@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Wbm0728: (2015-12-04 )
MKSILLTRPLSDSLNTRSTLKKYGYKVYIEPAFTIKHLQPDISAYKFDVVISTSKNSVKAFSQICRVDDLPIITVGNSTMQTAKDSGFSDIISADSNVEGLISFVKNYYSRAVKFLYIRGQEVSCDLKKRLSEEGFNVREVILYKTIIKRGLTNRCKNLLLGGRINSVAFFSSQTARIFCSLVLKSGLSNVMDNITAYAMSKNIVDSLKPIKWKKIITSRLPTQENLIDIINKDC
Atome Classification :
(20 SA)
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.........10.----....---...20........30.....-----...40------.-----.-------.-......50......-..60...-------.-------------.---------------...70........80........90.-...-.....100......---.110..--.....120.-------.--------.....130.......140.......150.-...-....160-.-----.......170.......180.--......--190........200.......-----210.......220........230...--------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MK
S
I
L
LTRPLSD----SL
N
T
---
R
S
T
L
K
KY
G
Y
K
V
Y
IE
P
A
F
T
I
K
-----HLQP-------D-----I-------S-
A
Y
K
F
D
V
V
I
STSK
N
S
-
V
K
A
F
S
Q
I
-------C-------------R---------------VDDL
P
I
I
T
VGNS
T
M
QTAKDSG
F
S
D
-
I
-ISA-DS
N
V
E
G
L
I
S
F
V
K
N
Y
---
Y
S
R
A
V
K
--
F
L
Y
I
RGQEV-------
S
--------
C
D
L
K
K
R
L
S
EEGF
N
V
R
E
V
I
L
Y
K
T
I
I
K
R
G
-
L
-
T
N
R
-
C
K
N
LL-L-G-----GRI
N
S
V
A
F
FSS
Q
T
A
R
I
F
C
S
L
V
--
L
K
S
G
L
S
--
N
-
V
M
D
N
I
T
A
Y
A
M
S
K
N
I
V
D
SLK-----P
I
K
W
K
K
I
I
T
SR-LP
T
Q
E
N
L
I
D
I
INKDC--------------------------------------------------------------------------------------------------------------------------------------------
42
Fugue
93.07
19%
-100
- C5 -
1JR2
-
HEM4_HUMAN
A:
[1-260]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
K
V
L
L
L
K
D
A
K
E
D
----
D
C
G
Q
D
P
Y
I
R
E
L
G
L
Y
G
L
E
A
T
L
I
P
V
L
S
F
E
F
L
S
L
P
S
F
S
E
-------
K
-----
L
S
------
H
-
P
E
D
Y
G
G
L
I
F
T
S
P
R
A
-
V
E
A
A
E
L
C
-------
L
-------------
E
Q
N
NK
T
E
V
W
E
R
SL
K
E
K
W
N
A
K
S
V
Y
V
V
G
N
A
T
A
S
L
V
S
K
I
G
L
D
T
-
E
-
G
E
T
-
C
G
N
A
E
K
L
A
E
Y
I
C
S
R
---
E
S
S
A
L
P
--
L
L
F
P
C
G
N
L
K
-------
R
--------
E
I
L
P
K
A
L
K
D
K
G
I
A
M
E
S
I
T
V
Y
Q
T
V
A
H
P
G
-
I
-
Q
G
N
-
L
N
S
Y
Y
-
S
-
Q
-----
Q
G
V
P
A
S
I
T
F
F
S
P
S
G
L
T
Y
S
L
K
H
--
I
Q
E
L
S
G
--
D
-
N
I
D
Q
I
K
F
A
A
I
G
P
T
T
A
R
A
L
A
-----
A
Q
G
L
P
V
S
C
T
A
E
-
S
P
T
P
Q
A
L
A
T
G
I
R
K
A
L
Q-------------------------------------------------------------------------------------------------------------------------------------------
23
HHSearch
92.67
20%
-96
- C5 -
1JR2
-
HEM4_HUMAN
A:
[1-258]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
K
V
L
L
L
K
D
A
K
E
D
