@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Wbm0460: (2015-12-01 )
MALNPLEQFKIHTIVELPKLFGHDINFTNSSLFMMISVVSVILFLLLGVRKGAVIPGYLQAAVEYVYDFITSIIESNTGSKGLKHIPLVFTVFTFTLSCNLVGMLPYSFTVTSHVIVTFALSMIVFTYTTIVGFKEKGINFLRILLPEGIPSWLAPMMVFIKLFAYLARPISLSIRLAANMIAGHTIIKVVAGFIMNMHLILTPIPFLFIIALIGFEVFVAILQAYIFTILTCIYLSDAVK
Atome Classification :
(20 SA)
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.........10.-------...--....20........-30---....---.....--------------------------40........50....--....60-....-----------..---..70........80-..----.......90---...------.....100......----------------.110.---.-----....--------------...120.-------------------......130.......140.......150........-----------160......-.170.----......180...--....------190.......200...------------....210-....---.--....220-----------....-----------...230.......240------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MALN
P
L
E
Q
F
K
I
H
-------
T
I
V
--
E
L
P
K
L
FGHDINFTN-
S
----
S
L
F
M
---
M
I
S
V
V
--------------------------
S
V
I
L
F
L
L
L
GVRKGAVI--
P
G
Y
L
Q
A
-
A
V
E
Y
-----------
V
Y
---
D
F
I
T
S
I
I
ESNTGS--KG----LKHI
P
L
V
F
T
---
V
F
T
------
F
T
LS
C
N
L
V
G
MLP
Y
S
----------------
F
T
--V---
T
-----
S
H
V
I
--------------
V
T
F
A
L
S
M
-------------------
I
V
F
T
Y
T
TIVGFKEKGI
N
F
L
R
I
LLPEG
I
P
-
S
W
L
A
P
M
M
V
-----------
F
I
K
L
F
A
Y
LA-RP
I
S
L
----
S
I
R
L
A
A
N
M
IA
G
H
--
T
I
I
K
------
V
V
A
G
F
I
M
N
M
H
L
I
LTP
I
------------
P
F
L
F
I
---
I
A
L
I
---
G
--
F
E
V
F
V
A
I
-----------
L
Q
A
Y
-----------
I
F
T
I
L
T
C
I
Y
L
SDAVK-------------------------------------
23
Fugue
85.16
21%
-168
- C5 -
4OGE
6
CAS9_ACTNH
A:
[10-1101]
H
H
L
R
V
G
I
D
V
G
TH
S
V
G
L
A
T
L
R
V
D
DHGTPIELL
S
A
L
S
H
I
H
DLS
G
I
A
R
R
A
R
R
L
L
H
H
R
R
T
Q
L
Q
Q
L
D
E
V
L
R
D
L
GFPIPS
M
A
V
R
H
I
A
R
H
R
GWRNPYSKVESLLSPAEESPFMKRKICARQGVSPD
V
C
K
Q
L
L
RAVFKADSPRGSAVSRVAPDPLPGQGSFRRAPKCD
P
E
F
Q
R
F
R
I
I
S
I
V
A
N
L
R
I
S
ETKG
E
N
R
P
LT
A
D
E
R
R
H
V
V
T
F
L
T
EDSQADLT
W
V
D
V
A
E
K
L
GVHRRDLRGTAVHTRSAARPPID
A
T
D
R
I
M
R
Q
TKI
S
S
L
K
T
W
W
E
E
AD
S
E
Q
R
G
A
M
I
R
Y
L
Y
EDPTD
S
E
C
A
E
I
I
AELPEEDQAKLDSLH
L
P
A
G
R
A
AYS
R
E
S
L
T
A
L
S
D
H
M
L
A
T
TDD
L
H
E
A
R
K
R
L
FGVDDS
W
A
P
P
A
E
A
INAPVGN
