@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Wbm0652: (2015-12-03 )
MAYEHKWYIIKVNYGHERNILELVSNAVYFKEVFIPYQTVCNSKSDIKEVCEVYVCMYLCDESRDILSKTLGFHSGDSSNFKIVLDEEVNLKRKEFNKYKWYILRVASNYEEKVCQHVLENSMRLGVNDYFKEVFIPYEELSEVELRSKKAAMRRKCFPGYVFLYVDLCDEVLNFVNNIPKSLKVYGFLKNGSVPKVISDDEIYSMCNALYNAQETKKLSHGYEKGEKVKINDGLFQNFTGKVDMINDEKKIINIEVSILGKPTIIELDLAQVEKIED
Atome Classification :
(20 SA)
--.........10........20........30........40........50........60........70........80........90........100..------.....110.......120--...------......130....-----...140.-----------...-...150----------------------------------------------------------------........160.......170---.........180.......190.-......200......--.210....-----..---.220.......230.......240.......250....-...260-----.........270......-
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
--MAY
E
H
K
W
Y
I
I
K
V
NYGHE
R
N
I
L
E
L
V
SN
A
V
Y
F
K
E
V
F
I
P
Y
Q
T
VCNS
K
S
D
I
K
E
V
C
E
V
Y
V
C
M
Y
LCDE
S
R
D
I
L
S
K
T
LGFHSGDSS
N
F
K
I
V
LDEEVN
L
K
R
K
EFNK
Y
K
W
Y
I
L
------
R
VASN
Y
E
E
K
V
C
Q
H
V
L
E
----
N
S
M
------RLG
V
N
D
Y
F
K
E
V
FI-----
P
Y
E
E
L
S
E
-----------
V
E
L
-
R
S
K
K
A
-----------------------------------------------------------------
A
M
R
RKCFP
G
Y
V
F
L
Y
V
D
L
C
D
-----
E
V
L
N
F
V
N
NIPKS
L
K
V
Y
G
F
L
KNGS-V
P
K
VIS
D
D
E
I
Y
S
M
C
N
--
A
L
Y
N
A
Q
E
T
-----
K
K
---
L
SHGYEKG
E
K
V
KINDG
L
F
Q
NFTGKVDMINDE
K
K
I
I
N
I
E
-
V
S
I
L-------GK
P
T
I
I
E
L
D
L
A
Q
V
E
KIED-
2
PsiBlast_PDB
90.19
32%
-123
- C3 -
2LQ8
-
NUSG_THEMA
A:
[4-177]
---------------------------------------------------------------------------------------------------
K
K
K
W
Y
I
V
------
L
T
M
S
G
Y
E
E
K
V
K
E
N
I
E
K
----
K
V
E
------
A
T
G
I
K
N
L
V
G
R
I
V
I
-----
P
-------------------
I
-
R
G
G
Q
R
-----------------------------------------------------------------
R
K
S
E
K
L
F
P
G
Y
V
F
V
E
M
I
M
N
D
-----
E
A
Y
N
F
V
R
S
V
P
Y
---
V
M
G
F
V
S
S
G
G
-
Q
P
V
P
V
K
D
R
E
M
R
P
I
L
R
L
A
G
L
E
E
Y
E
E
K
-----
K
K
P
V
K
V
E
L
G
F
K
V
G
D
M
V
K
I
I
S
G
P
F
E
D
F
A
G
V
I
K
E
I
D
P
E
R
Q
E
L
K
V
N
-
V
T
I
F
-------
G
R
E
T
P
V
V
L
H
V
S
E
V
E
K
I
E
--
24
HHSearch
79.94
31%
-103
- C3 -
2LQ8
-
NUSG_THEMA
A:
[2-177]
