@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Wbm0409: (2015-12-01 )
MTLADKPVLSHAVKKLLTNQYIDYVRVIINRNHEDFYRETIDSLHNYYLSEAVHSFQYVTLKSRKKEEWIPVSSTGMKGRVDTKLLSPVYGGKSRQNSVKLGLESLQKINPDFVVIHDACRPFVSNTLINNLARSMINNQHTGVVPAIEVEDTISLVNDDLIESTIPRERLRAIQTPQIFNFKELLSYHRSNKEFTDDSSLMVEHKKRVVVTRGEKINFKLTTKEDINMAKLLLDEPKYRVGTGYDIHRFIKAQGKAKSFIKICGVEIEYDMKIEAHSDGDVAIHAVVDAILGALGCGDIGAHFPPSFPEWKDRNSSHFLDFAAKKAKEKGYSVSNLDITIVCEEPKISPYKVAMKKFISKTLEIDSEFVNVKATTTEKLGSIGRNEGILAHASVLLYKIAPLHN
Atome Classification :
(86 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240-........250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400...
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MTLAD
K
P
V
L
S
H
A
V
K
K
L
L
T
N
Q
Y
I
D
Y
V
R
V
I
INR
N
H
E
D
F
Y
R
E
T
I
D
S
L
H
N
Y
Y
L
S
E
A
V
H
S
F
Q
Y
V
T
LKSRKKEE
W
I
PVSSTGMKGRVD
T
K
L
LSPVYGGKSRQ
N
S
V
K
L
G
L
E
S
L
Q
KINP
D
F
V
V
I
H
D
A
C
R
P
F
V
S
N
T
L
I
N
N
L
A
R
S
M
INNQHTG
V
V
P
A
I
EV
E
D
T
I
S
L
V
N
D
D
L
I
E
STI
P
R
E
R
L
R
AIQTPQIF
N
F
K
E
L
L
S
Y
H
RSNKEFTDD
S
S
L
M
V
E
HK
K
R
V
V
V
TRG
E
K
I
N
F
K
L
TTKED
I
N
M
A
K
L
LLDEPKYRV--GT
G
Y
D
I
H
R
F
I
K
AQGK
A
K
S
F
I
K
I
CG
V
E
I
E
Y
D
M
K
I
E
AHSDG
D
V
A
I
H
A
V
V
D
A
I
L
G
ALGCGDIGAHFPPSFPEWKDRNS
S
H
F
L
D
F
A
A
K
K
A
K
EKGYSVSNL
D
I
T
I
V
CEEPKI
S
P
Y
K
V
A
M
K
K
F
I
S
K
T
L
EIDS
E
F
V
N
V
K
AT
T
T
E
K
L
G
SIGRNE
G
I
L
A
H
A
S
V
L
L
Y
K
IAPLHN
102
HHSearch
89.38
36%
-95
- C8 -
1W55
5
ISPDF_CAMJE
A:
[27-368]
-
R
L
G
N
D
P
L
W
L
Y
A
T
K
N
L
S
S
F
Y
P
F
K
K
I
V
V
T
S
S
N
I
T
--
Y
M
K
K
-
F
-----------------------------------------
T
K
N
Y
E
F
I
E
G
G
D
T
R
A
E
S
L
K
K
A
L
E
L
I
D
---
S
E
F
V
M
V
S
D
V
A
R
V
L
V
S
K
N
L
F
D
R
L
I
E
N
L
D
--
K
A
D
C
I
T
P
A
L
K
V
A
D
T
T
L
F
D
N
-----
E
A
L
Q
R
E
K
I
K
L
I
Q
T
P
Q
I
S
K
T
K
L
L
K
K
A
L
D
Q
N
L
E
F
T
D
D
S
T
A
I
A
A
M
G
G
K
I
W
F
V
E
G
E
E
N
A
R
K
L
T
F
K
E
D
L
K
K
L
D
L
P
T
P
S
F
E
I
F
T
--
G
N
G
F
D
V
H
E
F
G
E
N
-----
R
P
L
L
L
A
G
V
Q
I
H
P
T
M
G
L
K
A
H
S
D
G
D
V
L
A
H
S
L
T
D
A
I
L
G
A
A
G
L
G
D
I
G
E
L
Y
P
D
T
D
M
K
F
K
N
A
N
S
M
E
L
L
K
Q
A
Y
D
K
V
R
E
I
G
F
E
L
I
N
I
D
I
C
V
M
A
Q
S
P
K
L
K
D
F
K
Q
A
M
Q
S
N
I
A
H
T
L
D
L
D
E
F
R
I
N
V
K
A
T
T
T
E
K
L
G
F
I
G
R
K
E
G
M
A
V
L
S
S
V
N
L
K
Y
F
D
W
T
R
-
1
PsiBlast_PDB
85.00
38%
-92
- C8 -
1W55
5
ISPDF_CAMJE
A:
[70-361]
----------------------------------------------------------------------------------------
I
E
G
G
D
T
R
A
E
S
L
K
---
K
A
L
E
L
I
D
S
E
F
V
M
V
S
D
V
A
R
V
L
V
S
K
N
L
F
D
R
L
I
E
N
L
--
D
K
A
D
C
I
T
P
A
L
K
V
A
D
T
T
L
F
D
N
E
A
L
-----
Q
R
E
K
I
K
L
I
Q
T
P
Q
I
S
K
T
K
L
L
K
K
A
L
D
Q
N
L
E
F
T
D
D
S
T
A
I
A
A
M
G
G
K
I
W
F
V
E
G
E
E
N
A
R
K
L
T
F
K
E
D
L
K
--
K
L
D
L
P
T
P
S
F
E
I
F
T
G
N
G
F
D
V
H
E
F
----
G
E
N
R
P
L
L
-
L
A
G
V
Q
I
H
P
T
M
G
L
K
A
H
S
D
G
D
V
L
A
H
S
L
T
D
A
I
L
G
A
A
G
L
G
D
I
G
E
L
Y
P
D
T
D
M
K
F
K
N
A
N
S
M
E
L
L
K
Q
A
Y
D
K
V
R
E
I
G
F
E
L
I
N
I
D
I
C
V
M
A
Q
S
P
K
L
K
D
F
K
Q
A
M
Q
S
N
I
A
H
T
L
D
L
D
E
F
R
I
N
V
K
A
T
T
T
E
K
L
G
F
I
G
R
K
E
G
M
A
V
L
S
S
V
N
L
K
Y
F
D
W
T
R
-
2
PsiBlast_PDB
84.56
38%
-100
- C8 -
1W57
4
ISPDF_CAMJE
A:
[70-361]
----------------------------------------------------------------------------------------
I
E
G
G
D
T
R
A
E
S
L
K
---
K
A
L
E
L
I
D
S
E
F
V
M
V
S
D
V
A
R
V
L
V
S
K
N
L
F
D
R
L
I
E
N
L
--
D
K
A
D
C
I
T
P
A
L
K
V
A
D
T
T
L
F
D
N
E
A
L
-----
Q
R
E
K
I
K
L
I
Q
T
P
Q
I
S
K
T
K
L
L
K
K
A
L
D
Q
N
L
E
F
T
D
D
S
T
A
I
A
A
M
G
G
K
I
W
F
V
E
G
E
E
N
A
R
K
L
T
F
K
E
D
L
K
--
K
L
D
L
P
T
P
S
F
E
I
F
T
G
N
G
F
D
V
H
E
F
----
G
E
N
R
P
L
L
-
L
A
G
V
Q
I
H
P
T
M
G
L
K
A
H
S
D
G
D
V
L
A
H
S
L
T
D
A
I
L
G
A
A
G
L
G
D
I
G
E
L
Y
P
D
T
D
M
K
F
K
N
A
N
S
M
E
L
L
K
Q
A
Y
D
K
V
R
E
I
G
F
E
L
I
N
I
D
I
C
V
M
A
Q
