@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Wbm0456: (2015-12-01 )
MEQKQSKSVAIWLFLCSIMIVLMVGIGGFTRLSKAGLSITEWNPITGAFPPLNERDWLQEKSKYETTPEYKTFNYGMSMEEFRTLYLIEYVHRLFARLTGLIFILPFIYFTLKKRISKKVVIRLSIALSFGVLQAFTGWYMVKSGLVAKPHVSHYMLTLHLLLALVIFALLSYQFFNYQVRQKQTKLKISGSTVHYVGIILILIVVQIIFGAFVAGLNAGLIYNTFPLMGGHIIPKDLFFLQPTWLNIFENRATVQFIHRTLALLILVLTTVLTIKNASVKSVYVMLLSVIIQIILGVVTLLLHIPITIAISHQMFSFILFGSGLCFLCYLRKQN
Atome Classification :
(20 SA)
.........10----........--20........30........40.......------.50........60......-..70.-----------.......80......--------.-----.90........100---------------------------------------..--.....110.......120.......130.......--------140.......150.......160.......170.--.----------.....180.......190.......200.......210--........220.....------..230.......240.......250........260--.........270.......280.......290.......300.......310.......320..---------.....330...---------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MEQKQSK
S
V
A
I
----
W
L
F
L
C
S
I
M
--
I
V
L
M
VGIG
G
F
T
R
L
S
KAGLSITEWNPITGA------FPPL
N
E
R
D
W
L
Q
E
KSKYETT-PEYKT-----------FNYGM
S
M
E
E
F
R
T
L
Y
L
--------
I
-----
E
Y
V
H
R
L
F
A
R
L
T
G
L
I
---------------------------------------
F
I
--
L
P
F
I
Y
F
T
L
K
K
RIS
K
K
V
V
I
R
L
S
I
A
L
S
F
G
V
L
Q
A
F
T
G
W
--------
Y
M
VKSGLVAKP
H
V
S
H
Y
M
L
T
L
H
L
L
L
A
L
V
I
F
A
L
L
S
Y
--
Q
----------
F
F
N
Y
Q
V
R
Q
K
Q
T
K
L
K
ISGS
T
V
H
Y
V
G
I
I
L
I
L
I
V
V
Q
I
I
F
G
---
A
F
V
A
G
LNA
G
L
I
Y
NTFP------LMGGHIIPK
D
L
F
F
LQ
P
T
W
L
N
I
FEN-R
A
T
V
Q
F
I
H
R
----
T
L
A
L
L
I
L
V
L
T
T
V
L
T
IKNA
S
V
K
S
V
Y
V
M
L
L
S
V
I
I
Q
I
I
L
G
V
V
T
L
L
L
HI
P
I
T
I
A
I
S
H
Q
M
F
S
F
I
L
FGS
G
---------
L
C
F
L
C
Y
L
RKQN---------------------------------------------
32
Fugue
87.28
17%
-142
- C6 -
5A1F
14
KDM5B_HUMAN
A:
[1-458]
S
M
F
L
P
P
P
E
C
P
V
F
E
P
S
W
E
E
F
A
D
P
F
A
F
I
H
K
I
R
P
I
A
E
Q
T
G
I
C
K
V
R
P
P
-
P
D
W
Q
P
P
F
A
C
D
VDK
L
H
F
T
P
R
I
Q
R
--
L
N
E
L
E
A
Q
T
R
V
-
R
D
Y
T
L
-----------
R
T
F
G
E
M
A
D
A
F
K
S
D
Y
F
NMPVHMVP
T
-----
E
L
V
E
K
E
F
W
R
L
V
S
T
I
EED
V
T
V
E
Y
G
A
D
I
A
SKEFGSG
F
P
V
R
DS
P
E
E
E
E
Y
L
D
SGWNL
N
N
--
M
P
V
M
E
Q
S
V
L
A
H
I
T
A
D
I
C
G
M
K
L
P
W
L
Y
V
G
M
C
F
S
S
F
C
W
--------
H
I
E
D
-------
H
W
S
Y
S
I
N
Y
L
H
W
G
E
P
K
T
W
Y
G
V
P
G
Y
A
A
E
----------
Q
L
E
N
V
M
K
K
L
A
P
E
L
F
V
S
Q
P
D
L
L
H
Q
-
L
V
T
I
M
N
P
N
T
L
M
T
H
EV
P
V
Y
R
T
N
Q
C
A
G
E
F
V
I
T
F
P