P
S
V
D
R
T
L
K
I
V
G
R
Y
L
S
A
V
E
S
M
WGTPE
V
I
H
V
E
H
V
R
DGFTS
E
R
M
A
D
E
R
D
K
A
N
R
R
R
Y
N
D
N
Q
E
A
M
K
K
I
Q
R
D
Y
GKEGYIS
R
G
D
I
V
R
L
D
A
L
E
L
Q
GCACLYCGTTIGYHT
C
Q
L
D
HI
V
P
Q
A
G
PGSNNRRGN
L
V
A
V
C
E
R
C
N
R
S
K
SNTP
F
A
V
W
A
Q
K
CGIPHVG
V
K
E
A
I
G
R
V
R
G
WRKQTS
S
E
D
L
T
R
L
K
K
E
V
I
A
R
L
R
RTQEDPEIDERSMESVA
W
M
A
N
E
L
H
H
R
I
A
A
A
Y
P
E
T
T
V
M
V
Y
R
GS
I
T
A
A
A
R
K
A
A
GIDSRINLIGEKGRKDRIDRR
H
H
A
V
D
A
S
V
V
A
L
ME
A
S
V
A
K
T
L
A
E
R
S
S
L
R
G
E
Q
R
L
T
GKEQTWKQYTGST
V
G
A
R
E
H
F
E
M
W
R
G
H
M
L
H
L
T
E
L
F
N
E
R
L
A
E
DKV
Y
V
T
Q
N
I
R
LRLSDGNAHT
V
N
P
S
K
L
V
S
H
RLGDGLT
V
Q
Q
I
D
R
ACT
P
A
L
W
C
A
L
T
R
EKDFDEK
N
G
L
P
A
R
E
D
R
A
I
R
-------
V
-----------
H
G
H
E
I
K
S
-
S
----
D
Y
I
Q
---
V
F
S
K
R
--------------------------
K
K
T
D
S
D
R
D
E
T
P
F
G
A
I
A
V
R
G
G
F
V
E
I
-
G
P
S
I
-----------
H
H
---
A
R
I
Y
R
V
---------
E
G
----
K
K
P
V
Y
A
M
L
R
---
V
F
T
------
H
D
L
L
S
Q
R
H
G
D
L
F
--------------------------------
S
A
V
I
--------------
P
P
Q
S
I
S
M
-------------------
R
C
A
E
------------
P
K
L
R
K
A
I
T
T
G
N
A
-
T
Y
L
G
W
V
V
V
-----------
G
D
E
L
E
I
N
V
D
-
S
F
T
K
Y
----
A
I
G
R
F
L
E
D
F
P
N
T
--
T
R
W
R
------
I
C
-
G
Y
D
T
N
S
K
L
T
L
K
P
I
VLAAEGLENPS
S
A
V
N
E
I
---
V
E
L
K
---
G
--
W
R
V
A
I
N
V
-----------
L
T
K
V
-----------
H
P
T
V
V
R
R
D
A
L
G
R
P
R
Y
SSRSN
L
P
T
S
W
T
IE------------------------
29
Fugue
79.82
18%
-141
- C4 -
4FYP
1
VSP1_ARATH
A:
[34-261]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------G
L
S
I
N
Y
P
N
C
R
S
W
H
-------
L
G
V
--
E
T
S
N
I
I
N
F
D
-------------------------------------------------------
T
V
P
A
N
C
K
A
Y
V
--
E
D
Y
L
I
T
-
S
K
Q
Y
-----------
Q
Y
---
D
S
K
T
V
N
K
E
A
Y
F
Y
A
--
K
G
----
L
A
L
K
N
D
T
V
N
---
V
W
I
------
F
D
L
D
D
T
L
L
S
S
I
P
Y
Y
----------------
A
K
--
Y
GYG
T
-----
E
N
T
A
--------------
P
G
A
Y
W
S
W
-------------------
L
E
S
G
E
S
T
--
P
G
L
P
E
T
L
H
L
Y
E
N
L
L
E
L
G
I
------
E
P
I
I
-----------
I
S
D
R
W
K
K
L
S
-
E
V
T
V
E
----
N
L
K
A
V
G
V
T
K
W
K
H
--
L
I
L
K
PNGSKL
T
Q
V
V
Y
K
S
K
V
R
N
S
L
V
K
K
------------
G
Y
-
N
I
---
V
G
N
I
---
G
DQ
W
A
D
L
V
E
D
-----------
T
P
G
R
-----------
V
F
K
L
P
N
P
L
Y
Y
V
P
S
L
E
H
H
H
