@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Wbm0566: (2015-12-02 )
MKNYRFGTKVLIIGSGAAGYAAAIYAARANLEPVVVTGMQPGGQLTITMGVENYPGFVSIQGPELMKQMRLHVEKVGAEIVNDEIKSVEQLEYSNEYKFRSSGNNDDYYSNAVIIAAGSQAKWLGLESERKFQGYGVSACATCDGAFFRNKIVAVIGGGNTAVEEAIFLTRFAKEVILIHRRDKLRAEKIMQDRLFANNKIKVIWNHTVEQVLGEENPKKVTGITIKSTKIDEIQELRVNGVFIAIGHAPNTGVFKSFIEMDEQGYIITKPGTTLTSRAGVFAAGDVQDKVYRQAVVAAGTGCMAALDAEKFLECTSK
Atome Classification :
(40 SA)
.........10........20........30.-...-----.--..-----.-----40----.-----........50.......-.-60.........70........80........90....--....100--....--...110........120....----...130---........140...--.--...150.......160.......170.......180.......---190....---...200.......210....-...--220.......230........240.......250.....-----.----.260.......270----.......280.......290-........300.......310......
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MKNYRFG
T
K
V
L
I
I
GSGA
A
G
Y
A
A
A
I
Y
A
ARANLE-
P
V
V
-----
V
--
T
G
-----M-----Q-----P-----G
G
Q
L
T
I
T
M
GVENYP
G
F
V
-
S
-I-Q
G
P
E
L
M
K
Q
M
R
L
H
V
E
K
V
G
A
E
I
V
N
D
E
I
K
S
V
E
Q
L
EYSN--
E
Y
K
FRSS--GNND--DYYS-
N
A
V
I
I
AAGSQ
A
K
W
LGL----ESERK----FQGYG
V
S
A
C
ATCD
G
--
A
--
F
FR
N
K
I
V
A
V
IGGG
N
T
A
V
E
E
A
I
F
L
T
R
F
A
K
E
V
I
L
I
H
R
R
D
K
L
R
A
E
K
---
I
M
Q
D
R
LF---ANN
K
I
K
V
I
W
N
H
T
V
E
Q
V
LGEE-NPK--
K
V
T
G
I
T
I
KST
K
-
I
D
E
I
Q
E
LRVN
G
V
F
I
A
IGHAP
N
T
G
V
F
K
S
-----
F
----
I
EMDEQ
G
Y
I
I
TKPG----TTLTSRAG
V
F
AAG
D
V
Q
D
K
V
--
Y
R
Q
A
V
V
AAGT
G
C
M
A
A
L
D
A
E
K
F
L
E
C
TSK
1
PsiBlast_PDB
98.00
54%
-117
- C2 -
4JNQ
2
?
A:
[28-334]
--------
P
V
I
V
I
G
S
G
P
A
G
Y
T
A
A
I
Y
A
A
R
A
M
L
K
-
P
V
V
-----
I
--
A
G
-----
L
-----
Q
-----
Q
-----
G
G
Q
L
M
I
T
T
D
V
E
N
Y
P
G
Y
A
E
P
-
V
-
Q
G
P
W
M
M
E
Q
M
A
R
Q
A
E
N
V
G
A
Q
I
V
H
D
I
I
T
E
V
E
----
T
T
--
V
R
P
F
R
L
K
--
G
D
S
G
--
T
I
Y
T
C
D
A
L
I
I
A
T
G
A
Q
A
K
W
L
G
L
----
E
S
E
Q
T
----
F
M
G
G
G
V
S
A
C
A
T
C
D
G
--
F
--
F
Y
R
G
K
D
V
V
V
V
G
G
G
N
T
A
V
E
E
A
L
Y
L
S
H
I
A
K
S
V
T
I
V
H
R
R
D
G
F
R
A
E
K
---
I
M
Q
D
R
L
L
---
S
R
E
N
V
S
V
V
W
N
S
V
I
D
E
I
L
G
T
E
A
R
--GA
T
V
T
G
V
R
L
K
N
I
V
-
T
G
E
T
Q
E
R
A
T
H
G
V
F
I
A
I
G
H
A
P
A
V
S
L
F
E
G
-----
K
----
L
K
Q
K
P
N
G
Y
L
W
T
A
P
D
----
S
T
A
T
D
V
P
G
I
F
A
A
G
D
V
T
D
D
I
--
Y
R
Q
A
V
T
A
A
G
M
G
C
M
A
A
L
E
A
E
R
W
L
A
A
Q
E
-
8
PsiBlast_PDB
94.26
47%
-114
- C2 -
1VDC
2
TRXB1_ARATH
A:
[9-323]
-------
T
R
L
C
I
V
G
S
G
P
A
A
H
T
A
A
I
Y
A
A
R
A
E
L
K
-
P
L
L
-----
F
--
E
G
WMAND
I
-----
A
-----
P
-----
G
G
Q
L
T
T
T
T
D
V
E
N
F
P
G
F
P
E
G
-
I
-
L
G
V
E
L
T
D
K
F
R
K
Q
S
E
R
F
G
T
T
I
F
T
E
---
T
V
T
K
V
D
F
S
S
--
K
-
P
F
K
L
F
--
T
D
S
K
--
A
I
L
A
-
D
A
V
I
L
A
I
G
A
V
A
K
R
L
S
F
VGSG
E
V
L
G
G
----
F
W
N
R
G
I
S
A
C
A
V
C
D
G
--
A
AP
I
F
R
N
K
P
L
A
V
I
G
G
G
D
S
A
M
E
E
A
N
F
L
T
K
Y
G
S
K
V
Y
I
I
H
R
R
D
A
F
R
A
S
K
---
I
M
Q
Q
R
A
L
---
S
N
P
K
I
D
V
I
W
N
S
S
V
V
E
A
Y
G
D
G
-
E
R
D
--
V
L
G
G
L
K
V
K
N
V
V
-
T
G
D
V
S
D
L
K
V
S
G
L
F
F
A
I
G
H
E
P
A
T
K
F
L
D
G
-----
G
----
V
E
L
D
S
D
G
Y
V
V
T
K
P
G
----
T
T
Q
T
S
V
P
G
V
F
A
A
G
D
V
Q
D
K
K
--
Y
R
Q
A
I
T
A
A
G
T
G
C
M
A
A
L
D
A
E
H
Y
L
Q
E
I
--
4
PsiBlast_PDB
92.83
52%
-109
- C2 -
1TRB
1
TRXB_ECOLI
A:
[6-314]
-------
S
K
L
L
I
L
G
S
G
P
A
G
Y
T
A
A
V
Y
A
A
R
A
N
L
Q
-
P
V
L
-----
I
--
T
G
-----
M
-----
E
-----
K
-----
G
G
Q
L
T
T
T
T
E
V
E
N
W
P
G
D
P
-
N
D
L
-
T
G
P
L
L
M
E
R
M
H
E
H
A
T
K
F
E
T
E
I
I
F
D
H
I
N
K
V
D
L
----
Q
--
N
R
P
F
R
L
N
--
G
D
N
G
--
E
Y
T
C
-
D
A
L
I
I
A
T
G
A
S
A
R
Y
L
G
L
----
P
S
E
E
A
----
F
K
G
R
G
V
S
A
C
A
T
S
D
G
--
F
--
F
Y
R
N
Q
K
V
A
V
I
G
G
G
N
T
A
V
E
E
A
L
Y
L
S
N
I
A
S
E
V
H
L
I
H
R
R
D
G
F
R
A
E
K
---
I
L
I
K
R
L
M
D
K
V
E
N
G
N
I
I
L
H
T
N
R
T
L
E
E
V
T
G
D
Q
---
M
--
G
V
T
G
V
R
L
R
D
T
Q
N
S
D
N
I
E
S
L
D
V
A
G
L
F
V
A
I
G
H
S
P
N
T
A
I
F
E
G
-----
Q
----
L
E
L
-
E
N
G
Y
I
K
V
Q
S
G
IHGN
A
T
Q
T
S
I
P
G
V
F
A
A
G
D
V
M
D
H
I
--
Y
R
Q
A
I
T
S
A
G
T
G
C
M
A
A
L
D
A
E
R
Y
L
D
G
L
--
2
PsiBlast_PDB
92.62
53%
-109
- C2 -
1CL0
1
TRXB_ECOLI
A:
[6-314]
-------
S
K
L
L
I
L
G
S
G
P
A
G
Y
T
A
A
V
Y
A
A
R
A
N
L
Q
-
P
V
L
-----
I
--
T
G
-----
M
-----
E
-----
K
-----
G
G
Q
L
T
T
T
T
E
V
E
N
W
P
G
D
P
-
N
D
L
-
T
G
P
L
L
M
E
R
M
H
E
H
A
T
K
F
E
T
E
I
I
F
D
H
I
N
K
V
D
L
----
Q
--
N
R
P
F
R
L
N
--
G
D
N
G
--
E
Y
T
C
-
D
A
L
I
I
A
T
G
A
S
A
R
Y
L
G
L
----
P
S
E
E
A
----
F
K
G
R
G
V
S
A
C
A
T
C
D
G
--
F
--
F
Y
R
N
Q
K
V
A
V
I
G
G
G
N
T
A
V
E
E
A
L
Y
L
S
N
I
A
S
E
V
H
L
I
H
R
R
D
G
F
R
A
E
K
---
I
L
I
K
R
L
M
D
K
V
E
N
G
N
I
I
L
H
T
N
R
T
L
E
E
V
T
G
D
Q
---
M
--
G
V
T
G
V
R
L
R
D
T
Q
N
S
D
N
I
E
S
L
D
V
A
G
L
F
V
A
I
G
H
S
P
N
T
A
I
F
E
G
-----
Q
----
L
E
L
-
E
N
G
Y
I
K
V
Q
S
G
IHGN
A
T
Q
T
S
I
P
G
V
F
A
A
G
D
V
M
D
H
I
--
Y
R
Q
A
I
T
S
A
G
T
G
C
M
A
A
L
D
A
E
R
Y
L
D
G
L
A
-
23
PsiBlast_CBE
92.31
52%
-109
- C2 -
1F6M
3
TRXB_ECOLI
B:
[6-314]
-------
S
