@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Wbm0446: (2015-12-01 )
MTQTWNLLQAGQERNYKVAYINARIIDPETKLDIEGSLLTEGSKIIDFGESLFSNGVPSGVDETINCEGLVLMPGLVDIHVHFREPGQEHKETIYTGSKSAAAGGVTTVVCQPNTTPAIDSVILAKYLKYRALETSHVNIEFYAKITTSEEKLTEVALLKEAGAVGFTDDGIPVMNPMIMRQALLYSSMLNVPIAQHAEDLNLSAGGAINEGKISEALGVKGILSASESVMVSRDILLMKDIENVHYHILHISSKDSLDAVKRAKDLGLNVTCEVTPHHFTLTEDIVKQHGAIAKMNPPLRTEEDRLAMVEGLKTGVIDCIATDHAPHDRSSKDLPLESAAFGIVGLETMLPLSLELYHSGQIDLFDILAKLTYKPADIIHVPRGRVQKNFVADLTLVDLNYEWEIKIDSFASKSKNSPFGGRKVKGRVVRTIVSGKTVYSQK
Atome Classification :
(20 SA)
.........10........20........30........40....-....50....---------------....60..----------......70........80.....--...90........100.......110--.-.....-.120.......130.--......140......---.--150.--........160.....--------.---.170------...-....180.......190.----....--...200-.....---....210..-----.....220...-------....230....-----...240--...-......250.......260.......270.......280......------.290.......300......-.310.......320.......330...---....340----.......350-...-.-.-..360.......370.......--380--.--......390.......400.......410.......420.......430.......440.----------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MTQ
T
W
N
L
L
QAGQER
N
Y
K
V
A
Y
I
N
A
R
I
IDPE
T
K
L
D
IEGSLLTEG
S
K
I
-
I
D
F
G
E
S
L
F
SN---------------GVPSGVDE----------TINCE
G
L
V
LMP
G
L
V
D
I
H
V
H
FREP--
G
Q
E
H
K
E
T
IYTGSKSAAAGG
V
T
T
V
V
CQ--P-NTTP
A
-
I
D
S
V
I
L
A
K
Y
L
K
Y
RAL--E
T
S
H
V
N
I
E
F
Y
A
K
I
TT---
S
--
E
--
E
--
K
L
T
E
V
A
L
L
K
EAGAVGF--------T---DDGI------PVM-
N
P
M
I
M
R
Q
A
L
L
Y
S
S
ML-NV----
P
I
A
Q
--
H
A
E
D---LNLSA---GGAINEG
K
I
-----
S
E
A
LGV
K
G
I
LS-------ASE
S
V
M
VSR
D
I
-----
L
L
M
K
----DIE-N
V
H
Y
H
I
L
H
ISSKD
S
L
D
A
V
K
R
A
K
DLG
L
N
V
T
C
E
VTPH
H
F
T
L
T
E
D
I
V
K
------QHGAIAKMNPPLRT
E
E
D
R
L
A
-
M
V
E
G
L
K
T
G
V
I
D
C
IATDHAPHDRSSKDL---PLESAAF----GIV
G
L
E
TML
P
-
L
S
L
-
E
-
L
-YHSGQ
I
D
L
F
D
I
L
A
K
LTYKPA
D
I
--
I
HV--P--RGR
V
Q
KNFV
A
D
L
T
L
V
DL
N
Y
E
W
E
I
K
I
DSFASKSKNSPFGGRKVKG
R
V
V
R
T
I
VSGKTVYSQK----------------------------------------
4
PsiBlast_PDB
92.49
42%
-66
- C2 -
4BJH
6
PYRC_AQUAE
A:
[37-454]
----------------
K
L
I
V
K
N
G
Y
V
I
D
P
S
Q
N
L
E
G
E
F
D
I
L
V
E
N
G
K
I
-
K
K
I
D
K
N
I
L
------------------
V
P
E
A
--
E
----------
I
I
D
A
K
G
L
I
V
C
P
G
F
I
D
I
H
V
H
L
R
D
P
--
G
Q
T
Y
K
E
D
I
E
S
G
S
R
C
A
V
A
G
G
F
T
T
I
V
C
M
--
P
-
N
T
N
P
P
-
I
D
N
T
T
V
V
N
Y
I
L
Q
K
S
K
--
S
V
G
L
C
R
V
L
P
T
G
T
I
T
K
---
G
--
R
--
K
GK
E
I
A
D
F
Y
S
L
K
E
A
G
C
V
A
F
--------
T
---
D
D
G
S
------
P
V
M
-
D
S
S
V
M
R
K
A
L
E
L
A
S
Q
L
-
G
V
----
P
I
M
D
--
A
C
E
D
---
D
K
L
-
A
---
Y
G
V
I
N
E
G
E
V
-----
S
A
L
L
G
L
S
S
R
A
P
-------
E
A
E
E
I
Q
I
A
R
D
G
-----
I
L
A
Q
----
R
T
G
-
G
-
H
V
H
I
Q
A
V
S
T
K
L
S
L
E
I
I
E
F
F
K
E
K
G
V
K
I
T
C
E
V
N
P
N
H
L
L
F
T
E
R
E
V
L
------
N
S
G
A
N
A
R
V
N
P
P
L
R
K
K
E
D
R
L
A
-
L
I
E
G
V
K
R
G
I
I
D
C
F
A
T
D
H
A
P
H
Q
T
F
E
K
E
L
----
V
E
F
A
M
P
----
G
I
I
G
L
Q
T
A
L
P
-
S
A
L
-
E
-
L
-
Y
R
K
G
I
I
S
L
K
K
L
I
E
M
F
T
I
N
P
A
R
I
--
I
G
V
--
D
--
L
G
T
L
K
L
G
S
P
A
D
I
T
I
F
D
P
N
K
E
W
I
L
N
E
E
T
N
L
S
K
S
R
N
T
P
L
W
G
K
V
L
K
G
K
V
I
Y
T
I
K
D
G
K
M
V
Y
K
D
-----------------------------------------
100
HHSearch
91.56
43%
-74
- C2 -
1XRT
1
PYRC_AQUAE
A:
[46-467]
--------------
M
L
K
L
I
V
K
N
G
Y
V
I
D
P
S