R
A
Y
H
S
G
F
N
Q
G
F
N
F
A
E
A
V
N
F
C
T
V
D
W
L
P
L
G
R
Q
C
V
E
H
Y
R
L
L
H
R
YCVF
S
H
D
E
M
I
C
K
M
A
S
K
A
D
V
L
D
V
V
V
A
S
T
V
Q
K
D
M
A
I
M
I
E
D
E
K
A
L
R
E
T
V
R
K
L
G
V
---
I
D
S
E
R
M
D
F
E
L
L
P
D
D
ERQCVKCKT
T
C
F
M
S
A
I
S
C
S
C
KPG
L
L
V
C
LHHVKELCSCPPYKYKLRYRYT
L
D
D
L
Y
P
M
M
N
A
L
K
L
R
A
E
20
PsiBlast_PDB
53.36
23%
-92
- C7 -
4NPV
2
PDE1B_HUMAN
A:
[143-235]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
C
A
I
V
Y
N
D
R
S
------
V
L
E
N
H
H
I
S
S
V
F
R
L
M
Q
D
D
E
M
N
I
F
I
N
-
L
T
K
D
E
F
V
E
L
----
R
A
L
V
I
E
M
V
L
A
T
D
M
S
C
H
F
Q
Q
V
K
T
M
K
T
A
L
Q
Q
L
E
R
I
D
K
P
K
A
L
S
L
L
L
H
---
A
A
D
I
S
H
P
T
K
Q
W
L
V
H
S
R
W
---------
T
K
A
L
M
E
E
F
F
R
Q
---------------------------------------------
29
Fugue
48.17
11%
-67
- C6 -
2BHW
20
CB22_PEA
A:
[10-232]
------------------------------------------------
A
S
S
G
S
P
------
W
Y
G
P
D
R
V
K
Y
L
G
P
F
S
G
--
E
S
-
P
S
Y
L
T
GEFPGDYGWDT
A
G
L
S
A
D
P
E
T
F
S
K
N
R
E
--------
L
-----
E
V
I
H
S
R
W
A
M
L
G
A
L
G
---------------------------------------
S
V
--
F
P
E
L
L
S
R
N
G
V
K
F
G
E
A
V
W
F
K
A
G
S
Q
I
F
S
E
G
G
L
D
Y
L
G
N
--------
P
S
L
V
H
A
Q
S
I
L
A
I
W
A
T
Q
V
I
L
M
G
A
V
E
G
Y
R
I
A
G
G
P
L
G
--
E
VVDPLYPGGS
F
D
P
L
G
L
A
D
D
P
E
A
F
A
E
L
K
V
K
E
L
K
N
G
R
L
A
M
F
S
M
F
G
F
F
V
Q
---
A
I
V
T
G
------
K
G
P
L
E
------
N
L
A
D
H
L
A
D
P
V
N
N
N
A
W
S
Y
A
T
N
F
V
P
G
-
K
---------------------------------------------------------------------------------------------------------------------------------------------
33
Fugue
45.85
17%
12
- C6 -
1G3P
1
?
?:
[92-217]
-----------------------------------
E
Y
G
D
T
P
I
P
G
Y
T
Y
I
N
P
L
D
G
T
------
Y
P
P
G
T
E
Q
N
P
A
N
P
N
P
S
L
E
E
S
-
Q
P
L
N
T
-----------
F
M
F
--------
Q
N
N
R
--------
F
-----
R
N
R
Q
G
A
L
T
V
Y
T
G
T
V
---------------------------------------
T
Q
G
T
D
P
V
K
T
Y
Y
Q
Y
T
P
V
S
S
K
A
M
Y
D
A
Y
W
N
G
K
F
R
D
C
A
F
H
S
G
F
NEDIFVCE
Y
Q
G
Q
S
S
D
L
P
Q
P
P
V
N
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
Fugue
43.59
21%
-16
* C6 *
1BW5
-
A:
[1-66]
----------------------------------------------------------------------------
M
K
T
-
T
R
V
R
T
-----------
V
L
N
E
K
Q
L
H
T
L
R
T
C
Y
A
--------
A
NPRPD
A
L
M
K
E
Q
L
V
E
M
T
G
L
S
---------------------------------------
P
R
--
V
I
R
V
W
F
Q
N
K
R
C
K
D
K
K
R
S
I
M
M
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
Fugue
42.92
30%
537
- C5 -
3JQO
-
?
