A
R
-
G
R
A
G
V
F
L
E
V
G
-
H
N
-------
Q
-
A
-
D
E
V
A
R
L
F
A
P
W
R
E
R
-
G
-
F
R
V
R
K
V
K
D
L
R
-------------
G
I
D
R
V
I
A
V
T
R
E
--
30
Fugue
60.64
21%
-44
- C4 -
4QNU
3
CMOB_ECOK1
A:
[1-323]
---------
M
I
D
F
G
N
F
Y
S
L
I
A
K
N
H
L
S
H
W
L
E
T
---
L
P
A
Q
I
A
N
W
Q
R
E
Q
Q
H
G
L
F
K
Q
W
S
N
A
V
E
F
L
P
E
I
-
K
P
Y
R
L
D
L
L
H
S
---------
V
T
A
E
S
E
E
-----
P
L
S
A
G
Q
I
K
R
I
E
T
L
M
R
N
L
M
P
W
R
K
G
P
F
S
L
Y
G
V
N
I
D
T
---
E
---
W
R
S
D
W
K
W
D
R
V
L
P
H
L
S
D
L
-
T
-
G
R
T
I
L
D
V
G
C
G
S
G
Y
H
M
W
R
M
I
G
A
G
-
A
H
-
L
A
----
V
G
I
D
P
T
---
Q
L
F
L
C
Q
F
E
A
V
R
K
L
----
L
G
NDQ
R
A
H
L
L
P
L
G
I
----
E
Q
L
----
P
-
A
--
L
KA----------
F
D
T
V
F
S
M
-
G
V
L
Y
H
R
RS
P
L
E
H
L
W
Q
L
K
D
Q
L
V
N
E
G
E
L
V
L
E
T
L
V
I
D
G
D
EN
T
V
L
V
P
G
D
R
Y
A
Q
M
R
N
V
Y
F
I
PS
A
L
A
L
--
K
N
W
L
K
K
-
C
G
F
V
D
-
I
R
I
A
-
D
V
-------
S
-
V
-
T
-
T
T
E
E
-
Q
R
R
T
E
W
-
M
-
V
T
-
E
S
L
A
D
F
L
DPHDPGKTVEGYP
A
P
K
R
A
V
L
I
A
R
K
P-
49
HHSearch
55.57
20%
-106
- C4 -
2NXC
-
PRMA_THET8
A:
[120-237]
------------------------------------------------------------------------------------------------------------------------------------------------------------
P
G
D
K
V
L
D
L
G
T
G
S
G
V
L
A
I
A
A
E
K
L
G
---
G
K
A
----
L
G
V
D
I
D
P
M
V
L
P
Q
A
E
A
N
A
K
R
N
G
V
---------
R
P
R
F
L
E
G
S
L
----
E
A
A
LP--
F
-
G
--
P
------------
F
D
L
L
V
A
N
-
L
Y
A
E
--------------------------------------------
L
H
A
A
L
A
P
R
-----
Y
--
R
E
A
L
V
P
-
G
G
R
A
L
-
L
T
G
I
L
K
D
-------
R
-
A
P
L
-
V
R
E
A
-
M
A
G
A
G
F
-
R
-
P
L
-
E
E
A
A
E
G
E
-------------
W
V
L
L
A
Y
G
R
-----
38
HHSearch
53.72
22%
-81
- C4 -
3DMG
3
?