Q
N
L
E
G
E
F
D
I
L
V
E
N
G
K
I
-
K
K
I
D
K
N
I
L
V
--------------------
P
E
A
E
----------
I
I
D
A
K
G
L
I
V
C
P
G
F
I
D
I
H
V
H
L
R
D
P
--
G
Q
T
Y
K
E
D
I
E
S
G
S
R
C
A
V
A
G
G
F
T
T
I
V
C
M
--
P
-
N
T
N
P
P
-
I
D
N
T
T
V
V
N
Y
I
L
Q
K
S
K
--
S
V
G
L
C
R
V
L
P
T
G
T
I
T
K
---
G
RK
G
--
K
--
E
I
A
D
F
Y
S
L
K
E
A
G
C
V
A
F
--------
T
---
D
D
G
S
------
P
V
M
-
D
S
S
V
M
R
K
A
L
E
L
A
S
Q
L
-
G
V
----
P
I
M
D
--
H
C
E
D
---
D
K
L
A
Y
------------------------------------
A
E
E
I
Q
I
A
R
D
G
-----
I
L
A
Q
----
R
-
T
-
G
G
H
V
H
I
Q
H
V
S
T
K
L
S
L
E
I
I
E
F
F
K
E
K
G
V
K
I
T
C
E
V
N
P
N
H
L
L
----------------------------
E
D
R
L
A
-
L
I
E
G
V
K
R
G
I
I
D
C
F
A
T
D
H
A
P
H
Q
T
-------------------
G
I
I
G
L
Q
T
A
L
P
-
S
A
L
-
E
-
L
-
Y
R
K
G
I
I
S
L
K
K
L
I
E
M
F
T
I
N
P
A
R
I
--
I
G
V
--
D
--
L
G
T
L
K
L
G
S
P
A
D
I
T
I
F
D
P
N
K
E
W
I
L
N
E
E
T
N
L
S
K
S
R
N
T
P
L
W
G
K
V
L
K
G
K
V
I
Y
T
I
K
D
G
K
M
V
Y
K
D
-----------------------------------------
5
PsiBlast_PDB
91.54
42%
-67
- C2 -
3MPG
2
PYRC_BACAN
A:
[5-424]
-------------------
F
K
N
G
R
Y
M
N
E
E
G
K
I
-
V
A
T
D
L
L
V
Q
D
G
K
I
-
A
K
V
A
E
N
I
T
A
D
---------------
N
A
-----
E
----------
V
I
D
V
N
G
K
L
I
A
P
G
L
V
D
V
H
V
H
L
R
E
P
--
G
G
E
H
K
E
T
I
E
T
G
T
L
A
A
A
K
G
G
F
T
T
I
C
A
M
--
P
-
N
T
R
P
V
-
P
D
C
R
E
H
M
E
D
L
Q
N
R
I
K
--
E
K
A
H
V
N
V
L
P
Y
G
A
I
T
V
---
R
--
Q
AG
S
--
E
M
T
D
F
E
T
L
K
E
L
G
A
F
A
F
--------
T
---
D
D
G
V
------
G
V
Q
-
D
A
S
M
M
L
A
A
M
K
R
A
A
K
L
-
N
M
----
A
V
V
A
--
H
C
E
E
---
N
T
L
I
N
---
K
G
C
V
H
E
G
K
F
-----
S
E
K
H
G
L
N
G
I
P
S
-------
V
C
E
S
V
H
I
A
R
D
I
-----
L
L
A
-----
E
A
A
-
D
C
H
Y
H
V
C
H
V
S
T
K
G
S
V
R
V
I
R
D
A
K
R
A
G
I
K
V
T
A
E
V
T
P
H
H
L
V
L
C
E
D
D
I
P
------
S
A
D
P
N
F
K
M
N
P
P
L
R
G
K
E
D
H
E
A
-
L
I
E
G
L
L
D
G
T
I
D
M
I
A
T
D
H
A
P
H
T
A
E
E
K
A
Q
---
G
I
E
R
A
P
F
----
G
I
T
G
F
E
T
A
F
P
L
L
Y
T
-
N
-
L
-
V
K
K
G
I
I
T
L
E
Q
L
I
Q
F
L
T
E
K
P
A
D
T
--
F
G
L
--
E
--
A
G
R
L
K
E
G
R
T
A
D
I
T
I
I
D
L
E
Q
E
E
E
I
D
P
T
T
F
L
S
K
G
K
N
T
P
F
A
G
W
K
C
Q
G
W
P
V
M
T
I
V
G
G
K
I
A
W
Q
K
E
----------------------------------------
90
HHSearch
91.43
43%
-64
* C2 *
3MPG
2
PYRC_BACAN
A:
[1-424]
---------------
M
N
Y
L
F
K
N
G
R
Y
M
N
E
E
G
-
K
I
V
A
T
D
L
L
V
Q
D
G
K
I
-
A
K
V
A
E
N
I
T
A
--------------------
D
N
A
E
----------
V
I
D
V
N
G
K
L
I
A
P
G
L
V
D
V
H
V
H
L
R
E
P
--
G
G
E
H
K
E
T
I
E
T
G
T
L
A
A
A
K
G
G
F
T
T
I
C
A
M
--
P
-
N
T
R
P
V
-
P
D
C
R
E
H
M
E
D
L
Q
N
R
I
K
--
E
K
A
H
V
N
V
L
P
Y
G
A
I
T
V
---
R
QA
G
--
S
--
E
M
T
D
F
E
T
L
K
E
L
G
A
F
A
F
--------
T
---
D
D
G
V
------
G
V
Q
-
D
A
S
M
M
L
A
A
M
K
R
A
A
K
L
-
N
M
----
A
V
V
A
--
H
C
E
E
---
N
T
L
I
N
---
K
G
C
V
H
E
G
K
F
-----
S
E
K
H
G
L
N
G
I
P
S
-------
V
C
E
S
V
H
I
A
R
D
I
-----
L
L
A
E
----
A
-
A
-
D
C
H
Y
H
V
C
H
V
S
T
K
G
S
V
R
V
I
R
D
A
K
R
A
G
I
K
V
T
A
E
V
T
P
H
H
L
V
L
C
E
D
D
I
P
------
S
A
D
P
N
F
K
M
N
P
P
L
R
G
K
E
D
H
E
A
-
L
I
E
G
L
L
D
G
T
I
D
M
I
A
T
D
H
A
P
H
T
A
E
E
K
A
Q
---
G
I
E
R
A
P
F
----
G
I
T
G
F
E
T
A
F
P
-
L
L
Y
-
T
N
L
-
V
K
K
G
I
I
T
L
E
Q
L
I
Q
F
L
T
E
K
P
A
D
T
--
F
G
L
--
E
--
A
G
R
L
K
E
G
R
T
A
D
I
T
I
I
D
L
E
Q
E
E
E
I
D
P
T
T
F
L
S
K
G
K
N
T
P
F
A
G
W
K
C
Q
G
W
P
V
M
T
I
V
G
G
K
I
A
W
Q
K
E
----------------------------------------
22
PsiBlast_CBE
91.12
42%
-68
- C2 -
3MPG
2
PYRC_BACAN
B:
[5-424]