H---------------------------------
26
Fugue
77.96
18%
-161
- C5 -
2E7J
3
SPSS1_ARCFU
A:
[8-371]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DFINIDPLQTGGKLT
E
E
A
R
Q
A
L
L
E
W
P
P
I
H
-------
D
F
I
H
N
Q
L
P
K
F
L
G
C
D
V
A
R
V
T
-
N
G
A
R
E
A
K
F
A
---
V
M
H
S
L
AKKD
A
W
V
V
M
D
ENCH
Y
S
S
Y
V
A
A
E
R
A
G
L
N
I
A
L
V
P
K
T
D
Y
P
D
Y
A
I
T
--
P
E
N
F
A
Q
-
T
I
E
E
-----------
T
K
KRG
E
V
V
L
A
L
I
T
Y
P
D
G
N
--
Y
G
NLPD
V
K
K
I
A
K
V
C
S
E
Y
D
V
P
L
------
L
V
N
G
A
Y
A
I
G
R
M
P
V
S
----------------
L
K
--
E
---
I
-----
G
A
D
F
--------------
I
V
G
S
G
H
K
SMAAS
G
P
I
G
V
M
G
M
K
EEWAE
I
V
L
R
R
S
E
K
Y
K
N
K
E
V
E
L
L
G
C
T
-
A
R
G
A
T
I
I
-
T
L
M
A
S
F
P
H
-----------
V
R
E
R
I
K
R
W
D
-
E
E
V
E
K
----
A
R
R
F
A
A
E
M
E
K
L
G
----
I
K
------
Q
L
G
D
N
P
H
N
H
D
L
M
F
F
H
A
------------
E
V
L
Y
E
---
I
S
K
K
AKG
G
--
R
F
F
L
Y
R
E
-----------
L
K
S
R
KIHGIKPGLTR
Y
F
K
L
S
T
Y
G
L
S
D
E
E
V
D
Y
V
L
N
A
F
K
E
I
I
E
K
Y
S-----------------------
12
HHSearch
76.22
30%
-141
- C6 -
1C17
-
ATP6_ECOLI
M:
[97-265]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
S
----
K
L
I
A
P
L
A
L
T
---
I
F
V
------
W
V
F
L
M
N
L
M
D
L
L
P
I
D
LLPYIAEHVLGLPALR
V
V
--
P
---
S
-----
A
D
V
N
--------------
V
T
L
S
M
A
L
-------------------
G
V
F
I
L
I
L
F
Y
S
I
K
M
K
---------------------------------------
S
L
L
S
-
K
P
V
S
L
----
G
L
R
L
F
G
N
M
Y
A
G
E
--
L
I
F
I
------
L
I
A
G
L
L
P
W
W
S
------------------
Q
W
I
L
N
---
V
P
W
A
---
I
--
F
H
I
L
I
I
T
-----------
L
Q
A
F
-----------
I
F
M
V
L
T
I
V
Y
L
S
-----------------------------------------
1
PsiBlast_PDB
72.65
27%
-144
- C6 -
1C17
-
ATP6_ECOLI
M:
[103-265]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
L
A
L
T
---
I
F
V
------
W
V
F
L
M
N
L
M
D
L
L
P
I
D
----------------
L
L
PY
I
---
A
-----
E
H
V
L
GLPALRVVPSADVN
V
T
L
S
M
A
L
-------------------
G
V
F
I
L
I
L
F
Y
S
I
K
M
K
---------------------------------------
S
L
L
S
-
K
P
V
S
L
----
G
L
R
L
F
G
N
M
Y
A
G
E
--
L
I
F
I
------
L
I
A
G
L
L
P
W
W
S
Q
W
I
L
N
V
------------
P
W
A
I
--------------
F
H
I
L
I
I
T
-----------
L
Q
A
F
-----------
I
F
M
V
L
T
I
V
Y
L
S
-----------------------------------------
22
Fugue
72.24
26%
-117
- C6 -
1C17
-
ATP6_ECOLI
M:
[95-265]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
G
--
K
S
----
K
L
I
A
P
L
A
L
T
---
I
F
V
------
W
V
F
L
M
N
L
M
D
L
L
P
I
D
----------------
L
L
-----------------------------------
P
Y
-------------------
I
A
E
H
V
L
G
L
P
A
L
R
V
V
P
S
A
D
V
N
V
T
L
S
M
A
L
G
-
V
F
I
L
I
L
F
Y
-----------
S
I
K
M
K
S
L
L
S
-
K
P
V
S
L
----
G
L
R
L
F
G
N
M
Y
A
G
E
--
L
I
F
I
------
L
I
A
G
L
L
P
W
W
------
S
------------
Q
W
I
L
N
---
V
P
W
A
---
I
--
F
H
I
L
I
I
T
-----------
L
Q
A
F
-----------
I
F
M
V
L
T
I
V
Y
L
S
-----------------------------------------
5
PsiBlast_PDB
69.34
23%
-104
- C6 -
3T1P
-
A1AT_HUMAN
A:
[258-373]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
K
L
Q
H
L
E
N
E
L
-----------
T
H
---
D
I
I
T
K
F
L
E
N
E
D
R
R
--
S
A
----
S
L
H
L
P
K
L
C
I
---
T
G
T
------
Y
D
L
K
S
-
V
L
G
Q
L
G
I
T
----------------
K
V
--
F
---
S
NGADL
S
G
V
T
--------------
E
E
A
P
L
K
L
-------------------
S
K
A
V
H
K
A
V
L
C
I
D
E
K
G
T
E
A
A
G
A
M
F
L
E
A
I
P
-
R
S
I
P
P
E
V
K
-----------
F
N
K
P
F
V
F
L
M
-
I
E
Q
N
T
----
K
S
P
L
F
M
G
K
V
V
N
P
--
T
Q
K
------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
69.09
23%
-94
- C6 -
3NE4
-
A1AT_HUMAN
A:
[258-373]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
K
L
Q
H
L
E
N
E
L
-----------
T
H
---
D
I
I
T
K
F
L
E
N
E
D
R
R
--
S
A
----
S
L
H
L
P
K
L
S
I
---
T
G
T
------
Y
D
L
K
S
-
V
L
G
Q
L
G
I
T
----------------
K
V
--
F
---
S
NGADL
S
G
V
T
--------------
E
E
A
P
L
K
L
-------------------
S
K
A
V
H
K
A
V
L
T
I
D
E
K
G
T
E
A
A
G
A
M
F
L
E
A
I
P
-
M
S
I
P
P
E
V
K
-----------
F
N
K
P
F
V
F
L
M
-
I
E
Q
N
T
----
K
S
P
L
F
M
G
K
V
V
N
P
--
T
Q
-------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
68.00
23%
-107
- C6 -
1OPH
-
A1AT_HUMAN
A:
[258-373]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
K
L
Q
H
L
E
N
E
L
-----------
T
H
---
D
I
I
T
K
F
L
E
N
E
D
R
R
--
S
A
----
S
L
H
L
P
K
L
S
I
---
T
G
T
------
Y
D
L
K
S
-
V
L
G
Q
L
G
I
T
----------------
K
V
--
F
---
S
NGADL
S
G
V
T
--------------
E
E
A
P
L
K
L
-------------------
S
K
A
V
H
K
A
V
L
T
I
D
E
K
G
T
E
A
A
G
A
M
F
L
E
A
I
P
-
R
S
I
P
P
E
V
K
-----------
F
N
K
P
F
V
F
L
I
-
I
E
Q
N
T
----
K
A
P
L
F
M
G
R
V
V
N
P
--
T
Q
K
------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