S
P
K
L
K
D
F
K
Q
A
M
Q
S
N
I
A
H
T
L
D
L
D
E
F
R
I
N
V
K
A
T
T
T
E
K
L
G
F
I
G
R
K
E
G
M
A
V
L
S
S
V
N
L
K
Y
F
D
W
T
R
-
24
PsiBlast_CBE
76.17
46%
-124
- C8 -
5B8F
6
ISPF_PSEAE
B:
[9-161]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
I
--
G
H
G
Y
D
V
H
R
F
G
E
G
D
-----
F
I
T
L
G
G
V
R
I
P
H
K
H
G
L
V
A
H
S
D
G
D
V
L
L
H
A
L
S
D
A
L
L
G
A
A
A
L
G
D
I
G
K
H
F
P
D
T
D
P
R
F
K
G
A
D
S
R
A
L
L
R
H
V
V
A
I
V
A
E
K
G
W
K
V
G
N
V
D
A
T
I
V
A
Q
A
P
K
M
A
P
H
I
E
T
M
R
G
L
I
A
E
D
L
G
V
A
V
D
Q
V
N
V
K
A
T
T
T
E
R
L
G
F
T
G
R
E
E
G
I
A
V
H
A
V
A
L
L
M
A
R
-----
6
PsiBlast_PDB
75.77
46%
-125
- C8 -
5B8F
7
ISPF_PSEAE
A:
[9-161]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
I
--
G
H
G
Y
D
V
H
R
F
G
E
G
D
-----
F
I
T
L
G
G
V
R
I
P
H
K
H
G
L
V
A
H
S
D
G
D
V
L
L
H
A
L
S
D
A
L
L
G
A
A
A
L
G
D
I
G
K
H
F
P
D
T
D
P
R
F
K
G
A
D
S
R
A
L
L
R
H
V
V
A
I
V
A
E
K
G
W
K
V
G
N
V
D
A
T
I
V
A
Q
A
P
K
M
A
P
H
I
E
T
M
R
G
L
I
A
E
D
L
G
V
A
V
D
Q
V
N
V
K
A
T
T
T
E
R
L
G
F
T
G
R
E
E
G
I
A
V
H
A
V
A
L
L
M
A
R
-----
97
PsiBlast_CBE
75.48
39%
-123
- C8 -
3F0G
2
ISPF_BURP1
A:
[24-179]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
R
I
--
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
-----
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
D
T
D
P
R
F
K
G
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
E
-----
23
PsiBlast_CBE
74.92
46%
-122
- C8 -
5B8F
6
ISPF_PSEAE
C:
[9-161]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
I
--
G
H
G
Y
D
V
H
R
F
G
E
G
D
-----
F
I
T
L
G
G
V
R
I
P
H
K
H
G
L
V
A
H
S
D
G
D
V
L
L
H
A
L
S
D
A
L
L
G
A
A
A
L
G
D
I
G
K
H
F
P
D
T
D
P
R
F
K
G
A
D
S
R
A
L
L
R
H
V
V
A
I
V
A
E
K
G
W
K
V
G
N
V
D
A
T
I
V
A
Q
A
P
K
M
A
P
H
I
E
T
M
R
G
L
I
A
E
D
L
G
V
A
V
D
Q
V
N
V
K
A
T
T
T
E
R
L
G
F
T
G
R
E
E
G
I
A
V
H
A
V
A
L
L
M
A
R
-----
7
PsiBlast_PDB
73.71
45%
-110
- C8 -
1T0A
4
ISPF_SHEON
A:
[2-158]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
I
R
I
--
G
H
G
F
D
V
H
K
F
----
G
E
P
R
P
L
I
-
L
C
G
V
E
V
P
Y
E
T
G
L
V
A
H
S
D
G
D
V
V
L
H
A
I
S
D
A
I
L
G
A
M
A
L
G
D
I
G
K
H
F
P
D
T
D
A
A
Y
K
G
A
D
S
R
V
L
L
R
H
C
Y
A
L
A
K
A
K
G
F
E
L
G
N
L
D
V
T
I
I
A
Q
A
P
K
M
A
P
H
I
E
D
M
R
Q
V
L
A
A
D
L
N
A
D
V
A
D
I
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
K
E
G
I
A
V
E
A
V
V
L
L
S
R
Q
-----
90
PsiBlast_CBE
72.99
39%
-131
- C8 -
3IEQ
4
ISPF_BURP1
B:
[24-179]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
R
I
--
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
-----
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
---
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
D
T
D
P
R
F
--
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
------
94
PsiBlast_CBE
72.91
39%
-121
- C8 -
3F0G
3
ISPF_BURP1
D:
[24-179]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
R
I
--
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
-----
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
D
T
D
P
R
F
K
G
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
E
-----
98
PsiBlast_CBE
72.77
39%
-121
- C8 -
3F0F
2
ISPF_BURP1
C:
[24-179]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
R
I
--
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
-----
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
---
P
R
F
K
G
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
E
-----
105
HHSearch
72.49
45%
-115
* C8 *
1YQN
4
ISPF_ECOLI
A:
[2-158]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
M
R
I
--
G
H
G
F
D
V
H
A
F
G
G
E
-----
G
P
I
I
I
G
G
V
R
I
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
M
G
L
G
I
A
C
E
A
V
A
L
L
I
K
------
72
PsiBlast_CBE
72.43
39%
-131
- C8 -
3MBM
5
ISPF_BURP1
B:
[24-179]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