-------------------
F
K
N
G
R
Y
M
N
E
E
G
K
I
-
V
A
T
D
L
L
V
Q
D
G
K
I
-
A
K
V
A
E
N
I
T
A
D
---------------
N
A
-----
E
----------
V
I
D
V
N
G
K
L
I
A
P
G
L
V
D
V
H
V
H
L
R
E
P
--
G
G
E
H
K
E
T
I
E
T
G
T
L
A
A
A
K
G
G
F
T
T
I
C
A
M
--
P
-
N
T
R
P
V
-
P
D
C
R
E
H
M
E
D
L
Q
N
R
I
K
--
E
K
A
H
V
N
V
L
P
Y
G
A
I
T
V
---
R
--
Q
AG
S
--
E
M
T
D
F
E
T
L
K
E
L
G
A
F
A
F
--------
T
---
D
D
G
V
------
G
V
Q
-
D
A
S
M
M
L
A
A
M
K
R
A
A
K
L
-
N
M
----
A
V
V
A
--
H
C
E
E
---
N
T
L
I
N
---
K
G
C
V
H
E
G
K
F
-----
S
E
K
H
G
L
N
G
I
P
S
-------
V
C
E
S
V
H
I
A
R
D
I
-----
L
L
A
-----
E
A
A
-
D
C
H
Y
H
V
C
H
V
S
T
K
G
S
V
R
V
I
R
D
A
K
R
A
G
I
K
V
T
A
E
V
T
P
H
H
L
V
L
C
E
D
D
I
P
------
S
A
D
P
N
F
K
M
N
P
P
L
R
G
K
E
D
H
E
A
-
L
I
E
G
L
L
D
G
T
I
D
M
I
A
T
D
H
A
P
H
T
A
E
E
K
A
Q
---
G
I
E
R
A
P
F
----
G
I
T
G
F
E
T
A
F
P
L
L
Y
T
-
N
-
L
-
V
K
K
G
I
I
T
L
E
Q
L
I
Q
F
L
T
E
K
P
A
D
T
--
F
G
L
--
E
--
A
G
R
L
K
E
G
R
T
A
D
I
T
I
I
D
L
E
Q
E
E
E
I
D
P
T
T
F
L
S
K
G
K
N
T
P
F
A
G
W
K
C
Q
G
W
P
V
M
T
I
V
G
G
K
I
A
W
Q
K
E
----------------------------------------
21
PsiBlast_CBE
91.12
42%
-78
- C2 -
1XRT
1
PYRC_AQUAE
B:
[48-465]
----------------
K
L
I
V
K
N
G
Y
V
I
D
P
S
Q
N
L
E
G
E
F
D
I
L
V
E
N
G
K
I
-
K
K
I
D
K
N
I
L
------------------
V
P
E
A
--
E
----------
I
I
D
A
K
G
L
I
V
C
P
G
F
I
D
I
H
V
H
L
R
D
P
--
G
Q
T
Y
K
E
D
I
E
S
G
S
R
C
A
V
A
G
G
F
T
T
I
V
C
M
--
P
-
N
T
N
P
P
-
I
D
N
T
T
V
V
N
Y
I
L
Q
K
S
K
--
S
V
G
L
C
R
V
L
P
T
G
T
I
T
K
---
G
--
R
--
K
GK
E
I
A
D
F
Y
S
L
K
E
A
G
C
V
A
F
--------
T
---
D
D
G
S
------
P
V
M
-
D
S
S
V
M
R
K
A
L
E
L
A
S
Q
L
-
G
V
----
P
I
M
D
--
H
C
E
D
---
D
K
L
-
A
-----------------------------------
E
A
E
E
I
Q
I
A
R
D
G
-----
I
L
A
Q
----
R
T
G
-
G
-
H
V
H
I
Q
H
V
S
T
K
L
S
L
E
I
I
E
F
F
K
E
K
G
V
K
I
T
C
E
V
N
P
N
H
L
L
------------------------------
R
L
A
-
L
I
E
G
V
K
R
G
I
I
D
C
F
A
T
D
H
A
P
H
Q
T
--------------
P
----
G
I
I
G
L
Q
T
A
L
P
-
S
A
L
-
E
-
L
-
Y
R
K
G
I
I
S
L
K
K
L
I
E
M
F
T
I
N
P
A
R
I
--
I
G
V
--
D
--
L
G
T
L
K
L
G
S
P
A
D
I
T
I
F
D
P
N
K
E
W
I
L
N
E
E
T
N
L
S
K
S
R
N
T
P
L
W
G
K
V
L
K
G
K
V
I
Y
T
I
K
D
G
K
M
V
Y
K
D
-----------------------------------------
2
PsiBlast_PDB
90.85
42%
-76
- C2 -
1XRT
1
PYRC_AQUAE
A:
[48-465]
----------------
K
L
I
V
K
N
G
Y
V
I
D
P
S
Q
N
L
E
G
E
F
D
I
L
V
E
N
G
K
I
-
K
K
I
D
K
N
I
L
------------------
V
P
E
A
--
E
----------
I
I
D
A
K
G
L
I
V
C
P
G
F
I
D
I
H
V
H
L
R
D
P
--
G
Q
T
Y
K
E
D
I
E
S
G
S
R
C
A
V
A
G
G
F
T
T
I
V
C
M
--
P
-
N
T
N
P
P
-
I
D
N
T
T
V
V
N
Y
I
L
Q
K
S
K
--
S
V
G
L
C
R
V
L
P
T
G
T
I
T
K
---
G
--
R
--
K
GK
E
I
A
D
F
Y
S
L
K
E
A
G
C
V
A
F
--------
T
---
D
D
G
S
------
P
V
M
-
D
S
S
V
M
R
K
A
L
E
L
A
S
Q
L
-
G
V
----
P
I
M
D
--
H
C
E
D
---
D
K
L
-
A
---
Y
--------------------------------
A
E
E
I
Q
I
A
R
D
G
-----
I
L
A
Q
----
R
T
G
-
G
-
H
V
H
I
Q
H
V
S
T
K
L
S
L
E
I
I
E
F
F
K
E
K
G
V
K
I
T
C
E
V
N
P
N
H
L
L
----------------------------
E
D
R
L
A
-
L
I
E
G
V
K
R
G
I
I
D
C
F
A
T
D
H
A
P
H
Q
T
-------------------
G
I
I
G
L
Q
T
A
L
P
-
S
A
L
-
E
-
L
-
Y
R
K
G
I
I
S
L
K
K
L
I
E
M
F
T
I
N
P
A
R
I
--
I
G
V
--
D
--
L
G
T
L
K
L
G
S
P
A
D
I
T
I
F
D
P
N
K
E
W
I
L
N
E
E
T
N
L
S
K
S
R
N
T
P
L
W
G
K
V
L
K
G
K
V
I
Y
T
I
K
D
G
K
M
V
Y
K
D
-----------------------------------------
1
PsiBlast_PDB
90.61
42%
-86
- C2 -
1XRF
2
PYRC_AQUAE
A:
[48-465]
----------------