66.27
23%
-99
- C6 -
1PSI
1
A1AT_HUMAN
A:
[258-373]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
K
L
Q
H
L
E
N
E
L
-----------
T
H
---
D
I
I
T
K
F
L
E
N
E
D
R
R
--
S
A
----
S
L
H
L
P
K
L
S
I
---
T
G
T
------
Y
D
L
K
S
-
V
L
G
Q
L
G
I
T
----------------
K
V
--
F
---
S
NGADL
S
G
V
T
--------------
E
E
A
P
L
K
L
-------------------
S
K
A
V
H
K
A
V
L
T
I
D
E
K
G
T
E
A
A
G
A
M
F
L
E
A
I
P
-
M
S
I
P
P
E
V
K
-----------
F
N
K
P
F
V
F
L
M
-
I
E
Q
N
T
----
K
S
P
L
F
M
G
K
V
V
N
P
--
T
Q
K
------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
65.80
23%
-93
- C6 -
1QLP
-
A1AT_HUMAN
A:
[258-373]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
K
L
Q
H
L
E
N
E
L
-----------
T
H
---
D
I
I
T
K
F
L
E
N
E
D
R
R
--
S
A
----
S
L
H
L
P
K
L
S
I
---
T
G
T
------
Y
D
L
K
S
-
V
L
G
Q
L
G
I
T
----------------
K
V
--
F
---
S
NGADL
S
G
V
T
--------------
E
E
A
P
L
K
L
-------------------
S
K
A
V
H
K
A
V
L
T
I
D
E
K
G
T
E
A
A
G
A
M
F
L
E
A
I
P
-
M
S
I
P
P
E
V
K
-----------
F
N
K
P
F
V
F
L
M
-
I
E
Q
N
T
----
K
S
P
L
F
M
G
K
V
V
N
P
--
T
Q
K
------------------------------------------------------------------------------------------------------------------------------------------
24
Fugue
63.87
10%
-156
- C5 -
2H7O
-
YPKA_YERPS
A:
[439-731]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RIT
P
K
K
L
R
E
L
S
D
L
L
R
T
H
L
S
S
A
A
T
K
Q
L
D
-------
M
G
G
--
V
L
S
D
L
D
T
M
L
V
A
L
D
K
-
A
----
E
R
E
V
D
K
D
Q
L
K
S
F
--------------------------
N
S
L
I
L
K
T
Y
R
V
I
E
D
Y
V
K
--
G
N
F
M
L
S
-
I
V
E
P
-----------
S
L
---
Q
R
I
Q
K
H
L
D
Q
T
H
S
F
--
S
D
----
I
G
S
L
V
R
A
H
K
---
H
L
E
------
T
L
L
E
V
L
V
T
L
S
Q
P
V
S
----------------
S
E
--
T
---
Y
-----
G
F
L
N
--------------
R
L
A
E
A
K
I
-------------------
T
L
S
Q
Q
L
N
T
L
Q
Q
Q
Q
E
S
A
K
A
Q
L
S
I
L
I
N
R
S
G
-
S
W
A
D
V
A
R
Q
-----------
S
L
Q
R
F
D
S
T
R
-
P
V
V
K
F
GTEQ
Y
T
A
I
H
R
Q
M
M
A
A
H
A
A
I
T
L
Q
------
E
V
S
E
F
T
D
D
M
R
N
F
T
V
D
S
------------
I
P
L
L
I
----
Q
L
G
---
R
--
S
S
L
M
D
E
H
-----------
L
V
E
Q
-----------
R
E
K
L
R
E
L
T
T
I
A
E
R
L
N
R
L
E
R
E
W-------------------------------
9
PsiBlast_PDB
63.65
23%
-99
- C6 -
4PYW
2
A1AT_HUMAN
A:
[268-383]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
K
L
Q