R
I
--
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
-----
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
-
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
D
T
D
---
K
G
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
------
88
PsiBlast_CBE
72.29
39%
-124
- C8 -
3IEW
4
ISPF_BURPS
A:
[24-179]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
R
I
--
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
-----
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
D
T
D
P
R
F
K
G
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
E
-----
75
PsiBlast_CBE
72.28
39%
-126
- C8 -
3KE1
3
ISPF_BURP1
B:
[24-179]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
R
I
--
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
-----
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
--
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
---------
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
------
63
PsiBlast_CBE
72.24
39%
-125
- C8 -
3Q8H
3
ISPF_BURPS
B:
[24-179]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
R
I
--
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
-----
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
----
P
R
F
K
G
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
E
-----
70
PsiBlast_CBE
71.87
39%
-124
- C8 -
3P0Z
5
ISPF_BURP1
A:
[24-179]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
R
I
--
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
-----
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
D
T
D
P
R
F
K
G
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
------
62
PsiBlast_CBE
71.76
39%
-124
- C8 -
3Q8H
3
ISPF_BURPS
C:
[24-179]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
R
I
--
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
-----
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
D
T
D
P
R
F
K
G
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
------
61
PsiBlast_CBE
71.76
39%
-125
- C8 -
3QHD
6
ISPF_BURP1
A:
[24-179]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
R
I
--
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
-----
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
D
T
D
P
R
F
K
G
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
E
-----
78
PsiBlast_CBE
71.72
39%
-127
- C8 -
3K2X
3
ISPF_BURP1
B:
[24-179]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
R
I
--
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
-----
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
--
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
D
T
D
P
R
---
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
------
73
PsiBlast_CBE
71.68
39%
-123
- C8 -
3MBM
5
ISPF_BURP1
A:
[24-179]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
R
I
--
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
-----
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
D
T
D
P
R
F
K
G
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
------
91
PsiBlast_CBE
71.58
39%
-124
- C8 -
3IEQ
4
ISPF_BURP1
A:
[24-179]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
R
I
--
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
-----
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
D
T
D
P
R
F
K
G
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
------
96
PsiBlast_CBE
71.57
39%
-124
- C8 -
3F0G
3
ISPF_BURP1
B:
[24-179]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
R
I
--
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
-----
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
--
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
D
T
--
R
F
K
G
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
------
85
PsiBlast_CBE
71.54
