@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Wbm0318: (2015-11-30 )
MYYDDGIPVFDSLDKLTKPNSMKVVSSDSSEKGDIVLEPLESGFALTLGNALRRVMLSSLIGSAVYGIKIDGITHEFTSIQGVREDVTDIVLNMGMLRCKLNGTSNKCLSLSAKGPCQVLAGMIETDDQCSIVNKDLLICTLGQDVELNMTIYVASGKGYLPVTKYKENEFLKPMNEQDLISFIPVNALYSPINRVSYRVENSRVGQVTDKDKLILSVETDGTISPSQAVDSAARILQEQLQPFISSDISYKKSQVSSPSGYKDLGYDPILLRKVDEMELSVRSHNCLKNENITYIGDLVQKTESEMLRTANFGRKSLNEIKAVLNNFGLSLGMDIPDWPPKDIDELARQHTDED
Atome Classification :
(22 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140-.-.-.....150.......160.-......170.......180.......190.......200.......210.......220.......230.......240....-...250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350...
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MYYDDGI
P
V
F
D
S
L
D
K
LTKPN
S
M
K
V
V
SSDSSEKG
D
I
V
L
EPLESGF
A
L
T
L
G
N
A
L
R
R
V
M
L
S
S
L
I
GS
A
V
Y
G
I
K
IDGITH
E
F
T
S
I
Q
G
V
R
E
D
V
T
D
I
V
L
NM
G
M
L
R
C
K
LNGTSN
K
C
L
S
LSAK
G
P
C
Q
V
L
A
G
M
IETDDQCSIVNK
D
L
L
I
C
TL-G-Q-
D
V
E
L
N
M
T
I
Y
V
ASGKG
Y
L
PV-TKYKENEFLKPM
N
E
Q
D
L
I
S
F
I
P
V
N
A
L
Y
S
P
I
N
R
V
S
Y
R
VENSRVGQVTDKD
K
L
I
L
S
V
ETDGTIS
P
S
Q
A
V
D
S
A
A
R
I
L
Q
E
Q
L
Q
P
F
I
S-SDISYKKSQVSSPSGYKDLGYD
P
I
L
L
R
K
V
D
E
M
E
L
S
VRSHNCLKNEN
I
T
Y
I
G
D
L
V
Q
K
T
E
S
E
M
L
R
T
ANF
G
R
K
S
L
N
E
I
K
A
V
L
N
NFGLSLGMDIPDWP
P
K
D
I
D
E
L
A
R
QHTDED
4
PsiBlast_PDB
93.81
45%
-119
- C3 -
4JK2
-
RPOA_ECOLI
A:
[20-325]
----------------------------
S
S
T
H
A
K
V
T
L
E
P
L
E
R
G
F
G
H
T
L
G
N
A
L
R
R
I
L
L
S
S
M
P
G
C
A
V
T
E
V
E
I
D
G
V
L
H
E
Y
S
T
K
E
G
V
Q
E
D
I
L
E
I
L
L
N
L
K
G
L
A
V
R
V
Q
G
K
D
E
V
I
L
T
L
N
K
S
G
I
G
P
V
T
A
A
D
I
T
H
D
G
D
V
E
I
V
K
P
Q
H
V
I
C
H
L
-
T
D
E
-
N
A
S
I
S
M
R
I
K
V
Q
R
G
R
G
Y
V
P
A
S
T
R
I
H
S
E
E
D
E
R
P
------
I
G
R
L
L
V
D
A
C
Y
S
P
V
E
R
I
A
Y
N
V
E
A
A
R
V
E
Q
R
T
D
L
D
K
L
V
I
E
M
E
T
N
G
T
I
D
P
E
E
A
I
R
R
A
A
T
I
L
A
E
Q
L
E
A
F
V
D
L
R
D
V
R
Q
P
E
V
K
E
E
K
P
E
------
F
D
P
I
L
L
R
P
V
D
D
L
E
L
T
V
R
S
A
N
C
L
K
A
E
A
I
H
Y
I
G
D
L
V
Q
R
T
E
V
E
L
L
K
T
P
