@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Wbm0693: (2015-12-03 )
MMAHIKEASDTNFSEMYGSLFPSKENGKGTWIDWKAAFKQQKLLEAESNVMLLEISYSLLKENQLYKEEVGTKLDNIIKNNQGNVRKGRQIC
Atome Classification :
(20 SA)
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------........--.10........20........30.-.---.---.....40......-.-----.50..-.....---.60.......-.70.-----.......80...----.....90.------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMAHIKEA--SDT
N
F
S
E
M
Y
G
S
LFPSKENGKG
T
W
I
-
D
---
W
---
K
A
A
F
K
Q
Q
K
L
LEAE-S-----
N
V
M
L
L
-
E
I
S
Y
S
---
L
L
K
E
N
Q
L
Y
K
E
-
E
V
G
T
-----
K
L
D
N
I
I
KNNQGN----VRKGRQIC------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
Fugue
83.62
22%
1
- C5 -
4BUJ
3
SKI3_YEAST
B:
[3-1436]
DS
M
S
D
I
K
Q
L
L
K
E
A
K
Q
E
L
T
N
RD
Y
E
E
T
I
E
I
S
E
K
V
L
K
L
D
PDN
Y
F
A
H
I
F
L
G
K
A
L
S
S
LPASN
N
V
S
S
N
R
N
L
E
R
A
T
N
H
Y
V
S
A
A
K
L
V
PDN
L
L
A
W
K
G
L
F
L
L
F
R
T
T
E
V
V
P
D
I
L
S
Y
D
E
Y
F
D
L
C
G
Q
Y
A
D
A
L
L
K
Q
EQ
V
E
L
I
N
D
I
K
L
L
K
K
T
H
PDC
Q
K
A
F
Y
Q
H
L
KPGS
L
M
A
E
T
IGRT
P
Q
D
A
L
L
N
L
I
K
I
L
S
N
I
E
T
T
E
I
G
K
T
L
S
Q
N
R
L
K
LKASDPD
Y
Q
I
K
L
N
S
F
S
W
E
I
I
K
N
SE
I
D
Q
L
Y
N
Q
L
V
N
I
LADD
Q
K
R
S
E
I
E
N
Q
W
L
E
Y
R
I
K
V
L
K
S
MP
L
D
V
K
K
D
F
F
T
K
V
K
E
M
V
E
D
M
V
L
V
NHQS
L
L
A
W
Q
K
Y
F
E
W
TDYEDLDNMDA
P
L
I
I
K
Y
F
K
K
FPKD
P
L
A
M
I
L
Y
S
W
L
S
SKLSKYD
I
K
S
L
E
SDDIEIGLL
E
E
E
V
V
T
V
L
T
E
N
I
V
K
C
KNN
I
L
A
H
R
I
L
C
Q
Y
Y
L
L
T
KEYEAA
L
P
Y
I
K
N
G
I
S
L
I
A
Y
N
I
K
D
LGVHL
P
L
T
K
R
E
F
S
L
D
L
A
T
V
Y
T
YVDAPKD
H
N
A
A
L
K
L
Y
D
N
I
L
S
G
DF
S
N
I
Q
A
K
M
G
K
G
I
I
F
I
E
R
K
N
----
W
K
-
D
---
A
---
M
T
L
L
T
Q
V
H
E
Q
S
P
N
-
N
-----
L
E
V
L
S
-
E
L
S
W
S
---
K
A
H
M
G
--
Y
M
D
-
E
A
L
A
-----
G
L
D
T
V
I
K
G
I
K
G
M
----
D
L
R
S
I
D
F
R
A
L
N
L
W
R
Q
A
K
V
Y
I
M
K
H
A
SAKQE
N
V
K
C
A
F
K
L
L
I
Q
S
I
K
I
LDTF
A
P
G
F
S
T
L
G
D
I
Y
C
HYYKD
H
L
R
A
F
K
C
Y
F
K
A
F
D
L
DAGD
Y
T
A
A
K
Y
I
T
E
T
Y
A
S
K
PN
W
Q
A
A
S
S
I
A
S
R
L
I
K
G
EKA
K
A
E
L
R
S
NN
W
P
F
R
V
V
G
I
A
H
L
E
K
QE
E
S
D
S
I
E
W
F
Q
S
A
L
R
V
DPND
V
E
S
W
V
G
L
G
Q
A
Y
H
A
C
GR
I
E
A
S
I
K
V
F
D
K
A
I
Q
L
RPSH
T
F
A
Q
Y
F
K
A
I
S
L
C
D
V
GE
Y
L
E
S
L
D
I
L
E
K
V
C
Q
E
AATEE
S
F
Q
I
G
L
V
E
V
L