39%
-125
- C8 -
3JVH
4
ISPF_BURP1
A:
[24-179]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
R
I
--
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
-----
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
D
T
D
P
R
F
K
G
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
------
82
PsiBlast_CBE
71.48
39%
-125
- C8 -
3K14
5
ISPF_BURP1
A:
[24-179]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
R
I
--
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
-----
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
D
T
D
P
R
F
K
G
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
------
81
PsiBlast_CBE
71.37
39%
-130
- C8 -
3K14
4
ISPF_BURP1
B:
[24-179]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
R
I
--
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
-----
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
---
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
D
T
------
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
------
100
PsiBlast_CBE
71.29
39%
-123
- C8 -
3F0F
2
ISPF_BURP1
A:
[24-179]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
R
I
--
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
-----
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
D
T
D
P
R
F
K
G
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
E
-----
59
PsiBlast_CBE
71.29
39%
-121
- C8 -
3QHD
3
ISPF_BURP1
C:
[24-179]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
R
I
--
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
-----
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
D
T
D
P
R
F
K
G
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
E
-----
87
PsiBlast_CBE
71.18
39%
-129
- C8 -
3IEW
4
ISPF_BURPS
B:
[24-179]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
R
I
--
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
-----
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
---
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
-----
F
K
G
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
------
67
PsiBlast_CBE
71.15
39%
-123
- C8 -
3P10
5
ISPF_BURP1
A:
[24-179]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
R
I
--
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
-----
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
D
T
D
P
R
F
K
G
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
E
-----
60
PsiBlast_CBE
71.14
39%
-125
- C8 -
3QHD
5
ISPF_BURP1
B:
[24-179]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
R
I
--
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
-----
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
--------
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
E
-----
99
PsiBlast_CBE
71.11
39%
-123
- C8 -
3F0F
3
ISPF_BURP1
B:
[24-179]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
R
I
--
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
-----
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
D
T
D
P
R
F
K
G
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
E
-----
89
PsiBlast_CBE
71.10
39%
-128
- C8 -
3IEQ
3
ISPF_BURP1
C:
[24-179]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
R
I
--
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
-----
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
----------
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
------
86
PsiBlast_CBE
71.08
39%
-126
- C8 -
3IEW
4
ISPF_BURPS
C:
[24-179]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
R
I
--
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
-----
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
----------
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
E
-----
66
PsiBlast_CBE
71.08
39%
-127
- C8 -
3P10
3
ISPF_BURP1