K
L
I
V
K
N
G
Y
V
I
D
P
S
Q
N
L
E
G
E
F
D
I
L
V
E
N
G
K
I
-
K
K
I
D
K
N
I
L
------------------
V
P
E
A
--
E
----------
I
I
D
A
K
G
L
I
V
C
P
G
F
I
D
I
H
V
H
L
R
D
P
--
G
Q
T
Y
K
E
D
I
E
S
G
S
R
C
A
V
A
G
G
F
T
T
I
V
C
M
--
P
-
N
T
N
P
P
-
I
D
N
T
T
V
V
N
Y
I
L
Q
K
S
K
--
S
V
G
L
C
R
V
L
P
T
G
T
I
T
K
---
G
--
R
--
K
GK
E
I
A
D
F
Y
S
L
K
E
A
G
C
V
A
F
--------
T
---
D
D
G
S
------
P
V
M
-
D
S
S
V
M
R
K
A
L
E
L
A
S
Q
L
-
G
V
----
P
I
M
D
--
H
-----------------------------------------------
A
E
E
I
Q
I
A
R
D
G
-----
I
L
A
Q
----
R
T
G
-
G
-
H
V
H
I
Q
H
V
S
T
K
L
S
L
E
I
I
E
F
F
K
E
K
G
V
K
I
T
C
E
V
N
P
N
H
L
L
-----------------------------
D
R
L
A
-
L
I
E
G
V
K
R
G
I
I
D
C
F
A
T
D
H
A
P
H
Q
T
-------------
M
P
----
G
I
I
G
L
Q
T
A
L
P
-
S
A
L
-
E
-
L
-
Y
R
K
G
I
I
S
L
K
K
L
I
E
M
F
T
I
N
P
A
R
I
--
I
G
V
--
D
--
L
G
T
L
K
L
G
S
P
A
D
I
T
I
F
D
P
N
K
E
W
I
L
N
E
E
T
N
L
S
K
S
R
N
T
P
L
W
G
K
V
L
K
G
K
V
I
Y
T
I
K
D
G
K
M
V
Y
K
D
-----------------------------------------
3
PsiBlast_PDB
90.18
42%
-68
- C2 -
3D6N
2
PYRC_AQUAE
A:
[3-420]
----------------
K
L
I
V
K
N
G
Y
V
I
D
P
S
Q
N
L
E
G
E
F
D
I
L
V
E
N
G
K
I
-
K
K
I
D
K
N
I
L
------------------
V
P
E
A
--
E
----------
I
I
D
A
K
G
L
I
V
C
P
G
F
I
D
I
H
V
H
L
R
D
P
--
G
Q
T
Y
K
E
D
I
E
S
G
S
R
C
A
V
A
G
G
F
T
T
I
V
C
M
--
P
-
N
T
N
P
P
-
I
D
N
T
T
V
V
N
Y
I
L
Q
K
S
K
--
S
V
G
L
C
R
V
L
P
T
G
T
I
T
K
---
G
--
R
--
K
GK
E
I
A
D
F
Y
S
L
K
E
A
G
C
V
A
F
--------
T
---
D
D
G
S
------
P
V
M
-
D
S
S
V
M
R
K
A
L
E
L
A
S
Q
L
-
G
V
----
P
I
M
D
--
H
C
E
D
---
D
K
L
-
A
---
Y
G
V
I
N
E
G
E
V
-----
S
A
L
L
G
L
S
S
R
A
P
-------
E
A
E
E
I
Q
I
A
R
D
G
-----
I
L
A
Q
----
R
T
G
-
G
-
H
V
H
I
Q
H
V
S
T
K
L
S
L
E
I
I
E
F
F
K
E
K
G
V
K
I
T
C
E
V
N
P
N
H
L
L
F
T
E
R
E
V
L
------
N
S
G
A
N
A
R
V
N
P
P
L
R
K
K
E
D
R
L
A
-
L
I
E
G
V
K
R
G
I
I
D
C
F
A
T
D
H
A
P
H
Q
T
F
E
K
E
L
----
V
E
F
A
M
P
----
G
I
I
G
L
Q
T
A
L
P
-
S
A
L
-
E
-
L
-
Y
R
K
G
I
I
S
L
K
K
L
I
E
M
F
T
I
N
P
A
R
I
--
I
G
V
--
D
--
L
G
T
L
K
L
G
S
P
A
D
I
T
I
F
D
P
N
K
E
W
I
L
N
E
E
T
N
L
S
K
S
R
N
T
P
L
W
G
K
V
L
K
G
K
V
I
Y
T
I
K
D
G
K
M
V
Y
K
D
-----------------------------------------
87
HHSearch
88.76
42%
-64
- C2 -
3GRI
5
PYRC_STAAW
A:
[1-422]
----------------
M
K
L
I
K
N
G
K
V
L
Q
N
G
--
E
L
Q
Q
A
D
I
L
I
D
G
K
V
I
-
K
Q
I
A
P
A
I
E
P
S
-------------------
N
G
V
D
----------
I
I
D
A
K
G
H
F
V
S
P
G
F
V
D
V
H
V
H
L
R
E
P
--
G
G
E
Y
K
E
T
I
E
T
G
T
K
A
A
A
R
G
G
F
T
T
V
C
P
M
--
P
-
N
T
R
P
V
-
P
D
S
V
E
H
F
E
A
L
Q
K
L
I
D
--
D
N
A
Q
V
R
V
L
P
Y
A
S
I
T
T
---
R
QL
G
--
K
--
E
L
V
D
F
P
A
L
V
K
E
G
A
F
A
F
--------
T
---
D
D
G
V
------
G
V
Q
-
T
A
S
M
M
Y
E
G
M
I
E
A
A
K
V
-
N
K
----
A
I
V
A
--
H
C
E
D
---
N
S
L
I
Y
---
G
G
A
M
H
E
G
K
R
-----
S
K
E
L
G
I
P
G
I
P
N
-------
I
C
E
S
V
Q
I
A
R
D
V
-----
L
L
A
E
----
A
-
A
-
G
C
H
Y
H
V
C
H
V
S
T
K
E
S
V
R
V
I
R
D
A
K
R
A
G
I
H
V
T
A
E
V
T
P
H
H
L
L
L
T
E
D
D
I
P
------
G
N
N
A
I
Y
K
M
N
P
P
L
R
S
T
E
D
R
E
A
-
L
L
E
G
L
L
D
G
T
I
D
C
I
A
T
D
H
A
P
H
A
R
D
E
K
A
Q
---
P
M
E
K
A
P
F
----
G
I
V
G
S
E
T
A
F
P
-
L
L
Y
T
H
-
F
-
V
K
N
G
D
W
T
L
Q
Q
L
V
D
Y
L
T
I
K
P
C
E
T
--
F
N
L
--
E
--
Y
G
T
L
K
E
N
G
Y
A
D
L
T
I
I
D
L
D
S
E
Q
E
I
K
G
E
D
F
L
S
K
A
D
N
T
P
F
I
G
Y
K
V
Y
G
N
P
I
L
T
M
V
E
G
E
V
K
F
E
G
-----------------------------------------
93
HHSearch
86.10
34%
-65
- C2 -
2Z00
2
?
