@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Wbm0520: (2015-12-02 )
MNIHEYQAKEILHKFNVPVPKGFVAMSAEEAETKINQLKSDVLVVKAQIHAGGRGKAGGVKLAKSAEEAQQFVKGMLGITLVTHQTGPNGQQVRRVYIEEGSSIKKEYYLSIVIDPKLSRPAFIFSSEGGMDIEEVAKNFPTKIVKLDIDYAADFASFDSRKLSNIFNLSPEQIEKITNVAKNIYDTFIATDANQIEINPLVETNSGDFIALDAKISFDDNALYRHPEIVELRDYDEEVKEEIEASKHGLSYIKMDGNIGCMVNGAGLAMATMDIIKYYGAEPANFLDVGGGASKETVTEAFKIILSDSNVKGILVNIFGGIMRCDIIASGIVEAAKGMSIKVPLVVRLSGTNFEKGKRILEESGLNIIAADELDEAAQKIVKEVE
Atome Classification :
(23 SA)
.........10........20........30........-40.-.......50.....-------.-------..60........70........80........90........100.......110.......120.......130.......140.......150.......160..-.....170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380....
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MN
I
H
E
Y
Q
A
K
E
I
L
H
K
FNVPVPKG
F
V
AM
S
A
E
E
A
E
T
K
I
N
Q
LK-S
D
V
-
L
V
V
K
A
Q
I
HAGGRGK-------A-------G
G
V
K
L
A
K
S
A
E
E
A
Q
Q
F
V
K
G
ML
G
I
T
L
V
T
HQTGP
N
G
Q
Q
V
R
R
V
Y
IEEGSSI
K
K
E
Y
Y
L
S
I
V
IDPKLSR
P
A
F
I
F
SSEGGM
D
I
E
E
V
A
K
NFPT
K
I
V
K
L
D
I
DYAA
D
F
ASF
D
S
R
K
L
S
-
N
I
FNL
S
P
E
Q
I
E
K
I
T
N
V
A
K
N
I
Y
D
T
F
IATDA
N
Q
I
E
I
N
P
L
V
ETNSG
D
F
I
A
L
D
A
K
I
SFDDNALYRHP
E
I
V
ELRDY
D
E
E
V
K
E
E
I
E
A
S
KHG
L
S
Y
I
K
MDGN
I
G
C
M
VNGA
G
L
A
M
A
T
M
D
I
I
K
Y
YGAEPA
N
F
L
DVGGGA
S
K
E
T
V
T
E
A
F
K
I
ILSDSNV
K
G
I
L
V
N
I
F
G
G
I
M
R
C
D
I
I
A
S
G
I
V
E
A
AKG
M
S
I
K
V
P
L
V
V
R
LSGT
N
F
E
K
G
K
R
I
L
E
ESG
L
N
I
I
A
A
D
E
L
D
E
A
A
Q
K
I
V
K
EVE
3
PsiBlast_PDB
92.83
49%
-100
- C3 -
1JKJ
5
SUCC_ECOLI
B:
[1-386]
M
N
L
H
E
Y
Q
A
K
Q
L
F
A
R
Y
G
L
P
A
P
V
G
Y
A
C
T
T
P
R
E
A
E
E
A
A
S
K
I
G
-
A
G
P
-
W
V
V
K
C
Q
V
H
A
G
G
R
G
K
-------
A
-------
G
G
V
K
V
V
N
S
K
E
D
I
R
A
F
A
E
N
W
L
G
K
R
L
V
T
Y
Q
T
D
A
N
G
Q
P
V
N
Q
I
L
V
E
A
A
T
D
I
A
K
E
L
Y
L
G
A
V
V
D
R
S
S
R
R
V
V
F
M
A
S
T
E
G
G
V
E
I
E
K
V
A
E
E
T
P
H
L
I
H
K
V
A
L
D
P
L
T
G
P
M
P
Y
Q
G
R
E
L
A
-
F
K
L
G
L
E
G
K
L
V
Q
Q
F
T
K
I
F
M
G
L
A
T
I
F
L
E
R
D
L
A
L
I
E
I
N
P
L
V
I
T
K
Q
G
D
L
I
C
L
D
G
K
L
G
A
D
G
N
A
L
F
R
Q
P
D
L
R
E
M
R
D
Q
S
Q
E
D
P
R
E
A
Q
A
A
Q
W
E
L
N
Y
V
A
L
D
G
N
I
G
C
M
V
N
G
A
G
L
A
M
G
T
M
D
I
V
K
L
H
G
G
E
P
A
N
F
L
D
V
G
G
G
A
T
K
E
R
V
T
E
A
F
K
I
I
L
S
D
D
K
V
K
A
V
L
V
N
I
F
G
G
I
V
R
C
D
L
I
A
D
G
I
I
G
A
V
A
E
V
G
V
N
V
P
V
V
V
R
L
E
G
N
N
A
E
L
G
A
K
K
L
A
D
S
G
L
N
I
I
A
A
K
G
L
T
D
A
A
Q
Q
V
V
A
A
V
E
4
PsiBlast_PDB
92.57
49%
-102
- C3 -
2NU6
6
SUCC_ECOLI
B:
[1-386]
M
N
L
H
E
Y
Q
A
K
Q
L
F
A
R
Y
G
L
P
A
P
V
G
Y
A
C
T
T
P
R
E
A
E
E
A
A
S
K
I
G
-
A
G
P
-
W
V
V
K
C
Q
V
H
A
G
G
R
G
K
-------
A
-------
G
G
V
K
V
V
N
S
K
E
D
I
R
A
F
A
E
N
W
L
G
K
R
L
V
T
Y
Q
T
D
A
N
G
Q
P
V
N
Q
I
L
V
E
A
A
T
D
I
A
K
E
L
Y
L
G
A
V