D
CG
Q
D
P
Y
---
I
R
E
L
G
L
Y
G
L
E
A
T
L
I
P
V
L
S
F
E
-----
F
L
S
L
-------
P
S
F
S
E
K
L
S
------
H
-
P
E
D
Y
G
G
L
I
F
T
S
P
R
A
-
V
E
A
A
E
L
C
L
E
-----
Q
N
NK
T
E
V
W
E
R
SL
K
E
K
---------------
W
N
A
K
S
V
Y
V
V
G
N
A
T
A
S
L
V
S
K
I
G
L
D
T
-
E
-
G
E
T
-
C
G
N
A
E
K
L
A
E
Y
I
C
S
R
---
E
S
S
A
L
P
--
L
L
F
P
C
G
N
L
K
-------
R
--------
E
I
L
P
K
A
L
K
D
K
G
I
A
M
E
S
I
T
V
Y
Q
T
V
A
H
P
G
-
I
-
Q
G
N
-
L
N
S
Y
Y
S
Q
-
Q
-----
G
V
P
A
S
I
T
F
F
S
P
S
G
L
T
Y
S
L
K
H
I
--
Q
E
L
S
G
D
----
N
I
D
Q
I
K
F
A
A
I
G
P
T
T
A
R
A
L
A
-----
A
Q
G
L
P
V
S
C
T
A
E
-
S
P
T
P
Q
A
L
A
T
G
I
R
K
A
L
--------------------------------------------------------------------------------------------------------------------------------------------
21
HHSearch
90.33
19%
-93
- C5 -
3RE1
-
?
A:
[3-250]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
W
R
L
L
L
T
R
P
A
E
E
----
S
A
A
L
---
A
R
V
L
A
D
A
G
I
F
S
S
S
L
P
L
L
E
T
E
-----
P
L
P
L
-------
T
-----
P
A
Q
R
S
I
I
F
E
-
L
L
N
Y
S
A
V
I
V
V
S
K
P
A
-
A
R
L
A
I
E
L
I
------
D
E
VWP---------
Q
---------------
P
P
M
Q
P
W
F
S
V
G
S
A
T
G
Q
I
L
L
D
Y
G
L
D
A
-
S
W
P
--------
A
L
L
D
H
P
R
L
K
Q
A
I
A
V
P
G
S
R
--
V
L
I
M
R
G
N
E
G
-------
R
--------
E
L
L
A
E
Q
L
R
E
R
G
V
G
V
D
Y
L
P
L
Y
R
R
Y
L
P
Q
H
-
A
-
P
G
T
-
L
L
Q
R
V
-
E
-
V
-----
E
R
L
N
G
L
V
V
S
S
G
Q
G
F
E
H
L
L
Q
L
A
--
G
D
S
W
----
P
-
D
L
A
G
L
P
L
F
V
P
S
P
R
V
A
S
L
A
Q
-----
A
A
G
A
R
N
V
I
D
C
R
-
G
A
S
A
A
A
L
L
A
A
L
R
D
Q
P
--------------------------------------------------------------------------------------------------------------------------------------------
22
HHSearch
85.96
16%
-92
- C5 -
3MW8
12
?
A:
[1-239]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
M
K
L
L
L
T
R
P
E
G
K
----
N
A
A
M
---
A
S
A
L
D
A
L
A
I
P
Y
L
V
E
P
L
L
S
V
E
-----
A
A
A
V
-------
T
-----
Q
A
Q
L
D
---
E
-
L
S
R
A
D
I
L
I
F
I
S
T
S
A
-
V
S
F
A
T
P
W
LK-----
D
-------------
Q
---------------
W
P
K
A
T
Y
Y
A
V
G
D
A
T
A
D
A
L
A
L
Q
G
I
T
A
E
R
-
S
P
---
Q
A
T
E
G
L
L
T
L
P
S
L
E
---
Q
V
S
G
K
Q
--
I
V
I
V
R
G
K
G
G
-------
R
--------
E
A
M
A
D
G
L
R
L
R
G
A
N
V
S
Y
L
E
V
Y
Q
R
A
C
P
P
L
-
D
-
A
P
A
-
S
V
S
R
W
-
Q
-
S
-----
F
G
I
D
T
I
V
V
T
S
G
E
V
L
E
N
L
I
N
L
V
--
P
K
D
S
F
A
----
W
L
R
D
C
H
I
I
V
P
S
A
R
V
E
T
Q
A
R
-----
K
K
G
L
R
R
V
T
N
A
G
-
A
A
N
Q
A
A
V
L
D
A
L
G
M
----------------------------------------------------------------------------------------------------------------------------------------------
25
HHSearch
78.75
15%
-82
- C5 -
1WCW
1
?