K
L
L
I
L
G
S
G
P
A
G
Y
T
A
A
V
Y
A
A
R
A
N
L
Q
-
P
V
L
-----
I
--
T
G
-----
M
-----
E
-----
K
-----
G
G
Q
L
T
T
T
T
E
V
E
N
W
P
G
D
P
-
N
D
L
-
T
G
P
L
L
M
E
R
M
H
E
H
A
T
K
F
E
T
E
I
I
F
D
H
I
N
K
V
D
L
----
Q
--
N
R
P
F
R
L
N
--
G
D
N
G
--
E
Y
T
C
-
D
A
L
I
I
A
T
G
A
S
A
R
Y
L
G
L
----
P
S
E
E
A
----
F
K
G
R
G
V
S
A
S
A
T
C
D
G
--
F
--
F
Y
R
N
Q
K
V
A
V
I
G
G
G
N
T
A
V
E
E
A
L
Y
L
S
N
I
A
S
E
V
H
L
I
H
R
R
D
G
F
R
A
E
K
---
I
L
I
K
R
L
M
DKV
E
N
G
N
I
I
L
H
T
N
R
T
L
E
E
V
T
G
D
Q
---
M
--
G
V
T
G
V
R
L
R
D
T
Q
N
S
D
N
I
E
S
L
D
V
A
G
L
F
V
A
I
G
H
S
P
N
T
A
I
F
E
G
-----
Q
----
L
E
L
-
E
N
G
Y
I
K
V
Q
S
G
IHGN
A
T
Q
T
S
I
P
G
V
F
A
A
G
D
V
M
D
H
I
--
Y
R
Q
A
I
T
S
A
G
T
G
C
M
A
A
L
D
A
E
R
Y
L
D
G
L
A
D
21
PsiBlast_CBE
92.16
52%
-110
- C2 -
1F6M
3
TRXB_ECOLI
F:
[6-314]
-------
S
K
L
L
I
L
G
S
G
P
A
G
Y
T
A
A
V
Y
A
A
R
A
N
L
Q
-
P
V
L
-----
I
--
T
G
-----
M
-----
E
-----
K
-----
G
G
Q
L
T
T
T
T
E
V
E
N
W
P
G
D
P
-
N
D
L
-
T
G
P
L
L
M
E
R
M
H
E
H
A
T
K
F
E
T
E
I
I
F
D
H
I
N
K
V
D
L
----
Q
--
N
R
P
F
R
L
N
--
G
D
N
G
--
E
Y
T
C
-
D
A
L
I
I
A
T
G
A
S
A
R
Y
L
G
L
----
P
S
E
E
A
----
F
K
G
R
G
V
S
A
S
A
T
C
D
G
--
F
--
F
Y
R
N
Q
K
V
A
V
I
G
G
G
N
T
A
V
E
E
A
L
Y
L
S
N
I
A
S
E
V
H
L
I
H
R
R
D
G
F
R
A
E
K
---
I
L
I
K
R
L
M
DKV
E
N
G
N
I
I
L
H
T
N
R
T
L
E
E
V
T
G
D
Q
---
M
--
G
V
T
G
V
R
L
R
D
T
Q
N
S
D
N
I
E
S
L
D
V
A
G
L
F
V
A
I
G
H
S
P
N
T
A
I
F
E
G
-----
Q
----
L
E
L
-
E
N
G
Y
I
K
V
Q
S
G
IHGN
A
T
Q
T
S
I
P
G
V
F
A
A
G
D
V
M
D
H
I
--
Y
R
Q
A
I
T
S
A
G
T
G
C
M
A
A
L
D
A
E
R
Y
L
D
G
L
A
D
63
HHSearch
91.69
48%
-109
- C2 -
1VDC
2
TRXB1_ARATH
A:
[4-325]
--
L
E
T
H
N
T
R
L
C
I
V
G
S
G
P
A
A
H
T
A
A
I
Y
A
A
R
A
E
L
K
-
P
L
L
-----
F
--
E
G
-----
W
MANDI
A
-----
P
-----
G
G
Q
L
T
T
T
T
D
V
E
N
F
P
G
F
P
E
G
-
I
-
L
G
V
E
L
T
D
K
F
R
K
Q
S
E
R
F
G
T
T
I
F
T
E
T
V
T
K
V
D
F
--
S
S
K
--
P
F
K
L
F
T
----
D
S
K
--
A
I
L
A
-
D
A
V
I
L
A
I
G
A
V
A
K
R
L
S
F
----
V
G
S
G
E
VLGG
F
W
N
R
G
I
S
A
C
A
V
C
D
G
AA
P
--
I
F
R
N
K
P
L
A
V
I
G
G
G
D
S
A
M
E
E
A
N
F
L
T
K
Y
G
S
K
V
Y
I
I
H
R
R
D
A
F
R
A
S
K
---
I
M
Q
Q
R
A
L
---
S
N
P
K
I
D
V
I
W
N
S
S
V
V
E
A
Y
G
D
G
-
E
R
D
--
V
L
G
G
L
K
V
K
N
V
V
-
T
G
D
V
S
D
L
K
V
S
G
L
F
F
A
I
G
H
E
P
A
T
K
F
L
D
G
-----
G
----
V
E
L
D
S
D
G
Y
V
V
T
K
P
G
----
T
T
Q
T
S
V
P
G
V
F
A
A
G
D
V
Q
D
K
K
--
Y
R
Q
A
I
T
A
A
G
T
G
C
M
A
A
L
D
A
E
H
Y
L
Q
E
I
--
3
PsiBlast_PDB
91.54
52%
-109
- C2 -
1F6M
3
TRXB_ECOLI
A:
[6-314]
-------
S
K
L
L
I
L
G
S
G
P
A
G
Y
T
A
A
V
Y
A
A
R
A
N
L
Q
-
P
V
L
-----
I
--
T
G
-----
M
-----
E
-----
K
-----
G
G
Q
L
T
T
T
T
E
V
E
N
W
P
G
D
P
-
N
D
L
-
T
G
P
L
L
M
E
R
M
H
E
H
A
T
K
F
E
T
E
I
I
F
D
H
I
N
K
V
D
L
----
Q
--
N
R
P
F
R
L
N
--
G
D
N
G
--
E
Y
T
C
-
D
A
L
I
I
A
T
G
A
S
A
R
Y
L
G
L
----
P
S
E
E
A
----
F
K
G
R
G
V
S
A
S
A
T
C
D
G
--
F
--
F
Y
R
N
Q
K
V
A
V
I
G
G
G
N
T
A
V
E
E
A
L
Y
L
S
N
I
A
S
E
V
H
L
I
H
R
R
D
G
F
R
A
E
K
---
I
L
I
K
R
L
M
D
K
V
E
N
G
N
I
I
L
H
T
N
R
T
L
E
E
V
T
G
D
Q
---
M
--
G
V
T
G
V
R
L
R
D
T
Q
N
S
D
N
I
E
S
L
D
V
A
G
L
F
V
A
I
G
H
S
P
N
T
A
I
F
E
G
-----
Q
----
L
E
L
-
E
N
G
Y
I
K
V
Q
S
G
IHGN
A
T
Q
T
S
I
P
G
V
F
A
A
G
D
V
M
D
H
I
--
Y
R
Q
A
I
T
S
A
G
T
G
C
M
A
A
L
D
A
E
R
Y
L
D
G
L
A
D
22
PsiBlast_CBE
91.43
52%
-110
- C2 -
1F6M
3
TRXB_ECOLI
E:
[6-314]
-------
S
K
L
L
I
L
G
S
G
P
A
G
Y
T
A
A
V
Y
A
A
R
A
N
L
Q
-
P
V
L
-----
I
--
T
G
-----
M
-----
E
-----
K
-----
G
G
Q
L
T
T
T
T
E
V
E
N
W
P
G
D
P
-
N
D
L
-
T
G
P
L
L
M
E
R
M
H
E
H
A
T
K
F
E
T
E
I
I
F
D
H
I
N
K
V
D
L
----
Q
--
N
R
P
F
R
L
N
--
G
D
N
G
--
E
Y
T
C
-
D
A
L
I
I
A
T
G
A
S
A
R
Y
L
G
L
----
P
S
E
E
A
----
F
K
G
R
G
V
S
A
S
A
T
C
D
G
--
F
--
F
Y
R
N
Q
K
V
A
V
I
G
G
G
N
T
A
V
E
E
A
L
Y
L
S
N
I
A
S
E
V
H
L
I
H
R
R
D
G
F
R
A
E
K
---
I
L
I
K
R
L
M
DKV
E
N
G
N
I
I
L
H
T
N
R
T
L
E
E
V
T
G
D
Q
---
M
--
G
V
T
G
V
R
L
R
D
T
Q
N
S
D
N
I
E
S
L
D
V
A
G
L
F
V
A
I
G
H
S
P
N
T
A
I
F
E
G
-----
Q
----
L
E
L
-
E
N
G
Y
I
K
V
Q
S
G
IHGN
A
T
Q
T
S
I
P
G
V
F
A
A
G
D
V
M
D
H
I
--
Y
R
Q
A
I
T
S
A
G
T
G
C
M
A
A
L
D
A
E
R
Y
L
D
G
L
A
D
71
HHSearch
90.73
52%
-108
- C2 -
1TRB
1
TRXB_ECOLI
A:
[2-316]
---
T
T
K
H
S
K
L
L
I
L
G
S
G
P
A
G
Y
T
A
A
V
Y
A
A
R
A
N
L
Q
-
P
V
L
-----
I
--
T
G
-----
M
-----
E
-----
K
-----
G
G
Q
L
T
T
T
T
E
V
E
N
W
P
G
D
P
N
D
-
L
-
T
G
P
L
L
M
E
R
M
H
E
H
A
T
K
F
E
T
E
I
I
F
D
H
I
N
K
V
D
L
--
Q
N
R
--
P
F
R
L
N
G
----
D
N
G
--
E
Y
T
C
-
D
A
L
I
I
A
T
G
A
S
A
R
Y
L
G
L
----
P
S
E
E
A
----
F
K
G
R
G
V
S
A
C
A
T
S
D
G
--
F
--
F
Y
R
N
Q
K
V
A
V
I
G
G
G
N
T
A
V
E
E
A
L
Y
L
S
N
I
A
S
E
V
H
L
I
H
R
R
D
G
F
R
A
E
K
I
L
I
K
R
L
M
D
K
V
---
E
N
G
N
I
I
L
H
T
N
R
T
L
E
E
V
T
G
D
Q
-
M
----
G
V
T
G
V
R
L
R
D
T
Q
N
S
D
N
I
E
S
L
D
V
A
G
L
F
V
A
I
G
H
S
P
N
T
A
I
F
E
G
-----
Q
----
L
E
L
-
E
N
G
Y
I
K
V
Q
S
G
IHGN
A
T
Q
T
S
I
P
G
V
F
A
A
G
D
V
M
D
H
I
--
Y
R
Q
A
I
T
S
A
G
T
G
C
M
A
A
L
D
A
E
R
Y
L
D
G
L
--
30
PsiBlast_CBE
89.85
45%
-110
- C2 -
2WHD
3
?