V
D
R
S
S
R
R
V
V
F
M
A
S
T
E
G
G
V
E
I
E
K
V
A
E
E
T
P
H
L
I
H
K
V
A
L
D
P
L
T
G
P
M
P
Y
Q
G
R
E
L
A
-
F
K
L
G
L
E
G
K
L
V
Q
Q
F
T
K
I
F
M
G
L
A
T
I
F
L
E
R
D
L
A
L
I
E
I
N
P
L
V
I
T
K
Q
G
D
L
I
C
L
D
G
K
L
G
A
D
G
N
A
L
F
R
Q
P
D
L
R
E
M
R
D
Q
S
Q
E
D
P
R
E
A
Q
A
A
Q
W
E
L
N
Y
V
A
L
D
G
N
I
G
C
M
V
N
G
A
G
L
A
M
G
T
M
D
I
V
K
L
H
G
G
E
P
A
N
F
L
D
V
G
G
G
A
T
K
E
R
V
T
E
A
F
K
I
I
L
S
D
D
K
V
K
A
V
L
V
N
I
F
G
G
I
V
R
C
D
L
I
A
D
G
I
I
G
A
V
A
E
V
G
V
N
V
P
V
V
V
R
L
E
G
N
N
A
E
L
G
A
K
K
L
A
D
S
G
L
N
I
I
A
A
K
G
L
T
D
A
A
Q
Q
V
V
A
A
V
E
5
PsiBlast_PDB
92.51
49%
-100
- C3 -
2NU7
7
SUCC_ECOLI
B:
[1-386]
M
N
L
H
E
Y
Q
A
K
Q
L
F
A
R
Y
G
L
P
A
P
V
G
Y
A
C
T
T
P
R
E
A
E
E
A
A
S
K
I
G
-
A
G
P
-
W
V
V
K
C
Q
V
H
A
G
G
R
G
K
-------
A
-------
G
G
V
K
V
V
N
S
K
E
D
I
R
A
F
A
E
N
W
L
G
K
R
L
V
T
Y
Q
T
D
A
N
G
Q
P
V
N
Q
I
L
V
E
A
A
T
D
I
A
K
E
L
Y
L
G
A
V
V
D
R
S
S
R
R
V
V
F
M
A
S
T
E
G
G
V
E
I
E
K
V
A
E
E
T
P
H
L
I
H
K
V
A
L
D
P
L
T
G
P
M
P
Y
Q
G
R
E
L
A
-
F
K
L
G
L
E
G
K
L
V
Q
Q
F
T
K
I
F
M
G
L
A
T
I
F
L
E
R
D
L
A
L
I
E
I
N
P
L
V
I
T
K
Q
G
D
L
I
C
L
D
G
K
L
G
A
D
G
N
A
L
F
R
Q
P
D
L
R
E
M
R
D
Q
S
Q
E
D
P
R
E
A
Q
A
A
Q
W
E
L
N
Y
V
A
L
D
G
N
I
G
C
M
V
N
G
A
G
L
A
M
G
T
M
D
I
V
K
L
H
G
G
E
P
A
N
F
L
D
V
G
G
G
A
T
K
E
R
V
T
E
A
F
K
I
I
L
S
D
D
K
V
K
A
V
L
V
N
I
F
G
G
I
V
R
C
D
L
I
A
D
G
I
I
G
A
V
A
E
V
G
V
N
V
P
V
V
V
R
L
E
G
N
N
A
E
L
G
A
K
K
L
A
D
S
G
L
N
I
I
A
A
K
G
L
T
D
A
A
Q
Q
V
V
A
A
V
E
2
PsiBlast_PDB
92.22
49%
-102
- C3 -
2SCU
2
SUCC_ECOLI
B:
[1-385]
M
N
L
H
E
Y
Q
A
K
Q
L
F
A
R
Y
G
L
P
A
P
V
G
Y
A
C
T
T
P
R
E
A
E
E
A
A
S
K
I
G
-
A
G
P
-
W
V
V
K
C
Q
V
H
A
G
G
R
G
K
-------
A
-------
G
G
V
K
V
V
N
S
K
E
D
I
R
A
F
A
E
N
W
L
G
K
R
L
V
T
Y
Q
T
D
A
N
G
Q
P
V
N
Q
I
L
V
E
A
A
T
D
I
A
K
E
L
Y
L
G
A
V
V
D
R
S
S
R
R
V
V
F
M
A
S
T
E
G
G
V
E
I
E
K
V
A
E
E
T
P
H
L
I
H
K
V
A
L
D
P
L
T
G
P
M
P
Y
Q
G
R
E
L
A
-
F
K
L
G
L
E
G
K
L
V
Q
Q
F
T
K
I
F
M
G
L
A
T
I
F
L
E
R
D
L
A
L
I
E
I
N
P
L
V
I
T
K
Q
G
D
L
I
C
L
D
G
K
L
G
A
D
G
N
A
L
F
R
Q
P
D
L
R
E
M
R
D
Q
S
Q
E
D
P
R
E
A
Q
A
A
Q
W
E
L
N
Y
V
A
L
D
G
N
I
G
C
M
V
N
G
A
G
L
A
M
G
T
M
D
I
V
K
L
H
G
G
E
P
A
N
F
L
D
V
G
G
G
A
T
K
E
R
V
T
E
A
F
K
I
I
L
S
D
D
K
V
K
A
V
L
V
N
I
F
G
G
I
V
R
C
D
L
I
A
D
G
I
I
G
A
V
A
E
V
G
V
N
V
P
V
V
V
R
L
E
G
N
N
A
E
L
G
A
K
K
L
A
D
S
G
L
N
I
I
A
A
K
G
L
T
D
A
A
Q
Q
V
V
A
A
V
-
61
Fugue
92.14
48%
-102
- C3 -
2SCU
2
SUCC_ECOLI
B:
[1-385]
M
N
L
H
E
Y
Q
A
K
Q
L
F
A
R
Y
G
L
P
A
P
V
G
Y
A
C
T
T
P
R
E
A
E
E
A
A
S
K
I
G
-
A
G
P
-
W
V
V
K
C
Q
V
H
A
G
G
R
G
K
A--------------
G
G
V
K
V
V
N
S
K
E
D
I
R
A
F
A
E
N
W
L
G
K
R
L
V
T
Y
Q
T
D
A
N
G
Q
P
V
N
Q
I
L
V
E
A
A
T
D
I
A
K
E
L
Y
L
G
A
V
V
D
R
S
S
R
R
V
V
F
M
A
S
T
E
G
G
V
E
I
E
K
V
A
E
E
T
P
H
L
I
H
K
V
A
L
D
P
L
T
G
P
