@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Wbm0644: (2015-12-03 )
MLKKYLKAAIYLSLLIYIYISVFSYSYKDISLNTVTDKEVTNLGGIVGSYLADILVQFLGLTSITVATTIICFLIFRPSKRLLKVLYSVLINLGICAMLPQLSLGITARYMHSGIIGNILINNCPFYIFIIATSTGIVGLIGWKRTIYLLFLLYKKVASLLAKVLFFRLYKAAEYPTPPLVVEEKHRAQITTRQQPKERQKKVIGEIFESSSEFKFPSIHLLSKAEESLQRKRLNEMESNKNLSLLEQVLSDFGVQGKVISVCYGPVVTLYKLEPQAGTKSARVIGLADDIARSMSALSARISIIRGQNAMGIELPNKEREIVMLRDLLESLEYQNANLNLPIALGKEISGKPVIADLAKMPHLLVAGTTGSGKSVAINTMILSLIYRLSPDACKMIMIDPKMLELSIYDAIPHLITPVVTEPKKAVIALKWIVKEMENRYRMMSYLNVRNVINYNQKITEAINSGIELERVVQVGFNSTTGKPLFEKMPIKMETFSYIVVIVDEMADLMLVAGKEIECSIQRLAQMARAAGIHIIMATQRPSVDVITGVIKANFPTRISFAVTSKIDSRTILGEQGAEQLLGMGDMLYMASGGKIIRVHGPFVSDEEVQNIVDHLKMQGEPNYMEEITKEDENSSAELKGETEGEENDLYKQAVAIIQRDQKVSTSYIQRQLRIGYNRAANIVERTEKEGIISAPNYLGKREILVE
Atome Classification :
(20 SA)
-------------------.........----10........20........30.....-----...40..------......-------50.----.......60.....--------...70...------.....--80........90........100.......110..---------.....120....----...130.......140------........--------150..-----.....160------------....---.....170.......180-----.........190.......200---........210...--------....220.-------------......230..---.....240..-.....250...-----.------...260-....------.....270.......---280....---...290.......300-.......310---.........320.......330.---------......340--------.........350----.--.......360-.---......370.....----..380.......390.......400...----.----------------...410.......420-..-----......430.......440.....--..450.....---.---------.460.--------......-470.-----------......480......-----.490.-......500.----......-510........520.......530--.-.......--540.......550.....--..560.-------...-------...570.......580.......590.-..--.-.--..600.--......610.------......620------------.......---------------.630.......640--------....-.....-650.......660---------------.......--.670.......680.......690...----....700.....--------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-------------------
M
L
K
K
Y
L
K
A
A
----
I
Y
L
S
L
L
I
Y
I
Y
I
S
V
F
SYSYK
D
I
S
L
N
TVT-----
D
K
E
V
T
N
L
------
G
G
I
V
G
S
-------
Y
L
A
----
D
I
L
V
Q
F
LGL
T
S
I
T
V
--------
A
T
T
I
I
C
F
L
------IFRP
S
--
K
R
L
L
K
V
L
Y
S
V
L
I
N
L
G
I
C
A
M
L
P
Q
L
S
L
G
I
T
A
R
Y
M
HSG---------II
G
N
I
L
INNC
P
F
----
Y
I
F
I
I
A
TST
G
I
V
G
LI-------GW
K
R
T
I
Y
L
--------
L
F
L
L
Y
-----
K
K
V
A
S
L
--------------
L
A
K
V
---
L
F
F
R
L
Y
K
A
AEYPTPP
L
-------
V
V
EEKHRAQITTRQQ
P
K
E
R
Q
K
----
K
V
I
G
E
I
F
ESSSEFK--------FPS
I
H
L
L
S
-------------
K
A
E
E
S
L
Q
R
K
R
L
---
N
E
M
ESNK
N
L
S
-
L
L
E
Q
V
L
S
DFGV-----Q------
G
K
V
I
---
S
V
C
Y------GP
V
V
T
L
Y
K
LEPQAGT---K
S
A
R
V
I
G---
L
A
D
D
I
A
R
S
M
S
A
L
S
A
R
I
-
S
I
I
RGQ
N
A
-----MGIELPNKE
R
E
I
V
M
L
R
D
L
L
E
S
L
E---------YQNANLN----------
L
P
I
ALGKEISG-----K--
P
V
I
A
D
L
A
KMP-
H
---
L
L
V
AGTTGSG
K
S
V
A
----
I
N
T
M
I
L
S
L
I
Y
RLSPD
A
C
K
M
I
M
IDPK
M
L
E
----
L
----------------
S
I
Y
D
A
I
P
H
L
I
T
PVVT--EP-----
K
K
A
V
I
A
L
K
W
I
V
K
E
M
E
N
R
Y
R
M
M
S
Y
L
--
N
V
R
N
V
INY
N
Q
---
K
---------
I
T
E
A
I
--------NSGI
E
L
-
E
R
V
V
-----------
Q
VGFNSTTGK
P
L
F
E
K-----MP
I
K
M
-
E
T
F
S
Y
I
V
V
I
V
----
D
E
M
A
D
L
-
M
-
L
VAGK
E
I
E
C
S
I
Q
R
L
A
Q
M
A
R
AA---
G
-
I
H
I
I
M
AT--QRP
S
V
D
V
I
T
G
V
I
KANFP
T
--
R
I
S
F
A
V
-------TSK-------IDSRTILGE
Q
G
A
E
Q
L
L
GMG
D
M
L
Y
MASG-
G
K
--
I
-
I
--
R
V
HGPF--V
S
D
E
E
V
Q
N
I
V
------
D
H
L
KMQGE-------------
P
N
Y
M
E
E
I
---------------
T