B:
[31-341]
-------
T
R
V
C
I
I
G
S
G
P
A
A
H
T
A
A
I
Y
A
A
R
A
E
L
K
-
P
V
L
-----
F
--
E
G
WMAND
I
-----
A
-----
A
-----
G
G
Q
L
T
T
T
T
D
V
E
N
F
P
G
F
P
-
T
G
I
-
M
G
I
D
L
M
D
N
C
R
A
Q
S
V
R
F
G
T
N
I
L
S
E
---
T
V
T
E
V
D
F
S
A
--
R
-
P
F
R
V
T
--
S
D
S
T
--
T
V
L
A
-
D
T
V
V
V
A
T
G
A
V
A
R
R
L
Y
F
----
S
G
S
D
T
----
Y
W
N
R
G
I
S
A
C
A
V
C
D
G
--
A
AP
I
F
R
N
K
P
I
A
V
I
G
G
G
D
S
A
M
E
E
G
N
F
L
T
K
Y
G
S
Q
V
Y
I
I
H
R
R
N
T
F
R
A
S
K
---
I
M
Q
A
R
A
L
---
S
N
P
K
I
Q
V
V
W
D
S
E
V
V
E
A
Y
G
G
A
-
G
G
G
--
P
L
A
G
V
K
V
K
N
L
V
-
T
G
E
V
S
D
L
Q
V
S
G
L
F
F
A
I
G
H
E
P
A
T
K
F
L
N
G
-----
Q
----
L
E
L
H
A
D
G
Y
V
A
T
K
P
G
----
S
T
H
T
S
V
E
G
V
F
A
A
G
D
V
Q
D
K
K
--
Y
R
Q
A
I
T
A
A
G
S
G
C
M
A
A
L
D
A
E
H
Y
L
Q
E
V
--
10
PsiBlast_PDB
89.50
45%
-110
- C2 -
2WHD
3
?
A:
[31-341]
-------
T
R
V
C
I
I
G
S
G
P
A
A
H
T
A
A
I
Y
A
A
R
A
E
L
K
-
P
V
L
-----
F
--
E
G
WMAND
I
-----
A
-----
A
-----
G
G
Q
L
T
T
T
T
D
V
E
N
F
P
G
F
P
-
T
G
I
-
M
G
I
D
L
M
D
N
C
R
A
Q
S
V
R
F
G
T
N
I
L
S
E
---
T
V
T
E
V
D
F
S
A
--
R
-
P
F
R
V
T
--
S
D
S
T
--
T
V
L
A
-
D
T
V
V
V
A
T
G
A
V
A
R
R
L
Y
F
----
S
G
S
D
T
----
Y
W
N
R
G
I
S
A
C
A
V
C
D
G
--
A
AP
I
F
R
N
K
P
I
A
V
I
G
G
G
D
S
A
M
E
E
G
N
F
L
T
K
Y
G
S
Q
V
Y
I
I
H
R
R
N
T
F
R
A
S
K
---
I
M
Q
A
R
A
L
---
S
N
P
K
I
Q
V
V
W
D
S
E
V
V
E
A
Y
G
G
A
-
G
G
G
--
P
L
A
G
V
K
V
K
N
L
V
-
T
G
E
V
S
D
L
Q
V
S
G
L
F
F
A
I
G
H
E
P
A
T
K
F
L
N
G
-----
Q
----
L
E
L
H
A
D
G
Y
V
A
T
K
P
G
----
S
T
H
T
S
V
E
G
V
F
A
A
G
D
V
Q
D
K
K
--
Y
R
Q
A
I
T
A
A
G
S
G
C
M
A
A
L
D
A
E
H
Y
L
Q
E
V
--
28
PsiBlast_CBE
89.32
46%
-111
- C2 -
3D8X
2
TRXB1_YEAST
B:
[12-322]
--------
K
V
T
I
I
G
S
G
P
A
A
H
T
A
A
I
Y
L
A
R
A
E
I
K
-
P
I
L
-----
Y
--
E
G
-----
M
-----
M
-----
A
NGIAA
G
G
Q
L
T
T
T
T
E
I
E
N
F
P
G
F
P
-
D
G
L
-
T
G
S
E
L
M
D
R
M
R
E
Q
S
T
K
F
G
T
E
I
I
T
E
T
V
S
K
V
D
L
--
S
S
K
--
P
F
K
L
W
T
E
--
F
N
E
D
AE
P
V
T
T
-
D
A
I
I
L
A
T
G
A
S
A
K
R
M
H
L
----
P
G
E
E
T
----
Y
W
Q
K
G
I
S
A
C
A
V
C
D
G
--
A
VP
I
F
R
N
K
P
L
A
V
I
G
G
G
D
S
A
C
E
E
A
Q
F
L
T
K
Y
G
S
K
V
F
M
L
V
R
K
D
H
L
R
A
S
T
---
I
M
Q
K
R
A
E
---
K
N
E
K
I
E
I
L
Y
N
T
V
A
L
E
A
K
G
D
G
---
K
--
L
L
N
A
L
R
I
K
N
T
K
-
K
N
E
E
T
D
L
P
V
S
G
L
F
Y
A
I
G
H
T
P
A
T
K
I
V
A
G
-----
Q
----
V
D
T
D
E
A
G
Y
I
K
T
V
P
G
----
S
S
L
T
S
V
P
G
F
F
A
A
G
D
V
Q
D
S
K
--
Y
R
Q
A
I
T
S
A
G
S
G
C
M
A
A
L
D
A
E
K
Y
L
T
S
L
E
-
62
HHSearch
89.28
46%
-108
* C2 *
3ITJ
3
TRXB1_YEAST
A:
[21-337]
-----
V
H
N
K
V
T
I
I
G
S
G
P
A
A
H
T
A
A
I
Y
L
A
R
A
E
I
K
-
P
I
L
-----
Y
--
E
G
-----
M
-----
M
ANGIA
A
-----
G
G
Q
L
T
T
T
T
E
I
E
N
F
P
G
F
P
-
D
G
L
-
T
G
S
E
L
M
D
R
M
R
E
Q
S
T
K
F
G
T
E
I
I
T
E
T
V
S
K
V
D
L
--
S
S
K
--
P
F
K
L
W
T
E
FN
E
D
A
E
--
P
V
T
T
-
D
A
I
I
L
A
T
G
A
S
A
K
R
M
H
L
----
P
G
E
E
T
----
Y
W
Q
K
G
I
S
A
C
A
V
C
D
G
--
A
VP
I
F
R
N
K
P
L
A
V
I
G
G
G
D
S
A
C
E
E
A
Q
F
L
T
K
Y
G
S
K
V
F
M
L
V
R
K
D
H
L
R
A
S
T
---
I
M
Q
K
R
A
E
---
K
N
E
K
I
E
I
L
Y
N
T
V
A
L
E
A
K
G
D
G
-
K
----
L
L
N
A
L
R
I
K
N
T
K
-
K
N
E
E
T
D
L
P
V
S
G
L
F
Y
A
I
G
H
T
P
A
T
K
I
V
A
G
-----
Q
----
V
D
T
D
E
A
G
Y
I
K
T
V
P
G
----
S
S
L
T
S
V
P
G
F
F
A
A
G
D
V
Q
D
S
K
--
Y
R
Q
A
I
T
S
A
G
S
G
C
M
A
A
L
D
A
E
K
Y
L
T
S
L
--
67
HHSearch
89.07
48%
-106
- C2 -
2A87
5
TRXB_MYCTU
A:
[10-318]
--
A
H
H
P
V
R
D
V
I
V
I
G
S
G
P
A
G
Y
T
A
A
L
Y
A
A
R
A
Q
L
A
-
P
L
V
-----
F
--
E
G
-----
T
-----
S
-----
F
-----
G
G
A
L
M
T
T
T
D
V
E
N
Y
P
G
F
R
N
G
-
I
-
T
G
P
E
L
M
D
E
M
R
E
Q
A
L
R
F
G
A
D
L
R
M
E
D
V
E
S
V
S
L
--
H
G
P
--
L
K
S
V
V
T
---
A
D
G
Q
--
T
H
R
A
-
R
A
V
I
L
A
M
G
A
A
A
R
Y
L
Q
V
----
P
G
E
Q
E
----
L
L
G
R
G
V
S
S
C
A
T
C
D
G
--
F
--
F
F
R
D
Q
D
I
A
V
I
G
G
G
D
S
A
M
E
E
A
T
F
L
T
R
F
A
R
S
V
T
L
V
H
R
R
D
E
F
R
A
S
K
---
I
M
L
D
R
A
R
---
N
N
D
K
I
R
F
L
T
N
H
T
V
V
A
V
D
G
D
T