H
L
E
N
E
L
-----------
T
H
---
D
I
I
T
K
F
L
E
N
E
D
R
R
--
S
A
----
S
L
H
L
P
K
L
S
I
---
T
G
T
------
Y
D
L
K
S
-
V
L
G
Q
L
G
I
T
----------------
K
V
--
F
---
S
NGADL
S
G
V
T
--------------------
L
-------------------
S
K
A
V
H
K
A
V
L
T
I
D
E
K
G
T
E
A
---
M
F
L
E
A
I
P
-
M
S
I
P
P
E
V
K
-----------
F
N
K
P
F
V
F
L
M
-
I
E
Q
N
T
----
K
S
P
L
F
M
G
K
V
V
N
P
--
T
Q
-------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
63.61
23%
-91
- C6 -
1OO8
-
A1AT_HUMAN
A:
[258-373]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
K
L
Q
H
L
E
N
E
L
-----------
T
H
---
D
I
I
T
K
F
L
E
N
E
D
R
R
--
S
A
----
S
L
H
L
P
K
L
S
I
---
T
G
T
------
Y
D
L
K
S
-
V
L
G
Q
L
G
I
T
----------------
K
V
--
F
---
S
NGADL
S
G
V
T
--------------
E
E
A
P
L
K
L
-------------------
S
K
A
V
H
K
A
V
L
T
I
D
E
K
G
T
E
A
A
G
A
M
F
L
E
A
I
P
-
R
S
I
P
P
E
V
K
-----------
F
N
K
P
F
V
F
L
I
-
I
E
Q
N
T
----
K
A
P
L
F
M
G
R
V
V
N
P
--
T
Q
-------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
62.40
23%
-86
- C6 -
1KCT
-
A1AT_HUMAN
A:
[258-373]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
K
L
Q
H
L
E
N
E
L
-----------
T
H
---
D
I
I
T
K
F
L
E
N
E
D
R
R
--
S
A
----
S
L
H
L
P
K
L
S
I
---
T
G
T
------
Y
D
L
K
S
-
V
L
G
Q
L
G
I
T
----------------
K
V
--
F
---
S
NGADL
S
G
V
T
--------------
E
E
A
P
L
K
L
-------------------
S
K
A
V
H
K
A
V
L
T
I
D
E
K
G
T
E
A
A
G
A
M
F
L
E
A
I
P
-
M
S
I
P
P
E
V
K
-----------
F
N
K
P
F
V
F
L
M
-
I
E
Q
N
T
----
K
S
P
L
F
M
G
K
V
V
N
P
--
T
Q
K
------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
60.37
23%
-84
- C6 -
1ATU
-
A1AT_HUMAN
A:
[258-373]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
K
L
Q
H
L
E
N
E
L
-----------
T
H
---
D
I
I
T
K
F
L
E
N
E
D
R
R
--
S
A
----
S
L
H
L
P
K
L
S
I
---
T
G
T
------
Y
D
L
K
S
-
V
L
G
Q
L
G
I
T
----------------
K
V
--
F
---
S
NGADL
S
G
V
T
--------------
E
E
A
P
L
K
L
-------------------
S
K
A
V
H
K
A
V
L
T
I
D
E
K
G
T
E
A
A
G
A
M
F
L
E
A
I
P
-
M
S
I
P
P
E
V
K
-----------
F
N
K
P
F
V
F
L
I
-
I
E
Q
N
T
----
K
A
P
L
F
M
G
R
V
V
N
P
--
T
Q
K
------------------------------------------------------------------------------------------------------------------------------------------
31
Fugue
58.52
13%
-165
- C3 -
2PNW
1
?