A:
[8-255]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
V
R
V
A
Y
A
G
L
R
-
R
----
K
E
A
F
---
K
A
L
A
E
K
L
G
F
T
P
L
L
F
P
V
Q
A
T
E
-----
K
V
P
V
-------
P
-----
E
Y
R
D
Q
V
R
-
A
L
A
Q
G
V
D
L
F
L
A
T
T
G
V
G
-
V
R
D
L
L
E
A
G
------
K
A
L
GLD
L
E
------
G
P
--------------
L
A
K
A
F
R
L
A
R
G
A
K
A
A
R
A
L
K
E
A
G
L
P
P
-
H
-
A
V
G
-
D
G
T
S
K
S
L
L
P
L
L
P
Q
G
-----
R
G
V
A
--
A
L
Q
L
Y
G
K
-
P
-------
L
--------
P
L
L
E
N
A
L
A
E
R
G
Y
R
V
L
P
L
M
P
Y
R
H
L
P
D
P
E
-
G
-
I
L
R
-
L
E
E
A
L
-
L
-
R
-----
G
E
V
D
A
L
A
F
V
A
A
I
Q
V
E
F
L
F
E
G
A
--
K
D
P
K
A
L
R
-
E
A
L
N
T
R
V
K
A
L
A
V
G
R
V
T
A
D
A
L
R
-----
E
W
G
V
K
P
F
Y
V
D
E
-
T
E
R
L
G
S
L
L
Q
G
F
K
R
A
L
--------------------------------------------------------------------------------------------------------------------------------------------
24
HHSearch
76.57
15%
-71
- C5 -
3D8T
3
?
A:
[33-281]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
M
R
I
A
Y
A
G
L
R
-
R
----
K
E
E
F
---
K
A
L
A
E
K
L
G
F
T
P
L
L
F
P
V
Q
A
T
E
-----
K
V
P
V
-------
P
-----
E
Y
R
D
Q
V
R
-
E
L
A
Q
G
V
D
L
F
L
A
T
T
G
V
G
-
V
R
D
L
L
E
A
G
------
K
A
L
GLD
L
E
G
-----
P
---------------
L
A
K
A
F
R
L
A
R
G
A
K
A
A
R
A
L
K
E
A
G
L
P
P
-
H
-
A
V
G
-
D
G
T
S
K
S
L
L
P
L
L
P
Q
G
-----
R
G
V
A
--
A
L
Q
L
Y
G
K
-
P
-------
L
--------
P
L
L
E
N
A
L
A
E
R
G
Y
R
V
L
P
L
M
P
Y
R
H
L
P
D
P
E
-
G
-
I
L
R
-
L
E
E
A
V
-
L
-
R
-----
G
E
V
D
A
L
A
F
V
A
A
I
Q
V
E
F
L
F
E
G
A
--
K
D
P
K
A
L
R
E
A
-
L
N
T
R
V
K
A
L
A
V
G
R
V
T
A
D
A
L
R
-----
E
W
G
V
K
P
F
Y
V
D
E
-
T
E
R
L
G
S
L
L
Q
G
F
K
R
A
L
--------------------------------------------------------------------------------------------------------------------------------------------
43
Fugue
74.67
13%
-76
- C5 -
1WD7
-
?