KEDENSSAELK----------GETE-GE
E
N
D
-
L
Y
K
Q
A
V
A
I
I
QRD----------------QKV
S
T
S
Y
--
I
Q
R
Q
L
RIGY
N
R
A
A
N
I
V
E
R
T
EKEGIISA----PNYLGK
R
E
ILVE--------------------------------------------------------------------------------------------------------------------
81
Fugue
92.14
51%
-112
- C8 -
2IUT
3
FTSK_PSEAE
A:
[70-477]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
P
P
L
S
L
L
D
-------------
P
A
E
V
--
K
Q
K
S
Y
---
S
P
E
S
L
E
A
M
S
R
-
L
L
E
I
K
L
K
E
F
G
V
-----
E
------
V
S
V
D
---
S
V
H
P
------
G
P
V
I
T
R
F
E
I
Q
P
A
A
G
V
---
K
V
S
R
I
S
N
---
L
A
K
D
L
A
R
S
L
A
V
I
S
V
R
V
V
E
V
I
P
G
K
T
T
-----
V
G
I
E
I
P
N
E
D
R
Q
M
V
R
F
S
E
V
L
S
S
P
E
---------
Y
D
E
H
K
S
T
----------
V
P
L
A
L
G
H
D
I
G
G
-----
R
--
P
I
I
T
D
L
A
K
M
P
-
H
---
L
L
V
A
G
T
T
G
S
G
K
S
V
G
----
V
N
A
M
L
L
S
I
L
F
K
S
T
P
S
E
A
R
L
I
M
I
D
P
K
M
L
E
----
L
----------------
S
I
Y
E
G
I
P
H
L
L
C
P
V
V
T
--
D
M
-----
K
E
A
A
N
A
L
R
W
S
V
A
E
M
E
R
R
Y
R
L
M
A
A
M
--
G
V
R
N
L
A
G
F
N
R
---
K
---------
V
K
D
A
E
--------
E
A
G
T
P
L
-
T
D
P
L
-----------
F
R
R
E
S
P
D
D
E
P
P
Q
L
S
T
-----
L
P
--------
T
I
V
V
V
V
----
D
E
F
A
D
M
-
M
-
M
I
V
G
K
K
V
E
E
L
I
A
R
I
A
Q
K
A
R
A
A
---
G
-
I
H
L
I
L
A
T
--
Q
R
P
S
V
D
V
I
T
G
L
I
K
A
N
I
P
T
--
R
I
A
F
Q
V
-------
S
S
K
-------
I
D
S
R
T
I
L
D
Q
G
G
A
E
Q
L
L
G
H
G
D
M
L
Y
L
P
P
G
T
G
L
--
P
-
I
--
R
V
H
G
A
F
--
V
S
D
D
E
V
H
R
V
V
------
E
A
W
K
L
R
G
A
-------------
P
D
Y
I
E
D
I
---------------
L
A
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
PsiBlast_CBE
91.97
49%
-116
- C8 -
2IUU
1
FTSK_PSEAE
E:
[70-475]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
P
P
L
S
L
L
D
-------------
P
A
E
---
V
K
Q
K
S
---
Y
S
P
E
S
L
E
A
M
S
R
L
L
E
I
K
L
K
E
F
G
V
-----
E
------
V
S
V
D
---
S
V
H
P
------
G
P
V
I
T
R
F
E
I
Q
P
A
A
G
V
---
K
V
S
R
I
S
N
---
L
A
K
D
L
A
R
S
L
A
V
I
S
V
R
V
V
E
V
I
P
G
K
T
T
-----
V
G
I
E
I
P
N
E
D
R
Q
M
V
R
F
S
E
V
L
S
S
P
E
---------
Y
D
E
H
K
S
T
----------
V
P
L
A
L
G
H
D
I
G
G
-----
R
--
P
I
I
T
D
L
A
K
M
P
-
H
---
L
L
V
A
G
T
T
G
S
G
K
S
V
G
----
V
N
A
M
L
L
S
I
L
F
K
S
T
P
S
E
A
R
L
I
M
I
D
P
K
M
L
E
----
L
----------------
S
I
Y
E
G
I
P
H
L
L
C
P
V
V
T
--
D
M
-----
K
E
A
A
N
A
L
R
W
S
V
A
E
M
E
R
R
Y
R
L
M
A
A
M
--
G
V
R
N
L
A
G
F
N
R
---
K
---------
V
K
D
A
E
--------
E
A
G
T
P
L
-
T
-----------------------
D
P
L
F
R
R
ESPDD
E
P
P
Q
L
-
S
T
L
P
T
I
V
V
V
V
----
D
E
F
A
D
M
-
M
-
M
I
V
G
K
K
V
E
E
L
I
A
R
I
A
Q
K
A
R
A
A
---
G
-
I
H
L
I
L
A
T
--
Q
R
P
S
V
D
V
I
T
G
L
I
K
A
N
I
P
T
--
R
I
A
F
Q
V
-------
S
S
K
-------
I
D
S
R
T
I
L
D
Q
G
G
A
E
Q
L
L
G
H
G
D
M
L
Y
L
P
P
G
T
G
L
--
P
-
I
--
R
V
H
G
A
F
--
V
S
D
D
E
V
H
R
V
V
------
E
A
W
K
L
R
G
A
-------------
P
D
Y
I
E
D
I
---------------
L
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
91.87
49%
-116
- C8 -
2IUU
1
FTSK_PSEAE
A:
[70-475]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
P
P
L
S
L
L
D
-------------
P
A
E
---
V
K
Q
K
S
---
Y
S
P
E
S
L
E
A
M
S
R
L
L
E
I
K
L
K
E
F
G
V
-----
E
------
V
S
V
D
---
S
V
H
P
------
G
P
V
I
T
R
F
E
I
Q
P
A
A
G
V
---
K
V
S
R
I
S
N
---
L
A
K
D
L
A
R
S
L
A
V
I
S
V
R
V
V
E
V
I
P
G
K
T
T
-----
V
G
I
E
I
P
N
E
D
R
Q
M
V
R
F
S
E
V
L
S
S
P
E
---------
Y
D
E
H
K
S
T
----------
V
P
L
A
L
G
H
D
I
G
G
-----
R
--
P
I
I
T
D
L
A
K
M
P
-
H
---
L
L
V
A
G
T
T
G
S
G
K
S
V
G
----
V
N
A
M
L
L
S
I
L
F
K
S
T
P
S
E
A
R
L
I
M
I
D
P
K
M
L
E
----
L
----------------
S
I
Y
E
G
I
P
H
L
L
C
P
V
V
T
--
D
M
-----
K
E
A
A
N
A
L
R
W
S
V
A
E
M
E
R
R
Y
R
L
M
A
A
M
--