M
R
C
S
L
D
L
Y
S
Q
GF
L
L
K
S
V
S
I
A
K
D
T
I
E
R
I
K
I
I
I
S
E
LKCENQQ
V
W
I
Y
L
S
Q
V
L
R
L
F
I
W
I
ESKVDTLP
V
E
S
L
V
S
I
F
E
N
S
QFSGS
E
E
I
D
S
V
DNIKIDTLLDSTTDD
N
V
S
I
A
C
K
F
L
I
L
A
S
K
Y
SVSDQK
F
T
D
I
AG
T
V
R
A
S
Y
W
Y
N
I
G
I
S
E
L
T
A
F
I
T
L
KE
P
Q
Y
R
D
A
A
I
F
A
F
K
K
S
I
Q
L
QSNT
S
E
T
W
I
G
L
G
I
A
T
MDIN
F
R
V
S
Q
H
C
F
I
K
A
T
A
L
EPKA
T
N
T
W
F
N
L
A
M
L
G
L
K
K
KD
T
E
F
A
Q
Q
V
L
N
K
L
Q
S
L
APQD
S
S
P
W
L
G
M
A
L
I
L
E
E
Q
GD
I
I
G
S
S
K
L
F
A
H
S
F
I
L
S
N
GRS
K
A
A
Q
F
M
Y
A
K
N
V
L
E
N
HINNGDDERD
I
E
T
V
E
K
L
T
T
A
S
I
A
L
E
Q
F
F
K
K
SPDS
Q
F
A
L
Q
C
A
L
L
T
L
E
R
L
HH
Y
E
N
A
N
E
L
A
N
R
L
I
G
I
L
E
K
K
F
E
K
TQD
E
R
E
L
F
N
F
A
I
I
K
G
Q
F
A
R
I
H
L
G
L
GN
F
E
L
S
I
E
N
A
D
L
S
Q
G
I
I
SESSD
E
K
S
M
K
T
K
I
S
N
H
I
C
L
G
L
S
Y
F
F
L
NDF
D
Q
T
L
N
Q
F
Q
E
L
L
S
I
S
KDS
K
H
L
V
V
L
I
A
K
V
L
Y
D
V
GE
S
D
T
K
E
I
A
L
Q
E
L
T
E
Y
I
A
T
SGADL
L
V
T
L
T
I
A
A
M
S
I
L
D
DK
R
E
D
L
S
I
I
L
E
E
L
K
A
LP
L
S
K
Q
I
I
DKHK
D
A
P
Y
L
I
E
E
I
T
K
R
L
YRNDTGK
Q
V
W
Q
R
S
A
Y
F
FPNN
L
K
V
W
E
R
LD
K
N
I
Q
R
R
I
A
SNGQ
N
K
V
T
A
E
E
M
S
K
L
Y
C
E
S
KN
L
R
S
I
Q
R
G
M
F
L
C
PWN
V
T
A
V
K
A
L
N
E
C
F
36
Fugue
64.40
15%
-13
- C5 -
4QIQ
1
XYLE_ECOLI
A:
[7-470]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S
Y
I
F
S
I
T
L
V
A
T
L
G
G
L
L
F
G
Y
D
T
A
VISGT
V
E
S
L
N
T
V
FVAPQNLS
E
S
A
A
N
S
L
L
G
F
C
V
A
S
A
L
I
G
C
I
I
G
G
A
L
G
G
Y
C
S
N
RFG
R
R
D
S
L
K
I
A
A
V
L
F
F
I
S
G
V
G
S
A
WPELGFTSINPDNTVPVYLAGY
V
P
E
F
V
I
Y
R
I
I
G
G
I
G
V
G
L
A
S
M
L
S
P
M
Y
I
A
E
LAPAHI
R
G
K
L
V
S
F
N
Q
F
A
--
I
I
F
G
Q
L
L
V
Y
C
V
N
Y
F
I
A
R
S
G
D
A
S
W
L
-
N
T
D
G
W
---
R
Y
M
F
A
S
E
C
I
P
A
L
L
-
F
-----
L
M
L
L
Y
-
T
V
P
E
S
PRW
L
M
T
L
A
T
Q
A
V
Q
-
E
I
K
H
-----
S
L
D
R
L
L
M
F
G
V
G
V
----
I
V
I
G
V
M
L
S
I
F
Q
Q
F
V
G
I
N
V
V
L
Y
Y
A
P
E
V
F
K
T
L
GAS
T
D
I
A
L
L
Q
T
I
I
V
G
V
I
N
L
T
F
T
V
L
A
I
M
T
V
DKFGRKP
L
Q
I
I
G
A
L
G
M
A
I
G
M
F
S
L
G
T
A
F
Y
T
QAP
G
I
V
A
L
L
S
M
L
F
Y
V
A
A
F
A
M
SWGP
V
C
W
V
L
L
S
E
I
F
PNA
I
R
G
K
A
L
A
I
A
V
A
A
Q
W
L
A
N
Y
F
V
S
W
T
FPMMDKN
S
W
L
V
A
H
FHNGF
S
Y
W
I
Y
G
C
M
G
V
L
A
A
L
F
M
W
KFVPETKGKTL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
PsiBlast_PDB
63.96
35%
-23
- C5 -
3FOC
1
?