A:
[1-425]
----------------
M
I
L
I
R
N
V
R
L
V
D
A
R
G
-
E
R
G
P
A
D
V
L
I
G
E
G
R
I
-
L
S
L
E
G
G
-----------------------
E
A
K
Q
----------
V
V
D
G
T
G
C
F
L
A
P
G
F
L
D
L
H
A
H
L
R
E
P
--
G
E
E
V
K
E
D
L
F
S
G
L
L
A
A
V
R
G
G
Y
T
D
L
V
S
M
--
P
-
N
T
K
P
P
-
V
D
T
P
E
A
V
R
A
L
K
E
K
A
K
--
A
L
G
L
A
R
L
H
P
A
A
A
L
T
E
---
K
QE
G
--
K
--
T
L
T
P
A
G
L
L
R
E
A
G
A
V
L
L
--------
T
---
D
D
G
R
------
T
N
E
-
D
A
G
V
L
A
A
G
L
L
M
A
A
P
L
-
G
L
----
P
V
A
V
--
H
A
E
D
---
A
G
L
R
R
---
N
G
V
M
N
D
G
P
L
-----
A
D
L
L
G
L
P
G
N
P
P
-------
E
A
E
A
A
R
I
A
R
D
L
-----
E
V
L
R
Y
A
L
R
R
S
P
A
T
P
R
L
H
V
Q
H
L
S
T
K
R
G
L
E
L
V
R
E
A
K
R
A
G
L
P
V
T
A
E
A
T
P
H
H
L
T
L
T
E
E
A
L
R
------
T
F
D
P
L
F
K
V
A
P
P
L
R
G
E
E
D
R
E
A
-
L
L
E
G
L
L
D
G
T
L
D
A
I
A
T
D
H
A
P
H
T
L
A
E
K
E
K
---
D
L
L
R
A
P
F
----
G
I
P
S
L
E
V
A
F
P
-
L
L
Y
T
E
-
L
-
H
L
K
R
G
F
P
L
Q
R
L
V
E
L
F
T
D
G
P
R
R
V
--
L
G
L
--
P
--
P
L
H
L
E
E
G
A
E
A
S
L
V
L
L
S
P
K
E
R
P
-
V
D
P
S
A
F
A
S
K
A
R
Y
S
P
W
A
G
W
V
L
G
G
W
P
V
L
T
L
V
A
G
R
I
V
H
E
A
L
----------------------------------------
6
PsiBlast_PDB
85.38
44%
-62
- C2 -
3GRI
5
PYRC_STAAW
A:
[37-420]
------------------------------------------------------
S
N
---------------
G
V
-----
D
----------
I
I
D
A
K
G
H
F
V
S
P
G
F
V
D
V
H
V
H
L
R
E
P
--
G
G
E
Y
K
E
T
I
E
T
G
T
K
A
A
A
R
G
G
F
T
T
V
C
P
M
--
P
-
N
T
R
P
V
-
P
D
S
V
E
H
F
E
A
L
Q
K
L
I
D
--
D
N
A
Q
V
R
V
L
P
Y
A
S
I
T
T
---
R
--
Q
LG
K
--
E
L
V
D
F
P
A
L
V
K
E
G
A
F
A
F
--------
T
---
D
D
G
V
------
G
V
Q
-
T
A
S
M
M
Y
E
G
M
I
E
A
A
K
V
-
N
K
----
A
I
V
A
--
H
C
E
D
---
N
S
L
I
Y
---
G
G
A
M
H
E
G
K
R
-----
S
K
E
L
G
I
P
G
I
P
N
-------
I
C
E
S
V
Q
I
A
R
D
V
-----
L
L
A
-----
E
A
A
-
G
C
H
Y
H
V
C
H
V
S
T
K
E
S
V
R
V
I
R
D
A
K
R
A
G
I
H
V
T
A
E
V
T
P
H
H
L
L
L
T
E
D
D
I
P
------
G
N
N
A
I
Y
K
M
N
P
P
L
R
S
T
E
D
R
E
A
-
L
L
E
G
L
L
D
G
T
I
D
C
I
A
T
D
H
A
P
H
A
R
D
E
K
A
Q
---
P
M
E
K
A
P
F
----
G
I
V
G
S
E
T
A
F
P
L
L
Y
T
-
H
-
F
-
V
K
N
G
D
W
T
L
Q
Q
L
V
D
Y
L
T
I
K
P
C
E
T
--
F
N
L
--
E
--
Y
G
T
L
K
E
N
G
Y
A
D
L
T
I
I
D
L
D
S
E
Q
E
I
K
G
E
D
F
L
S
K
A
D
N
T
P
F
I
G
Y
K
V
Y
G
N
P
I
L
T
M
V
E
G
E
V
K
F
E
G
-----------------------------------------
7
PsiBlast_PDB
82.36
34%
-54
- C2 -
2Z00
2
?