M
P
Y
Q
G
R
E
L
A
-
F
K
L
G
L
E
G
K
L
V
Q
Q
F
T
K
I
F
M
G
L
A
T
I
F
L
E
R
D
L
A
L
I
E
I
N
P
L
V
I
T
K
Q
G
D
L
I
C
L
D
G
K
L
G
A
D
G
N
A
L
F
R
Q
P
D
L
R
E
M
R
D
Q
S
Q
E
D
P
R
E
A
Q
A
A
Q
W
E
L
N
Y
V
A
L
D
G
N
I
G
C
M
V
N
G
A
G
L
A
M
G
T
M
D
I
V
K
L
H
G
G
E
P
A
N
F
L
D
V
G
G
G
A
T
K
E
R
V
T
E
A
F
K
I
I
L
S
D
D
K
V
K
A
V
L
V
N
I
F
G
G
I
V
R
C
D
L
I
A
D
G
I
I
G
A
V
A
E
V
G
V
N
V
P
V
V
V
R
L
E
G
N
N
A
E
L
G
A
K
K
L
A
D
S
G
L
N
I
I
A
A
K
G
L
T
D
A
A
Q
Q
V
V
A
A
V
-
27
PsiBlast_CBE
91.76
49%
-100
- C3 -
2NU7
7
SUCC_ECOLI
E:
[1-385]
M
N
L
H
E
Y
Q
A
K
Q
L
F
A
R
Y
G
L
P
A
P
V
G
Y
A
C
T
T
P
R
E
A
E
E
A
A
S
K
I
G
-
A
G
P
-
W
V
V
K
C
Q
V
H
A
G
G
R
G
K
-------
A
-------
G
G
V
K
V
V
N
S
K
E
D
I
R
A
F
A
E
N
W
L
G
K
R
L
V
T
Y
Q
T
D
A
N
G
Q
P
V
N
Q
I
L
V
E
A
A
T
D
I
A
K
E
L
Y
L
G
A
V
V
D
R
S
S
R
R
V
V
F
M
A
S
T
E
G
G
V
E
I
E
K
V
A
E
E
T
P
H
L
I
H
K
V
A
L
D
P
L
T
G
P
M
P
Y
Q
G
R
E
L
A
-
F
K
L
G
L
E
G
K
L
V
Q
Q
F
T
K
I
F
M
G
L
A
T
I
F
L
E
R
D
L
A
L
I
E
I
N
P
L
V
I
T
K
Q
G
D
L
I
C
L
D
G
K
L
G
A
D
G
N
A
L
F
R
Q
P
D
L
R
E
M
R
D
Q
S
Q
E
D
P
R
E
A
Q
A
A
Q
W
E
L
N
Y
V
A
L
D
G
N
I
G
C
M
V
N
G
A
G
L
A
M
G
T
M
D
I
V
K
L
H
G
G
E
P
A
N
F
L
D
V
G
G
G
A
T
K
E
R
V
T
E
A
F
K
I
I
L
S
D
D
K
V
K
A
V
L
V
N
I
F
G
G
I
V
R
C
D
L
I
A
D
G
I
I
G
A
V
A
E
V
G
V
N
V
P
V
V
V
R
L
E
G
N
N
A
E
L
G
A
K
K
L
A
D
S
G
L
N
I
I
A
A
K
G
L
T
D
A
A
Q
Q
V
V
A
A
V
-
21
PsiBlast_CBE
91.62
49%
-104
- C3 -
2SCU
2
SUCC_ECOLI
E:
[1-385]
M
N
L
H
E
Y
Q
A
K
Q
L
F
A
R
Y
G
L
P
A
P
V
G
Y
A
C
T
T
P
R
E
A
E
E
A
A
S
K
I
G
-
A
G
P
-
W
V
V
K
C
Q
V
H
A
G
G
R
G
K
-------
A
-------
G
G
V
K
V
V
N
S
K
E
D
I
R
A
F
A
E
N
W
L
G
K
R
L
V
T
Y
Q
T
D
A
N
G
Q
P
V
N
Q
I
L
V
E
A
A
T
D
I
A
K
E
L
Y
L
G
A
V
V
D
R
S
S
R
R
V
V
F
M
A
S
T
E
G
G
V
E
I
E
K
V
A
E
E
T
P
H
L
I
H
K
V
A
L
D
P
L
T
G
P
M
P
Y
Q
G
R
E
L
A
-
F
K
L
G
L
E
G
K
L
V
Q
Q
F
T
K
I
F
M
G
L
A
T
I
F
L
E
R
D
L
A
L
I
E
I
N
P
L
V
I
T
K
Q
G
D
L
I
C
L
D
G
K
L
G
A
D
G
N
A
L
F
R
Q
P
D
L
R
E
M
R
D
Q
S
Q
E
D
P
R
E
A
Q
A
A
Q
W
E
L
N
Y
V
A
L
D
G
N
I
G
C
M
V
N
G
A
G
L
A
M
G
T
M
D
I
V
K
L
H
G
G
E
P
A
N
F
L
D
V
G
G
G
A
T
K
E
R
V
T
E
A
F
K
I
I
L
S
D
D
K
V
K
A
V
L
V
N
I
F
G
G
I
V
R
C
D
L
I
A
D
G
I
I
G
A
V
A
E
V
G
V
N
V
P
V
V
V
R
L
E
G
N
N
A
E
L
G
A
K
K
L
A
D
S
G
L
N
I
I
A
A
K
G
L
T
D
A
A
Q
Q
V
V
A
A
V
-
6
PsiBlast_PDB
91.61
49%
-98
- C3 -
2NU8
5
SUCC_ECOLI
B:
[1-386]
M
N
L
H
E
Y
Q
A
K
Q
L
F
A
R
Y
G
L
P
A
P
V
G
Y
A
C
T
T
P
R
E
A
E
E
A
A
S
K
I
G
-
A
G
P
-
W
V
V
K
C
Q
V
H
A
G
G
R
G
K
-------
A
-------
G
G
V
K
V
V
N
S
K
E
D
I
R
A
F
A
E
N
W
L
G
K
R
L
V
T
Y
Q
T
D
A
N
G
Q
P
V
N
Q
I
L
V
E
A
A
T
D
I
A
K
E
L
Y
L
G
A
V
V
D
R
S
S
R
R
V
V
F
M
A
S
T
E
G
G
V
E
I
E
K
V
A
E
E
T
P
H
L
I
H
K
V
A
L
D
P
L
T
G
P
M
P
Y
Q
G
R
E
L
A
-
F
K
L
G
L
E
G
K
L
V
Q
Q
F
T
K
I
F
M
G
L
A
T
I
F
L
E
R
D