A:
[401-440]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
A
D
Y
K
T
G
K
L
L
T
G
E
-
V
-----
K
A
T
L
I
-
G
I
L
Q
G
---
L
I
K
E
H
A
E
R
R
D
-
K
V
D
T
-----
T
M
I
E
S
F
T
V
K
K
E
L
----
Q
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
60.09
28%
-25
- C7 -
4ZCH
1
TN13B_HUMAN (first)
A:
[158-206]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
T
I
Q
K
G
S
Y
T
F
V
-
P
---
W
---
L
L
S
F
K
R
G
S
A
L
E
E
K
-
E
-----
N
K
I
L
V
K
E
T
G
Y
F
---
F
I
Y
G
Q
V
L
Y
T
D
-
K
T
Y
A
-----
M
G
H
L
I
Q
R
K
K
V
H
V
----
F
G
D
E
L
S
L
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
58.07
28%
-17
- C7 -
3V56
1
TN13B_HUMAN
A:
[79-128]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
T
I
Q
K
G
S
Y
T
F
V
-
P
---
W
---
L
L
S
F
K
R
G
S
A
L
E
E
K
-
E
-----
N
K
I
L
V
K
E
T
G
Y
F
---
F
I
Y
G
Q
V
L
Y
T
D
-
K
T
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
56.46
28%
-27
- C7 -
1OQE
-
TN13B_HUMAN
A:
[15-63]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
T
I
Q
K
G
S
Y
T
F
V
-
P
---
W
---
L
L
S
F
K
R
G
S
A
L
E
E
K
-
E
-----
N
K
I
L
V
K
E
T
G
Y
F
---
F
I
Y
G
Q
V
L
Y
T
D
-
K
T
Y
A
-----
M
G
H
L
I
Q
R
K
K
V
H
V
----
F
G
D
E
L
S
L
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
55.73
28%
-24
- C7 -
1OSG
1
TN13B_HUMAN
A:
[79-128]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
T
I
Q
K
G
S
Y
T
F
V
-
P
---
W
---
L
L
S
F
K
R
G
S
A
L
E
E
K
-
E
-----
N
K
I
L
V
K
E
T
G
Y
F
---
F
I
Y
G
Q
V
L
Y
T
D
-
K
T
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
Fugue
55.19
16%
25
- C4 -
1I8N
2
LAPP_HAEOF
A:
[37-125]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
T
I
T
A
G
--
N
E
D
C
W
S
K
R
P
G
W
K
L
P
D
N
L
L
T
K
T
E
F
T
-
S
---
V
---
D
E
C
R
K
M
C
E
E
S
A
V
E
-
P
-----
S
C
Y
I
L
-
Q
I
N
T
E
------
T
N
E
C
Y
R
N
N
E
G
D
V
-----
T
W
S
S
L
Q
Y
D
Q
P
N
V
----
V
Q
W
H
L
H
A
C
S-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
55.01
28%
-22
- C7 -
1OQD
-
TN13B_HUMAN
A:
[15-63]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
T
I
Q
K
G
S
Y
T
F
V
-
P
---
W
---
L
L
S
F
K
R
G
S
A
L
E
E
K
-
E
-----
N
K
I
L
V
K
E
T
G
Y
F
---
F
I
Y
G
Q
V
L
Y
T
D
-
K
T
Y
A
-----
M
G
H
L
I
Q
R
K
K
V
H
V
----
F
G
D
E
L
S
L
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
54.50
28%
-18
* C7 *
1JH5
-
TN13B_HUMAN
A:
[15-63]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
T
I
Q
K
G
S
Y
T
F
V
-
P
---
W
---
L
L
S
F
K
R
G
S
A
L
E
E
K
-
E
-----
N
K
I
L
V
K
E
T
G
Y
F
---
F
I
Y
G
Q
V
L
Y
T
D
-
K
T
Y
A
-----
M
G
H
L
I
Q
R
K
K
V
H
V
----
F
G
D
E
L
S
L
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
54.36
29%
-17
- C7 -
1KXG
3
TN13B_HUMAN
A:
[23-70]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
T
I
Q
K
G
S
Y
T
F
V
-
P
---
W
---
L
L
S
F
K
R
G
S
A
L
E
E
K
-
E
-----
N
K
I
L
V
K
E
T
G
Y
F
---
F
I
Y
G
Q
V
L
Y
T
D
-
K
T
Y
A
-----
M
G
H
L
I
Q
R
K
K
V
H
V
----
F
G
D
E
L
S
L
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
Fugue
53.88
12%