A:
[198-342]
---------------------------------------------------------------------------------------------------------------------
Y
-
T
F
H
H
L
P
G
V
F
S
A
GKV
D
---
P
A
S
L
L
L
L
E
A
L
Q
E
R
L
G
P
E
G
V
R
G
R
Q
V
L
D
L
G
A
G
Y
G
A
L
T
L
P
L
A
R
M
G
---
A
E
V
----
V
G
V
E
D
D
L
A
S
V
L
S
L
Q
K
G
L
E
A
N
A
L
---------
K
A
Q
A
L
H
S
D
V
----
D
E
A
LTE-
E
-
A
--
R
------------
F
D
I
I
V
T
N
-
P
P
F
H
V
G
----
G
A
V
--------------------------------
I
L
D
V
A
Q
A
F
V
N
V
-----
A
--
A
A
R
L
R
P
-
G
G
V
F
F
-
L
V
S
N
-
P
F
-------
L
-
K
-
Y
-
E
P
L
L
-
E
E
K
F
G
A
-
F
-
Q
T
-
L
K
V
A
E
Y
K
-------------
V
L
F
A
E
K
R
------
43
HHSearch
53.59
22%
-76
- C4 -
3TM4
1
?
A:
[205-344]
---------------------------------------------------------------------------------------------------------------------------------------------
S
I
A
N
A
M
I
E
L
A
E
L
---
D
G
G
S
V
L
D
P
M
C
G
S
G
T
I
L
I
E
L
A
L
R
R
-
Y
S
G
E
I
----
I
G
I
E
K
Y
R
K
H
L
I
G
A
E
M
N
A
L
A
A
G
V
----
L
D
---
K
I
K
F
I
Q
G
D
A
----
T
Q
L
SQY-
V
-
D
--
S
------------
V
D
F
A
I
S
N
-
L
P
Y
G
----------
S
-----------------------------
M
I
P
D
L
Y
M
K
F
F
N
E
-----
L
--
A
K
V
L
E
K
-
R
G
V
F
I
-
T
T
E
K
-
K
------------
A
-
I
E
E
A
-
I
A
E
N
G
F
-
E
-
I
I
-
H
H
R
V
I
G
H
-------------
G
G
L
M
V
H
L
Y
V
V
K
--
51
HHSearch
50.59
15%
-93
- C4 -
3A27
1
TYW2_METJA
A:
[119-243]
------------------------------------------------------------------------------------------------------------------------------------------------------------
E
N
E
V
V
V
D
M
F
A
G
I
G
Y
F
T
I
P
L
A
K
Y
S
-
K
P
K
L
V
----
Y
A
I
E
K
N
P
T
A
Y
H
Y
L
C
E
N
I
K
L
N
K
L
-----
N
---
N
V
I
P
I
L
A
D
N
----
R
D
V
E
L
--
K
-
D
--
V
------------
A
D
R
V
I
M
G
-
Y
V
H
K
---------------------------------------------
T
H
K
F
L
D
K
-----
T
--
F
E
F
L
K
D
-
R
G
V
I
H
-
Y
H
E
T
-
V
A
EKIMYE
R
P
-
I
E
R
-
L
K
F
Y
-
A
E
K
N
G
Y
-
K
-
L
I
-
D
Y
E
V
R
K
I
-------------
K
K
Y
A
P
G
V
W
H
V
V
--
41
HHSearch
49.31
17%
-79
- C4 -
3TMA
-
?