-------------------------------------------------------------------------------------------------
A
M
K
K
K
W
Y
I
V
------
L
T
M
S
G
Y
E
E
K
V
K
E
N
I
E
K
K
V
E
A
T
G
I
---------------
K
N
L
V
-----
G
R
I
V
I
P
I
-------------
R
-
G
G
Q
R
------------------------------------------------------------------
R
K
S
E
K
L
F
P
G
Y
V
F
V
E
M
I
M
N
D
-----
E
A
Y
N
F
V
R
S
V
P
Y
V
M
---
G
F
V
S
S
G
G
-
Q
P
V
P
V
K
D
R
E
M
R
P
I
L
R
--
L
A
G
L
E
E
Y
E
EKKKP
V
K
---
V
E
L
G
F
K
V
G
D
M
V
K
I
I
S
G
P
F
E
D
F
A
G
V
I
K
E
I
D
P
E
R
Q
E
L
K
V
N
-
V
T
I
F
-------
G
R
E
T
P
V
V
L
H
V
S
E
V
E
K
I
E
--
25
HHSearch
78.94
29%
-125
- C3 -
1M1H
-
NUSG_AQUAE
A:
[5-186]
----------------------------------------------------------------------------------------------
Q
V
Q
E
L
E
K
K
W
Y
A
L
------
Q
V
E
P
G
K
E
N
E
A
K
E
N
L
L
K
----
V
L
E
------
L
E
G
L
K
D
L
V
D
E
V
I
V
-----
P
A
E
E
K
V
V
-----------
I
R
A
-
Q
G
K
E
K
Y
R
L
S
LKGN
A
R
D
I
S
V
L
G
KK
G
V
T
T
F
R
I
E
NG
E
V
K
V
VESVEGDTCVNAPPISKPG
Q
K
I
T
CKENK
T
E
A
K
I
V
L
D
N
K
I
F
P
G
Y
I
L
I
K
A
H
M
N
D
-----
K
L
L
M
A
I
E
K
T
P
H
V
F
---
R
P
V
M
V
G
G
-
K
P
V
P
L
K
E
E
E
V
Q
N
I
L
N
--
Q
I
K
R
-----------------------------------------------------------------------------------
43
Fugue
77.37
25%
-80
- C3 -
1NPP
-
NUSG_AQUAE
A:
[5-248]
Q
V
Q
E
L
E
K
K
W
Y
A
L
Q
V
E
P
G
K
E
N
E
A
K
E
N
L
L
K
V
L
E
L
E
G
L
-------------
K
D
L
V
D
E
V
I
V
----------
P
A
E
E
K
V
V
I
R
A
Q
G
K
E
K
Y
R
L
S
L
K
G
--
N
A
R
D
I
S
V
L
G
K
K
G
V
T
T
------
F
R
I
E
N
G
E
V
K
V
V
E
---------
S
V
------
E
G
D
T
C
V
N
A
P
P
I
S
K
-----
P
G
Q
K
I
T
C
-----------
K
E
N
K
T
E
A
K
I
-----------------------------------------------------------------
V
L
D
N
K
I
F
P
G
Y
I
L
I
K
A
H
M
N
D
-----
K
L
L
M
A
I
E
K
T
P
H
---
V
F
R
P
V
M
V
G
G
-
K
P
V
P
L
K
E
E
E
V
Q
N
I
L
N
--
Q
I
K
R
G
V
K
P
-----
S
K
---
V
E
--
F
E
K
G
D
Q
V
R
V
I
E
G
P
F
M
N
F
T
G
T
V
E
E
V
H
P
E
K
R
K
L
T
V
M
-
I
S
I
F
-------
G
R
M
T
P
V
E
L
D
F
D
Q
V
E
K
I
---
44
Fugue
71.27
21%
-118
- C3 -
3P8B
9
SPT5_PYRFU
B:
[2-148]
---------------------------------------------------------------------------------------------------
A
G
K
I
F
A
V
------
R
V
T
H
G
Q
E
E
T
T
A
K
L
I
Y
S
----
K
V
R
------
T
Y
N
L
P
--
I
Y
A
I
L
A
-----
P
S
R