------
T
V
T
G
L
R
V
R
D
T
N
-
T
G
A
E
T
T
L
P
V
T
G
V
F
V
A
I
G
H
E
P
R
S
G
L
V
R
E
-----
A
----
I
D
V
D
P
D
G
Y
V
L
V
Q
G
R
----
T
T
S
T
S
L
P
G
V
F
A
A
G
D
L
V
D
R
T
--
Y
R
Q
A
V
T
A
A
G
S
G
C
A
A
A
I
D
A
E
R
W
L
A
E
H
A
A
27
PsiBlast_CBE
88.89
46%
-109
- C2 -
3ITJ
4
TRXB1_YEAST
B:
[24-334]
--------
K
V
T
I
I
G
S
G
P
A
A
H
T
A
A
I
Y
L
A
R
A
E
I
K
-
P
I
L
-----
Y
--
E
G
-----
M
-----
M
-----
A
NGIAA
G
G
Q
L
T
T
T
T
E
I
E
N
F
P
G
F
P
-
D
G
L
-
T
G
S
E
L
M
D
R
M
R
E
Q
S
T
K
F
G
T
E
I
I
T
E
T
V
S
K
V
D
L
--
S
S
K
--
P
F
K
L
W
T
E
--
F
N
E
D
A
E
P
V
T
T
-
D
A
I
I
L
A
T
G
A
S
A
K
R
M
H
L
----
P
G
E
E
T
----
Y
W
Q
K
G
I
S
A
C
A
V
C
D
G
--
A
VP
I
F
R
N
K
P
L
A
V
I
G
G
G
D
S
A
C
E
E
A
Q
F
L
T
K
Y
G
S
K
V
F
M
L
V
R
K
D
H
L
R
A
S
T
---
I
M
Q
K
R
A
E
---
K
N
E
K
I
E
I
L
Y
N
T
V
A
L
E
A
K
G
D
G
---
K
--
L
L
N
A
L
R
I
K
N
T
K
-
K
N
E
E
T
D
L
P
V
S
G
L
F
Y
A
I
G
H
T
P
A
T
K
I
V
A
G
-----
Q
----
V
D
T
D
E
A
G
Y
I
K
T
V
P
G
----
S
S
L
T
S
V
P
G
F
F
A
A
G
D
V
Q
D
S
K
--
Y
R
Q
A
I
T
S
A
G
S
G
C
M
A
A
L
D
A
E
K
Y
L
T
S
L
E
-
6
PsiBlast_PDB
88.63
46%
-109
- C2 -
3ITJ
3
TRXB1_YEAST
A:
[24-334]
--------
K
V
T
I
I
G
S
G
P
A
A
H
T
A
A
I
Y
L
A
R
A
E
I
K
-
P
I
L
-----
Y
--
E
G
-----
M
-----
M
-----
A
NGIAA
G
G
Q
L
T
T
T
T
E
I
E
N
F
P
G
F
P
-
D
G
L
-
T
G
S
E
L
M
D
R
M
R
E
Q
S
T
K
F
G
T
E
I
I
T
E
T
V
S
K
V
D
L
--
S
S
K
--
P
F
K
L
W
T
E
--
F
N
E
D
AE
P
V
T
T
-
D
A
I
I
L
A
T
G
A
S
A
K
R
M
H
L
----
P
G
E
E
T
----
Y
W
Q
K
G
I
S
A
C
A
V
C
D
G
--
A
VP
I
F
R
N
K
P
L
A
V
I
G
G
G
D
S
A
C
E
E
A
Q
F
L
T
K
Y
G
S
K
V
F
M
L
V
R
K
D
H
L
R
A
S
T
---
I
M
Q
K
R
A
E
---
K
N
E
K
I
E
I
L
Y
N
T
V
A
L
E
A
K
G
D
G
---
K
--
L
L
N
A
L
R
I
K
N
T
K
-
K
N
E
E
T
D
L
P
V
S
G
L
F
Y
A
I
G
H
T
P
A
T
K
I
V
A
G
-----
Q
----
V
D
T
D
E
A
G
Y
I
K
T
V
P
G
----
S
S
L
T
S
V
P
G
F
F
A
A
G
D
V
Q
D
S
K
--
Y
R
Q
A
I
T
S
A
G
S
G
C
M
A
A
L
D
A
E
K
Y
L
T
S
L
--
26
PsiBlast_CBE
88.59
46%
-106
- C2 -
3ITJ
4
TRXB1_YEAST
C:
[24-334]
--------
K
V
T
I
I
G
S
G
P
A
A
H
T
A
A
I
Y
L
A
R
A
E
I
K
-
P
I
L
-----
Y
--
E
G
-----
M
-----
M
-----
A
NGIAA
G
G
Q
L
T
T
T
T
E
I
E
N
F
P
G
F
P
-
D
G
L
-
T
G
S
E
L
M
D
R
M
R
E
Q
S
T
K
F
G
T
E
I
I
T
E
T
V
S
K
V
D
L
--
S
S
K
--
P
F
K
L
W
T
E
--
F
N
E
D
AE
P
V
T
T
-
D
A
I
I
L
A
T
G
A
S
A
K
R
M
H
L
----
P
G
E
E
T
----
Y
W
Q
K
G
I
S
A
C
A
V
C
D
G
--
A
V--
F
R
N
K
P
L
A
V
I
G
G
G
D
S
A
C
E
E
A
Q
F
L
T
K
Y
G
S
K
V
F
M
L
V
R
K
D
H
L
R
A
S
T
------
K
R
A
E
---
K
N
E
K
I
E
I
L
Y
N
T
V
A
L
E
A
K
G
D
G
---
K
--
L
L
N
A
L
R
I
K
N
T
K
-
K
N
E
E
T
D
L
P
V
S
G
L
F
Y
A
I
G
H
T
P
A
T
K
I
V
A
G
-----
Q
----
V
D
T
D
E
A
G
Y
I
K
T
V
P
G
----
S
S
L
T
S
V
P
G
F
F
A
A
G
D
V
Q
D
S
K
--
Y
R
Q
A
I
T
S
A
G
S
G
C
M
A
A
L
D
A
E
K
Y
L
T
S
L
--
7
PsiBlast_PDB
88.42
46%
-112
- C2 -
3D8X
3
TRXB1_YEAST
A:
[12-322]
--------
K
V
T
I
I
G
S
G
P
A
A
H
T
A
A
I
Y
L
A
R
A
E
I
K
-
P
I
L
-----
Y
--
E
G
-----
M
-----
M
-----
A
NGIAA
G
G
Q
L
T
T
T
T
E
I
E
N
F
P
G
F
P
-
D
G
L
-
T
G
S
E
L
M
D
R
M
R
E
Q
S
T
K
F
G
T
E
I
I
T
E
T
V
S
K
V
D
L
--
S
S
K
--
P
F
K
L
W
T
E
--
F
N
E
D
AE
P
V
T
T
-
D
A
I
I
L
A
T
G
A
S
A
K
R
M
H
L
----
P
G
E
E
T
----
Y
W
Q
K
G
I
S
A
C
A
V
C
D
G
--
A
VP
I
F
R
N
K
P
L
A
V
I
G
G
G
D
S
A
C
E
E
A
Q
F
L
T
K
Y
G
S
K
V
F
M
L
V
R
K
D
H
L
R
A
S
T
---
I
M
Q
K
R
A
E
---
K
N
E
K
I
E
I
L
Y
N
T
V
A
L
E
A
K
G
D
G
---
K
--
L
L
N
A
L
R
I
K
N
T
K
-
K
N
E
E
T
D
L
P
V
S
G
L
F
Y
A
I
G
H
T
P
A
T
K
I
V
A
G
-----
Q
----
V
D
T
D
E
A
G
Y
I
K
T
V
P
G
----
S
S
L
T
S
V
P
G
F
F
A
A
G
D
V
Q
D
S
K
--
Y
R
Q
A
I
T
S
A
G
S
G
C
M
A
A
L
D
A
E
K
Y
L
T
S
L
E
-
5
PsiBlast_PDB
87.13
48%
-107
- C2 -
2A87
5
TRXB_MYCTU
A:
[16-315]
--------
D
V
I
V
I
G
S
G
P
A
G
Y
T
A
A
L
Y
A
A
R
A
Q
L
A
-
P
L
V
-----
F
--
E
G
-----
T
-----
S
-----
F
-----
G
G
A
L
M
T
T
T
D
V
E
N
Y
P
G
F
R
-
N
G
I
-
T
G
P
E
L
M
D
E
M
R
E
Q
A
L
R
F
G
A
D
L
---
R
M
E
D
V
E
S
V
S
L
H
G