N
L
G
K
K
S
L
T
E
I
K
D
V
L
A
S
R
G
L
S
L
G
M
R
L
E
N
W
P
P
A
S
------------
8
PsiBlast_PDB
93.48
45%
-120
- C3 -
4KN7
-
RPOA_ECOLI
A:
[20-325]
----------------------------
S
S
T
H
A
K
V
T
L
E
P
L
E
R
G
F
G
H
T
L
G
N
A
L
R
R
I
L
L
S
S
M
P
G
C
A
V
T
E
V
E
I
D
G
V
L
H
E
Y
S
T
K
E
G
V
Q
E
D
I
L
E
I
L
L
N
L
K
G
L
A
V
R
V
Q
G
K
D
E
V
I
L
T
L
N
K
S
G
I
G
P
V
T
A
A
D
I
T
H
D
G
D
V
E
I
V
K
P
Q
H
V
I
C
H
L
-
T
D
E
-
N
A
S
I
S
M
R
I
K
V
Q
R
G
R
G
Y
V
P
A
S
T
R
I
H
S
E
E
D
E
R
P
------
I
G
R
L
L
V
D
A
C
Y
S
P
V
E
R
I
A
Y
N
V
E
A
A
R
V
E
Q
R
T
D
L
D
K
L
V
I
E
M
E
T
N
G
T
I
D
P
E
E
A
I
R
R
A
A
T
I
L
A
E
Q
L
E
A
F
V
D
L
R
D
V
R
Q
P
E
V
K
E
E
K
P
E
------
F
D
P
I
L
L
R
P
V
D
D
L
E
L
T
V
R
S
A
N
C
L
K
A
E
A
I
H
Y
I
G
D
L
V
Q
R
T
E
V
E
L
L
K
T
P
N
L
G
K
K
S
L
T
E
I
K
D
V
L
A
S
R
G
L
S
L
G
M
R
L
E
N
W
P
P
A
S
------------
16
PsiBlast_PDB
93.36
45%
-132
- C3 -
4MEY
-
RPOA_ECOLI
A:
[26-330]
----------------------------
S
S
T
H
A
K
V
T
L
E
P
L
E
R
G
F
G
H
T
L
G
N
A
L
R
R
I
L
L
S
S
M
P
G
C
A
V
T
E
V
E
I
D
G
V
L
H
E
Y
S
T
K
E
G
V
Q
E
D
I
L
E
I
L
L
N
L
K
G
L
A
V
R
V
Q
G
K
D
E
V
I
L
T
L
N
K
S
G
I
G
P
V
T
A
A
D
I
T
H
D
G
D
V
E
I
V
K
P
Q
H
V
I
C
H
L
-
T
D
E
-
N
A
S
I
S
M
R
I
K
V
Q
R
G
R
G
Y
V
P
A
S
T
R
---------------
I
G
R
L
L
V
D
A
C
Y
S
P
V
E
R
I
A
Y
N
V
E
A
A
R
V
E
Q
R
T
D
L
D
K
L
V
I
E
M
E
T
N
G
T
I
D
P
E
E
A
I
R
R
A
A
T
I
L
A
E
Q
L
E
A
F
V
D
-------------
P
E
------
F
D
P
I
L
L
R
P
V
D
D
L
E
L
T
V
R
S
A
N
C
L
K
A
E
A
I
H
Y
I
G
D
L
V
Q
R
T
E
V
E
L
L
K
T
P
N
L
G
K
K
S
L
T
E
I
K
D
V
L
A
S
R
G
L
S
L
G
M
R
L
E
N
W
P
P
A
-------------
13
PsiBlast_PDB
93.02
45%
-127
- C3 -
4YG2
-
RPOA_ECOLI
A:
[20-325]
----------------------------
S
S
T
H
A
K
V
T
L
E
P
L
E
R
G
F
G
H
T
L
G
N
A
L
R
R
I
L
L
S
S
M
P
G
C
A
V
T
E
V
E
I
D
G
V
L
H
E
Y
S
T
K
E
G
V
Q
E
D
I
L
E
I
L
L
N
L
K
G
L
A
V
R
V
Q
G
K
D
E
V
I
L
T
L
N
K
S
G
I
G
P
V
T
A
A
D
I
T
H
D
G
D
V
E
I
V
K
P
Q
H
V
I
C
H
L
-
T
D
E
-
N
A
S
I
S
M
R
I
K
V
Q
R
G
R
G
Y
V
P
A
S
T
R
I
H
S
E
E
D
E
R
P
------
I
G
R
L
L
V
D
A
C
Y
S
P
V
E
R
I
A
Y
N
V
E
A
A