G
V
R
N
L
A
G
F
N
R
---
K
---------
V
K
D
A
E
--------
E
A
G
T
P
L
-
T
-----------------------
D
P
L
F
R
R
ESPDD
E
P
P
Q
L
-
S
T
L
P
T
I
V
V
V
V
----
D
E
F
A
D
M
-
M
-
M
I
V
G
K
K
V
E
E
L
I
A
R
I
A
Q
K
A
R
A
A
---
G
-
I
H
L
I
L
A
T
--
Q
R
P
S
V
D
V
I
T
G
L
I
K
A
N
I
P
T
--
R
I
A
F
Q
V
-------
S
S
K
-------
I
D
S
R
T
I
L
D
Q
G
G
A
E
Q
L
L
G
H
G
D
M
L
Y
L
P
P
G
T
G
L
--
P
-
I
--
R
V
H
G
A
F
--
V
S
D
D
E
V
H
R
V
V
------
E
A
W
K
L
R
G
A
-------------
P
D
Y
I
E
D
I
---------------
L
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
PsiBlast_CBE
91.73
49%
-115
- C8 -
2IUU
1
FTSK_PSEAE
D:
[70-475]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
P
P
L
S
L
L
D
-------------
P
A
E
---
V
K
Q
K
S
---
Y
S
P
E
S
L
E
A
M
S
R
L
L
E
I
K
L
K
E
F
G
V
-----
E
------
V
S
V
D
---
S
V
H
P
------
G
P
V
I
T
R
F
E
I
Q
P
A
A
G
V
---
K
V
S
R
I
S
N
---
L
A
K
D
L
A
R
S
L
A
V
I
S
V
R
V
V
E
V
I
P
G
K
T
T
-----
V
G
I
E
I
P
N
E
D
R
Q
M
V
R
F
S
E
V
L
S
S
P
E
---------
Y
D
E
H
K
S
T
----------
V
P
L
A
L
G
H
D
I
G
G
-----
R
--
P
I
I
T
D
L
A
K
M
P
-
H
---
L
L
V
A
G
T
T
G
S
G
K
S
V
G
----
V
N
A
M
L
L
S
I
L
F
K
S
T
P
S
E
A
R
L
I
M
I
D
P
K
M
L
E
----
L
----------------
S
I
Y
E
G
I
P
H
L
L
C
P
V
V
T
--
D
M
-----
K
E
A
A
N
A
L
R
W
S
V
A
E
M
E
R
R
Y
R
L
M
A
A
M
--
G
V
R
N
L
A
G
F
N
R
---
K
---------
V
K
D
A
E
--------
E
A
G
T
P
L
-
T
-----------------------
D
P
L
F
R
R
ESPDD
E
P
P
Q
L
-
S
T
L
P
T
I
V
V
V
V
----
D
E
F
A
D
M
-
M
-
M
I
V
G
K
K
V
E
E
L
I
A
R
I
A
Q
K
A
R
A
A
---
G
-
I
H
L
I
L
A
T
--
Q
R
P
S
V
D
V
I
T
G
L
I
K
A
N
I
P
T
--
R
I
A
F
Q
V
-------
S
S
K
-------
I
D
S
R
T
I
L
D
Q
G
G
A
E
Q
L
L
G
H
G
D
M
L
Y
L
P
P
G
T
G
L
--
P
-
I
--
R
V
H
G
A
F
--
V
S
D
D
E
V
H
R
V
V
------
E
A
W
K
L
R
G
A
-------------
P
D
Y
I
E
D
I
---------------
L
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
PsiBlast_CBE
91.68
49%
-116
- C8 -
2IUU
1
FTSK_PSEAE
B:
[70-475]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
P
P
L
S
L
L
D
-------------
P
A
E
---
V
K
Q
K
S
---
Y
S
P
E
S
L
E
A
M
S
R
L
L
E
I
K
L
K
E
F
G
V
-----
E
------
V
S
V
D
---
S
V
H
P
------
G
P
V
I
T
R
F
E
I
Q
P
A
A
G
V
---
K
V
S
R
I
S
N
---
L
A
K
D
L
A
R
S
L
A
V
I
S
V
R
V
V
E
V
I
P
G
K
T
T
-----
V
G
I
E
I
P
N
E
D
R
Q
M
V
R
F
S
E
V
L
S
S
P
E
---------
Y
D
E
H
K
S
T
----------
V
P
L
A
L
G
H
D
I
G
G
-----
R
--
P
I
I
T
D
L
A
K
M
P
-
H
---
L
L
V
A
G
T
T
G
S
G
K
S
V
G
----
V
N
A
M
L
L
S
I
L
F
K
S
T
P
S
E
A
R
L
I
M
I
D
P
K
M
L
E
----
L
----------------
S
I
Y
E
G
I
P
H
L
L
C
P
V
V
T
--
D
M
-----
K
E
A
A
N
A
L
R
W
S
V
A
E
M
E
R
R
Y
R
L
M
A
A
M
--
G
V
R
N
L
A
G
F
N
R
---
K
---------
V
K
D
A
E
--------
E
A
G
T
P
L
-
T
-----------------------
D
P
L
F
R
R
ESPDD
E
P
P
Q
L
-
S
T
L
P
T
I
V
V
V
V
----
D
E
F
A
D
M
-
M
-
M
I
V
G
K
K
V
E
E
L
I
A
R
I
A
Q
K
A
R
A
A
---
G
-
I
H
L
I
L
A
T
--
Q
R
P
S
V
D
V
I
T
G
L
I
K
A
N
I
P
T
--
R
I
A
F
Q
V
-------
S
S
K
-------
I
D
S
R
T
I
L
D
Q
G
G
A
E
Q
L
L
G
H
G
D
M
L
Y
L
P
P
G
T
G
L
--
P
-
I
--
R
V
H
G
A
F
--
V
S
D
D
E
V
H
R
V
V
------
E
A
W
K
L
R
G
A
-------------
P
D
Y
I
E
D
I
---------------
L
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
PsiBlast_CBE
91.35
49%
-114
- C8 -
2IUU
1
FTSK_PSEAE
F:
[70-475]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
P
P
L
S
L
L
D
-------------
P
A
E
---
V
K
Q
K
S
---
Y
S
P
E
S
L
E
A
M
S
R
L
L
E
I
K
L
K
E
F
G
V
-----
E
------
V
S
V
D
---
S
V
H
P
------
G
P
V
I
T
R
F
E
I
Q
P
A
A
G
V
---
K
V
S
R
I
S
N
---
L
A
K
D
L
A
R
S
L
A
V
I
S
V
R
V
V
E
V
I
P
G
K
T
T
-----
V
G
I
E
I
P
N
E
D
R
Q
M
V
R
F
S
E
V
L
S
S
P
E
---------
Y