-----------------------------------------------------------------------------------------------
V
K
G
Y
I
F
V
E
A
P
N
K
G
-----
V
V
D
E
A
I
R
G
I
R
H
---
A
R
G
V
L
------
P
G
E
V
P
F
K
E
I
E
H
F
---------
L
E
E
-----
K
P
---
A
V
S
G
L
E
P
G
D
L
V
E
V
I
A
G
P
F
K
G
Q
K
A
K
V
V
K
I
D
E
S
K
D
E
V
V
V
Q
-
F
I
D
A
-------
I
V
P
I
P
V
T
I
K
G
D
Y
V
R
L
I
S
K
L
7
PsiBlast_PDB
68.73
29%
-122
- C3 -
2K06
-
NUSG_ECOLI
A:
[3-123]
------------------------------------------------------------------------------------------------
E
A
P
K
K
R
W
Y
V
V
------
Q
A
F
S
G
F
E
G
R
V
A
T
S
L
R
E
----
H
I
K
------
L
H
N
M
E
D
L
F
G
E
V
M
V
-----
P
T
E
E
V
V
E
-----------
I
R
G
-
G
Q
R
R
K
-----------------------------------------------------------------
S
-
E
R
K
F
F
P
G
Y
V
L
V
Q
M
V
M
N
D
-----
A
S
W
H
L
V
R
S
V
P
---
R
V
M
G
F
I
G
G
T
S
D
R
P
A
P
I
S
D
K
E
V
D
A
I
M
N
--
R
L
Q
Q
V
G
D
K
-----
P
R
------------------------------------------------------------------------
3
PsiBlast_PDB
67.73
35%
-115
- C3 -
2XHC
-
NUSG_THEMA
A:
[228-352]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
R
K
L
F
P
G
Y
V
F
V
E
M
I
M
N
D
-----
E
A
Y
N
F
V
R
S
V
P
Y
---
V
M
G
F
V
S
S
G
G
-
Q
P
V
P
V
K
D
R
E
M
R
P
I
L
R
L
A
G
L
E
E
Y
--------------
E
L
G
F
K
V
G
D
M
V
K
I
I
S
G
P
F
E
D
F
A
G
V
I
K
E
I
D
P
E
R
Q
E
L
K
V
N
-
V
T
I
F
-------
G
R
E
T
P
V
V
L
H
V
S
E
V
E
K
I
---
27
HHSearch
64.46
19%
-97
- C3 -
3P8B
9
SPT5_PYRFU
B:
[2-147]
---------------------------------------------------------------------------------------------------
A
G
K
I
F
A
V
------
R
V
T
H
G
Q
E
E
T
T
A
K
L
I
Y
S
----
K
V
R
---------------
T
Y
N
L
-----
P
I
Y
A
I
L
A
----------------------------------------------------------------------------------------
P
S
R
V
K
G
Y
I
F
V
E
A
P
N
K
G
-----
V
V
D
E
A
I
R
G
I
R
H
A
R
---
G
V
------
L
P
G
E
V
P
F
K
E
I
E
H
F
L
E
--
E
K
------------
P
---
A
V
S
G
L
E
P
G
D
L
V
E
V
I
A
G
P
F
K
G
Q
K
A
K
V
V
K
I
D
E
S
K
D
E
V
V
V
Q
F
I
D
A
I
-------
V
-
P
I
P
V
T
I
K
G
D
Y
V
R
L
I
S
K
-
28
HHSearch
63.71
31%
-115
- C3 -
1NZ8
-
NUSG_THET8
A:
[2-118]
---------------------------------------------------------------------------------------------------
S
I
E
W
Y
A
V
------
H
T
L
V
G
Q
E
E
K
A
K
A
N
L
E
K
----
R
I
K
------
A
F
G
L
Q
D
K
I
F
Q
V
L
I
-----
P
T
E
E
V