A:
[7-371]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------F
S
I
D
E
V
S
FRDLPGWGQDDP
R
K
L
F
P
A
M
A
T
I
L
S
H
L
R
N
A
K
P
Y
RTGALGI
T
A
A
--
E
L
V
S
L
L
E
L
A
E
R
G
Q
V
-
N
----
S
P
E
Q
---
A
R
Q
F
F
--------------------------
E
T
N
-
S
V
P
F
R
I
S
P
S
G
F
V
--
T
A
F
Y
E
P
-
E
L
E
V
S
ATPDDVWR
Y
P
I
Y
---
R
R
P
P
E
L
V
D
I
D
N
D
N
RP
D
G
----
F
D
P
S
Y
A
F
G
K
---
A
D
E
EGISYF
P
D
R
R
A
I
D
E
G
C
L
R
G
R
----------------
G
L
--
E
---
I
-----
A
W
A
R
--------------
S
K
V
D
L
F
F
-------------------
V
H
V
Q
G
A
A
R
L
V
F
P
D
G
A
I
K
R
I
T
Y
A
A
K
A
G
H
V
F
S
P
I
G
R
L
L
L
D
R
GELDPKTIS
M
Q
T
I
R
Q
W
L
A
D
H
P
D
E
V
----
D
G
V
L
W
H
N
--
R
S
Y
--
I
F
F
R
------
E
A
-
G
P
I
A
A
A
K
V
P
L
V
A
G
------------
R
A
L
A
V
DRL
I
H
T
F
---
G
--
L
P
F
F
I
H
A
PTLTHLDDGK
P
F
A
R
L
-----------
M
L
A
L
D
T
G
S
A
I
V
G
P
A
R
G
D
I
F
TGSG
F
E
A
G
E
L
A
GT
V
R
N
E
A
D
F
Y
I
L
L
P
R
I
A
A
E
R
Y
R
2
PsiBlast_PDB
53.14
27%
-86
- C6 -
4FYP
1
VSP1_ARATH
A:
[34-120]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
L
S
I
N
Y
P
N
C
R
----
S
W
H
L
---
G
V
E
T
S
--------------------------
N
I
I
N
F
D
T
V
P
A
N
C
K
A
Y
V
--
E
D
Y
L
I
T
-
S
K
Q
Y
-----------
Q
Y
---
D
S
K
T
V
N
K
E
A
Y
F
Y
A
--
K
G
----
L
A
L
K
N
D
T
V
N
---
V
W
I
------
F
D
L
D
D
T
L
L
S
S
I
P
Y
Y
----------------
A
K
--
Y
---
G
-----
Y
G
T
E
--------------
N
T
A
P
G
A
Y
-------------------
W
S
W
L
E
S
G
E
S
T
P
G
L
P
E
T
L
H
L
Y
E
N
L
L
E
L
G
I
-
E
P
I
I
I
S
D
R
-----------
W
K
K
L
S
E
V
T
V
-
E
N
L
K
A
----
V
G
V
T
K
W
K
H
L
I
L
K
--
P
N
G
S
------
K
L
T
Q
V
V
Y
K
S
K
V
R
N
S
L
V
------------
K
K
G
Y
N
---
I
V
G
N
---
I
--
G
D
Q
W
A
D
L
-----------
V
E
D
T
-----------
P
G
R
V
F
K
L
P
N
P
L
Y
Y
V
P
-------------------------------------
21
HHSearch
41.18
14%
155
- C6 -
2LYY
-
?
A:
[60-87]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
K
K
Q
E
-
M
M
D
Y
-----------
Y
M
---
D
R
Y
K
E
M
L
D
A
N
M
E
D
--
Y
I
----
E
N
F
D
H
Y
R
A
T
---
Q
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
HHSearch
26.34
13%
284
- C6 -
1N7L
-
PPLA_RABIT
A:
[23-37]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
Q
A
R
Q
N
-
L
Q
N
L
-----------
F
I
---
N
F
A
L
I
L
I
F
L
L
L
I
A
--
I
I
----
V
M
L
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------