B:
[24-179]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
R
I
--
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
-----
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
D
T
D
P
R
F
K
G
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
E
-----
104
HHSearch
71.04
47%
-118
- C8 -
2PMP
4
ISPF_ARATH
A:
[2-159]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
P
F
R
I
--
G
H
G
F
D
L
H
R
L
E
P
G
-----
Y
P
L
I
I
G
G
I
V
I
P
H
D
R
G
C
E
A
H
S
D
G
D
V
L
L
H
C
V
V
D
A
I
L
G
A
L
G
L
P
D
I
G
Q
I
F
P
D
S
D
P
K
W
K
G
A
A
S
S
V
F
I
K
E
A
V
R
L
M
D
E
A
G
Y
E
I
G
N
L
D
A
T
L
I
L
Q
R
P
K
I
S
P
H
K
E
T
I
R
S
N
L
S
K
L
L
G
A
D
P
S
V
V
N
L
K
A
K
T
H
E
K
V
D
S
L
G
E
N
R
S
I
A
A
H
T
V
I
L
L
M
K
K
-----
93
PsiBlast_CBE
71.01
39%
-121
- C8 -
3F0G
3
ISPF_BURP1
E:
[24-179]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
R
I
--
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
-----
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
-----------
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
E
-----
45
PsiBlast_CBE
70.75
42%
-92
- C8 -
3ERN
3
ISPF_ECOLI
C:
[6-162]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
M
R
I
--
G
H
G
F
D
V
H
A
F
G
G
E
G
P
I
I
I
G
G
V
R
I
-----
P
Y
E
------
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
I
K
------
77
PsiBlast_CBE
70.74
39%
-126
- C8 -
3K2X
3
ISPF_BURP1
C:
[24-179]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
R
I
--
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
-----
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
--
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
----------
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
E
-----
84
PsiBlast_CBE
70.73
39%
-125
- C8 -
3JVH
4
ISPF_BURP1
B:
[24-179]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
R
I
--
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
-----
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
---------
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
------
68
PsiBlast_CBE
70.59
39%
-126
- C8 -
3P0Z
3
ISPF_BURP1
C:
[24-179]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
R
I
--
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
-----
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
------
F
K
G
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
E
-----
92
PsiBlast_CBE
70.48
39%
-127
- C8 -
3F0G
3
ISPF_BURP1
F:
[24-179]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
R
I
--
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
-----
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
----------
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
------
76
PsiBlast_CBE
70.45
39%
-123
- C8 -
3KE1
3
ISPF_BURP1
A:
[24-179]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
R
I
--
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
-----
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
---------
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
E
-----
69
PsiBlast_CBE
70.43
39%
-127
- C8 -
3P0Z
4
ISPF_BURP1
B:
[24-179]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
R
I
--
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
-----
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
--------
G
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
E
-----
79
PsiBlast_CBE
70.28
39%
-123
- C8 -
3K2X
5
ISPF_BURP1
A:
[24-179]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
R
I
--
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
-----
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
D
----
F
K
G
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
------
64
PsiBlast_CBE
70.26
39%
-126
- C8 -
3Q8H
5
ISPF_BURPS
A:
[24-179]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
