@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Wbm0538: (2015-12-02 )
MIADRKRSVKQKSDKNNLVGNLDIIKTAGEISLQKGLDFEVIMKALESAIEAVAYQKYGSKSKVVVNIDRSTGEVISYRELKVVDDEPNGEEHNGYGSITLTQAKLIKEDAKVGDTINELLSLNTDLASARIAQQRIAQVIKYEELKKQYEEFKDKVGEIRYGIVKQVEYSDLIIDINGTRAYLPLRNLIGGELFREGDKIKAYIQTVKRSDDGRQIILSRASEGFLEALLSQEIPEIADGLVTVKGIARDAGSRSKVAVFSPDKNIDPVGACVGVKGERIKAIIHELNGEKIDVVHYFSDLGQFVIKAITPAEVSKVIIDESENCVELIVAEDQLSLAIGKKGQNVRLASELIGWKIEILSTQQESERRNRELSQCSALFAEALNLEEIMGQLLVTEGFSSVEDISNASIKELASIEGFNEDIASELRNRANRYLKAENDRKIEELKSLGMESDVINLPLSIDDKIALSEHGIKTLENIADLSSYEFCSILSSSASDKENLKNTVNSIIMEARKKLGVI
Atome Classification :
(20 SA)
-.........10........20........30........40........50........60.......--------.---------70........80....-.--...90........100.......110.....-.-.120--.-.-..-....130.......140.......150.......160.......--.-------170--..---...-----...----.180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280......--------------------.290....---...300.......310......-.320--.......330.......340-.........350--.........----360.......370.......380........390.......400.....---..410.......420..----.....430.......440.......450.......460.......470.......480.......490.......---------500.......510.......520---------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-MIA
D
R
K
R
S
V
KQKSDKNNLVGN
L
D
I
I
KTAG
E
I
SLQKGL
D
F
E
V
I
M
K
A
L
E
S
A
I
E
A
V
A
Y
Q
KYGSKS
K
V
V
V
N
I
--------D---------RSTG
E
V
I
S
Y
R
E
L
K
V
VD-D--EPNGEEHNGY
G
S
I
T
L
T
Q
A
K
L
I
K
E
D
AKV
G
D
T
I
-
N
-
E
L
L
---
S
-L-N
T
-
D
L
A
S
A
R
I
A
Q
Q
R
I
A
Q
V
I
K
Y
E
E
L
K
K
Q
Y
E
E
F
K
D
K
V
G
E
I
-
R
Y
G
I
V
KQ
V
--
E
-------Y----S
D
---
L
I
I
-----
D
IN----G
T
R
A
Y
L
P
L
R
N
LI
G
G
E
L
FREG
D
K
I
K
A
Y
I
Q
T
V
K
RSDDG
R
Q
I
I
L
S
R
AS
E
G
F
L
E
A
L
L
S
QE
I
P
E
I
AD
G
L
V
T
V
K
G
I
ARDAGSR
S
K
V
A
V
FSPDKNIDPV
G
A
C
VGVK
G
E
R
I
K
A
I
I
H
E
L--------------------NG
E
K
I
D
V
V
---
H
Y
F
S
D
L
G
Q
F
V
I
K
AI
T
P
A
E
V
S
K
V
-
I
IDE--SEN
C
V
E
L
I
V
AED
Q
L
S
L
A
I---GKKGQNV
R
L
A
----
S
E
LIG
W
K
I
E
----
I
L
ST
Q
Q
E
S
E
R
R
N
R
E
L
S
Q
C
S
A
L
-
F
A
E
AL
N
L
E
E
I
M
G
Q
L
L
V
TEGF
S
S
V
E
D
IS---
N
A
S
I
K
E
L
A
S
IEGF
N
E
D
I
----
A
S
E
L
R
N
R
A
N
R
YLKAEND
R
K
I
E
E
L
K
SLGMESD
V
I
NLPLSIDD
K
I
A
L
S
EH
G
I
K
T
L
E
N
I
A
DL
S
S
Y
E
F
C
S
I
L
S
SSAS
D
K
---------
E
N
L
K
N
T
V
N
S
I
I
M
E
A
R
K
KLGVI-----------------------
1
PsiBlast_PDB
87.92
32%
-85
- C5 -
4MTN
2
?