--
P
L
K
S
V
V
T
--
A
D
G
Q
--
T
H
R
A
-
R
A
V
I
L
A
M
G
A
A
A
R
Y
L
Q
V
----
P
G
E
Q
E
----
L
L
G
R
G
V
S
S
C
A
T
C
D
G
--
F
--
F
F
R
D
Q
D
I
A
V
I
G
G
G
D
S
A
M
E
E
A
T
F
L
T
R
F
A
R
S
V
T
L
V
H
R
R
D
E
F
R
A
S
K
---
I
M
L
D
R
A
R
---
N
N
D
K
I
R
F
L
T
N
H
T
V
V
A
V
D
G
D
----
T
--
T
V
T
G
L
R
V
R
D
T
N
-
T
G
A
E
T
T
L
P
V
T
G
V
F
V
A
I
G
H
E
P
R
S
G
L
V
R
E
-----
A
----
I
D
V
D
P
D
G
Y
V
L
V
Q
G
R
----
T
T
S
T
S
L
P
G
V
F
A
A
G
D
L
V
D
R
T
--
Y
R
Q
A
V
T
A
A
G
S
G
C
A
A
A
I
D
A
E
R
W
L
A
E
H
A
A
24
PsiBlast_CBE
87.01
48%
-106
- C2 -
2A87
5
TRXB_MYCTU
B:
[16-315]
--------
D
V
I
V
I
G
S
G
P
A
G
Y
T
A
A
L
Y
A
A
R
A
Q
L
A
-
P
L
V
-----
F
--
E
G
-----
T
-----
S
-----
F
-----
G
G
A
L
M
T
T
T
D
V
E
N
Y
P
G
F
R
-
N
G
I
-
T
G
P
E
L
M
D
E
M
R
E
Q
A
L
R
F
G
A
D
L
---
R
M
E
D
V
E
S
V
S
L
H
G
--
P
L
K
S
V
V
T
--
A
D
G
Q
--
T
H
R
A
-
R
A
V
I
L
A
M
G
A
A
A
R
Y
L
Q
V
----
P
G
E
Q
E
----
L
L
G
R
G
V
S
S
C
A
T
C
D
G
--
F
--
F
F
R
D
Q
D
I
A
V
I
G
G
G
D
S
A
M
E
E
A
T
F
L
T
R
F
A
R
S
V
T
L
V
H
R
R
D
E
F
R
A
S
K
---
I
M
L
D
R
A
R
---
N
N
D
K
I
R
F
L
T
N
H
T
V
V
A
V
D
G
D
----
T
--
T
V
T
G
L
R
V
R
D
T
N
-
T
G
A
E
T
T
L
P
V
T
G
V
F
V
A
I
G
H
E
P
R
S
G
L
V
R
E
-----
A
----
I
D
V
D
P
D
G
Y
V
L
V
Q
G
R
----
T
T
S
T
S
L
P
G
V
F
A
A
G
D
L
V
D
R
T
--
Y
R
Q
A
V
T
A
A
G
S
G
C
A
A
A
I
D
A
E
R
W
L
A
E
H
--
68
HHSearch
87.00
44%
-108
- C2 -
2Q7V
2
?
A:
[4-314]
--
P
T
A
H
D
Y
D
V
V
I
I
G
G
G
P
A
G
L
T
A
A
I
Y
T
G
R
A
Q
L
S
-
T
L
I
-----
L
--
E
K
-----
G
-----
M
-----
P
-----
G
G
Q
I
A
W
S
E
E
V
E
N
F
P
G
F
P
-
E
P
I
-
A
G
M
E
L
A
Q
R
M
H
Q
Q
A
E
K
F
G
A
K
V
E
M
D
E
V
Q
G
V
Q
H
D
A
T
S
H
PY
P
F
T
V
R
G
----
Y
N
G
--
E
Y
R
A
-
K
A
V
I
L
A
T
G
A
D
P
R
K
L
G
I
----
P
G
E
D
N
----
F
W
G
K
G
V
S
T
C
A
T
C
D
G
--
F
--
F
Y
K
G
K
K
V
V
V
I
G
G
G
D
A
A
V
E
E
G
M
F
L
T
K
F
A
D
E
V
T
V
I
H
R
R
D
T
L
R
A
N
K
---
V
A
Q
A
R
A
F
---
A
N
P
K
M
K
F
I
W
D
T
A
V
E
E
I
Q
G
A
D
------
S
V
S
G
V
K
L
R
N
L
K
-
T
G
E
V
S
E
L
A
T
D
G
V
F
I
F
I
G
H
V
P
N
T
A
F
V
K
D
-----
T
----
V
S
L
R
D
D
G
Y
V
D
V
R
D
-----
E
I
Y
T
N
I
P
M
L
F
A
A
G
D
V
S
D
Y
I
--
Y
R
Q
L
A
T
S
V
G
A
G
T
R
A
A
M
M
T
E
R
Q
L
A
A
L
--
25
PsiBlast_CBE
86.26
46%
-111
- C2 -
3ITJ
2
TRXB1_YEAST
D:
[24-334]
--------
K
V
T
I
I
G
S
G
P
A
A
H
T
A
A
I
Y
L
A
R
A
E
I
K
-
P
I
L
-----
Y
--
E
G
-----
M
-----
M
-----
A
NGIAA
G
G
Q
L
T
T
T
T
E
I
E
N
F
P
G
F
P
-
D
G
L
-
T
G
S
E
L
M
D
R
M
R
E
Q
S
T
K
F
G
T
E
I
I
T
E
T
V
S
K
V
D
L
--
S
S
K
--
P
F
K
L
W
T
E
--
F
N
E
D
A
E
P
V
T
T
-
D
A
I
I
L
A
T
G
A
S
A
K
R
M
H
L
----
P
G
E
E
T
----
Y
W
Q
K
G
I
S
A
C
A
V
C
D
G
--
A
VP
I
F
R
N
K
P
L
A
V
I
G
G
G
D
S
A
C
E
E
A
Q
F
L
T
K
Y
G
S
K
V
F
M
L
V
R
K
D
H
L
R
A
---------
R
A
E
---
K
N
E
K
I
E
I
L
Y
N
T
V
A
L
E
A
K
G
---------
L
N
A
L
R
I
K
N
T
K
-
K
N
E
E
T
D
L
P
V
S
G
L
F
Y
A
I
G
H
T
P
A
T
K
I
V
A
G
-----
Q
----
V
D
T
D
E
A
G
Y
I
K
T
V
P
G
----
S
S
L
T
S
V
P
G
F
F
A
A
G
D
V
Q
D
S
K
--
Y
R
Q
A
I
T
S
A
G
S
G
C
M
A
A
L
D
A
E
K
Y
L
T
S
L
--
16
PsiBlast_PDB
86.23
43%
-113
- C2 -
4CCR
3
?
A:
[7-312]
---------
V
V
I
I
G
S
G
P
A
A
H
T
A
A
I
Y
L
G
R
S
S
L
K
-
P
V
M
YEGFM
A
--
G
G
-----
V
-----
A
-----
A
-----
G
G
Q
L
T
T
T
T
I
I
E
N
F
P
G
F
P
-
N
G
I
-
D
G
N
E
L
M
M
N
M
R
T
Q
S
E
K
Y
G
T
T
I
I
T
E
---
T
I
D
H
V
D
F
S
T
--
Q
P
F
K
L
F
T
--
E
E
G
K
--
E
V
L
T
-
K
S
V
I
I
A
T
G
A
T
A
K
R
M
H
V
----
P
G
E
D
K
----
Y
W
Q
N
G
V
S
A
C
A
I
C
D
G
--
A
VP
I
F
R
N
K
V
L
M
V
V
G
G
G
D
A
A
M
E
E
A
L
H
L
T
K
Y
G
S
K
V
I
I
L
H
R
R
D
A
F
R
--
K
---
T
M
Q
E
R
V
L
---
N
H
P
K
I
E
V
I
W
N
S
E
L
V
E
L
E
G
D
G
-
D
----
L
L
N
G
A
K
I
H
N
L
V
-
S
G
E
Y
K
V
V
P
V
A
G
L
F
Y
A
I
G
H
S
P
N
S
K
F
L
G
G
-----
Q
----
V
K
T
A
D
D
G
Y
I
L
T
E
------
G
P
K
T
S
V
D
G
V
F
A
C
G
D
V
C
D
R
V
--
Y
R
Q
A
I
V
A
A
G
S
G
C
M
A
A
L
S
C
E
K
W
L
Q
T
H
--
35
PsiBlast_CBE
86.17
43%
-111
- C2 -
4CBQ
8
?