R
I
--
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
-----
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
--------
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
E
-----
71
PsiBlast_CBE
70.13
39%
-118
- C8 -
3MBM
5
ISPF_BURP1
C:
[24-179]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
R
I
--
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
-----
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
D
-------
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
------
65
PsiBlast_CBE
70.08
39%
-123
- C8 -
3P10
3
ISPF_BURP1
C:
[24-179]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
R
I
--
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
-----
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
------
F
K
G
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
E
-----
5
PsiBlast_PDB
69.79
46%
-117
- C8 -
2PMP
4
ISPF_ARATH
A:
[4-159]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
R
I
--
G
H
G
F
D
L
H
R
L
-----
E
P
G
Y
P
L
I
I
G
G
I
V
I
P
H
D
R
G
C
E
A
H
S
D
G
D
V
L
L
H
C
V
V
D
A
I
L
G
A
L
G
L
P
D
I
G
Q
I
F
P
D
S
D
P
K
W
K
G
A
A
S
S
V
F
I
K
E
A
V
R
L
M
D
E
A
G
Y
E
I
G
N
L
D
A
T
L
I
L
Q
R
P
K
I
S
P
H
K
E
T
I
R
S
N
L
S
K
L
L
G
A
D
P
S
V
V
N
L
K
A
K
T
H
E
K
V
D
S
L
G
E
N
R
S
I
A
A
H
T
V
I
L
L
M
K
K
-----
42
PsiBlast_CBE
69.74
42%
-97
- C8 -
3ERN
2
ISPF_ECOLI
F:
[6-162]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
M
R
I
--
G
H
G
F
D
V
H
A
F
G
---
P
I
I
I
G
G
V
R
I
-----
P
Y
------
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
I
K
------
83
PsiBlast_CBE
69.70
39%
-119
- C8 -
3JVH
4
ISPF_BURP1
C:
[24-179]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
R
I
--
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
-----
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
------
F
K
G
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
E
-----
74
PsiBlast_CBE
69.67
39%
-124
- C8 -
3KE1
3
ISPF_BURP1
C:
[24-179]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
R
I
--
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
-----
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
--
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
----------
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
E
-----
80
PsiBlast_CBE
68.52
39%
-122
- C8 -
3K14
4
ISPF_BURP1
C:
[24-179]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
R
I
--
G
Q
G
Y
D
V
H
Q
L
V
P
G
R
-----
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
----------
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
------
47
PsiBlast_CBE
67.33
42%
-90
- C8 -
3ELC
4
ISPF_ECOLI
C:
[6-162]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
M
R
I
--
G
H
G
F
D
V
H
A
F
G
G
E
G
P
I
I
I
G
G
V
R
I
-----
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
I
K
------
33
PsiBlast_CBE
67.17
42%
-91
- C8 -
1H48
8
ISPF_ECOLI
E:
[2-158]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
M
R
I
--
G
H
G
F
D
V
H
A
F
G
G
E
G
P
I
I
I
G
G
V
R
I
-----
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
I
K
------
16
PsiBlast_PDB
66.66
42%
-87
- C8 -
3ERN
4
ISPF_ECOLI
A:
[6-162]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
M
R
I
--
G
H
G
F
D
V
H
A
F
G
G
E
G
P
I
I
I
G
G
V
R
I
-----
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
I
K
------
11
PsiBlast_PDB
66.45
43%
-89
- C8 -
3T80
10
ISPF_SALTY
A:
[5-159]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
I
--
G
H
G
F
D
V
H
A
F
G
G
E
G
P
I
I
I
G
G
V
R
I
-----
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
E
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
M
K
------
48
PsiBlast_CBE
66.40
42%
-92
- C8 -
3ELC
4
ISPF_ECOLI
B:
[6-162]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