D
E
H
K
S
T
----------
V
P
L
A
L
G
H
D
I
G
G
-----
R
--
P
I
I
T
D
L
A
K
M
P
-
H
---
L
L
V
A
G
T
T
G
S
G
K
S
V
G
----
V
N
A
M
L
L
S
I
L
F
K
S
T
P
S
E
A
R
L
I
M
I
D
P
K
M
L
E
----
L
----------------
S
I
Y
E
G
I
P
H
L
L
C
P
V
V
T
--
D
M
-----
K
E
A
A
N
A
L
R
W
S
V
A
E
M
E
R
R
Y
R
L
M
A
A
M
--
G
V
R
N
L
A
G
F
N
R
---
K
---------
V
K
D
A
E
--------
E
A
G
T
P
L
-
T
-----------------------
D
P
L
F
R
R
ESPDD
E
P
P
Q
L
-
S
T
L
P
T
I
V
V
V
V
----
D
E
F
A
D
M
-
M
-
M
I
V
G
K
K
V
E
E
L
I
A
R
I
A
Q
K
A
R
A
A
---
G
-
I
H
L
I
L
A
T
--
Q
R
P
S
V
D
V
I
T
G
L
I
K
A
N
I
P
T
--
R
I
A
F
Q
V
-------
S
S
K
-------
I
D
S
R
T
I
L
D
Q
G
G
A
E
Q
L
L
G
H
G
D
M
L
Y
L
P
P
G
T
G
L
--
P
-
I
--
R
V
H
G
A
F
--
V
S
D
D
E
V
H
R
V
V
------
E
A
W
K
L
R
G
A
-------------
P
D
Y
I
E
D
I
---------------
L
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
PsiBlast_CBE
91.20
49%
-115
- C8 -
2IUU
1
FTSK_PSEAE
C:
[70-475]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
P
P
L
S
L
L
D
-------------
P
A
E
---
V
K
Q
K
S
---
Y
S
P
E
S
L
E
A
M
S
R
L
L
E
I
K
L
K
E
F
G
V
-----
E
------
V
S
V
D
---
S
V
H
P
------
G
P
V
I
T
R
F
E
I
Q
P
A
A
G
V
---
K
V
S
R
I
S
N
---
L
A
K
D
L
A
R
S
L
A
V
I
S
V
R
V
V
E
V
I
P
G
K
T
T
-----
V
G
I
E
I
P
N
E
D
R
Q
M
V
R
F
S
E
V
L
S
S
P
E
---------
Y
D
E
H
K
S
T
----------
V
P
L
A
L
G
H
D
I
G
G
-----
R
--
P
I
I
T
D
L
A
K
M
P
-
H
---
L
L
V
A
G
T
T
G
S
G
K
S
V
G
----
V
N
A
M
L
L
S
I
L
F
K
S
T
P
S
E
A
R
L
I
M
I
D
P
K
M
L
E
----
L
----------------
S
I
Y
E
G
I
P
H
L
L
C
P
V
V
T
--
D
M
-----
K
E
A
A
N
A
L
R
W
S
V
A
E
M
E
R
R
Y
R
L
M
A
A
M
--
G
V
R
N
L
A
G
F
N
R
---
K
---------
V
K
D
A
E
--------
E
A
G
T
P
L
-
T
-----------------------
D
P
L
F
R
R
ESPDD
E
P
P
Q
L
-
S
T
L
P
T
I
V
V
V
V
----
D
E
F
A
D
M
-
M
-
M
I
V
G
K
K
V
E
E
L
I
A
R
I
A
Q
K
A
R
A
A
---
G
-
I
H
L
I
L
A
T
--
Q
R
P
S
V
D
V
I
T
G
L
I
K
A
N
I
P
T
--
R
I
A
F
Q
V
-------
S
S
K
-------
I
D
S
R
T
I
L
D
Q
G
G
A
E
Q
L
L
G
H
G
D
M
L
Y
L
P
P
G
T
G
L
--
P
-
I
--
R
V
H
G
A
F
--
V
S
D
D
E
V
H
R
V
V
------
E
A
W
K
L
R
G
A
-------------
P
D
Y
I
E
D
I
---------------
L
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
56
HHSearch
88.45
47%
-45
- C- -
2IUS
-
FTSK_ECOLI
A:
[840-1249]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
P
S
L
D
L
L
T
-------------
P
P
------------
T
F
A
L
-
E
Q
M
A
R
-
L
V
E
A
R
L
A
D
F
R
I
-----
K
------
A
D
V
V
---
N
Y
S
P
------
G
P
V
I
T
R
F
E
L
N
L
A
P
G
V
---
K
A
A
R
I
S
N
---
L
S
R
D
L
A
R
S
L
S
T
V
A
V
R
V
V
E
V
I
P
G
K
P
Y
-----
V
G
L
E
L
P
N
K
K
R
Q
T
V
Y
L
R
E
V
L
D
N
A
K
---------
F
R
D
N
P
S
P
----------
L
T
V
V
L
G
K
D
I
A
G
-----
E
--
P
V
V
A
D
L
A
K
M
P
-
H
---
L
L
V
A
G
T
T
G
S
G
A
S
V
G
----
V
N
A
M
I
L
S
M
L
Y
K
A
Q
P
E
D
V
R
F
I
M
I
D
P
K
M
L
E
----
L
----------------
S
V
Y
E
G
I
P
H
L
L
T
E
V
V
T
--
D
M
-----
K
D
A
A
N
A
L
R
W
C
V
N
E
M
E
R
R
Y
K
L
M
S
A
L
--
G
V
R
N
L
A
G
Y
N
E
---
K
---------
I
A
E
A
D
--------
R
M
M
R
P
I
-
P
D
P
Y
-----------
W
--------------------
H
P
V
L
-
K
K
E
P
Y
I
V
V
L
V
----
D
E
F
A
D
L
-
M
-
M
T
V
G
K
K
V
E
E
L
I
A
R
L
A
Q
K
A
R
A
A
---
G
-
I
H
L
V
L
A
T
--
Q
R
P
S
V
D
V
I
T
G
L
I
K
A
N
I
P
T
--
R
I
A
F
T
V
-------
S
S
K
-------
I
D
S
R
T
I
L
D
Q
A
G
A
E
S
L
L
G
M
G
D
M
L
Y
S
G
P
N
S
T
L
--
P
-
V
--
R
V
H
G
A
F
--
V
R
D
Q
E
V
H
A
V
V
------
Q
D
W
K
A
R
G
R
-------------
P
Q
Y
V
D
G
I
---------------
T
S
D
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
88.29
47%
-47
- C- -
2IUS
-
FTSK_ECOLI
A:
[840-1249]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
P
S
L
D
L
L
T
-------------
P
P