V
E
-----------
L
R
E
-
G
G
K
K
E
-----------------------------------------------------------------
V
V
R
K
K
L
F
P
G
Y
L
F
I
Q
M
D
L
G
D
EEEPN
E
A
W
E
V
V
R
G
T
P
G
I
T
---
G
F
V
G
A
G
M
-
R
P
V
P
L
S
P
D
E
V
R
H
I
L
E
--
V
S
G
L
L
G
---------------------------------------------------------------------------------
5
PsiBlast_PDB
62.97
31%
-99
- C3 -
1NPP
-
NUSG_AQUAE
A:
[127-248]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
I
-----------------------------------------------------------------
V
L
D
N
K
I
F
P
G
Y
I
L
I
K
A
H
M
N
D
-----
K
L
L
M
A
I
E
K
T
P
H
---
V
F
R
P
V
M
V
G
G
-
K
P
V
P
L
K
E
E
E
V
Q
N
I
L
N
--
Q
I
K
R
G
V
K
P
-----
S
K
---
V
E
--
F
E
K
G
D
Q
V
R
V
I
E
G
P
F
M
N
F
T
G
T
V
E
E
V
H
P
E
K
R
K
L
T
V
M
-
I
S
I
F
-------
G
R
M
T
P
V
E
L
D
F
D
Q
V
E
K
I
---
26
HHSearch
61.81
29%
-87
* C3 *
2XHC
-
NUSG_THEMA
A:
[166-352]
-----------------------------------------------------------------------------------------------
D
G
E
Q
D
V
Y
Y
I
P
L
DVFDRD
R
I
K
K
G
K
E
V
K
Q
G
E
M
L
A
E
----
A
R
K
F
-----
F
A
K
V
-
S
G
R
V
E
V
V
D
-----
Y
S
T
R
K
---------------
E
-
I
R
I
Y
K
-----------------------------------------------------------------
T
K
R
R
K
L
F
P
G
Y
V
F
V
E
M
I
M
N
D
-----
E
A
Y
N
F
V
R
S
V
P
Y
V
M
---
G
F
V
S
S
G
G
-
Q
P
V
P
V
K
D
R
E
M
R
P
I
L
R
--
L
A
G
L
E
E
Y
------------
E
L
G
F
K
V
G
D
M
V
K
I
I
S
G
P
F
E
D
F
A
G
V
I
K
E
I
D
P
E
R
Q
E
L
K
V
N
-
V
T
I
F
-------
G
R
E
T
P
V
V
L
H
V
S
E
V
E
K
I
---
4
PsiBlast_PDB
60.72
31%
-98
- C3 -
1M1G
-
NUSG_AQUAE
A:
[127-248]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
I
-----------------------------------------------------------------
V
L
D
N
K
I
F
P
G
Y
I
L
I
K
A
H
M
N
D
-----
K
L
L
M
A
I
E
K
T
P
H
---
V
F
R
P
V
M
V
G
G
-
K
P
V
P
L
K
E
E
E
V
Q
N
I
L
N
--
Q
I
K
R
G
V
K
P
-----
S
K
---
V
E
--
F
E
K
G
D
Q
V
R
V
I
E
G
P
F
M
N
F
T
G
T
V
E
E
V
H
P
E
K
R
K
L
T
V
M
-
I
S
I
F
-------
G
R
M
T
P
V
E
L
D
F
D
Q
V
E
K
I
---
6
PsiBlast_PDB
60.10
31%
-96
- C3 -
1NPR
-
NUSG_AQUAE
A:
[127-248]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
I
-----------------------------------------------------------------
V
L
D
N
K
I
F
P
G
Y
I
L
I
K
A
H
M
N
D
-----
K
L
L
M
A
I
E
K
T
P
H
---
V
F
R
P
V
M
V
G
G
-
K
P
V
P
L
K
E
E
E
V
Q
N
I