A:
[186-321]
-----------------------------------------------------------------------------------------------------------------------------------------
S
L
T
P
V
L
A
Q
A
L
L
R
L
A
D
A
--
R
P
G
M
R
V
L
D
P
F
T
G
S
G
T
I
A
L
E
A
A
S
T
L
G
P
T
S
P
V
----
Y
A
G
D
L
D
E
K
R
L
G
L
A
R
E
A
A
L
A
S
G
L
-----
S
---
W
I
R
F
L
R
A
D
A
----
R
H
L
PRF-
F
-
P
--
E
------------
V
D
R
I
L
A
N
-
P
P
H
G
L
--------
K
-----------------
E
------------
G
L
F
H
L
Y
W
D
F
L
R
G
-----
A
--
L
A
L
L
P
P
-
G
G
R
V
A
-
L
L
T
L
-
R
P
-------
A
-
L
-
L
-
K
R
A
L
-
P
P
G
F
A
L
-
R
-
H
A
-
R
V
V
E
Q
G
G
-------------
V
Y
P
R
V
F
V
L
E
K
L
--
27
Fugue
47.56
13%
-61
- C4 -
1UFK
-
PRMA_THET8
A:
[1-254]
M
W
V
Y
R
L
K
G
T
L
E
A
L
D
P
I
L
P
G
L
F
D
G
G
A
R
G
L
W
E
R
E
G
E
V
W
A
F
F
P
A
P
V
D
L
P
Y
E
G
V
W
E
E
V
G
D
E
D
W
L
E
A
W
R
R
D
L
K
P
A
L
A
P
P
F
V
V
L
A
P
W
---------------
H
T
W
E
G
A
E
I
P
L
V
I
E
P
G
H
-------------------------
H
E
T
T
R
L
A
L
K
A
L
A
R
H
L
R
P
-
G
D
--
K
V
L
D
L
G
T
G
S
G
--
V
L
A
I
A
A
E
K
-
L
G
G
K
A
----
L
G
V
D
I
D
P
M
V
L
P
Q
A
E
A
N
A
K
R
N
G
V
----
R
P
---
R
F
L
E
G
S
L
E
A
----
A
L
P
----
F
-
G
--
P
------------
F
D
L
L
V
A
N
-
L
Y
--------------------------------------------
A
E
L
H
A
A
L
A
P
R
-----
Y
--
R
E
A
L
V
P
-
G
G
R
A
L
-
L
T
-
G
-
I
L
-------
K
-
D
-
R
-
A
P
L
V
-
R
E
A
M
A
G
-
A
G
F
R
-
P
L
E
E
A
A
E
-------------
G
E
W
V
L
L
A
Y
G
R
---
9
PsiBlast_PDB
47.18
26%
-63
- C4 -
3GRZ
2
PRMA_LACDB
A:
[62-179]
--------------------------------------------------------------------------------------------------------------------------------------------------------------
L
T
V
A
D
V
G
T
G
S
G
I
L
A
I
A
A
------
H
K
L
G
AK
S
V
L
A
T
D
I
S
D
E
S
M
T
A
A
E
E
N
A
A
L
N
G
I
----
Y
D
---
I
A
L
Q
K
T
S
L
L
----
A
D
V
----
D
-
G
--
K
------------
F
D
L
I
V
A
N
I
L
A
E
I
L
L
----
D
L
I
P
Q
L
D
S
H
L
N
E
D
G
Q
V
I
F
-
S
G
I
------------
D
----
Y
L
Q
L
-
P
K
-----
I
--
E
Q
A
L
A
E
-
N
S
F
Q
I
-
D
L
K
M
-
R
A
-------
G
-
R
-
W
-
I
G
L
A
-
I
S
R
K
H
----------------------------------------
47
HHSearch
46.82
21%
-78
- C4 -
2ESR
-
?
A:
[18-142]
----------------------------------------------------------------------------------------------------------------------------------------------
V
R
G
A
I
F
N
M
I
G
P
Y
-
F
N
G
G
R
V
L
D
L
F
A
G
S
G
G
L
A
I
E
A
V
S
R
G
-
M
-
S
A
A
----
V
L
V
E
K
N
R
K
A
Q
A
I
I
Q
D
N
I
I
M
T
K
A
----
E
N
---
R
F
T
L
L
K
M
E
A
----
E
R
A
I
D
C
L
T
-
G
--
R
------------
F
D
L
V
F
L
D
-
P
P
Y
A
K
E
----
T
--------------------------------------
I
V
A
T
I
E
A
-----
L
A
A
K
N
L
L
S
E
-
Q
V
M
V
V
-
C
E
T
D
-
K
T
-------
V
-
L
-
L
-
P
K
E
I
-
A
T
L
G
I
W
-
K
-
E
K
-
I
Y
G
I
S
K
V
-------------
T
V
Y
V
N
E
G
H
H
H
H
--