R
V
E
Q
R
T
D
L
D
K
L
V
I
E
M
E
T
N
G
T
I
D
P
E
E
A
I
R
R
A
A
T
I
L
A
E
Q
L
E
A
F
V
D
L
R
D
V
R
Q
P
E
V
K
E
E
K
P
E
------
F
D
P
I
L
L
R
P
V
D
D
L
E
L
T
V
R
S
A
N
C
L
K
A
E
A
I
H
Y
I
G
D
L
V
Q
R
T
E
V
E
L
L
K
T
P
N
L
G
K
K
S
L
T
E
I
K
D
V
L
A
S
R
G
L
S
L
G
M
R
L
E
N
W
P
P
A
S
------------
3
PsiBlast_PDB
92.84
45%
-119
- C3 -
4JK1
-
RPOA_ECOLI
A:
[20-325]
----------------------------
S
S
T
H
A
K
V
T
L
E
P
L
E
R
G
F
G
H
T
L
G
N
A
L
R
R
I
L
L
S
S
M
P
G
C
A
V
T
E
V
E
I
D
G
V
L
H
E
Y
S
T
K
E
G
V
Q
E
D
I
L
E
I
L
L
N
L
K
G
L
A
V
R
V
Q
G
K
D
E
V
I
L
T
L
N
K
S
G
I
G
P
V
T
A
A
D
I
T
H
D
G
D
V
E
I
V
K
P
Q
H
V
I
C
H
L
-
T
D
E
-
N
A
S
I
S
M
R
I
K
V
Q
R
G
R
G
Y
V
P
A
S
T
R
I
H
S
E
E
D
E
R
P
------
I
G
R
L
L
V
D
A
C
Y
S
P
V
E
R
I
A
Y
N
V
E
A
A
R
V
E
Q
R
T
D
L
D
K
L
V
I
E
M
E
T
N
G
T
I
D
P
E
E
A
I
R
R
A
A
T
I
L
A
E
Q
L
E
A
F
V
D
L
R
D
V
R
Q
P
E
V
K
E
E
K
P
E
------
F
D
P
I
L
L
R
P
V
D
D
L
E
L
T
V
R
S
A
N
C
L
K
A
E
A
I
H
Y
I
G
D
L
V
Q
R
T
E
V
E
L
L
K
T
P
N
L
G
K
K
S
L
T
E
I
K
D
V
L
A
S
R
G
L
S
L
G
M
R
L
E
N
W
P
P
A
S
------------
15
PsiBlast_PDB
92.83
45%
-132
- C3 -
4MEX
-
RPOA_ECOLI
A:
[26-330]
----------------------------
S
S
T
H
A
K
V
T
L
E
P
L
E
R
G
F
G
H
T
L
G
N
A
L
R
R
I
L
L
S
S
M
P
G
C
A
V
T
E
V
E
I
D
G
V
L
H
E
Y
S
T
K
E
G
V
Q
E
D
I
L
E
I
L
L
N
L
K
G
L
A
V
R
V
Q
G
K
D
E
V
I
L
T
L
N
K
S
G
I
G
P
V
T
A
A
D
I
T
H
D
G
D
V
E
I
V
K
P
Q
H
V
I
C
H
L
-
T
D
E
-
N
A
S
I
S
M
R
I
K
V
Q
R
G
R
G
Y
V
P
A
S
T
R
---------------
I
G
R
L
L
V
D
A
C
Y
S
P
V
E
R
I
A
Y
N
V
E
A
A
R
V
E
Q
R
T
D
L
D
K
L
V
I
E
M
E
T
N
G
T
I
D
P
E
E
A
I
R
R
A
A
T
I
L
A
E
Q
L
E
A
F
V
D
-------------
P
E
------
F
D
P
I
L
L
R
P
V
D
D
L
E
L
T
V
R
S
A
N
C
L
K
A
E
A
I
H
Y
I
G
D
L
V
Q
R
T
E
V
E
L
L
K
T
P
N
L
G
K
K
S
L
T
E
I
K
D
V
L
A
S
R
G
L
S
L
G
M
R
L
E
N
W
P
P
A
-------------
7
PsiBlast_PDB
92.83
45%
-120
- C3 -
4KN4
-
RPOA_ECOLI
A:
[20-325]
----------------------------
S
S
T
H
A
K
V
T
L
E
P
L
E
R
G
F
G
H
T
L
G
N
A
L
R
R
I
L
L
S
S
M
P
G
C
A
V
T
E
V
E
I
D
G
V
L
H
E
Y
S
T
K
E
G
V
Q
E
D
I
L
E
I
L
L
N
L
K
G
L
A