-------------
T
F
A
L
E
Q
M
A
R
-
L
V
E
A
R
L
A
D
F
R
I
-----
K
------
A
D
V
V
---
N
Y
S
P
------
G
P
V
I
T
R
F
E
L
N
L
A
P
G
V
---
K
A
A
R
I
S
N
---
L
S
R
D
L
A
R
S
L
S
T
V
A
V
R
V
V
E
V
I
P
G
K
P
Y
-----
V
G
L
E
L
P
N
K
K
R
Q
T
V
Y
L
R
E
V
L
D
N
A
K
---------
F
R
D
N
P
S
P
----------
L
T
V
V
L
G
K
D
I
A
G
-----
E
--
P
V
V
A
D
L
A
K
M
P
-
H
---
L
L
V
A
G
T
T
G
S
G
A
S
V
G
----
V
N
A
M
I
L
S
M
L
Y
K
A
Q
P
E
D
V
R
F
I
M
I
D
P
K
M
L
E
----
L
----------------
S
V
Y
E
G
I
P
H
L
L
T
E
V
V
T
--
D
M
-----
K
D
A
A
N
A
L
R
W
C
V
N
E
M
E
R
R
Y
K
L
M
S
A
L
--
G
V
R
N
L
A
G
Y
N
E
---
K
---------
I
A
E
A
D
--------
R
M
M
R
P
I
P
D
P
Y
W
--------------------
H
P
V
L
K
K
-----
E
P
--------
Y
I
V
V
L
V
----
D
E
F
A
D
L
-
M
-
M
T
V
G
K
K
V
E
E
L
I
A
R
L
A
Q
K
A
R
A
A
---
G
-
I
H
L
V
L
A
T
--
Q
R
P
S
V
D
V
I
T
G
L
I
K
A
N
I
P
T
--
R
I
A
F
T
V
-------
S
S
K
-------
I
D
S
R
T
I
L
D
Q
A
G
A
E
S
L
L
G
M
G
D
M
L
Y
S
G
P
N
-
S
T
--
L
P
V
--
R
V
H
G
A
F
--
V
R
D
Q
E
V
H
A
V
V
------
Q
D
W
K
A
R
G
R
-------------
P
Q
Y
V
D
G
I
---------------
T
S
D
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
55
HHSearch
87.43
48%
-40
- C- -
2IUT
3
FTSK_PSEAE
A:
[70-478]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
P
P
L
S
L
L
D
-------------
P
A
E
V
K
-
Q
K
S
Y
S
---
P
E
S
L
-
E
A
M
S
R
-
L
L
E
I
K
L
K
E
F
G
V
-----
E
------
V
S
V
D
---
S
V
H
P
------
G
P
V
I
T
R
F
E
I
Q
P
A
A
G
V
---
K
V
S
R
I
S
N
---
L
A
K
D
L
A
R
S
L
A
V
I
S
V
R
V
V
E
V
I
P
G
K
T
T
-----
V
G
I
E
I
P
N
E
D
R
Q
M
V
R
F
S
E
V
L
S
S
P
E
---------
Y
D
E
H
K
S
T
----------
V
P
L
A
L
G
H
D
I
G
G
-----
R
--
P
I
I
T
D
L
A
K
M
P
-
H
---
L
L
V
A
G
T
T
G
S
G
K
S
V
G
----
V
N
A
M
L
L
S
I
L
F
K
S
T
P
S
E
A
R
L
I
M
I
D
P
K
M
L
E
----
L
----------------
S
I
Y
E
G
I
P
H
L
L
C
P
V
V
T
--
D
M
-----
K
E
A
A
N
A
L
R
W
S
V
A
E
M
E
R
R
Y
R
L
M
A
A
M
--
G
V
R
N
L
A
G
F
N
R
---
K
---------
V
K
D
A
E
--------
E
A
G
T
P
L
-
T
D
P
L
-----------
F
R
R
E
S
P
-------
D
D
-----
E
P
P
Q
L
-
S
T
L
P
T
I
V
V
V
V
----
D
E
F
A
D
M
-
M
-
M
I
V
G
K
K
V
E
E
L
I
A
R
I
A
Q
K
A
R
A
A
---
G
-
I
H
L
I
L
A
T
--
Q
R
P
S
V
D
V
I
T
G
L
I
K
A
N
I
P
T
--
R
I
A
F
Q
V
-------
S
S
K
-------
I
D
S
R
T
I
L
D
Q
G
G
A
E
Q
L
L
G
H
G
D
M
L
Y
L
P
P
G
T
G
L
--
P
-
I
--
R
V
H
G
A
F
--
V
S
D
D
E
V
H
R
V
V
------
E
A
W
K
L
R
G
A
-------------
P
D
Y
I
E
D
I
---------------
L
A
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
87.24
46%
-47
- C- -
2IUT
3
FTSK_PSEAE
B:
[70-478]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
P
P
L
S
L
L
D
-------------
P
A
E
---
V
K
Q
K
S
---
Y
S
P
E
S
L
E
A
M
S
R
L
L
E
I
K
L
K
E
F
G
V
-----
E
------
V
S
V
D
---
S
V
H
P
------
G
P
V
I
T
R
F
E
I
Q
P
A
A
G
V
---
K
V
S
R
I
S
N
---
L
A
K
D
L
A
R
S
L
A
V
I
S
V
R
V
V
E
V
I
P
G
K
T
T
-----
V
G
I
E
I
P
N
E
D
R
Q
M
V
R
F
S
E
V
L
S
S
P
E
---------
Y
D
E
H
K
S
T
----------
V
P
L
A
L
G
H
D
I
G
G
-----
R
--
P
I
I
T
D
L
A
K
M
P
-
H
---
L
L
V
A
G
T
T
G
S
G
K
S
V
G
----
V
N
A
M
L
L
S
I
L
F
K
S
T
P
S
E
A
R
L
I
M
I
D
P
K
M
L
E
----
L
----------------
S
I
Y
E
G
I
P
H
L
L
C
P
V
V
T
--
D
M
-----
K
E
A
A
N
A
L
R
W
S
V
A
E
M
E
R
R
Y
R
L
M
A
A
M
--
G
V
R
N
L
A
G
F
N
R
---
K
---------
V
K
D
A
E
--------
E
A
G
T
P
L
-
T
-----------------------
D
P
L
F
R
R
ESPDD
E
P
P
Q
L
-
S
T
L
P
T
I
V
V
V
V
----
D
E
F
A
D
M
-
M
-
M
I
V
G
K
K
V
E
E
L
I
A
R
I
A
Q
K
A
R
A
A
---
G
-
I
H
L
I
L
A
T
--
Q
R
P
S
V
D
V
I
T
G
L
I
K
A
N
I
P
T
--
R
I
A
F
Q
V
-------
S
S
K
-------
I
D
S
R
T
I
L
D
Q
G
G
A
E
Q
L
L
G
H
G
D
M
L
Y
L
P
P
G
T
G
L
--
P
-
I
--
R
V
H
G
A
F
--
V
S
D
D
E
V
H
R