A:
[6-422]
---------------------
N
V
R
L
V
D
A
R
G
E
R
G
P
A
D
V
L
I
G
E
G
R
I
L
S
L
E
G
G
E
A
-------------------------
K
Q
----------
V
V
D
G
T
G
C
F
L
A
P
G
F
L
D
L
H
A
H
L
R
E
P
--
G
E
E
V
K
E
D
L
F
S
G
L
L
A
A
V
R
G
G
Y
T
D
L
V
S
M
--
P
-
N
T
K
P
P
-
V
D
T
P
E
A
V
R
A
L
K
E
K
A
K
--
A
L
G
L
A
R
L
H
P
A
A
A
L
T
E
---
K
--
Q
--
E
GK
T
L
T
P
A
G
L
L
R
E
A
G
A
V
L
L
--------
T
---
D
D
G
R
------
T
N
E
-
D
A
G
V
L
A
A
G
L
L
M
A
A
P
L
-
G
L
----
P
V
A
V
--
H
A
E
D
---
A
G
L
R
R
---
N
G
V
M
N
D
G
P
L
-----
A
D
L
L
G
L
P
G
N
P
P
-------
E
A
E
A
A
R
I
A
R
D
L
E
V
L
R
Y
A
L
R
R
----
S
P
A
-
T
P
R
L
H
V
Q
H
L
S
T
K
R
G
L
E
L
V
R
E
A
K
R
A
G
L
P
V
T
A
E
A
T
P
H
H
L
T
L
T
E
E
A
L
R
------
T
F
D
P
L
F
K
V
A
P
P
L
R
G
E
E
D
R
E
A
-
L
L
E
G
L
L
D
G
T
L
D
A
I
A
T
D
H
A
P
H
T
L
A
E
K
E
K
---
D
L
L
R
A
P
F
----
G
I
P
S
L
E
V
A
F
P
L
L
Y
T
-
E
-
L
-
H
L
K
R
G
F
P
L
Q
R
L
V
E
L
F
T
D
G
P
R
R
V
--
L
G
L
--
P
--
P
L
H
L
E
E
G
A
E
A
S
L
V
L
L
S
-
P
K
E
R
P
V
D
P
S
A
F
A
S
K
A
R
Y
S
P
W
A
G
W
V
L
G
G
W
P
V
L
T
L
V
A
G
R
I
V
H
E
A
L
----------------------------------------
95
HHSearch
80.46
28%
-64
- C2 -
3HM7
1
ALLB_BACHD
A:
[5-440]
--------------
R
F
D
L
I
I
R
S
S
T
V
V
T
E
T
T
--
T
Y
R
A
D
V
A
I
R
N
G
I
V
-
S
A
I
T
E
P
G
S
I
S
------------------
S
D
D
G
P
----------
A
I
D
G
T
G
L
H
L
F
P
G
M
V
D
V
H
V
H
F
N
E
P
--
G
R
T
E
W
E
G
F
A
S
G
S
K
S
L
A
A
G
G
V
T
T
Y
F
D
M
--
P
-
L
N
S
N
P
P
T
I
T
R
E
E
L
D
K
K
R
Q
L
A
N
--
E
K
S
L
V
D
Y
R
F
W
G
G
L
V
P
---------
G
--
N
I
D
H
L
Q
D
L
H
D
G
G
V
I
G
F
--------
K
---
A
F
M
S
ECGTDD
F
Q
F
S
H
D
E
T
L
L
K
G
M
K
K
I
A
A
L
-
G
S
----
I
L
A
V
--
H
A
E
S
---
N
E
M
V
N
A
L
T
T
I
A
I
E
E
Q
R
L
-----
T
V
K
D
Y
S
E
A
R
P
I
-------
V
S
E
L
E
A
V
E
R
I
L
-----
R
F
A
Q
----
L
-
T
-
C
C
P
I
H
I
C
H
V
S
S
R
K
V
L
K
R
I
K
Q
A
K
G
E
G
V
N
V
S
V
E
T
C
P
H
Y
L
L
F
S
L
D
E
F
A
------
E
I
G
Y
L
A
K
C
A
P
P
L
R
E
R
Q
E
V
E
D
-
L
W
D
G
L
M
A
G
E
I
D
L
I
S
S
D
H
S
P
S
L
P
Q
M
K
T
G
K--
T
I
F
E
V
W
G
----
G
I
A
G
C
Q
N
T
L
A
-
V
M
L
T
E
-
G
-
Y
H
K
R
K
M
P
L
T
Q
I
V
Q
L
L
S
T
E
P
A
K
R
--
F
G
L
--
Y
PQ
K
G
T
I
Q
V
G
A
E
A
S
F
T
L
I
D
L
N
E
S
Y
T
L
N
A
S
D
L
Y
Y
R
H
P
I
S
P
Y
V
G
Q
R
F
R
G
K
V
K
H
T
I
C
Q
G
K
H
V
Y
Q
D
H
----------------------------------------
82
Fugue
79.08
24%
-63
- C2 -
4TQT
8
?
A:
[14-490]
--------------
A
S
K
V
I
K
-
G
G
T
V
I
T
A
D
R
--
T
F
R
A
D
I
L
I
E
D
G
K
I
-
A
A
I
G
D
S
L
E
G
----------------------
D
E
----------
V
I
D
A
S
G
C
Y
V
M
P
G
G
I
D
P
H
T
H
L
Q
M
P
FM
G
T
Y
S
S
D
D
F
D
T
G
T
A
A
A
L
A
G
G
T
T
M
V
V
D
F
V
L
P
-
D
S
E
G
N
-
L
L
D
A
L
Q
E
W
F
Q
K
A
G
K
A
--
R
T
---
D
Y
S
F
H
M
A
I
T
G
W--
N
--
E
--
R
--
T
F
N
E
M
A
E
V
V
K
R
G
I
N
T
F
--------
H
FMA
Y
K
G
A
------
L
M
V
-
N
D
D
E
M
F
A
S
F
Q
R
C
A
E
L
G
A
M
----
P
L
V
H
AE
N
G
D
I
---
V
A
Q
L
Q
---
A
K
L
M
A
E
G
N
D
-----
G
P
E
A
H
A
Y
S
R
P
P
-------
E
V
E
G
E
A
T
N
R
A
I
-----
M
I
A
D
----
Q
A
--
G
V
P
L
Y
V
V
H
V
S
C
E
Q
S
H
E
A
I
R
R
A
R
Q
K
G
M
R
V
F
G
E
P
L
I
Q
H
L
T
L
D
E
S
E
Y
H
NRD
W
--
D
Y
A
A
R
R
V
M
S
P
P
F
R
D
K
L
N
Q
D
S
-
L
W
A
G
L
A
A
G
S
L
Q
C
V
A
T
D
H
C
A
F
T
T
E
Q
K
R
Y
GIG
N
F
T
K
I
P
N
----
G
T
G
G
L
E
E
R
M
P
-
V
L
W
-
T
-
R
G
V
R
T
G
R
L
T
P
N
E
F
V
A
V
T
S
T
N
I
A
K
I
--
L
N
I
YP
Q
--
K
G
A
V
V
P
G
A
D
A
D
L
V
I
W
D
P
E
T
T
K
K
I
S
A
K
T
Q
H
S
S
I
D
Y
N
V
F
E
G
F
E
L
K
G
L
P
I
M
T
L
S
R
G
R
I
A
F
D
K
G
QVTAKPGD
G
R
F
I
E
R
E
P
NG
A
V
N
R
A
L
S
Q
W
K
E
I
V
A
P
R
K
V
E
R
S
A
13
PsiBlast_PDB
78.19
23%
-60
- C2 -
4GZ7
3
?