C:
[3-28]
---------------------------------------------------
S
G
H
------
K
P
P
-
P
E
P
D
W
S
N
T
V
P
V
N
K
T
I
-
P
V
D
T
Q
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
41.48
28%
73
- C7 -
2K85
-
A:
[26-66]
----------------------------------------------------------------
H
N
E
N
W
L
S
V
S
R
K
M
Q
A
S
-
P
E
Y
Q
D
-----------
Y
V
Y
L
E
G
T
Q
K
A
K
K
L
F
L
--------------
Q
H
I
H
R
L
K
H
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
Fugue
39.96
20%
381
* C7 *
1VZJ
1
ACES_HUMAN
A:
[3-28]
-------------------------------------------------------------
L
D
E
A
E
R
Q
W
K
A
E
F
H
R
W
S
S
Y
M
V
H
W
K
N
-----------
Q
F
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
39.41
60%
283
- C7 -
3Q14
-
TMOA_PSEME
A:
[344-361]
-----------------------------------------------
W
N
P
A
A
G
V
------
T
P
--
E
E
R
D
W
L
E
E
K
Y
P
G
W
N
K
-
R
W
G
R
C
-----------
W
D
V
I
T
E
N
V
L
N
D
R
M
D
L
--------
V
-----
S
P
E
T
L
P
S
V
C
N
M
S
Q
I
---------------------------------------
P
L
--
V
G
V
P
G
D
D
W
N
I
E
V
F
S
L
E
H
N
G
R
L
Y
H
F
G
S
E
V
D
R
W
V
F
Q
Q
--------
D
P
V
Q
Y
Q
N
H
M
N
I
V
D
R
F
L
A
G
Q
I
Q
P
M
T
L
E
G
A
L
K
Y
M
G
F
--
Q
----------
S
I
E
E
M
G
K
D
A
H
D
F
A
W
A
D
K
C
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
39.26
60%
279
- C7 -
3I5J
-
TMOA_PSEME
A:
[344-361]
-----------------------------------------------
W
N
P
A
A
G
V
------
T
P
--
E
E
R
D
W
L
E
E
K
Y
P
G
W
N
K
-
R
W
G
R
C
-----------
W
D
V
I
T
E
N
V
L
N
D
R
M
D
L
--------
V
-----
S
P
E
T
L
P
S
V
C
N
M
S
Q
I
---------------------------------------
P
L
--
V
G
V
P
G
D
D
W
N
I
E
V
F
S
L
E
H
N
G
R
L
Y
H
F
G
S
E
V
D
R
W
V
F
Q
Q
--------
D
P
V
Q
Y
Q
N
H
M
N
I
V
D
R
F
L
A
G
Q
I
Q
P
M
T
L
E
G
A
L
K
Y
M
G
F
--
Q
----------
S
I
E
E
M
G
K
D
A
H
D
F
A
W
A
D
K
C
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
39.09
60%
276
- C7 -
3RI7
-
TMOA_PSEME
A:
[343-360]
-----------------------------------------------
W
N
P
A
A
G
V
------
T
P
--
E
E
R
D
W
L
E
E
K
Y
P
G
W
N
K
-
R
W
G
R
C
-----------
W
D
V
I
T
E
N
V
L
N
D
R
M
D
L
--------
V
-----
S
P
E
T
L
P
S
V
C
N
M
S
Q
I
---------------------------------------
P
L
--
V
G
V
P
G
D
D
W
N
I
E
V
F
S
L
E
H
N
G
R
L
Y
H
F
G
S
E
V
D
R
W
V
F
Q
Q
--------
D
P
V
Q
Y
Q
N
H
M
N
I
V
D
R
F
L
A
G
Q
I
Q
P
M
T
L
E
G
A
L
K
Y
M
G
F
--
Q
----------
S
I
E
E
M
G
K
D
A
H
D
F
A
W
A
D
K
C
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
38.96
60%
279