V
V
------
E
A
W
K
L
R
G
A
-------------
P
D
Y
I
E
D
I
L--------------
A
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
87.24
46%
-48
- C- -
2IUT
3
FTSK_PSEAE
A:
[70-478]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
P
P
L
S
L
L
D
-------------
P
A
E
---
V
K
Q
K
S
---
Y
S
P
E
S
L
E
A
M
S
R
L
L
E
I
K
L
K
E
F
G
V
-----
E
------
V
S
V
D
---
S
V
H
P
------
G
P
V
I
T
R
F
E
I
Q
P
A
A
G
V
---
K
V
S
R
I
S
N
---
L
A
K
D
L
A
R
S
L
A
V
I
S
V
R
V
V
E
V
I
P
G
K
T
T
-----
V
G
I
E
I
P
N
E
D
R
Q
M
V
R
F
S
E
V
L
S
S
P
E
---------
Y
D
E
H
K
S
T
----------
V
P
L
A
L
G
H
D
I
G
G
-----
R
--
P
I
I
T
D
L
A
K
M
P
-
H
---
L
L
V
A
G
T
T
G
S
G
K
S
V
G
----
V
N
A
M
L
L
S
I
L
F
K
S
T
P
S
E
A
R
L
I
M
I
D
P
K
M
L
E
----
L
----------------
S
I
Y
E
G
I
P
H
L
L
C
P
V
V
T
--
D
M
-----
K
E
A
A
N
A
L
R
W
S
V
A
E
M
E
R
R
Y
R
L
M
A
A
M
--
G
V
R
N
L
A
G
F
N
R
---
K
---------
V
K
D
A
E
--------
E
A
G
T
P
L
-
T
-----------------------
D
P
L
F
R
R
ESPDD
E
P
P
Q
L
-
S
T
L
P
T
I
V
V
V
V
----
D
E
F
A
D
M
-
M
-
M
I
V
G
K
K
V
E
E
L
I
A
R
I
A
Q
K
A
R
A
A
---
G
-
I
H
L
I
L
A
T
--
Q
R
P
S
V
D
V
I
T
G
L
I
K
A
N
I
P
T
--
R
I
A
F
Q
V
-------
S
S
K
-------
I
D
S
R
T
I
L
D
Q
G
G
A
E
Q
L
L
G
H
G
D
M
L
Y
L
P
P
G
T
G
L
--
P
-
I
--
R
V
H
G
A
F
--
V
S
D
D
E
V
H
R
V
V
------
E
A
W
K
L
R
G
A
-------------
P
D
Y
I
E
D
I
L--------------
A
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
84
Fugue
63.84
20%
-96
* C9 *
4NH0
5
?
A:
[246-1147]
-------------------
S
A
N
M
T
L
T
S
L
----
L
H
I
D
N
P
Y
N
L
D
P
A
V
L
W
R
P
R
P
Q
R
N
R
L
R
V
P
IGLDA
D
G
R
P
L
E
L
D
IKESA
Q
G
G
M
G
P
-------
H
G
L
----
C
I
G
A
T
G
S
G
K
S
E
L
L
R
--------
T
L
V
L
A
L
A
M
------
T
H
S
P
-------
E
V
L
N
F
V
L
V
D
F
K
G
G
A
T
F
----
L
G
M
E
G
L
R
H
V
S
A
---------
I
I
T
N
L
E
------------------
E
E
L
P
L
V
D
-------
R
M
Y
D
A
L
H
G
--------
E
M
V
R
R
-----
Q
E
H
L
R
H
--------------
S
G
N
Y
---
A
S
L
R
D
Y
E
K
A
R
M
E
G
A
P
L
P
P
M
P
T
L
F
I
V
L
D
E
F
S
E
L
L
S
----
A
K
P
D
F
A
----
E
L
F
V
M
I
G
R
L
G
R
S
L
-----------
G
V
H
L
L
L
-------------
A
S
Q
-
R
L
E
E
G
K
L
---
R
G
L
--
D
T
H
L
S
-
Y
R
I
G
L
R
T
F
S
A
M
-----
E
------
S
R
V
V
LGV
P
D
A
Y
ELPPSP
G
N
G
Y
L
K
F
A
T
E
P
L
V
R
F
---
K
A
A
Y
V
S
G
---
P
V
D
E
E
S
E
S
L
F
D
V
V
V
R
Q
-
L
A
G
H
G
P
E
P
-----
H
Q
I
W
L
P
P
L
D
V
P
P
T
-
L
D
E
L
L
P
P
L
S
---------
P
S
A
A
H
G
Y
TADGWEWRGR
L
H
A
V
V
G
L
V
D
R
P
FDQ
R
R
D
--
P
Y
W
L
D
L
S
G
G
A
G
H
---
V
G
V
A
G
G
P
Q
T
G
K
S
T
M
----
L
R
T
L
I
T
S
L
A
L
L
H
T
P
Q
E
V
Q
F
Y
C
L
D
F
G
G
G
T
----
L
----------------
A
G
L
A
E
L
P
H
-
V
G
S
V
A
T
--
R
L
D
A
D
R
I
R
R
T
V
A
E
V
S
A
L
L
E
Q
R
E
Q
E
F
T
E
-------------------------------
R
G
I
--------
D
S
M
A
T
Y
-
R
R
L
R
-----------
A
T
G
E
Y
A
G
D
G
-------------------
F
G
D
V
F
L
V
V
----
D
N
W
L
T
L
-
R
-
Q
D
Y
-
E
A
L
E
D
S
I
T
Q
L
A
A
R
G
L
G
Y
---
G
-
I
H
V
V
L
S
S
--
N
K
--
W
S
E
F
R
T
S
I
R
D
L
L
G
T
--
K
L
E
L
R
L
GDPYESE
V
D
R
-------
K
K
A
A
N
V
P
E
N
R
P
G
R
G
L
T
R
D
G
Y
H
F
L
T
A
-------
L
-
P
--
R
I
D
G
D
T
--
S
A
E
T
L
T
E
G
I
A
------
T
T
V
K
T
I
R
E
A
W
HGPTAPPVRML
P
N
V
L
P
A
A
QLPSAAESGTRIPIG
I
D
E
D
S
L
S
P
V
Y
L
D
FNTDP
H
F
L
V
F
G
D
T
E
C
G
K
S
N
L
-
L
R
L
I
T
A
G
I
I
E
R
Y
TPQQ
A
R
L
I
F
IDYSRSL
L
D
V
A
T
T
E
--
H
Q
I
G
Y
A
A
S
S
T
A
A
S
S
L
V
R
D
I
K
G
A
M
E
A
R
L
----
P
P
P
D
L
T
P
E
Q
L
R
S
RSW
W
T
G
A
E
L
F
L
V
V
D
DYEMVATSDNPLRPLAELLPQARDIG
L
H
L
I
I
A
R
S
MGGAGRALYE
P
I
I
Q
R
I
K
E
M
A
S
P
G
L
V
M
S
GNKDEGILLGN
V
K
P
H
KLPQG
R
G
Y
F
V
E
RRS
G
T
R
L
I
Q
T
A
Y
R
E
S
87
Fugue
54.02
18%
-84
- C3 -
4ZUZ
-
?