L
A
L
I
E
I
N
P
L
V
I
T
K
Q
G
D
L
I
C
L
D
G
K
L
G
A
D
G
N
A
L
F
R
Q
P
D
L
R
E
M
R
D
Q
S
Q
E
D
P
R
E
A
Q
A
A
Q
W
E
L
N
Y
V
A
L
D
G
N
I
G
C
M
V
N
G
A
G
L
A
M
G
T
M
D
I
V
K
L
H
G
G
E
P
A
N
F
L
D
V
G
G
G
A
T
K
E
R
V
T
E
A
F
K
I
I
L
S
D
D
K
V
K
A
V
L
V
N
I
F
G
G
I
V
R
C
D
L
I
A
D
G
I
I
G
A
V
A
E
V
G
V
N
V
P
V
V
V
R
L
E
G
N
N
A
E
L
G
A
K
K
L
A
D
S
G
L
N
I
I
A
A
K
G
L
T
D
A
A
Q
Q
V
V
A
A
V
E
38
HHSearch
91.38
49%
-99
- C3 -
2NU8
5
SUCC_ECOLI
B:
[1-386]
M
N
L
H
E
Y
Q
A
K
Q
L
F
A
R
Y
G
L
P
A
P
V
G
Y
A
C
T
T
P
R
E
A
E
E
A
A
S
K
I
G
A
G
-
P
-
W
V
V
K
C
Q
V
H
A
G
G
R
G
K
-------
A
-------
G
G
V
K
V
V
N
S
K
E
D
I
R
A
F
A
E
N
W
L
G
K
R
L
V
T
Y
Q
T
D
A
N
G
Q
P
V
N
Q
I
L
V
E
A
A
T
D
I
A
K
E
L
Y
L
G
A
V
V
D
R
S
S
R
R
V
V
F
M
A
S
T
E
G
G
V
E
I
E
K
V
A
E
E
T
P
H
L
I
H
K
V
A
L
D
P
L
T
G
P
M
P
Y
Q
G
R
E
L
A
-
F
K
L
G
L
E
G
K
L
V
Q
Q
F
T
K
I
F
M
G
L
A
T
I
F
L
E
R
D
L
A
L
I
E
I
N
P
L
V
I
T
K
Q
G
D
L
I
C
L
D
G
K
L
G
A
D
G
N
A
L
F
R
Q
P
D
L
R
E
M
R
D
Q
S
Q
E
D
P
R
E
A
Q
A
A
Q
W
E
L
N
Y
V
A
L
D
G
N
I
G
C
M
V
N
G
A
G
L
A
M
G
T
M
D
I
V
K
L
H
G
G
E
P
A
N
F
L
D
V
G
G
G
A
T
K
E
R
V
T
E
A
F
K
I
I
L
S
D
D
K
V
K
A
V
L
V
N
I
F
G
G
I
V
R
C
D
L
I
A
D
G
I
I
G
A
V
A
E
V
G
V
N
V
P
V
V
V
R
L
E
G
N
N
A
E
L
G
A
K
K
L
A
D
S
G
L
N
I
I
A
A
K
G
L
T
D
A
A
Q
Q
V
V
A
A
V
E
23
PsiBlast_CBE
91.37
49%
-99
- C3 -
2NU9
4
SUCC_ECOLI
I:
[1-385]
M
N
L
H
E
Y
Q
A
K
Q
L
F
A
R
Y
G
L
P
A
P
V
G
Y
A
C
T
T
P
R
E
A
E
E
A
A
S
K
I
G
-
A
G
P
-
W
V
V
K
C
Q
V
H
A
G
G
R
G
K
-------
A
-------
G
G
V
K
V
V
N
S
K
E
D
I
R
A
F
A
E
N
W
L
G
K
R
L
V
T
Y
Q
T
D
A
N
G
Q
P
V
N
Q
I
L
V
E
A
A
T
D
I
A
K
E
L
Y
L
G
A
V
V
D
R
S
S
R
R
V
V
F
M
A
S
T
E
G
G
V
E
I
E
K
V
A
E
E
T
P
H
L
I
H
K
V
A
L
D
P
L
T
G
P
M
P
Y
Q
G
R
E
L
A
-
F
K
L
G
L
E
G
K
L
V
Q
Q
F
T
K
I
F
M
G
L
A
T
I
F
L
E
R
D
L
A
L
I
E
I
N
P
L
V
I
T
K
Q
G
D
L
I
C
L
D
G
K
L
G
A
D
G
N
A
L
F
R
Q
P
D
L
R
E
M
R
D
Q
S
Q
E
D
P
R
E
A
Q
A
A
Q
W
E
L
N
Y
V
A
L
D
G
N
I
G
C
M
V
N
G
A
G
L
A
M
G
T
M
D
I
V
K
L
H
G
G
E
P
A
N
F
L
D
V
G
G
G
A
T
K
E
R
V
T
E
A
F
K
I
I
L
S
D
D
K
V
K
A
V
L
V
N
I
F
G
G
I
V
R
C
D
L
I
A
D
G
I
I
G
A
V
A
E
V
G
V
N
V
P
V
V
V
R
L
E
G
N
N
A
E
L
G
A
K
K
L
A
D
S
G
L
N
I
I
A
A
K
G
L
T
D
A
A
Q
Q
V
V
A
A
V
-
25
PsiBlast_CBE
91.36
49%
-99
- C3 -
2NU9
4
SUCC_ECOLI
E:
[1-385]
M
N
L
H
E
Y
Q
A
K
Q
L
F
A
R
Y
G
L
P
A
P
V
G
Y
A
C
T
T
P
R
E
A
E
E
A
A
S
K
I
G
-
A
G
P
-
W
V
V
K
C
Q
V
H
A
G
G
R
G
K
-------
A
-------
G
G
V
K
V
V
N
S
K
E
D
I
R
A
F
A
E
N
W
L
G
K
R
L
V
T
Y
Q
T
D
A
N
G
Q
P
V
N
Q
I
L
V
E
A
A
T
D
I
A
K
E
L
Y
L
G
A
V
V
D
R
S
S
R
R
V
V
F
M
A
S
T
E
G
G
V
E
I
E
K
V
A
E
E
T
P
H
L
I
H
K
V
A
L
D
P
L
T
G
P
M
P
Y
Q
G
R
E
L
A
-
F
K
L
G
L
E
G
K
L
V
Q
Q
F
T
K
I
F
M
G
L
A
T
I
F
L
E
R
D
L
A
L
I
E
I
N
P
L
V
I
T
K
Q
G
D
L
I
C
L
D
G
K
L
G
A
D
G
N
A
L
F
R
Q
P
D
L
R
E
M