A:
[5-392]
--------------------
G
N
-
E
V
L
R
I
V
D
S
I
H
R
D
K
S
I
D
K
E
I
V
F
E
G
V
E
Q
A
I
L
S
A
A
R
K
H
F
G
E
E
E
V
I
E
V
H
I
--------
D
---------
R
T
S
G
Q
--------------------------
P
M
V
K
T
N
G
R
E
I
D
R
D
-
E
L
G
D
I
L
-
G
-
R
I
--------------
S
A
Q
T
-
K
Q
V
M
I
Q
K
I
R
E
A
E
R
D
T
L
F
D
E
Y
A
Q
L
R
G
Q
I
-
V
S
G
T
V
T
R
N
--
E
-------
G
----
S
A
---
I
T
V
-----
N
I
G
----
K
A
E
A
I
L
P
R
S
E
M
I
P
G
E
S
H
R
P
N
E
R
I
R
A
V
V
L
E
V
K
K
M
G
P
R
V
R
V
V
L
S
R
A
H
P
D
F
V
R
R
L
L
E
L
E
I
P
E
V
N
E
R
I
I
E
I
R
S
L
A
R
E
A
G
Y
R
T
K
V
A
V
S
C
A
D
S
N
I
D
P
V
G
A
C
V
G
V
R
G
A
R
I
R
N
V
G
E
E
L
--------------------
G
G
E
R
I
E
V
V
---
R
W
N
D
S
L
Q
V
L
V
P
N
A
M
Q
P
S
E
V
E
D
V
-
I
L
C
P
--
M
L
G
R
V
L
V
L
V
R
D
D
Q
L
S
L
A
I
---
G
K
R
G
Q
N
V
R
L
A
----
S
K
L
V
G
W
D
I
D
----
V
M
T
----
R
E
E
L
D
Q
Q
L
D
Q
A
V
V
A
-
Y
S
Q
I
P
G
V
S
E
E
L
A
E
G
L
V
S
Q
G
F
L
S
F
E
D
L
S
V
IE
P
D
E
L
M
E
M
G
S
L
T
Q
E
Q
A
D
V
----
I
V
E
Y
A
E
R
E
S
E
R
I
E
K
E
Q
D
L
R
R
A
T
E
K
A
E
R
Q
S
Q
E
-------------------------------------------------------------------------------------------------
49
Fugue
85.69
36%
-81
- C5 -
1HH2
-
?
P:
[1-344]
--------------------
M
N
I
G
L
L
E
A
L
D
Q
L
E
E
E
K
G
I
S
K
E
E
V
I
P
I
L
E
K
A
L
V
S
A
Y
R
K
N
F
G
N
S
K
N
V
E
V
V
I
--------
D
---------
R
N
T
G
N
I
K
V
Y
Q
L
L
E
V
V
E
-
E
--
V
E
D
P
A
T
Q
-----
I
S
L
E
E
A
K
K
I
D
P
L
A
E
V
G
S
I
V
-
K
-
K
E
L
---
N
-
V
-
K
N
F
G
R
I
A
A
Q
T
A
K
Q
V
L
I
Q
R
I
R
E
L
E
K
E
K
Q
F
E
K
Y
S
E
L
K
G
T
V
-
T
T
A
E
V
I
R
V
--
M
-------
G
----
E
W
---
A
D
I
-----
R
I
G
----
K
L
E
T
R
L
P
K
K
E
W
I
P
G
E
E
I
K
A
G
D
L
V
K
V
Y
I
I
D
V
V
K
T
T
K
G
P
K
I
L
V
S
R
R
V
P
E
F
V
I
G
L
M
K
L
E
I
P
E
V
E
N
G
I
V
E
I
K
A
I
A
R
E
P
G
V
R
T
K
V
A
V
A
S
N
D
P
N
V
D
P
I
G
A
C
I
G
E
G
G
S
R
I
A
A
I
L
K
E
L
--------------------
K
G
E
K
L
D
V
L
---
K
W
S
D
D
P
K
Q
L
I
A
N
A
L
A
P
A
T
V
I
E
V
E
I
L
D
K
--
E
N
K
A
A
R
V
L
V
P
P
T
Q
L
S
L
A
I
---
G
K
G
G
Q
N
A
R
L
A
----
A
K
L
T
G
W
K
I
D
----
I
K
P
I
M
N
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
HHSearch
85.52
37%
-80
- C5 -
1HH2
-
?