A:
[7-863]
-------------------
D
V
I
K
F
K
E
P
E
RCDY
L
Y
V
D
E
N
N
K
V
H
I
L
L
P
I
V
G
G
D
E
I
G
L
D
N
T
C
-----
Q
T
A
V
E
L
I
------
T
F
F
Y
G
S
AHSGVTK
Y
S
A
----
E
H
Q
L
S
E
Y
K
R
Q
L
E
E
D
--------
I
K
A
I
N
S
Q
K
------
K
I
S
P
H
AY
D
D
L
L
K
E
K
I
E
R
L
Q
Q
I
E
K
Y
I
E
L
I
Q
V
---
L
K
K
Q
Y
D
E
Q
N
---------
D
I
R
Q
L
R
T
G
G
I
P
Q
LP
S
G
V
K
E
I
I
K
S
S
E
N
A
F
A
V
R
L
S
P
YDND
K
F
T
R
F
D
D
P
--------
L
F
N
V
K
-----
R
N
I
S
K
Y
DTPSRQ
A
P
I
P
I
YEG
L
G
Y
R
---
L
R
S
T
L
F
P
E
D
K
T
P
T
P
I
N
-------
K
K
S
L
R
D
K
V
K
S
T
V
L
S
H
Y
K
D
E
D
R
IDGE
K
K
D
E
K
L
N
E
L
I
T
N
L
Q
--------
N
E
L
V
K
E
L
V
-------------
K
S
D
P
Q
Y
S
K
L
S
L
---
S
K
D
P
R
G
K
E
I
N
-
Y
D
Y
L
V
N
S
L
M
L
V
DNDSE
I
------
G
D
W
I
---
D
T
I
L
------
D
A
T
V
D
S
T
V
W
A
V
Q
A
S
S
PFY
Q
G
A
K
E
I
S
S
D
R
D
A
D
K
I
S
I
R
V
Q
Y
L
L
A
E
A
-
N
I
Y
C
K
T
N
K
LSDAN
F
G
E
F
F
D
K
E
P
H
A
T
E
I
A
K
R
V
K
E
G
F
T
Q
GAD
I
E
P
I
I
Y
D
Y
I
N
S
N
HAELGLKSP-
L
T
G
K
Q
Q
Q
E
I
T
D
-----
K
F
T
K
H
Y
N
T
I
K
E
S
P
-
H
FD
E
F
F
V
A
D
P
D
K
K
G
N
I
F
S
H
QGR
I
S
C
H
F
L
D
F
F
T
R
Q
T
K
G
K
H
P
L
G
D
L
A
S
H
Q
E
A
----
L
Q
E
GTSNRLHHKN
E
V
V
A
Q
G
Y
E
K
L
D
Q
F
K
K
E
V
V
K
L
L
A
E
-----
N
K
P
K
E
L
L
D
Y
L
V
A
T
S
P
T
G
V
P
N
Y
S
M
L
S
K
E
T
Q
N
Y
I
A
Y
N
R
N
W
P
A
---------
I
Q
K
E
L
E
K
ATSIP
E
S
Q
K
Q
D
L
-
S
R
L
L
SRDNLQ
H
D
N
L
S
A
I
T
W
S
K
Y
S
S
K
P
L
L
D
V
-----
E
L
N
K
I
A
E
G
L
E
L
T
A
K
I
Y
----
N
E
K
R
G
R
-
E
W
W
F
A
G
S
R
N
E
A
R
K
T
Q
C
E
E
L
Q
R
V
S
---
K
E
I
N
T
L
L
Q
S
--
E
S
L
T
K
S
Q
V
L
E
K
V
L
N
S
I
E
T
L
D
K
I
D
R
D
I
-------
S
A
E
SNWFQS
T
L
Q
K
E
V
R
L
F
R
D
Q
L
K
D
I
C
Q
L
D
K
Y
Y
F
K
S
T
K
L
D
E
--
I
-
I
S
L
E
M
E
E
Q
F
Q
K
I
Q
D
P
A
V
Q
Q
I
V
------
R
D
L
P
S
H
C
H
N------------
D
E
A
I
E
F
F
---------------
K
T
L
N
P
E
E
A
A
K
V
A
----------
S
Y
L
S
-
L
E
Y
R
E
-
I
N
K
S
T
D
K
K
T
L
L
E
----------------
Q
D
I
P
R
L
F
K
E
V
N
T
Q
L
L
S
K
L
K
E
E
K
A
I
D
E
Q
V
H
E
K
L
S
Q
L
A
DKIA
P
E
H
F
T
R
N
N
I
I
K
W
S
T------------------------------------------------------------------------------------------------------------------
90
Fugue
50.42
13%
-76
- C1 -
3AHC
15
?