V
R
V
Q
G
K
D
E
V
I
L
T
L
N
K
S
G
I
G
P
V
T
A
A
D
I
T
H
D
G
D
V
E
I
V
K
P
Q
H
V
I
C
H
L
-
T
D
E
-
N
A
S
I
S
M
R
I
K
V
Q
R
G
R
G
Y
V
P
A
S
T
R
I
H
S
E
E
D
E
R
P
------
I
G
R
L
L
V
D
A
C
Y
S
P
V
E
R
I
A
Y
N
V
E
A
A
R
V
E
Q
R
T
D
L
D
K
L
V
I
E
M
E
T
N
G
T
I
D
P
E
E
A
I
R
R
A
A
T
I
L
A
E
Q
L
E
A
F
V
D
L
R
D
V
R
Q
P
E
V
K
E
E
K
P
E
------
F
D
P
I
L
L
R
P
V
D
D
L
E
L
T
V
R
S
A
N
C
L
K
A
E
A
I
H
Y
I
G
D
L
V
Q
R
T
E
V
E
L
L
K
T
P
N
L
G
K
K
S
L
T
E
I
K
D
V
L
A
S
R
G
L
S
L
G
M
R
L
E
N
W
P
P
A
S
------------
18
PsiBlast_PDB
92.42
45%
-122
- C3 -
4ZH3
-
?
A:
[26-330]
----------------------------
S
S
T
H
A
K
V
T
L
E
P
L
E
R
G
F
G
H
T
L
G
N
A
L
R
R
I
L
L
S
S
M
P
G
C
A
V
T
E
V
E
I
D
G
V
L
H
E
Y
S
T
K
E
G
V
Q
E
D
I
L
E
I
L
L
N
L
K
G
L
A
V
R
V
Q
G
K
D
E
V
I
L
T
L
N
K
S
G
I
G
P
V
T
A
A
D
I
T
H
D
G
D
V
E
I
V
K
P
Q
H
V
I
C
H
L
-
T
D
E
-
N
A
S
I
S
M
R
I
K
V
Q
R
G
R
G
Y
V
P
A
S
T
R
I
H
S
E
E
D
E
R
P
------
I
G
R
L
L
V
D
A
C
Y
S
P
V
E
R
I
A
Y
N
V
E
A
A
R
V
E
Q
R
T
D
L
D
K
L
V
I
E
M
E
T
N
G
T
I
D
P
E
E
A
I
R
R
A
A
T
I
L
A
E
Q
L
E
A
F
---------------
P
E
------
F
D
P
I
L
L
R
P
V
D
D
L
E
L
T
V
R
S
A
N
C
L
K
A
E
A
I
H
Y
I
G
D
L
V
Q
R
T
E
V
E
L
L
K
T
P
N
L
G
K
K
S
L
T
E
I
K
D
V
L
A
S
R
G
L
S
L
G
M
R
L
E
N
W
P
P
A
-------------
17
PsiBlast_PDB
92.28
45%
-122
- C3 -
4ZH2
-
?
A:
[26-330]
----------------------------
S
S
T
H
A
K
V
T
L
E
P
L
E
R
G
F
G
H
T
L
G
N
A
L
R
R
I
L
L
S
S
M
P
G
C
A
V
T
E
V
E
I
D
G
V
L
H
E
Y
S
T
K
E
G
V
Q
E
D
I
L
E
I
L
L
N
L
K
G
L
A
V
R
V
Q
G
K
D
E
V
I
L
T
L
N
K
S
G
I
G
P
V
T
A
A
D
I
T
H
D
G
D
V
E
I
V
K
P
Q
H
V
I
C
H
L
-
T
D
E
-
N
A
S
I
S
M
R
I
K
V
Q
R
G
R
G
Y
V
P
A
S
T
R
I
H
S
E
E
D
E
R
P
------
I
G
R
L
L
V
D
A
C
Y
S
P
V
E
R
I
A
Y
N
V
E
A
A
R
V
E
Q
R
T
D
L
D
K
L
V
I
E
M
E
T
N
G
T
I
D
P
E
E
A
I
R
R
A
A
T
I
L
A
E
Q
L
E
A
F
---------------
P
E
------
F
D
P
I
L
L
R
P
V
D
D
L
E
L
T
V
R
S
A
N
C
L
K
A
E
A
I
H
Y
I
G
D
L
V
Q
R
T
E
V
E
L
L
K
T
P
N
L
G
K
K
S
L
T
E
I
K
D
V
L
A
S
R
G
L
S
L
G
M
R
L
E
N
W
P
P
A
-------------
19
PsiBlast_PDB
92.21
45%
-122
- C3 -
4ZH4
-
?