L
N
--
Q
I
K
R
G
V
K
P
-----
S
K
---
V
E
--
F
E
K
G
D
Q
V
R
V
I
E
G
P
F
M
N
F
T
G
T
V
E
E
V
H
P
E
K
R
K
L
T
V
M
-
I
S
I
F
-------
G
R
M
T
P
V
E
L
D
F
D
Q
V
E
K
I
---
21
PsiBlast_CBE
59.51
31%
-100
- C3 -
1NPP
1
NUSG_AQUAE
D:
[127-245]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
I
-----------------------------------------------------------------
V
L
D
N
K
I
F
P
G
Y
I
L
I
K
A
H
M
N
D
-----
K
L
L
M
A
I
E
K
T
P
H
---
V
F
R
P
V
M
V
G
G
-
K
P
V
P
L
K
E
E
E
V
Q
N
I
L
N
--
Q
I
K
R
G
V
K
P
-----
S
K
---
V
E
--
F
E
K
G
D
Q
V
R
V
I
E
G
P
F
M
N
F
T
G
T
V
E
E
V
H
P
E
K
R
K
L
T
V
M
-
I
S
I
F
-------
G
R
M
T
P
V
E
L
D
F
D
Q
V
------
49
Fugue
58.04
18%
-64
- C1 -
4LL1
-
TXNIP_HUMAN
A:
[5-296]
--------
I
K
S
F
E
V
V
F
N
D
P
E
K
V
Y
G
--
S
G
E
K
V
A
G
R
V
I
V
E
V
C
E
V
T
R
V
K
A
V
R
I
L
A
C
G
V
A
K
V
L
W
M
Q
-----------
G
S
Q
Q
C
K
Q
T
S
E
Y
L
R
Y
E
D
T
L
L
L
E
D
Q
P
T
G
E
N
E
M
V
I
M
------
R
P
G
N
K
Y
E
Y
K
F
G
F
E
L
P
Q
----
G
P
L
GTSFKG
K
Y
G
S
V
D
Y
W
V
K
A
F
L
D
R
P
SQ
P
T
Q
E
T
K
K
N
F
E
V
VPDLM
A
P
V
S
A
-
K
K
E
K
K
-----------------------------------------------------------------
V
S
S
M
F
I
P
D
G
R
V
S
V
S
A
R
I
D
R
-----
K
G
F
C
E
G
D
----
E
I
S
I
H
A
D
F
E
N
T
S
-
S
R
I
V
V
P
K
A
A
I
V
A
R
H
T
--
Y
L
A
N
G
-
Q
T
-----
K
V
---
L
T
Q
K
L
S
S
V
R
G
N
H
I
I
S
G
T
C
A
S
W
R
G
K
S
L
R
V
Q
-
K
I
N
I
L
R
V
E
-
Y
S
L
L
I
Y
V
S
V
P
G
S
K
K
V
I
L
D
L
P
L
V
I
G
S
-----
8
PsiBlast_PDB
57.72
32%
-115
- C3 -
1NZ8
-
NUSG_THET8
A:
[4-109]
-----------------------------------------------------------------------------------------------------
E
W
Y
A
V
------
H
T
L
V
G
Q
E
E
K
A
K
A
N
L
E
K
----
R
I
K
------
A
F
G
L
Q
D
K
I
F
Q
V
L
I
-----
P
T
E
E
V
V
E
-----------
L
R
E
-
G
G
K
K
E
-----------------------------------------------------------------
V
V
R
K
K
L
F
P
G
Y
L
F
I
Q
M
D
L
G
D
EEEPN
E
A
W
E
V
V
R
G
T
P
---
G
I
T
G
F
V
G
A
G
M
-
R
P
V
P
L
S
P
D
E
V
R
H
I
L
E
--
V
S
G
L
L
G
---------------------------------------------------------------------------------
45
Fugue
56.38
20%
-84
- C3 -
1M1H
-
NUSG_AQUAE
A:
[5-186]
QV
Q
E
L
E
K
K
W
Y
A
L
Q
V
E
P
G
K
E
N
E
A
K
E
N
L
L
K
V
L
E
L
E
G
L
-------------
K
D
L
V
D
E
V
I
V
----------
P
A
E
E
K
V
V
I
R
A
Q
G
K
E
K
Y
R
L
S
L
K
G
--
N
A
R
D
I
S
V
L
G
K
K
G