- C7 -
3GE3
-
TMOA_PSEME
A:
[344-361]
-----------------------------------------------
W
N
P
A
A
G
V
------
T
P
--
E
E
R
D
W
L
E
E
K
Y
P
G
W
N
K
-
R
W
G
R
C
-----------
W
D
V
I
T
E
N
V
L
N
D
R
M
D
L
--------
V
-----
S
P
E
T
L
P
S
V
C
N
M
S
Q
I
---------------------------------------
P
L
--
V
G
V
P
G
D
D
W
N
I
E
V
F
S
L
E
H
N
G
R
L
Y
H
F
G
S
E
V
D
R
W
V
F
Q
Q
--------
D
P
V
Q
Y
Q
N
H
M
N
I
V
D
R
F
L
A
G
Q
I
Q
P
M
T
L
E
G
A
L
K
Y
M
G
F
--
Q
----------
S
I
E
E
M
G
K
D
A
H
D
F
A
W
A
D
K
C
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
38.96
60%
266
- C7 -
3DHI
-
TMOA_PSEME
A:
[344-361]
-----------------------------------------------
W
N
P
A
A
G
V
------
T
P
--
E
E
R
D
W
L
E
E
K
Y
P
G
W
N
K
-
R
W
G
R
C
-----------
W
D
V
I
T
E
N
V
L
N
D
R
M
D
L
--------
V
-----
S
P
E
T
L
P
S
V
C
N
M
S
Q
I
---------------------------------------
P
L
--
V
G
V
P
G
D
D
W
N
I
E
V
F
S
L
E
H
N
G
R
L
Y
H
F
G
S
E
V
D
R
W
V
F
Q
Q
--------
D
P
V
Q
Y
Q
N
H
M
N
I
V
D
R
F
L
A
G
Q
I
Q
P
M
T
L
E
G
A
L
K
Y
M
G
F
--
Q
----------
S
I
E
E
M
G
K
D
A
H
D
F
A
W
A
D
K
C
K
P
A
M
K
K
S
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
38.93
60%
279
- C7 -
3DHH
-
TMOA_PSEME
A:
[344-361]
-----------------------------------------------
W
N
P
A
A
G
V
------
T
P
--
E
E
R
D
W
L
E
E
K
Y
P
G
W
N
K
-
R
W
G
R
C
-----------
W
D
V
I
T
E
N
V
L
N
D
R
M
D
L
--------
V
-----
S
P
E
T
L
P
S
V
C
N
M
S
Q
I
---------------------------------------
P
L
--
V
G
V
P
G
D
D
W
N
I
E
V
F
S
L
E
H
N
G
R
L
Y
H
F
G
S
E
V
D
R
W
V
F
Q
Q
--------
D
P
V
Q
Y
Q
N
H
M
N
I
V
D
R
F
L
A
G
Q
I
Q
P
M
T
L
E
G
A
L
K
Y
M
G
F
--
Q
----------
S
I
E
E
M
G
K
D
A
H
D
F
A
W
A
D
K
C
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
Fugue
38.84
11%
141
- C7 -
1DML
-
DPOL_HHV1A
B:
[1200-1235]
----------------------------------------------------------------------
D
D
V
A
A
R
L
R
A
-
A
G
F
G
A
-----------
V
G
A
G
A
T
A
E
E
T
R
R
M
L
H
--------
R
-----
A
F
D
T
L
A
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
38.84
60%
284
- C7 -
3Q3N
-
TMOA_PSEME
A:
[344-361]
-----------------------------------------------
W
N
P
A
A
G
V
------
T
P
--
E
E
R
D
W
L
E
E
K
Y
P
G
W
N
K
-
R
W
G
R
C
-----------
W
D
V
I
T
E
N
V
L
N
D
R
M
D
L
--------
V
-----
S
P
E
T
L
P
S
V
C
N
M
S
Q
I
---------------------------------------
P
L
--
V
G
V
P
G
D
D
W
N
I
E
V
F
S
L
E
H
N
G
R
L
Y
H
F
G
S
E
V
D
R
W
V
F
Q
Q
--------
D
P
V
Q
Y
Q
N
H
M
N
I
V
D
R
F
L
A