A:
[8-261]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
V
R
V
A
Y
A
G
L
-
R
R
----
K
E
A
F
---
K
A
L
A
E
K
L
G
F
T
P
L
L
F
P
V
Q
A
T
E
-----
K
V
P
V
PE
Y
R
D
Q
V
R
-----
A
-------
L
-
A
Q
G
V
D
L
F
L
A
T
T
G
V
G
-
V
R
D
L
L
E
A
-------
G
-------------
K
A
L
GLD
L
E
G
P
------
L
A
K
A
F
R
L
A
R
G
A
K
A
A
R
A
L
K
E
A
G
L
P
P
-
H
-
A
V
G
-
D
G
T
S
K
S
L
L
P
L
L
P
Q
G
---
R
G
---
V
--
A
A
L
Q
L
Y
G
K
P
-------
L
--------
P
L
L
E
N
A
L
A
E
R
G
Y
R
V
L
P
L
M
P
Y
R
H
L
P
D
P
E
-
G
-
I
L
R
-
L
E
E
A
L
-
L
-
R
-----
G
E
V
D
A
L
A
F
V
A
A
I
Q
V
E
F
L
F
E
G
A
KD
P
K
A
L
R
E
--
A
-
L
N
T
R
V
K
A
L
A
V
G
R
V
T
A
D
A
L
R
-----
E
W
G
V
K
P
F
Y
V
D
E
-
T
E
R
L
G
S
L
L
Q
G
F
K
R
A
L
Q
K
E
V
A---------------------------------------------------------------------------------------------------------------------------------------
26
HHSearch
66.90
16%
-87
- C5 -
3P9Z
1
?
A:
[16-224]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
P
Y
K
T
L
I
L
N
E
F
C
-----
Y
Y
P
L
-------
E
-----
L
-------
D
-
P
T
P
F
N
A
L
I
F
T
S
K
N
A
-
V
F
S
L
L
E
T
L
KNS
P
K
L
K
-------------
M
---------------
L
Q
N
I
P
A
Y
A
L
S
E
P
T
A
K
T
L
Q
D
H
H
F
K
V
A
F
-
M
G
E
----------
E
I
F
P
L
----
L
E
K
K
S
--
V
L
Y
L
R
A
K
E
I
-------
V
--------
S
S
L
D
T
I
L
L
E
H
G
I
D
F
K
Q
A
V
V
Y
E
N
K
L
K
H
L
-
T
-
L
S
--
E
Q
N
A
L
-
K
-
P
-----
K
E
K
S
I
L
I
F
T
A
I
S
H
A
K
A
F
L
H
Y
F
--
E
F
---------
L
E
N
Y
T
A
I
S
I
G
N
T
T
A
L
Y
L
Q
-----
E
Q
G
I
P
S
-
Y
I
A
K
-
K
P
S
L
E
A
C
L
E
L
A
L
S
L
R
--------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
59.59
23%
-121
- C4 -
3P9Z
1
?
A:
[38-148]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
N
A
L
I
F
T
S
K
N
A
-
V
F
S
L
L
E
T
-------
L
-------------
K
NS
P
K
L
K
M
--------
L
Q
N
I
P
A
Y
A
L
S
E
P
T
A
K
T
L
Q
D
H
H
F
K
V
-
A
-
F
M
G
-
E
-----------
E
I
---
F
P
L
L
E
K
KS
V
L
Y
L
R
A
K
E
I
-------
V
--------
S
S
L
D
T
I
L
L
E
H
G
I
D
F
K
Q
A
V
V
Y
E
N
K
L
K
H
L
-
T
-
L
S
E
-
Q
N
A
L
K
-
P
-
K
-----
E
K
S
I
L
I
F
T
A
I
S
H
A
K
A
F
L
H
Y
F
E
--
F
L
E
N
Y
T
--
A
-
I
S
I
G
N
T
T
A
L
Y
L
Q
E
Q
G
I
P
S
Y
-----
I
A
K
K
P
S
L
E
A
C
L
-
E
L
A
L
S
L
R
----------------------------------------------------------------------------------------------------------------------------------------------------
40
HHSearch
57.68
12%
-91
- C5 -
3K9C
1
?