A:
[26-330]
----------------------------
S
S
T
H
A
K
V
T
L
E
P
L
E
R
G
F
G
H
T
L
G
N
A
L
R
R
I
L
L
S
S
M
P
G
C
A
V
T
E
V
E
I
D
G
V
L
H
E
Y
S
T
K
E
G
V
Q
E
D
I
L
E
I
L
L
N
L
K
G
L
A
V
R
V
Q
G
K
D
E
V
I
L
T
L
N
K
S
G
I
G
P
V
T
A
A
D
I
T
H
D
G
D
V
E
I
V
K
P
Q
H
V
I
C
H
L
-
T
D
E
-
N
A
S
I
S
M
R
I
K
V
Q
R
G
R
G
Y
V
P
A
S
T
R
I
H
S
E
E
D
E
R
P
------
I
G
R
L
L
V
D
A
C
Y
S
P
V
E
R
I
A
Y
N
V
E
A
A
R
V
E
Q
R
T
D
L
D
K
L
V
I
E
M
E
T
N
G
T
I
D
P
E
E
A
I
R
R
A
A
T
I
L
A
E
Q
L
E
A
F
---------------
P
E
------
F
D
P
I
L
L
R
P
V
D
D
L
E
L
T
V
R
S
A
N
C
L
K
A
E
A
I
H
Y
I
G
D
L
V
Q
R
T
E
V
E
L
L
K
T
P
N
L
G
K
K
S
L
T
E
I
K
D
V
L
A
S
R
G
L
S
L
G
M
R
L
E
N
W
P
P
A
-------------
6
PsiBlast_PDB
92.03
45%
-119
- C3 -
4KMU
-
RPOA_ECOLI
A:
[20-325]
----------------------------
S
S
T
H
A
K
V
T
L
E
P
L
E
R
G
F
G
H
T
L
G
N
A
L
R
R
I
L
L
S
S
M
P
G
C
A
V
T
E
V
E
I
D
G
V
L
H
E
Y
S
T
K
E
G
V
Q
E
D
I
L
E
I
L
L
N
L
K
G
L
A
V
R
V
Q
G
K
D
E
V
I
L
T
L
N
K
S
G
I
G
P
V
T
A
A
D
I
T
H
D
G
D
V
E
I
V
K
P
Q
H
V
I
C
H
L
-
T
D
E
-
N
A
S
I
S
M
R
I
K
V
Q
R
G
R
G
Y
V
P
A
S
T
R
I
H
S
E
E
D
E
R
P
------
I
G
R
L
L
V
D
A
C
Y
S
P
V
E
R
I
A
Y
N
V
E
A
A
R
V
E
Q
R
T
D
L
D
K
L
V
I
E
M
E
T
N
G
T
I
D
P
E
E
A
I
R
R
A
A
T
I
L
A
E
Q
L
E
A
F
V
D
L
R
D
V
R
Q
P
E
V
K
E
E
K
P
E
------
F
D
P
I
L
L
R
P
V
D
D
L
E
L
T
V
R
S
A
N
C
L
K
A
E
A
I
H
Y
I
G
D
L
V
Q
R
T
E
V
E
L
L
K
T
P
N
L
G
K
K
S
L
T
E
I
K
D
V
L
A
S
R
G
L
S
L
G
M
R
L
E
N
W
P
P
A
S
------------
10
PsiBlast_PDB
91.88
45%
-123
- C3 -
4YFK
-
RPOA_ECO24
A:
[20-325]
----------------------------
S
S
T
H
A
K
V
T
L
E
P
L
E
R
G
F
G
H
T
L
G
N
A
L
R
R
I
L
L
S
S
M
P
G
C
A
V
T
E
V
E
I
D
G
V
L
H
E
Y
S
T
K
E
G
V
Q
E
D
I
L
E
I
L
L
N
L
K
G
L
A
V
R
V
Q
G
K
D
E
V
I
L
T
L
N
K
S
G
I
G
P
V
T
A
A
D
I
T
H
D
G
D
V
E
I
V
K
P
Q
H
V
I
C
H
L
-
T
D
E
-
N
A
S
I
S
M
R
I
K
V
Q
R
G
R
G
Y
V
P
A
S
T
R
I
H
S
E
E
D
E
R
P
------
I
G
R
L
L
V
D
A
C
Y
S
P
V
E
R
I
A
Y
N
V
E
A
A
R
V
E
Q
R
T
D
L
D
K
L
V
I
E
M
E
T
N
G
T
I
D
P
E
E
A
I
R
R
A
A
T
I
L
A
E
Q
L
E
A
F
V
D
L
R
D
V
R
Q
P
E
V
K
E
E
K
P
E
------
F
D
P
I
L
L
R
P
V
D
D
L
E
L
T
V
R
S
A
N
C
L
K
A
E
A
I
H
Y
I
G
D
L
V
Q
R
T
E
V
E
L
L
K
T
P
N
L
G
K
K
S
L
T
E
I
K
D
V
L
A
S
R
G
L
S
L
G
M
R
L
E
N
W
P
P
A
S
------------
14
PsiBlast_PDB
88.31
45%
-121
* C3 *
5BYH
-
?