B:
[7-312]
---------
V
V
I
I
G
S
G
P
A
A
H
T
A
A
I
Y
L
G
R
S
S
L
K
-
P
V
M
YEGFM
A
--
G
G
-----
V
-----
A
-----
A
-----
G
G
Q
L
T
T
T
T
I
I
E
N
F
P
G
F
P
-
N
G
I
-
D
G
N
E
L
M
M
N
M
R
T
Q
S
E
K
Y
G
T
T
I
I
T
E
---
T
I
D
H
V
D
F
S
T
--
Q
P
F
K
L
F
T
--
E
E
G
K
--
E
V
L
T
-
K
S
V
I
I
A
T
G
A
T
A
K
R
M
H
V
----
P
G
E
D
K
----
Y
W
Q
N
G
V
S
A
C
A
I
C
D
G
--
A
VP
I
F
R
N
K
V
L
M
V
V
G
G
G
D
A
A
M
E
E
A
L
H
L
T
K
Y
G
S
K
V
I
I
L
H
R
R
D
A
F
R
A
S
K
---
T
M
Q
E
R
V
L
---
N
H
P
K
I
E
V
I
W
N
S
E
L
V
E
L
E
G
D
G
-
D
----
L
L
N
G
A
K
I
H
N
L
V
-
S
G
E
Y
K
V
V
P
V
A
G
L
F
Y
A
I
G
H
S
P
N
S
K
F
L
G
G
-----
Q
----
V
K
T
A
D
D
G
Y
I
L
T
E
------
G
P
K
T
S
V
D
G
V
F
A
C
G
D
V
C
D
R
V
--
Y
R
Q
A
I
V
A
A
G
S
G
C
M
A
A
L
S
C
E
K
W
L
Q
T
H
--
17
PsiBlast_PDB
85.77
43%
-114
- C2 -
4UP3
4
?
A:
[7-312]
---------
V
V
I
I
G
S
G
P
A
A
H
T
A
A
I
Y
L
G
R
S
S
L
K
-
P
V
M
YEGFM
A
--
G
G
-----
V
-----
A
-----
A
-----
G
G
Q
L
T
T
T
T
I
I
E
N
F
P
G
F
P
-
N
G
I
-
D
G
N
E
L
M
M
N
M
R
T
Q
S
E
K
Y
G
T
T
I
I
T
E
---
T
I
D
H
V
D
F
S
T
--
Q
P
F
K
L
F
T
--
E
E
G
K
--
E
V
L
T
-
K
S
V
I
I
A
T
G
A
T
A
K
R
M
H
V
----
P
G
E
D
K
----
Y
W
Q
N
G
V
S
A
S
A
I
C
D
G
--
A
VP
I
F
R
N
K
V
L
M
V
V
G
G
G
D
A
A
M
E
E
A
L
H
L
T
K
Y
G
S
K
V
I
I
L
H
R
R
D
A
F
R
A
S
K
---
T
M
Q
E
R
V
L
---
N
H
P
K
I
E
V
I
W
N
S
E
L
V
E
L
E
G
D
G
-
D
----
L
L
N
G
A
K
I
H
N
L
V
-
S
G
E
Y
K
V
V
P
V
A
G
L
F
Y
A
I
G
H
S
P
N
S
K
F
L
G
G
-----
Q
----
V
K
T
A
D
D
G
Y
I
L
T
E
------
G
P
K
T
S
V
D
G
V
F
A
C
G
D
V
Q
D
R
V
--
Y
R
Q
A
I
V
A
A
G
S
G
C
M
A
A
L
S
C
E
K
W
L
Q
T
H
--
38
PsiBlast_CBE
85.59
43%
-111
- C2 -
4UP3
4
?
B:
[7-312]
---------
V
V
I
I
G
S
G
P
A
A
H
T
A
A
I
Y
L
G
R
S
S
L
K
-
P
V
M
YEGFM
A
--
G
G
-----
V
-----
A
-----
A
-----
G
G
Q
L
T
T
T
T
I
I
E
N
F
P
G
F
P
-
N
G
I
-
D
G
N
E
L
M
M
N
M
R
T
Q
S
E
K
Y
G
T
T
I
I
T
E
---
T
I
D
H
V
D
F
S
T
--
Q
P
F
K
L
F
T
--
E
E
G
K
--
E
V
L
T
-
K
S
V
I
I
A
T
G
A
T
A
K
R
M
H
V
----
P
G
E
D
K
----
Y
W
Q
N
G
V
S
A
S
A
I
C
D
G
--
A
VP
I
F
R
N
K
V
L
M
V
V
G
G
G
D
A
A
M
E
E
A
L
H
L
T
K
Y
G
S
K
V
I
I
L
H
R
R
D
A
F
R
A
S
K
---
T
M
Q
E
R
V
L
---
N
H
P
K
I
E
V
I
W
N
S
E
L
V
E
L
E
G
D
G
-
D
----
L
L
N
G
A
K
I
H
N
L
V
-
S
G
E
Y
K
V
V
P
V
A
G
L
F
Y
A
I
G
H
S
P
N
S
K
F
L
G
G
-----
Q
----
V
K
T
A
D
D
G
Y
I
L
T
E
------
G
P
K
T
S
V
D
G
V
F
A
C
G
D
V
Q
D
R
V
--
Y
R
Q
A
I
V
A
A
G
S
G
C
M
A
A
L
S
C
E
K
W
L
Q
T
H
--
36
PsiBlast_CBE
85.35
43%
-112
- C2 -
4A65
6
?
B:
[7-312]
---------
V
V
I
I
G
S
G
P
A
A
H
T
A
A
I
Y
L
G
R
S
S
L
K
-
P
V
M
YEGFM
A
--
G
G
-----
V
-----
A
-----
A
-----
G
G
Q
L
T
T
T
T
I
I
E
N
F
P
G
F
P
-
N
G
I
-
D
G
N
E
L
M
M
N
M
R
T
Q
S
E
K
Y
G
T
T
I
I
T
E
---
T
I
D
H
V
D
F
S
T
--
Q
P
F
K
L
F
T
--
E
E
G
K
--
E
V
L
T
-
K
S
V
I
I
A
T
G
A
T
A
K
R
M
H
V
----
P
G
E
D
K
----
Y
W
Q
N
G
V
S
A
C
A
I
C
D
G
--
A
VP
I
F
R
N
K
V
L
M
V
V
G
G
G
D
A
A
M
E
E
A
L
H
L
T
K
Y
G
S
K
V
I
I
L
H
R
R
D
A
F
R
A
S
K
---
T
M
Q
E
R
V
L
---
N
H
P
K
I
E
V
I
W
N
S
E
L
V
E
L
E
G
D
G
-
D
----
L
L
N
G
A
K
I
H
N
L
V
-
S
G
E
Y
K
V
V
P
V
A
G
L
F
Y
A
I
G
H
S
P
N
S
K
F
L
G
G
-----
Q
----
V
K
T
A
D
D
G
Y
I
L
T
E
------
G
P
K
T
S
V
D
G
V
F
A
C
G
D
V
C
D
R
V
--
Y
R
Q
A
I
V
A
A
G
S
G
C
M
A
A
L
S
C
E
K
W
L
Q
T
H
--
37
PsiBlast_CBE
85.33
43%
-115
- C2 -
4A5L
3
?
B:
[7-312]
---------
V
V
I
I
G
S
G
P
A
A
H
T
A
A
I
Y
L
G
R
S
S
L
K
-
P
V
M
YEGFM
A
--
G
G
-----
V
-----
A
-----
A
-----
G
G
Q
L
T
T
T
T
I
I
E
N
F
P
G
F
P
-
N
G
I
-
D
G
N
E
L
M
M
N
M
R
T
Q
S
E
K
Y
G
T
T
I
I
T
E
---
T
I
D
H
V
D
F
S
T
--
Q
P
F
K
L
F
T
--
E
E
G
K
--
E
V
L
T
-
K
S
V
I
I
A
T
G
A
T
A
K
R
M
H
V
----
P
G
E
D
K
----
Y
W
Q
N
G
V
S
A
C
A
I
C
D
G
--
A
VP
I
F
R
N
K
V
L
M
V
V
G
G
G
D
A
A
M
E
E
A
L
H
L
T
K
Y
G
S
K
V
I
I
L
H
R
R
D
A
F
R
A
S
K
---
T
M
Q
E
R
V
L
---
N
H
P
K
I
E
V
I
W
N
S
E
L
V
E
L
E
G
D
G
-
D
----
L
L
N
G
A
K
I
H
N
L
V
-
S
G
E
Y
K
V
V
P
V
A
G
L
F
Y
A
I
G
H
S
P
N
S
K
F
L
G
G
-----
Q
----
V
K
T
A
D
D
G
Y
I
L
T
E
------
G
P
K
T
S
V
D
G
V
F
A
C
G
D
V
C
D
R
V
--
Y
R
Q
A
I
V
A
A
G
S
G
C
M
A
A
L
S
C
E
K
W
L
Q
T
H
--
33
PsiBlast_CBE
85.30
43%
-111
- C2 -
4CCR
3
?