V
T
T
------
F
R
I
E
N
G
E
V
K
V
V
E
S
V
E
G
----
D
T
C
------
V
N
-----
A
P
P
I
S
K
-----
P
G
Q
K
I
T
C
-----------
K
E
N
K
T
E
A
K
I
-----------------------------------------------------------------
V
L
D
N
K
I
F
P
G
Y
I
L
I
K
A
H
M
N
D
-----
K
L
L
M
A
I
E
K
T
P
H
---
V
F
R
P
V
M
V
G
G
-
K
P
V
P
L
K
E
E
E
V
Q
N
I
L
N
--
Q
I
K
R
-----------------------------------------------------------------------------------
46
Fugue
55.20
19%
-94
- C3 -
2OUG
-
RFAH_ECOLI
A:
[2-156]
----------------------------------------------------------------------------------------------------
Q
S
W
Y
L
L
------
Y
C
K
R
G
Q
L
Q
R
A
Q
E
H
L
E
R
----
Q
A
V
---------------
N
C
L
A
-----
P
M
I
T
L
E
K
-----------
I
V
--
R
G
K
R
T
-----------------------------------------------------------------
A
V
S
E
P
L
F
P
N
Y
L
F
V
E
F
D
P
E
V
-----
I
H
T
T
T
I
N
A
T
R
G
---
V
S
H
F
V
R
F
G
A
-
S
P
A
I
V
P
S
A
V
I
H
Q
L
S
V
---------------------------
Y
K
K
V
I
I
T
E
G
A
F
E
G
F
Q
A
I
F
T
E
P
D
G
E
A
R
S
M
L
L
--
L
N
L
I
-------
N
K
E
I
K
H
S
V
K
N
---------
23
HHSearch
52.72
18%
-89
- C3 -
2OUG
-
RFAH_ECOLI
A:
[2-156]
----------------------------------------------------------------------------------------------------
Q
S
W
Y
L
L
------
Y
C
K
R
G
Q
L
Q
R
A
Q
E
H
L
E
R
----
Q
A
V
---------------
N
C
L
A
-----
P
M
I
T
L
E
K
-----------
I
V
--
R
G
K
R
T
-----------------------------------------------------------------
A
V
S
E
P
L
F
P
N
Y
L
F
V
E
F
D
P
E
V
-----
I
H
T
T
T
I
N
A
T
R
G
V
S
---
H
F
V
R
F
G
A
-
S
P
A
I
V
P
S
A
V
I
H
Q
L
S
V
--
Y
K
-------------------------
K
V
I
I
T
E
G
A
F
E
G
F
Q
A
I
F
T
E
P
D
G
E
A
-
R
S
M
L
L
-
L
N
L
I
-------
N
K
E
I
K
H
S
V
K
N
---------
35
HHSearch
50.11
16%
-106
- C3 -
3LPE
-
SPT5_METJA
A:
[9-90]
---------------------------------------------------------------------------------------------------
A
H
M
I
F
A
V
------
R
T
M
V
G
Q
E
K
N
I
A
G
L
M
A
S
----
R
A
E
---------------
K
E
-------
Q
---------------------
L
D
V
Y
S
-----------------------------------------------------------------
I
L
A
S
E
S
L
K
G
Y
V
L
V
E
A
E
T
K
G
-----
D
V
E
E
L
I
K
G
M
P
R
V
R
---
G
I
------
V
P
G
T
I
A
I
E
E
I
E
P
L
L
T
--
P
--------------------------------------------------------------------------------------