A:
[33-225]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
---
Y
A
A
A
T
R
R
G
Y
D
V
M
L
S
A
V
A
P
S
R
-----
A
E
K
V
-------
A
-----
V
Q
A
L
----
M
-
R
E
R
C
E
A
A
I
L
L
G
T
R
F
D
T
D
E
L
G
A
----------------------
L
---------------
A
D
R
V
P
A
L
V
V
A
R
A
S
G
----
L
P
G
V
G
A
-
V
-
R
G
D
D
V
A
G
I
T
L
A
V
D
H
L
T
E
L
-----
G
H
R
N
--
I
A
H
I
D
G
A
D
A
-------
P
G
G
A
D
R
R
--
A
G
F
L
A
A
M
D
R
H
G
L
S
A
S
A
T
V
V
T
G
-
G
T
T
E
T
E
G
-
A
E
G
-
M
H
T
L
L
-
E
M
P
-----
T
P
P
T
A
V
V
A
F
N
D
R
C
A
T
G
V
L
D
L
L
--
V
R
S
G
R
D
----
V
P
A
D
I
S
V
V
G
Y
D
D
S
R
L
A
R
I
P
-----
H
V
Q
M
T
T
I
S
Q
D
A
-
T
H
M
A
E
A
A
V
D
G
A
L
A
Q
I
--------------------------------------------------------------------------------------------------------------------------------------------
33
HHSearch
56.44
10%
-92
* C5 *
3BBL
4
?
A:
[29-227]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
M
---
V
R
E
A
G
A
V
N
Y
F
V
L
P
F
P
F
S
E
D
R
-----
S
Q
I
D
-------
I
-----
Y
R
D
L
I
---
R
-
S
G
N
V
D
G
F
V
L
S
S
I
N
Y
-
N
D
P
R
V
Q
F
-------
L
-------------
L
---------------
K
Q
K
F
P
F
V
A
F
G
R
S
N
P
D
----
W
D
F
A
W
-
V
-
D
I
D
G
T
A
G
T
R
Q
A
V
E
Y
L
I
G
R
-----
G
H
R
R
--
I
A
I
L
A
W
P
E
D
-------
S
R
V
G
N
D
R
L
-
Q
G
Y
L
E
A
M
Q
T
A
Q
L
P
I
E
T
G
Y
I
L
R
G
E
G
T
F
E
-
V
G
R
A
M
-
T
L
H
L
L
-
D
-
L
SPE--
R
R
P
T
A
I
M
T
L
N
D
T
M
A
I
G
A
M
A
A
A
--
R
E
R
G
L
T
----
I
G
T
D
L
A
I
I
G
F
D
D
A
P
M
V
Q
Y
L
-----
F
P
P
L
S
S
V
R
Q
P
I
-
A
E
A
G
R
K
C
I
E
L
L
V
A
I
V
--------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
56.09
21%
-69
- C5 -
1JR2
-
HEM4_HUMAN
A:
[96-238]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
Y
V
V
G
N
A
T
A
S
L
V
S
K
I
G
L
D
T
-
E
-
G
E
T
-
C
G
N
A
E
K
L
A
E
Y
I
C
S
R
---
E
S
S
A
L
P
--
L
L
F
P
C
G
N
L
K
-------
R
--------
E
I
L
P
K
A
L
K
D
K
G
I
A
M
E
S
I
T
V
Y
Q
T
V
A
H
P
G
-
I
-
Q
-----------------
G
N
L
N
S
--
Y
Y
S
Q
Q
G
V
P
A
S
I
T
F
F
--
S
P
S
G
L
T
--
Y
-
S
L
K
H
I
Q
--
E
L
S
G
D
N
I
D
Q
I
K
F
A
A
IG
P
T
T
A
R
A
L
A
A
Q
G
-
L
P
V
S
C
T
A
E
S
P
T
P
Q
A
L
--------------------------------------------------------------------------------------------------------------------------------------------
41
HHSearch
55.26
12%
-106
- C5 -
2HSG
-
CCPA_BACME
A:
[114-278]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
K
Q
V
D
G
I
I
F
M
S
G
N
V
-
T
E
E
H
V
E
E
-------
L
-------------
K
---------------
K
S
P
V
P
V
V
L
A
A
S
I
E
-
S
---
T
N
Q
I
P
S
-
V
-
T
I
D
Y
E
Q
A
A
F
D
A
V
Q
S
L
I
D
S
-----
G
H
K
N
--
I
A
F
V
S
G
T
L
E
-------
E
PINHAK
K
V
K
G
Y
K
R
A
L
T
E
S
G
L
P
V
R
D
S
Y
I
V
E
G
D
Y
T
Y
D
-
S
G
I
E
A
-
V
E
K
L
L
-
E
E
D
-----
E
K
P
T
A
I
F
V
G
T
D
E
M
A
L
G
V
I
H
G
A
--
Q
D
R
G
L
---
N
-
V
P
N
D
L
E
I
I
G
F
D
N
T
R
L
S
T
M
V
-----
R
P
Q
L
T
S
V
V
Q
P
M
-
Y
D
I
G
A
V
A
M
R
L
L
T
K
Y
M
--------------------------------------------------------------------------------------------------------------------------------------------
51
Fugue
54.94
20%
-27
- C3 -
3WAI
-
MALE_ECOLI
A:
[3-739]
G
M
K
I
E
EG
K
L
V
I
W
I
N
GDKG
Y
N
G
L
A
E
V
G
K
K
F
E
K
D
TG
I
K
V
T
V
E
H
P
DK
L
E
E
K
F
P
Q
V
A
ATGDGPD
I
I
F
W
AH
D
R
F
G
G
Y
A
Q
S
GLL
A
E
I
T
P
D
K
A
F
Q
D
K
L
Y
P
F
T
W
D
A
V
RYNGKLI
A
Y
P
I
A
V
E
A
L
S
L
I
Y
N
KDLLPNPPKTWEE
I
P
A
L
D
K
E
L
K
A
K
GKSA
L
M
F
NLQEPYFT
W
P
L
I
A
ADGGYAFKDVGVDN
A
G
A
K
A
G
L
T
F
L
V
D
L
I
K
N
KHMNADTD
Y
S
I
A
E
A
A
F
N
K
GETA
M
T
I
N
G
PWA
W
S
N
I
D
T
S
KVN
Y
G
V
T
V
L
P
T
F
KG
Q
P
S
K
P
FVGVL
S
A
G
I
N
AASPN
K
E
L
A
K
E
F
L
E
NYLLT
D
E
G
L
E
A
V
N
K
D
KPLGAVAL
K
S
Y
E
E
E
L
AKD
P
R
I
A
A
T
M
E
N
A
Q
K
GEIMPN
I
P
Q
M
S
A
F
W
Y
A
V
R
T
A
V
I
N
A
A
S
GRQT
V
D
E
A
L
K
D
A
Q
T
N
K
Q
W
Y
D
A
L
T
W
M
R
E
N
T
P
D
G
E
----
K
Y
D
E
---
Y
P
-
F
E
T
Y
G
V
I
S
W
W
D
Y
G
H
W
I
E
A
VA--
H
R
M
P
-------
I
-----
A
-------
N
-
P
F
Q
A
G
--
I
G
N
K
Y
N
N
-
V
P
---------------------------------------------------
G
A
S
S
F
F
T
A
E
N
E
S
Y
A
E
-
F
-
V
A
E
-
K
L
N
V
K
Y
V
V
S
D
I
E
M
E
---
T
G
K
------
Y
Y
A
M
A
V
W
A
-------
E
--------
G
D
L
--
P
L
A
E
K
Y
Y
G
G
--
Y
F
Y
Y
S
P
T
G
T
F
G
-
Y
-
A
N
S
-
Q
W
D
I
P
-
L
-
N
SIIIP
L
R
I
P
S
E
L
Y
Y
S
T
M
E
A
K
L
H
--
L
F
--
D
G
S
G
L
S
--
H
-----------
Y
R
M
I
Y
E
S
D
Y
-----
P
A
E
W
K
S
Y
S
S
Q
V
N
L
N
N
E
S
Q
V
L
Q
T
A
L
Y
E
A
V
M
R
A
R
Y
GVSPT
M
G
T
Q
E
V
L
Y
K
Y
A
Y
T
Q
LYEKKMG
I
P
V
K
IAPSGY
V
K
I
F
E
R
V
K
G
A
V
V
T
G
K
V
SANVT
E
V
S
V
N
A
T
I
K
T
NQN
R
T
F
E
Y
W
Q
T
V
E
V
K
NG
T
Y
T
V
V
L
PYSHNSDYPVKPIT
P
Y
H
I
K
AGN
V
V
K
E
I
T
I
Y
E
S
Q
V
Q
N
G
E
I
I
Q
L
D
L
34
HHSearch
54.78
12%
-90
- C5 -
3EGC
-
?