B:
[7-312]
---------
V
V
I
I
G
S
G
P
A
A
H
T
A
A
I
Y
L
G
R
S
S
L
K
-
P
V
M
YEGFM
A
--
G
G
-----
V
-----
A
-----
A
-----
G
G
Q
L
T
T
T
T
I
I
E
N
F
P
G
F
P
-
N
G
I
-
D
G
N
E
L
M
M
N
M
R
T
Q
S
E
K
Y
G
T
T
I
I
T
E
---
T
I
D
H
V
D
F
S
T
--
Q
P
F
K
L
F
T
--
E
E
G
K
--
E
V
L
T
-
K
S
V
I
I
A
T
G
A
T
A
K
R
M
H
V
----
P
G
E
D
K
----
Y
W
Q
N
G
V
S
A
C
A
I
C
D
G
--
A
VP
I
F
R
N
K
V
L
M
V
V
G
G
G
D
A
A
M
E
E
A
L
H
L
T
K
Y
G
S
K
V
I
I
L
H
R
R
D
A
F
R
A
S
K
---
T
M
Q
E
R
V
L
---
N
H
P
K
I
E
V
I
W
N
S
E
L
V
E
L
E
G
D
G
-
D
----
L
L
N
G
A
K
I
H
N
L
V
-
S
G
E
Y
K
V
V
P
V
A
G
L
F
Y
A
I
G
H
S
P
N
S
K
F
L
G
G
-----
Q
----
V
K
T
A
D
D
G
Y
I
L
T
E
------
G
P
K
T
S
V
D
G
V
F
A
C
G
D
V
C
D
R
V
--
Y
R
Q
A
I
V
A
A
G
S
G
C
M
A
A
L
S
C
E
K
W
L
Q
T
H
--
14
PsiBlast_PDB
85.05
43%
-115
- C2 -
4CBQ
9
?
A:
[7-312]
---------
V
V
I
I
G
S
G
P
A
A
H
T
A
A
I
Y
L
G
R
S
S
L
K
-
P
V
M
YEGFM
A
--
G
G
-----
V
-----
A
-----
A
-----
G
G
Q
L
T
T
T
T
I
I
E
N
F
P
G
F
P
-
N
G
I
-
D
G
N
E
L
M
M
N
M
R
T
Q
S
E
K
Y
G
T
T
I
I
T
E
---
T
I
D
H
V
D
F
S
T
--
Q
P
F
K
L
F
T
--
E
E
G
K
--
E
V
L
T
-
K
S
V
I
I
A
T
G
A
T
A
K
R
M
H
V
----
P
G
E
D
K
----
Y
W
Q
N
G
V
S
A
C
A
I
C
D
G
--
A
VP
I
F
R
N
K
V
L
M
V
V
G
G
G
D
A
A
M
E
E
A
L
H
L
T
K
Y
G
S
K
V
I
I
L
H
R
R
D
A
F
R
A
S
K
---
T
M
Q
E
R
V
L
---
N
H
P
K
I
E
V
I
W
N
S
E
L
V
E
L
E
G
D
G
-
D
----
L
L
N
G
A
K
I
H
N
L
V
-
S
G
E
Y
K
V
V
P
V
A
G
L
F
Y
A
I
G
H
S
P
N
S
K
F
L
G
G
-----
Q
----
V
K
T
A
D
D
G
Y
I
L
T
E
------
G
P
K
T
S
V
D
G
V
F
A
C
G
D
V
C
D
R
V
--
Y
R
Q
A
I
V
A
A
G
S
G
C
M
A
A
L
S
C
E
K
W
L
Q
T
H
--
34
PsiBlast_CBE
84.79
43%
-110
- C2 -
4CCQ
5
?
B:
[7-312]
---------
V
V
I
I
G
S
G
P
A
A
H
T
A
A
I
Y
L
G
R
S
S
L
K
-
P
V
M
YEGFM
A
--
G
G
-----
V
-----
A
-----
A
-----
G
G
Q
L
T
T
T
T
I
I
E
N
F
P
G
F
P
-
N
G
I
-
D
G
N
E
L
M
M
N
M
R
T
Q
S
E
K
Y
G
T
T
I
I
T
E
---
T
I
D
H
V
D
F
S
T
--
Q
P
F
K
L
F
T
--
E
E
G
K
--
E
V
L
T
-
K
S
V
I
I
A
T
G
A
T
A
K
R
M
H
V
----
P
G
E
D
K
----
Y
W
Q
N
G
V
S
A
C
A
I
C
D
G
--
A
VP
I
F
R
N
K
V
L
M
V
V
G
G
G
D
A
A
M
E
E
A
L
H
L
T
K
Y
G
S
K
V
I
I
L
H
R
R
D
A
F
R
A
S
K
---
T
M
Q
E
R
V
L
---
N
H
P
K
I
E
V
I
W
N
S
E
L
V
E
L
E
G
D
G
-
D
----
L
L
N
G
A
K
I
H
N
L
V
-
S
G
E
Y
K
V
V
P
V
A
G
L
F
Y
A
I
G
H
S
P
N
S
K
F
L
G
G
-----
Q
----
V
K
T
A
D
D
G
Y
I
L
T
E
------
G
P
K
T
S
V
D
G
V
F
A
C
G
D
V
C
D
R
V
--
Y
R
Q
A
I
V
A
A
G
S
G
C
M
A
A
L
S
C
E
K
W
L
Q
T
H
--
15
PsiBlast_PDB
84.33
43%
-112
- C2 -
4CCQ
6
?
A:
[7-312]
---------
V
V
I
I
G
S
G
P
A
A
H
T
A
A
I
Y
L
G
R
S
S
L
K
-
P
V
M
YEGFM
A
--
G
G
-----
V
-----
A
-----
A
-----
G
G
Q
L
T
T
T
T
I
I
E
N
F
P
G
F
P
-
N
G
I
-
D
G
N
E
L
M
M
N
M
R
T
Q
S
E
K
Y
G
T
T
I
I
T
E
---
T
I
D
H
V
D
F
S
T
--
Q
P
F
K
L
F
T
--
E
E
G
K
--
E
V
L
T
-
K
S
V
I
I
A
T
G
A
T
A
K
R
M
H
V
----
P
G
E
D
K
----
Y
W
Q
N
G
V
S
A
C
A
I
C
D
G
--
A
VP
I
F
R
N
K
V
L
M
V
V
G
G
G
D
A
A
M
E
E
A
L
H
L
T
K
Y
G
S
K
V
I
I
L
H
R
R
D
A
F
R
A
S
K
---
T
M
Q
E
R
V
L
---
N
H
P
K
I
E
V
I
W
N
S
E
L
V
E
L
E
G
D
G
-
D
----
L
L
N
G
A
K
I
H
N
L
V
-
S
G
E
Y
K
V
V
P
V
A
G
L
F
Y
A
I
G
H
S
P
N
S
K
F
L
G
G
-----
Q
----
V
K
T
A
D
D
G
Y
I
L
T
E
------
G
P
K
T
S
V
D
G
V
F
A
C
G
D
V
C
D
R
V
--
Y
R
Q
A
I
V
A
A
G
S
G
C
M
A
A
L
S
C
E
K
W
L
Q
T
H
--
53
PsiBlast_CBE
83.47
35%
-119
- C2 -
3F8D
5
?
B:
[18-316]
---------
V
I
I
V
G
L
G
P
A
A
Y
G
A
A
L
Y
S
A
R
Y
M
L
K
-
T
L
V
-----
I
---
G
-----
E
-----
T
-----
P
-----
G
G
Q
L
T
E
A
G
I
V
D
D
Y
L
G
L
I
-
E
-
I
-
Q
A
S
D
M
I
K
V
F
N
K
H
I
E
K
Y
E
V
P
V
L
L
D
I
V
E
K
I
E
N
--
R
-
D
--
E
F
V
V
K
T
K
---
R
K
G
--
E
F
K
A
-
D
S
V
I
L
G
I
G
V
K
R
R
K
L
G
V
----
P
G
E
Q
E
----
F
A
G
R
G
I
S
Y
C
S
V
A
D
A
--
P
--
L
F
K
N
R
V
V
A
V
I
G
G
G
D
S
A
L
E
G
A
E
I
L
S
S
Y
S
T
K
V
Y
L
I
H
R
R
D
T
F
K
A
Q
P
---
I
Y
V
E
T
V
K
---
K
K
P
N
V
E
F
V
L
N
S
V
V
K
E
I
K
G
D
----
K
--
V
V
K
Q
V
V
V
E
N
L
K
-
T
G
E
I
K
E
L
N
V
N
G
V
F
I
E
I
G
F
D
P
P
T
D
F
A
K
S
-----
N
G---
I
E
T
D
T
N
G
Y
I
K
V
D
E
W
----
M
R
-
T
S
V
P
G
V
F
A
A
G
D
C
T
S
A
W
LG
F
R
Q
V
I
T
A
V
A
Q
G
A
V
A
A
T
S
A
Y
R
Y
V
T
E
K
--
65
HHSearch
82.90
37%
-114
- C2 -
2Q0L
2
TRXB_HELPY
A:
[1-311]
------
M
I
D
C
A
I
I
G
G
G
P
A
G
L
S
A
G
L
Y
A
T
R
G
G
V
K
N
A
V
L
-----
F
--
E
K
-----
G
-----
M
-----
P
-----
G
G
Q
I
T
G
S
S
E
I
E
N
Y
P
G
V
K
-
E
V
V
-
S
G
L
D
F
M
Q
P
W
Q
E
Q
C
F
R
F
G
L
K
H
E
M
T
A
V
Q
R
V
S
K
--
K
D
S
--
H
F
V
I
L
A
---
E
D
G
K
--
T
F
E
A
-
K
S
V
I
I
A
T
G
G
S
P
K
R
T
G
I
----
K
G
E
S
E
----
Y
W
G
K
G
V
S
T
C
A
T
C
D
G
--
F
--
F
Y
K
N
K
E
V
A
V
L
G
G
G
D
T
A
V
E
E
A
I
Y
L
A
N
I
C
K
K
V
Y
L
I
H
R
R
D
G
F
R
C
A
P
---
I
T
L
E
H
A
K
---
N
N
D
K
I
E
F
L
T
P
Y
V
V
E
E
I
K
G
D
A
-
S
----
G
V
S
S
L
S
I
K
N
T
A
-
T
N
E
K
R
E
L
V
V
P
G
F
F
I
F
V
G
Y
D
V
N
N
A
V
L
K
Q
E----
D
NSML
C
K
C
D
E
Y
G
S
I
V
V
D
F
-----
S
M
K
T
N
V
Q
G
L
F
A
A
G
D
I
R
I
F
A
--
P
K
Q
V
V
C
A
A
S
D
G
A
T
A
A
L
S
V
I
S
Y
L
E
H
H
--
44
PsiBlast_CBE
82.79
36%
-120
- C2 -
3F8P
4
?