P:
[1-342]
--------------------
M
N
I
G
L
L
E
A
L
D
Q
L
E
E
E
K
G
I
S
K
E
E
V
I
P
I
L
E
K
A
L
V
S
A
Y
R
K
N
F
G
N
S
K
N
V
E
V
V
I
--------
D
---------
R
N
T
G
N
I
K
V
Y
Q
L
L
E
V
V
E
-
E
-------
V
E
D
P
A
T
Q
I
S
L
E
E
A
K
K
I
D
P
L
A
E
V
G
S
I
V
-
K
-
K
E
L
---
N
V
K
-
N
F
-
G
R
I
A
A
Q
T
A
K
Q
V
L
I
Q
R
I
R
E
L
E
K
E
K
Q
F
E
K
Y
S
E
L
K
G
T
V
-
T
T
A
E
V
I
R
V
--
M
-------
G
----
E
W
---
A
D
I
-----
R
I
G
----
K
L
E
T
R
L
P
K
K
E
W
I
P
G
E
E
I
K
A
G
D
L
V
K
V
Y
I
I
D
V
V
K
T
T
K
G
P
K
I
L
V
S
R
R
V
P
E
F
V
I
G
L
M
K
L
E
I
P
E
V
E
N
G
I
V
E
I
K
A
I
A
R
E
P
G
V
R
T
K
V
A
V
A
S
N
D
P
N
V
D
P
I
G
A
C
I
G
E
G
G
S
R
I
A
A
I
L
K
E
L
--------------------
K
G
E
K
L
D
V
L
---
K
W
S
D
D
P
K
Q
L
I
A
N
A
L
A
P
A
T
V
I
E
V
-
E
I
L
D
K-
E
N
K
A
A
R
V
L
V
P
P
T
Q
L
S
L
A
I
---
G
K
G
G
Q
N
A
R
L
A
----
A
K
L
T
G
W
K
I
D
----
I
K
P
I
M
N
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
83.58
38%
-76
- C5 -
1HH2
-
?