A:
[88-285]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
V
---
E
S
E
A
R
H
K
G
Y
S
V
L
L
A
N
T
A
E
D
I
-----
V
R
E
R
-------
E
A
----
V
G
Q
F
----
F
-
E
R
R
V
D
G
L
I
L
A
P
S
E
G
-
E
H
D
Y
L
R
T
-------
E
-------------
L
---------------
P
K
T
F
P
I
V
A
V
N
R
E
L
R
I
----
P
G
C
G
A
-
V
-
L
S
E
N
V
R
G
A
R
T
A
V
E
Y
L
I
A
R
-----
G
H
T
R
--
I
G
A
I
V
G
S
A
G
-------
L
M
T
S
R
E
R
L
-
K
G
F
R
A
A
M
S
A
A
G
L
P
V
R
Q
E
W
I
A
A
------N
G
-
R
D
G
-
A
I
K
V
L
-
T
G------
D
R
P
T
A
L
L
T
S
S
H
R
I
T
E
G
A
M
Q
A
L
--
N
V
L
G
L
R
----
Y
G
P
D
V
E
I
V
S
F
D
N
L
P
W
M
A
F
L
-----
D
P
P
L
P
V
V
E
Q
P
T
-
R
R
I
G
Q
E
A
M
R
M
L
I
H
M
I
--------------------------------------------------------------------------------------------------------------------------------------------
38
HHSearch
52.94
12%
-103
- C5 -
3E61
1
?
A:
[30-216]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
---
E
D
V
A
L
A
H
G
Y
Q
V
L
I
G
N
S
D
N
D
I
-----
K
K
A
Q
-------
G
Y
----
L
A
T
F
----
V
-
S
H
N
C
T
G
M
I
S
T
A
F
N
E
-
N
-
I
I
E
N
T
-------
L
-------------
T
---------------
D
-
H
I
P
F
V
F
I
D
R
I
N
-----------------
H
F
K
G
G
Q
L
Q
A
E
V
V
R
K
G
-----
K
G
K
N
--
V
L
I
V
H
E
N
L
L
-------
I
D
A
F
H
Q
R
V
-
Q
G
I
K
Y
I
L
D
Q
---
D
Y
K
M
L
E
A
T
L
---
L
-
D
-
N
-
D
K
K
-
F
I
D
L
I
-
K
-
E
-----
L
S
I
D
S
I
I
C
S
N
D
L
L
A
I
N
V
L
G
I
V
--
Q
R
Y
H
F
K
----
V
P
A
E
I
Q
I
I
G
Y
D
N
I
P
F
S
E
M
T
-----
Y
P
Q
I
T
T
I
D
Q
S
A
-
Y
H
L
G
E
I
A
V
S
Q
L
L
A
L
T
--------------------------------------------------------------------------------------------------------------------------------------------
37
HHSearch
51.27
13%
-102
- C5 -
2O20
2
?