R
D
Q
S
Q
E
D
P
R
E
A
Q
A
A
Q
W
E
L
N
Y
V
A
L
D
G
N
I
G
C
M
V
N
G
A
G
L
A
M
G
T
M
D
I
V
K
L
H
G
G
E
P
A
N
F
L
D
V
G
G
G
A
T
K
E
R
V
T
E
A
F
K
I
I
L
S
D
D
K
V
K
A
V
L
V
N
I
F
G
G
I
V
R
C
D
L
I
A
D
G
I
I
G
A
V
A
E
V
G
V
N
V
P
V
V
V
R
L
E
G
N
N
A
E
L
G
A
K
K
L
A
D
S
G
L
N
I
I
A
A
K
G
L
T
D
A
A
Q
Q
V
V
A
A
V
-
26
PsiBlast_CBE
91.31
49%
-98
- C3 -
2NU8
5
SUCC_ECOLI
E:
[1-385]
M
N
L
H
E
Y
Q
A
K
Q
L
F
A
R
Y
G
L
P
A
P
V
G
Y
A
C
T
T
P
R
E
A
E
E
A
A
S
K
I
G
-
A
G
P
-
W
V
V
K
C
Q
V
H
A
G
G
R
G
K
-------
A
-------
G
G
V
K
V
V
N
S
K
E
D
I
R
A
F
A
E
N
W
L
G
K
R
L
V
T
Y
Q
T
D
A
N
G
Q
P
V
N
Q
I
L
V
E
A
A
T
D
I
A
K
E
L
Y
L
G
A
V
V
D
R
S
S
R
R
V
V
F
M
A
S
T
E
G
G
V
E
I
E
K
V
A
E
E
T
P
H
L
I
H
K
V
A
L
D
P
L
T
G
P
M
P
Y
Q
G
R
E
L
A
-
F
K
L
G
L
E
G
K
L
V
Q
Q
F
T
K
I
F
M
G
L
A
T
I
F
L
E
R
D
L
A
L
I
E
I
N
P
L
V
I
T
K
Q
G
D
L
I
C
L
D
G
K
L
G
A
D
G
N
A
L
F
R
Q
P
D
L
R
E
M
R
D
Q
S
Q
E
D
P
R
E
A
Q
A
A
Q
W
E
L
N
Y
V
A
L
D
G
N
I
G
C
M
V
N
G
A
G
L
A
M
G
T
M
D
I
V
K
L
H
G
G
E
P
A
N
F
L
D
V
G
G
G
A
T
K
E
R
V
T
E
A
F
K
I
I
L
S
D
D
K
V
K
A
V
L
V
N
I
F
G
G
I
V
R
C
D
L
I
A
D
G
I
I
G
A
V
A
E
V
G
V
N
V
P
V
V
V
R
L
E
G
N
N
A
E
L
G
A
K
K
L
A
D
S
G
L
N
I
I
A
A
K
G
L
T
D
A
A
Q
Q
V
V
A
A
V
-
30
PsiBlast_CBE
91.30
49%
-97
- C3 -
1JKJ
4
SUCC_ECOLI
E:
[1-385]
M
N
L
H
E
Y
Q
A
K
Q
L
F
A
R
Y
G
L
P
A
P
V
G
Y
A
C
T
T
P
R
E
A
E
E
A
A
S
K
I
G
-
A
G
P
-
W
V
V
K
C
Q
V
H
A
G
G
R
G
K
-------
A
-------
G
G
V
K
V
V
N
S
K
E
D
I
R
A
F
A
E
N
W
L
G
K
R
L
V
T
Y
Q
T
D
A
N
G
Q
P
V
N
Q
I
L
V
E
A
A
T
D
I
A
K
E
L
Y
L
G
A
V
V
D
R
S
S
R
R
V
V
F
M
A
S
T
E
G
G
V
E
I
E
K
V
A
E
E
T
P
H
L
I
H
K
V
A
L
D
P
L
T
G
P
M
P
Y
Q
G
R
E
L
A
-
F
K
L
G
L
E
G
K
L
V
Q
Q
F
T
K
I
F
M
G
L
A
T
I
F
L
E
R
D
L
A
L
I
E
I
N
P
L
V
I
T
K
Q
G
D
L
I
C
L
D
G
K
L
G
A
D
G
N
A
L
F
R
Q
P
D
L
R
E
M
R
D
Q
S
Q
E
D
P
R
E
A
Q
A
A
Q
W
E
L
N
Y
V
A
L
D
G
N
I
G
C
M
V
N
G
A
G
L
A
M
G
T
M
D
I
V
K
L
H
G
G
E
P
A
N
F
L
D
V
G
G
G
A
T
K
E
R
V
T
E
A
F
K
I
I
L
S
D
D
K
V
K
A
V
L
V
N
I
F
G
G
I
V
R
C
D
L
I
A
D
G
I
I
G
A
V
A
E
V
G
V
N
V
P
V
V
V
R
L
E
G
N
N
A
E
L
G
A
K
K
L
A
D
S
G
L
N
I
I
A
A
K
G
L
T
D
A
A
Q
Q
V
V
A
A
V
-
7
PsiBlast_PDB
91.30
49%
-99
- C3 -
2NU9
4
SUCC_ECOLI
B:
[1-385]
M
N
L
H
E
Y
Q
A
K
Q
L
F
A
R
Y
G
L
P
A
P
V
G
Y
A
C
T
T
P
R
E
A
E
E
A
A
S
K
I
G
-
A
G
P
-
W
V
V
K
C
Q
V
H
A
G
G
R
G
K
-------
A
-------
G
G
V
K
V
V
N
S
K
E
D
I
R
A
F
A
E
N
W
L
G
K
R
L
V
T
Y
Q
T
D
A
N
G
Q
P
V
N
Q
I
L
V
E
A
A
T
D
I
A
K
E
L
Y
L
G
A
V
V
D
R
S
S
R
R
V
V
F
M
A
S
T
E
G
G
V
E
I
E
K
V
A
E
E
T
P
H
L
I
H
K
V
A
L
D
P
L
T
G
P
M
P
Y
Q
G
R
E
L
A
-
F
K
L
G
L
E
G
K
L
V
Q
Q
F
T
K
I
F
M
G
L
A
T
I
F
L
E
R
D
L
A
L
I
E
I
N
P
L
V
I
T
K
Q
G
D
L
I
C
L
D
G
K
L
G
A
D
G
N
A
L
F
R
Q
P
D
L
R
E
M
R
D
Q
S
Q
E
D
P
R
E
A
Q
A
A
Q
W
E
L
N
Y
V
A
L
D
G
N
I
G
C
M
V
N
G
A
G
L
A
M