A:
[20-326]
----------------------------
S
S
T
H
A
K
V
T
L
E
P
L
E
R
G
F
G
H
T
L
G
N
A
L
R
R
I
L
L
S
S
M
P
G
C
A
V
T
E
V
E
I
D
G
V
L
H
E
Y
S
T
K
E
G
V
Q
E
D
I
L
E
I
L
L
N
L
K
G
L
A
V
R
V
Q
G
K
D
E
V
I
L
T
L
N
K
S
G
I
G
P
V
T
A
A
D
I
T
H
D
G
D
V
E
I
V
K
P
Q
H
V
I
C
H
L
-
T
D
E
-
N
A
S
I
S
M
R
I
K
V
Q
R
G
R
G
Y
V
P
A
S
T
R
I
H
S
E
E
D
E
R
P
------
I
G
R
L
L
V
D
A
C
Y
S
P
V
E
R
I
A
Y
N
V
E
A
A
R
V
E
Q
R
T
D
L
D
K
L
V
I
E
M
E
T
N
G
T
I
D
P
E
E
A
I
R
R
A
A
T
I
L
A
E
Q
L
E
A
F
V
D
L-------------
E
------
F
D
P
I
L
L
R
P
V
D
D
L
E
L
T
V
R
S
A
N
C
L
K
A
E
A
I
H
Y
I
G
D
L
V
Q
R
T
E
V
E
L
L
K
T
P
N
L
G
K
K
S
L
T
E
I
K
D
V
L
A
S
R
G
L
S
L
G
M
R
L
E
N
W
P
P
A
S
I
A
----------
1
PsiBlast_PDB
86.37
45%
-120
- C3 -
3IYD
-
RPOA_ECOLI
A:
[20-326]
----------------------------
S
S
T
H
A
K
V
T
L
E
P
L
E
R
G
F
G
H
T
L
G
N
A
L
R
R
I
L
L
S
S
M
P
G
C
A
V
T
E
V
E
I
D
G
V
L
H
E
Y
S
T
K
E
G
V
Q
E
D
I
L
E
I
L
L
N
L
K
G
L
A
V
R
V
Q
G
K
D
E
V
I
L
T
L
N
K
S
G
I
G
P
V
T
A
A
D
I
T
H
D
G
D
V
E
I
V
K
P
Q
H
V
I
C
H
L
-
T
D
E
-
N
A
S
I
S
M
R
I
K
V
Q
R
G
R
G
Y
V
P
A
S
T
R
I
-----
E
R
P
------
I
G
R
L
L
V
D
A
C
Y
S
P
V
E
R
I
A
Y
N
V
E
A
A
R
V
E
Q
R
T
D
L
D
K
L
V
I
E
M
E
T
N
G
T
I
D
P
E
E
A
I
R
R
A
A
T
I
L
A
E
Q
L
E
A
F
V
D
L
R
D
V
R
Q
P
E
V
K
E
E
K
P
E
------
F
D
P
I
L
L
R
P
V
D
D
L
E
L
T
V
R
S
A
N
C
L
K
A
E
A
I
H
Y
I
G
D
L
V
Q
R
T
E
V
E
L
L
K
T
P
N
L
G
K
K
S
L
T
E
I
K
D
V
L
A
S
R
G
L
S
L
G
M
R
L
E
N
W
P
P
A
S
I
A
D
---------
11
PsiBlast_PDB
76.23
45%
-125
- C3 -
4YFN
-
RPOA_ECO24
A:
[20-235]
----------------------------
S
S
T
H
A
K
V
T
L
E
P
L
E
R
G
F
G
H
T
L
G
N
A
L
R
R
I
L
L
S
S
M
P
G
C
A
V
T
E
V
E
I
D
G
V
L
H
E
Y
S
T
K
E
G
V
Q
E
D
I
L
E
I
L
L
N
L