P:
[2-338]
---------------------
N
I
G
L
L
E
A
L
D
Q
L
E
E
E
K
G
I
S
K
E
E
V
I
P
I
L
E
K
A
L
V
S
A
Y
R
K
N
F
G
N
S
K
N
V
E
V
V
I
--------
D
---------
R
N
T
G
N
I
K
V
Y
Q
L
L
E
V
V
E
--------
E
V
E
D
P
A
T
Q
I
S
L
E
E
A
K
K
I
D
P
L
A
E
V
G
S
I
V
-
K
-
K
E
L
---
N
-
V
K
N
F
-
G
R
I
A
A
Q
T
A
K
Q
V
L
I
Q
R
I
R
E
L
E
K
E
K
Q
F
E
K
Y
S
E
L
K
G
T
V
-
T
T
A
E
V
I
R
V
MG
E
-------
W
----
A
D
---
I
R
I
-----
G
K
L
----
E
T
R
--
L
P
K
K
E
W
I
P
G
E
E
I
K
A
G
D
L
V
K
V
Y
I
I
D
V
V
K
T
T
K
G
P
K
I
L
V
S
R
R
V
P
E
F
V
I
G
L
M
K
L
E
I
P
E
V
E
N
G
I
V
E
I
K
A
I
A
R
E
P
G
V
R
T
K
V
A
V
A
S
N
D
P
N
V
D
P
I
G
A
C
I
G
E
G
G
S
R
I
A
A
I
L
K
E
L
--------------------
K
G
E
K
L
D
V
L
---
K
W
S
D
D
P
K
Q
L
I
A
N
A
L
A
P
A
T
V
I
E
V
E
I
L
D
K
--
E
N
K
A
A
R
V
L
V
P
P
T
Q
L
S
L
A
I
---
G
K
G
G
Q
N
A
R
L
A
----
A
K
L
T
G
W
K
I
D
----
I
K
P
I
M
N
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
HHSearch
73.28
36%
-89
- C5 -
2ASB
1
NUSA_MYCTU
A:
[4-229]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
T
R
E
G
E
I
-
V
A
G
V
I
Q
R
D
--
S
-------
R
A
N
A
R
G
L
---
V
V
V
-----
R
I
G
T
E
T
K
A
S
E
G
V
I
P
A
A
E
Q
V
P
G
E
S
Y
E
H
G
N
R
L
R
C
Y
V
V
G
V
T
R
G
A
R
E
P
L
I
T
L
S
R
T
H
P
N
L
V
R
K
L
F
S
L
E
V
P
E
I
A
D
G
S
V
E
I
V
A
V
A
R
E
A
G
H
R
S
K
I
A
V
R
S
N
V
A
G
L
N
A
K
G
A
C
I
G
P
M
G
Q
R
V
R
N
V
M
S
E
L
--------------------
S
G
E
K
I
D
I
I
---
D
Y
D
D
D
P
A
R
F
V
A
N
A
L
S
P
A
K
V
V
S
V
-
S
V
I
D
Q-
T
A
R
A
A
R
V
V
V
P
D
F
Q
L
S
L
A
I
---
G
K
E
G
Q
N
A
R
L
A
----
A
R
L
T
G
W
R
I
D
----
I
R
G
D
A
P
P
P
P
P
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
70.72
37%
-87
- C5 -
2ASB
1
NUSA_MYCTU
A:
[4-219]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
T
R
E
G
E
I
-
V
A
G
V
I
Q
R
D
--
S
-------
R
----
A
N
A
R
G
L
V
V
V
R
I
G
T
E
T
K
----
A
S
E
G
V
I
P
A
A
E
Q
V
P
G
E
S
Y
E
H
G
N
R
L
R
C
Y
V
V
G
V
T
R
G
A
R
E
P
L
I
T
L
S
R
T
H
P
N
L
V
R
K
L
F
S
L
E
V
P
E
I
A
D
G
S
V
E
I
V
A
V
A
R
E
A
G
H
R
S
K
I
A
V
R
S
N
V
A
G
L
N
A
K
G
A
C
I
G
P
M
G
Q
R
V
R
N
V
M
S
E
L
--------------------
S
G
E
K
I
D
I
I
---
D
Y
D
D
D
P
A
R
F
V
A
N
A
L
S
P
A
K
V
V
S
V
S
V
I
D
Q
--
T
A
R
A
A
R
V
V
V
P
D
F
Q
L
S
L
A
I
---
G
K
E
G
Q
N
A
R
L
A
----
A
R
L
T
G
W
R
I
D
----
I
R
G
D
A
P
P
P
P
P
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
70.42
37%
-85
- C5 -