G
T
M
D
I
V
K
L
H
G
G
E
P
A
N
F
L
D
V
G
G
G
A
T
K
E
R
V
T
E
A
F
K
I
I
L
S
D
D
K
V
K
A
V
L
V
N
I
F
G
G
I
V
R
C
D
L
I
A
D
G
I
I
G
A
V
A
E
V
G
V
N
V
P
V
V
V
R
L
E
G
N
N
A
E
L
G
A
K
K
L
A
D
S
G
L
N
I
I
A
A
K
G
L
T
D
A
A
Q
Q
V
V
A
A
V
-
32
PsiBlast_CBE
91.29
49%
-104
- C3 -
1CQI
4
SUCC_ECOLI
E:
[1-385]
M
N
L
H
E
Y
Q
A
K
Q
L
F
A
R
Y
G
L
P
A
P
V
G
Y
A
C
T
T
P
R
E
A
E
E
A
A
S
K
I
G
-
A
G
P
-
W
V
V
K
C
Q
V
H
A
G
G
R
G
K
-------
A
-------
G
G
V
K
V
V
N
S
K
E
D
I
R
A
F
A
E
N
W
L
G
K
R
L
V
T
Y
Q
T
D
A
N
G
Q
P
V
N
Q
I
L
V
E
A
A
T
D
I
A
K
E
L
Y
L
G
A
V
V
D
R
S
S
R
R
V
V
F
M
A
S
T
E
G
G
V
E
I
E
K
V
A
E
E
T
P
H
L
I
H
K
V
A
L
D
P
L
T
G
P
M
P
Y
Q
G
R
E
L
A
-
F
K
L
G
L
E
G
K
L
V
Q
Q
F
T
K
I
F
M
G
L
A
T
I
F
L
E
R
D
L
A
L
I
E
I
N
P
L
V
I
T
K
Q
G
D
L
I
C
L
D
G
K
L
G
A
D
G
N
A
L
F
R
Q
P
D
L
R
E
M
R
D
Q
S
Q
E
D
P
R
E
A
Q
A
A
Q
W
E
L
N
Y
V
A
L
D
G
N
I
G
C
M
V
N
G
A
G
L
A
M
G
T
M
D
I
V
K
L
H
G
G
E
P
A
N
F
L
D
V
G
G
G
A
T
K
E
R
V
T
E
A
F
K
I
I
L
S
D
D
K
V
K
A
V
L
V
N
I
F
G
G
I
V
R
C
D
L
I
A
D
G
I
I
G
A
V
A
E
V
G
V
N
V
P
V
V
V
R
L
E
G
N
N
A
E
L
G
A
K
K
L
A
D
S
G
L
N
I
I
A
A
K
G
L
T
D
A
A
Q
Q
V
V
A
A
V
-
24
PsiBlast_CBE
91.25
49%
-100
- C3 -
2NU9
4
SUCC_ECOLI
G:
[1-385]
M
N
L
H
E
Y
Q
A
K
Q
L
F
A
R
Y
G
L
P
A
P
V
G
Y
A
C
T
T
P
R
E
A
E
E
A
A
S
K
I
G
-
A
G
P
-
W
V
V
K
C
Q
V
H
A
G
G
R
G
K
-------
A
-------
G
G
V
K
V
V
N
S
K
E
D
I
R
A
F
A
E
N
W
L
G
K
R
L
V
T
Y
Q
T
D
A
N
G
Q
P
V
N
Q
I
L
V
E
A
A
T
D
I
A
K
E
L
Y
L
G
A
V
V
D
R
S
S
R
R
V
V
F
M
A
S
T
E
G
G
V
E
I
E
K
V
A
E
E
T
P
H
L
I
H
K
V
A
L
D
P
L
T
G
P
M
P
Y
Q
G
R
E
L
A
-
F
K
L
G
L
E
G
K
L
V
Q
Q
F
T
K
I
F
M
G
L
A
T
I
F
L
E
R
D
L
A
L
I
E
I
N
P
L
V
I
T
K
Q
G
D
L
I
C
L
D
G
K
L
G
A
D
G
N
A
L
F
R
Q
P
D
L
R
E
M
R
D
Q
S
Q
E
D
P
R
E
A
Q
A
A
Q
W
E
L
N
Y
V
A
L
D
G
N
I
G
C
M
V
N
G
A
G
L
A
M
G
T
M
D
I
V
K
L
H
G
G
E
P
A
N
F
L
D
V
G
G
G
A
T
K
E
R
V
T
E
A
F
K
I
I
L
S
D
D
K
V
K
A
V
L
V
N
I
F
G
G
I
V
R
C
D
L
I
A
D
G
I
I
G
A
V
A
E
V
G
V
N
V
P
V
V
V
R
L
E
G
N
N
A
E
L
G
A
K
K
L
A
D
S
G
L
N
I
I
A
A
K
G
L
T
D
A
A
Q
Q
V
V
A
A
V
-
9
PsiBlast_PDB
91.09
49%
-105
- C3 -
1CQI
4
SUCC_ECOLI
B:
[1-385]
M
N
L
H
E
Y
Q
A
K
Q
L
F
A
R
Y
G
L
P
A
P
V
G
Y
A
C
T
T
P
R
E
A
E
E
A
A
S
K
I
G
-
A
G
P
-
W
V
V
K
C
Q
V
H
A
G
G
R
G
K
-------
A
-------
G
G
V
K
V
V
N
S
K
E
D
I
R
A
F
A
E
N
W
L
G
K
R
L
V
T
Y
Q
T
D
A
N
G
Q
P
V
N
Q
I
L
V
E
A
A
T
D
I
A
K
E
L
Y
L
G
A
V
V
D
R
S
S
R
R
V
V
F
M
A
S
T
E
G
G
V
E
I
E
K
V
A
E
E
T
P
H
L
I
H
K
V
A
L
D
P
L
T
G
P
M
P
Y
Q
G
R
E
L
A
-
F
K
L
G
L
E
G
K
L
V
Q
Q
F
T
K
I
F
M
G
L
A
T
I
F
L
E
R
D
L
A
L
I
E
I
N
P
L
V
I
T
K
Q
G
D
L
I
C
L
D
G
K
L
G
A
D
G
N
A
L
F
R
Q
P
D
L
R
E
M
R
D
Q
S
Q
E
D
P
R
E
A
Q
A
A
Q
W
E
L
N
Y
V
A
L
D
G
N
I
G
C
M
V
N
G
A
G
L
A
M
G
T
M
D
I
V
K
L
H
G
G
E
P
A
N
F
L
D
V
G
G
G
A
T
K
E
R
V
T
E
A
F
K
I
I
L
S