M
R
I
--
G
H
G
F
D
V
H
A
F
G
G
E
G
P
I
I
I
G
G
V
R
I
-----
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
I
K
------
38
PsiBlast_CBE
66.34
42%
-89
- C8 -
1H47
4
ISPF_ECOLI
E:
[2-158]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
M
R
I
--
G
H
G
F
D
V
H
A
F
G
G
E
G
P
I
I
I
G
G
V
R
I
-----
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
I
K
------
37
PsiBlast_CBE
66.28
42%
-89
- C8 -
1H47
4
ISPF_ECOLI
F:
[2-158]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
M
R
I
--
G
H
G
F
D
V
H
A
F
G
G
E
G
P
I
I
I
G
G
V
R
I
-----
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
I
K
------
46
PsiBlast_CBE
65.91
42%
-90
- C8 -
3ERN
5
ISPF_ECOLI
B:
[6-162]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
M
R
I
--
G
H
G
F
D
V
H
A
F
G
G
E
G
P
I
I
I
G
G
V
R
I
-----
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
I
K
------
41
PsiBlast_CBE
65.79
42%
-88
- C8 -
1H47
5
ISPF_ECOLI
B:
[2-158]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
M
R
I
--
G
H
G
F
D
V
H
A
F
G
G
E
G
P
I
I
I
G
G
V
R
I
-----
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
I
K
------
51
PsiBlast_CBE
65.75
43%
-85
- C8 -
2AMT
4
ISPF_ECOLI
D:
[2-156]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
I
--
G
H
G
F
D
V
H
A
F
G
G
E
G
P
I
I
I
G
G
V
R
I
-----
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
I
K
------
35
PsiBlast_CBE
65.64
42%
-84
- C8 -
1H48
6
ISPF_ECOLI
C:
[2-158]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
M
R
I
--
G
H
G
F
D
V
H
A
F
G
G
E
G
P
I
I
I
G
G
V
R
I
-----
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
I
K
A
-----
40
PsiBlast_CBE
65.60
42%
-90
- C8 -
1H47
4
ISPF_ECOLI
C:
[2-158]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
M
R
I
--
G
H
G
F
D
V
H
A
F
G
G
E
G
P
I
I
I
G
G
V
R
I
-----
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
I
K
------
52
PsiBlast_CBE
65.21
43%
-86
- C8 -
2AMT
5
ISPF_ECOLI
C:
[2-156]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
I
--
G
H
G
F
D
V
H
A
F
G
G
E
G
P
I
I
I
G
G
V
R
I
-----
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
I
K
------
36
PsiBlast_CBE
65.07
42%
-88
- C8 -
1H48
6
ISPF_ECOLI
B:
[2-158]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
M
R
I
--
G
H
G
F
D
V
H
A
F
G
G
E
G
P
I
I
I
G
G
V
R
I
-----
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
I
K
------
13
PsiBlast_PDB
65.06
42%
-90
- C8 -
1H48
6
ISPF_ECOLI
A:
[2-158]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
M
R
I
--
G
H
G
F
D
V
H
A
F
G
G
E
G
P
I
I
I
G
G
V
R
I
-----
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
I
K
------
30
PsiBlast_CBE
64.96
43%
-90
- C8 -
3GHZ
4
ISPF_SALTY
C:
[5-159]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
I
--
G
H
G
F
D
V
H
A
F
G
G
E
G
P
I
I
I
G
G
V
R
I
-----
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
E
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
M
K
------
12
PsiBlast_PDB
64.79
42%
-89
- C8 -
1H47
4
ISPF_ECOLI
A:
[2-158]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
M
R
I
--
G
H
G
F
D
V
H
A
F
G
G
E
G
P
I
I
I
G
G
V
R
I
-----
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
I
K
------
34
PsiBlast_CBE
64.75
42%
-91
- C8 -
1H48
8
ISPF_ECOLI
D:
[2-158]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
M
R
I
--
G
H
G
F
D
V
H
A
F
G
G
E
G
P
I
I
I
G
G
V
R
I
-----
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
I
K
------
14
PsiBlast_PDB
64.72
42%
-88
- C8 -
3ELC
4
ISPF_ECOLI
A:
[6-162]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
M
R
I
--
G
H
G
F
D
V
H
A
F
G
G
E
G
P
I
I
I
G
G
V
R
I
-----
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
I
K
------
108
HHSearch
64.60
31%
-114
- C8 -
2UZH
7
?