2ATW
1
NUSA_MYCTU
C:
[2-219]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
F
S
T
R
E
G
E
I
-
V
A
G
V
I
Q
R
D
--
S
-------
R
----
A
N
ARG
L
V
V
VRIGT
E
T
K
----
A
S
E
G
V
I
P
A
A
E
Q
V
P
G
E
S
Y
E
H
G
N
R
L
R
C
Y
V
V
G
V
T
R
G
A
R
E
P
L
I
T
L
S
R
T
H
P
N
L
V
R
K
L
F
S
L
E
V
P
E
I
A
D
G
S
V
E
I
V
A
V
A
R
E
A
G
H
R
S
K
I
A
V
R
S
N
V
A
G
L
N
A
K
G
A
C
I
G
P
M
G
Q
R
V
R
N
V
M
S
E
L
--------------------
S
G
E
K
I
D
I
I
---
D
Y
D
D
D
P
A
R
F
V
A
N
A
L
S
P
A
K
V
V
S
V
S
V
I
D
Q
--
T
A
R
A
A
R
V
V
V
P
D
F
Q
L
S
L
A
I
---
G
K
E
G
Q
N
A
R
L
A
----
A
R
L
T
G
W
R
I
D
----
I
R
G
D
A
P
P
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
70.02
37%
-82
- C5 -
2ATW
1
NUSA_MYCTU
A:
[3-219]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
S
T
R
E
G
E
I
-
V
A
G
V
I
Q
R
D
--
S
-------
R
----
A
N
A
R
G
L
V
V
V
R
I
G
T
E
T
K
----
A
S
E
G
V
I
P
A
A
E
Q
V
P
G
E
S
Y
E
H
G
N
R
L
R
C
Y
V
V
G
V
T
R
G
A
R
E
P
L
I
T
L
S
R
T
H
P
N
L
V
R
K
L
F
S
L
E
V
P
E
I
A
D
G
S
V
E
I
V
A
V
A
R
E
A
G
H
R
S
K
I
A
V
R
S
N
V
A
G
L
N
A
K
G
A
C
I
G
P
M
G
Q
R
V
R
N
V
M
S
E
L
--------------------
S
G
E
K
I
D
I
I
---
D
Y
D
D
D
P
A
R
F
V
A
N
A
L
S
P
A
K
V
V
S
V
S
V
I
D
Q
--
T
A
R
A
A
R
V
V
V
P
D
F
Q
L
S
L
A
I
---
G
K
E
G
Q
N
A
R
L
A
----
A
R
L
T
G
W
R
I
D
----
I
R
G
D
A
P
P
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
66.33
38%
-8
- C5 -
1L2F
-
?
A:
[2-338]
---------------------
N
I
G
L
L
E
A
L
D
Q
L
E
E
E
K
G
I
S
K
E
E
V
I
P
I
L
E
K
A
L
V
S
A
Y
R
K
N
F
G
N
S
K
N
V
E
V
V
I
--------
D
---------
R
N
T
G
N
I
K
V
Y
Q
L
L
E
V
V
E
--------
E
V
E
D
P
A
T
Q
I
S
L
E
E
A
K
K
I
D
P
L
A
E
V
G
S
I
V
-
K
-
K
E
L
---
N
-
V
K
N
F
-
G
R
I
A
A
Q
T
A
K
Q
V
L
I
Q
R
I
R
E
L
E
K
E
K
Q
F
E
K
Y
S
E
L
K
G
T
V
-
T
T
A
E
V
I
R
V
MG
E
-------
W
----
A
D
---
I
R
I
-----
G
K
L
----
E
T
R
--
L
P
K
K
E
W
I
P
G
E
E
I
K
A
G
D
L
V
K
V
Y
I
I
D
V
V
K
T
T
K
G
P
K
I
L
V
S
R
R
V
P
E
F
V
I
G
L
M
K
L
E
I
P
E
V
E
N
G
I
V
E
I
K
A
I
A
R
E
P
G
V
R
T
K
V
A
V
A
S
N
D
P
N
V
D
P
I
G
A
C
I
G
E
G
G
S
R
I
A
A
I
L
K
E
L
--------------------
K
G
E
K
L
D
V
L
---
K
W
S
D
D
P
K
Q
L
I
A
N
A
L
A
P
A
T
V
I
E
V
E
I
L
D
K
--
E
N
K
A
A
R
V
L
V
P
P
T
Q
L
S
L
A
I
---
G
K
G
G
Q
N
A
R
L
A
----
A
K
L
T
G
W
K
I
D
----
I
K
P
I
M
N
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
53
Fugue
50.52
18%
-9
- C2 -
4OPU
3
?