B:
[18-316]
---------
V
I
I
V
G
L
G
P
A
A
Y
G
A
A
L
Y
S
A
R
Y
M
L
K
-
T
L
V
-----
I
---
G
-----
E
-----
T
-----
P
-----
G
G
Q
L
T
E
A
G
I
V
D
D
Y
L
G
L
I
-
E
-
I
-
Q
A
S
D
M
I
K
V
F
N
K
H
I
E
K
Y
E
V
P
V
L
L
D
I
V
E
K
I
E
--------
E
F
V
V
K
T
K
---
R
K
G
--
E
F
K
A
-
D
S
V
I
L
G
I
G
V
K
R
R
K
L
G
V
----
P
G
E
Q
E
----
F
A
G
R
G
I
S
Y
C
S
V
C
D
A
--
P
--
L
F
K
N
R
V
V
A
V
I
G
G
G
D
S
A
L
E
G
A
E
I
L
S
S
Y
S
T
K
V
Y
L
I
H
R
R
D
T
F
K
A
Q
P
---
I
Y
V
E
T
V
K
---
K
K
P
N
V
E
F
V
L
N
S
V
V
K
E
I
K
G
D
----
K
--
V
V
K
Q
V
V
V
E
N
L
K
-
T
G
E
I
K
E
L
N
V
N
G
V
F
I
E
I
G
F
D
P
P
T
D
F
A
K
S
-----
N
G---
I
E
T
D
T
N
G
Y
I
K
V
D
E
W
----
M
R
-
T
S
V
P
G
V
F
A
A
G
D
C
T
S
A
W
LG
F
R
Q
V
I
T
A
V
A
Q
G
A
V
A
A
T
S
A
Y
R
Y
V
T
E
K
--
50
PsiBlast_CBE
81.38
36%
-116
- C2 -
2Q0K
3
TRXB_HELPY
B:
[6-309]
-----------
I
I
G
G
G
P
A
G
L
S
A
G
L
Y
A
T
R
G
G
V
K
-
N
A
V
-----
L
FE
K
G
-----
M
-----------
P
-----
G
G
Q
I
T
G
S
S
E
I
E
N
Y
P
G
V
K
-
E
-
V
V
S
G
L
D
F
M
Q
P
W
Q
E
Q
C
F
R
F
G
---
L
K
H
E
M
T
A
V
Q
R
V
S
K
K
D
--
S
H
F
V
I
L
A
--
E
D
G
K
--
T
F
E
A
-
K
S
V
I
I
A
T
G
G
S
P
K
R
T
G
I
----
K
G
E
S
E
----
Y
W
G
K
G
V
S
T
C
A
T
C
D
G
--
F
--
F
Y
K
N
K
E
V
A
V
L
G
G
G
D
T
A
V
E
E
A
I
Y
L
A
N
I
C
K
K
V
Y
L
I
H
R
R
D
G
F
R
C
A
P
---
I
T
L
E
H
A
K
---
N
N
D
K
I
E
F
L
T
P
Y
V
V
E
E
I
K
G
D
A
-
S
----
G
V
S
S
L
S
I
K
N
T
A
-
T
N
E
K
R
E
L
V
V
P
G
F
F
I
F
V
G
Y
D
V
N
N
A
V
L
K
Q
EDNSM
L
----
C
K
C
D
E
Y
G
S
I
V
V
D
F
-----
S
M
K
T
N
V
Q
G
L
F
A
A
G
D
I
R
I
F
A
--
P
K
Q
V
V
C
A
A
S
D
G
A
T
A
A
L
S
V
I
S
Y
L
E
H
---
49
PsiBlast_CBE
80.50
36%
-115
- C2 -
2Q0L
2
TRXB_HELPY
A:
[6-309]
-----------
I
I
G
G
G
P
A
G
L
S
A
G
L
Y
A
T
R
G
G
V
K
-
N
A
V
-----
L
F
E
K
G
-----
M
-----------
P
-----
G
G
Q
I
T
G
S
S
E
I
E
N
Y
P
G
V
K
-
E
-
V
V
S
G
L
D
F
M
Q
P
W
Q
E
Q
C
F
R
F
G
---
L
K
H
E
M
T
A
V
Q
R
V
S
K
K
D
--
S
H
F
V
I
L
A
--
E
D
G
K
--
T
F
E
A
-
K
S
V
I
I
A
T
G
G
S
P
K
R
T
G
I
----
K
G
E
S
E
----
Y
W
G
K
G
V
S
T
C
A
T
C
D
G
--
F
--
F
Y
K
N
K
E
V
A
V
L
G
G
G
D
T
A
V
E
E
A
I
Y
L
A
N
I
C
K
K
V
Y
L
I
H
R
R
D
G
F
R
C
A
P
---
I
T
L
E
H
A
K
---
N
N
D
K
I
E
F
L
T
P
Y
V
V
E
E
I
K
G
D
A
-
S
----
G
V
S
S
L
S
I
K
N
T
A
-
T
N
E
K
R
E
L
V
V
P
G
F
F
I
F
V
G
Y
D
V
N
N
A
V
L
K
Q
EDNSM
L
----
C
K
C
D
E
Y
G
S
I
V
V
D
F
-----
S
M
K
T
N
V
Q
G
L
F
A
A
G
D
I
R
I
F
A
--
P
K
Q
V
V
C
A
A
S
D
G
A
T
A
A
L
S
V
I
S
Y
L
E
H
H
--
48
PsiBlast_CBE
80.22
36%
-117
- C2 -
2Q0L
2
TRXB_HELPY
B:
[6-309]
-----------
I
I
G
G
G
P
A
G
L
S
A
G
L
Y
A
T
R
G
G
V
K
-
N
A
V
-----
L
FE
K
G
-----
M
-----------
P
-----
G
G
Q
I
T
G
S
S
E
I
E
N
Y
P
G
V
K
-
E
-
V
V
S
G
L
D
F
M
Q
P
W
Q
E
Q
C
F
R
F
G
---
L
K
H
E
M
T
A
V
Q
R
V
S
K
K
D
--
S
H
F
V
I
L
A
--
E
D
G
K
--
T
F
E
A
-
K
S
V
I
I
A
T
G
G
S
P
K
R
T
G
I
----
K
G
E
S
E
----
Y
W
G
K
G
V
S
T
C
A
T
C
D
G
--
F
--
F
Y
K
N
K
E
V
A
V
L
G
G
G
D
T
A
V
E
E
A
I
Y
L
A
N
I
C
K
K
V
Y
L
I
H
R
R
D
G
F
R
C
A
P
---
I
T
L
E
H
A
K
---
N
N
D
K
I
E
F
L
T
P
Y
V
V
E
E
I
K
G
D
A
-
S
----
G
V
S
S
L
S
I
K
N
T
A
-
T
N
E
K
R
E
L
V
V
P
G
F
F
I
F
V
G
Y
D
V
N
N
A
V
L
K
Q
EDNSM
L
----
C
K
C
D
E
Y
G
S
I
V
V
D
F
-----
S
M
K
T
N
V
Q
G
L
F
A
A
G
D
I
R
I
F
A
--
P
K
Q
V
V
C
A
A
S
D
G
A
T
A
A
L
S
V
I
S
Y
L
E
H
H
--
20
PsiBlast_PDB
79.58
36%
-118
- C2 -
2Q0K
3
TRXB_HELPY
A:
[6-309]
-----------
I
I
G
G
G
P
A
G
L
S
A
G
L
Y
A
T
R
G
G
V
K
-
N
A
V
-----
L
F
E
K
G
-----
M
-----------
P
-----
G
G
Q
I
T
G
S
S
E
I
E
N
Y
P
G
V
K
-
E
-
V
V
S
G
L
D
F
M
Q
P
W
Q
E
Q
C
F
R
F
G
---
L
K
H
E
M
T
A
V
Q
R
V
S
K
K
D
--
S
H
F
V
I
L
A
--
E
D
G
K
--
T
F
E
A
-
K
S
V
I
I
A
T
G
G
S
P
K
R
T
G
I
----
K
G
E
S
E
----
Y
W
G
K
G
V
S
T
C
A
T
C
D
G
--
F
--
F
Y
K
N
K
E
V
A
V
L
G
G
G
D
T
A
V
E
E
A
I
Y
L
A
N
I
C
K
K
V
Y
L
I
H
R
R
D
G
F
R
C
A
P
---
I
T
L
E
H
A
K
---
N
N
D
K
I
E
F
L
T
P
Y
V
V
E
E
I
K
G
D
A
-
S
----
G
V
S
S
L
S
I
K
N
T
A
-
T
N
E
K
R
E
L
V
V
P
G
F
F
I
F
V
G
Y
D
V
N
N
A
V
L
K
Q
EDNSM
L
----
C
K
C
D
E
Y
G
S
I
V
V
D
F
-----
S
M
K
T
N
V
Q
G
L
F
A
A
G
D
I
R
I
F
A
--
P
K
Q
V
V
C
A
A
S
D
G
A
T
A
A
L
S
V
I
S
Y
L
E
H
---