A:
[118-278]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
Q
V
D
G
I
V
Y
M
G
S
S
L
-
D
E
K
I
R
T
S
-------
L
-------------
K
---------------
N
S
R
T
P
V
V
L
V
G
T
I
D
G
----
D
K
E
I
P
S
-
V
-
N
I
D
Y
H
L
A
A
Y
Q
S
T
K
K
L
I
D
S
-----
G
N
K
K
--
I
A
Y
I
M
G
S
L
K
D
V
E
N
T
E
R
M
--------
V
G
Y
Q
E
A
L
L
E
A
N
I
E
F
D
E
N
L
V
F
E
G
N
Y
S
Y
E
-
Q
-
G
K
A
L
A
E
R
L
L
---
E
-----
R
G
A
T
S
A
V
V
S
H
D
T
V
A
V
G
L
L
S
A
M
--
M
D
K
G
V
---
K
-
V
P
E
D
F
E
I
I
S
G
A
N
S
P
I
T
Q
Y
T
-----
Y
P
T
L
T
S
V
N
Q
P
L
-
Y
D
L
G
A
V
A
M
R
L
L
T
K
L
M
--------------------------------------------------------------------------------------------------------------------------------------------
30
HHSearch
50.97
15%
-61
- C5 -
3MW8
9
?
A:
[120-239]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
K
Q
I
V
I
V
R
G
K
G
G
----
R
E
A
M
---
A
D
G
L
R
L
R
G
A
N
V
S
Y
L
E
V
Y
Q
R
A
-----
C
P
P
L
-------
D
A
P
A
--
S
V
S
R
W
---
Q
-
S
F
G
I
D
T
I
V
V
T
S
G
E
V
-
L
E
N
L
I
N
L
V------
P
KDS
F
A
--------
W
---------------
L
R
D
C
H
I
I
V
P
S
A
R
V
E
T
Q
A
R
K
K
G
L
R
R
V
T
-
N
A
G
-
A
A
N
Q
A
A
V
L
D
A
L
G
M
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
HHSearch
49.89
11%
-94
- C5 -
3HUU
-
?
A:
[46-239]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
I
---
N
Q
A
C
N
V
R
G
Y
S
T
R
M
T
V
S
E
N
S
G
-----
D
L
Y
H
-------
E
V
----
K
T
M
I
----
Q
-
S
K
S
V
D
G
F
I
L
L
Y
S
L
K
-
D
D
P
I
E
H
L
-------
L
-------------
N
---------------
E
F
K
V
P
Y
L
I
V
G
K
S
L
N
Y
----
E
N
I
I
H
-
I
-
D
N
D
N
I
D
A
A
Y
Q
L
T
Q
Y
L
Y
H
L
-----
G
H
R
H
--
I
L
F
L
Q
E
S
G
H
Y
A
V
T
E
D
R
S
--------
V
G
F
K
Q
Y
C
D
D
V
K
I
S
N
D
C
V
V
I
K
S
M
---
N
D
-
L
-
R
D
F
-
I
-------------
H
M
P
S
V
I
I
T
S
D
V
M
L
N
M
Q
L
L
N
V
L
--
Y
E
Y
Q
L
---
R
-
I
P
E
D
I
Q
T
A
T
F
N
T
S
F
L
T
E
N
A
-----
T
P
S
Q
T
S
V
N
I
N
P
-
D
V
L
G
F
T
A
G
N
T
I
I
D
V
L
--------------------------------------------------------------------------------------------------------------------------------------------
28
HHSearch
49.40
18%
-55
- C5 -
3P9Z
1
?
A:
[110-224]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
K
S
V
L
Y
L
R
A
K
E
I
----
V
S
S
L
---
D
T
I
L
L
E
H
G
I
D
F
K
Q
A
V
V
Y
E
N
K
-----
L
K
H
L
-------
T
-----
L
S
E
Q
N
A
L
-
K
-
P
K
E
K
S
I
L
I
F
T
A
I
S
H
-
A
K
A
F
L
H
Y
F------
E
-------------
F
---------------
L
E
N
Y
T
A
I
S
I
G
N
T
T
A
L
Y
L
Q
E
Q
G
I
P
S
-
Y
-
I
A
K
-
K
P
S
L
E
A
C
L
E
L
A
L
S
L
---
R
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------