A:
[2-453]
----------------------------------
M
K
E
L
K
Y
D
V
L
I
I
G
G
G
F
A
G
S
S
A
A
Y
Q
L
S
R
R
G
L
K
I
L
L
V
D
SKPWNRIG
D
---------
K
P
C
G
D
A
V
S
K
A
H
F
D
K
L
G
M
P
--
Y
P
K
G
E
E
----
L
E
N
K
I
N
G
I
K
L
Y
S
P
D
M
Q
T
V
W
T
V
-
N
H
E
G
F
---
E
-
L
-
N
A
-
P
L
Y
N
Q
R
V
L
K
E
A
Q
D
R
G
V
E
I
W
D
L
T
T
A
M
K
P
I
F
E
D
-
G
Y
V
-
K
G
A
V
L
F
N
R
--
R
TN
E
E
L
T
V
Y
----
S
K
---
V
V
V
-----
E
A
T
----
G
Y
S
R
--
S
F
R
S
K
L
P
P
E
L
------------
P
I
T
E
D
L
D
D
K
D
-----
A
D
V
A
Y
R
E
V
L
L
T
K
E
D
I
E
D
H
D
---
Y
L
R
I
F
I
D
Q
E
T
S
P
G
G
Y
W
W
Y
F
P
-
K
G
K
N
K
V
N
V
G
L
G
I
Q
G
G
M
G
Y
P
S
I
H
E
Y
--------------------
Y
K
K
Y
L
D
K
Y
---
A
P
D
V
D
K
S
K
L
L
V
K
G
G
A
L
V
P
T
R
R
P
-
L
Y
T
M
--
A
W
N
G
I
-
I
V
I
G
D
S
G
F
T
V
N
P
VHG
G
G
K
G
S
A
M
I
S
G
----
Y
C
A
A
K
A
I
L
S
----
A
F
E
T
G
D
F
S
A
S
G
L
W
D
M
N
I
C
Y
V
N
E
Y
G
A
K
Q
A
S
L
D
I
F
R
R
F
L
--------
Q
K
L
S
---
N
D
D
I
N
Y
G
M
K
K
K
I
I
K
E
E
D
----
L
L
E
A
S
E
K
G
D
L
H
L
S
V
A
D
K
A
M
-
R
V
I
S
G
L
G
R
P
S
-----------
L
L
F
K
L
K
A
V
A
E
S
M
K
K
I
K
E
L
Y
L
N
-----
Y
P
R
S
P
S
S
L
---------
G
S
W
R
R
E
V
D
N
V
L
T
E
F
N
K
S
L
S
-------------------------
57
Fugue
44.55
13%
3
- C1 -
1KFQ
1
PGM1_PARTE
A:
[2-572]
Q
Q
V
I
P
A
P
R
V
Q
V
T
Q
P
Y
A
G
Q
K
P
G
T
S
G
L
R
K
K
V
S
E
A
T
-
Q
P
N
----
Y
L
E
N
F
V
Q
S
I
F
N
T
L
R
K
D
E
L
K
P
K
N
V
L
F
V
G
G
--------
D
GRYF
N
R
Q
A
I
F
S
I
I
R
L
A
Y
A
N
D
I
S
E
V
H
-
V
--
G
Q
A
G
-----
L
M
S
T
P
A
S
S
H
Y
I
R
K
V
N
E
E
V
G
N
C
I
-
G
-
G
I
I
L
T
A
S
-
H
-
N
P
-
G
G
K
E
H
G
D
F
G
I
K
F
N
V
R
T
G
A
P
A
P
E
D
F
T
D
Q
I
Y
T
H
T
T
K
I
K
E
Y
L
T
V
D
Y
E
--
F
-------
E
----
K
H
---
I
N
L
-----
D
Q
I
----
G
V
Y
K
F
E
G
T
R
L
E
K
S
H
F
E
V
K
V
V
D
T
V
Q
D
Y
T
Q
L
M
Q
K
L
F
D
F
D
L
L
K
G
L
F
S
N
K
D
-
F
S
F
R
F
D
---
G
M
H
G
V
A
G
P
Y
A
K
H
I
F
G
T
L
L
G
C
S
K
E
S
L
L
N
C
D
P
S
E
D
F
G
G
G
H
P
D
P
N
L
T
Y
A
H
D
L
V
E
L
L
DIHKKKDVGTVPQ