G
Q
I
Q
P
M
T
L
E
G
A
L
K
Y
M
G
F
--
Q
----------
S
I
E
E
M
G
K
D
A
H
D
F
A
W
A
D
K
C
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
38.82
60%
281
- C7 -
3I63
-
TMOA_PSEME
A:
[344-361]
-----------------------------------------------
W
N
P
A
A
G
V
------
T
P
--
E
E
R
D
W
L
E
E
K
Y
P
G
W
N
K
-
R
W
G
R
C
-----------
W
D
V
I
T
E
N
V
L
N
D
R
M
D
L
--------
V
-----
S
P
E
T
L
P
S
V
C
N
M
S
Q
I
---------------------------------------
P
L
--
V
G
V
P
G
D
D
W
N
I
E
V
F
S
L
E
H
N
G
R
L
Y
H
F
G
S
E
V
D
R
W
V
F
Q
Q
--------
D
P
V
Q
Y
Q
N
H
M
N
I
V
D
R
F
L
A
G
Q
I
Q
P
M
T
L
E
G
A
L
K
Y
M
G
F
--
Q
----------
S
I
E
E
M
G
K
D
A
H
D
F
A
W
A
D
K
C
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
38.40
60%
282
- C7 -
3Q3M
-
TMOA_PSEME
A:
[344-361]
-----------------------------------------------
W
N
P
A
A
G
V
------
T
P
--
E
E
R
D
W
L
E
E
K
Y
P
G
W
N
K
-
R
W
G
R
C
-----------
W
D
V
I
T
E
N
V
L
N
D
R
M
D
L
--------
V
-----
S
P
E
T
L
P
S
V
C
N
M
S
Q
I
---------------------------------------
P
L
--
V
G
V
P
G
D
D
W
N
I
E
V
F
S
L
E
H
N
G
R
L
Y
H
F
G
S
E
V
D
R
W
V
F
Q
Q
--------
D
P
V
Q
Y
Q
N
H
M
N
I
V
D
R
F
L
A
G
Q
I
Q
P
M
T
L
E
G
A
L
K
Y
M
G
F
--
Q
----------
S
I
E
E
M
G
K
D
A
H
D
F
A
W
A
D
K
C
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
38.35
60%
276
- C7 -
3Q3O
-
TMOA_PSEME
A:
[344-361]
-----------------------------------------------
W
N
P
A
A
G
V
------
T
P
--
E
E
R
D
W
L
E
E
K
Y
P
G
W
N
K
-
R
W
G
R
C
-----------
W
D
V
I
T
E
N
V
L
N
D
R
M
D
L
--------
V
-----
S
P
E
T
L
P
S
V
C
N
M
S
Q
I
---------------------------------------
P
L
--
V
G
V
P
G
D
D
W
N
I
E
V
F
S
L
E
H
N
G
R
L
Y
H
F
G
S
E
V
D
R
W
V
F
Q
Q
--------
D
P
V
Q
Y
Q
N
H
M
N
I
V
D
R
F
L
A
G
Q
I
Q
P
M
T
L
E
G
A
L
K
Y
M
G
F
--
Q
----------
S
I
E
E
M
G
K
D
A
H
D
F
A
W
A
D
K
C
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
38.12
60%
291
- C7 -
3RMK
1
TMOA_PSEME
A:
[343-360]
-----------------------------------------------
W
N
P
A
A
G
V
------
T
P
--
E
E
R
D
W
L
E
E
K
Y
P
G
W
N
K
-
R
W
G
R
C
-----------
W
D
V
I
T
E
N
V
L
N
D
R
M
D
L
--------
V
-----
S
P
E
T
L
P
S
V
C
N
M
S
Q
I
---------------------------------------
P
L
--
V
G
V
P
G
D
D
W
N
I
E
V
F
S
L
E
H
N
G
R
L
Y
H
F
G
S
E
V
D
R
W
V
F
Q
Q
--------
D
P
V
Q
Y
Q
N
H
M
N
I
V
D
R
F
L
A
G
Q
I
Q
P
M
T
L
E
G
A
L
K
Y
M
G
F
--
Q
----------
S
I
E
E
M
G
K
D
A
H
D
F
A
W
A
D
K
C
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------