A:
[5-446]
-----------------------------------
G
E
I
L
I
K
G
G
K
V
-
V
N
E
D
C
S
F
F
S
D
V
H
I
R
GGKIV
E
V
G
P
D
L
R
V
P
P
G
A
-
R
----------
V
I
D
A
T
D
R
L
V
I
P
G
G
I
D
T
H
T
H
M
E
L
A
FM
G
T
R
A
V
D
D
F
H
I
G
T
K
A
A
L
A
G
G
T
T
M
I
L
D
F
--
V
-
M
T
Q
K
G
---
Q
S
L
L
E
A
Y
D
L
W
R
K
T
--
A
D
P
K
V
C
C
D
Y
S
L
H
V
A
V
TWW
S
--
D
--
E
--
V
K
D
E
M
R
T
L
A
Q
E
R
G
V
N
S
--------
F
---
K
M
F
M
------
A
Y
K
-
G
L
F
M
L
R
D
D
E
L
Y
A
V
F
S
-
H
C
K
E
V
G
A
I
A
Q
V
-
H
A
E
N
---
G
D
L
I
A
---
E
G
A
----
K
K
-----
M
L
S
L
G
I
T
G
P
E
G
H
E
L
C
RP
E
A
V
E
A
E
A
T
Q
R
A
I
-----
T
I
A
S
----
A
V
--
N
C
P
L
Y
V
V
H
V
M
S
K
S
A
A
D
V
V
S
K
A
R
K
D
G
R
V
V
F
G
E
--
P
I
A
A
S
L
G
T
D
G
T
N
YWHKD
W
A
H
A
A
Q
Y
V
M
G
P
P
L
R
P
D
P
S
T
P
G
Y
L
M
D
L
L
A
N
D
D
L
T
L
T
G
T
D
N
C
T
F
S
R
C
Q
K
A
L
GKD
D
F
T
R
I
P
N
----
G
V
N
G
V
E
D
R
M
S
-
V
I
W
-
E
-
K
G
V
H
S
G
K
M
D
E
N
R
F
V
A
V
T
S
S
N
A
A
K
I
--
F
N
F
YP
Q
--
K
G
R
I
A
K
D
S
D
A
D
V
V
I
W
D
P
K
T
T
R
K
I
S
A
Q
T
H
H
Q
A
V
D
Y
N
I
F
E
G
M
E
C
H
G
V
P
V
V
T
V
S
R
G
R
V
V
Y
E
E
G
----------------------------------------
24
PsiBlast_CBE
76.34
31%
-67
- C2 -
3HM7
1
ALLB_BACHD
E:
[30-437]
-------------------------------------------------------
N
---------------
G
I
V
S
A
I
T
E
PGSISSDDGP
A
I
D
G
T
G
L
H
L
F
P
G
M
V
D
V
H
V
H
F
N
E
P
--
G
R
T
E
W
E
G
F
A
S
G
S
K
S
L
A
A
G
G
V
T
T
Y
F
D
M
--
P
L
N
S
N
P
P
---
T
I
T
R
E
E
L
D
K
K
R
Q
L
AN
E
K
S
L
V
D
Y
R
F
W
G
G
L
V
P
---
G
--------
N
I
D
H
L
Q
D
L
H
D
G
G
V
I
G
F
KAFMSECG
T
---
D
D
-
F
------
Q
F
S
-
H
D
E
T
L
L
K
G
M
K
K
I
A
A
L
-
G
S
----
I
L
A
V
--
H
A
E
S
NEM
V
N
A
L
T
---
T
I
A
I
E
E
Q
R
L
TVKDY
S
E
A
---
R
P
I
V
S
-------
E
L
E
A
V
---
E
R
I
-----
L
R
F
A
----
Q
L
T
-
C
C
P
I
H
I
C
H
V
S
S
R
K
V
L
K
R
I
K
Q
A
K
G
E
G
V
N
V
S
V
E
T
C
P
H
Y
L
L
F
S
L
D
E
F
A
------
E
I
G
Y
L
A
K
C
A
P
P
L
R
E
R
Q
E
V
E
D
-
L
W
D
G
L
M
A
G
E
I
D
L
I
S
S
D
H
S
P
---
S
L
P
Q
M
---
K
T
G
K
T
I
F
EVWG
G
I
A
G
C
Q
N
T
L
A
-
V
M
L
T
E
-
G
-
Y
H
K
R
K
M
P
L
T
Q
I
V
Q
L
L
S
T
E
P
A
K
R
FG
L
Y
P
--
Q
--
K
G
T
I
Q
V
G
A
E
A
S
F
T
L
I
D
L
N
E
S
Y
T
L
N
A
S
D
L
Y
Y
R
H
P
I
S
P
Y
V
G
Q
R
F
R
G
K
V
K
H
T
I
C
Q
G
K
H
V
Y
Q
D
H
----------------------------------------
23
PsiBlast_CBE
75.97
31%
-67
- C2 -
3HM7
1
ALLB_BACHD
F:
[30-437]
-------------------------------------------------------
N
---------------
G
I
V
S
A
I
T
E
PGSISSDDGP
A
I
D
G
T
G
L
H
L
F
P
G
M
V
D
V
H
V
H
F
N
E
P
--
G
R
T
E
W
E
G
F
A
S
G
S
K
S
L
A
A
G
G
V
T
T
Y
F
D
M
--
P
L
N
S
N
P
P
---
T
I
T
R
E
E
L
D
K
K
R
Q
L
AN
E
K
S
L
V
D
Y
R
F
W
G
G
L
V
P
---
G
--------
N
I
D
H
L
Q
D
L
H
D
G
G
V
I
G
F
KAFMSECG
T
---
D
D
-
F
------
Q
F
S
-
H
D
E
T
L
L
K
G
M
K
K
I
A
A
L
-
G
S
----
I
L
A
V
--
H
A
E
S
NEM
V
N
A
L
T
---
T
I
A
I
E
E
Q
R
L
TVKDY
S
E
A
---
R
P
I
V