K
G
L
A
V
R
V
Q
G
K
D
E
V
I
L
T
L
N
K
S
G
I
G
P
V
T
A
A
D
I
T
H
D
G
D
V
E
I
V
K
P
Q
H
V
I
C
H
L
-
T
D
E
-
N
A
S
I
S
M
R
I
K
V
Q
R
G
R
G
Y
V
P
A
S
T
R
I
H
S
E
E
D
E
R
P
------
I
G
R
L
L
V
D
A
C
Y
S
P
V
E
R
I
A
Y
N
V
E
A
A
R
V
E
Q
R
T
D
L
D
K
L
V
I
E
M
E
T
N
G
T
I
D
P
E
E
A
I
R
R
A
A
T
I
L
A
E
Q
L
E
A
F
V
D
L
R
------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
75.68
45%
-116
- C3 -
4YFX
-
RPOA_ECO24
A:
[20-235]
----------------------------
S
S
T
H
A
K
V
T
L
E
P
L
E
R
G
F
G
H
T
L
G
N
A
L
R
R
I
L
L
S
S
M
P
G
C
A
V
T
E
V
E
I
D
G
V
L
H
E
Y
S
T
K
E
G
V
Q
E
D
I
L
E
I
L
L
N
L
K
G
L
A
V
R
V
Q
G
K
D
E
V
I
L
T
L
N
K
S
G
I
G
P
V
T
A
A
D
I
T
H
D
G
D
V
E
I
V
K
P
Q
H
V
I
C
H
L
-
T
D
E
-
N
A
S
I
S
M
R
I
K
V
Q
R
G
R
G
Y
V
P
A
S
T
R
I
H
S
E
E
D
E
R
P
------
I
G
R
L
L
V
D
A
C
Y
S
P
V
E
R
I
A
Y
N
V
E
A
A
R
V
E
Q
R
T
D
L
D
K
L
V
I
E
M
E
T
N
G
T
I
D
P
E
E
A
I
R
R
A
A
T
I
L
A
E
Q
L
E
A
F
V
D
L
R
------------------------------------------------------------------------------------------------------------
56
Fugue
74.98
40%
-120
- C3 -
1BDF
-
RPOA_ECOLI
A:
[2-232]
---------
Q
G
S
V
T
E
F
L
K
P
R
L
V
D
I
E
Q
V
S
S
T
-
H
A
K
V
T
L
E
P
L
E
R
G
F
G
H
T
L
G
N
A
L
R
A
I
L
L
S
S
M
P
G
C
A
V
T
E
V
E
I
D
G
V
L
H
E
Y
S
T
K
E
G
V
Q
E
D
I
L
E
I
L
L
N
L
K
G
L
A
V
R
V
Q
G
K
D
E
V
I
L
T
L
N
K
S
G
I
G
P
V
T
A
A
D
I
T
H
D
G
D
V
E
I
V
K
P
Q
H
V
I
C
H
L
T
D
-
E
-
N
A
S
I
S
M
R
I
K
V
Q
R
G
R
G
Y
V
P
A
-
S
T
R
I
E
R
P
----------
I
G
R
L
L
V
D
A
C
Y
S
P
V
E
R
I
A
Y
N
V
E
A
A
R
V
E
Q
R
T
D
L
D
K
L
V
I
E
M
E
T
N
G
T
I
D
P
E
E
A
I
R
R
A
A
T
I
L
A
E
Q
L
E
A
F
V
---------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
74.54
45%
-122
- C3 -
4JKR
-
?