D
D
K
V
K
A
V
L
V
N
I
F
G
G
I
V
R
C
D
L
I
A
D
G
I
I
G
A
V
A
E
V
G
V
N
V
P
V
V
V
R
L
E
G
N
N
A
E
L
G
A
K
K
L
A
D
S
G
L
N
I
I
A
A
K
G
L
T
D
A
A
Q
Q
V
V
A
A
V
-
10
PsiBlast_PDB
91.08
49%
-101
- C3 -
1CQJ
4
SUCC_ECOLI
B:
[1-385]
M
N
L
H
E
Y
Q
A
K
Q
L
F
A
R
Y
G
L
P
A
P
V
G
Y
A
C
T
T
P
R
E
A
E
E
A
A
S
K
I
G
-
A
G
P
-
W
V
V
K
C
Q
V
H
A
G
G
R
G
K
-------
A
-------
G
G
V
K
V
V
N
S
K
E
D
I
R
A
F
A
E
N
W
L
G
K
R
L
V
T
Y
Q
T
D
A
N
G
Q
P
V
N
Q
I
L
V
E
A
A
T
D
I
A
K
E
L
Y
L
G
A
V
V
D
R
S
S
R
R
V
V
F
M
A
S
T
E
G
G
V
E
I
E
K
V
A
E
E
T
P
H
L
I
H
K
V
A
L
D
P
L
T
G
P
M
P
Y
Q
G
R
E
L
A
-
F
K
L
G
L
E
G
K
L
V
Q
Q
F
T
K
I
F
M
G
L
A
T
I
F
L
E
R
D
L
A
L
I
E
I
N
P
L
V
I
T
K
Q
G
D
L
I
C
L
D
G
K
L
G
A
D
G
N
A
L
F
R
Q
P
D
L
R
E
M
R
D
Q
S
Q
E
D
P
R
E
A
Q
A
A
Q
W
E
L
N
Y
V
A
L
D
G
N
I
G
C
M
V
N
G
A
G
L
A
M
G
T
M
D
I
V
K
L
H
G
G
E
P
A
N
F
L
D
V
G
G
G
A
T
K
E
R
V
T
E
A
F
K
I
I
L
S
D
D
K
V
K
A
V
L
V
N
I
F
G
G
I
V
R
C
D
L
I
A
D
G
I
I
G
A
V
A
E
V
G
V
N
V
P
V
V
V
R
L
E
G
N
N
A
E
L
G
A
K
K
L
A
D
S
G
L
N
I
I
A
A
K
G
L
T
D
A
A
Q
Q
V
V
A
A
V
-
31
PsiBlast_CBE
90.87
49%
-101
- C3 -
1CQJ
3
SUCC_ECOLI
E:
[1-385]
M
N
L
H
E
Y
Q
A
K
Q
L
F
A
R
Y
G
L
P
A
P
V
G
Y
A
C
T
T
P
R
E
A
E
E
A
A
S
K
I
G
-
A
G
P
-
W
V
V
K
C
Q
V
H
A
G
G
R
G
K
-------
A
-------
G
G
V
K
V
V
N
S
K
E
D
I
R
A
F
A
E
N
W
L
G
K
R
L
V
T
Y
Q
T
D
A
N
G
Q
P
V
N
Q
I
L
V
E
A
A
T
D
I
A
K
E
L
Y
L
G
A
V
V
D
R
S
S
R
R
V
V
F
M
A
S
T
E
G
G
V
E
I
E
K
V
A
E
E
T
P
H
L
I
H
K
V
A
L
D
P
L
T
G
P
M
P
Y
Q
G
R
E
L
A
-
F
K
L
G
L
E
G
K
L
V
Q
Q
F
T
K
I
F
M
G
L
A
T
I
F
L
E
R
D
L
A
L
I
E
I
N
P
L
V
I
T
K
Q
G
D
L
I
C
L
D
G
K
L
G
A
D
G
N
A
L
F
R
Q
P
D
L
R
E
M
R
D
Q
S
Q
E
D
P
R
E
A
Q
A
A
Q
W
E
L
N
Y
V
A
L
D
G
N
I
G
C
M
V
N
G
A
G
L
A
M
G
T
M
D
I
V
K
L
H
G
G
E
P
A
N
F
L
D
V
G
G
G
A
T
K
E
R
V
T
E
A
F
K
I
I
L
S
D
D
K
V
K
A
V
L
V
N
I
F
G
G
I
V
R
C
D
L
I
A
D
G
I
I
G
A
V
A
E
V
G
V
N
V
P
V
V
V
R
L
E
G
N
N
A
E
L
G
A
K
K
L
A
D
S
G
L
N
I
I
A
A
K
G
L
T
D
A
A
Q
Q
V
V
A
A
V
-
11
PsiBlast_PDB
90.73
48%
-102
- C3 -
1JLL
5
SUCC_ECOLI
B:
[1-386]
M
N
L
H
E
Y
Q
A
K
Q
L
F
A
R
Y
G
L
P
A
P
V
G
Y
A
C
T
T
P
R
E
A
E
E
A
A
S
K
I
G
-
A
G
P
-
W
V
V
K
C
Q
V
H
A
G
G
R
G
K
-------
A
-------
G
G
V
K
V
V
N
S
K
E
D
I
R
A
F
A
E
N
W
L
G
K
R
L
V
T
Y
Q
T
D
A
N
G
Q
P
V
N
Q
I
L
V
E
A
A
T
D
I
A
K
E
L
Y
L
G
A
V
V
D
R
S
S
R
R
V
V
F
M
A
S
T
E
G
G
V
E
I
E
K
V
A
E
E
T
P
H
L
I
H
K
V
A
L
D
P
L
T
G
P
M
P
Y
Q
G
R
E
L
A
-
F
K
L
G
L
E
G
K
L
V
Q
Q
F
T
K
I
F
M
G
L
A
T
I
F
L
E
R
D
L
A
L
I
A
I
N
P
L
V
I
T
K
Q
G
D
L
I
C
L
D
G
K
L
G
A
D
G
N
A
L
F
R
Q
P
D
L
R
E
M
R
D
Q
S
Q
E
D
P
R
E
A
Q
A
A
Q
W
E
L
N
Y
V
A
L
D
G
N
I
G
C
M
V
N
G
A
G
L
A
M
G
T
M
D
I
V
K
L
H
G
G
E
P
A
N
F
L
D
V
G
G
G
A
T
K
E
R
V
T
E
A
F
K
I
I
L
S
D
D
K
V
K
A
V
L
V
N
I
F
G
G
I
V
R
C
D
L
I
A
D
G
I
I
G
A
V
A
E
V
G
V
N
V
P