-17
- C5 -
3J6V
-
RT21_BOVIN
U:
[1-87]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
A
K
H
L
K
F
I
--
A
R
T
V
M
V
Q
--
E
G
N
V
E
G
A
Y
R
T
L
N
R
I
L
-
T
---
M
---
D
G
L
I
E
D
I
K
R
R
R
Y
Y
-
E
-----
K
P
C
R
R
-
R
Q
R
E
S
---
Y
E
T
C
R
R
I
Y
N
M
-
E
M
A
R
-----
K
I
N
F
L
M
R
K
N
R
A
D
----
P
W
Q
G
C
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
53.68
29%
-7
- C7 -
1KD7
-
TN13B_HUMAN
A:
[156-203]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
T
I
Q
K
G
S
Y
T
F
V
-
P
---
W
---
L
L
S
F
K
R
G
S
A
L
E
E
K
-
E
-----
N
K
I
L
V
K
E
T
G
Y
F
---
F
I
Y
G
Q
V
L
Y
T
D
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
Fugue
53.16
15%
13
- C2 -
2JOZ
-
YXEF_BACSU
A:
[1-135]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M
I
M
V
S
G
C
Q
Q
--
Q
K
E
E
T
P
F
Y
Y
G
T
W
D
E
G
R
A
P
G
P
T
D
G
V
K
S
---
A
---
T
V
T
F
T
E
D
E
V
V
E
T
E
-
V
M
EGR
G
E
V
Q
L
P
-
F
M
A
Y
K
---
V
I
S
Q
S
T
D
G
S
I
-
E
I
Q
Y
L
G
PYY
P
L
K
S
T
L
K
R
G
E
N
G
T
L
I
W
E
Q
N
G
Q
R
K
T
M
T
R
I
E
S
KTG
R
E
E
K
D
E
K
S
K
S
LEHHHHHH---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
Fugue
48.43
16%
-0
- C5 -
2F95
-
HTR2_NATPH
B:
[24-76]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
F
V
G
A
L
--
T
V
L
F
G
A
I
A
Y
G
E
V
T
A
A
A
A
T
G
D
-------------
A
A
A
V
Q
E
A
A
V
S
A
I
L
-
G
-----
L
I
I
L
L
-
G
I
N
L
G
---
L
V
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
47.58
27%
-36
- C5 -
2DVY
-
?
A:
[51-98]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
P
S
D
E
N
L
R
D
Y
Y
I
-
E
---
W
---
Q
I
S
Y
A
R
D
G
K
Y
D
Y
E
L
S
-----
R
M
V
R
L
-
A
H
E
H
G
---
I
L
T
Y
N
D
I
Y
E
L
-
L
K
F
A
-----
D
D
V
K
S
Y
L
E
D
K
G
I
----
R
R
E
S
T
N
E
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
HHSearch
47.26
22%
-12
- C5 -
3MI9
-
CDK9_HUMAN
A:
[328-344]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
S
T
H
L
T
S
M
F
E
Y
L
A
P
P
R
R
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
46.50
27%
-33
- C5 -
3WAZ
2
?
A:
[45-92]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
P
S
D
E
N
L
R
D
Y
Y
I
-
E
---
W
---
Q
I
S
Y
A
R
D
G
K
Y
D
Y
E
L
S
-----
R
M
V
R
L
-
A
H
E
H
G
---
I
L
T
Y
N
D
I
Y
E
L
-
L
K
F
A
-----
D
D
V
K
S
Y
L
E
D
K
G
I
----
R
R
E
S
T
N
E
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34
Fugue
44.83
19%
8
- C5 -
1H2S
-
HTR2_NATPH
B:
[1-60]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
--
A
V
F
I
F
V
G
A
L
T
V
L
F
G
A
I
A
Y
G
E
V
T
A
A
-
A
---
A
T
GD
A
A
A
V
Q
E
A
A
V
S
A
I
L
-
G
-----
L
I
I
L
L
-
G
I
N
L
G
---
L
V
A
A
T
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
44.04
26%
5
- C5 -
2EV4
1
Y1264_MYCTU
A:
[23-46]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
N
I
D
D
L
L
G
D
L
G
G
T
A
R
A
E
R
A
K
L
V
-
E
---
W
---
L
L
E
Q
G
I
T
P
D
E
I
R
A
-
T
-----
N
P
P
L
L
-
L
A
T
R
H
---
L
V
G
D
D
G
T
Y
V
S
-
A
R
E
I
-----
S
E
N
Y
G
V
D
L
E
L
L
Q
----
R
V
Q
R
A
V
G
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------