S
-------
E
L
E
A
V
---
E
R
I
-----
L
R
F
A
----
Q
L
T
-
C
C
P
I
H
I
C
H
V
S
S
R
K
V
L
K
R
I
K
Q
A
K
G
E
G
V
N
V
S
V
E
T
C
P
H
Y
L
L
F
S
L
D
E
F
A
------
E
I
G
Y
L
A
K
C
A
P
P
L
R
E
R
Q
E
V
E
D
-
L
W
D
G
L
M
A
G
E
I
D
L
I
S
S
D
H
S
P
---
S
L
P
Q
M
---
K
T
G
K
T
I
F
EVWG
G
I
A
G
C
Q
N
T
L
A
-
V
M
L
T
E
-
G
-
Y
H
K
R
K
M
P
L
T
Q
I
V
Q
L
L
S
T
E
P
A
K
R
FG
L
Y
P
--
Q
--
K
G
T
I
Q
V
G
A
E
A
S
F
T
L
I
D
L
N
E
S
Y
T
L
N
A
S
D
L
Y
Y
R
H
P
I
S
P
Y
V
G
Q
R
F
R
G
K
V
K
H
T
I
C
Q
G
K
H
V
Y
Q
D
H
----------------------------------------
25
PsiBlast_CBE
75.83
31%
-65
- C2 -
3HM7
1
ALLB_BACHD
D:
[30-437]
-------------------------------------------------------
N
---------------
G
I
V
S
A
I
T
E
PGSISSDDGP
A
I
D
G
T
G
L
H
L
F
P
G
M
V
D
V
H
V
H
F
N
E
P
--
G
R
T
E
W
E
G
F
A
S
G
S
K
S
L
A
A
G
G
V
T
T
Y
F
D
M
--
P
L
N
S
N
P
P
---
T
I
T
R
E
E
L
D
K
K
R
Q
L
AN
E
K
S
L
V
D
Y
R
F
W
G
G
L
V
P
---
G
--------
N
I
D
H
L
Q
D
L
H
D
G
G
V
I
G
F
KAFMSECG
T
---
D
D
-
F
------
Q
F
S
-
H
D
E
T
L
L
K
G
M
K
K
I
A
A
L
-
G
S
----
I
L
A
V
--
H
A
E
S
NEM
V
N
A
L
T
---
T
I
A
I
E
E
Q
R
L
TVKDY
S
E
A
---
R
P
I
V
S
-------
E
L
E
A
V
---
E
R
I
-----
L
R
F
A
----
Q
L
T
-
C
C
P
I
H
I
C
H
V
S
S
R
K
V
L
K
R
I
K
Q
A
K
G
E
G
V
N
V
S
V
E
T
C
P
H
Y
L
L
F
S
L
D
E
F
A
------
E
I
G
Y
L
A
K
C
A
P
P
L
R
E
R
Q
E
V
E
D
-
L
W
D
G
L
M
A
G
E
I
D
L
I
S
S
D
H
S
P
---
S
L
P
Q
M
---
K
T
G
K
T
I
F
EVWG
G
I
A
G
C
Q
N
T
L
A
-
V
M
L
T
E
-
G
-
Y
H
K
R
K
M
P
L
T
Q
I
V
Q
L
L
S
T
E
P
A
K
R
FG
L
Y
P
--
Q
--
K
G
T
I
Q
V
G
A
E
A
S
F
T
L
I
D
L
N
E
S
Y
T
L
N
A
S
D
L
Y
Y
R
H
P
I
S
P
Y
V
G
Q
R
F
R
G
K
V
K
H
T
I
C
Q
G
K
H
V
Y
Q
D
H
----------------------------------------
8
PsiBlast_PDB
75.78
31%
-68
- C2 -
3HM7
1
ALLB_BACHD
A:
[30-437]
-------------------------------------------------------
N
---------------
G
I
V
S
A
I
T
E
P
GSISSDD
G
P
A
I
D
G
T
G
L
H
L
F
P
G
M
V
D
V
H
V
H
F
N
E
P
--
G
R
T
E
W
E
G
F
A
S
G
S
K
S
L
A
A
G
G
V
T
T
Y
F
D
M
--
P
L
N
S
N
P
P
---
T
I
T
R
E
E
L
D
K
K
R
Q
L
A
N
E
K
S
L
V
D
Y
R
F
W
G
G
L
V
P
---
G
--------
N
I
D
H
L
Q
D
L
H
D
G
G
V
I
G
F
K
A
F
MSECG
T
---
D
D
-
F
------
Q
F
S
-
H
D
E
T
L
L
K
G
M
K
K
I
A
A
L
-
G
S
----
I
L
A
V
--
H
A
E
S
NEM
V
N
A
L
T
---
T
I
A
I
E
E
Q
R
L
T
V
K
D
Y
S
E
A
---
R
P
I
V
S
-------
E
L
E
A
V
---
E
R
I
-----
L
R
F
A
----
Q
L
T
-
C
C
P
I
H
I
C
H
V
S
S
R
K
V
L
K
R
I
K
Q
A
K
G
E
G
V
N
V
S
V
E
T
C
P
H
Y
L
L
F
S
L
D
E
F
A
------
E
I
G
Y
L
A
K
C
A
P
P
L
R
E
R
Q
E
V
E
D
-
L
W
D
G
L
M
A
G
E
I
D
L
I
S
S
D
H
S
P
---
S
L
P
Q
M
---
K
T
G
K
T
I
F
EVW
G
G
I
A
G
C
Q
N
T
L
A
-
V
M
L
T
E
-
G
-
Y
H
K
R
K
M
P
L
T
Q
I
V
Q
L
L
S
T
E
P
A
K
R
F
G
L
Y
P
--
Q
--
K
G
T
I
Q
V
G
A
E
A
S
F
T
L
I
D
L
N
E
S
Y
T
L
N
A
S
D
L
Y
Y
R
H
P
I
S
P
Y
V
G
Q
R
F
R
G
K
V
K
H
T
I
C
Q
G
K
H
V
Y
Q
D
H
----------------------------------------