F
G
A
A
C
D
G
D
A
D
R
N
M
I
L
G
RQ
F
F
V
T
P
S
D
S
L
A
V
I
A
A
N
A
N
L
I
F
K
----
N
G
--
L
L
G
A
A
R
S
M
P
T
S
G
A
L
D
K
V
A
---
A
K
N
G
I
K
L
F
E
T
P
TG-
W
K
F
F
G
N
L
M
D
A
GLI
N
L
C
G
E
E
S
F
G
T
G
S
N
H
I
R
E
K
D
G
I
-
W
A
V
L
A
W
L
T
I
L
A
H
K
N
K
N
T
D
H
F
V
T
V
E
E
I
V
---
T
Q
Y
W
Q
Q
F
G
R
N
Y
Y
S
R
Y
D
Y
E
QVD
S
A
G
A
N
K
M
M
E
H
L
K
T
K
F
Q
--
Y
F
E
Q
L
K
--------
Q
G
N
K
A
D
I
Y
D
Y
V
D
P
V
D
Q
S
V
S
K
N
Q
G
V
R
F
V
F
G
D
G
S
R
I
I
F
R
L
S
G
T
G
S
V
G
A
T
I
R
I
Y
F
E
Q
F
E
Q
--
Q
Q
I
Q
H
E
T
A
T
A
L
A
N
I
I
K
L
G
L
E
I
S
D
I
A
Q
F
T
GRNEPTVIT
50
Fugue
43.20
32%
-36
- C4 -
1WCL
-
NUSA_ECOLI
A:
[351-426]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
A
H
A
A
I
D
T
-
F
T
K
Y
L
D
I
D
E
D
F
A
T
V
L
V
E
E
G
F
S
T
L
E
E
L
A
---
Y
V
P
M
K
E
L
L
E
I
E
G
L
D
E
P
T
----
V
E
A
L
R
E
R
A
K
N
A
L
A
T
I
A
Q
A
Q
E
E
S
L
G
--------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
42.51
39%
-40
- C4 -
1U9L
2
NUSA_ECOLI
A:
[8-63]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
T
K
Y
L
D
I
D
E
D
F
A
T
V
L
V
E
E
G
F
S
T
L
E
E
L
A
---
Y
V
P
M
K
E
L
L
E
I
E
G
L
D
E
P
T
----
V
E
A
L
R
E
R
A
K
N
A
L
A
T
I
A
Q
---------------------------------------------------------------------------------------------------------------
22
PsiBlast_CBE
42.06
39%
-42
- C4 -
1U9L
1
B:
[8-63]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
T
K
Y
L
D
I
D
E
D
F
A
T
V
L
V
E
E
G
F
S
T
L
E
E
L
A
---
Y
V
P
M
K
E
L
L
E
I
E
G
L
D
E
P
T
----
V
E
A
L
R
E
R
A
K
N
A
L
A
T
I
A
Q
A
Q
-------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
41.40
39%
-40
- C4 -
1WCL
-
NUSA_ECOLI
A:
[359-414]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
T
K
Y
L
D
I
D
E
D
F
A
T
V
L
V
E
E
G
F
S
T
L
E
E
L
A
---
Y
V
P
M
K
E
L
L
E
I
E
G
L
D
E
P
T
----
V
E
A
L
R
E
R
A
K
N
A
L
--------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
40.32
31%
-73
- C5 -
2CXC
-
?