A:
[25-826]
VIGTPWQKLDRPVS
E
E
A
I
E
G
M
D
K
Y
W
R
V
T
----
N
Y
M
S
I
G
Q
-
I
Y
L
R
S
N
P
L
M
K
E
P
F
T
R
D
D
V
K
-----
H
R
L
V
G
H
W
------
G
T
T
P
G
L
-------
N
F
L
L
A
H
I
N
R
L
I
A
D
H
Q
Q
N
T
V
F
I
MGPGHG
G
P
A
G
T
S
Q
S
Y
V
D
G
T
Y
T
E
Y
Y
P
N
I
--
T
K
D
E
A
G
L
Q
K
F
F
R
Q
F
S
Y
P
G
G
I
P
S
H
F
A
P
E
T
P
G
S
I
H
E
G
GELGY
A
L
S
H
A
Y
G
A
V
M
N
N
P
S
L
F
----
V
P
C
I
I
G
D
G
E
A
E
T
G
P
L
A
T
-----
G
W
Q
S
N
K
L
V
NPRT
D
G
I
V
L
P
I
L
H
LNGYK
I
A
N
P
T
I
--------------
L
A
R
I
S
D
E
E
L
H
D
F
F
R
G
M
G
Y
H
P
Y
E
F
-------
V
A
G
F
D
N
E
D
H
M
S
I
H
R
R
F
A
E
L
F
E
----
T
I
F
D
E
I
C
D
I
K
A
A
A
Q
T
DDMTRPF
Y
P
M
L
I
F
R
T
P
KGWTCPKFIDGK
K
T
E
G
S
W
R
A
H
Q
V
PLA
S
A
R
D
T
E
E
H
F
E
-
V
L
K
G
W
M
E
S
Y
K
P
-----
E
E
L
F
NAD
G
S
I
K
---
D
D
V
T
------
A
F
---
M
P
K
G
E
L
R
I
G
A
---
N
P
N
A
N
G
G
---
V
I
R
E
D
L
K
L
P
E
L
D
Q
Y
E
V
-
T
G
V
K
E
Y
G
H
-----
G
W
G
Q
V
E
A
P
R
A
L
G
A
Y
C
R
D
I
I
K
N
---------------
N
P
D
----------
S
F
R
I
F
G
P
D
E
T
A
-----
S
--
N
R
L
N
A
T
Y
E
V
T
-
D
---
K
Q
W
D
N
G
Y
L
S
G
L
V
D
E
----
H
M
A
V
T
G
Q
V
T
E
Q
L
S
E
H
Q
C
E
G
F
L
E
A
Y
L
L
T
G
R
H
G
I
W
----------------
S
S
Y
E
S
F
V
H
V
I
D
S
M
L
N
--
Q
H
-----
A
K
W
L
E
A
T
V
R
E
I
P
-
W
R
K
P
I
S
S
V
N
L
L
--
V
S
S
H
V
W
R
Q
D
H
---
N
GFSHQDPG
V
T
S
L
L
I
--------
N
K
T
F
N
N
-
D
H
V
T
-----------
N
I
Y
F
-
A
T
D
A
N
M
L
L
A
I
-----
S
E
K
C
F
-
K
S
T
N
K
I
N
A
I
F
A
G
K
Q
P
A
P
T
W
V
T
L
-
D
E
A
R
A
E
L
E
A
G
A
A
E
W
K
W
A
S
N
A
E
NND
E
-
V
Q
V
V
L
A
S
A
G
D
V
P
T
Q
E
L
M
A
A
S
D
A
L
N
K
M
---
G
I
K
F
K
V
-------
V
N
V
-------
V
D
L
L
K
L
Q
S
R
E
N
N
D
E
A
L
T
D
E
E
F
T
E
L
F
T
A
-
D
K
P
V
L
-
F
--
A
Y
H
S
Y
-----
A
Q
D
V
R
G
L
I
Y
DRPNH
D
N
F
H
V
V
G
----------------
Y
K
E
Q
G
---------------
S
T
T
T
P
F
D
M
V
R
V
N
----------
D
-------
M
D
-
R
Y
A
L
Q
A
A
A
L
K
L
I
----------------
D
A
D
K
Y
A
D
--
K
I
D
E
L
N
A
F
R
K
K
A
F
Q
F
A
V
D
N
G
Y
D
I
P
E
F
T
----
D
W
V
Y
P
D
V
-------------------------------------------------------------------------------------------------------------------------
29
PsiBlast_CBE
41.95
41%
31
- C10 -
2VE9
2
FTSK_PSEAE
D:
[9-67]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
P
L
Y
D
E
A
V
R
F
V
T
E
S
----------------
R
R
A
S
I
S
A
--
V
Q
R
K
L
K
I
G
Y
N
R
A
A
R
M
I
E
A
M
E
M
A
G
V
V
T
P
----
M
N
T
N
G
S
R
E
V
I
A
P
--------------------------------------------------------------------------------------------------------------------
31
PsiBlast_CBE
41.83
41%
39
- C10 -
2VE9
2
FTSK_PSEAE
B:
[9-67]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
P
L
Y
D
E
A
V
R
F
V
T
E
S
----------------
R
R
A
S
I
S
A
--
V
Q
R
K
L
K
I
G
Y
N
R
A
A
R
M
I
E
A
M
E
M
A
G
V
V
T
P
----
M
N
T
N
G
S
R
E
V
I
A
P
--------------------------------------------------------------------------------------------------------------------
28
PsiBlast_CBE
41.81
41%
40
- C10 -
2VE9
2
FTSK_PSEAE
E:
[9-67]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
P
L
Y
D
E
A
V
R
F
V
T
E
S
----------------
R
R
A
S
I
S
A
--
V
Q
R
K
L
K
I
G
Y
N
R
A
A
R
M
I
E
A
M
E
M
A
G
V
V
T
P
----
M
N
T
N
G
S
R
E
V
I
A
P
--------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
40.79
48%
34
- C10 -
2J5P
-
FTSK_ECOLI
A:
[1264-1323]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
L
D
P
-
L
F
D
Q
A
V
Q
F
V
T
E
K
----------------
R
K
A
S
I
S
G
--
V
Q
R
Q
F
R
I
G
Y
N
R
A
A
R
I
I
E
Q
M
E
A
Q
G
I
V
S
E
----
Q
G
H
N
G
N
R
E
V
L
----------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
40.75
41%
35
- C10 -
2J5O
-
FTSK_PSEAE
A:
[741-805]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
E
-
G
S
E
D
D
P
L
Y
D
E
A
V
R
F
V
T
E
S
----------------
R
R
A
S
I
S
A
--
V
Q
R
K
L
K
I
G
Y
N
R
A
A
R
M
I
E
A
M
E
M
A
G
V
V
T
P
----
M
N
T
N
G
S
R
E
V
I
A
---------------------------------------------------------------------------------------------------------------------