V
V
V
R
L
E
G
N
N
A
E
L
G
A
K
K
L
A
D
S
G
L
N
I
I
A
A
K
G
L
T
D
A
A
Q
Q
V
V
A
A
V
E
41
HHSearch
85.73
44%
-98
* C3 *
2FP4
3
SUCB2_PIG
B:
[1-393]
M
N
L
Q
E
Y
Q
S
K
K
L
M
S
D
N
G
V
K
V
Q
R
F
F
V
A
D
T
A
N
E
A
L
E
A
A
K
R
L
N
-
A
-
K
E
I
V
L
K
A
Q
I
L
A
G
G
R
G
K
GVFSSGL
K
-------
G
G
V
H
L
T
K
D
P
E
V
V
G
Q
L
A
K
Q
M
I
G
Y
N
L
A
T
K
Q
T
P
K
E
G
V
K
V
N
K
V
M
V
A
E
A
L
D
I
S
R
E
T
Y
L
A
I
L
M
D
R
S
C
N
G
P
V
L
V
G
S
P
Q
G
G
V
D
I
E
E
V
A
A
S
N
P
E
L
I
F
K
E
Q
I
D
I
I
E
G
I
K
D
S
Q
A
Q
R
M
A
-
E
N
L
G
F
L
G
P
L
Q
N
Q
A
A
D
Q
I
K
K
L
Y
N
L
F
L
K
I
D
A
T
Q
V
E
V
N
P
F
G
E
T
P
E
G
Q
V
V
C
F
D
A
K
I
N
F
D
D
N
A
E
F
R
Q
K
D
I
F
A
M
D
D
K
S
E
N
E
P
I
E
N
E
A
A
K
Y
D
L
K
Y
I
G
L
D
G
N
I
A
C
F
V
N
G
A
G
L
A
M
A
T
C
D
I
I
F
L
N
G
G
K
P
A
N
F
L
D
L
G
G
G
V
K
E
S
Q
V
Y
Q
A
F
K
L
L
T
A
D
P
K
V
E
A
I
L
V
N
I
F
G
G
I
V
N
C
A
I
I
A
N
G
I
T
K
A
C
R
E
L
E
L
K
V
P
L
V
V
R
L
E
G
T
N
V
H
E
A
Q
N
I
L
T
N
S
G
L
P
I
T
S
A
V
D
L
E
D
A
A
K
K
A
V
A
S
V
T
12
PsiBlast_PDB
84.34
44%
-94
- C3 -
2FP4
3
SUCB2_PIG
B:
[1-392]
M
N
L
Q
E
Y
Q
S
K
K
L
M
S
D
N
G
V
K
V
Q
R
F
F
V
A
D
T
A
N
E
A
L
E
A
A
K
R
L
N
-
A
K
E
-
I
V
L
K
A
Q
I
L
A
G
G
R
G
K
-------
G
VFSSGLK
G
G
V
H
L
T
K
D
P
E
V
V
G
Q
L
A
K
Q
M
I
G
Y
N
L
A
T
K
Q
T
P
K
E
G
V
K
V
N
K
V
M
V
A
E
A
L
D
I
S
R
E
T
Y
L
A
I
L
M
D
R
S
C
N
G
P
V
L
V
G
S
P
Q
G
G
V
D
I
E
E
V
A
A
S
N
P
E
L
I
F
K
E
Q
I
D
I
I
E
G
I
K
D
S
Q
A
Q
R
M
A
E
N
L
G
F
L
G
P
L
Q
N
Q
A
A
D
Q
I
-
K
K
L
Y
N
L
F
L
K
I
D
A
T
Q
V
E
V
N
P
F
G
E
T
P
E
G
Q
V
V
C
F
D
A
K
I
N
F
D
D
N
A
E
F
R
Q
K
D
I
F
A
M
D
D
K
S
E
N
E
P
I
E
N
E
A
A
K
Y
D
L
K
Y
I
G
L
D
G
N
I
A
C
F
V
N
G
A
G
L
A
M
A
T
C
D
I
I
F
L
N
G
G
K
P
A
N
F
L
D
L
G
G
G
V
K
E
S
Q
V
Y
Q
A
F
K
L
L
T
A
D
P
K
V
E
A
I
L
V
N
I
F
G
G
I
V
N
C
A
I
I
A
N
G
I
T
K
A
C
R
E
L
E
L
K
V
P
L
V
V
R
L
E
G
T
N
V
H
E
A
Q
N
I
L
T
N
S
G
L
P
I
T
S
A
V
D
L
E
D
A
A
K
K
A
V
A
S
V
T
13
PsiBlast_PDB
83.31
44%
-94
- C3 -
2FPG
3
SUCB2_PIG
B:
[1-392]
M
N
L
Q
E
Y
Q
S
K
K
L
M
S
D
N
G
V
K
V
Q
R
F
F
V
A
D
T
A
N
E
A
L
E
A
A
K
R
L
N
-
A
K
E
-
I
V
L
K
A
Q
I
L
A
G
G
R
G
K
-------
G
VFSSGLK
G
G
V
H
L
T
K
D
P
E
V
V
G
Q
L
A
K
Q
M
I
G
Y
N
L
A
T
K
Q
T
P
K
E
G
V
K
V
N
K
V
M
V
A
E
A
L
D
I
S
R
E
T
Y
L
A
I
L
M
D
R
S
C
N
G
P
V
L
V
G
S
P
Q
G
G
V
D
I
E
E
V
A
A
S
N
P
E
L
I
F
K
E
Q
I
D
I
I
E
G
I
K
D
S
Q
A
Q
R
M
A
E
N
L
G
F
L
G
P
L
Q
N
Q
A
A
D
Q
I
-
K
K
L
Y
N
L
F
L
K
I
D
A
T
Q
V
E
V
N
P
F
G
E
T
P
E
G
Q
V
V
C
F
D
A
K
I
N
F
D
D
N
A
E
F
R
Q
K
D
I
F
A
M
D
D
K
S
E
N
E
P
I
E
N
E
A
A
K
Y
D
L
K
Y
I
G
L
D
G
N
I
A
C
F
V
N
G
A
G
L
A
M
A
T
C
D
I
I
F
L
N
G
G
K
P
A
N
F
L
D
L
G
G
G
V
K
E
S
Q
V
Y
Q
A
F
K
L
L
T
A
D
P
K
V
E
A
I
L
V
N
I
F
G
G
I
V
N
C
A
I
I
A
N
G
I
T
K
A
C
R
E
L
E
L
K
V
P
L
V
V
R
L
E
G
T
N
V
H
E
A
Q
N
I
L
T
N
S
G
L
P
I
T
S
A
V
D
L
E
D
A
A
K
K
A
V
A
S
V
T