A:
[17-80]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
F
H
S
I
T
G
V
T
A
Y
R
C
-
I
V
D
E
--
E
N
N
R
L
I
F
L
V
S
E
G
E
A
G
R
A
I
---
G
R
G
G
R
L
I
K
L
L
----
R
E
A
L
G
K
N
I
E
----
V
V
E
Y
S
S
D
L
E
R
I
V
K
N
L
F
P
G
V
K
I
-
E
S
I
N
V
R
E
R
N
G
V
K
Q
V
V
I
K
V
S
E
D
D
K
G
A
A
I
---
G
K
G
G
K
N
V
K
R
A
R
L
V
L
S
K
L
----
F
G
V
E
K
V
V
I
R
-----------------------------------------------------------------------------------------------------------------------
29
HHSearch
40.18
29%
-26
- C4 -
2KWP
-
NUSA_ECOLI
A:
[1-128]
--------------------
M
N
K
E
I
L
A
V
V
E
A
V
S
N
E
K
A
L
P
R
E
K
I
F
E
A
L
E
S
A
L
A
T
A
T
K
K
K
Y
E
Q
E
I
D
V
R
V
Q
I
--------
D
---------
R
K
S
G
D
F
D
T
F
R
R
W
L
V
V
D
-
E
-------
V
T
Q
P
T
K
E
I
T
L
E
A
A
R
Y
E
D
E
S
L
N
L
G
D
Y
V
-
E
-
D
Q
I
---
E
S
V
-
T
F
-
D
R
I
T
T
Q
T
A
K
Q
V
I
V
Q
K
V
R
E
A
E
R
A
M
L
V
P
R
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
39.57
31%
-28
- C4 -
2KWP
-
NUSA_ECOLI
A:
[2-119]
---------------------
N
K
E
I
L
A
V
V
E
A
V
S
N
E
K
A
L
P
R
E
K
I
F
E
A
L
E
S
A
L
A
T
A
T
K
K
K
Y
E
Q
E
I
D
V
R
V
Q
I
--------
D
---------
R
K
S
G
D
F
D
T
F
R
R
W
L
V
V
D
-
E
VT
Q
P
T
K
E
-------
I
T
L
E
A
A
R
Y
E
D
E
S
L
N
L
G
D
Y
V
E
D
-
Q
I
E
---
S
-
V
-
T
F
-
D
R
I
T
T
Q
T
A
K
Q
V
I
V
Q
K
V
R
E
A
E
R
A
M
L
V
P
R
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
52
Fugue
39.52
17%
-34
- C4 -
2A1J
1
B:
[13-91]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
P
A
D
L
L
M
E
K
L
E
Q
D
F
V
S
R
V
T
E
C
-
L
T
T
V
K
S
V
N
K
T
D
S
Q
T
L
L
T
T
-
F
G
S
L
E
Q
L
I
---
A
A
S
R
E
D
L
A
L
C
P
G
L
G
P
Q
K
----
A
R
R
L
F
D
V
L
H
E
P
F
L
K
V
-----------------------------------------------------------------------------------------------------------------
31
HHSearch
38.26
31%
-75
- C5 -
2CXC
-
?
A:
[20-139]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
I
T
G
V
T
A
Y
R
C
I
V
D
E
E
N
N
R
L
I
F
L
V
S
E
G
-----
E
A
G
R
A
I
G
R
G
G
R
L
I
K
L
L
R
-
E
A
--------------------
L
G
K
N
I
E
V
V
---
E
Y
S
S
D
L
E
R
I
V
K
N
L
F
P
G
V
K
I
E
S
I
-
N
V
R
E
R
N
G
V
K
Q
V
V
I
K
V
S
E
D
D
K
G
A
A
I
---
G
K
G
G
K
N
V
K
R
A
R
L
V
L
S
K
L
F
G
V
E
K
V
----
V
I
R
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------