A:
[20-232]
----------------------------
S
S
T
H
A
K
V
T
L
E
P
L
E
R
G
F
G
H
T
L
G
N
A
L
R
R
I
L
L
S
S
M
P
G
C
A
V
T
E
V
E
I
D
G
V
L
H
E
Y
S
T
K
E
G
V
Q
E
D
I
L
E
I
L
L
N
L
K
G
L
A
V
R
V
Q
G
K
D
E
V
I
L
T
L
N
K
S
G
I
G
P
V
T
A
A
D
I
T
H
D
G
D
V
E
I
V
K
P
Q
H
V
I
C
H
L
-
T
D
E
-
N
A
S
I
S
M
R
I
K
V
Q
R
G
R
G
Y
V
P
A
S
T
R
I
H
S
E
E
D
E
R
P
------
I
G
R
L
L
V
D
A
C
Y
S
P
V
E
R
I
A
Y
N
V
E
A
A
R
V
E
Q
R
T
D
L
D
K
L
V
I
E
M
E
T
N
G
T
I
D
P
E
E
A
I
R
R
A
A
T
I
L
A
E
Q
L
E
A
F
V
---------------------------------------------------------------------------------------------------------------
66
HHSearch
74.12
40%
-118
- C3 -
1BDF
-
RPOA_ECOLI
A:
[4-232]
-----------
S
V
T
E
F
L
K
P
R
L
V
D
I
-
E
Q
V
S
S
T
H
A
K
V
T
L
E
P
L
E
R
G
F
G
H
T
L
G
N
A
L
R
A
I
L
L
S
S
M
P
G
C
A
V
T
E
V
E
I
D
G
V
L
H
E
Y
S
T
K
E
G
V
Q
E
D
I
L
E
I
L
L
N
L
K
G
L
A
V
R
V
Q
G
K
D
E
V
I
L
T
L
N
K
S
G
I
G
P
V
T
A
A
D
I
T
H
D
G
D
V
E
I
V
K
P
Q
H
V
I
C
H
L
-
T
-
D
E
N
A
S
I
S
M
R
I
K
V
Q
R
G
R
G
Y
V
P
A
-
S
T
R
I
----------
E
R
P
I
G
R
L
L
V
D
A
C
Y
S
P
V
E
R
I
A
Y
N
V
E
A
A
R
V
E
Q
R
T
D
L
D
K
L
V
I
E
M
E
T
N
G
T
I
D
P
E
E
A
I
R
R
A
A
T
I
L
A
E
Q
L
E
A
F
V
---------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
73.64
45%
-117
- C3 -
4S20
-
?
A:
[20-232]
----------------------------
S
S
T
H
A
K
V
T
L
E
P
L
E
R
G
F
G
H
T
L
G
N
A
L
R
R
I
L
L
S
S
M
P
G
C
A
V
T
E
V
E
I
D
G
V
L
H
E
Y
S
T
K
E
G
V
Q
E
D
I
L
E
I
L
L
N
L
K
G
L
A
V
R
V
Q
G
K
D
E
V
I
L
T
L
N
K
S
G
I
G
P
V
T
A
A
D
I
T
H
D
G
D
V
E
I
V
K
P
Q
H
V
I
C
H
L
-
T
D
E
-
N
A
S
I
S
M
R
I
K
V
Q
R
G
R
G
Y
V
P
A
S
T
R
I
H
S
E
E
D
E
R
P
------
I
G
R
L
L
V
D
A
C
Y
S
P
V
E
R
I
A
Y
N
V
E
A
A
R
V
E
Q
R
T
D
L
D
K
L
V
I
E
M
E
T
N
G
T
I
D
P
E
E
A
I
R
R
A
A
T
I
L
A
E
Q
L
E
A
F
V
---------------------------------------------------------------------------------------------------------------
49
PsiBlast_CBE
49.12
65%
-89
- C3 -
3N97
2
RPOA_ECOLI
B:
[5-79]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
P
I
L
L
R
P
V
D
D
L
E
L
T
V
R
S
A
N
C
L
K
A
E
A
I
H
Y
I
G
D
L
V
Q
R
T
E
V
E
L
L
K
T
P
N
L
G
K
K
S
L
T
E
I
K
D
V
L
A
S
R
G
L
S
L
G
M
R
L
E
N
W
P
P
A
-------------
48
PsiBlast_CBE
48.22
65%
-91
- C3 -
3N97
3
C:
[5-78]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
P
I
L
L
R
P
V
D
D
L
E
L
T
V
R
S
A
N
C
L
K
A
E
A
I
H
Y
I
G
D
L
V
Q
R
T
E
V
E
L
L
K
T
P
N
L
G
K
K
S
L
T
E
I
K
D
V
L
A
S
R
G
L
S
L
G
M
R
L
E
N
W
P
P
--------------