A:
[5-159]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
P
R
V
--
G
L
G
T
D
V
H
P
I
E
A
G
-----
R
P
C
R
L
L
C
L
E
F
D
D
A
D
G
C
A
--
S
D
G
D
V
A
A
H
A
L
C
D
A
L
L
S
A
A
G
L
G
D
L
G
T
I
F
G
T
D
R
P
Q
W
R
G
A
S
G
A
D
M
I
R
H
V
R
G
L
V
E
N
A
G
F
V
I
G
N
A
T
V
Q
V
I
G
N
R
P
K
V
G
P
R
R
E
E
A
Q
Q
V
L
S
E
L
V
G
A
P
---
V
S
V
S
A
T
T
T
D
G
L
G
L
T
G
R
G
E
G
L
A
A
I
A
T
A
L
V
A
A
E
-----
10
PsiBlast_PDB
64.53
43%
-91
- C8 -
3GHZ
5
ISPF_SALTY
A:
[5-159]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
I
--
G
H
G
F
D
V
H
A
F
G
G
E
G
P
I
I
I
G
G
V
R
I
-----
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
E
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
M
K
------
29
PsiBlast_CBE
64.31
43%
-88
- C8 -
3T80
12
ISPF_SALTY
B:
[5-159]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
I
--
G
H
G
F
D
V
H
A
F
G
G
E
G
P
I
I
I
G
G
V
R
I
-----
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
----------
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
E
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
M
K
------
50
PsiBlast_CBE
64.27
43%
-92
- C8 -
2AMT
4
ISPF_ECOLI
E:
[2-156]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
I
--
G
H
G
F
D
V
H
A
F
G
G
E
G
P
I
I
I
G
G
V
R
I
-----
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
I
K
------
58
PsiBlast_CBE
64.12
43%
-89
- C8 -
1U3L
3
ISPF_ECOLI
A:
[2-155]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
I
--
G
H
G
F
D
V
H
A
F
G
G
E
G
P
I
I
I
G
G
V
R
I
-----
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
I
-------
39
PsiBlast_CBE
64.10
42%
-87
- C8 -
1H47
4
ISPF_ECOLI
D:
[2-158]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
M
R
I
--
G
H
G
F
D
V
H
A
F
G
G
E
G
P
I
I
I
G
G
V
R
I
-----
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
I
K
------
44
PsiBlast_CBE
64.03
42%
-89
- C8 -
3ERN
4
ISPF_ECOLI
D:
[6-162]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
M
R
I
--
G
H
G
F
D
V
H
A
F
G
G
E
G
P
I
I
I
G
G
V
R
I
-----
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
I
K
------
49
PsiBlast_CBE
64.01
43%
-88
- C8 -
2AMT
4
ISPF_ECOLI
F:
[2-156]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
I
--
G
H
G
F
D
V
H
A
F
G
G
E
G
P
I
I
I
G
G
V
R
I
-----
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
I
K
------
53
PsiBlast_CBE
64.00
43%
-92
- C8 -
2AMT
4
ISPF_ECOLI
B:
[2-156]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
I
--
G
H
G
F
D
V
H
A
F
G
G
E
G
P
I
I
I
G
G
V
R
I
-----
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
I
K
------
32
PsiBlast_CBE
63.94
42%
-89
- C8 -
1H48
8
ISPF_ECOLI
F:
[2-158]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
M
R
I
--
G
H
G
F
D
V
H
A
F
G
G
E
G
P
I
I
I
G
G
V
R
I
-----
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
I
K
A
-----
56
PsiBlast_CBE
63.54
43%
-87
- C8 -
1U40
2
ISPF_ECOLI
A:
[2-155]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
I
--
G
H
G
F
D
V
H
A
F
G
G
E
G
P
I
I
I
G
G
V
R
I
-----
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
I
-------
55
PsiBlast_CBE
63.23
43%
-86
- C8 -
1U43
1
ISPF_ECOLI
A:
[2-155]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
I
--
G
H
G
F
D
V
H
A
F
G
G
E
G
P
I
I
I
G
G
V
R
I
-----
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
I
-------
28
PsiBlast_CBE
63.03
43%
-91
- C8 -
3T80
9
ISPF_SALTY
C:
[5-159]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
I
--
G
H
G
F
D
V
H
A
F
G
G
E
G
P
I
I
I
G
G
V
R
I
-----
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
------
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
E
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
M
K
------
54
PsiBlast_CBE
61.25
43%
-88
- C8 -
2AMT
4
ISPF_ECOLI
A:
[2-156]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
I
--
G
H
G
F
D
V
H
A
F
G
G
E
G
P
I
I
I
G
G
V
R
I
-----
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
I
K
------